
2-Methoxy-4-methylbenzoic acid | CAS:704-45-0
2-Methoxy-4-methylbenzoic acid
- 名称:2-甲氧基-4-甲基苯甲酸 | 2-Methoxy-4-methylbenzoic acid
- CAS号:704-45-0
- 别名:
- 分子式:C9H10O3
- 分子量:166.17
- EINESC号:
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High-throughput, luciferase-based reverse genetics systems for identifying inhibitors of Marburg and Ebola viruses.Luke S Uebelhoer et al.Antiviral research, 106, 86-94 (2014-04-10)
Sofosbuvir and ribavirin in HCV genotypes 2 and 3.Stefan Zeuzem et al.The New England journal of medicine, 370(21), 1993-2001 (2014-05-06)
Randomized trial of peginterferon alpha-2b plus low and escalating dose of ribavirin in patients with chronic hepatitis C with high viral load genotype 1.Yoshiaki Iwasaki et al.Journal of medical virology, 87(4), 625-633 (2015-01-23)
Conformational changes induced in the eukaryotic translation initiation factor eIF4E by a clinically relevant inhibitor, ribavirin triphosphate.Laurent Volpon et al.Biochemical and biophysical research communications, 434(3), 614-619 (2013-04-16)
Sofosbuvir for previously untreated chronic hepatitis C infection.Eric Lawitz et al.The New England journal of medicine, 369(7), 678-679 (2013-08-16)
Safety and on-treatment efficacy of telaprevir: the early access programme for patients with advanced hepatitis C.M Colombo et al.Gut, 63(7), 1150-1158 (2013-11-10)
Yakammaoto inhibits enterovirus 71 infection by reducing viral attachment, internalization, replication, and translation.Chia-Feng Yeh et al.The Kaohsiung journal of medical sciences, 31(6), 293-302 (2015-06-05)
Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial.Eric Lawitz et al.Lancet (London, England), 383(9916), 515-523 (2013-11-12)
The influence of hepatitis B virus on antiviral treatment with interferon and ribavirin in Asian patients with hepatitis C virus/hepatitis B virus coinfection: a meta-analysis.Jun-Ying Liu et al.Virology journal, 9, 186-186 (2012-09-07)
Insulin resistance as a predictor of early virologic response to HCV therapy among chronic HCV Egyptian patients.Ekram W Abd El-Wahab et al.Journal of medical virology, 87(3), 428-440 (2015-01-15)
Real life experience in treatment of HIV-1/HCV-coinfected patients with pegylated interferon alpha and ribavirin: predictors of SVR.Giuseppe Bruno et al.The new microbiologica, 38(1), 21-27 (2015-03-06)
Ribavirin-resistant variants of foot-and-mouth disease virus: the effect of restricted quasispecies diversity on viral virulence.Jianxiong Zeng et al.Journal of virology, 88(8), 4008-4020 (2014-01-24)
Efficacy and Tolerability of Peginterferon alpha-2a and Peginterferon alpha-2b in Iranian Patients With Chronic Hepatitis C.Mahdiyar Pouresmaeeli et al.Hepatitis monthly, 15(9), e30780-e30780 (2015-10-28)
Sadness and mild cognitive impairment as predictors for interferon-alpha-induced depression in patients with hepatitis C.Susanne Sarkar et al.The British journal of psychiatry : the journal of mental science, 206(1), 45-51 (2014-11-02)
Ombitasvir (ABT-267), a novel NS5A inhibitor for the treatment of hepatitis C.Guido Stirnimann Expert opinion on pharmacotherapy, 15(17), 2609-2622 (2014-10-28)
Weight loss with interferon and ribavirin therapy in chronic hepatitis C patients.Shaimuna Fareeha Sajjad et al.JPMA. The Journal of the Pakistan Medical Association, 62(11), 1229-1232 (2013-07-23)
Liver injury with novel oral anticoagulants: assessing post-marketing reports in the US Food and Drug Administration adverse event reporting system.Emanuel Raschi et al.British journal of clinical pharmacology, 80(2), 285-293 (2015-02-18)
