5-Bromo-1-pentene | CAS:1119-51-3
5-Bromo-1-pentene
- 名称:5-溴-1-戊烯 | 5-Bromo-1-pentene
- CAS号:1119-51-3
- 别名:
- 分子式:C5H9Br
- 分子量:149.03
- EINESC号:214-281-4
产品描述
物理化学性质
沸点 | 126-127 ºC (765 mmHg) |
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闪点 | 30 ºC |
密度 | 1.258 |
折射率 | 1.462-1.465 |
安全数据
危险品标志 | Xi |
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危险类别码 | R10;R36/37/38 |
安全说明书 | S16;S24/25 |
产品合成路线
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Skin-derived precursor Schwann cells protect SH-SY5Y cells against 6-OHDA-induced neurotoxicity by PI3K/AKT/Bcl-2 pathway.Ying Chen et al.Brain research bulletin, 161, 84-93 (2020-05-04)
Propagation of beta/gamma rhythms in the cortico-basal ganglia circuits of the parkinsonian rat.Timothy O West et al.Journal of neurophysiology, 119(5), 1608-1628 (2018-01-24)
6-Hydroxydopamine induces secretion of PARK7/DJ-1 via autophagy-based unconventional secretory pathway.Yasuomi Urano et al.Autophagy, 14(11), 1943-1958 (2018-08-17)
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Full activation pattern mapping by simultaneous deep brain stimulation and fMRI with graphene fiber electrodes.Siyuan Zhao et al.Nature communications, 11(1), 1788-1788 (2020-04-15)
Immunohistochemical Assessment of the Compensatory Responses in Rat Olfactory Bulbs after 6-Hydroxydopamine-Induced Lesion of the Substantia Nigra.D N Voronkov et al.Bulletin of experimental biology and medicine, 166(6), 811-815 (2019-04-26)
Delta oscillations are a robust biomarker of dopamine depletion severity and motor dysfunction in awake mice.Timothy C Whalen et al.Journal of neurophysiology, 124(2), 312-329 (2020-06-25)
Selective effects of dopamine depletion and L-DOPA therapy on learning-related firing dynamics of striatal neurons.Ledia F Hernandez et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(11), 4782-4795 (2013-03-15)
Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression.Peter Reinhardt et al.Cell stem cell, 12(3), 354-367 (2013-03-12)
A new dopaminergic nigro-olfactory projection.Günter U Höglinger et al.Acta neuropathologica, 130(3), 333-348 (2015-06-15)
Changes in Dendritic Spine Density and Inhibitory Perisomatic Connectivity onto Medium Spiny Neurons in L-Dopa-Induced Dyskinesia.G Gomez et al.Molecular neurobiology, 56(9), 6261-6275 (2019-02-13)
Acetylcholinesterase inhibitory activity and neuroprotection in vitro, molecular docking, and improved learning and memory functions of demethylcurcumin in scopolamine-induced amnesia ICR mice.Yuh-Hwa Liu et al.Food & function, 11(3), 2328-2338 (2020-03-03)
Role of the locus coeruleus catecholaminergic neurons in the chemosensory control of breathing in a Parkinson's disease model.Luiz M Oliveira et al.Experimental neurology, 293, 172-180 (2017-04-23)
Hyperpolarization of the subthalamic nucleus alleviates hyperkinetic movement disorders.Chun-Hwei Tai et al.Scientific reports, 10(1), 8278-8278 (2020-05-20)
Control of Adipocyte Thermogenesis and Lipogenesis through β3-Adrenergic and Thyroid Hormone Signal Integration.Adilson Guilherme et al.Cell reports, 31(5), 107598-107598 (2020-05-07)
Study on antrodia camphorata polysaccharide in alleviating the neuroethology of PD mice by decreasing the expression of NLRP3 inflammasome.Chenyang Han et al.Phytotherapy research : PTR, 33(9), 2288-2297 (2019-07-31)
The α7 nicotinic receptor agonist ABT-107 protects against nigrostriatal damage in rats with unilateral 6-hydroxydopamine lesions.Tanuja Bordia et al.Experimental neurology, 263, 277-284 (2014-09-28)
miR-21 may Act as a Potential Mediator Between Inflammation and Abnormal Bone Formation in Ankylosing Spondylitis Based on TNF-α Concentration-Dependent Manner Through the JAK2/STAT3 Pathway.Yu-Cong Zou et al.Dose-response : a publication of International Hormesis Society, 18(1), 1559325819901239-1559325819901239 (2020-02-06)
Adenosine A1 receptor stimulation reduces D1 receptor-mediated GABAergic transmission from striato-nigral terminals and attenuates l-DOPA-induced dyskinesia in dopamine-denervated mice.Dalila Mango et al.Experimental neurology, 261, 733-743 (2014-09-01)
Late aging-associated increases in L-DOPA-induced dyskinesia are accompanied by heightened neuroinflammation in the hemi-parkinsonian rat.Kathryn Lanza et al.Neurobiology of aging, 81, 190-199 (2019-07-16)
Regulation of dopamine neurotransmission from serotonergic neurons by ectopic expression of the dopamine D2 autoreceptor blocks levodopa-induced dyskinesia.Rhyomi C Sellnow et al.Acta neuropathologica communications, 7(1), 8-8 (2019-01-17)
Neuroprotective Effect of Optimized Yinxieling Formula in 6-OHDA-Induced Chronic Model of Parkinson's Disease through the Inflammation Pathway.Renrong Wei et al.Evidence-based complementary and alternative medicine : eCAM, 2019, 2529641-2529641 (2020-01-14)
Adaptation within mitochondrial oxidative phosphorylation supercomplexes and membrane viscosity during degeneration of dopaminergic neurons in an animal model of early Parkinson's disease.Katarzyna Kuter et al.Biochimica et biophysica acta, 1862(4), 741-753 (2016-02-05)
mitoLUHMES: An Engineered Neuronal Cell Line for the Analysis of the Motility of Mitochondria.Tomasz M Stępkowski et al.Cellular and molecular neurobiology, 37(6), 1055-1066 (2016-11-11)
Procyanidin protects against 6-hydroxydopamine-induced dopaminergic neuron damage via the regulation of the PI3K/Akt signalling pathway.Ying Zhang et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 114, 108789-108789 (2019-03-30)
Antimicrobial Peptide, Lumbricusin, Ameliorates Motor Dysfunction and Dopaminergic Neurodegeneration in a Mouse Model of Parkinson's Disease.Dae Hong Kim et al.Journal of microbiology and biotechnology, 25(10), 1640-1647 (2015-07-29)
Role of nucleus of the solitary tract noradrenergic neurons in post-stress cardiovascular and hormonal control in male rats.Jana Bundzikova-Osacka et al.Stress (Amsterdam, Netherlands), 18(2), 221-232 (2015-03-15)
Serotonergic system in hypoxic ventilatory response in unilateral rat model of Parkinson's disease.Kryspin Andrzejewski et al.Journal of biomedical science, 24(1), 24-24 (2017-03-30)
Orbitofrontal dopamine depletion upregulates caudate dopamine and alters behavior via changes in reinforcement sensitivity.H F Clarke et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(22), 7663-7676 (2014-05-30)
Asymmetrical response of aminopeptidase A in the medial prefrontal cortex and striatum of 6-OHDA-unilaterally-lesioned Wistar Kyoto and spontaneously hypertensive rats.Inmaculada Banegas et al.Pharmacology, biochemistry, and behavior, 182, 12-21 (2019-05-28)
Buspirone requires the intact nigrostriatal pathway to reduce the activity of the subthalamic nucleus via 5-HT1A receptors.A Sagarduy et al.Experimental neurology, 277, 35-45 (2015-12-22)
Pre-administration of BAX-inhibiting peptides decrease the loss of the nigral dopaminergic neurons in rats.Chi Ma et al.Life sciences, 144, 113-120 (2015-11-28)
Nitroxide Radical-Containing Redox Nanoparticles Protect Neuroblastoma SH-SY5Y Cells against 6-Hydroxydopamine Toxicity.Monika Pichla et al.Oxidative medicine and cellular longevity, 2020, 9260748-9260748 (2020-05-08)
Cortical stimulation relieves parkinsonian pathological activity in vitro.Ariadna Aparicio-Juárez et al.The European journal of neuroscience, 49(6), 834-848 (2017-12-19)
The macrocyclic lactones ivermectin and moxidectin show differential effects on rotational behavior in the 6-hydroxydopamine mouse model of Parkinson's disease.Alicia M P Warnecke et al.Behavioural brain research, 393, 112804-112804 (2020-07-16)
(6aR)-11-amino-N-propyl-noraporphine, a new dopamine D2 and serotonin 5-HT1A dual agonist, elicits potent antiparkinsonian action and attenuates levodopa-induced dyskinesia in a 6-OHDA-lesioned rat model of Parkinson's disease.Rui Zhao et al.Pharmacology, biochemistry, and behavior, 124, 204-210 (2014-06-24)
Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's disease.Pingping Song et al.Protein & cell, 7(2), 114-129 (2016-01-10)
Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis.Felipe Henriques et al.Cell reports, 32(5), 107998-107998 (2020-08-07)
