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2-Furancarboxylic acid propyl ester | CAS:615-10-1
2-Furancarboxylic acid propyl ester
  • 名称:2-呋喃甲酸丙酯 | 2-Furancarboxylic acid propyl ester
  • CAS号:615-10-1
  • 别名:NSC 35559; Propyl 2-furancarboxylate; Propyl 2-furoate; Propyl alpha-furoate
  • 分子式:C8H10O3
  • 分子量:154.16
  • EINESC号:210-407-7

产品描述

物理化学性质

沸点 213 ºC
闪点 82 ºC
密度 1.077

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SDS

来源 SDS样本
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Astemizole and an analogue promote fungicidal activity of fluconazole against Cryptococcus neoformans var. grubii and Cryptococcus gattii.Kiem Vu et al.Medical mycology, 48(2), 255-262 (2009-07-03) Identification of KvLQT1 K+ channels as new regulators of non-small cell lung cancer cell proliferation and migration.Alban Girault et al.International journal of oncology, 44(3), 838-848 (2013-12-25) On-chip constructive cell-network study (II): on-chip quasi-in vivo cardiac toxicity assay for ventricular tachycardia/fibrillation measurement using ring-shaped closed circuit microelectrode with lined-up cardiomyocyte cell network.Fumimasa Nomura et al.Journal of nanobiotechnology, 9, 39-39 (2011-09-21) Selective interaction of lansoprazole and astemizole with tau polymers: potential new clinical use in diagnosis of Alzheimer's disease.Leonel E Rojo et al.Journal of Alzheimer's disease : JAD, 19(2), 573-589 (2010-01-30) Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.Caroline A Lee et al.Drug metabolism and disposition: the biological fate of chemicals, 40(5), 943-951 (2012-02-14) Torsades de pointes ventricular tachycardia associated with overdose of astemizole.K A Rao et al.Mayo Clinic proceedings, 69(6), 589-593 (1994-06-01) Astemizole synergizes calcitriol antiproliferative activity by inhibiting CYP24A1 and upregulating VDR: a novel approach for breast cancer therapy.Janice García-Quiroz et al.PloS one, 7(9), e45063-e45063 (2012-09-18) Astemizole: an old anti-histamine as a new promising anti-cancer drug.Janice García-Quiroz et al.Anti-cancer agents in medicinal chemistry, 11(3), 307-314 (2011-03-30) Mapping pharmaceuticals in rat brain sections using MALDI imaging mass spectrometry.Yunsheng Hsieh et al.Methods in molecular biology (Clifton, N.J.), 656, 147-158 (2010-08-04) Regulation of IGF-1-dependent cyclin D1 and E expression by hEag1 channels in MCF-7 cells: the critical role of hEag1 channels in G1 phase progression.Anne-Sophie Borowiec et al.Biochimica et biophysica acta, 1813(5), 723-730 (2011-02-15) Development of QTc prolongation model incorporating circadian rhythm using harmonic model.Hyun-moon Back et al.Xenobiotica; the fate of foreign compounds in biological systems, 45(5), 420-427 (2014-12-06) Arrhythmias after astemizole overdose.S M Heidemann et al.Pediatric emergency care, 12(2), 102-104 (1996-04-01) Bridging Functional and Structural Cardiotoxicity Assays Using Human Embryonic Stem Cell-Derived Cardiomyocytes for a More Comprehensive Risk Assessment.Mike Clements et al.Toxicological sciences : an official journal of the Society of Toxicology, 148(1), 241-260 (2015-08-12) An ion channel library for drug discovery and safety screening on automated platforms.Barbara A Wible et al.Assay and drug development technologies, 6(6), 765-780 (2008-12-19) Simultaneous gene expression signature of heart and peripheral blood mononuclear cells in astemizole-treated rats.Eun-Hee Lee et al.Archives of toxicology, 84(8), 609-618 (2010-03-12) Tuning of EAG K(+) channel inactivation: molecular determinants of amplification by mutations and a small molecule.Vivek Garg et al.The Journal of general physiology, 140(3), 307-324 (2012-08-30) Protein binding-dependent decreases in hERG channel blocker potency assessed by whole-cell voltage clamp in serum.Michael Margulis et al.Journal of cardiovascular pharmacology, 55(4), 368-376 (2010-02-04) A human ether-á-go-go-related (hERG) ion channel atomistic model generated by long supercomputer molecular dynamics simulations and its use in predicting drug cardiotoxicity.Anwar Anwar-Mohamed et al.Toxicology letters, 230(3), 382-392 (2014-08-17) Astemizole. A review of its pharmacodynamic properties and therapeutic efficacy.D M Richards et al.Drugs, 28(1), 38-61 (1984-07-01) Unique drug screening approach for prion diseases identifies tacrolimus and astemizole as antiprion agents.Yervand Eduard Karapetyan et al.Proceedings of the National Academy of Sciences of the United States of America, 110(17), 7044-7049 (2013-04-12) Ventricular fibrillation and anoxic encephalopathy secondary to astemizole overdose.T G Burke et al.The Annals of pharmacotherapy, 27(2), 239-241 (1993-02-01) Structural and functional screening in human induced-pluripotent