沸点	204-205 ºC
闪点	76 ºC
密度	0.997
折射率	1.56-1.562

安全说明书	S23;S24/25

来源	SDS样本
Alfa-Aesar	浏览或下载
Sigma-Aldrich	浏览或下载
TCI	浏览或下载

产品合成路线

更多

名称	CAS号

更多

文章

同行评议文献

Noninvasive molecular imaging of hypoxia in human xenografts: comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers.Fuqiu He et al.Cancer research, 68(20), 8597-8606 (2008-10-17) Mechanisms for the anti-hepatitis B virus activity and mitochondrial toxicity of fialuridine (FIAU).J M Colacino Antiviral research, 29(2-3), 125-139 (1996-03-01) In vivo evaluation of the uptake of [(123)I]FIAU, [(123)I]IVFRU and [(123)I]IVFAU by normal mouse brain: potential for noninvasive assessment of HSV-1 thymidine kinase gene expression in gliomas.H-F Li et al.Nucleosides, nucleotides & nucleic acids, 27(1), 57-66 (2008-01-12) Comparison of cell-labeling methods with ¹²⁴I-FIAU and ⁶⁴Cu-PTSM for cell tracking using chronic myelogenous leukemia cells expressing HSV1-tk and firefly luciferase.Jae-Jun Park et al.Cancer biotherapy & radiopharmaceuticals, 27(10), 719-728 (2012-09-27) In vivo trafficking and immunostimulatory potential of an intranasally-administered primary dendritic cell-based vaccine.Prachi Vilekar et al.BMC immunology, 11, 60-60 (2010-12-15) Imaging of a localized bacterial infection with endogenous thymidine kinase using radioisotope-labeled nucleosides.Su Jin Jang et al.International journal of medical microbiology : IJMM, 302(2), 101-107 (2012-01-24) The use of 14C-FIAU to predict bacterial thymidine kinase presence: implications for radiolabeled FIAU bacterial imaging.Kristin L Peterson et al.Nuclear medicine and biology, 40(5), 638-642 (2013-04-02) Bortezomib-induced enzyme-targeted radiation therapy in herpesvirus-associated tumors.De-Xue Fu et al.Nature medicine, 14(10), 1118-1122 (2008-09-09) Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts.Lewis W, et al. Proceedings of the National Academy of Sciences of the USA, 93(8), 3592-3597 (1996) Herpes simplex virus thymidine kinase imaging in mice with (1-(2'-deoxy-2'-[18F]fluoro-1-β-D-arabinofuranosyl)-5-iodouracil) and metabolite (1-(2'-deoxy-2'-[18F]fluoro-1-β-D-arabinofuranosyl)-5-uracil).Sridhar Nimmagadda et al.European journal of nuclear medicine and molecular imaging, 36(12), 1987-1993 (2009-06-10) Effects of structural differences between radioiodine-labeled 1-(2'-fluoro-2'-deoxy-D-arabinofuranosyl)-5-iodouracil (FIAU) and 1-(2'-fluoro-2'-deoxy-d-ribofuranosyl)-5-iodouracil (FIRU) on HSV1-TK reporter gene imaging.Eun Jung Kim et al.Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 68(6), 971-978 (2010-01-20) Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B.McKenzie R, et al. The New England Journal of Medicine, 333(17), 1099-1105 (1995) Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes.Rajgopal Govindarajan et al.American journal of physiology. Gastrointestinal and liver physiology, 295(3), G570-G580 (2008-07-19) Comparative study of cellular kinetics of reporter probe [(131)I]FIAU in neonatal cardiac myocytes after transfer of HSV1-tk reporter gene with two vectors.Xiaoli Lan et al.Nuclear medicine and biology, 36(2), 207-213 (2009-02-17) 5-[18F]Fluoroalkyl pyrimidine nucleosides: probes for positron emission tomography imaging of herpes simplex virus type 1 thymidine kinase gene expression.Ann-Marie Chacko et al.Nuclear medicine and biology, 36(1), 29-38 (2009-02-03) Improved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickase.Reto Eggenschwiler et al.Scientific reports, 6, 38198-38198 (2016-12-03) Toxicology. 'Humanized' mouse detects deadly drug side effects.Jon Cohen Science (New York, N.Y.), 344(6181), 244-245 (2014-04-20) Fialuridine accumulates in DNA of dogs, monkeys, and rats following long-term oral administration.Richardson FC, et al. Proceedings of the National Academy of Sciences of the USA, 91(25), 12003-12007 (1994) Biodistribution, cellular uptake and DNA-incorporation of the 2'-fluoro stabilized 5-iodo-2'-deoxyuridine analog 5-iodo-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil (FIAU).A Morgenroth et al.The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., 52(3), 305-316 (2008-04-25) Imaging of gene expression in live pancreatic islet cell lines using dual-isotope SPECT.Joo Ho Tai et al.Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 49(1), 94-102 (2007-12-14) Enhanced antitumor effects by combination gene therapy using MDR1 gene shRNA and HSV1-tk in a xenograft mouse model.Sang-Woo Lee et al.Cancer letters, 291(1), 83-89 (2009-11-10) Letter to the editor.Martin G Pomper Seminars in nuclear medicine, 39(5), 354-354 (2009-08-04) Evaluation of F-18-labeled 5-iodocytidine (18F-FIAC) as a new potential positron emission tomography probe for herpes simplex virus type 1 thymidine kinase imaging.Pei-Chia Chan et al.Nuclear medicine and biology, 38(7), 987-995 (2011-10-11) Bacterial thymidine kinase as a non-invasive imaging reporter for Mycobacterium tuberculosis in live animals.Stephanie L Davis et al.PloS one, 4(7), e6297-e6297 (2009-07-17) The improved syntheses of 5-substituted 2'-[18F]fluoro-2'-deoxy-arabinofuranosyluracil derivatives ([18F]FAU, [18F]FEAU, [18F]FFAU, [18F]FCAU, [18F]FBAU and [18F]FIAU) using a multistep one-pot strategy.Hancheng Cai et al.Nuclear medicine and biology, 38(5), 659-666 (2011-07-02) Efficient targeting and tumor retardation effect of pancreatic adenocarcinoma up-regulated factor (PAUF)-specific RNA replacement in pancreatic cancer mouse model.Yun-Hee Kim et al.Cancer letters, 344(2), 223-231 (2013-11-06) Monitoring bone marrow stem cells with a reporter gene system in experimental middle cerebral artery occlusion rat models.Tao Wu et al.Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(6), 984-989 (2013-03-29) Improved synthesis of 2'-deoxy-2'-[18F]-fluoro-1-beta-D-arabinofuranosyl-5-iodouracil ([18F]-FIAU).Harry Anderson et al.Nuclear medicine and biology, 37(4), 439-442 (2010-05-08) Mitochondrial injury. Lessons from the fialuridine trial.P Honkoop et al.Drug safety, 17(1), 1-7 (1997-07-01) A multimodality reporter gene for monitoring transplanted stem cells.Zhijun Pei et al.Nuclear medicine and biology, 39(6), 813-820 (2012-02-18)

备注