沸点	239 ºC
闪点	51 ºC
密度	1.169
折射率	1.583-1.585

危险品标志	Xn
危险类别码	R10;R20/21/22;R36/37/38
安全说明书	S16;S26;S36/37/39

来源	SDS样本
Alfa-Aesar	浏览或下载
Sigma-Aldrich	浏览或下载
TCI	浏览或下载

产品合成路线

更多

名称	CAS号

更多

文章

同行评议文献

Switch in signaling control of mTORC1 activity after oncoprotein expression in thyroid cancer cell lines.Roberta Malaguarnera et al.The Journal of clinical endocrinology and metabolism, 99(10), E1976-E1987 (2014-07-17) Sinapic acid induces the expression of thermogenic signature genes and lipolysis through activation of PKA/CREB signaling in brown adipocytes.Monir Hossain et al.BMB reports, 53(3), 142-147 (2019-08-14) High-density lipoprotein cholesterol efflux capacity as a relevant predictor of atherosclerotic coronary disease.Tetsuya Ishikawa et al.Atherosclerosis, 242(1), 318-322 (2015-08-08) Mapping Atheroprotective Functions and Related Proteins/Lipoproteins in Size Fractionated Human Plasma.Debi K Swertfeger et al.Molecular & cellular proteomics : MCP, 16(4), 680-693 (2017-02-23) Vasodilatory effect of 14,15-epoxyeicosatrienoic acid on mesenteric arteries in hypertensive and aged rats.Cui Yang et al.Prostaglandins & other lipid mediators, 112, 1-8 (2014-06-01) The proliferative phase endometrium in IVF/ICSI: an in-cycle molecular analysis predictive of the outcome following fresh embryo transfer.S Mackens et al.Human reproduction (Oxford, England), 35(1), 130-144 (2020-01-10) Structure-function analyses of the Pth11 receptor reveal an important role for CFEM motif and redox regulation in rice blast.Yanjun Kou et al.The New phytologist, 214(1), 330-342 (2016-11-30) A Cyclic Nucleotide-Gated Channel, HvCNGC2-3, Is Activated by the Co-Presence of Na⁺ and K⁺ and Permeable to Na⁺ and K⁺ Non-Selectively.Izumi C Mori et al.Plants (Basel, Switzerland), 7(3) (2018-07-28) Photochemical crosslinking in oligonucleotide-protein complexes between a bromine-substituted 2-5A analog and 2-5A-dependent RNase by ultraviolet lamp or laser.N L Nolan-Sorden et al.Analytical biochemistry, 184(2), 298-304 (1990-02-01) Onset and Heterogeneity of Responsiveness to FSH in Mouse Preantral Follicles in Culture.Kate Hardy et al.Endocrinology, 158(1), 134-147 (2016-11-08) Evidence on the existence of a purine ligand induced conformational change in the active site of bovine pancreatic ribonuclease A studied by proton nuclear magnetic resonance spectroscopy.C Arús et al.Biochemistry, 21(18), 4290-4297 (1982-08-31) Molecular modeling studies of a parallel stranded quadruplexes containing a 8-bromoadenosine.Veronica Esposito et al.Nucleosides, nucleotides & nucleic acids, 24(5-7), 789-794 (2005-10-27) Steroid biosynthesis by zona glomerulosa-fasciculata cells in primary culture of guinea-pig adrenals.P Provencher et al.Journal of steroid biochemistry, 36(6), 589-596 (1990-08-28) In vitro effects of single and binary mixtures of regulated mycotoxins and persistent organochloride pesticides on steroid hormone production in MA-10 Leydig cell line.Ukpai A Eze et al.Toxicology in vitro : an international journal published in association with BIBRA, 60, 272-280 (2019-06-14) Effects of caffeine on circadian phase, amplitude and period evaluated in cells in vitro and peripheral organs in vivo in PER2::LUCIFERASE mice.Seira Narishige et al.British journal of pharmacology, 171(24), 5858-5869 (2014-08-28) Expressions of Sox9, Sox5, and Sox13 transcription factors in mice testis during postnatal development.Mikella Daigle et al.Molecular and cellular biochemistry, 407(1-2), 209-221 (2015-06-06) βTiina Keränen et al.Cytokine, 94, 1-7 (2017-02-07) The