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A study on the pharmacokinetics of chlorzoxazone in healthy Thai volunteers.Nantaporn Prompila et al.Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 90(1), 160-166 (2007-07-12) Phenobarbital induces monkey brain CYP2E1 protein but not hepatic CYP2E1, in vitro or in vivo chlorzoxazone metabolism.Anna M Lee et al.European journal of pharmacology, 552(1-3), 151-158 (2006-10-20) Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes.Bent H Hellum et al.Basic & clinical pharmacology & toxicology, 105(1), 58-63 (2009-04-18) In vivo CYP2E1 phenotyping as a new potential biomarker of occupational and experimental exposure to benzene.P Piccoli et al.Toxicology letters, 192(1), 29-33 (2009-11-11) In vitro Inhibitory Effects of Cynaroside on Human Liver Cytochrome P450 Enzymes.Lei Wang et al.Pharmacology, 104(5-6), 296-302 (2019-10-07) No effect on pharmacokinetics of tamoxifen and 4-hydroxytamoxifen by multiple doses of red clover capsule in rats.Kanumuri Siva Rama Raju et al.Scientific reports, 5, 16126-16126 (2015-11-05) Effects of recombinant human growth hormone on the pharmacokinetics of intravenous chlorzoxazone in rats with acute renal failure induced by uranyl nitrate.Won- Suk Chung et al.Life sciences, 73(3), 253-263 (2003-05-22) Development of an in vitro cytochrome P450 cocktail inhibition assay for assessing the inhibition risk of drugs of abuse.Julia Dinger et al.Toxicology letters, 230(1), 28-35 (2014-08-12) Time-dependent effects of Klebsiella pneumoniae endotoxin on the pharmacokinetics of chlorzoxazone and its main metabolite, 6-hydroxychlorzoxazone, in rats: restoration of the parameters in 96 hour in KPLPS rats to control levels.Hye Y Jung et al.Biopharmaceutics & drug disposition, 30(8), 485-493 (2009-09-16) Different mechanisms of handling ingested polycyclic aromatic hydrocarbons in mammalian species: organ-specific response patterns of CYP1A1-induction after oral intake of PAH-contaminated soils.P H Roos et al.Xenobiotica; the fate of foreign compounds in biological systems, 34(9), 781-795 (2005-03-04) Yang Li et al.Pharmaceutical biology, 58(1), 695-700 (2020-07-17)Lysionotin, a major extraction of Lysionotus pauciflorus Maxim (Gesneriaceae), has a variety of pharmacological properties commonly used in the treatment of lung disease. A study of lysionotin on the activity of human liver cytochrome P450 (CYP) enzymes can provide guidance... Delamanid does not inhibit or induce cytochrome p450 enzymes in vitro.Yoshihiko Shimokawa et al.Biological & pharmaceutical bulletin, 37(11), 1727-1735 (2014-11-05) Pharmacokinetics of intravenous chlorzoxazone in rats with dehydration and rehydration: effects of food intakes.Yu C Kim et al.Biopharmaceutics & drug disposition, 24(2), 53-61 (2003-03-06) Comparison of liquid chromatography and supercritical fluid chromatography coupled to compact single quadrupole mass spectrometer for targeted in vitro metabolism assay.Dany Spaggiari et al.Journal of chromatography. A, 1371, 244-256 (2014-12-03) Deleterious effects induced by oxidative stress in liver nuclei from rats receiving an alcohol-containing liquid diet.M I Díaz Gómez et al.Toxicology and industrial health, 24(10), 625-634 (2009-01-15) Study of the fragmentation mechanism of protonated 6-hydroxychlorzoxazone: application in simultaneous analysis of CYP2E1 activity with major human cytochrome P450s.M Reza Anari et al.Analytical chemistry, 75(3), 469-478 (2003-02-15) Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration.Yiming Jiang et al.Toxicological sciences : an official journal of the Society of Toxicology, 143(1), 107-115 (2014-10-17) Inhibition of human cytochrome P450 enzymes by licochalcone A, a naturally occurring constituent of licorice.Wei He et al.Toxicology in vitro : an international journal published in association