
3'-Bromo-4'-fluoroacetophenone | CAS:1007-15-4
3'-Bromo-4'-fluoroacetophenone
- 名称:3-溴-4-氟苯甲酮 | 3'-Bromo-4'-fluoroacetophenone
- CAS号:1007-15-4
- 别名:1-(3-Bromo-4-fluorophenyl)ethan-1-one
- 分子式:C8H6BrFO
- 分子量:217.04
- EINESC号:213-750-0
产品描述
物理化学性质
熔点 | 51-56 ºC |
---|
安全数据
危险品标志 | Xi |
---|---|
危险类别码 | R36/37/38 |
安全说明书 | S26;S37/39 |
产品合成路线
名称 | CAS号 |
---|
更多
文章
同行评议文献
Simultaneous determination of various bioactive redox components in Shuang-Huang-Lian preparations using a novel three-channel isocratic elution liquid chromatography with electrochemical detection system.Liangmian Chen et al.Journal of pharmaceutical and biomedical analysis, 95, 93-101 (2014-03-25)
Flavonoids in Scutellaria immaculata and S. ramosissima (Lamiaceae) and their biological activity.Nilufar Z Mamadalieva et al.The Journal of pharmacy and pharmacology, 63(10), 1346-1357 (2011-09-09)
Research on scutellarin parenteral solution's protective effects in rats with severe acute pancreatitis and multiple organ injuries.Chen Hanqing et al.Inflammation, 35(3), 1005-1014 (2011-11-23)
Non-Linear Quantitative Structure⁻Activity Relationships Modelling, Mechanistic Study and In-Silico Design of Flavonoids as Potent Antioxidants.Petar Žuvela et al.International journal of molecular sciences, 20(9) (2019-05-15)
Scutellarin suppresses neuroinflammation via the inhibition of the AKT/NF-κB and p38/JNK pathway in LPS-induced BV-2 microglial cells.Pengtao You et al.Naunyn-Schmiedeberg's archives of pharmacology, 391(7), 743-751 (2018-04-24)
[Scutellarin starch microspheres' permeability through nasal mucosa of different animals in vitro].Shanghe Ye et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(5), 663-666 (2012-06-15)
Scutellarin may alleviate cognitive deficits in a mouse model of hypoxia by promoting proliferation and neuronal differentiation of neural stem cells.Wei-Wei Wang et al.Iranian journal of basic medical sciences, 20(3), 272-279 (2017-04-11)
[Evaluation on preparation process of brevisapin colon-specific tables and its in vitro release].Yan-Ling Li et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(6), 817-820 (2013-05-31)
Scutellarin induces apoptosis and autophagy in NSCLC cells through ERK1/2 and AKT Signaling Pathways in vitro and in vivo.ChaoYue Sun et al.Journal of Cancer, 9(18), 3247-3256 (2018-10-03)
[Intestinal lymphatic transport of breviscapine orally administered in rat].Yi-juan Gong et al.Yao xue xue bao = Acta pharmaceutica Sinica, 46(10), 1262-1267 (2012-01-17)
Scutellarin Mitigates Aβ-Induced Neurotoxicity and Improves Behavior Impairments in AD Mice.Yue-Qin Zeng et al.Molecules (Basel, Switzerland), 23(4) (2018-04-13)
Effects of spray-drying and choice of solid carriers on concentrations of Labrasol® and Transcutol® in solid self-microemulsifying drug delivery systems (SMEDDS).Liang Li et al.Molecules (Basel, Switzerland), 18(1), 545-560 (2013-01-04)
Scutellarin regulates the Notch pathway and affects the migration and morphological transformation of activated microglia in experimentally induced cerebral ischemia in rats and in activated BV-2 microglia.Yun Yuan et al.Journal of neuroinflammation, 12, 11-11 (2015-01-21)
Determination of aglycone conjugated metabolites of scutellarin in rat plasma by HPLC.Jianming Huang et al.Journal of pharmaceutical and biomedical analysis, 40(2), 465-471 (2005-09-27)
Scutellarin protects against vascular endothelial dysfunction and prevents atherosclerosis via antioxidation.Jiao Mo et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 42, 66-74 (2018-04-16)
Design, synthesis and biological evaluation of glucose-containing scutellarein derivatives as neuroprotective agents based on metabolic mechanism of scutellarin in vivo.Nian-Guang Li et al.Bioorganic & medicinal chemistry letters, 23(1), 102-106 (2012-11-28)
Effect of light, methyl jasmonate and cyclodextrin on production of phenolic compounds in hairy root cultures of Scutellaria lateriflora.Zachary Marsh et al.Phytochemistry, 107, 50-60 (2014-09-23)
Comparative analysis of 15 chemical constituents in Scutellaria baicalensis stem-leaf from different regions in China by ultra-high performance liquid chromatography with triple quadrupole tandem mass spectrometry.Baofei Yan et al.Journal of separation science, 40(18), 3570-3581 (2017-07-08)