relationship between pulsatile GnRH secretion and cAMP production in immortalized GnRH neurons.John L Frattarelli et al.American journal of physiology. Endocrinology and metabolism, 300(6), E1022-E1030 (2011-03-31) Modulation of signaling through GPCR-cAMP-PKA pathways by PDE4 depends on stimulus intensity: Possible implications for the pathogenesis of acrodysostosis without hormone resistance.Emmanuelle Motte et al.Molecular and cellular endocrinology, 442, 1-11 (2016-12-03) Organoids of Human Endometrium: A Powerful In Vitro Model for the Endometrium-Embryo Cross-Talk at the Implantation Site.Alice Luddi et al.Cells, 9(5) (2020-05-06) Expression of the facilitated glucose transporters (GLUT1 and GLUT3) by a choriocarcinoma cell line (JAr) and cytotrophoblast cells in culture.L H Clarson et al.Placenta, 18(4), 333-339 (1997-05-01) ADAM12-directed ectodomain shedding of E-cadherin potentiates trophoblast fusion.M Aghababaei et al.Cell death and differentiation, 22(12), 1970-1984 (2015-04-25) Regulation of the human NBC3 Na+/HCO3- cotransporter by carbonic anhydrase II and PKA.Frederick B Loiselle et al.American journal of physiology. Cell physiology, 286(6), C1423-C1433 (2004-01-23) Characterization of the interaction between 8-bromoadenosine with human serum albumin and its analytical application.Fengling Cui et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 74(4), 964-971 (2009-09-25) Cyclic AMP-dependent protein kinase A and EPAC mediate VIP and secretin stimulation of PAK4 and activation of Na+,K+-ATPase in pancreatic acinar cells.Irene Ramos-Alvarez et al.American journal of physiology. Gastrointestinal and liver physiology, 316(2), G263-G277 (2018-12-07) Bromo-adenosine stimulates choriogonadotropin production in JAr and cytotrophoblast cells: evidence for effects on two stages of differentiation.C P Sibley et al.Molecular endocrinology (Baltimore, Md.), 5(4), 582-586 (1991-04-01) Transcription factors SF1 and cJUN cooperate to activate the Fdx1 promoter in MA-10 Leydig cells.Pauline Roumaud et al.The Journal of steroid biochemistry and molecular biology, 171, 121-132 (2017-03-10) Lithium and GADL1 regulate glycogen synthase kinase-3 activity to modulate KCTD12 expression.Tai-Na Wu et al.Scientific reports, 9(1), 10255-10255 (2019-07-18) Channelrhodopsin-1 Phosphorylation Changes with Phototactic Behavior and Responds to Physiological Stimuli in Chlamydomonas.Michaela Böhm et al.The Plant cell, 31(4), 886-910 (2019-03-14) Synthesis of the 2'-deoxy-2'-fluoro and 3'-deoxy-3'-fluoro analogues of 8-bromoadenosine.T Maruyama et al.Nucleic acids symposium series, (37)(37), 17-18 (1997-01-01) Prostaglandin E2--mediated relaxation of the ductus arteriosus: effects of gestational age on g protein-coupled receptor expression, signaling, and vasomotor control.Nahid Waleh et al.Circulation, 110(16), 2326-2332 (2004-10-13) Arginine reprogramming in ADPKD results in arginine-dependent cystogenesis.Josephine F Trott et al.American journal of physiology. Renal physiology, 315(6), F1855-F1868 (2018-10-04) Prostaglandin E2 suppresses hCAP18/LL-37 expression in human macrophages via EP2/EP4: implications for treatment of Mycobacterium tuberculosis infection.Min Wan et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(5), 2827-2840 (2018-02-07) Selective generation and reactivity of 5'-adenosinyl and 2'-adenosinyl radicals.Chryssostomos Chatgilialoglu et al.Chemistry (Weinheim an der Bergstrasse, Germany), 10(5), 1249-1255 (2004-03-10) Inhibition of progesterone biosynthesis induced by deca-brominated diphenyl ether (BDE-209) in