Efficacy of pegylated interferon and ribavirin combination therapy for patients with hepatitis C virus infection after curative resection or ablation for hepatocellular carcinoma--A retrospective multicenter study.Naoki Harada et al.Journal of medical virology, 87(7), 1199-1206 (2015-03-17)
Statin therapy improves response to interferon alfa and ribavirin in chronic hepatitis C: a systematic review and meta-analysis.Qianqian Zhu et al.Antiviral research, 98(3), 373-379 (2013-04-23)
Editorial: can we afford the new direct-acting antivirals for treatment of genotype 1 hepatitis C?S E Congly et al.Alimentary pharmacology & therapeutics, 40(8), 983-984 (2014-09-18)
Quantum leaps, microeconomics, and the treatment of patients with hepatitis C and HIV coinfection.Michael S Saag JAMA, 312(4), 347-348 (2014-07-20)
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.Hiba Ahmad Zahreddine et al.Nature, 511(7507), 90-93 (2014-05-30)
Baseline factors associated with treatment response in patients infected with hepatitis C virus 1b by stratification of IL28B polymorphisms.Qihua Ling et al.Archives of virology, 160(4), 1105-1112 (2015-02-18)
The combination of MK-5172, peginterferon, and ribavirin is effective in treatment-naive patients with hepatitis C virus genotype 1 infection without cirrhosis.Michael P Manns et al.Gastroenterology, 147(2), 366-376 (2014-04-15)
Monocyte activation by interferon α is associated with failure to achieve a sustained virologic response after treatment for hepatitis C virus infection.Dennis J Hartigan-O'Connor et al.The Journal of infectious diseases, 209(10), 1602-1612 (2013-12-12)
Controlling hepatitis C with simeprevir.Geoffrey Dusheiko The Lancet. Infectious diseases, 15(1), 2-4 (2014-12-09)
Mutations in coronavirus nonstructural protein 10 decrease virus replication fidelity.Everett Clinton Smith et al.Journal of virology, 89(12), 6418-6426 (2015-04-10)
Validity of aspartate aminotransferase to platelet ratio index as predictor of early viral response in patients with hepatitis C treated by interferon-based therapy.Shaikh Samiullah et al.JPMA. The Journal of the Pakistan Medical Association, 62(10), 1008-1011 (2013-07-23)
In vitro combinations containing Tegobuvir are highly efficient in curing cells from HCV replicon and in delaying/preventing the development of drug resistance.Inge Vliegen et al.Antiviral research, 120, 112-121 (2015-06-04)
Sequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in Mosquitoes.Greta A Van Slyke et al.PLoS pathogens, 11(6), e1005009-e1005009 (2015-06-27)
In vitro combinations containing Tegobuvir are highly efficient in curing cells from HCV replicon and in delaying/preventing the development of drug resistance.Inge Vliegen et al.Antiviral research, 120, 112-121 (2015-06-04)
Validity of aspartate aminotransferase to platelet ratio index as predictor of early viral response in patients with hepatitis C treated by interferon-based therapy.Shaikh Samiullah et al.JPMA. The Journal of the Pakistan Medical Association, 62(10), 1008-1011 (2013-07-23)
Sequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in Mosquitoes.Greta A Van Slyke et al.PLoS pathogens, 11(6), e1005009-e1005009 (2015-06-27)
High-throughput, luciferase-based reverse genetics systems for identifying inhibitors of Marburg and Ebola viruses.Luke S Uebelhoer et al.Antiviral research, 106, 86-94 (2014-04-10)
Randomized trial of peginterferon alpha-2b plus low and escalating dose of ribavirin in patients with chronic hepatitis C with high viral load genotype 1.Yoshiaki Iwasaki et al.Journal of medical virology, 87(4), 625-633 (2015-01-23)
Yakammaoto inhibits enterovirus 71 infection by reducing viral attachment, internalization, replication, and translation.Chia-Feng Yeh et al.The Kaohsiung journal of medical sciences, 31(6), 293-302 (2015-06-05)
