熔点	165 ºC (分解)*
密度	4.0 g/cm3*

没有数据	没有数据

来源	SDS样本
没有数据	没有数据

产品合成路线

更多

名称	CAS号

更多

文章

同行评议文献

The fasciitis-panniculitis syndrome: clinical spectrum and response to cimetidine.J E Naschitz et al.Seminars in arthritis and rheumatism, 21(4), 211-220 (1992-02-01) Lobular carcinoma of the male breast associated with the use of cimetidine.P San Miguel et al.Virchows Archiv : an international journal of pathology, 430(3), 261-263 (1997-03-01) Modulation of tissue inflammatory response by histamine receptors in scorpion envenomation pathogenesis: involvement of H4 receptor.Amal Lamraoui et al.Inflammation, 37(5), 1689-1704 (2014-05-27) Cimetidine-associated optic neuropathy.M A Sa'adah et al.European neurology, 42(1), 23-26 (1999-07-08) Effect of premedications in a murine model of asparaginase hypersensitivity.Christian A Fernandez et al.The Journal of pharmacology and experimental therapeutics, 352(3), 541-551 (2015-01-13) Exacerbation of intracranial aneurysm and aortic dissection in hypertensive rat treated with the prostaglandin F-receptor antagonist AS604872.Miyuki Fukuda et al.Journal of pharmacological sciences, 126(3), 230-242 (2014-10-25) BODIPY(®) FL histamine as a new modality for quantitative detection of histamine receptor upregulation upon IgE sensitization in murine bone marrow-derived mast cells.Arash Mirzahosseini et al.Cytometry. Part A : the journal of the International Society for Analytical Cytology, 87(1), 23-31 (2014-09-13) [A case of acute interstitial nephritis and nonoliguria acute renal failure induced by cimetidine].S Koarada et al.Nihon Jinzo Gakkai shi, 34(11), 1227-1232 (1992-11-01) Clinical relevance of cimetidine drug interactions.A F Shinn Drug safety, 7(4), 245-267 (1992-07-01) Cimetidine synergizes with Praziquantel to enhance the immune response of HBV DNA vaccine via activating cytotoxic CD8(+) T cell.Xiaoping Xie et al.Human vaccines & immunotherapeutics, 10(6), 1688-1699 (2014-03-20) The contribution of human OCT1, OCT3, and CYP3A4 to nitidine chloride-induced hepatocellular toxicity.Liping Li et al.Drug metabolism and disposition: the biological fate of chemicals, 42(7), 1227-1234 (2014-04-30) Cimetidine in idiopathic urticaria.M Choy et al.DICP : the annals of pharmacotherapy, 25(6), 609-612 (1991-06-01) Four cation-selective transporters contribute to apical uptake and accumulation of metformin in Caco-2 cell monolayers.Tianxiang Kevin Han et al.The Journal of pharmacology and experimental therapeutics, 352(3), 519-528 (2015-01-08) Diclofenac toxicity in human intestine ex vivo is not related to the formation of intestinal metabolites.Xiaoyu Niu et al.Archives of toxicology, 89(1), 107-119 (2014-04-29) Cimetidine treatment for recurrent respiratory papillomatosis.J P Harcourt et al.International journal of pediatric otorhinolaryngology, 51(2), 109-113 (2000-01-05) Physical characterization of drug:polymer dispersion behavior in polyethylene glycol 4000 solid dispersions using a suite of complementary analytical techniques.Dipy M Vasa et al.Journal of pharmaceutical sciences, 103(9), 2911-2923 (2014-05-16) Effects of renal impairment on the pharmacokinetics of morinidazole: uptake transporter-mediated renal clearance of the conjugated metabolites.Kan Zhong et al.Antimicrobial agents and chemotherapy, 58(7), 4153-4161 (2014-05-14) In silico modeling of the molecular interactions of antacid medication with the endothelium: novel therapeutic implications in head and neck carcinomas.M Matossian et al.International journal of immunopathology and pharmacology, 27(4), 573-583 (2015-01-13) Cimetidine attenuates vinorelbine-induced phlebitis in mice by militating E-selectin expression.Zhuo Wang et al.Cancer chemotherapy and pharmacology, 74(2), 239-247 (2014-06-01) A comparison of histamine effects on the sympathetic neurotransmission of testicular capsule and rat vas deferens.Edilson Dantas da Silva Júnior et al.Naunyn-Schmiedeberg's archives of pharmacology, 387(8), 719-731 (2014-04-17) Gene therapy for unresectable hepatocellular carcinoma using recombinant human adenovirus type 5.Jun Dong et al.Medical oncology (Northwood, London, England), 31(8), 95-95 (2014-07-06) Involvement of H1 and H2 receptors and soluble guanylate cyclase in histamine-induced relaxation of rat mesenteric collecting lymphatics.Kristine H Kurtz et al.Microcirculation (New York, N.Y. : 1994), 21(7), 593-605 (2014-04-08) Pharmaceuticals in the freshwater invertebrate, Gammarus pulex, determined using pulverised liquid extraction, solid phase extraction and liquid chromatography-tandem mass spectrometry.Thomas H Miller et al.The Science of the total environment, 511, 153-160 (2014-12-30) Cimetidine. IARC monographs on the evaluation of carcinogenic risks to humans, 50, 235-263 (1990-01-01) Evaluation of sphingomyelin, cholester, and phosphatidylcholine-based immobilized artificial membrane liquid chromatography to predict drug penetration across the blood-brain barrier.Mike De Vrieze et al.Analytical and bioanalytical chemistry, 406(25), 6179-6188 (2014-08-16) Automation of a high risk medication regime algorithm in a home health care population.Catherine H Olson et al.Journal of biomedical informatics, 51, 60-71 (2014-04-17) Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.Shuang Wang et al.Human vaccines & immunotherapeutics, 10(2), 461-468 (2013-11-21) [Interaction between drugs. A critical assessment of various controlling factors in relation to clinical significance--exemplified by cimetidine].C E Elwin Nordisk medicin, 106(5), 151-154 (1991-01-01) [The effect of H2-receptor blockers (cimetidine and ranitidin) on parotid gland secretion and salivary carbonic anhydrase activity in the rat].I Boros et al.Fogorvosi szemle, 86(8), 265-273 (1993-08-01) Cimetidine and a delayed hypersensitivity reaction.R D Evans et al.Clinics in podiatric medicine and surgery, 17(2), 371-375 (2000-05-16) Does cimetidine improve prospects for cancer patients?. A reappraisal of the evidence to date.C P Siegers et al.Digestion, 60(5), 415-421 (1999-09-04) Protective Effect of Liriodendrin Isolated from Kalopanax pictus against Gastric Injury.Yoon Ah Sohn et al.Biomolecules & therapeutics, 23(1), 53-59 (2015-01-17) A primary fish gill cell culture model to assess pharmaceutical uptake and efflux: evidence for passive and facilitated transport.Lucy C Stott et al.Aquatic toxicology (Amsterdam, Netherlands), 159, 127-137 (2014-12-30) Development of a biomimetic phospholipid vesicle-based permeation assay for the estimation of intestinal drug permeability.Elenaz Naderkhani et al.Journal of pharmaceutical sciences, 103(6), 1882-1890 (2014-03-26) cIEF for rapid pKa determination of small molecules: a proof of concept.Stéphanie Romand et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 63, 14-21 (2014-07-06) Cimetidine, an unexpected anti-tumor agent, and its potential for the treatment of glioblastoma (review).Florence Lefranc et al.International journal of oncology, 28(5), 1021-1030 (2006-04-06) The cholinergic basal forebrain in the ferret and its inputs to the auditory cortex.Victoria M Bajo et al.The European journal of neuroscience, 40(6), 2922-2940 (2014-06-20) Histamine upregulates Nav1.8 expression in primary afferent neurons via H2 receptors: involvement in neuropathic pain.Jia-Xing Yue et al.CNS neuroscience & therapeutics, 20(10), 883-892 (2014-07-06) Effects of cucurbitacin e, a tetracyclic triterpene compound from Cucurbitaceae, on the pharmacokinetics and pharmacodynamics of warfarin in rats.Tonggui Ding et al.Basic & clinical pharmacology & toxicology, 116(5), 385-389 (2014-09-25) [Gastrin, insulin and glucagon secretion after cimetidine and sodium hydrocarbonate intake in patients with duodenal ulcer].L N Valenkevich et al.Klinicheskaia meditsina, 69(3), 91-93 (1991-03-01) Cimetidine: an anticancer drug?Martina Kubecova et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 42(5), 439-444 (2011-02-19) Organic cation transporter/solute carrier family 22a is involved in drug transfer into milk in mice.Naoki Ito et al.Journal of pharmaceutical sciences, 103(10), 3342-3348 (2014-09-02) Cimetidine: a review of the recent developments and reports in cutaneous medicine.Noah Scheinfeld Dermatology online journal, 9(2), 4-4 (2003-03-18) Cimetidine in the treatment of acute intermittent porphyria.P D Rogers The Annals of pharmacotherapy, 31(3), 365-367 (1997-03-01) Validation of phenol red versus gravimetric method for water reabsorption correction and study of gender differences in Doluisio's absorption technique.Fatmanur Tuğcu-Demiröz et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 62, 105-110 (2014-06-03) Histamine in the locus coeruleus promotes descending noradrenergic inhibition of neuropathic hypersensitivity.Hong Wei et al.Pharmacological research, 90, 58-66 (2014-10-12) Evidence for organic cation transporter-mediated metformin transport and 5'-adenosine monophosphate-activated protein kinase activation in rat skeletal muscles.Rieko Oshima et al.Metabolism: clinical and experimental, 64(2), 296-304 (2014-12-01) Identification of the rat liver cytochrome P450 enzymes involved in the metabolism of the calcium channel blocker dipfluzine hydrochloride.Wei Guo et al.Environmental toxicology and pharmacology, 38(3), 901-912 (2014-12-03) Altered esophageal histamine receptor expression in Eosinophilic Esophagitis (EoE): implications on disease pathogenesis.Jamie Merves et al.PloS one, 10(2), e0114831-e0114831 (2015-02-28) Knock-in model of Dravet syndrome reveals a constitutive and conditional reduction in sodium current.Ryan J Schutte et al.Journal of neurophysiology, 112(4), 903-912 (2014-05-09) [Endocrine effect of cimetidine].I I Dedov et al.Klinicheskaia meditsina, 71(2), 11-16 (1993-01-01) A plasma cell variant of Castleman's disease treated successfully with cimetidine. Case report and review of the literature.V Barbounis et al.Anticancer research, 16(1), 545-547 (1996-01-01) Cimetidine: an immunomodulator.A Kumar DICP : the annals of pharmacotherapy, 24(3), 289-295 (1990-03-01)

备注