mouse Leydig tumor cell (MLTC-1).Xiumei Han et al.Toxicology in vitro : an international journal published in association with BIBRA, 60, 383-388 (2019-05-28) Androgens regulate follicle stage-dependent pro- and anti-apoptosis in teleost ovaries through ZIP9 activation of different G proteins†.Aubrey Converse et al.Biology of reproduction, 101(2), 377-391 (2019-05-11) Enhanced neurite outgrowth of human model (NT2) neurons by small-molecule inhibitors of Rho/ROCK signaling.Frank Roloff et al.PloS one, 10(2), e0118536-e0118536 (2015-02-26) CNGC2 Is a Ca2+ Influx Channel That Prevents Accumulation of Apoplastic Ca2+ in the Leaf.Yan Wang et al.Plant physiology, 173(2), 1342-1354 (2016-12-22) The mammalian decidual cell evolved from a cellular stress response.Eric M Erkenbrack et al.PLoS biology, 16(8), e2005594-e2005594 (2018-08-25) Synergistic effect of phosphodiesterase 4 inhibitor and serum on migration of endotoxin-stimulated macrophages.Jing-Xing Yang et al.Innate immunity, 24(8), 501-512 (2018-11-10) Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages.Milena Sokolowska et al.Journal of immunology (Baltimore, Md. : 1950), 194(11), 5472-5487 (2015-04-29) Shockwaves Suppress Adipocyte Differentiation via Decrease in PPARγ.Wonkyoung Cho et al.Cells, 9(1) (2020-01-16) MEF2 Cooperates With Forskolin/cAMP and GATA4 to Regulate Star Gene Expression in Mouse MA-10 Leydig Cells.Caroline Daems et al.Endocrinology, 156(7), 2693-2703 (2015-04-11) Chlamydia trachomatis infection of human endometrial stromal cells induces defective decidualisation and chemokine release.Sevi Giakoumelou et al.Scientific reports, 7(1), 2001-2001 (2017-05-19) Decidualization induces a secretome switch in perivascular niche cells of the human endometrium.Keisuke Murakami et al.Endocrinology, 155(11), 4542-4553 (2014-08-15) The effect of adenosine on cochlear potentials in the guinea pig.K Nario et al.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 251(7), 428-433 (1994-01-01) Bronchioalveolar stem cells derived from mouse-induced pluripotent stem cells promote airway epithelium regeneration.Naoya Kawakita et al.Stem cell research & therapy, 11(1), 430-430 (2020-10-04) Synthesis and properties of a modified 2'-5'-adenylate trimer containing 2'-terminal 8-bromoadenosine.S Yoshida et al.Nucleic acids symposium series, (16)(16), 133-136 (1985-01-01) Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium.Margherita Y Turco et al.Nature cell biology, 19(5), 568-577 (2017-04-11) High-quality human preimplantation embryos stimulate endometrial stromal cell migration via secretion of microRNA hsa-miR-320a.Robbert P Berkhout et al.Human reproduction (Oxford, England), 35(8), 1797-1807 (2020-07-10) Transcriptomic responses to hypoxia in endometrial and decidual stromal cells.Kalle T Rytkönen et al.Reproduction (Cambridge, England), 160(1), 39-51 (2020-04-10) Bronchoalveolar sublineage specification of pluripotent stem cells: effect of dexamethasone plus cAMP-elevating agents and keratinocyte growth factor.Katherina Katsirntaki et al.Tissue engineering. Part A, 21(3-4), 669-682 (2014-10-16) Internalized TSH receptors en route to the TGN induce local GAmod Godbole et al.Nature communications, 8(1), 443-443 (2017-09-07) PKA signaling drives mammary tumorigenesis through Src.A G Beristain et al.Oncogene, 34(9), 1160-1173 (2014-03-26) Glycolytic Switch Is Required for Transdifferentiation to Endothelial Lineage.Li Lai et al.Circulation, 139(1), 119-133 (2018-12-28) Regulation of Neuronal Na+/K+-ATPase by Specific Protein Kinases and Protein Phosphatases.Sandesh