Design and synthesis of highly potent and isoform selective JNK3 inhibitors: SAR studies on aminopyrazole derivatives.Ke Zheng et al.Journal of medicinal chemistry, 57(23), 10013-10030 (2014-11-14)
Thioredoxin-Interacting Protein (TXNIP) Regulates Parkin/PINK1-mediated Mitophagy in Dopaminergic Neurons Under High-glucose Conditions: Implications for Molecular Links Between Parkinson's Disease and Diabetes.Cun-Jin Su et al.Neuroscience bulletin, 36(4), 346-358 (2020-01-16)
Protein kinase C delta mediated cytotoxicity of 6-Hydroxydopamine via sustained extracellular signal-regulated kinase 1/2 activation in PC12 cells.Ying Fan et al.Neurological research, 36(1), 53-64 (2013-10-11)
Lipid Analysis of the 6-Hydroxydopamine-Treated SH-SY5Y Cell Model for Parkinson's Disease.Helena Xicoy et al.Molecular neurobiology, 57(2), 848-859 (2019-09-08)
Protective effects of DA-9805 on dopaminergic neurons against 6-hydroxydopamine-induced neurotoxicity in the models of Parkinson's disease.Hyeyoon Eo et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 117, 109184-109184 (2019-08-08)
Sympathetic nervous system controls resolution of inflammation via regulation of repulsive guidance molecule A.Andreas Körner et al.Nature communications, 10(1), 633-633 (2019-02-09)
Optostimulation of striatonigral terminals in substantia nigra induces dyskinesia that increases after L-DOPA in a mouse model of Parkinson's disease.Ettel Keifman et al.British journal of pharmacology, 176(13), 2146-2161 (2019-03-22)
Preclinical Comparison of Stem Cells Secretome and Levodopa Application in a 6-Hydroxydopamine Rat Model of Parkinson's Disease.Fábio G Teixeira et al.Cells, 9(2) (2020-02-06)
PET Imaging of Serotonin Transporters With 4-[(18)F]-ADAM in a Parkinsonian Rat Model With Porcine Neural Xenografts.Chuang-Hsin Chiu et al.Cell transplantation, 25(2), 301-311 (2015-05-23)
The hTH-GFP reporter rat model for the study of Parkinson's disease.Lorraine Iacovitti et al.PloS one, 9(12), e113151-e113151 (2014-12-03)
Preclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson Disease.Susanna Waters et al.The Journal of pharmacology and experimental therapeutics, 374(1), 113-125 (2020-05-03)
Silencing phosphodiesterase 7B gene by lentiviral-shRNA interference attenuates neurodegeneration and motor deficits in hemiparkinsonian mice.Jose A Morales-Garcia et al.Neurobiology of aging, 36(2), 1160-1173 (2014-12-03)
Identification of Critical Genes and miRNAs Associated with the Development of Parkinson's Disease.Jia Li et al.Journal of molecular neuroscience : MN, 65(4), 527-535 (2018-08-08)
Orbitofrontal or accumbens dopamine depletion does not affect risk-based decision making in rats.Bettina Mai et al.Cognitive, affective & behavioral neuroscience, 15(3), 507-522 (2015-04-11)
Exercise-induced rescue of tongue function without striatal dopamine sparing in a rat neurotoxin model of Parkinson disease.Michelle R Ciucci et al.Behavioural brain research, 252, 239-245 (2013-06-13)
Danshensu protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish.Cheong-Meng Chong et al.Neuroscience letters, 543, 121-125 (2013-04-09)
Loss of intestinal sympathetic innervation elicits an innate immune driven colitis.Rose A Willemze et al.Molecular medicine (Cambridge, Mass.), 25(1), 1-1 (2019-01-09)
α-synuclein overexpression in the retina leads to vision impairment and degeneration of dopaminergic amacrine cells.Elena Marrocco et al.Scientific reports, 10(1), 9619-9619 (2020-06-17)
Increased GABAergic transmission in neuropeptide Y-expressing neurons in the dopamine-depleted murine striatum.Lena Rubi et al.Journal of neurophysiology, 123(4), 1496-1503 (2020-03-12)
Nei-like 1 inhibition results in motor dysfunction and promotes inflammation in Parkinson's disease mice model.Bai Xue et al.Biochemical and biophysical research communications, 521(1), 245-251 (2019-10-28)
Impact of Aging on the 6-OHDA-Induced Rat Model of Parkinson's Disease.Sandra Barata-Antunes et al.International journal of molecular sciences, 21(10) (2020-05-20)
A widely distributed metalloenzyme class enables gut microbial metabolism of host- and diet-derived catechols.Vayu Maini Rekdal et al.eLife, 9 (2020-02-19)
Evolution of anti-parkinsonian activity of monoterpenoid (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in various in vivo models.Elena Valdman et al.European journal of pharmacology, 815, 351-363 (2017-09-25)
A DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine, exacerbates neurotoxicity and upregulates Parkinson's disease-related genes in dopaminergic neurons.Yong Wang et al.CNS neuroscience & therapeutics, 19(3), 183-190 (2013-02-28)
Impact of the Sensory and Sympathetic Nervous System on Fracture Healing in Ovariectomized Mice.Tanja Niedermair et al.International journal of molecular sciences, 21(2) (2020-01-16)
Neuroprotective Effect of Bergamot Juice in 6-OHDA-Induced SH-SY5Y Cell Death, an In Vitro Model of Parkinson's Disease.Nadia Ferlazzo et al.Pharmaceutics, 12(4) (2020-04-09)
Schisandrin B shows neuroprotective effect in 6-OHDA-induced Parkinson's disease via inhibiting the negative modulation of miR-34a on Nrf2 pathway.Qinghua Ba et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 75, 165-172 (2015-08-19)
Cellular and behavioral outcomes of dorsal striatonigral neuron ablation: new insights into striatal functions.Delphine Révy et al.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 39(11), 2662-2672 (2014-06-07)
Regenerative therapy in experimental parkinsonism: mixed population of differentiated mouse embryonic stem cells, rather than magnetically sorted and enriched dopaminergic cells provide neuroprotection.Debasmita Tripathy et al.CNS neuroscience & therapeutics, 20(8), 717-727 (2014-06-24)
Intrapallidal administration of 6-hydroxydopamine mimics in large part the electrophysiological and behavioral consequences of major dopamine depletion in the rat.P M Abedi et al.Neuroscience, 236, 289-297 (2013-02-05)
Novel Oxindole-Curcumin Hybrid Compound for Antioxidative Stress and Neuroprotection.Yoko Hirata et al.ACS chemical neuroscience, 11(1), 76-85 (2019-12-05)
Neuroprotective and neurorestorative activities of a novel iron chelator-brain selective monoamine oxidase-A/monoamine oxidase-B inhibitor in animal models of Parkinson's disease and aging.Orit Bar-Am et al.Neurobiology of aging, 36(3), 1529-1542 (2014-12-17)
Liver Growth Factor Induces Glia-Associated Neuroprotection in an In Vitro Model of Parkinson´s Disease.Rafael Gonzalo-Gobernado et al.Brain sciences, 10(5) (2020-05-28)
Characterizing motor and cognitive effects associated with deep brain stimulation in the GPi of hemi-Parkinsonian rats.Samantha R Summerson et al.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society, 22(6), 1218-1227 (2014-06-22)
Revealing Adenosine A2A-Dopamine D2 Receptor Heteromers in Parkinson's Disease Post-Mortem Brain through a New AlphaScreen-Based Assay.Víctor Fernández-Dueñas et al.International journal of molecular sciences, 20(14) (2019-07-26)
GDNF Promotes Survival and Therapeutic Efficacy of Human Adipose-Derived Mesenchymal Stem Cells in a Mouse Model of Parkinson's Disease.Shoujia Sun et al.Cell transplantation, 29, 963689720908512-963689720908512 (2020-04-16)
An activated sympathetic nervous system affects white adipocyte differentiation and lipolysis in a rat model of Parkinson's disease.XiangZhi Meng et al.Journal of neuroscience research, 93(2), 350-360 (2014-09-27)
Increased vulnerability of nigral dopamine neurons after expansion of their axonal arborization size through D2 dopamine receptor conditional knockout.Nicolas Giguère et al.PLoS genetics, 15(8), e1008352-e1008352 (2019-08-27)
Seaweeds' neuroprotective potential set in vitro on a human cellular stress model.Joana Silva et al.Molecular and cellular biochemistry, 473(1-2), 229-238 (2020-07-14)
Immature mDA neurons ameliorate motor deficits in a 6-OHDA Parkinson's disease mouse model and are functional after cryopreservation.Dominique Leitner et al.Stem cell research, 41, 101617-101617 (2019-11-16)
Perivascular Adipose Tissue Modulation of Neurogenic Vasorelaxation of Rat Mesenteric Arteries.Hsi-Hsien Chang et al.Journal of cardiovascular pharmacology, 75(1), 21-30 (2019-10-22)
