没有数据	没有数据

没有数据	没有数据

来源	SDS样本
没有数据	没有数据

产品合成路线

更多

名称	CAS号

更多

文章

同行评议文献

FRET-Based Sorting of Live Cells Reveals Shifted Balance between PLK1 and CDK1 Activities During Checkpoint Recovery.Lorenzo Lafranchi et al.Cells, 9(9) (2020-09-24) Cryoelectron Tomography Reveals Nanoscale Organization of the Cytoskeleton and Its Relation to Microtubule Curvature Inside Cells.Saikat Chakraborty et al.Structure (London, England : 1993), 28(9), 991-1003 (2020-06-25) Kinesin-5 motors are required for organization of spindle microtubules in Silvetia compressa zygotes.Nick T Peters et al.BMC plant biology, 6, 19-19 (2006-09-02) Haploid genetic screens identify genetic vulnerabilities to microtubule-targeting agents.Nora M Gerhards et al.Molecular oncology, 12(6), 953-971 (2018-04-25) An allosteric transition trapped in an intermediate state of a new kinesin-inhibitor complex.Hung Yi Kristal Kaan et al.The Biochemical journal, 425(1), 55-60 (2009-10-02) Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5.Salvatore Debonis et al.Journal of medicinal chemistry, 51(5), 1115-1125 (2008-02-13) The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation.Linda Smith et al.Scientific reports, 7(1), 16115-16115 (2017-11-25) Microtubule interfering agents and KSP inhibitors induce the phosphorylation of the nuclear protein p54(nrb), an event linked to G2/M arrest.Pedro Casado et al.Journal of proteomics, 71(6), 592-600 (2008-10-04) Induction of a Spindle-Assembly-Competent M Phase in Xenopus Egg Extracts.Jitender S Bisht et al.Current biology : CB, 29(8), 1273-1285 (2019-04-02) EGF-induced centrosome separation promotes mitotic progression and cell survival.Balca R Mardin et al.Developmental cell, 25(3), 229-240 (2013-05-07) Tension-Induced Error Correction and Not Kinetochore Attachment Status Activates the SAC in an Aurora-B/C-Dependent Manner in Oocytes.Antoine Vallot et al.Current biology : CB, 28(1), 130-139 (2017-12-26) N-Decyl-S-trityl-(R)-cysteine, a new chiral selector for "green" ligand-exchange chromatography applications.Andrea Carotti et al.Journal of pharmaceutical and biomedical analysis, 144, 31-40 (2017-02-18) Effects of chemical manipulation of mitotic arrest and slippage on cancer cell survival and proliferation.Jenna L Riffell et al.Cell cycle (Georgetown, Tex.), 8(18), 3025-3038 (2009-08-29) Microtubule Sliding within the Bridging Fiber Pushes Kinetochore Fibers Apart to Segregate Chromosomes.Kruno Vukušić et al.Developmental cell, 43(1), 11-23 (2017-10-11) Dynamics of Human Telomerase Holoenzyme Assembly and Subunit Exchange across the Cell Cycle.Jacob M Vogan et al.The Journal of biological chemistry, 290(35), 21320-21335 (2015-07-15) Mechanical control of mitotic progression in single animal cells.Cedric J Cattin et al.Proceedings of the National Academy of Sciences of the United States of America, 112(36), 11258-11263 (2015-08-26) Proteomic analysis of annexin A2 phosphorylation induced by microtubule interfering agents and kinesin spindle protein inhibitors.Belen Fernandez-Garcia et al.Journal of proteome research, 9(9), 4649-4660 (2010-07-06) A direct interaction between survivin and myosin II is required for cytokinesis.Aryeh Babkoff et al.Journal of cell science, 132(14) (2019-07-19) Loop 5-directed compounds inhibit chimeric kinesin-5 motors: implications for conserved allosteric mechanisms.Liqiong Liu et al.The Journal of biological chemistry, 286(8), 6201-6210 (2010-12-04) Docetaxel-resistant prostate cancer cells remain