4,4-Diethoxy-N,N-dimethyl-1-butanamine | CAS:1116-77-4
4,4-Diethoxy-N,N-dimethyl-1-butanamine
- 名称:4-二甲胺基丁醛缩二乙醇 | 4,4-Diethoxy-N,N-dimethyl-1-butanamine
- CAS号:1116-77-4
- 别名:N,N-Dimethyl-4-aminobutanal diethyl acetal
- 分子式:C10H23NO2
- 分子量:189.30
- EINESC号:
产品描述
物理化学性质
闪点 | 158 ºF |
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密度 | 0.884 |
折射率 | 1.421 |
安全数据
危险品标志 | Xi |
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危险类别码 | R41 |
安全说明书 | S26;S36/37/39 |
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Discovery and optimization of imidazo[1,2-a]pyridine inhibitors of insulin-like growth factor-1 receptor (IGF-1R).Kyle A Emmitte et al.Bioorganic & medicinal chemistry letters, 19(3), 1004-1008 (2008-12-23)
Orally active C-6 heteroaryl- and heterocyclyl-substituted imidazo[1,2-a]pyridine acid pump antagonists (APAs).Nick Bailey et al.Bioorganic & medicinal chemistry letters, 19(13), 3602-3606 (2009-05-27)
One-pot three-component synthesis of 3-nitro-2-arylimidazo[1,2-a]pyridine derivatives using air as an oxidant.Hao Yan et al.Chemistry, an Asian journal, 7(9), 2028-2031 (2012-06-14)
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A novel series of imidazo[1,2-a]pyridine derivatives as HIF-1alpha prolyl hydroxylase inhibitors.Namal C Warshakoon et al.Bioorganic & medicinal chemistry letters, 16(21), 5598-5601 (2006-09-12)
Identification of novel imidazo[1,2-a]pyridine inhibitors targeting M. tuberculosis QcrB.Katherine A Abrahams et al.PloS one, 7(12), e52951-e52951 (2013-01-10)
Imidazo[1,2-a]pyridines susceptible to excited state intramolecular proton transfer: one-pot synthesis via an Ortoleva-King reaction.Anton J Stasyuk et al.The Journal of organic chemistry, 77(13), 5552-5558 (2012-06-06)
Fused heterocycles: synthesis of some new imidazo[1,2-a]- pyridine derivatives.Birgul Ozden Kasimogullari et al.Molecules (Basel, Switzerland), 9(10), 894-901 (2007-11-17)
Functionalized heterocyclic scaffolds derived from Morita-Baylis-Hillman Acetates.Huajian Zhu et al.Chemical communications (Cambridge, England), 49(70), 7738-7740 (2013-07-24)
Design, synthesis and in vitro antimicrobial evaluation of novel Imidazo[1,2-a]pyridine and imidazo[2,1-b][1,3]benzothiazole motifs.Taleb H Al-Tel et al.European journal of medicinal chemistry, 46(5), 1874-1881 (2011-03-19)
Molecular characterization of EP6--a novel imidazo[1,2-a]pyridine based direct 5-lipoxygenase inhibitor.Joanna M Wisniewska et al.Biochemical pharmacology, 83(2), 228-240 (2011-10-27)
Intra-periaqueductal grey microinjections of an imidazo[1,2-b]pyridazine derivative, DM2, affects rostral ventromedial medulla cell activity and shows antinociceptive effect.Enza Palazzo et al.Neuropharmacology, 58(3), 660-667 (2009-12-01)
SAR-study on a new class of imidazo[1,2-a]pyridine-based inhibitors of 5-lipoxygenase.Martina Hieke et al.Bioorganic & medicinal chemistry letters, 22(5), 1969-1975 (2012-02-14)
Colorimetric determination of cysteine by a paper-based assay system using aspartic acid modified gold nanoparticles.Chunye Liu et al.Mikrochimica acta, 187(6), 362-362 (2020-06-02)
Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors.Yoshito Terao et al.Bioorganic & medicinal chemistry letters, 22(24), 7326-7329 (2012-11-14)
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Post Groebke-Blackburn multicomponent protocol: synthesis of new polyfunctional imidazo[1,2-a]pyridine and imidazo[1,2-a]pyrimidine derivatives as potential antimicrobial agents.Taleb H Al-Tel et al.European journal of medicinal chemistry, 45(12), 5848-5855 (2010-10-12)
Synthesis and biological evaluation of 2,3-diarylimidazo[1,2-a]pyridines as antileishmanial agents.Sophie Marhadour et al.European journal of medicinal chemistry, 58, 543-556 (2012-11-21)
Imidazo[1,2-a]pyridine derivatives as inhibitors of TNF-alpha expression in T cells.Jan Rether et al.Bioorganic & medicinal chemistry, 16(3), 1236-1241 (2007-11-24)
Discovery of novel imidazo[1,2-a]pyridines as inhibitors of the insulin-like growth factor-1 receptor tyrosine kinase.Richard Ducray et al.Bioorganic & medicinal chemistry letters, 21(16), 4698-4701 (2011-07-22)
Novel one-pot three component reaction for the synthesis of [2-(alkylsulfanyl)imidazo[1,2-a]pyridin-3-yl](aryl)methanone.Ebrahim Kianmehr et al.Journal of combinatorial chemistry, 12(1), 41-44 (2009-11-13)
IRAK-4 inhibitors. Part III: a series of imidazo[1,2-a]pyridines.George M Buckley et al.Bioorganic & medicinal chemistry letters, 18(12), 3656-3660 (2008-05-27)
Generation and exploration of new classes of antitubercular agents: The optimization of oxazolines, oxazoles, thiazolines, thiazoles to imidazo[1,2-a]pyridines and isomeric 5,6-fused scaffolds.Garrett C Moraski et al.Bioorganic & medicinal chemistry, 20(7), 2214-2220 (2012-03-07)
Three-component, one-pot sequential synthesis of functionalized cyclazines: 3H-1,2a1,3-triazaacenaphthylenes.Hongpeng Sun et al.The Journal of organic chemistry, 77(23), 10745-10751 (2012-11-22)
Synthesis and antiprotozoal activity of novel bis-benzamidino imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines.Mohamed A Ismail et al.Bioorganic & medicinal chemistry, 16(2), 683-691 (2007-11-03)
A base promoted cyclization of N-propargylaminopyridines. Synthesis of imidazo[1,2-a]pyridine derivatives.Suren Husinec et al.Organic letters, 13(9), 2286-2289 (2011-03-31)
Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110alpha inhibitors.Masahiko Hayakawa et al.Bioorganic & medicinal chemistry, 15(1), 403-412 (2006-10-20)
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Efficient solid-phase synthesis of a library of imidazo[1,2-a]pyridine-8-carboxamides.Ahmed Kamal et al.Journal of combinatorial chemistry, 9(2), 267-274 (2007-02-27)
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