Lesions of mediodorsal thalamic nucleus reverse abnormal firing of the medial prefrontal cortex neurons in parkinsonian rats.Ling-Ling Fan et al.Neural regeneration research, 14(9), 1635-1642 (2019-05-16)
Human autologous iPSC-derived dopaminergic progenitors restore motor function in Parkinson's disease models.Bin Song et al.The Journal of clinical investigation, 130(2), 904-920 (2019-11-13)
Repeated intrastriatal application of botulinum neurotoxin-A did not influence choline acetyltransferase-immunoreactive interneurons in hemiparkinsonian rat brain - A histological, stereological and correlational analysis.Alexander Hawlitschka et al.Brain research, 1742, 146877-146877 (2020-05-11)
Noradrenaline neuron degeneration contributes to motor impairments and development of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease.Eunju Shin et al.Experimental neurology, 257, 25-38 (2014-04-22)
Arachidonyl-2'-chloroethylamide (ACEA), a synthetic agonist of cannabinoid receptor, increases CB1R gene expression and reduces dyskinesias in a rat model of Parkinson's disease.Melissa Leija-Salazar et al.Pharmacology, biochemistry, and behavior, 194, 172950-172950 (2020-05-16)
ser31 Tyrosine hydroxylase phosphorylation parallels differences in dopamine recovery in nigrostriatal pathway following 6-OHDA lesion.Michael F Salvatore Journal of neurochemistry, 129(3), 548-558 (2014-01-15)
Brain-targeted intranasal delivery of dopamine with borneol and lactoferrin co-modified nanoparticles for treating Parkinson's disease.Shengnan Tang et al.Drug delivery, 26(1), 700-707 (2019-07-11)
Reversal of hyperactive subthalamic circuits differentially mitigates pain hypersensitivity phenotypes in parkinsonian mice.Yiwen Luan et al.Proceedings of the National Academy of Sciences of the United States of America, 117(18), 10045-10054 (2020-04-22)
L-DOPA-elicited abnormal involuntary movements in the rats damaged severely in substantia nigra by 6-hydroxydopamine.Rongfei Wang et al.Annals of palliative medicine, 9(3), 947-956 (2020-04-14)
Astrocytes in the rat nucleus tractus solitarii are critical for cardiovascular reflex control.Li-Hsien Lin et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(47), 18608-18617 (2013-11-22)
Innervating sympathetic neurons regulate heart size and the timing of cardiomyocyte cell cycle withdrawal.R E Kreipke et al.The Journal of physiology, 593(23), 5057-5073 (2015-10-01)
Functional Dopaminergic Neurons in Substantia Nigra are Required for Transcranial Magnetic Stimulation-Induced Motor Plasticity.Tsung-Hsun Hsieh et al.Cerebral cortex (New York, N.Y. : 1991), 25(7), 1806-1814 (2014-01-24)
Mice deficient in protein tyrosine phosphatase receptor type Z (PTPRZ) show reduced responsivity to methamphetamine despite an enhanced response to novelty.Akihiro Fujikawa et al.PloS one, 14(8), e0221205-e0221205 (2019-08-21)
Duration of drug action of dopamine D2 agonists in mice with 6-hydroxydopamine-induced lesions.Akihiro Tsuchioka et al.Neuroreport, 26(18), 1126-1132 (2015-11-13)
A potential target for the treatment of Parkinson's disease: effect of lateral habenula lesions.Bing Han et al.Parkinsonism & related disorders, 20(11), 1191-1195 (2014-09-16)
MiR-142-5p Protects Against 6-OHDA-Induced SH-SY5Y Cell Injury by Downregulating BECN1 and Autophagy.Jian Chen et al.Dose-response : a publication of International Hormesis Society, 18(1), 1559325820907016-1559325820907016 (2020-03-05)
Dopaminergic Contributions to Vocal Learning.Lukas A Hoffmann et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(7), 2176-2189 (2016-02-19)
Galantamine in rheumatoid arthritis: A cross talk of parasympathetic and sympathetic system regulates synovium-derived microRNAs and related pathogenic pathways.Mennatallah A Gowayed et al.European journal of pharmacology, 883, 173315-173315 (2020-07-06)
Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia.Nikhil Panicker et al.The Journal of experimental medicine, 216(6), 1411-1430 (2019-05-01)
A rat model of striatonigral degeneration generated by simultaneous injection of 6-hydroxydopamine into the medial forebrain bundle and quinolinic acid into the striatum.Hyung Ho Yoon et al.Journal of Korean medical science, 29(11), 1555-1561 (2014-11-20)
Protective effects of valproic acid on 6-hydroxydopamine-induced neuroinjury.Shih-Wei Hsu et al.Environmental toxicology, 35(8), 840-848 (2020-03-14)
Reciprocal cross-sensitization of D1 and D3 receptors following pharmacological stimulation in the hemiparkinsonian rat.Kathryn Lanza et al.Psychopharmacology, 237(1), 155-165 (2019-08-23)
Secretome of Undifferentiated Neural Progenitor Cells Induces Histological and Motor Improvements in a Rat Model of Parkinson's Disease.Bárbara Mendes-Pinheiro et al.Stem cells translational medicine, 7(11), 829-838 (2018-09-22)
17 β-Estradiol Oxidative Stress Attenuation and Autophagy-Induced Dopaminergic Neuroprotection.Roya Varmazyar et al.Cell journal, 21(1), 1-6 (2018-12-07)
Evaluation of 18F-IAM6067 as a sigma-1 receptor PET tracer for neurodegeneration in vivo in rodents and in human tissue.François-Xavier Lepelletier et al.Theranostics, 10(18), 7938-7955 (2020-07-30)
Neuronal activity in the medial associative-limbic and lateral motor part of the rat subthalamic nucleus and the effect of 6-hydroxydopamine-induced lesions of the dorsolateral striatum.Christoph Lindemann et al.The Journal of comparative neurology, 521(14), 3226-3240 (2013-06-22)
Upregulation of neuronal astrocyte elevated gene-1 protects nigral dopaminergic neurons in vivo.Eunju Leem et al.Cell death & disease, 9(5), 449-449 (2018-04-20)
Temporal development of behavioral impairments in rats following locus coeruleus lesion induced by 6-hydroxydopamine: Involvement of β3-adrenergic receptors.Tuane Bazanella Sampaio et al.Neuropharmacology, 151, 98-111 (2019-04-09)
Metformin regulates astrocyte reactivity in Parkinson's disease and normal aging.Young-Kyoung Ryu et al.Neuropharmacology, 175, 108173-108173 (2020-06-05)
p-Chloroamphetamine-Enhanced Neostriatal Dopamine Exocytosis in Rats Neonatally Co-lesioned with 6-OHDA and 5,7-DHT: Relevance to Parkinson's Disease.John P Kostrzewa et al.Neurotoxicity research, 37(3), 543-552 (2020-01-16)
PINK1/parkin-mediated mitophagy pathway is related to neuroprotection by carnosic acid in SH-SY5Y cells.Chia-Yuan Lin et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 125, 430-437 (2019-02-02)
Lipophilic ferulic acid derivatives protect PC12 cells against oxidative damage via modulating β-amyloid aggregation and activating Nrf2 enzymes.Yu Wu et al.Food & function, 11(5), 4707-4718 (2020-05-16)
The Substantia Nigra Is Permissive and Gains Inductive Signals When Lesioned for Dopaminergic Differentiation of Embryonic Stem Cells.Omar Collazo-Navarrete et al.Stem cells and development, 28(16), 1104-1115 (2019-05-30)
Effects of Cardiac Sympathetic Neurodegeneration and PPARγ Activation on Rhesus Macaque Whole Blood miRNA and mRNA Expression Profiles.Jeanette M Metzger et al.BioMed research international, 2020, 9426204-9426204 (2020-05-29)
Relationship between dopamine deficit and the expression of depressive behavior resulted from alteration of serotonin system.Minkyung Lee et al.Synapse (New York, N.Y.), 69(9), 453-460 (2015-06-20)
Increased P2X7 Receptor Binding Is Associated With Neuroinflammation in Acute but Not Chronic Rodent Models for Parkinson's Disease.Melissa Crabbé et al.Frontiers in neuroscience, 13, 799-799 (2019-08-17)
Multi-targeting aurones with monoamine oxidase and amyloid-beta inhibitory activities: Structure-activity relationship and translating multi-potency to neuroprotection.Kok-Fui Liew et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 110, 118-128 (2018-11-23)
Dopamine transporter loss in 6-OHDA Parkinson's model is unmet by parallel reduction in dopamine uptake.Tanya Chotibut et al.PloS one, 7(12), e52322-e52322 (2013-01-10)
The degeneration of dopaminergic synapses in Parkinson's disease: A selective animal model.Ingrid Morales et al.Behavioural brain research, 289, 19-28 (2015-04-25)
Reduced reach-related modulation of motor thalamus neural activity in a rat model of Parkinson's disease.Clémentine Bosch-Bouju et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(48), 15836-15850 (2014-11-28)
