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3'-Bromo-4'-fluoroacetophenone | CAS:1007-15-4
3'-Bromo-4'-fluoroacetophenone
  • 名称:3-溴-4-氟苯甲酮 | 3'-Bromo-4'-fluoroacetophenone
  • CAS号:1007-15-4
  • 别名:1-(3-Bromo-4-fluorophenyl)ethan-1-one
  • 分子式:C8H6BrFO
  • 分子量:217.04
  • EINESC号:213-750-0

产品描述

物理化学性质

熔点 51-56 ºC

安全数据

危险品标志 Xi
危险类别码 R36/37/38
安全说明书 S26;S37/39

SDS

来源 SDS样本
Alfa-Aesar 浏览或下载
Sigma-Aldrich 浏览或下载
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Simultaneous determination of various bioactive redox components in Shuang-Huang-Lian preparations using a novel three-channel isocratic elution liquid chromatography with electrochemical detection system.Liangmian Chen et al.Journal of pharmaceutical and biomedical analysis, 95, 93-101 (2014-03-25) Flavonoids in Scutellaria immaculata and S. ramosissima (Lamiaceae) and their biological activity.Nilufar Z Mamadalieva et al.The Journal of pharmacy and pharmacology, 63(10), 1346-1357 (2011-09-09) Research on scutellarin parenteral solution's protective effects in rats with severe acute pancreatitis and multiple organ injuries.Chen Hanqing et al.Inflammation, 35(3), 1005-1014 (2011-11-23) Non-Linear Quantitative Structure⁻Activity Relationships Modelling, Mechanistic Study and In-Silico Design of Flavonoids as Potent Antioxidants.Petar Žuvela et al.International journal of molecular sciences, 20(9) (2019-05-15) Scutellarin suppresses neuroinflammation via the inhibition of the AKT/NF-κB and p38/JNK pathway in LPS-induced BV-2 microglial cells.Pengtao You et al.Naunyn-Schmiedeberg's archives of pharmacology, 391(7), 743-751 (2018-04-24) [Scutellarin starch microspheres' permeability through nasal mucosa of different animals in vitro].Shanghe Ye et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(5), 663-666 (2012-06-15) Scutellarin may alleviate cognitive deficits in a mouse model of hypoxia by promoting proliferation and neuronal differentiation of neural stem cells.Wei-Wei Wang et al.Iranian journal of basic medical sciences, 20(3), 272-279 (2017-04-11) [Evaluation on preparation process of brevisapin colon-specific tables and its in vitro release].Yan-Ling Li et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(6), 817-820 (2013-05-31) Scutellarin induces apoptosis and autophagy in NSCLC cells through ERK1/2 and AKT Signaling Pathways in vitro and in vivo.ChaoYue Sun et al.Journal of Cancer, 9(18), 3247-3256 (2018-10-03) [Intestinal lymphatic transport of breviscapine orally administered in rat].Yi-juan Gong et al.Yao xue xue bao = Acta pharmaceutica Sinica, 46(10), 1262-1267 (2012-01-17) Scutellarin Mitigates Aβ-Induced Neurotoxicity and Improves Behavior Impairments in AD Mice.Yue-Qin Zeng et al.Molecules (Basel, Switzerland), 23(4) (2018-04-13) Effects of spray-drying and choice of solid carriers on concentrations of Labrasol® and Transcutol® in solid self-microemulsifying drug delivery systems (SMEDDS).Liang Li et al.Molecules (Basel, Switzerland), 18(1), 545-560 (2013-01-04) Scutellarin regulates the Notch pathway and affects the migration and morphological transformation of activated microglia in experimentally induced cerebral ischemia in rats and in activated BV-2 microglia.Yun Yuan et al.Journal of neuroinflammation, 12, 11-11 (2015-01-21) Determination of aglycone conjugated metabolites of scutellarin in rat plasma by HPLC.Jianming Huang et al.Journal of pharmaceutical and biomedical analysis, 40(2), 465-471 (2005-09-27) Scutellarin protects against vascular endothelial dysfunction and prevents atherosclerosis via antioxidation.Jiao Mo et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 42, 66-74 (2018-04-16) Design, synthesis and biological evaluation of glucose-containing scutellarein derivatives as neuroprotective agents based on metabolic mechanism of scutellarin in vivo.Nian-Guang Li et al.Bioorganic & medicinal chemistry letters, 23(1), 102-106 (2012-11-28) Effect of light, methyl jasmonate and cyclodextrin on production of phenolic compounds in hairy root cultures of Scutellaria lateriflora.Zachary Marsh et al.Phytochemistry, 107, 50-60 (2014-09-23) Comparative analysis of 15 chemical constituents in Scutellaria baicalensis stem-leaf from different regions in China by ultra-high performance liquid chromatography with triple quadrupole tandem mass spectrometry.Baofei Yan et 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compounds in Tanreqing capsule by high-performance liquid chromatography electrospray ionization tandem mass spectrometry.Yining Zhao et al.Biomedical chromatography : BMC, 33(7), e4531-e4531 (2019-03-09) Scutellarin inhibits cytochrome P450 isoenzyme 1A2 (CYP1A2) in rats.Tun-Yu Jian et al.Phytotherapy research : PTR, 26(8), 1226-1230 (2012-01-10) EFFECT OF PERILLA FRUTESCENS EXTRACTS AND ROSMARINIC ACID ON RAT HEART MITOCHONDRIAL FUNCTIONS.Lina Raudone et al.Acta poloniae pharmaceutica, 73(1), 135-145 (2016-03-25) Scutellarin attenuates human-neutrophil-elastase-induced mucus production by inhibiting the PKC-ERK signaling pathway in vitro and in vivo.De-Peng Jiang et al.The American journal of Chinese medicine, 39(6), 1193-1206 (2011-11-16) Enhanced encapsulation and bioavailability of breviscapine in PLGA microparticles by nanocrystal and water-soluble polymer template techniques.Hong Wang et al.