
L-Homophenylalanine | CAS:943-73-7
L-Homophenylalanine
- 名称:S-苯基丁氨酸; L-2-氨基-4-苯基丁酸 | L-Homophenylalanine
- CAS号:943-73-7
- 别名:(S)-alpha-Amino-benzenebutanoic acid; (+)-2-Amino-4-phenylbutyric acid
- 分子式:C10H13NO2
- 分子量:179.22
- EINESC号:213-403-3
产品描述
物理化学性质
熔点 | 300 ºC |
---|---|
比旋光度 | 45 º (C=1, 3N HCl 19 º |
安全数据
安全说明书 | S24/25 |
---|
产品合成路线
名称 | CAS号 |
---|
更多
文章
同行评议文献
Chronotropic and inotropic actions of amrinone, carbazeran and isobutylmethyl xanthine: role of phosphodiesterase inhibition.M Shahid et al.British journal of pharmacology, 98(1), 291-301 (1989-09-01)
A species difference in the presystemic metabolism of carbazeran in dog and man.B Kaye et al.Xenobiotica; the fate of foreign compounds in biological systems, 14(12), 935-945 (1984-12-01)
Molecular Cloning and Characterization of Marmoset Aldehyde Oxidase.Shotaro Uehara et al.Drug metabolism and disposition: the biological fate of chemicals, 45(8), 883-886 (2017-05-11)
Biotransformation of carbazeran in guinea pig: effect of hydralazine pretreatment.D J Critchley et al.Xenobiotica; the fate of foreign compounds in biological systems, 24(1), 37-47 (1994-01-01)
Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug Metabolism.T Eric Ballard et al.Drug metabolism and disposition: the biological fate of chemicals, 44(2), 172-179 (2015-11-27)
Aldehyde oxidase activity in fresh human skin.Nenad Manevski et al.Drug metabolism and disposition: the biological fate of chemicals, 42(12), 2049-2057 (2014-09-25)
A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834.Jasleen K Sodhi et al.Drug metabolism and disposition: the biological fate of chemicals, 43(6), 908-915 (2015-04-08)
Phosphodiesterase inhibitors: haemodynamic effects related to the treatment of cardiac failure.W S Hillis et al.European heart journal, 3 Suppl D, 97-101 (1982-12-01)
Oxidative metabolism of carbazeran in vitro by liver cytosol of baboon and man.B Kaye et al.Xenobiotica; the fate of foreign compounds in biological systems, 15(3), 237-242 (1985-03-01)
Deuterium isotope effects on drug pharmacokinetics. I. System-dependent effects of specific deuteration with aldehyde oxidase cleared drugs.Raman Sharma et al.Drug metabolism and disposition: the biological fate of chemicals, 40(3), 625-634 (2011-12-23)
Comparative pharmacology and clinical efficacy of newer agents in treatment of heart failure.C R Taylor et al.American heart journal, 102(3 Pt 2), 515-532 (1981-09-01)
Evaluation of Carbazeran 4-Oxidation and O6-Benzylguanine 8-Oxidation as Catalytic Markers of Human Aldehyde Oxidase: Impact of Cytosolic Contamination of Liver Microsomes.Jiarong Xie et al.Drug metabolism and disposition: the biological fate of chemicals, 47(1), 26-37 (2018-10-20)
Drug Metabolism: Towards the Next Millennium, 45-45 (1998)
Comparison of predictability for human pharmacokinetics parameters among monkeys, rats, and chimeric mice with humanised liver.Maki Miyamoto et al.Xenobiotica; the fate of foreign compounds in biological systems, 47(12), 1052-1063 (2016-11-29)
Minipig and Human Metabolism of Aldehyde Oxidase Substrates: In Vitro-In Vivo Comparisons.David J Wilkinson et al.The AAPS journal, 19(4), 1163-1174 (2017-05-06)
Proteolysis of cyclic AMP phosphodiesterase-II attenuates its ability to be inhibited by compounds which exert positive inotropic actions in cardiac tissue.B Price et al.Biochemical pharmacology, 36(23), 4047-4054 (1987-12-01)
Human Aldehyde Oxidase 1-Mediated Carbazeran Oxidation in Chimeric TK-NOG Mice Transplanted with Human Hepatocytes.Shotaro Uehara et al.Drug metabolism and disposition: the biological fate of chemicals, 48(7), 580-586 (2020-05-03)
In Vitro Inhibition of Human Aldehyde Oxidase Activity by Clinically Relevant Concentrations of Gefitinib and Erlotinib: Comparison with Select Metabolites, Molecular Docking Analysis, and Impact on Hepatic Metabolism of Zaleplon and Methotrexate.Wee Kiat Tan et al.The Journal of pharmacology and experimental therapeutics, 374(2), 295-307 (2020-05-13)
The new inotropic phosphodiesterase inhibitors.D el Allaf et al.Archives internationales de physiologie et de biochimie, 92(4), S69-S79 (1984-11-01)
备注
Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).
名称 | CAS号 |
---|

相关产品
相关资讯
问
热门标签
询 单
请 填 写 相 关 信 息
- 请填写产品名称!
- CAS号
- 请正确填写公司名称!
- 请正确填写联系人!
- 请正确填写联系电话!
- 请正确填写联系邮箱!
- 请描述您的问题!