Dexamethasone Causes Hypertension in Rats Even Under Chemical Blockade of Peripheral Sympathetic Nerves.Alexandra E Soto-Piña et al.Frontiers in neuroscience, 13, 1305-1305 (2019-12-24)
Intrastriatal administration of coenzyme Q10 enhances neuroprotection in a Parkinson's disease rat model.Hyung Woo Park et al.Scientific reports, 10(1), 9572-9572 (2020-06-14)
Effects of carvacrol and physical exercise on motor and memory impairments associated with Parkinson's disease.Leila Hamzehloei et al.Arquivos de neuro-psiquiatria, 77(7), 493-500 (2019-08-01)
Pharmacological antagonism of histamine H2R ameliorated L-DOPA-induced dyskinesia via normalization of GRK3 and by suppressing FosB and ERK in PD.Mohamed Rafiuddin Ahmed et al.Neurobiology of aging, 81, 177-189 (2019-07-16)
Valproate is protective against 6-OHDA-induced dopaminergic neurodegeneration in rodent midbrain: A potential role of BDNF up-regulation.Ching-Long Lai et al.Journal of the Formosan Medical Association = Taiwan yi zhi, 118(1 Pt 3), 420-428 (2018-07-23)
Rebamipide Mitigates Impairments in Mitochondrial Function and Bioenergetics with α-Synuclein Pathology in 6-OHDA-Induced Hemiparkinson's Model in Rats.Akanksha Mishra et al.Neurotoxicity research, 35(3), 542-562 (2019-01-06)
Nitroxide Radical-Containing Redox Nanoparticles Protect Neuroblastoma SH-SY5Y Cells against 6-Hydroxydopamine Toxicity.Monika Pichla et al.Oxidative medicine and cellular longevity, 2020, 9260748-9260748 (2020-05-08)
Selective Induction of Human Autonomic Neurons Enables Precise Control of Cardiomyocyte Beating.Yuzo Takayama et al.Scientific reports, 10(1), 9464-9464 (2020-06-13)
Role of the locus coeruleus catecholaminergic neurons in the chemosensory control of breathing in a Parkinson's disease model.Luiz M Oliveira et al.Experimental neurology, 293, 172-180 (2017-04-23)
A non-cholinergic neuronal loss in the pedunculopontine nucleus of toxin-evoked parkinsonian rats.Ilse S Pienaar et al.Experimental neurology, 248, 213-223 (2013-06-19)
Angiotensin II induces oxidative stress and upregulates neuroprotective signaling from the NRF2 and KLF9 pathway in dopaminergic cells.Juan A Parga et al.Free radical biology & medicine, 129, 394-406 (2018-10-14)
Rho kinase inhibition by fasudil in the striatal 6-hydroxydopamine lesion mouse model of Parkinson disease.Lars Tatenhorst et al.Journal of neuropathology and experimental neurology, 73(8), 770-779 (2014-07-09)
Comprehensive Analysis of Neurotoxin-Induced Ablation of Dopaminergic Neurons in Zebrafish Larvae.Michael Kalyn et al.Biomedicines, 8(1) (2020-01-08)
Propagation of beta/gamma rhythms in the cortico-basal ganglia circuits of the parkinsonian rat.Timothy O West et al.Journal of neurophysiology, 119(5), 1608-1628 (2018-01-24)
6-Hydroxydopamine induces secretion of PARK7/DJ-1 via autophagy-based unconventional secretory pathway.Yasuomi Urano et al.Autophagy, 14(11), 1943-1958 (2018-08-17)
The impact of ventral noradrenergic bundle lesions on increased IL-1 in the PVN and hormonal responses to stress in male sprague dawley rats.Peter Blandino et al.Endocrinology, 154(7), 2489-2500 (2013-05-15)
Delta oscillations are a robust biomarker of dopamine depletion severity and motor dysfunction in awake mice.Timothy C Whalen et al.Journal of neurophysiology, 124(2), 312-329 (2020-06-25)
Selective effects of dopamine depletion and L-DOPA therapy on learning-related firing dynamics of striatal neurons.Ledia F Hernandez et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(11), 4782-4795 (2013-03-15)
Adenosine A1 receptor stimulation reduces D1 receptor-mediated GABAergic transmission from striato-nigral terminals and attenuates l-DOPA-induced dyskinesia in dopamine-denervated mice.Dalila Mango et al.Experimental neurology, 261, 733-743 (2014-09-01)
Hyperpolarization of the subthalamic nucleus alleviates hyperkinetic movement disorders.Chun-Hwei Tai et al.Scientific reports, 10(1), 8278-8278 (2020-05-20)
Control of Adipocyte Thermogenesis and Lipogenesis through β3-Adrenergic and Thyroid Hormone Signal Integration.Adilson Guilherme et al.Cell reports, 31(5), 107598-107598 (2020-05-07)
Study on antrodia camphorata polysaccharide in alleviating the neuroethology of PD mice by decreasing the expression of NLRP3 inflammasome.Chenyang Han et al.Phytotherapy research : PTR, 33(9), 2288-2297 (2019-07-31)
The α7 nicotinic receptor agonist ABT-107 protects against nigrostriatal damage in rats with unilateral 6-hydroxydopamine lesions.Tanuja Bordia et al.Experimental neurology, 263, 277-284 (2014-09-28)
miR-21 may Act as a Potential Mediator Between Inflammation and Abnormal Bone Formation in Ankylosing Spondylitis Based on TNF-α Concentration-Dependent Manner Through the JAK2/STAT3 Pathway.Yu-Cong Zou et al.Dose-response : a publication of International Hormesis Society, 18(1), 1559325819901239-1559325819901239 (2020-02-06)
Nose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease.Subrat K Bhattamisra et al.International journal of pharmaceutics, 579, 119148-119148 (2020-02-23)
Tetramethylpyrazine Analogue T-006 Exerts Neuroprotective Effects against 6-Hydroxydopamine-Induced Parkinson's Disease In Vitro and In Vivo.Hefeng Zhou et al.Oxidative medicine and cellular longevity, 2019, 8169125-8169125 (2019-12-13)
Short- and long-term unilateral 6-hydroxydopamine lesions in rats show different changes in characteristics of spontaneous firing of substantia nigra pars reticulata neurons.Sonja Seeger-Armbruster et al.Experimental brain research, 224(1), 15-24 (2013-01-04)
Translocator Protein Ligand Protects against Neurodegeneration in the MPTP Mouse Model of Parkinsonism.Jing Gong et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(19), 3752-3769 (2019-02-24)
Effects of local activation and blockade of dopamine D4 receptors in the spiking activity of the reticular thalamic nucleus in normal and in ipsilateral dopamine-depleted rats.R Barrientos et al.Brain research, 1712, 34-46 (2019-02-05)
Sympathetic Nerves Positively Regulate Eosinophil-Driven Allergic Conjunctivitis via α1-Adrenergic Receptor Signaling.Jun Liu et al.The American journal of pathology, 190(6), 1298-1308 (2020-03-21)
The highly selective mGlu2 receptor positive allosteric modulator LY-487,379 alleviates l-DOPA-induced dyskinesia in the 6-OHDA-lesioned rat model of Parkinson's disease.Adjia Hamadjida et al.The European journal of neuroscience, 51(12), 2412-2422 (2020-01-17)
Safinamide inhibits in vivo glutamate release in a rat model of Parkinson's disease.Clarissa A Pisanò et al.Neuropharmacology, 167, 108006-108006 (2020-02-23)
CREB1-driven expression of miR-320a promotes mitophagy by down-regulating VDAC1 expression during serum starvation in cervical cancer cells.Qin-Qin Li et al.Oncotarget, 6(33), 34924-34940 (2015-10-17)
Alterations of the gut microbiota with antibiotics protects dopamine neuron loss and improve motor deficits in a pharmacological rodent model of Parkinson's disease.Dimitri N Koutzoumis et al.Experimental neurology, 325, 113159-113159 (2019-12-18)
Protective effects of β- nicotinamide adenine dinucleotide against motor deficits and dopaminergic neuronal damage in a mouse model of Parkinson's disease.Chang Shan et al.Progress in neuro-psychopharmacology & biological psychiatry, 94, 109670-109670 (2019-06-21)
Overexpression of α-synuclein simultaneously increases glutamate NMDA receptor phosphorylation and reduces glucocerebrosidase activity.Junfeng Yang et al.Neuroscience letters, 611, 51-58 (2015-11-28)
Chondroitinase ABC reduces dopaminergic nigral cell death and striatal terminal loss in a 6-hydroxydopamine partial lesion mouse model of Parkinson's disease.Edward J R Fletcher et al.BMC neuroscience, 20(1), 61-61 (2019-12-22)
Neuronal modulation of hepatic lipid accumulation induced by bingelike drinking.Maria Ibars et al.American journal of physiology. Endocrinology and metabolism, 318(5), E655-E666 (2020-02-12)
A DJ-1 Based Peptide Attenuates Dopaminergic Degeneration in Mice Models of Parkinson's Disease via Enhancing Nrf2.Nirit Lev et al.PloS one, 10(5), e0127549-e0127549 (2015-05-30)
