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A new use for an old drug: carmofur attenuates lipopolysaccharides (LPS) induced acute lung injury via inhibition of FAAH and NAAA activitiesLi Y, et al. Frontiers in Pharmacology, 10(6), 818-818 (2019) Screening a Commercial Library of Pharmacologically Active Small Molecules against Staphylococcus aureus Biofilms.Nelson S Torres et al.Antimicrobial agents and chemotherapy, 60(10), 5663-5672 (2016-07-13) Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofurJin Z, et al. Nature Structural and Molecular Biology, 27(6), 529-532 (2020) [Report on an autopsy of a cancer patient with Carmofur (HCFU) leukoencephalopathy].A Furuya et al.Rinsho shinkeigaku = Clinical neurology, 27(11), 1430-1440 (1987-11-01) [Adjuvant chemotherapy for colorectal cancer].Takayuki Akasu Gan to kagaku ryoho. Cancer & chemotherapy, 33(3), 307-312 (2006-03-15) Hyperphosphorylated tau aggregation and cytotoxicity modulators screen identified prescription drugs linked to Alzheimer's disease and cognitive functions.Mengyu Liu et al.Scientific reports, 10(1), 16551-16551 (2020-10-08) Molecular Targeting of Acid Ceramidase in Glioblastoma: A Review of Its Role, Potential Treatment, and Challenges.Ha S Nguyen et al.Pharmaceutics, 10(2) (2018-04-13) Electrosprayed Janus Particles for Combined Photo-Chemotherapy.Brenda Sanchez-Vazquez et al.AAPS PharmSciTech, 18(5), 1460-1468 (2016-10-04) [Appropriate duration of postoperative oral adjuvant chemotherapy with HCFU for colorectal cancer].Kiyotaka Ito et al.Gan to kagaku ryoho. Cancer & chemotherapy, 31(1), 55-59 (2004-01-31) [Multicenter comparative study of the recurrence-inhibitory effect of oral fluoropyrimidine drugs in patients with colorectal cancer following curative resection].Sotaro Sadahiro et al.Gan to kagaku ryoho. Cancer & chemotherapy, 32(7), 997-1005 (2005-07-28) Leukoencephalopathy following treatment with carmofur: a case report and review of the Japanese literature.T Yamada et al.Asia-Oceania journal of obstetrics and gynaecology, 15(2), 161-168 (1989-06-01) Lysosomal glycosphingolipid catabolism by acid ceramidase: formation of glycosphingoid bases during deficiency of glycosidases.Maria J Ferraz et al.FEBS letters, 590(6), 716-725 (2016-02-24) Acid ceramidase inhibition ameliorates α-synuclein accumulation upon loss of GBA1 function.Myung Jong Kim et al.Human molecular genetics, 27(11), 1972-1988 (2018-03-27) Lysosomal glycosphingolipid catabolism by acid ceramidase: formation of glycosphingoid bases during deficiency of glycosidasesFerraz M J, et al. Febs Letters, 590(6), 716-725 (2016) An individual patient data meta-analysis of adjuvant therapy with carmofur in patients with curatively resected colon cancer.Junichi Sakamoto et al.Japanese journal of clinical oncology, 35(9), 536-544 (2005-09-13) Exchange of polar lipids from adults to neonates in Daphnia magna: Perturbations in sphingomyelin allocation by dietary lipids and environmental toxicants.Namrata Sengupta et al.PloS one, 12(5), e0178131-e0178131 (2017-05-26) Randomized controlled trial of the efficacy of adjuvant immunochemotherapy and adjuvant chemotherapy for colorectal cancer, using different combinations of the intracutaneous streptococcal preparation OK-432 and the oral pyrimidines 1-hexylcarbamoyl-5-fluorouracil and uracil/tegafur.Masahiko Watanabe et al.International journal of clinical oncology, 9(2), 98-106 (2004-04-27) A New Use for an Old Drug: Carmofur Attenuates Lipopolysaccharide (LPS)-Induced Acute Lung Injury via Inhibition of FAAH and NAAA Activities.Kangni Wu et al.Frontiers in pharmacology, 10, 818-818 (2019-08-06) Subacute leucoencephalopathy induced by carmofur, a 5-fluorouracil derivative.S Kuzuhara et al.Journal of neurology, 234(6), 365-370 (1987-08-01) Post-operative adjuvant chemotherapy for colorectal cancer with 5-fluorouracil (5-FU) infusion combined with 1-hexylcarbamoyl-5-fluorouracil (HCFU) oral