Scutellarin circumvents chemoresistance, promotes apoptosis, and represses tumor growth by HDAC/miR-34a-mediated down-modulation of Akt/mTOR and NF-κB-orchestrated signaling pathways in multiple myeloma.Lan Li et al.International journal of clinical and experimental pathology, 13(2), 212-219 (2020-03-27)
Sustained release and enhanced bioavailability of injectable scutellarin-loaded bovine serum albumin nanoparticles.Yuanfeng Wei et al.International journal of pharmaceutics, 476(1-2), 142-148 (2014-10-01)
Scutellarin from Scutellaria baicalensis suppresses adipogenesis by upregulating PPARα in 3T3-L1 cells.Kaihui Lu et al.Journal of natural products, 76(4), 672-678 (2013-03-26)
[Influence of scutellarin on oxidative stress and neuronal apoptosis of rats with dementia].Li-li Guo et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 34(2), 237-241 (2011-08-10)
Simultaneous quantitation of 23 bioactive compounds in Tanreqing capsule by high-performance liquid chromatography electrospray ionization tandem mass spectrometry.Yining Zhao et al.Biomedical chromatography : BMC, 33(7), e4531-e4531 (2019-03-09)
Scutellarin inhibits cytochrome P450 isoenzyme 1A2 (CYP1A2) in rats.Tun-Yu Jian et al.Phytotherapy research : PTR, 26(8), 1226-1230 (2012-01-10)
EFFECT OF PERILLA FRUTESCENS EXTRACTS AND ROSMARINIC ACID ON RAT HEART MITOCHONDRIAL FUNCTIONS.Lina Raudone et al.Acta poloniae pharmaceutica, 73(1), 135-145 (2016-03-25)
Scutellarin attenuates human-neutrophil-elastase-induced mucus production by inhibiting the PKC-ERK signaling pathway in vitro and in vivo.De-Peng Jiang et al.The American journal of Chinese medicine, 39(6), 1193-1206 (2011-11-16)
Enhanced encapsulation and bioavailability of breviscapine in PLGA microparticles by nanocrystal and water-soluble polymer template techniques.Hong Wang et al.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 115, 177-185 (2017-03-07)
Engineering yeast for the production of breviscapine by genomic analysis and synthetic biology approaches.Xiaonan Liu et al.Nature communications, 9(1), 448-448 (2018-02-02)
Scutellarin protects against Aβ-induced learning and memory deficits in rats: involvement of nicotinic acetylcholine receptors and cholinesterase.Li-li Guo et al.Acta pharmacologica Sinica, 32(12), 1446-1453 (2011-10-12)
Neuroprotective effects of scutellarin against hypoxic-ischemic-induced cerebral injury via augmentation of antioxidant defense capacity.Hong Guo et al.The Chinese journal of physiology, 54(6), 399-405 (2012-01-11)
[Simultaneous determination of protocatechuic acid, isoorientin and scutellarin in rat tissues after a single intravenous administration of compound hongcao for injection by UPLC-MS/MS].Yong Huang et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(22), 3189-3193 (2012-03-02)
Preparation, characterization and evaluation of breviscapine lipid emulsions coated with monooleate-PEG-COOH.Fei Xiong et al.International journal of pharmaceutics, 421(2), 275-282 (2011-10-18)
Scutellarin-cyclodextrin conjugates: synthesis, characterization and anticancer activity.Bo Yang et al.Carbohydrate polymers, 92(2), 1308-1314 (2013-02-13)
DGKγ Knock-Out Mice Show Impairments in Cerebellar Motor Coordination, LTD, and the Dendritic Development of Purkinje Cells through the Activation of PKCγ.Ryosuke Tsumagari et al.eNeuro, 7(2) (2020-02-09)
Synthesis and protective effect of scutellarein on focal cerebral ischemia/reperfusion in rats.Lihua Qian et al.Molecules (Basel, Switzerland), 17(9), 10667-10674 (2012-09-08)
[Simultaneous determination of isoorientin, scutellarin and cynaroside in rat plasma and pharmacokinetics by UPLC-MS/MS].Yong Huang et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(4), 529-532 (2012-06-07)
In vivo effects of scutellarin on the activities of CYP1A2, CYP2C11, CYP2D1, and CYP3A1/2 by cocktail probe drugs in rats.Zhiping Lin et al.Die Pharmazie, 69(7), 537-541 (2014-07-31)
Intranasal administration of brain-targeted HP-β-CD/chitosan nanoparticles for delivery of scutellarin, a compound with protective effect in cerebral ischaemia.Shanshan Liu et al.The Journal of pharmacy and pharmacology, 69(11), 1495-1501 (2017-08-16)