G-protein coupled receptor 6 deficiency alters striatal dopamine and cAMP concentrations and reduces dyskinesia in a mouse model of Parkinson's disease.Patrick Oeckl et al.Experimental neurology, 257, 1-9 (2014-04-22)
The ameliorative effect of Monascus purpureus NTU 568-fermented rice extracts on 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells and the rat model of Parkinson's disease.Wei-Ting Tseng et al.Food & function, 7(2), 752-762 (2016-01-27)
Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson's disease models.Xu-Xu Zhuang et al.Cell death & disease, 11(2), 128-128 (2020-02-20)
Design and evaluation of bi-functional iron chelators for protection of dopaminergic neurons from toxicants.Simon Gutbier et al.Archives of toxicology, 94(9), 3105-3123 (2020-07-02)
Ceruloplasmin is Involved in the Nigral Iron Accumulation of 6-OHDA-Lesioned Rats.Jun Wang et al.Cellular and molecular neurobiology, 35(5), 661-668 (2015-02-07)
Ventromedial prefrontal cortex is involved in preference and hedonic evaluation of tastes.Beáta Berta et al.Behavioural brain research, 367, 149-157 (2019-04-04)
Extracellular Nanomatrix-Induced Self-Organization of Neural Stem Cells into Miniature Substantia Nigra-Like Structures with Therapeutic Effects on Parkinsonian Rats.Shiqing Zhang et al.Advanced science (Weinheim, Baden-Wurttemberg, Germany), 6(24), 1901822-1901822 (2019-12-25)
Stress-elicited glucocorticoid receptor signaling upregulates TIGIT in innate-like invariant T lymphocytes.Patrick T Rudak et al.Brain, behavior, and immunity, 80, 793-804 (2019-05-21)
Neuroprotective Mechanisms of Three Natural Antioxidants on a Rat Model of Parkinson's Disease: A Comparative Study.Lyubka P Tancheva et al.Antioxidants (Basel, Switzerland), 9(1) (2020-01-16)
The octadecaneuropeptide ODN prevents 6-hydroxydopamine-induced apoptosis of cerebellar granule neurons through a PKC-MAPK-dependent pathway.Hadhemi Kaddour et al.Journal of neurochemistry, 125(4), 620-633 (2013-01-05)
Metformin as a protective agent against natural or chemical toxicities: a comprehensive review on drug repositioning.S E Meshkani et al.Journal of endocrinological investigation, 43(1), 1-19 (2019-05-18)
Unilateral accumbal dopamine depletion affects decision-making in a side-specific manner.A M Cunha et al.Experimental neurology, 327, 113221-113221 (2020-02-07)
The Bacterial Toxin CNF1 Protects Human Neuroblastoma SH-SY5Y Cells against 6-Hydroxydopamine-Induced Cell Damage: The Hypothesis of CNF1-Promoted Autophagy as an Antioxidant Strategy.Sara Travaglione et al.International journal of molecular sciences, 21(9) (2020-05-15)
Characteristic response of striatal astrocytes to dopamine depletion.Yao-Feng Zhu et al.Neural regeneration research, 15(4), 724-730 (2019-10-23)
Docosahexaenoic acid protects motor function and increases dopamine synthesis in a rat model of Parkinson's disease via mechanisms associated with increased protein kinase activity in the striatum.Neha Milind Chitre et al.Neuropharmacology, 167, 107976-107976 (2020-02-01)
Secreted miR-34a in astrocytic shedding vesicles enhanced the vulnerability of dopaminergic neurons to neurotoxins by targeting Bcl-2.Susu Mao et al.Protein & cell, 6(7), 529-540 (2015-06-21)
The balance of striatal feedback transmission is disrupted in a model of parkinsonism.Violeta G López-Huerta et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(11), 4964-4975 (2013-03-15)
Propolis as A Potential Disease-Modifying Strategy in Parkinson's Disease: Cardioprotective and Neuroprotective Effects in the 6-OHDA Rat Model.Valeria C Gonçalves et al.Nutrients, 12(6) (2020-05-30)
GABAA-receptor activation in the subthalamic nucleus compensates behavioral asymmetries in the hemiparkinsonian rat.David Petri et al.Behavioural brain research, 252, 58-67 (2013-06-04)
Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia.Tim Fieblinger et al.Nature communications, 5, 5316-5316 (2014-11-02)
Activated cathepsin L is associated with the switch from autophagy to apoptotic death of SH-SY5Y cells exposed to 6-hydroxydopamine.Lingyun Li et al.Biochemical and biophysical research communications, 470(3), 579-585 (2016-01-23)
Novel design of (PEG-ylated)PAMAM-based nanoparticles for sustained delivery of BDNF to neurotoxin-injured differentiated neuroblastoma cells.Maria Dąbkowska et al.Journal of nanobiotechnology, 18(1), 120-120 (2020-09-02)
6-Hydroxydopamine impairs mitochondrial function in the rat model of Parkinson's disease: respirometric, histological, and behavioral analyses.Andreas Kupsch et al.Journal of neural transmission (Vienna, Austria : 1996), 121(10), 1245-1257 (2014-03-15)
Allopregnanolone Modulates GABAAR-Dependent CaMKIIδ3 and BDNF to Protect SH-SY5Y Cells Against 6-OHDA-Induced Damage.Tongtong Wang et al.Frontiers in cellular neuroscience, 13, 569-569 (2020-01-31)
Benzodiazepinone derivatives protect against endoplasmic reticulum stress-mediated cell death in human neuronal cell lines.Haixia Zou et al.ACS chemical neuroscience, 6(3), 464-475 (2014-12-30)
Role of the sympathetic nervous system in carbon tetrachloride-induced hepatotoxicity and systemic inflammation.Jung-Chun Lin et al.PloS one, 10(3), e0121365-e0121365 (2015-03-24)
Feeding-produced subchronic high plasma levels of uric acid improve behavioral dysfunction in 6-hydroxydopamine-induced mouse model of Parkinson's disease.Akio Nakashima et al.Behavioural pharmacology, 30(1), 89-94 (2018-05-31)
Dysregulated Long Non-coding RNAs in Parkinson's Disease Contribute to the Apoptosis of Human Neuroblastoma Cells.Yun Fan et al.Frontiers in neuroscience, 13, 1320-1320 (2020-01-11)
Serotonin1A receptors in the dorsal hippocampus regulate working memory and long-term habituation in the hemiparkinsonian rats.Ye Liu et al.Behavioural brain research, 376, 112207-112207 (2019-09-03)
Beneficial effects of cysteamine in Thy1-α-Syn mice and induced pluripotent stem cells with a SNCA gene triplication.Alberto Siddu et al.Neurobiology of disease, 145, 105042-105042 (2020-08-18)
Novel Striatal GABAergic Interneuron Populations Labeled in the 5HT3a(EGFP) Mouse.A B Muñoz-Manchado et al.Cerebral cortex (New York, N.Y. : 1991), 26(1), 96-105 (2014-08-26)
NRF2 Regulates PINK1 Expression under Oxidative Stress Conditions.Hitoshi Murata et al.PloS one, 10(11), e0142438-e0142438 (2015-11-12)
Effect of stromal cell-derived factor-1/CXCR4 axis in neural stem cell transplantation for Parkinson's disease.Jiao-Tian Xu et al.Neural regeneration research, 15(1), 112-119 (2019-09-20)
Origin and Function of Stress-Induced IL-6 in Murine Models.Hua Qing et al.Cell, 182(2), 372-387 (2020-07-02)
Gastrointestinal non-motor dysfunction in Parkinson's disease model rats with 6-hydroxydopamine.Xiao-Yan Feng et al.Physiological research, 68(2), 295-303 (2019-01-11)
Neuroprotective and neurogenic effects of novel tetramethylpyrazine derivative T-006 in Parkinson's disease models through activating the MEF2-PGC1α and BDNF/CREB pathways.Haiyun Chen et al.Aging, 12(14), 14897-14917 (2020-07-28)
Synaptic zinc contributes to motor and cognitive deficits in 6-hydroxydopamine mouse models of Parkinson's disease.Joanna Sikora et al.Neurobiology of disease, 134, 104681-104681 (2019-11-24)
Neuroprotective effects of oral gallic acid against oxidative stress induced by 6-hydroxydopamine in rats.Mohammad Taghi Mansouri et al.Food chemistry, 138(2-3), 1028-1033 (2013-02-16)
Molecular mechanisms of 6-hydroxydopamine-induced cytotoxicity in PC12 cells: involvement of hydrogen peroxide-dependent and-independent actionSaito Y, et al. Free Radical Biology & Medicine, 42(5), 675-685 (2007)
In Vivo Phenotyping of Familial Parkinson's Disease with Human Induced Pluripotent Stem Cells: A Proof-of-Concept Study.Ourania Zygogianni et al.Neurochemical research, 44(6), 1475-1493 (2019-04-17)
Up-regulation of microRNA-375 ameliorates the damage of dopaminergic neurons, reduces oxidative stress and inflammation in Parkinson's disease by inhibiting SP1.Li-Jun Cai et al.Aging, 12(1), 672-689 (2020-01-14)
Betanin Attenuates Oxidative Stress Induced by 6-OHDA in PC12 Cells via SAPK/JNK and PI3 K Pathways.Elham Hadipour et al.Neurochemical research, 45(2), 395-403 (2019-12-21)