Conformational changes induced in the eukaryotic translation initiation factor eIF4E by a clinically relevant inhibitor, ribavirin triphosphate.Laurent Volpon et al.Biochemical and biophysical research communications, 434(3), 614-619 (2013-04-16)
The combination of MK-5172, peginterferon, and ribavirin is effective in treatment-naive patients with hepatitis C virus genotype 1 infection without cirrhosis.Michael P Manns et al.Gastroenterology, 147(2), 366-376 (2014-04-15)
Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial.Eric Lawitz et al.Lancet (London, England), 383(9916), 515-523 (2013-11-12)
Sofosbuvir for previously untreated chronic hepatitis C infection.Eric Lawitz et al.The New England journal of medicine, 369(7), 678-679 (2013-08-16)
Safety and on-treatment efficacy of telaprevir: the early access programme for patients with advanced hepatitis C.M Colombo et al.Gut, 63(7), 1150-1158 (2013-11-10)
Side effects of antiviral therapy in hepatitis C virus infection-sarcoidosis - case report.D Teodor et al.Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi, 116(4), 1039-1043 (2013-05-25)
Treatment for cryoglobulinemic and non-cryoglobulinemic peripheral neuropathy associated with hepatitis C virus infection.Tim J Benstead et al.The Cochrane database of systematic reviews, 12(12), CD010404-CD010404 (2014-12-20)
Interferon-ribavirin therapy induces serum antibodies determining 'rods and rings' pattern in hepatitis C patients.Cristina Novembrino et al.Journal of viral hepatitis, 21(12), 944-949 (2014-07-22)
Modeling viral kinetics and treatment outcome during alisporivir interferon-free treatment in hepatitis C virus genotype 2 and 3 patients.Jeremie Guedj et al.Hepatology (Baltimore, Md.), 59(5), 1706-1714 (2014-01-01)
Predictive value of interferon-lambda gene polymorphisms for treatment response in chronic hepatitis C.Simone Susser et al.PloS one, 9(11), e112592-e112592 (2014-11-14)
Synergistic suppression of dengue virus replication using a combination of nucleoside analogs and nucleoside synthesis inhibitors.Kim Long Yeo et al.Antimicrobial agents and chemotherapy, 59(4), 2086-2093 (2015-01-28)
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Ribavirin enhances myeloid-derived suppressor cell differentiation through CXCL9/10 downregulation.Jingyin Dong et al.Immunopharmacology and immunotoxicology, 36(6), 412-419 (2014-09-26)
Novel composed galactosylated nanodevices containing a ribavirin prodrug as hepatic cell-targeted carriers for HCV treatment.Emanuela Fabiola Craparo et al.Journal of biomedical nanotechnology, 9(6), 1107-1122 (2013-07-19)
Pretreatment serum macrophage inflammatory protein (MIP)-1 levels predict sustained virological responses to re-treatment in patients with chronic hepatitis C virus infection.Shibin Zhang et al.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 33, 15-21 (2014-12-03)
Daclatasvir plus sofosbuvir for previously treated or untreated chronic HCV infection.Mark S Sulkowski et al.The New England journal of medicine, 370(3), 211-221 (2014-01-17)
Genotype-Associated Differential NKG2D Expression on CD56+CD3+ Lymphocytes Predicts Response to Pegylated-Interferon/Ribavirin Therapy in Chronic Hepatitis C.Po-sung Chu et al.PloS one, 10(5), e0125664-e0125664 (2015-05-13)
Sofosbuvir and ribavirin for treatment of compensated recurrent hepatitis C virus infection after liver transplantation.Michael Charlton et al.Gastroenterology, 148(1), 108-117 (2014-10-12)
Homeostasis model assessment of insulin resistance does not seem to predict response to telaprevir in chronic hepatitis C in the REALIZE trial.Zobair Younossi et al.Hepatology (Baltimore, Md.), 58(6), 1897-1906 (2014-01-03)
