1-Phenylpyrazole | CAS:1126-00-7
1-Phenylpyrazole
- 名称:1-苯基吡唑 | 1-Phenylpyrazole
- CAS号:1126-00-7
- 别名:1-Phenyl-1H-pyrazole
- 分子式:C9H8N2
- 分子量:144.17
- EINESC号:214-415-1
产品描述
物理化学性质
沸点 | 141-142 ºC (30 mmHg) |
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闪点 | 109 ºC |
密度 | 1.09 |
折射率 | 1.594-1.598 |
安全数据
危险品标志 | Xi |
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危险类别码 | R36/37/38 |
安全说明书 | S26;S37/39 |
产品合成路线
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Refractory hypotension due to Rogaine® (minoxidil) ingestion managed with midodrine.Alexander Garrard et al.Clinical toxicology (Philadelphia, Pa.), 49(10), 907-909 (2011-11-15)
[Orthostatic hypotension: implications for the treatment of cardiovascular diseases].Jacques Mansourati Presse medicale (Paris, France : 1983), 41(11), 1111-1115 (2012-07-24)
A patient treated with tilt training and midodrine after 68 seconds asystole during head-up tilt table testing.Fahrettin Oz et al.Acta cardiologica, 66(4), 523-525 (2011-09-08)
Midodrine and clonidine in patients with cirrhosis and refractory or recurrent ascites: a randomized pilot study.Virendra Singh et al.The American journal of gastroenterology, 108(4), 560-567 (2013-02-20)
A double-blind placebo-controlled cross-over study of the vascular effects of midodrine in neuropathic compared with hyperadrenergic postural tachycardia syndrome.Amanda J Ross et al.Clinical science (London, England : 1979), 126(4), 289-296 (2013-08-28)
Determination of midodrine in human plasma by high-performance liquid chromatography with fluorescence detectionYoshida H, et al. Analytical Sciences, 19(2), 317-319 (2003)
Peptides in postural orthostatic tachycardia syndrome: players or epiphenomena?David G Benditt et al.Journal of the American College of Cardiology, 60(4), 321-323 (2012-07-21)
Transient ischemic attack caused by delayed orthostatic hypotension in an elderly hypertensive patient.Gianluigi Galizia et al.Geriatrics & gerontology international, 12(3), 565-567 (2012-06-21)
Effectiveness of midodrine treatment in patients with recurrent vasovagal syncope not responding to non-pharmacological treatment (STAND-trial).Jacobus J C M Romme et al.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 13(11), 1639-1647 (2011-07-15)
Are there any contraindications to using midodrine for intradialytic hypotension?Andrew A House Seminars in dialysis, 24(4), 402-403 (2011-08-02)
Probable hereditary multiple system atrophy-autonomic (MSA-A) in a family in the United States.A D Hohler et al.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 19(3), 479-480 (2012-01-18)
New insights into the management of hepato-renal syndrome.Dietrich Hasper et al.Liver international : official journal of the International Association for the Study of the Liver, 31 Suppl 3, 27-30 (2011-08-17)
Efficacy of atomoxetine versus midodrine for the treatment of orthostatic hypotension in autonomic failure.Claudia E Ramirez et al.Hypertension (Dallas, Tex. : 1979), 64(6), 1235-1240 (2014-09-04)
Ejaculatory dysfunction in spinal cord injury men is suggestive of dyssynergic ejaculation.J M Soler et al.European journal of physical and rehabilitation medicine, 47(4), 677-681 (2012-01-10)
Trials to address efficacy of midodrine 18 years after it gains FDA approval.Mike Mitka JAMA, 307(11), 1124-1124 (2012-03-23)
The role of eNOS phosphorylation in causing drug-induced vascular injury.Grainne A McMahon Tobin et al.Toxicologic pathology, 42(4), 709-724 (2014-04-08)
Orthostatic effects of midodrine versus L-NAME on cerebral blood flow and the renin-angiotensin-aldosterone system in tetraplegia.Jill M Wecht et al.Archives of physical medicine and rehabilitation, 92(11), 1789-1795 (2011-07-19)