The majority of newly generated cells in the adult mouse substantia nigra express low levels of Doublecortin, but their proliferation is unaffected by 6-OHDA-induced nigral lesion or Minocycline-mediated inhibition of neuroinflammation.Maik M A Worlitzer et al.The European journal of neuroscience, 38(5), 2684-2692 (2013-06-06)
Performance of movement in hemiparkinsonian rats influences the modifications induced by dopamine agonists in striatal efferent dynorphinergic neurons.Lucia Frau et al.Experimental neurology, 247, 663-672 (2013-03-19)
The protective effect of inosine against rotenone-induced Parkinson's disease in mice; role of oxido-nitrosative stress, ERK phosphorylation, and A2AR expression.Marwa E A El-Shamarka et al.Naunyn-Schmiedeberg's archives of pharmacology, 393(6), 1041-1053 (2020-01-10)
Combination of Human Mesenchymal Stem Cells and Repetitive Transcranial Magnetic Stimulation Enhances Neurological Recovery of 6-Hydroxydopamine Model of Parkinsonian's Disease.Ji Yong Lee et al.Tissue engineering and regenerative medicine, 17(1), 67-80 (2020-01-24)
Probucol affords neuroprotection in a 6-OHDA mouse model of Parkinson's disease.Renata Pietsch Ribeiro et al.Neurochemical research, 38(3), 660-668 (2013-01-22)
Neuroprotective activity of Stereospermum suaveolens DC against 6-OHDA induced Parkinson's disease model.M H Shalavadi et al.Indian journal of pharmacology, 44(6), 737-743 (2012-12-19)
Sensation of TRPV1 via 5-hydroxytryptamine signaling modulates pain hypersensitivity in a 6-hydroxydopamine induced mice model of Parkinson's disease.Man Li et al.Biochemical and biophysical research communications, 521(4), 868-873 (2019-11-12)
Lipoamide Ameliorates Oxidative Stress via Induction of Nrf2/ARE Signaling Pathway in PC12 Cells.Yanan Hou et al.Journal of agricultural and food chemistry, 67(29), 8227-8234 (2019-07-13)
Growth/differentiation factor-15 deficiency compromises dopaminergic neuron survival and microglial response in the 6-hydroxydopamine mouse model of Parkinson's disease.Venissa Machado et al.Neurobiology of disease, 88, 1-15 (2016-01-07)
Glycine transporter-1 inhibition promotes striatal axon sprouting via NMDA receptors in dopamine neurons.Yvonne Schmitz et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(42), 16778-16789 (2013-10-18)
Salsolinol-neurotoxic or Neuroprotective?Magdalena Kurnik-Łucka et al.Neurotoxicity research, 37(2), 286-297 (2019-11-17)
Partial depletion of dopaminergic neurons in the substantia nigra impairs olfaction and alters neural activity in the olfactory bulb.Wenfeng Zhang et al.Scientific reports, 9(1), 254-254 (2019-01-24)
Neurotensin-polyplex-mediated brain-derived neurotrophic factor gene delivery into nigral dopamine neurons prevents nigrostriatal degeneration in a rat model of early Parkinson's disease.Nancy G Hernandez-Chan et al.Journal of biomedical science, 22, 59-59 (2015-07-23)
Effects on goal directed behavior and habit in two animal models of Parkinson's disease.Inmaculada Márquez et al.Neurobiology of learning and memory, 169, 107190-107190 (2020-02-15)
Anti-oxidation and Antiapoptotic Effects of Chondroitin Sulfate on 6-Hydroxydopamine-Induced Injury Through the Up-Regulation of Nrf2 and Inhibition of Mitochondria-Mediated Pathway.Chuanxia Ju et al.Neurochemical research, 40(7), 1509-1519 (2015-06-03)
Intraventricular administration of endoneuraminidase-N facilitates ectopic migration of subventricular zone-derived neural progenitor cells into 6-OHDA lesioned striatum of mice.Chen Li et al.Experimental neurology, 277, 139-149 (2016-01-03)
Modeling fall propensity in Parkinson's disease: deficits in the attentional control of complex movements in rats with cortical-cholinergic and striatal-dopaminergic deafferentation.Aaron Kucinski et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(42), 16522-16539 (2013-10-18)
GluN2D-containing NMDA receptors inhibit neurotransmission in the mouse striatum through a cholinergic mechanism: implication for Parkinson's disease.Xiaoqun Zhang et al.Journal of neurochemistry, 129(4), 581-590 (2014-01-31)
Optostimulation of striatonigral terminals in substantia nigra induces dyskinesia that increases after L-DOPA in a mouse model of Parkinson's disease.Ettel Keifman et al.British journal of pharmacology, 176(13), 2146-2161 (2019-03-22)
Dopamine D1 receptor agonism induces dynamin related protein-1 inhibition to improve mitochondrial biogenesis and dopaminergic neurogenesis in rat model of Parkinson's disease.Akanksha Mishra et al.Behavioural brain research, 378, 112304-112304 (2019-10-19)
Neuroprotective effect and mechanism of baicalin on Parkinson's disease model induced by 6-OHDA.Li Tu et al.Neuropsychiatric disease and treatment, 15, 3615-3625 (2020-02-27)
Eltoprazine prevents levodopa-induced dyskinesias by reducing causal interactions for theta oscillations in the dorsolateral striatum and substantia nigra pars reticulate.Qiang Wang et al.Neuropharmacology, 148, 1-10 (2019-01-07)
Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression.Peter Reinhardt et al.Cell stem cell, 12(3), 354-367 (2013-03-12)
A new dopaminergic nigro-olfactory projection.Günter U Höglinger et al.Acta neuropathologica, 130(3), 333-348 (2015-06-15)
Serum- and Glucocorticoid-Inducible Kinase 1 Confers Protection in Cell-Based and in In Vivo Neurotoxin Models via the c-Jun N-Terminal Kinase Signaling Pathway.Sarah Iqbal et al.Molecular and cellular biology, 35(11), 1992-2006 (2015-04-01)
Three-Dimensional Electron Microscopy Reconstruction of Degenerative Dopaminergic Neurons Surrounded by Activated Microglia in Substantia Nigra.Kazuhiko Nakadate et al.Ultrastructural pathology, 39(6), 369-377 (2015-06-26)
Inhibition of Mitochondrial Clearance and Cu/Zn-SOD Activity Enhance 6-Hydroxydopamine-Induced Neuronal Apoptosis.Sua In et al.Molecular neurobiology, 53(1), 777-791 (2015-01-30)
The longitudinal transcriptomic response of the substantia nigra to intrastriatal 6-hydroxydopamine reveals significant upregulation of regeneration-associated genes.Nicholas M Kanaan et al.PloS one, 10(5), e0127768-e0127768 (2015-05-21)
Cholinergic Interneurons Amplify Thalamostriatal Excitation of Striatal Indirect Pathway Neurons in Parkinson's Disease Models.Asami Tanimura et al.Neuron, 101(3), 444-458 (2019-01-20)
Differential effects of vagus nerve stimulation paradigms guide clinical development for Parkinson's disease.Ariana Q Farrand et al.Brain stimulation, 13(5), 1323-1332 (2020-07-07)
Unraveling the Role of Astrocytes in Subthalamic Nucleus Deep Brain Stimulation in a Parkinson's Disease Rat Model.Ana Carolina Pinheiro Campos et al.Cellular and molecular neurobiology, 40(6), 939-954 (2020-01-16)
Selective Regulation of 5-HT1B Serotonin Receptor Expression in the Striatum by Dopamine Depletion and Repeated L-DOPA Treatment: Relationship to L-DOPA-Induced Dyskinesias.Fernando E Padovan-Neto et al.Molecular neurobiology, 57(2), 736-751 (2019-08-31)
Calpain mediated expansion of CD4+ cytotoxic T cells in rodent models of Parkinson's disease.Azizul Haque et al.Experimental neurology, 330, 113315-113315 (2020-04-18)
Stimulus-dependent neuronal cell responses in SH-SY5Y neuroblastoma cells.Xiguang Sun et al.Molecular medicine reports, 13(3), 2215-2220 (2016-01-20)
Unaltered retinal dopamine levels in a C57BL/6 mouse model of form-deprivation myopia.Xiao-Hua Wu et al.Investigative ophthalmology & visual science, 56(2), 967-977 (2015-01-22)
Spatial distribution of 5-hydroxymethyl cytosine in rat brain and temporal distribution in striatum.Tingting Zheng et al.Neurochemical research, 40(4), 688-697 (2015-02-04)
Effects of catecholaminergic nerve lesion on endometrial development during early pregnancy in Mice.Yulan Dong et al.Histology and histopathology, 31(4), 415-424 (2015-11-12)
The Effect of Human Umbilical Cord Mesenchymal Stromal Cells in Protection of Dopaminergic Neurons from Apoptosis by Reducing Oxidative Stress in the Early Stage of a 6-OHDA-Induced Parkinson's Disease Model.Heng Chi et al.Cell transplantation, 28(1_suppl), 87S-99S (2019-11-30)
Transient neuroprotection by SRY upregulation in dopamine cells following injury in males.Daniel P Czech et al.Endocrinology, 155(7), 2602-2612 (2014-04-09)
