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2-Chlorocyclohexanone | CAS:822-87-7
2-Chlorocyclohexanone
  • 名称:2-氯环己酮 | 2-Chlorocyclohexanone
  • CAS号:822-87-7
  • 别名:
  • 分子式:C6H9ClO
  • 分子量:132.59
  • EINESC号:212-505-5

产品描述

物理化学性质

熔点 23 ºC
沸点 82-83 ºC (10 mmHg)
闪点 82 ºC
密度 1.161
折射率 1.483-1.485

安全数据

危险品标志 Xi
危险类别码 R36/37/38
安全说明书 S26;S37/39

SDS

来源 SDS样本
Alfa-Aesar 浏览或下载
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[Effect of polysaccharides from Radix Glycyrrhizae on migration and polyamines contents of IEC-6 cell].Peng Wen et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(7), 1112-1116 (2012-12-21) Trypanosoma brucei eflornithine transporter AAT6 is a low-affinity low-selective transporter for neutral amino acids.Christoph Mathieu et al.The Biochemical journal, 463(1), 9-18 (2014-07-06) Anticarcinogenic activity of alpha-difluoromethylornithine, ginseng, eleutherococcus, and leuzea on radiation-induced carcinogenesis in female rats.Vladimir G Bespalov et al.International journal of radiation biology, 90(12), 1191-1200 (2014-06-11) Combination chemoprevention: future direction of colorectal cancer prevention.Ping Zhou et al.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 21(3), 231-240 (2012-03-30) A phase III skin cancer chemoprevention study of DFMO: long-term follow-up of skin cancer events and toxicity.Sarah M Kreul et al.Cancer prevention research (Philadelphia, Pa.), 5(12), 1368-1374 (2012-10-13) Mathematical modelling of polyamine metabolism in bloodstream-form Trypanosoma brucei: an application to drug target identification.Xu Gu et al.PloS one, 8(1), e53734-e53734 (2013-02-02) Difluoromethylornithine: the proof is in the polyamines.Joanne M Jeter et al.Cancer prevention research (Philadelphia, Pa.), 5(12), 1341-1344 (2012-12-12) [Comparative effects of difluoromethylornithine and tincture of Siberian ginseng root on radiation carcinogenesis and life span in rats].V G Bespalov et al.Advances in gerontology = Uspekhi gerontologii, 25(2), 293-300 (2012-11-08) In-hospital safety in field conditions of nifurtimox eflornithine combination therapy (NECT) for T. b. gambiense sleeping sickness.Caecilia Schmid et al.PLoS neglected tropical diseases, 6(11), e1920-e1920 (2012-12-05) Structural insight into DFMO resistant ornithine decarboxylase from Entamoeba histolytica: an inkling to adaptive evolution.Preeti et al.PloS one, 8(1), e53397-e53397 (2013-01-18) Difluoromethylornithine: the proof is in the polyamines.Joanne M Jeter et al.Cancer prevention research (Philadelphia, Pa.), 5(12), 1341-1344 (2012-12-12) Reversal of difluoromethylornithine effects by the administration of putrescine in rats.Rehana Rehman et al.JPMA. The Journal of the Pakistan Medical Association, 61(8), 752-755 (2012-02-24) Role of obesity in a randomized placebo-controlled trial of difluoromethylornithine (DFMO) + sulindac for the prevention of sporadic colorectal adenomas.Jason A Zell et al.Cancer causes & control : CCC, 23(10), 1739-1744 (2012-08-22) Do we need new drugs against human African trypanosomiasis?August Stich et al.The Lancet. Infectious diseases, 13(9), 733-734 (2013-08-24) Spermidine Exhibits Protective Effects Against Traumatic Brain Injury.Jianxing Huang et al.Cellular and molecular neurobiology, 40(6), 927-937 (2020-01-10) Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression.Yubin Guo et al.Nature communications, 11(1), 3243-3243 (2020-06-28) Arginase enzymes in the human prostate: expression of arginase isoenzymes and effects of arginase inhibitors on isolated human prostate tissue.George T Kedia et al.BJU international, 110(11 Pt C), E1196-E1201 (2012-09-29) [Pharmaco and diet based prostate cancer prevention].François Eisinger et al.Bulletin du cancer, 100(5), 497-507 (2013-05-23) AMXT-1501, a novel polyamine transport inhibitor, synergizes with DFMO in inhibiting neuroblastoma cell proliferation by targeting both ornithine decarboxylase and polyamine transport.Katherine Samal et al.International journal of cancer, 133(6), 1323-1333 (2013-03-05) Identification of gp120 binding sites on CXCR4 by using CD4-independent human immunodeficiency virus type 2 Env proteins.George Lin et al.Journal of virology, 77(2), 931-942 (2002-12-28) Patient-Specific Retinal Organoids