Scutellarin protects against the liver injury induced by diosbulbin B in mice and its mechanism.Chengwei Niu et al.Journal of ethnopharmacology, 164, 301-308 (2015-02-24)
Novel function of scutellarin in inhibiting cell proliferation and inducing cell apoptosis of human Burkitt lymphoma Namalwa cells.Yizhong Feng et al.Leukemia & lymphoma, 53(12), 2456-2464 (2012-05-16)
[Advances in studies on pharmacokinetics of scutellarin and scutellarein].Jianming Liu et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 34(24), 3165-3168 (2010-04-01)
Integrated Transcript and Metabolite Profiles Reveal That EbCHI Plays an Important Role in Scutellarin Accumulation in Erigeron breviscapus Hairy Roots.Ruibing Chen et al.Frontiers in plant science, 9, 789-789 (2018-07-18)
Mechanistic studies on the absorption and disposition of scutellarin in humans: selective OATP2B1-mediated hepatic uptake is a likely key determinant for its unique pharmacokinetic characteristics.Chunying Gao et al.Drug metabolism and disposition: the biological fate of chemicals, 40(10), 2009-2020 (2012-07-24)
Flavonoid composition of Juniperus oblonga Bieb.D I Pisarev et al.Bulletin of experimental biology and medicine, 150(6), 714-717 (2012-01-12)
Differential regulation of baicalin and scutellarin on AMPK and Akt in promoting adipose cell glucose disposal.Le-Le Yang et al.Biochimica et biophysica acta, 1863(2), 598-606 (2016-12-03)
Determination of scutellarin in rat plasma by high-performance liquid chromatography with ultraviolet detectionZhong D, et al. Journal of Chromatography. B, Biomedical Sciences and Applications, 796(2), 439-444 (2003)
Scutellarin benzyl ester partially secured the ischemic injury by its anti-apoptosis mechanism in cardiomyocytes of neonatal rats.Hao Dai et al.Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 9(9), 1014-1021 (2011-09-13)
Scutellarin ameliorates cartilage degeneration in osteoarthritis by inhibiting the Wnt/β-catenin and MAPK signaling pathways.Fuen Liu et al.International immunopharmacology, 78, 105954-105954 (2019-11-24)
Comparative studies on interactions of baicalein, baicalin and scutellarin with lysozyme.Yun Huang et al.European journal of medicinal chemistry, 46(12), 6039-6045 (2011-11-05)
Scutellarin suppresses migration and invasion of human hepatocellular carcinoma by inhibiting the STAT3/Girdin/Akt activity.Yang Ke et al.Biochemical and biophysical research communications, 483(1), 509-515 (2016-12-22)
Scutellarin inhibits translocation of protein kinase C in diabetic thoracic aorta of the rat.Yingxue Su et al.Clinical and experimental pharmacology & physiology, 39(2), 136-140 (2011-11-19)
Improved oral bioavailability of breviscapine via a Pluronic P85-modified liposomal delivery system.Yue Zhou et al.The Journal of pharmacy and pharmacology, 66(7), 903-911 (2014-04-05)
[Studies on the chemical constituents from Conyza canadensis].Hong-Li Liu et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 34(5), 718-720 (2011-10-01)
Plasma protein binding of dietary polyphenols to human serum albumin: A high performance affinity chromatography approach.Hui Cao et al.Food chemistry, 270, 257-263 (2018-09-04)
Scutellarin protects against doxorubicin-induced acute cardiotoxicity and regulates its accumulation in the heart.Xi-Peng Sun et al.Archives of pharmacal research, 40(7), 875-883 (2017-03-21)
Scutellarin suppresses growth and causes apoptosis of human colorectal cancer cells by regulating the p53 pathway.Ning Yang et al.Molecular medicine reports, 15(2), 929-935 (2016-12-31)
Identification and characterization of chemical constituents in Dengzhan Shengmai Capsule and their metabolites in rat plasma by ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry.Xuemei Mu et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1108, 54-64 (2019-01-27)
Elucidation of the mechanism behind the potentiating activity of baicalin against Burkholderia cenocepacia biofilms.Lisa Slachmuylders et al.PloS one, 13(1), e0190533-e0190533 (2018-01-03)
备注
Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).
名称 | CAS号 |
---|

相关产品
相关资讯
问
热门标签
询 单
请 填 写 相 关 信 息
- 请填写产品名称!
- CAS号
- 请正确填写公司名称!
- 请正确填写联系人!
- 请正确填写联系电话!
- 请正确填写联系邮箱!
- 请描述您的问题!