stem cell-derived cardiomyocytes accurately identifies cardiotoxicity of multiple drug types.Kimberly R Doherty et al.Toxicology and applied pharmacology, 285(1), 51-60 (2015-04-07) Visualizing voltage dynamics in zebrafish heart.Hidekazu Tsutsui et al.The Journal of physiology, 588(Pt 12), 2017-2021 (2010-04-28) Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist.Anima Ghosal et al.Drug metabolism and disposition: the biological fate of chemicals, 39(1), 30-38 (2010-10-12) MALDI-tandem mass spectrometry imaging of astemizole and its primary metabolite in rat brain sections.Fangbiao Li et al.Bioanalysis, 1(2), 299-307 (2009-05-01) A trivalent approach for determining in vitro toxicology: Examination of oxime K027.Adriana Prado et al.Journal of applied toxicology : JAT, 35(2), 219-227 (2014-05-24) Sustainable synthesis of diverse privileged heterocycles by palladium-catalyzed aerobic oxidative isocyanide insertion.Tjøstil Vlaar et al.Angewandte Chemie (International ed. in English), 51(52), 13058-13061 (2012-11-20) Species differences in intestinal metabolic activities of cytochrome P450 isoforms between cynomolgus monkeys and humans.Haruka Nishimuta et al.Drug metabolism and pharmacokinetics, 26(3), 300-306 (2011-03-09) Chloroquine-astemizole hybrids with potent in vitro and in vivo antiplasmodial activity.Chitalu C Musonda et al.Bioorganic & medicinal chemistry letters, 19(2), 481-484 (2008-12-05) Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast.Hanna Phan et al.Drugs, 69(18), 2541-2576 (2009-12-01) Antihistamines modulate the integrin signaling pathway in h9c2 rat cardiomyocytes: Possible association with cardiotoxicity.J S Yun et al.Human & experimental toxicology, 34(8), 796-807 (2014-11-27) Characterization of the active site properties of CYP4F12.John Eksterowicz et al.Drug metabolism and disposition: the biological fate of chemicals, 42(10), 1698-1707 (2014-07-31) Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy.Philip E D Chung et al.Nature communications, 11(1), 1825-1825 (2020-04-15) Astemizole effects on skin testing.C L Hedrick et al.The Annals of pharmacotherapy, 26(11), 1388-1389 (1992-11-01) The possible involvement of hyperpolarizing mechanisms in histamine-induced relaxation of the rat portal vein.Patrícia de S Rossignoli et al.Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 44(3-4), 129-141 (2008-10-04) Improved methodology for identifying the teratogenic potential in early drug development of hERG channel blocking drugs.M F Nilsson et al.Reproductive toxicology (Elmsford, N.Y.), 29(2), 156-163 (2010-02-11) [Astemizole: its pharmacokinetics and pharmacologic properties].J C Levron et al.Allergie et immunologie, 22(6), 233-241 (1990-06-01) Danazol Inhibits Cytochrome P450 2J2 Activity in a Substrate-independent Manner.Eunyoung Lee et al.Drug metabolism and disposition: the biological fate of chemicals, 43(8), 1250-1253 (2015-06-07) Potential of decursin to inhibit the human cytochrome P450 2J2 isoform.Boram Lee et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 70, 94-99 (2014-05-03) An aqueous extract of Poncirus fructus activates the prokinetic activity of 5-HT receptor subtype 4 without hERG interaction.Won-Sik Shim et al.Journal of ethnopharmacology, 132(1), 328-333 (2010-08-26) [Efficacy and safety of astemizole in the treatment of allergic rhinitis and urticaria: a systematic review with meta-analysis].Pedro Gutiérrez Castrellón et al.Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993), 52(3), 113-126 (2005-09-15) A panel of cytochrome P450 BM3 variants to produce drug metabolites and diversify lead compounds.Andrew M Sawayama et al.Chemistry (Weinheim an der Bergstrasse, Germany), 15(43), 11723-11729 (2009-09-24) Astemizole: a long-acting, nonsedating antihistamine.P M Krstenansky et al.Drug intelligence & clinical pharmacy, 21(12), 947-953 (1987-12-01) Astemizole. A nonsedating antihistamine with fast and sustained activity.M M Janssens Clinical reviews in allergy, 11(1), 35-63 (1993-01-01) Novel method for action potential measurements from intact cardiac monolayers with multiwell microelectrode array technology.Heather B Hayes et al.Scientific reports, 9(1), 11893-11893 (2019-08-17) Onset of action of astemizole.M M Janssens et al.International journal of clinical pharmacology research, 11(5), 219-229 (1991-01-01) Efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenia patients with moderate thrombocytopenia.Hawk Kim et al.Annals of hematology, 94(5), 739-746 (2014-12-17) Differential effects of blockade of ERG channels on gamma oscillations and excitability in rat hippocampal slices.Silvia Fano et al.The European journal of neuroscience, 36(12), 3628-3635 (2012-10-12)
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