with BIBRA, 29(7), 1569-1576 (2015-06-24) Pharmacokinetic parameters of chlorzoxazone and its main metabolite, 6-hydroxychlorzoxazone, after intravenous and oral administration of chlorzoxazone to liver cirrhotic rats with diabetes mellitus.Choong Y Ahn et al.Drug metabolism and disposition: the biological fate of chemicals, 36(7), 1233-1241 (2008-04-02) Metabolic characterization of meso-dihydroguaiaretic acid in liver microsomes and in mice.Jang Su Jeon et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 76, 94-102 (2014-12-24) Determination of 6-hydroxychlorzoxazone and chlorzoxazone in porcine microsome samples.Sherry K Cox et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 784(1), 111-116 (2002-12-31) Expression and activity of the cytochrome P450 2E1 in patients with nonalcoholic steatosis and steatohepatitis.Haithem Chtioui et al.Liver international : official journal of the International Association for the Study of the Liver, 27(6), 764-771 (2007-07-10) Fennel and raspberry leaf as possible inhibitors of acetaminophen oxidation.Astrid Jordet Langhammer et al.Phytotherapy research : PTR, 28(10), 1573-1576 (2014-01-25) In vitro inhibitory effects of pristimerin on human liver cytochrome P450 enzymes.Xiaoyi Hao et al.Xenobiotica; the fate of foreign compounds in biological systems, 48(12), 1185-1191 (2017-04-08) In vitro inhibitory effects of dihydromyricetin on human liver cytochrome P450 enzymes.Lu Liu et al.Pharmaceutical biology, 55(1), 1868-1874 (2017-06-16) Inhibitory effect of Aristolochia fruit on Cytochrome P450 isozymes in vitro and in vivo.Shuzhen Zhu et al.Pakistan journal of pharmaceutical sciences, 28(3), 939-944 (2015-05-26) Phenotyping of cytochrome P450 2E1 in vitro and in vivo.Lena Ernstgård et al.Current drug metabolism, 8(5), 493-498 (2007-06-23) Hepato-protective effect of resveratrol against acetaminophen-induced liver injury is associated with inhibition of CYP-mediated bioactivation and regulation of SIRT1-p53 signaling pathways.Ying Wang et al.Toxicology letters, 236(2), 82-89 (2015-05-10) Severely Impaired and Dysregulated Cytochrome P450 Expression and Activities in Hepatocellular Carcinoma: Implications for Personalized Treatment in Patients.Tongmeng Yan et al.Molecular cancer therapeutics, 14(12), 2874-2886 (2015-10-31) CYP2E1 regulation by benzene and other small organic chemicals in rat liver and peripheral lymphocytes.Eva González-Jasso et al.Toxicology letters, 144(1), 55-67 (2003-08-16) Selective effects of nitric oxide on the disposition of chlorzoxazone and dextromethorphan in isolated perfused rat livers.Ragini Vuppugalla et al.Drug metabolism and disposition: the biological fate of chemicals, 34(7), 1160-1166 (2006-04-20) Wuzhi tablet (Schisandra Sphenanthera extract) protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of NRF2-ARE and p53/p21 pathways.Xiaomei Fan et al.Drug metabolism and disposition: the biological fate of chemicals, 42(12), 1982-1990 (2014-09-14) Interaction of selected platinum(II) complexes containing roscovitine-based CDK inhibitors as ligands with human liver microsomal cytochrome P450.Vlastimil Masek et al.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 159(3), 382-387 (2014-07-10) Hepatic disposition of the cytochrome P450 2E1 marker chlorzoxazone and its hydroxylated metabolite in isolated perfused rat livers.Reza Mehvar et al.Journal of pharmaceutical sciences, 95(7), 1414-1424 (2006-05-26) Impaired 6-hydroxychlorzoxazone elimination in patients with kidney disease: Implication for cytochrome P450 2E1 pharmacogenetic studies.Thomas D Nolin et al.Clinical pharmacology and therapeutics, 74(6), 555-568 (2003-12-10) Effect of high-dose aspirin on CYP2E1 activity in healthy subjects measured using chlorzoxazone as a probe.Ji-Young Park et al.Journal of clinical pharmacology, 46(1), 109-114 (2006-01-07) Evaluation