Mohan et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(28), 5440-5451 (2019-05-16) The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease.Andre F Batista et al.The Journal of pathology, 245(1), 85-100 (2018-02-13) Purine 8-bromination modulates the ribonuclease L binding and activation abilities of 2',5'-oligoadenylates. Possible influence of glycosyl torsion angle.K Lesiak et al.The Journal of biological chemistry, 262(5), 1961-1965 (1987-02-15) Conformational analysis of brominated pA2'-5'A2'-5'A analogs. An NMR and model-building study.Y T van den Hoogen et al.European journal of biochemistry, 182(3), 629-637 (1989-07-01) Regulation of stanniocalcin-1 secretion by BeWo cells and first trimester human placental tissue from normal pregnancies and those at increased risk of developing preeclampsia.Naila Abid et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(5), 6086-6098 (2020-03-13) Regulation of epithelial Na+ transport by soluble adenylyl cyclase in kidney collecting duct cells.Kenneth R Hallows et al.The Journal of biological chemistry, 284(9), 5774-5783 (2009-01-08) Ganoderic acid A is the effective ingredient of Ganoderma triterpenes in retarding renal cyst development in polycystic kidney disease.Jia Meng et al.Acta pharmacologica Sinica, 41(6), 782-790 (2020-01-09) Maintenance of hindgut reabsorption during cold exposure is a key adaptation for Drosophila cold tolerance.Mads Kuhlmann Andersen et al.The Journal of experimental biology, 223(Pt 4) (2020-01-19) Anticystogenic activity of a small molecule PAK4 inhibitor may be a novel treatment for autosomal dominant polycystic kidney disease.Vicki J Hwang et al.Kidney international, 92(4), 922-933 (2017-05-27) Emodin augments calcium activated chloride channel in colonic smooth muscle cells by Gi/Go protein.Long Xu et al.European journal of pharmacology, 615(1-3), 171-176 (2009-05-05) Bisphenol compounds regulate decidualized stromal cells in modulating trophoblastic spheroid outgrowth and invasion in vitro†.Hongjie Fan et al.Biology of reproduction, 102(3), 693-704 (2019-11-20) Adenosine 3':5'-cyclic monophosphate induces regulated secretion of tissue-type plasminogen activator and von Willebrand factor from cultured human endothelial cells.R J Hegeman et al.Thrombosis and haemostasis, 79(4), 853-858 (1998-05-06) CaFabio Fusi et al.Biochemical pharmacology, 140, 53-63 (2017-06-07) Crosstalk from cAMP to ERK1/2 emerges during postnatal maturation of nociceptive neurons and is maintained during aging.Joerg Isensee et al.Journal of cell science, 130(13), 2134-2146 (2017-05-19) Inferring biallelism of two FSH receptor mutations associated with spontaneous ovarian hyperstimulation syndrome by evaluating FSH, LH and HCG cross-activity.Clara Lazzaretti et al.Reproductive biomedicine online, 38(5), 816-824 (2019-03-27) The role of inhibition of pyruvate kinase in the stimulation of gluconeogenesis by glucagon: a reevaluation.R C Haynes et al.Archives of biochemistry and biophysics, 283(1), 51-59 (1990-11-15) Functional polarization of human hepatoma HepaRG cells in response to forskolin.Abdullah Mayati et al.Scientific reports, 8(1), 16115-16115 (2018-11-02) Patterns of human chorionic gonadotropin expression in untreated and 8-bromoadenosine-treated JAR choriocarcinoma cells.R E Martell et al.Endocrinology, 126(5), 2757-2764 (1990-05-01) The Effect of Copper on Endometrial Receptivity and Induction of Apoptosis on Decidualized Human Endometrial Stromal Cells.Jose P Carrascosa et al.Reproductive sciences (Thousand Oaks, Calif.), 25(7), 985-999 (2017-10-07) Fibroblast Growth Factor 7 Regulates Proliferation and Decidualization of Human Endometrial Stromal Cells via ERK and JNK Pathway in an Autocrine Manner.Wen-Jie Zhou et al.Reproductive sciences (Thousand Oaks, Calif.), 24(12), 1607-1619 (2017-03-09) Two-step synthesis of novel, bioactive derivatives of the ubiquitous cofactor nicotinamide adenine dinucleotide (NAD).Thomas Pesnot et al.Journal of medicinal chemistry, 54(10), 3492-3499 (2011-05-03) Relation of High-Density Lipoprotein Charge Heterogeneity, Cholesterol Efflux Capacity, and the Expression of High-Density Lipoprotein-Related Genes in Mononuclear Cells to the HDL-Cholesterol Level.Alexander D Dergunov et al.Lipids, 53(10), 979-991 (2018-11-16) Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial Progenitor Cells.Antonella F M Dost et al.Cell stem cell, 27(4), 663-678 (2020-09-07) Restoration of the cAMP second messenger pathway enhances cardiac preservation for transplantation in a heterotopic rat model.D Pinsky et al.The Journal of clinical investigation, 92(6), 2994-3002 (1993-12-01) T-2 toxin downregulates LHCGR expression, steroidogenesis, and cAMP level in human cumulus granulosa cells.Kristina Pogrmic-Majkic et al.Environmental toxicology, 34(7), 844-852 (2019-04-06) Deregulation of the endometrial stromal cell secretome precedes embryo implantation failure.Ruban Rex Peter Durairaj et al.Molecular human reproduction, 23(7), 478-487 (2017-04-13) EGF domain of coagulation factor IX is conducive to exposure of phosphatidylserine.Chiaki Hidai et al.Cell biology international, 41(4), 374-383 (2017-02-06) Functional characterization of the human facilitative glucose transporter 12 (GLUT12) by electrophysiological methods.Jonai Pujol-Giménez et al.American journal of physiology. Cell physiology, 308(12), C1008-C1022 (2015-04-10) Divergent Roles for cAMP-PKA Signaling in the Regulation of Filamentous Growth in Saccharomyces cerevisiae and Saccharomyces bayanus.Ömur Kayikci et al.G3 (Bethesda, Md.), 8(11), 3529-3538 (2018-09-15) Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing.Anna M D Végh et al.Molecules (Basel, Switzerland), 24(1) (2019-01-10) High Tidal Volume Induces Mitochondria Damage and Releases Mitochondrial DNA to Aggravate the Ventilator-Induced Lung Injury.Jin-Yuan Lin et al.Frontiers in immunology, 9, 1477-1477 (2018-07-19) Decreased hyperpolarization-activated cyclic nucleotide-gated channels are involved in bladder dysfunction associated with spinal cord injury.Qian Liu et al.International journal of molecular medicine, 41(5), 2609-2618 (2018-02-14) Ultraviolet-induced 8,8-adenine dehydrodimers in oligo- and polynucleotides.F P Gasparro et al.Nucleic acids research, 14(10), 4239-4251 (1986-05-27) Human induced pluripotent stem cell-derived lung progenitor and alveolar epithelial cells attenuate hyperoxia-induced lung injury.Mehdi Shafa et al.Cytotherapy, 20(1), 108-125 (2017-10-24) Adrenal fasciculata cells express T-type and rapidly and slowly activating L-type Ca2+ channels that regulate cortisol secretion.John J Enyeart et al.American journal of physiology. Cell physiology, 308(11), C899-C918 (2015-03-20) Increased expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in reactive astrocytes following ischemia.Pavel Honsa et al.Glia, 62(12), 2004-2021 (2014-07-22) Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors.Killian Hurley et al.Cell stem cell, 26(4), 593-608 (2020-02-01) Prostacyclin regulates bone growth via the Epac/Rap1 pathway.Michele R Hutchison et al.Endocrinology, 156(2), 499-510 (2014-11-19)

备注