熔点	35-39 ºC
沸点	133-135 ºC (15 mmHg)
闪点	>110 ºC
密度	1.101
折射率	1.5

危险品标志	C
危险类别码	R34
安全说明书	S26;S27;S36/37/39;S45

来源	SDS样本
Alfa-Aesar	浏览或下载
Sigma-Aldrich	浏览或下载
TCI	浏览或下载

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In Barrett's esophagus patients and Barrett's cell lines, ursodeoxycholic acid increases antioxidant expression and prevents DNA damage by bile acids.Sui Peng et al.American journal of physiology. Gastrointestinal and liver physiology, 307(2), G129-G139 (2014-05-24) Bile acids: regulation of apoptosis by ursodeoxycholic acid.Joana D Amaral et al.Journal of lipid research, 50(9), 1721-1734 (2009-05-07) Sex and age are determinants of the clinical phenotype of primary biliary cirrhosis and response to ursodeoxycholic acid.Marco Carbone et al.Gastroenterology, 144(3), 560-569 (2012-12-19) How I manage sinusoidal obstruction syndrome after haematopoietic cell transplantation.Enric Carreras British journal of haematology, 168(4), 481-491 (2014-11-18) [A clinical study of bilirubin rise in short-term in patients with primary biliary cirrhosis].Yan-min Liu et al.Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 20(8), 632-633 (2012-12-12) New method for the determination of bile acids in human plasma by liquid-phase microextraction using liquid chromatography-ion-trap-time-of-flight mass spectrometry.Maria José Nunes de Paiva et al.Journal of chromatography. A, 1388, 102-109 (2015-02-28) Ursodeoxycholic acid for the treatment of primary biliary cirrhosis.Keith Lindor The New England journal of medicine, 357(15), 1524-1529 (2007-10-12) [Review of overlap syndromes in autoimmune liver diseases. Diagnostic and therapeutic difficulties].Krisztina Hagymási et al.Orvosi hetilap, 154(24), 923-929 (2013-06-12) Ursocholanic acid rescues mitochondrial function in common forms of familial Parkinson's disease.Heather Mortiboys et al.Brain : a journal of neurology, 136(Pt 10), 3038-3050 (2013-09-04) Efficacy of ursodeoxycholic acid in treating intrahepatic cholestasis of pregnancy: a meta-analysis.Yannick Bacq et al.Gastroenterology, 143(6), 1492-1501 (2012-08-16) Hydroxylation of lithocholic acid by selected actinobacteria and filamentous fungi.V V Kollerov et al.Steroids, 78(3), 370-378 (2013-01-22) Early biochemical response to ursodeoxycholic acid and long-term prognosis of primary biliary cirrhosis: results of a 14-year cohort study.Li-Na Zhang et al.Hepatology (Baltimore, Md.), 58(1), 264-272 (2013-02-15) Ursodeoxycholic acid for primary biliary cirrhosis.Yan Gong et al.The Cochrane database of systematic reviews, (3)(3), CD000551-CD000551 (2008-08-05) Matrix effects break the LC behavior rule for analytes in LC-MS/MS analysis of biological samples.Nianbai Fang et al.Experimental biology and medicine (Maywood, N.J.), 240(4), 488-497 (2014-10-12) Severe hepatitis induced by cyproterone acetate: role of corticosteroids. A case report.Ludovico Abenavoli et al.Annals of hepatology, 12(1), 152-155 (2013-01-08) Clinical efficacy and effectiveness of ursodeoxycholic acid in cholestatic liver diseases.Davide Festi et al.Current clinical pharmacology, 2(2), 155-177 (2008-08-12) Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management.John E Eaton et al.Gastroenterology, 145(3), 521-536 (2013-07-06) Plasma phospholipids identify antecedent memory impairment in older adults.Mark Mapstone et al.Nature medicine, 20(4), 415-418 (2014-03-13) Differential regulation of EGFR-MAPK signaling by deoxycholic acid (DCA) and ursodeoxycholic acid (UDCA) in colon cancer.Sara M Centuori et al.Digestive diseases and sciences, 59(10), 2367-2380 (2014-07-17) [The use of hepatic protectors in clinical practice].O N Minushkin et al.Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 112(10 Pt 2), 67-72 (2012-12-20) [Using ursodez in the treatment of refractory form of gastroesophageal reflux disease].A M Osadchuk et al.Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, (4)(4), 74-75 (2013-02-14) Ursodeoxycholic acid therapy in gallbladder disease, a story not yet completed.Michele Pier Luca Guarino et al.World journal of gastroenterology, 19(31), 5029-5034 (2013-08-22) Primary sclerosing cholangitis, Crohn's disease and HLA-B27 in black South African women.O C Buchel et al.Acta gastro-enterologica Belgica, 75(4), 454-457 (2013-02-14) [Intrahepatic cholestasis of pregnancy].St Pevtichev et al.Akusherstvo i ginekologiia, 52(1), 35-41 (2013-06-29) Primary sclerosing cholangitis, Crohn's disease and HLA-B27 in black South African women.O C Buchel et al.Acta gastro-enterologica Belgica, 75(4), 454-457 (2013-02-14) Study on formability of solid nanosuspensions during solidification: II novel roles of freezing stress and cryoprotectant property.Peng-Fei Yue et al.International journal of pharmaceutics, 475(1-2), 35-48 (2014-08-27) [Innovations in the diagnosis and treatment of cholelithiasis].R A Ivanchenkova et al.Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, (4)(4), 66-73 (2013-02-14) Refeeding syndrome in a patient with advanced kidney failure due to nephronophthisis.Kamel El-Reshaid Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 24(6), 1217-1222 (2013-11-16) Use of ursodiol in a patient with biliary cirrhosis.T G Vondracek et al.Clinical pharmacy, 11(8), 672-673 (1992-08-01) Value of baseline platelet count for prediction of complications in primary biliary cirrhosis patients treated with ursodeoxycholic acid.Yuan-Lan Huang et al.Scandinavian journal of clinical and laboratory investigation, 73(1), 17-23 (2013-01-09) Individual bile acids have differential effects on bile acid signaling in mice.Peizhen Song et al.Toxicology and applied pharmacology, 283(1), 57-64 (2015-01-15) Bile acids trigger cholemic nephropathy in common bile-duct-ligated mice.Peter Fickert et al.Hepatology (Baltimore, Md.), 58(6), 2056-2069 (2013-07-03) Ursodiol for hepatobiliary disorders.R A Rubin et al.Annals of internal medicine, 121(3), 207-218 (1994-08-01) Treatment of NASH with ursodeoxycholic acid: pro.Vlad Ratziu Clinics and research in hepatology and gastroenterology, 36 Suppl 1, S41-S45 (2012-11-13) Study on formability of solid nanosuspensions during solidification: II novel roles of freezing stress and cryoprotectant property.Peng-Fei Yue et al.International journal of pharmaceutics, 475(1-2), 35-48 (2014-08-27) Effect of ursodeoxycholic acid use on the risk of colorectal neoplasia in patients with primary sclerosing cholangitis and inflammatory bowel disease: a systematic review and meta-analysis.Siddharth Singh et al.Inflammatory bowel diseases, 19(8), 1631-1638 (2013-05-15) Not all PBC is the same!Ansgar W Lohse et al.Gastroenterology, 144(3), 494-497 (2013-01-29) Cytotoxic bile acids, but not cytoprotective species, inhibit the ordering effect of cholesterol in model membranes at physiologically active concentrations.João Mello-Vieira et al.Biochimica et biophysica acta, 1828(9), 2152-2163 (2013-06-12) Novel gut-based pharmacology of metformin in patients with type 2 diabetes mellitus.Antonella Napolitano et al.PloS one, 9(7), e100778-e100778 (2014-07-06) Functional analysis of ABCB4 mutations relates clinical outcomes of progressive familial intrahepatic cholestasis type 3 to the degree of MDR3 floppase activity.Raquel Gordo-Gilart et al.Gut, 64(1), 147-155 (2014-03-07) [Management of PBC cases failing to respond to UDCA].Atsushi Tanaka Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 110(1), 16-21 (2013-01-11) Metabolomics of Ramadan fasting: an opportunity for the controlled study of physiological responses to food intake.Sweety Mathew et al.Journal of translational medicine, 12, 161-161 (2014-06-08) [Primary and secondary prevention of alcoholic liver cirrhosis].S A Beliakin et al.Voenno-meditsinskii zhurnal, 334(3), 15-19 (2013-07-03) Ursodeoxycholic acid in chronic hepatitis C.Raoul Poupon et al.Gut, 56(12), 1652-1653 (2007-11-14) Ursodeoxycholic acid for cystic fibrosis-related liver disease.Katharine Cheng et al.The Cochrane database of systematic reviews, 10, CD000222-CD000222 (2012-10-19) Ursodeoxycholic acid in cholestasis: linking action mechanisms to therapeutic applications.Marcelo G Roma et al.Clinical science (London, England : 1979), 121(12), 523-544 (2011-08-23) How I manage sinusoidal obstruction syndrome after haematopoietic cell transplantation.Enric Carreras British journal of haematology, 168(4), 481-491 (2014-11-18) [A clinical study of bilirubin rise in short-term in patients with primary biliary cirrhosis].Yan-min Liu et al.Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 20(8), 632-633 (2012-12-12) New method for the determination of bile acids in human plasma by liquid-phase microextraction using liquid chromatography-ion-trap-time-of-flight mass spectrometry.Maria José Nunes de Paiva et al.Journal of chromatography. A, 1388, 102-109 (2015-02-28) Ursodeoxycholic acid for the treatment of primary biliary cirrhosis.Keith Lindor The New England journal of medicine, 357(15), 1524-1529 (2007-10-12) [Review of overlap syndromes in autoimmune liver diseases. Diagnostic and therapeutic difficulties].Krisztina Hagymási et al.Orvosi hetilap, 154(24), 923-929 (2013-06-12) Glucocorticoid receptor-dependent immunomodulatory effect of ursodeoxycholic acid on liver lymphocytes in mice.Toshimichi Takigawa et al.American journal of physiology. Gastrointestinal and liver physiology, 305(6), G427-G438 (2013-07-23) Stability of ursodiol in SyrSpend SF Cherry flavored.Christine M Geiger et al.International journal of pharmaceutical compounding, 16(6), 510-512 (2012-12-25) Treatment of paediatric cholestasis due to canalicular transport defects: yet another step forward.Jose J G Marin et al.Gut, 64(1), 6-8 (2014-05-28) Omega-3 polyunsaturated fatty acid and ursodeoxycholic acid have an additive effect in attenuating diet-induced nonalcoholic steatohepatitis in mice.Ja Kyung Kim et al.Experimental & molecular medicine, 46, e127-e127 (2014-12-20) B-cell depletion with rituximab in patients with primary biliary cirrhosis refractory to ursodeoxycholic acid.Robert P Myers et al.The American journal of gastroenterology, 108(6), 933-941 (2013-05-08) Sex and age are determinants of the clinical phenotype of primary biliary cirrhosis and response to ursodeoxycholic acid.Marco Carbone et al.Gastroenterology, 144(3), 560-569 (2012-12-19) All-trans-retinoic acid improves cholestasis in α-naphthylisothiocyanate-treated rats and Mdr2-/- mice.Shi-Ying Cai et al.The Journal of pharmacology and experimental therapeutics, 349(1), 94-98 (2014-02-05) Levels of alkaline phosphatase and bilirubin are surrogate end points of outcomes of patients with primary biliary cirrhosis: an international follow-up study.Willem J Lammers et al.Gastroenterology, 147(6), 1338-1349 (2014-08-28) Ursodiol to prevent hepatic venoocclusive disease.S A Comcowich et al.The Annals of pharmacotherapy, 31(10), 1249-1252 (1997-10-24) Ursodeoxycholic acid and bile-acid mimetics as therapeutic agents for cholestatic liver diseases: an overview of their mechanisms of action.Raoul Poupon Clinics and research in hepatology and gastroenterology, 36 Suppl 1, S3-12 (2012-11-13) New enzymatic assay for the AKR1C enzymes.Nataša Beranič et al.Chemico-biological interactions, 202(1-3), 204-209 (2012-12-25) Ursodiol and colorectal cancer or dysplasia risk in primary sclerosing cholangitis and inflammatory bowel disease: a meta-analysis.Jonathan D Hansen et al.Digestive diseases and sciences, 58(11), 3079-3087 (2013-07-31) Ursodeoxycholic acid for patients with primary biliary cirrhosis: an updated systematic review and meta-analysis of randomized clinical trials using Bayesian approach as sensitivity analyses.Yan Gong et al.The American journal of gastroenterology, 102(8), 1799-1807 (2007-04-27) Effects of antioxidant agents against cyclosporine-induced hepatotoxicity.Sami Akbulut et al.The Journal of surgical research, 193(2), 658-666 (2014-10-05) A novel high-pressure precipitation tandem homogenization technology for drug nanocrystals production - a case study with ursodeoxycholic acid.Yu Li et al.Pharmaceutical development and technology, 19(6), 662-670 (2013-07-23) Ursodeoxycholic acid-conjugated chitosan for photodynamic treatment of HuCC-T1 human cholangiocarcinoma cells.Hye Myeong Lee et al.International journal of pharmaceutics, 454(1), 74-81 (2013-07-10) Not all PBC is the same!Ansgar W Lohse et al.Gastroenterology, 144(3), 494-497 (2013-01-29) [Innovations in the diagnosis and treatment of cholelithiasis].R A Ivanchenkova et al.Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, (4)(4), 66-73 (2013-02-14) Refeeding syndrome in a patient with advanced kidney failure due to nephronophthisis.Kamel El-Reshaid Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 24(6), 1217-1222 (2013-11-16) Use of ursodiol in a patient with biliary cirrhosis.T G Vondracek et al.Clinical pharmacy, 11(8), 672-673 (1992-08-01) Value of baseline platelet count for prediction of complications in primary biliary cirrhosis patients treated with ursodeoxycholic acid.Yuan-Lan Huang et al.Scandinavian journal of clinical and laboratory investigation, 73(1), 17-23 (2013-01-09) Individual bile acids have differential effects on bile acid signaling in mice.Peizhen Song et al.Toxicology and applied pharmacology, 283(1), 57-64 (2015-01-15) Bile acids trigger cholemic nephropathy in common bile-duct-ligated mice.Peter Fickert et al.Hepatology (Baltimore, Md.), 58(6), 2056-2069 (2013-07-03) Ursodiol for hepatobiliary disorders.R A Rubin et al.Annals of internal medicine, 121(3), 207-218 (1994-08-01) Treatment of NASH with ursodeoxycholic acid: pro.Vlad Ratziu Clinics and research in hepatology and gastroenterology, 36 Suppl 1, S41-S45 (2012-11-13) [Intrahepatic cholestasis of pregnancy].St Pevtichev et al.Akusherstvo i ginekologiia, 52(1), 35-41 (2013-06-29) Effect of ursodeoxycholic acid use on the risk of colorectal neoplasia in patients with primary sclerosing cholangitis and inflammatory bowel disease: a systematic review and meta-analysis.Siddharth Singh et al.Inflammatory bowel diseases, 19(8), 1631-1638 (2013-05-15) Prevention and treatment of intestinal failure-associated liver disease in children.Bram P Raphael et al.Seminars in liver disease, 32(4), 341-347 (2013-02-12) Cytotoxic bile acids, but not cytoprotective species, inhibit the ordering effect of cholesterol in model membranes at physiologically active concentrations.João Mello-Vieira et al.Biochimica et biophysica acta, 1828(9), 2152-2163 (2013-06-12) Novel gut-based pharmacology of metformin in patients with type 2 diabetes mellitus.Antonella Napolitano et al.PloS one, 9(7), e100778-e100778 (2014-07-06) Functional analysis of ABCB4 mutations relates clinical outcomes of progressive familial intrahepatic cholestasis type 3 to the degree of MDR3 floppase activity.Raquel Gordo-Gilart et al.Gut, 64(1), 147-155 (2014-03-07) [Management of PBC cases failing to respond to UDCA].Atsushi Tanaka Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 110(1), 16-21 (2013-01-11) Metabolomics of Ramadan fasting: an opportunity for the controlled study of physiological responses to food intake.Sweety Mathew et al.Journal of translational medicine, 12, 161-161 (2014-06-08) [Primary and secondary prevention of alcoholic liver cirrhosis].S A Beliakin et al.Voenno-meditsinskii zhurnal, 334(3), 15-19 (2013-07-03) Ursodeoxycholic acid in chronic hepatitis C.Raoul Poupon et al.Gut, 56(12), 1652-1653 (2007-11-14) Ursodeoxycholic acid for cystic fibrosis-related liver disease.Katharine Cheng et al.The Cochrane database of systematic reviews, 10, CD000222-CD000222 (2012-10-19) Ursodeoxycholic acid for primary biliary cirrhosis.Yan Gong et al.The Cochrane database of systematic reviews, (3)(3), CD000551-CD000551 (2008-08-05) Bile acids: regulation of apoptosis by ursodeoxycholic acid.Joana D Amaral et al.Journal of lipid research, 50(9), 1721-1734 (2009-05-07)

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