administration after curative resection.H Iwagaki et al.Anticancer research, 21(6A), 4163-4168 (2002-03-26) Molecular targeting of acid ceramidase in glioblastoma: a review of its role, potential treatment, and challengesNguyen H S, et al. Pharmaceutics, 10(2), 45-45 (2018) Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa.Yael Pewzner-Jung et al.EMBO molecular medicine, 6(9), 1205-1214 (2014-08-03) Efficacy of oral adjuvant therapy after resection of colorectal cancer: 5-year results from three randomized trials.Junichi Sakamoto et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 22(3), 484-492 (2004-01-31) 1-hexylcarbamoyl-5-fluorouracil + cyclophosphamide + tamoxifen versus CMF + tamoxifen in women with lymph node-positive breast cancer after primary surgery: a randomized controlled trial.Takeshi Tominaga et al.Oncology reports, 12(4), 797-803 (2004-09-18) Raltitrexed treatment promotes systemic inflammatory reaction in patients with colorectal carcinoma.P Osterlund et al.British journal of cancer, 87(6), 591-599 (2002-09-19) Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur.Zhenming Jin et al.Nature structural & molecular biology, 27(6), 529-532 (2020-05-10) [Leukoencephalopathy caused by antineoplastic drugs].Tomohiko Mizutani Brain and nerve = Shinkei kenkyu no shinpo, 60(2), 137-141 (2008-03-01) S-1 (TS-1) maintained complete response for approximately 10 years in a case of metastatic breast cancer.Naruto Taira et al.Breast cancer (Tokyo, Japan), 13(2), 220-224 (2006-06-07) CEA fluctuation during a single fluorouracil-based chemotherapy cycle for metastatic colorectal cancer.Kethe Hermunen et al.Anticancer research, 33(1), 253-260 (2012-12-26) pH-Responsive nanocomposite fibres allowing MRI monitoring of drug release.Ziwei Zhang et al.Journal of materials chemistry. B, 8(32), 7264-7274 (2020-07-10) [Drug-induced leukoencephalopathy].Keiko Ota et al.Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 96(8), 1641-1645 (2007-09-07) Genetic ablation of acid ceramidase in Krabbe disease confirms the psychosine hypothesis and identifies a new therapeutic target.Yedda Li et al.Proceedings of the National Academy of Sciences of the United States of America, 116(40), 20097-20103 (2019-09-19) [Neo-adjuvant chemotherapy with carmofur for colorectal cancer--a multi-institutional randomized controlled study].Kenjiro Kotake et al.Gan to kagaku ryoho. Cancer & chemotherapy, 29(11), 1917-1924 (2002-12-06) [Analysis of microsatellite instability and p53 LOH in advanced colorectal cancers--first report of the No. 3 protocol].Naohiro Tomita et al.Gan to kagaku ryoho. Cancer & chemotherapy, 31(3), 367-372 (2004-03-30) A multicenter randomized study comparing 5-fluorouracil continuous infusion (ci) plus 1-hexylcarbamoyl-5-fluorouracil and 5-FU ci alone in colorectal cancer.Kenjiro Kotake et al.Oncology reports, 14(1), 129-134 (2005-06-10) Delivery of hydrophobised 5-fluorouracil derivative to brain tissue through intravenous route using surface modified nanogels.Sheetal Soni et al.Journal of drug targeting, 14(2), 87-95 (2006-04-13) Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity.Natalia Realini et al.Scientific reports, 3, 1035-1035 (2013-01-10) Co-polymeric hydrophilic nanospheres for drug delivery: release kinetics, and cellular uptake.Anita Kamra Verma et al.Indian journal of experimental biology, 48(10), 1043-1052 (2011-02-09) [Drug-induced leukoencephalopathy].Tomohiko Mizutani Nihon rinsho. Japanese journal of clinical medicine, 65 Suppl 8, 372-376 (2007-12-13) Immunochemotherapy with PSK and fluoropyrimidines improves long-term prognosis for curatively resected colorectal cancer.Toshimi Sakai et al.Cancer biotherapy & radiopharmaceuticals, 23(4), 461-467 (2008-09-06) Postoperative adjuvant use of carmofur for early breast cancer.Ken Morimoto et al.Osaka city medical journal, 49(2), 77-83 (2004-06-08)

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