水溶性	起反应
沸点	80 ºC (0.4 mmHg)
闪点	40 ºC
密度	1.082
折射率	1.472-1.474

危险品标志	T;N
危险类别码	R10;R15;R21;R25;R36/38;R48/23/25
安全说明书	S35;S36/37/39;S45;S60;S61

来源	SDS样本
Alfa-Aesar	浏览或下载
Sigma-Aldrich	浏览或下载
TCI	浏览或下载

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名称	CAS号

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Optimization of the selective preparation of 20(R)-ginsenoside Rg3 catalyzed by d, l-tartaric acid using response surface methodology.Chengpeng Sun et al.Fitoterapia, 84, 213-221 (2012-12-12) Anti-breast cancer activity of Fine Black ginseng (Panax ginseng Meyer) and ginsenoside Rg5.Shin-Jung Kim et al.Journal of ginseng research, 39(2), 125-134 (2015-06-06) [Effect of ginsenoside Rg3 on hepatic fibrosis in murine schistosomiasis japonica].Jin Zeng et al.Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 29(2), 107-110 (2011-08-11) Characterization of Panax ginseng UDP-Glycosyltransferases Catalyzing Protopanaxatriol and Biosyntheses of Bioactive Ginsenosides F1 and Rh1 in Metabolically Engineered Yeasts.Wei Wei et al.Molecular plant, 8(9), 1412-1424 (2015-06-03) Synergistic effect of curcumin on epigallocatechin gallate-induced anticancer action in PC3 prostate cancer cells.Dae-Woon Eom et al.BMB reports, 48(8), 461-466 (2014-12-03) Ginsenoside Rg3 inhibits lipopolysaccharide-induced adhesion molecule expression in human umbilical vein endothelial cell and C57BL/6 mice.Young-Suk Cho et al.Die Pharmazie, 69(11), 818-822 (2015-05-20) Toxicity of a novel anti-tumor agent 20(S)-ginsenoside Rg3: a 26-week intramuscular repeated administration study in rats.J-P Liu et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(10), 3388-3396 (2012-07-24) Ginsenoside Rg3 attenuates cell migration via inhibition of aquaporin 1 expression in PC-3M prostate cancer cells.Xue-Yang Pan et al.European journal of pharmacology, 683(1-3), 27-34 (2012-03-20) Stereospecific antioxidant effects of ginsenoside Rg3 on oxidative stress induced by cyclophosphamide in mice.Xiaojie Wei et al.Fitoterapia, 83(4), 636-642 (2012-02-09) Mass production of the ginsenoside Rg3(S) through the combinative use of two glycoside hydrolases.Jin-Kwang Kim et al.Food chemistry, 141(2), 1369-1377 (2013-06-26) Drug-mediated shortening of action potentials in LQTS2 human induced pluripotent stem cell-derived cardiomyocytesDuncan G, et al. Stem Cells and Development, 26(23), 1695-1705 (2017) Ginsenoside Rg3 enhances the chemosensitivity of tumors to cisplatin by reducing the basal level of nuclear factor erythroid 2-related factor 2-mediated heme oxygenase-1/NAD(P)H quinone oxidoreductase-1 and prevents normal tissue damage by scavenging cisplatin-induced intracellular reactive oxygen species.Chang Ki Lee et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(7), 2565-2574 (2012-01-24) Ginsenoside Rg(3) decelerates hERG K(+) channel deactivation through Ser631 residue interaction.Choi SH, Shin TJ, Hwang SH, Lee BH, Kang J, Kim HJ, Jo SH, Choe H, Nah SY. European Journal of Pharmacology, 1-3, 59-67 (2011) Enzymatic biotransformation of ginsenoside Rb1 to 20(S)-Rg3 by recombinant β-glucosidase from Microbacterium esteraromaticum.Lin-Hu Quan et al.Applied microbiology and biotechnology, 94(2), 377-384 (2012-01-18) Simultaneous determination of 11 major components in Palmul-tang by HPLC-DAD and LC-MS-MS.Bohyoung Lee et al.Journal of chromatographic science, 52(6), 482-492 (2013-06-07) Ginsenoside Rg3 inhibits endothelial progenitor cell differentiation through attenuation of VEGF-dependent Akt/eNOS signaling.Jae-Won Kim et al.Phytotherapy research : PTR, 26(9), 1286-1293 (2012-01-19) Red ginseng extract promotes the hair growth in cultured human hair follicles.Gyeong-Hun Park