Recapitulate Disease Features of Late-Onset Retinitis Pigmentosa.Mei-Ling Gao et al.Frontiers in cell and developmental biology, 8, 128-128 (2020-03-27) Suppression of LFA-1 expression by spermine is associated with enhanced methylation of ITGAL, the LFA-1 promoter area.Yoshihiko Kano et al.PloS one, 8(2), e56056-e56056 (2013-02-19) DFMO/eflornithine inhibits migration and invasion downstream of MYCN and involves p27Kip1 activity in neuroblastoma.Dana-Lynn T Koomoa et al.International journal of oncology, 42(4), 1219-1228 (2013-02-27) Polyamines inhibit the assembly of stress granules in normal intestinal epithelial cells regulating apoptosis.Tongtong Zou et al.American journal of physiology. Cell physiology, 303(1), C102-C111 (2012-05-05) Functional roles of arginine during the peri-implantation period of pregnancy. III. Arginine stimulates proliferation and interferon tau production by ovine trophectoderm cells via nitric oxide and polyamine-TSC2-MTOR signaling pathwaysWang X, et al. Biology of Reproduction, 92(3), 75-71 (2015) Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma.Michelle L North et al.American journal of respiratory cell and molecular biology, 48(6), 694-702 (2013-03-09) ATP13A2 deficiency disrupts lysosomal polyamine export.Sarah van Veen et al.Nature, 578(7795), 419-424 (2020-01-31) Effects of BPA on expression of apoptotic genes and migration of ovine trophectoderm (oTr1) cells during the peri-implantation period of pregnancyElmetwally MA, et al. Reproductive Toxicology, 83, 73-79 (2019) Clinical end points for developing pharmaceuticals to manage patients with a sporadic or genetic risk of colorectal cancer.Nathaniel S Rial et al.Expert review of gastroenterology & hepatology, 6(4), 507-517 (2012-08-30) The investigation and management of hirsutism.Stephen Franks The journal of family planning and reproductive health care, 38(3), 182-186 (2012-07-13) Effects of BPA on expression of apoptotic genes and migration of ovine trophectoderm (oTr1) cells during the peri-implantation period of pregnancy.Mohammed A Elmetwally et al.Reproductive toxicology (Elmsford, N.Y.), 83, 73-79 (2018-12-12) Fumarate hydratase-deficient renal cell carcinoma cells respond to asparagine by activation of the unfolded protein response and stimulation of the hexosamine biosynthetic pathway.Rony Panarsky et al.Cancer & metabolism, 8, 7-7 (2020-08-11) Development of difluoromethylornithine (DFMO) as a chemoprevention agentMeyskens FL and Gerner EW Clinical Cancer Research, 5(5), 945-951 (1999) Polyamine inhibitors for treatment of feline oral squamous cell carcinoma: a proof-of-concept study.John R Lewis et al.Journal of veterinary dentistry, 30(3), 140-145 (2014-01-01) Alpha-difluoromethylornithine, an irreversible inhibitor of polyamine biosynthesis, as a therapeutic strategy against hyperproliferative and infectious diseasesLoGiudice N, et al. Medical sciences (Basel, Switzerland), 6(1), 12-12 (2018) Topical treatment with diclofenac, calcipotriol (vitamin-D3 analog) and difluoromethylornithine (DFMO) does not prevent nonmelanoma skin cancer in mice.H C Pommergaard et al.Cancer investigation, 31(2), 92-96 (2013-02-01) Nifurtimox-eflornithine combination therapy for second-stage gambiense human African trypanosomiasis: Médecins Sans Frontières experience in the Democratic Republic of the Congo.Emilie Alirol et al.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 56(2), 195-203 (2012-10-18) Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against Trypanosoma brucei.Isabel M Vincent et al.PLoS neglected tropical diseases, 6(5), e1618-e1618 (2012-05-09) Ribonuclease activity of p53 in cytoplasm in response to various stress signals.Sanaz Derech-Haim et al.Cell cycle (Georgetown, Tex.), 11(7), 1400-1413 (2012-03-17) [Identification of the functional activity of synthetic polyamine analogues using a biotest system based on highly proliferating cultured human cells].K V Lisitskaia et al.Prikladnaia biokhimiia i mikrobiologiia, 49(2), 124-128 (2013-06-26) Arginine enhances embryo implantation in rats through PI3K/PKB/mTOR/NO signaling pathway during early pregnancy.Xiangfang Zeng et al.Reproduction (Cambridge, England), 145(1), 1-7 (2012-10-20)
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