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Association between response to pegylated interferon/ribavirin therapy and ribavirin levels.Chia-Yen Dai et al.Hepatology (Baltimore, Md.), 61(1), 408-409 (2014-04-23)
An antiviral drug screening system for enterovirus 71 based on an improved plaque assay: A potential high-throughput method.Yingxian Yin et al.Journal of medical virology, 91(8), 1440-1447 (2019-03-23)
Gene expression profiling to predict and assess the consequences of therapy-induced virus eradication in chronic hepatitis C virus infection.Jun Hou et al.Journal of virology, 88(21), 12254-12264 (2014-08-08)
Genetic Variability of Hepatitis C Virus (HCV) 5' Untranslated Region in HIV/HCV Coinfected Patients Treated with Pegylated Interferon and Ribavirin.Iwona Bukowska-Ośko et al.PloS one, 10(5), e0125604-e0125604 (2015-05-02)
An interferon-free antiviral regimen for HCV after liver transplantation.Paul Y Kwo et al.The New England journal of medicine, 371(25), 2375-2382 (2014-11-12)
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The influence of hepatitis B virus on antiviral treatment with interferon and ribavirin in Asian patients with hepatitis C virus/hepatitis B virus coinfection: a meta-analysis.Jun-Ying Liu et al.Virology journal, 9, 186-186 (2012-09-07)
Insulin resistance as a predictor of early virologic response to HCV therapy among chronic HCV Egyptian patients.Ekram W Abd El-Wahab et al.Journal of medical virology, 87(3), 428-440 (2015-01-15)
Ribavirin-resistant variants of foot-and-mouth disease virus: the effect of restricted quasispecies diversity on viral virulence.Jianxiong Zeng et al.Journal of virology, 88(8), 4008-4020 (2014-01-24)
Real life experience in treatment of HIV-1/HCV-coinfected patients with pegylated interferon alpha and ribavirin: predictors of SVR.Giuseppe Bruno et al.The new microbiologica, 38(1), 21-27 (2015-03-06)
Serum proteome predicts virological response in chronic hepatitis C genotype 1b patients treated with pegylated interferon plus ribavirin.Yi-Hao Yen et al.Journal of the Formosan Medical Association = Taiwan yi zhi, 114(7), 652-658 (2013-07-03)
Attenuation of vesicular stomatitis virus infection of brain using antiviral drugs and an adeno-associated virus-interferon vector.Guido Wollmann et al.Virology, 475, 1-14 (2014-12-03)
Efficacy and Tolerability of Peginterferon alpha-2a and Peginterferon alpha-2b in Iranian Patients With Chronic Hepatitis C.Mahdiyar Pouresmaeeli et al.Hepatitis monthly, 15(9), e30780-e30780 (2015-10-28)
Therapeutic potential of antiviral drugs targeting chemorefractory colorectal adenocarcinoma cells overexpressing endogenous retroviral elements.David Díaz-Carballo et al.Journal of experimental & clinical cancer research : CR, 34, 81-81 (2015-08-12)
Sadness and mild cognitive impairment as predictors for interferon-alpha-induced depression in patients with hepatitis C.Susanne Sarkar et al.The British journal of psychiatry : the journal of mental science, 206(1), 45-51 (2014-11-02)
Editorial: can we afford the new direct-acting antivirals for treatment of genotype 1 hepatitis C?S E Congly et al.Alimentary pharmacology & therapeutics, 40(8), 983-984 (2014-09-18)
Quantum leaps, microeconomics, and the treatment of patients with hepatitis C and HIV coinfection.Michael S Saag JAMA, 312(4), 347-348 (2014-07-20)
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.Hiba Ahmad Zahreddine et al.Nature, 511(7507), 90-93 (2014-05-30)
HCV therapy with daclatasvir, PEG-IFN, and RBV after boceprevir-based therapy failure post-liver transplantation in hyper-IgM syndrome.K Rajender Reddy et al.Transplantation, 97(8), e47-e48 (2014-04-16)
Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a randomised, double-blind, placebo-controlled phase 3 trial.Michael Manns et al.Lancet (London, England), 384(9941), 414-426 (2014-06-08)
Ombitasvir (ABT-267), a novel NS5A inhibitor for the treatment of hepatitis C.Guido Stirnimann Expert opinion on pharmacotherapy, 15(17), 2609-2622 (2014-10-28)
Weight loss with interferon and ribavirin therapy in chronic hepatitis C patients.Shaimuna Fareeha Sajjad et al.JPMA. The Journal of the Pakistan Medical Association, 62(11), 1229-1232 (2013-07-23)
Liver injury with novel oral anticoagulants: assessing post-marketing reports in the US Food and Drug Administration adverse event reporting system.Emanuel Raschi et al.British journal of clinical pharmacology, 80(2), 285-293 (2015-02-18)
A pilot study of add-on oral hypoglycemic agents in treatment-naïve genotype-1 chronic hepatitis C patients receiving peginterferon alfa-2b plus ribavirin.Ching-Sheng Hsu et al.Journal of the Formosan Medical Association = Taiwan yi zhi, 113(10), 716-721 (2014-06-30)
Efficacy of pegylated interferon and ribavirin combination therapy for patients with hepatitis C virus infection after curative resection or ablation for hepatocellular carcinoma--A retrospective multicenter study.Naoki Harada et al.Journal of medical virology, 87(7), 1199-1206 (2015-03-17)
Statin therapy improves response to interferon alfa and ribavirin in chronic hepatitis C: a systematic review and meta-analysis.Qianqian Zhu et al.Antiviral research, 98(3), 373-379 (2013-04-23)
Update on combinations of DAAs with and without pegylated-interferon and ribavirin: triple and quadruple therapy more than doubles SVR.Valérie Martel-Laferrière et al.Clinics in liver disease, 17(1), 93-103 (2012-11-28)
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Efficacy of sofosbuvir plus ribavirin with or without peginterferon-alfa in patients with hepatitis C virus genotype 3 infection and treatment-experienced patients with cirrhosis and hepatitis C virus genotype 2 infection.Graham R Foster et al.Gastroenterology, 149(6), 1462-1470 (2015-08-08)
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Attenuation of human enterovirus 71 high-replication-fidelity variants in AG129 mice.Tao Meng et al.Journal of virology, 88(10), 5803-5815 (2014-03-14)
Sofosbuvir and ribavirin prevent recurrence of HCV infection after liver transplantation: an open-label study.Michael P Curry et al.Gastroenterology, 148(1), 100-107 (2014-09-28)
High content image-based screening of a protease inhibitor library reveals compounds broadly active against Rift Valley fever virus and other highly pathogenic RNA viruses.Rajini Mudhasani et al.PLoS neglected tropical diseases, 8(8), e3095-e3095 (2014-08-22)
Retreatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin.Stefan Zeuzem et al.The New England journal of medicine, 370(17), 1604-1614 (2014-04-12)
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Association of interleukin-10 polymorphisms with chronic hepatitis C virus infection in a case-control study and its effect on the response to combined pegylated interferon/ribavirin therapy.A J Khan et al.Epidemiology and infection, 143(1), 71-80 (2014-03-20)
Genetic and pharmacologic inhibition of eIF4E reduces breast cancer cell migration, invasion, and metastasis.Filippa Pettersson et al.Cancer research, 75(6), 1102-1112 (2015-01-23)
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In vitro anti-influenza virus activities of a new lignan glycoside from the latex of Calotropis gigantea.Supawadee Parhira et al.PloS one, 9(8), e104544-e104544 (2014-08-08)