et al.Journal of medicinal food, 18(3), 354-362 (2014-11-15) Fermented Ginseng Extract, BST204, Suppresses Tumorigenesis and Migration of Embryonic Carcinoma through Inhibition of Cancer Stem Cell Properties.Jong Woo Park et al.Molecules (Basel, Switzerland), 25(14) (2020-07-12) Ginsenoside fractions regulate the action of monocytes and their differentiation into dendritic cells.Yeo Jin Lee et al.Journal of ginseng research, 39(1), 29-37 (2014-12-24) Reactive oxygen species mediated ginsenoside Rg3- and Rh2-induced apoptosis in hepatoma cells through mitochondrial signaling pathways.Hye-Min Park et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(8), 2736-2741 (2012-05-29) The amelioration of N-acetyl-p-benzoquinone imine toxicity by ginsenoside Rg3: the role of Nrf2-mediated detoxification and Mrp1/Mrp3 transports.Sang Il Gum et al.Oxidative medicine and cellular longevity, 2013, 957947-957947 (2013-06-15) Red ginseng and 20(S)-Rg3 control testosterone-induced prostate hyperplasia by deregulating androgen receptor signaling.Jung-Soo Bae et al.Journal of natural medicines, 66(3), 476-485 (2011-11-22) Ginsenoside Rg3 reduces lipid accumulation with AMP-Activated Protein Kinase (AMPK) activation in HepG2 cells.Seohyun Lee et al.International journal of molecular sciences, 13(5), 5729-5739 (2012-07-04) Proteomic analysis of the anti-cancer effect of 20S-ginsenoside Rg3 in human colon cancer cell lines.Lee SY, Kim GT, Roh SH, Song JS, Kim HJ, Hong SS, Kwon SW, Park JH. Bioscience, Biotechnology, and Biochemistry, 4, 811-816 (2009) Stereospecific effects of ginsenoside 20-Rg3 inhibits TGF-β1-induced epithelial-mesenchymal transition and suppresses lung cancer migration, invasion and anoikis resistance.Young-Joo Kim et al.Toxicology, 322, 23-33 (2014-05-06) American ginseng significantly reduced the progression of high-fat-diet-enhanced colon carcinogenesis in Apc (Min/+) mice.Chunhao Yu et al.Journal of ginseng research, 39(3), 230-237 (2015-07-23) Ginsenoside Rg3 suppresses the NLRP3 inflammasome activation through inhibition of its assembly.Yuhua Shi et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(1), 208-221 (2020-01-10) Ginsenoside Rg3 attenuates tumor angiogenesis via inhibiting bioactivities of endothelial progenitor cells.Jae-Won Kim et al.Cancer biology & therapy, 13(7), 504-515 (2012-03-13) Dammarane triterpenes as potential SIRT1 activators from the leaves of Panax ginseng.Jun-Li Yang et al.Journal of natural products, 77(7), 1615-1623 (2014-06-28) Protective effects of ginsenoside Rg3 on human osteoarthritic chondrocytes.Min Wook So et al.Modern rheumatology, 23(1), 104-111 (2012-03-29) Ginsenoside Rg3 improves cardiac mitochondrial population quality: mimetic exercise training.Mengwei Sun et al.Biochemical and biophysical research communications, 441(1), 169-174 (2013-10-22) Effect of 20(S)-ginsenoside Rg3 on streptozotocin-induced experimental type 2 diabetic rats: a urinary metabonomics study by rapid-resolution liquid chromatography/mass spectrometry.Jun Niu et al.Rapid communications in mass spectrometry : RCM, 26(23), 2683-2689 (2012-11-06) Cytoprotective effect of 20S-Rg3 on benzo[a]pyrene-induced DNA damage.Po Ying Poon et al.Drug metabolism and disposition: the biological fate of chemicals, 40(1), 120-129 (2011-10-01) Ginsenoside Rg3 inhibit hepatocellular carcinoma growth via intrinsic apoptotic pathway.Jian-Wen Jiang et al.World journal of gastroenterology, 17(31), 3605-3613 (2011-10-12) Selected ginsenosides of the protopanaxdiol series are novel positive allosteric modulators of P2X7 receptors.R M Helliwell et al.British journal of pharmacology, 172(13), 3326-3340 (2015-03-11) Ginsenoside Rg3 attenuates