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 115, 177-185 (2017-03-07) Engineering yeast for the production of breviscapine by genomic analysis and synthetic biology approaches.Xiaonan Liu et al.Nature communications, 9(1), 448-448 (2018-02-02) Scutellarin protects against Aβ-induced learning and memory deficits in rats: involvement of nicotinic acetylcholine receptors and cholinesterase.Li-li Guo et al.Acta pharmacologica Sinica, 32(12), 1446-1453 (2011-10-12) Neuroprotective effects of scutellarin against hypoxic-ischemic-induced cerebral injury via augmentation of antioxidant defense capacity.Hong Guo et al.The Chinese journal of physiology, 54(6), 399-405 (2012-01-11) [Simultaneous determination of protocatechuic acid, isoorientin and scutellarin in rat tissues after a single intravenous administration of compound hongcao for injection by UPLC-MS/MS].Yong Huang et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(22), 3189-3193 (2012-03-02) Preparation, characterization and evaluation of breviscapine lipid emulsions coated with monooleate-PEG-COOH.Fei Xiong et al.International journal of pharmaceutics, 421(2), 275-282 (2011-10-18) Scutellarin-cyclodextrin conjugates: synthesis, characterization and anticancer activity.Bo Yang et al.Carbohydrate polymers, 92(2), 1308-1314 (2013-02-13) DGKγ Knock-Out Mice Show Impairments in Cerebellar Motor Coordination, LTD, and the Dendritic Development of Purkinje Cells through the Activation of PKCγ.Ryosuke Tsumagari et al.eNeuro, 7(2) (2020-02-09) Synthesis and protective effect of scutellarein on focal cerebral ischemia/reperfusion in rats.Lihua Qian et al.Molecules (Basel, Switzerland), 17(9), 10667-10674 (2012-09-08) [Simultaneous determination of isoorientin, scutellarin and cynaroside in rat plasma and pharmacokinetics by UPLC-MS/MS].Yong Huang et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 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chromatography with ultraviolet detectionZhong D, et al. Journal of Chromatography. B, Biomedical Sciences and Applications, 796(2), 439-444 (2003) Scutellarin benzyl ester partially secured the ischemic injury by its anti-apoptosis mechanism in cardiomyocytes of neonatal rats.Hao Dai et al.Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 9(9), 1014-1021 (2011-09-13) Scutellarin ameliorates cartilage degeneration in osteoarthritis by inhibiting the Wnt/β-catenin and MAPK signaling pathways.Fuen Liu et al.International immunopharmacology, 78, 105954-105954 (2019-11-24) Comparative studies on interactions of baicalein, baicalin and scutellarin with lysozyme.Yun Huang et al.European journal of medicinal chemistry, 46(12), 6039-6045 (2011-11-05) Scutellarin suppresses migration and invasion of human hepatocellular carcinoma by inhibiting the STAT3/Girdin/Akt activity.Yang Ke et al.Biochemical and biophysical research communications, 483(1), 509-515 (2016-12-22) Scutellarin inhibits translocation of protein kinase C in diabetic thoracic aorta of the rat.Yingxue Su et al.Clinical and experimental pharmacology & physiology, 39(2), 136-140 (2011-11-19) Improved oral bioavailability of breviscapine via a Pluronic P85-modified liposomal delivery system.Yue Zhou et al.The Journal of pharmacy and pharmacology, 66(7), 903-911 (2014-04-05) [Studies on the chemical constituents from Conyza canadensis].Hong-Li Liu et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 34(5), 718-720 (2011-10-01) Plasma protein binding of dietary polyphenols to human serum albumin: A high performance affinity chromatography approach.Hui Cao et al.Food chemistry, 270, 257-263 (2018-09-04) Scutellarin protects against doxorubicin-induced acute cardiotoxicity and regulates its accumulation in the heart.Xi-Peng Sun et al.Archives of pharmacal research, 40(7), 875-883 (2017-03-21) Scutellarin suppresses growth and causes apoptosis of human colorectal cancer cells by regulating the p53 pathway.Ning Yang et al.Molecular medicine reports, 15(2), 929-935 (2016-12-31) Identification and characterization of chemical constituents in Dengzhan Shengmai Capsule and their metabolites in rat plasma by ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry.Xuemei Mu et al.Journal of chromatography. 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