Aberrant Tonic Inhibition of Dopaminergic Neuronal Activity Causes Motor Symptoms in Animal Models of Parkinson's Disease.Jun Young Heo et al.Current biology : CB, 30(2), 276-291 (2020-01-14)
Shared cerebral metabolic pathology in non-transgenic animal models of Alzheimer's and Parkinson's disease.Jelena Osmanovic Barilar et al.Journal of neural transmission (Vienna, Austria : 1996), 127(2), 231-250 (2020-02-08)
PAX6 expression may be protective against dopaminergic cell loss in Parkinson's disease.Meghan G Thomas et al.CNS & neurological disorders drug targets, 15(1), 73-79 (2015-08-22)
Inhibiting subthalamic D5 receptor constitutive activity alleviates abnormal electrical activity and reverses motor impairment in a rat model of Parkinson's disease.Jonathan Chetrit et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(37), 14840-14849 (2013-09-13)
Melatonin is protective against 6-hydroxydopamine-induced oxidative stress in a hemiparkinsonian rat model.O Ozsoy et al.Free radical research, 49(8), 1004-1014 (2015-03-21)
Parkin represses 6-hydroxydopamine-induced apoptosis via stabilizing scaffold protein p62 in PC12 cells.Xiao-ou Hou et al.Acta pharmacologica Sinica, 36(11), 1300-1307 (2015-09-15)
(6aR)-11-amino-N-propyl-noraporphine, a new dopamine D2 and serotonin 5-HT1A dual agonist, elicits potent antiparkinsonian action and attenuates levodopa-induced dyskinesia in a 6-OHDA-lesioned rat model of Parkinson's disease.Rui Zhao et al.Pharmacology, biochemistry, and behavior, 124, 204-210 (2014-06-24)
Pre-administration of BAX-inhibiting peptides decrease the loss of the nigral dopaminergic neurons in rats.Chi Ma et al.Life sciences, 144, 113-120 (2015-11-28)
Design and synthesis of highly potent and isoform selective JNK3 inhibitors: SAR studies on aminopyrazole derivatives.Ke Zheng et al.Journal of medicinal chemistry, 57(23), 10013-10030 (2014-11-14)
Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's disease.Pingping Song et al.Protein & cell, 7(2), 114-129 (2016-01-10)
Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis.Felipe Henriques et al.Cell reports, 32(5), 107998-107998 (2020-08-07)
Acetylcholinesterase inhibitory activity and neuroprotection in vitro, molecular docking, and improved learning and memory functions of demethylcurcumin in scopolamine-induced amnesia ICR mice.Yuh-Hwa Liu et al.Food & function, 11(3), 2328-2338 (2020-03-03)
Adaptation within mitochondrial oxidative phosphorylation supercomplexes and membrane viscosity during degeneration of dopaminergic neurons in an animal model of early Parkinson's disease.Katarzyna Kuter et al.Biochimica et biophysica acta, 1862(4), 741-753 (2016-02-05)
Role of nucleus of the solitary tract noradrenergic neurons in post-stress cardiovascular and hormonal control in male rats.Jana Bundzikova-Osacka et al.Stress (Amsterdam, Netherlands), 18(2), 221-232 (2015-03-15)
Antimicrobial Peptide, Lumbricusin, Ameliorates Motor Dysfunction and Dopaminergic Neurodegeneration in a Mouse Model of Parkinson's Disease.Dae Hong Kim et al.Journal of microbiology and biotechnology, 25(10), 1640-1647 (2015-07-29)
Buspirone requires the intact nigrostriatal pathway to reduce the activity of the subthalamic nucleus via 5-HT1A receptors.A Sagarduy et al.Experimental neurology, 277, 35-45 (2015-12-22)
Neuroprotective Effect of Optimized Yinxieling Formula in 6-OHDA-Induced Chronic Model of Parkinson's Disease through the Inflammation Pathway.Renrong Wei et al.Evidence-based complementary and alternative medicine : eCAM, 2019, 2529641-2529641 (2020-01-14)
mitoLUHMES: An Engineered Neuronal Cell Line for the Analysis of the Motility of Mitochondria.Tomasz M Stępkowski et al.Cellular and molecular neurobiology, 37(6), 1055-1066 (2016-11-11)
Regulation of dopamine neurotransmission from serotonergic neurons by ectopic expression of the dopamine D2 autoreceptor blocks levodopa-induced dyskinesia.Rhyomi C Sellnow et al.Acta neuropathologica communications, 7(1), 8-8 (2019-01-17)
Cortical stimulation relieves parkinsonian pathological activity in vitro.Ariadna Aparicio-Juárez et al.The European journal of neuroscience, 49(6), 834-848 (2017-12-19)
The macrocyclic lactones ivermectin and moxidectin show differential effects on rotational behavior in the 6-hydroxydopamine mouse model of Parkinson's disease.Alicia M P Warnecke et al.Behavioural brain research, 393, 112804-112804 (2020-07-16)
Serotonergic system in hypoxic ventilatory response in unilateral rat model of Parkinson's disease.Kryspin Andrzejewski et al.Journal of biomedical science, 24(1), 24-24 (2017-03-30)
Orbitofrontal dopamine depletion upregulates caudate dopamine and alters behavior via changes in reinforcement sensitivity.H F Clarke et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(22), 7663-7676 (2014-05-30)
Asymmetrical response of aminopeptidase A in the medial prefrontal cortex and striatum of 6-OHDA-unilaterally-lesioned Wistar Kyoto and spontaneously hypertensive rats.Inmaculada Banegas et al.Pharmacology, biochemistry, and behavior, 182, 12-21 (2019-05-28)
Procyanidin protects against 6-hydroxydopamine-induced dopaminergic neuron damage via the regulation of the PI3K/Akt signalling pathway.Ying Zhang et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 114, 108789-108789 (2019-03-30)
Kv7.2 subunit-containing M-type potassium channels in the lateral habenula are involved in the regulation of working memory in parkinsonian rats.Guanyun Bian et al.Neuropharmacology, 168, 108012-108012 (2020-02-19)
Early transcranial direct current stimulation treatment exerts neuroprotective effects on 6-OHDA-induced Parkinsonism in rats.Xiao-Jun Feng et al.Brain stimulation, 13(3), 655-663 (2020-04-15)
Thioredoxin-Interacting Protein (TXNIP) Regulates Parkin/PINK1-mediated Mitophagy in Dopaminergic Neurons Under High-glucose Conditions: Implications for Molecular Links Between Parkinson's Disease and Diabetes.Cun-Jin Su et al.Neuroscience bulletin, 36(4), 346-358 (2020-01-16)
Protein kinase C delta mediated cytotoxicity of 6-Hydroxydopamine via sustained extracellular signal-regulated kinase 1/2 activation in PC12 cells.Ying Fan et al.Neurological research, 36(1), 53-64 (2013-10-11)
Lipid Analysis of the 6-Hydroxydopamine-Treated SH-SY5Y Cell Model for Parkinson's Disease.Helena Xicoy et al.Molecular neurobiology, 57(2), 848-859 (2019-09-08)
Protective effects of DA-9805 on dopaminergic neurons against 6-hydroxydopamine-induced neurotoxicity in the models of Parkinson's disease.Hyeyoon Eo et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 117, 109184-109184 (2019-08-08)
Sympathetic nervous system controls resolution of inflammation via regulation of repulsive guidance molecule A.Andreas Körner et al.Nature communications, 10(1), 633-633 (2019-02-09)
Changes in Dendritic Spine Density and Inhibitory Perisomatic Connectivity onto Medium Spiny Neurons in L-Dopa-Induced Dyskinesia.G Gomez et al.Molecular neurobiology, 56(9), 6261-6275 (2019-02-13)
Attenuated baroreflex in a Parkinson's disease animal model coincides with impaired activation of non-C1 neurons.Laís M Cabral et al.Autonomic neuroscience : basic & clinical, 225, 102655-102655 (2020-02-25)
Activation and blockade of 5-HT6 receptor in the medial septum-diagonal band recover working memory in the hemiparkinsonian rats.Libo Li et al.Brain research, 1748, 147072-147072 (2020-08-28)
Effects of the probiotic formulation SLAB51 in in vitro and in vivo Parkinson's disease models.Vanessa Castelli et al.Aging, 12(5), 4641-4659 (2020-03-11)
Salidroside Protects Against 6-Hydroxydopamine-Induced Cytotoxicity by Attenuating ER Stress.Kai Tao et al.Neuroscience bulletin, 32(1), 61-69 (2016-01-15)
Alpha-lipoic acid protects against 6-hydroxydopamine-induced neurotoxicity in a rat model of hemi-parkinsonism.Mohammadreza Jalali-Nadoushan et al.Brain research, 1505, 68-74 (2013-02-19)
Differential Effects of LPS and 6-OHDA on Microglia's Morphology in Rats: Implications for Inflammatory Model of Parkinson's Disease.Irving Parra et al.Neurotoxicity research, 37(1), 1-11 (2019-09-04)
Fraternine, a Novel Wasp Peptide, Protects against Motor Impairments in 6-OHDA Model of Parkinsonism.Andréia Mayer Biolchi et al.Toxins, 12(9) (2020-09-02)