sensitive to S-trityl-L-cysteine-mediated Eg5 inhibition.Carolyn Wiltshire et al.Molecular cancer therapeutics, 9(6), 1730-1739 (2010-06-03) Quiescent Cells Actively Replenish CENP-A Nucleosomes to Maintain Centromere Identity and Proliferative Potential.S Zachary Swartz et al.Developmental cell, 51(1), 35-48 (2019-08-20) CLIC4 and CLIC1 bridge plasma membrane and cortical actin network for a successful cytokinesis.Zeynep Cansu Uretmen Kagiali et al.Life science alliance, 3(2) (2019-12-28) Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation.Helen J Whalley et al.Nature communications, 6, 7437-7437 (2015-06-17) The balance between KIFC3 and EG5 tetrameric kinesins controls the onset of mitotic spindle assembly.Shoji Hata et al.Nature cell biology, 21(9), 1138-1151 (2019-09-05) Activation of the oncogenic transcription factor B-Myb via multisite phosphorylation and prolyl cis/trans isomerization.Eugen Werwein et al.Nucleic acids research, 47(1), 103-121 (2018-10-16) DnaJB6 is a RanGTP-regulated protein required for microtubule organization during mitosis.Miquel Rosas-Salvans et al.Journal of cell science, 132(11) (2019-05-09) Inhibition of hepatitis C virus NS5B polymerase by S-trityl-L-cysteine derivatives.Daniel B Nichols et al.European journal of medicinal chemistry, 49, 191-199 (2012-01-28) The 3D Topography of Mitotic Chromosomes.Lingluo Chu et al.Molecular cell, 79(6), 902-916 (2020-08-10) Cysteine-S-trityl a key derivative to prepare N-methyl cysteines.Eleonora Marcucci et al.Journal of combinatorial chemistry, 10(1), 69-78 (2007-11-21) Estrogen-dependent regulation of Eg5 in breast cancer cells.Maricarmen D Planas-Silva et al.Anti-cancer drugs, 18(7), 773-779 (2007-06-22) S-trityl-L-cysteine derivative induces caspase-independent cell death in K562 human chronic myeloid leukemia cell line.Makiko Shimizu et al.Cancer letters, 298(1), 99-106 (2010-07-14) Optimized S-trityl-L-cysteine-based inhibitors of kinesin spindle protein with potent in vivo antitumor activity in lung cancer xenograft models.James A D Good et al.Journal of medicinal chemistry, 56(5), 1878-1893 (2013-02-12) Microtubule End-Clustering Maintains a Steady-State Spindle Shape.Christina L Hueschen et al.Current biology : CB, 29(4), 700-708 (2019-02-13) Environmental stresses induce karyotypic instability in colorectal cancer cells.Zhihao Tan et al.Molecular biology of the cell, 30(1), 42-55 (2018-11-01) Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines.Marion A A Libouban et al.Oncotarget, 8(24), 38309-38325 (2017-04-19) Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding.Yusuke Toyoda et al.Nature communications, 8(1), 1266-1266 (2017-11-04) An Attachment-Independent Biochemical Timer of the Spindle Assembly Checkpoint.Junbin Qian et al.Molecular cell, 68(4), 715-730 (2017-11-14) The conserved L5 loop establishes the pre-powerstroke conformation of the Kinesin-5 motor, eg5.Adam G Larson et al.Biophysical journal, 98(11), 2619-2627 (2010-06-02) PLK1 plays dual roles in centralspindlin regulation during cytokinesis.Ingrid E Adriaans et al.The Journal of cell biology, 218(4), 1250-1264 (2019-02-08) AURKA destruction is decoupled from its activity at mitotic exit but is essential to suppress interphase activity.Ahmed Abdelbaki et al.Journal of cell science, 133(12) (2020-05-13) Binding partner switching on microtubules and aurora-B in the mitosis to cytokinesis transition.Nurhan Ozlü et al.Molecular & cellular proteomics : MCP, 9(2), 336-350 (2009-09-30) High resolution quantitative proteomics of HeLa cells protein species using stable isotope labeling with amino acids in cell culture(SILAC), two-dimensional gel electrophoresis(2DE) and nano-liquid chromatograpohy coupled to an LTQ-OrbitrapMass spectrometer.Bernd Thiede et al.Molecular & cellular proteomics : MCP, 12(2), 529-538 (2012-10-04) Biochemical analysis of cellular target of S-trityl-L-cysteine derivatives using affinity matrix.Makiko Shimizu et al.Bioorganic & medicinal chemistry letters, 20(5), 1578-1580 (2010-02-09) Nuclear envelope deformation controls cell cycle progression in response to mechanical force.Julien Aureille et al.EMBO reports, 20(9), e48084-e48084 (2019-08-02) The balance of forces generated by kinesins controls spindle polarity and chromosomal heterogeneity in tetraploid cells.Sei Shu et al.Journal of cell science, 132(24) (2019-11-24) Proteome analysis of apoptosis signaling by S-trityl-L-cysteine, a potent reversible inhibitor of human mitotic kinesin Eg5.Frank Kozielski et al.Proteomics, 8(2), 289-300 (2008-01-11) HSP70 regulates Eg5 distribution within the mitotic spindle and modulates the cytotoxicity of Eg5 inhibitors.Chieh-Ting Fang et al.Cell death & disease, 11(8), 715-715 (2020-09-03) Doing the methylene shuffle--further insights into the inhibition of mitotic kinesin Eg5 with S-trityl L-cysteine.Murad N Abualhasan et al.European journal of medicinal chemistry, 54, 483-498 (2012-07-04) Molecular dissection of the inhibitor binding pocket of mitotic kinesin Eg5 reveals mutants that confer resistance to antimitotic agents.Sébastien Brier et al.Journal of molecular biology, 360(2), 360-376 (2006-06-20) IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning.Nicolas Taulet et al.Nature communications, 8(1), 1928-1928 (2017-12-06) Binding Dynamics of α-Actinin-4 in Dependence of Actin Cortex Tension.Kamran Hosseini et al.Biophysical journal, 119(6), 1091-1107 (2020-08-28) PP2A--B55γ counteracts Cdk1 and regulates proper spindle orientation through the cortical dynein adaptor NuMA.Riya Keshri et al.Journal of cell science, 133(14) (2020-06-28) Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase.Erik Müllers et al.Cell cycle (Georgetown, Tex.), 13(17), 2733-2743 (2014-12-09) Multivalent Interactions of Polyamide Based Sequence-Controlled Glycomacromolecules with Concanavalin A.Alberto Camaleño de la Calle et al.Macromolecular bioscience, 19(6), e1900033-e1900033 (2019-04-13) Isobaric peptide termini labeling utilizing site-specific N-terminal succinylation.Christian J Koehler et al.Analytical chemistry, 83(12), 4775-4781 (2011-05-03) Xenopus oocyte meiosis lacks spindle assembly checkpoint control.Hua Shao et al.The Journal of cell biology, 201(2), 191-200 (2013-04-10) The Fcp1-Wee1-Cdk1 axis affects spindle assembly checkpoint robustness and sensitivity to antimicrotubule cancer drugs.R Visconti et al.Cell death and differentiation, 22(9), 1551-1560 (2015-03-07) The Poisson Ratio of the Cellular Actin Cortex Is Frequency Dependent.Marcel Mokbel et al.Biophysical journal, 118(8), 1968-1976 (2020-03-26) Mutations in the human kinesin Eg5 that confer resistance to monastrol and S-trityl-L-cysteine in tumor derived cell lines.Sergey Tcherniuk et al.Biochemical pharmacology, 79(6), 864-872 (2009-11-10) Inner centromere localization of the CPC maintains centromere cohesion and allows mitotic checkpoint silencing.Rutger C C Hengeveld et al.Nature communications, 8, 15542-15542 (2017-06-01)

备注