[Therapies for postural tachycardia syndrome in children].Feng-wen Zhang et al.Zhonghua er ke za zhi = Chinese journal of pediatrics, 49(6), 428-432 (2011-09-20)
HPLC analysis of midodrine and desglymidodrine in culture medium: evaluation of static and shaken conditions on the biotransformation by fungi.Thiago Barth et al.Journal of chromatographic science, 51(5), 460-467 (2012-10-12)
[Orthostatic hypotension: what to think of it and what to do?].Bernard Waeber et al.Revue medicale suisse, 9(397), 1618-1621 (2013-10-01)
Flow-mediated vasodilation as a predictor of therapeutic response to midodrine hydrochloride in children with postural orthostatic tachycardia syndrome.Ying Liao et al.The American journal of cardiology, 112(6), 816-820 (2013-06-06)
Stability indicating RP-HPLC assay method for estimation of midodrine hydrochloride in bulk and tabletsJain.KH, et al. International Journal of Pharmacy and Pharmaceutical Sciences, 9(9), 283-287 (2016)
Midodrine hydrochloride and the treatment of orthostatic hypotension in tetraplegia: two cases and a review of the literature.D B Barber et al.Spinal cord, 38(2), 109-111 (2000-04-13)
The Orthostatic Hypotension Questionnaire (OHQ): validation of a novel symptom assessment scale.Horacio Kaufmann et al.Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 22(2), 79-90 (2011-11-03)
Postural orthostatic tachycardia syndrome with increased erythrocytic hydrogen sulfide and response to midodrine hydrochloride.Jinyan Yang et al.The Journal of pediatrics, 163(4), 1169-1173 (2013-06-04)
MicroRNA changes in rat mesentery and serum associated with drug-induced vascular injury.Roberta A Thomas et al.Toxicology and applied pharmacology, 262(3), 310-320 (2012-05-26)
Takotsubo cardiomyopathy after midodrine therapy.Vijay S Ramanath et al.Texas Heart Institute journal, 39(1), 158-159 (2012-03-14)
A prospective, 1-year follow-up study of postural tachycardia syndrome.Kurt Kimpinski et al.Mayo Clinic proceedings, 87(8), 746-752 (2012-07-17)
Hepatorenal syndrome: are we missing some prognostic factors?Marco Olivera-Martinez et al.Digestive diseases and sciences, 57(1), 210-214 (2011-08-19)
Midregional pro-adrenomedullin as a predictor for therapeutic response to midodrine hydrochloride in children with postural orthostatic tachycardia syndrome.Fengwen Zhang et al.Journal of the American College of Cardiology, 60(4), 315-320 (2012-07-21)
Rationale for the prevention of syncope trial IV: assessment of midodrine.Satish R Raj et al.Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 22(6), 275-280 (2012-05-23)
Regional neurovascular coupling and cognitive performance in those with low blood pressure secondary to high-level spinal cord injury: improved by alpha-1 agonist midodrine hydrochloride.Aaron A Phillips et al.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 34(5), 794-801 (2014-01-30)
Ion selective phosphotungestate and beta-cyclodextrin based membrane electrodes for stability-indicating determination of midodrine hydrochloride.Eman S Elzanfaly et al.Acta chimica Slovenica, 60(2), 256-262 (2013-07-25)
The combination of octreotide and midodrine is not superior to albumin in preventing recurrence of ascites after large-volume paracentesis.Khurram Bari et al.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 10(10), 1169-1175 (2012-07-18)
Midodrine: a novel therapeutic for refractory chylothorax.Douglas Z Liou et al.Chest, 144(3), 1055-1057 (2013-09-07)
Refractory hypotension after bilateral nephrectomies in a Denys-Drash patient with phenylketonuria.Amanda B Hassinger et al.Pediatric nephrology (Berlin, Germany), 28(2), 345-348 (2012-09-21)
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Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.
Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).
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