熔点	240 ºC (分解)**
密度	1.069±0.06 g/cm3 (20 º

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Methylseleninic acid (MSA) inhibits 17β-estradiol-induced cell growth in breast cancer T47D cells via enhancement of the antioxidative thioredoxin/ thioredoxin reductase system.Tomofumi Okuno et al.Biomedical research (Tokyo, Japan), 33(4), 201-210 (2012-09-15) Methaneseleninic acid is a substrate for truncated mammalian thioredoxin reductase: implications for the catalytic mechanism and redox signaling.Gregg Snider et al.Biochemistry, 49(48), 10329-10338 (2010-11-03) Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells.Yongmei Qi et al.The Journal of biological chemistry, 285(43), 33010-33017 (2010-08-17) Methylseleninic acid inhibits HDAC activity in diffuse large B-cell lymphoma cell lines.Shireen Kassam et al.Cancer chemotherapy and pharmacology, 68(3), 815-821 (2011-04-27) Methylseleninic acid restricts tumor growth in nude mice model of metastatic breast cancer probably via inhibiting angiopoietin-2.Xiaojing Wu et al.BMC cancer, 12, 192-192 (2012-05-30) Encapsulation of selenium in chitosan nanoparticles improves selenium availability and protects cells from selenium-induced DNA damage response.Shu Zhang et al.The Journal of nutritional biochemistry, 22(12), 1137-1142 (2011-02-05) Targeting Werner syndrome protein sensitizes U-2 OS osteosarcoma cells to selenium-induced DNA damage response and necrotic death.Wen-Hsing Cheng et al.Biochemical and biophysical research communications, 420(1), 24-28 (2012-03-07) Dietary supplementation with methylseleninic acid, but not selenomethionine, reduces spontaneous metastasis of Lewis lung carcinoma in mice.Lin Yan et al.International journal of cancer, 131(6), 1260-1266 (2011-11-19) Methylseleninic acid antagonizes the cytotoxic effect of bortezomib in mantle cell lymphoma cell lines through modulation of Bcl-2 family proteins.Shireen Kassam et al.British journal of haematology, 156(2), 286-289 (2011-09-14) Selenium for the prevention of cutaneous melanoma.Pamela B Cassidy et al.Nutrients, 5(3), 725-749 (2013-03-09) Crucial role of macrophage selenoproteins in experimental colitis.Naveen Kaushal et al.Journal of immunology (Baltimore, Md. : 1950), 193(7), 3683-3692 (2014-09-05) Niclosamide inhibits androgen receptor variants expression and overcomes enzalutamide resistance in castration-resistant prostate cancer.Chengfei Liu et al.Clinical cancer research : an official journal of the American Association for Cancer Research, 20(12), 3198-3210 (2014-04-18) Selenium suppresses leukemia through the action of endogenous eicosanoids.Ujjawal H Gandhi et al.Cancer research, 74(14), 3890-3901 (2014-05-30) Methylseleninic Acid Suppresses Breast Cancer Growth via the JAK2/STAT3 Pathway.Changwei Qiu et al.Reproductive sciences (Thousand Oaks, Calif.), 26(6), 829-838 (2018-12-12) Dietary selenium supplementation modifies breast tumor growth and metastasis.Yu-Chi Chen et al.International journal of cancer, 133(9), 2054-2064 (2013-04-25) Mouse prostate proteomes are differentially altered by supranutritional intake of four selenium compounds.Jinhui Zhang et al.Nutrition and cancer, 63(5), 778-789 (2011-05-27) Selenium supplementation suppresses immunological and serological features of lupus in B6.Sle1b mice.Chetna Soni et al.Autoimmunity, 52(2), 57-68 (2019-04-23) Methylseleninic acid enhances paclitaxel efficacy for the treatment of triple-negative breast cancer.Yanfeng Qi et al.PloS one, 7(2), e31539-e31539 (2012-02-22) Antioxidant and anticancer properties and mechanisms of inorganic selenium, oxo-sulfur, and oxo-selenium compounds.Ria R Ramoutar et al.Cell biochemistry and biophysics, 58(1), 1-23 (2010-07-16) Methylseleninic acid downregulates hypoxia-inducible factor-1α in invasive prostate cancer.Indu Sinha et al.International journal of cancer, 130(6), 1430-1439 (2011-04-19) Suppression of FOXO1 is responsible for a growth regulatory repressive transcriptional sub-signature of EWS-FLI1 in Ewing sarcoma.Niedan S, Kauer M, Aryee DN, et al. 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Inorganic Chemistry Communications, 15, 97-101 (2012) Proteomic profiling of potential molecular targets of methyl-selenium compounds in the transgenic adenocarcinoma of mouse prostate model.Jinhui Zhang et al.Cancer prevention research (Philadelphia, Pa.), 3(8), 994-1006 (2010-07-22) Activation of FOXO1 is critical for the anticancer effect of methylseleninic acid in prostate cancer cells.Haitao Zhang et al.The Prostate, 70(12), 1265-1273 (2010-07-14) Methylseleninic acid is a novel suppressor of aromatase expression.Ruijuan Gao et al.The Journal of endocrinology, 212(2), 199-205 (2011-12-01) Survivin gene silencing sensitizes prostate cancer cells to selenium growth inhibition.Xichun Liu et al.BMC cancer, 10, 418-418 (2010-08-12) Methylseleninic Acid Prevents Patulin-Induced Hepatotoxicity and Nephrotoxicity via the Inhibition of Oxidative Stress and Inactivation of p53 and MAPKs.Xiaotong Lu et al.Journal of agricultural and food chemistry, 65(26), 5299-5305 (2017-06-09) Allium chemistry: synthesis, natural occurrence, biological activity, and chemistry of Se-alk(en)ylselenocysteines and their gamma-glutamyl derivatives and oxidation products.E Block et al.Journal of agricultural and food chemistry, 49(1), 458-470 (2001-04-18)

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