of the in vitro/in vivo drug interaction potential of BST204, a purified dry extract of ginseng, and its four bioactive ginsenosides through cytochrome P450 inhibition/induction and UDP-glucuronosyltransferase inhibition.Yu Fen Zheng et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 68, 117-127 (2014-03-19) Inhibitory mechanisms of celastrol on human liver cytochrome P450 1A2, 2C19, 2D6, 2E1 and 3A4.Chunhuan Jin et al.Xenobiotica; the fate of foreign compounds in biological systems, 45(7), 571-577 (2015-03-27) Pharmacokinetics of chlorzoxazone in rats with diabetes: Induction of CYP2E1 on 6-hydroxychlorzoxazone formation.Hye W Baek et al.Journal of pharmaceutical sciences, 95(11), 2452-2462 (2006-08-04) Baodong Ding et al.Xenobiotica; the fate of foreign compounds in biological systems, 50(8), 913-918 (2020-02-07)Pachymic acid is a wildly used traditional Chinese medicine with various pharmacological features. It also exists in many drugs which are wildly used in pediatric.The effect of pachymic acid on the activity of eight major CYP isoforms was investigated in... Identification of the rat liver cytochrome P450 enzymes involved in the metabolism of the calcium channel blocker dipfluzine hydrochloride.Wei Guo et al.Environmental toxicology and pharmacology, 38(3), 901-912 (2014-12-03) In vitro inhibition of human CYP2D6 by the chiral pesticide fipronil and its metabolite fipronil sulfone: Prediction of pesticide-drug interactions.Daniel Blascke Carrão et al.Toxicology letters, 313, 196-204 (2019-07-07) Determination of brain cytochrome P450 2E1 activity in rat with the probe of chlorzoxazone by liquid chromatography-mass spectrometry.Jian-Yuan Wu et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(3-4), 260-266 (2011-01-05) Jingwei Zhang et al.Xenobiotica; the fate of foreign compounds in biological systems, 49(10), 1127-1132 (2018-04-21)1. Sophocarpine is a biologically active component isolated from the foxtail-like sophora herb and seed that is often orally administered for the treatment of cancer and chronic bronchial asthma. However, whether sophocarpine affects the activity of human liver cytochrome P450 (CYP)... Multifaceted interaction of the traditional Chinese medicinal herb Schisandra chinensis with cytochrome P450-mediated drug metabolism in rats.Baolian Wang et al.Journal of ethnopharmacology, 155(3), 1473-1482 (2014-08-06) Circadian rhythm of cytochrome P4502E1 and its effect on disposition kinetics of chlorzoxazone in rats.Phisit Khemawoot et al.European journal of pharmacology, 574(1), 71-76 (2007-07-27) Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation.Yiming Jiang et al.Chemico-biological interactions, 231, 83-89 (2015-03-11) Hepatic cytochrome P450 2E1 activity in nonalcoholic fatty liver disease.Nantaporn Prompila et al.Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 91(5), 733-738 (2008-08-05) Effects of acute renal failure on the pharmacokinetics of chlorzoxazone in rats.Young Jin Moon et al.Drug metabolism and disposition: the biological fate of chemicals, 31(6), 776-784 (2003-05-21) Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole.Shotaro Uehara et al.Drug metabolism and disposition: the biological fate of chemicals, 43(10), 1408-1416 (2015-08-01) Effect of commercially available green and black tea beverages on drug-metabolizing enzymes and oxidative stress in Wistar rats.Hsien-Tsung Yao et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 70, 120-127 (2014-05-13) Effects of steady-state lasofoxifene on CYP2D6- and CYP2E1-mediated metabolism.Robert A Moller et al.The Annals of pharmacotherapy, 40(1), 32-37 (2005-12-22) Expression of CYP2E1 in human nasopharynx and its metabolic effect in vitro.De-Fu Hou et al.Molecular and cellular biochemistry, 298(1-2), 93-100 (2006-12-06)

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