HCV-specific CD8+ cell detection at week 12 of chronic hepatitis C treatment with PEG-interferon-α2b/ribavirin correlates with infection resolution.Juan-Ramón Larrubia et al.Cellular immunology, 286(1-2), 31-38 (2013-11-30)
Secondary hyperpigmentation during interferon alfa treatment for chronic hepatitis C virus infection.Katerina Tsilika et al.JAMA dermatology, 149(6), 675-677 (2013-04-05)
OPERA: use of pegylated interferon plus ribavirin for treating HCV-HIV coinfection in interferon-naive patients.Giampiero Carosi et al.Antiviral therapy, 19(8), 735-745 (2014-03-04)
Novel Arenavirus Entry Inhibitors Discovered by Using a Minigenome Rescue System for High-Throughput Drug Screening.Jessica Y Rathbun et al.Journal of virology, 89(16), 8428-8443 (2015-06-05)
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Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques.Darryl Falzarano et al.Nature medicine, 19(10), 1313-1317 (2013-09-10)
Antiviral and antitumor activities of the lectin extracted from Aspidistra elatior.Xiao-Chao Xu et al.Zeitschrift fur Naturforschung. C, Journal of biosciences, 70(1-2), 7-13 (2015-04-10)
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[HCV reinfection after liver transplantation - management and first experiences with telaprevir-based triple therapy].K Herzer et al.Deutsche medizinische Wochenschrift (1946), 138(36), 1759-1764 (2013-09-05)
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Antiviral activity of Paulownia tomentosa against enterovirus 71 of hand, foot, and mouth disease.Ping Ji et al.Biological & pharmaceutical bulletin, 38(1), 1-6 (2015-03-07)
[Therapy of chronic hepatitis C].Stella Schaffstein et al.Praxis, 103(8), 423-436 (2014-04-10)
Association of interleukin-10 polymorphisms with chronic hepatitis C virus infection in a case-control study and its effect on the response to combined pegylated interferon/ribavirin therapy.A J Khan et al.Epidemiology and infection, 143(1), 71-80 (2014-03-20)
Sofosbuvir and ribavirin prevent recurrence of HCV infection after liver transplantation: an open-label study.Michael P Curry et al.Gastroenterology, 148(1), 100-107 (2014-09-28)
Preclinical evaluation of GS-9160, a novel inhibitor of human immunodeficiency virus type 1 integrase.Gregg S Jones et al.Antimicrobial agents and chemotherapy, 53(3), 1194-1203 (2008-12-24)
Ribavirin with interferon for hepatitis C in dialysis patients: efficacious and safe in the right patients in good hands.David Mutimer Gut, 64(2), 190-191 (2014-05-28)
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Pharmacokinetics and pharmacodynamics of setrobuvir, an orally administered hepatitis C virus non-nucleoside analogue inhibitor.Navita L Mallalieu et al.Clinical therapeutics, 36(12), 2047-2063 (2014-12-03)
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A non-interventional phase IV Belgian survey to assess the antiviral effectiveness of pegylated interferon-alpha-2b and ribavirin treatment according to the stage of liver fibrosis in previously untreated patients with genotype 1/4/5/6 chronic hepatitis C (PRACTICE).S Bourgeois et al.Acta gastro-enterologica Belgica, 77(4), 393-400 (2015-02-17)
Ischemic colitis during interferon-ribavirin therapy for chronic hepatitis C: a case report.Su Jung Baik et al.World journal of gastroenterology, 18(31), 4233-4236 (2012-08-25)
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Practical silyl protection of ribonucleosides.Thomas P Blaisdell et al.Organic letters, 15(18), 4710-4713 (2013-09-05)
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Development of biodegradable nanoparticles for liver-specific ribavirin delivery.Tsutomu Ishihara et al.Journal of pharmaceutical sciences, 103(12), 4005-4011 (2014-10-23)
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