Chemical sympathectomy attenuates inflammation, glycocalyx shedding and coagulation disorders in rats with acute traumatic coagulopathy.Lin Xu et al.Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 26(2), 152-160 (2014-10-18)
An In Vitro Partial Lesion Model of Differentiated Human Mesencephalic Neurons: Effect of Pericyte Secretome on Phenotypic Markers.Abderahim Gaceb et al.Journal of molecular neuroscience : MN, 70(11), 1914-1925 (2020-05-31)
In the rat forced swimming test, NA-system mediated interactions may prevent the 5-HT properties of some subacute antidepressant treatments being expressedReneric JP, et al. European Neuropsychopharmacology, 12(2), 159-171 (2002)
The hTH-GFP reporter rat model for the study of Parkinson's disease.Lorraine Iacovitti et al.PloS one, 9(12), e113151-e113151 (2014-12-03)
Alternative splicing of AMPA receptor subunits in the 6-OHDA-lesioned rat model of Parkinson's disease and L-DOPA-induced dyskinesia.Christopher Kobylecki et al.Experimental neurology, 247, 476-484 (2013-01-31)
Reversal of hyperactive subthalamic circuits differentially mitigates pain hypersensitivity phenotypes in parkinsonian mice.Yiwen Luan et al.Proceedings of the National Academy of Sciences of the United States of America, 117(18), 10045-10054 (2020-04-22)
Innervating sympathetic neurons regulate heart size and the timing of cardiomyocyte cell cycle withdrawal.R E Kreipke et al.The Journal of physiology, 593(23), 5057-5073 (2015-10-01)
Astrocytes in the rat nucleus tractus solitarii are critical for cardiovascular reflex control.Li-Hsien Lin et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(47), 18608-18617 (2013-11-22)
Parkinson's disease and enhanced inflammatory response.Iva Stojkovska et al.Experimental biology and medicine (Maywood, N.J.), 240(11), 1387-1395 (2015-03-15)
Amelioration of L-Dopa-Associated Dyskinesias with Triterpenoic Acid in a Parkinsonian Rat Model.Babongile C Ndlovu et al.Neurotoxicity research, 29(1), 126-134 (2015-10-16)
Pharmacological Inhibition of HDAC6 Attenuates NLRP3 Inflammatory Response and Protects Dopaminergic Neurons in Experimental Models of Parkinson's Disease.Shaoqi Yan et al.Frontiers in aging neuroscience, 12, 78-78 (2020-04-17)
Late aging-associated increases in L-DOPA-induced dyskinesia are accompanied by heightened neuroinflammation in the hemi-parkinsonian rat.Kathryn Lanza et al.Neurobiology of aging, 81, 190-199 (2019-07-16)
MES23.5 DA Immortalized Neuroblastoma Cells Self-protect Against Early Injury by Overexpressing Glial Cell-derived Neurotrophic Factor via Akt1/Eya1/Six2 Signaling.Jin Gao et al.Journal of molecular neuroscience : MN, 70(3), 328-339 (2019-11-14)
Co-treatment with rivastigmine and idalopirdine reduces the propensity for falls in a rat model of falls in Parkinson's disease.Ajeesh Koshy Cherian et al.Psychopharmacology, 236(6), 1701-1715 (2019-01-05)
Orbitofrontal or accumbens dopamine depletion does not affect risk-based decision making in rats.Bettina Mai et al.Cognitive, affective & behavioral neuroscience, 15(3), 507-522 (2015-04-11)
Effectiveness of Fragment C Domain of Tetanus Toxin and Pramipexole in an Animal Model of Parkinson's Disease.Felipe Patricio et al.Neurotoxicity research, 35(3), 699-710 (2019-01-05)
The anatomy and metabolome of the lymphatic system in the brain in health and disease.Wenbo He et al.Brain pathology (Zurich, Switzerland), 30(2), 392-404 (2019-11-21)
Human autologous iPSC-derived dopaminergic progenitors restore motor function in Parkinson's disease models.Bin Song et al.The Journal of clinical investigation, 130(2), 904-920 (2019-11-13)
Repeated intrastriatal application of botulinum neurotoxin-A did not influence choline acetyltransferase-immunoreactive interneurons in hemiparkinsonian rat brain - A histological, stereological and correlational analysis.Alexander Hawlitschka et al.Brain research, 1742, 146877-146877 (2020-05-11)
Noradrenaline neuron degeneration contributes to motor impairments and development of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease.Eunju Shin et al.Experimental neurology, 257, 25-38 (2014-04-22)
Arachidonyl-2'-chloroethylamide (ACEA), a synthetic agonist of cannabinoid receptor, increases CB1R gene expression and reduces dyskinesias in a rat model of Parkinson's disease.Melissa Leija-Salazar et al.Pharmacology, biochemistry, and behavior, 194, 172950-172950 (2020-05-16)
ser31 Tyrosine hydroxylase phosphorylation parallels differences in dopamine recovery in nigrostriatal pathway following 6-OHDA lesion.Michael F Salvatore Journal of neurochemistry, 129(3), 548-558 (2014-01-15)
Brain-targeted intranasal delivery of dopamine with borneol and lactoferrin co-modified nanoparticles for treating Parkinson's disease.Shengnan Tang et al.Drug delivery, 26(1), 700-707 (2019-07-11)
High-throughput 16S rRNA gene sequencing reveals that 6-hydroxydopamine affects gut microbial environment.Jin Gyu Choi et al.PloS one, 14(8), e0217194-e0217194 (2019-08-14)
Striatal astrocytes engulf dopaminergic debris in Parkinson's disease: A study in an animal model.Ingrid Morales et al.PloS one, 12(10), e0185989-e0185989 (2017-10-14)
C60 fullerenes increase the intensity of rotational movements in non‑anesthetized hemiparkinsonic rats.Andriy V Maznychenko et al.Acta neurobiologiae experimentalis, 80(1), 32-37 (2020-03-28)
Local Change in Urinary Bladder Contractility Following CNS Dopamine Denervation in the 6-OHDA Rat Model of Parkinson's Disease.Reinika Mitra et al.Journal of Parkinson's disease, 5(2), 301-311 (2015-02-24)
Effects of vagus nerve stimulation are mediated in part by TrkB in a parkinson's disease model.Ariana Q Farrand et al.Behavioural brain research, 373, 112080-112080 (2019-07-14)
Cell-intrinsic adrenergic signaling controls the adaptive NK cell response to viral infection.Carlos Diaz-Salazar et al.The Journal of experimental medicine, 217(4) (2020-02-12)
Acute and Chronic Dopaminergic Depletion Differently Affect Motor Thalamic Function.Giuseppe Di Giovanni et al.International journal of molecular sciences, 21(8) (2020-04-25)
Sympathetic innervation, norepinephrine content, and norepinephrine turnover in orthotopic and spontaneous models of breast cancer.Mercedes J Szpunar et al.Brain, behavior, and immunity, 53, 223-233 (2016-01-01)
Cardiovascular alterations in rats with Parkinsonism induced by 6-OHDA and treated with Domperidone.Laís D Rodrigues et al.Scientific reports, 9(1), 8965-8965 (2019-06-22)
Stimulation of retrotrapezoid nucleus Phox2b-expressing neurons rescues breathing dysfunction in an experimental Parkinson's disease rat model.Silvio A Fernandes-Junior et al.Brain pathology (Zurich, Switzerland), 30(5), 926-944 (2020-06-05)
PET imaging of dopamine transporters with [(18)F]FE-PE2I: Effects of anti-Parkinsonian drugs.Ji-In Bang et al.Nuclear medicine and biology, 43(2), 158-164 (2016-02-14)
Anthraquinone from Edible Fungi Pleurotus ostreatus Protects Human SH-SY5Y Neuroblastoma Cells Against 6-Hydroxydopamine-Induced Cell Death-Preclinical Validation of Gene Knockout Possibilities of PARK7, PINK1, and SNCA1 Using CRISPR SpCas9.Bindhu J et al.Applied biochemistry and biotechnology, 191(2), 555-566 (2019-12-11)
Edaravone protects neurons in the rat substantia nigra against 6-hydroxydopamine-induced oxidative stress damage.Xiqi Liu et al.Cell biochemistry and biophysics, 70(2), 1247-1254 (2014-06-21)
Functional Role of the Disulfide Isomerase ERp57 in Axonal Regeneration.Valentina Castillo et al.PloS one, 10(9), e0136620-e0136620 (2015-09-12)
Disubstituted Dithiolethione ACDT Exerts Neuroprotective Effects Against 6-Hydroxydopamine-Induced Oxidative Stress in SH-SY5Y Cells.Swati Betharia et al.Neurochemical research, 44(8), 1878-1892 (2019-06-14)
Distinct anti-dyskinetic effects of amantadine and group II metabotropic glutamate receptor agonist LY354740 in a rodent model: An electrophysiological perspective.Cong Zheng et al.Neurobiology of disease, 139, 104807-104807 (2020-02-24)
RETRACTED: 6-OHDA-induced apoptosis and mitochondrial dysfunction are mediated by early modulation of intracellular signals and interaction of Nrf2 and NF-κB factors.Julio C Tobón-Velasco et al.Toxicology, 304, 109-119 (2013-01-01)
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