microglia activation following systemic lipopolysaccharide treatment in mice.Sun-Min Park et al.Biological & pharmaceutical bulletin, 35(9), 1546-1552 (2012-09-15) Antioxidative, anti-inflammatory, and matrix metalloproteinase inhibitory activities of 20(S)-ginsenoside Rg3 in cultured mammalian cell lines.Yu-Mi Shin et al.Molecular biology reports, 40(1), 269-279 (2012-10-12) Conversion of protopanaxadiol type saponins to ginsenoside Rg3 by lemon.Cheng-Peng Sun et al.Natural product communications, 7(9), 1155-1156 (2012-10-19) Ginsenoside Rb1 inhibits fibrillation and toxicity of alpha-synuclein and disaggregates preformed fibrils.Mustafa T Ardah et al.Neurobiology of disease, 74, 89-101 (2014-12-03) 20(s)-ginsenoside Rg3 promotes apoptosis in human ovarian cancer HO-8910 cells through PI3K/Akt and XIAP pathways.Jia-He Wang et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(12), 11985-11994 (2014-08-30) Stereospecificity of ginsenoside Rg3 in promotion of the immune response to ovalbumin in mice.Xiaojie Wei et al.International immunology, 24(7), 465-471 (2012-03-20) Novel roles of ginsenoside Rg3 in apoptosis through downregulation of epidermal growth factor receptor.Eun Ji Joo et al.Chemico-biological interactions, 233, 25-34 (2015-04-01) Comparative study on intestinal metabolism and absorption in vivo of ginsenosides in sulphur-fumigated and non-fumigated ginseng by ultra performance liquid chromatography quadruple time-of-flight mass spectrometry based chemical profiling approach.He Zhu et al.Drug testing and analysis, 7(4), 320-330 (2014-05-24) Enhanced oral bioavailability and anti-tumour effect of paclitaxel by 20(s)-ginsenoside Rg3 in vivo.Lei-Qiong Yang et al.Biopharmaceutics & drug disposition, 33(8), 425-436 (2012-08-18) Chronic treatment with ginsenoside Rg3 induces Akt-dependent senescence in human glioma cells.Seong Sin et al.International journal of oncology, 41(5), 1669-1674 (2012-08-28) Microbial transformation of ginsenoside Rg3 to ginsenoside Rh2 by Esteya vermicola CNU 120806.Jingang Hou et al.World journal of microbiology & biotechnology, 28(4), 1807-1811 (2012-07-19) Pharmacokinetics, bioavailability, and metabolism of Notoginsenoside Fc in rats by liquid chromatography/electrospray ionization tandem mass spectrometry.Chunyong He et al.Journal of pharmaceutical and biomedical analysis, 109, 150-157 (2015-03-17) Stereoisomers ginsenosides-20(S)-Rg₃ and -20(R)-Rg₃ differentially induce angiogenesis through peroxisome proliferator-activated receptor-gamma.Hoi-Hin Kwok et al.Biochemical pharmacology, 83(7), 893-902 (2012-01-12) Ginsenoside Rg3 regulates S-nitrosylation of the NLRP3 inflammasome via suppression of iNOS.Sung-Jin Yoon et al.Biochemical and biophysical research communications, 463(4), 1184-1189 (2015-06-19) Ginsenoside Rg3 inhibits growth and epithelial-mesenchymal transition of human oral squamous carcinoma cells by down-regulating miR-221.Zhou Cheng et al.European journal of pharmacology, 853, 353-363 (2019-04-01) Stereoisomer-specific anticancer activities of ginsenoside Rg3 and Rh2 in HepG2 cells: disparity in cytotoxicity and autophagy-inducing effects due to 20(S)-epimers.Jong Hye Cheong et al.Biological & pharmaceutical bulletin, 38(1), 102-108 (2015-03-07) Neuroprotective effect of 20(R)-ginsenoside Rg(3) against transient focal cerebral ischemia in rats.Bo He et al.Neuroscience letters, 526(2), 106-111 (2012-08-29) Immunopotentiation and antitumor effects of a ginsenoside Rg₃-fortified red ginseng preparation in mice bearing H460 lung cancer cells.Dongsun Park et al.Environmental toxicology and pharmacology, 31(3), 397-405 (2011-07-27)

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