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Effect of neurotrophic factor, MDP, on rats' nerve regeneration.A A Fornazari et al.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 44(4), 327-331 (2011-02-24) Regulation of Salmonella flagellin-induced interleukin-8 in intestinal epithelial cells by muramyl dipeptide.Fu-Chen Huang Cellular immunology, 278(1-2), 1-9 (2012-11-06) The nucleotide-binding oligomerization domain-containing-2 ligand muramyl dipeptide enhances phagocytosis and intracellular killing of Escherichia coli K1 by Toll-like receptor agonists in microglial cells.Sandra Ribes et al.Journal of neuroimmunology, 252(1-2), 16-23 (2012-08-15) The crosstalk between TLR2 and NOD2 in Aspergillus fumigatus keratitis.Jiayin Wu et al.Molecular immunology, 64(2), 235-243 (2015-01-01) [Induction and protective properties of antibodies against muramyl peptides of gram-negative bacteria].M V Pashchenkov et al.Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (2)(2), 64-73 (2013-06-29) Retinal astrocytes pretreated with NOD2 and TLR2 ligands activate uveitogenic T cells.Guomin Jiang et al.PloS one, 7(7), e40510-e40510 (2012-07-19) Induction of release of tumor necrosis factor from human monocytes by staphylococci and staphylococcal peptidoglycans.Timmerman CP Infection and Immunity, 61(10), 4167-4172 (1993) Bilateral acute pyogenic conjunctivitis with iritis induced by unilateral topical application of bacterial peptidoglycan muramyl dipeptide in adult rabbits.Marlyn P Langford et al.Experimental eye research, 116, 324-336 (2013-10-19) Muramyl dipeptide responsive pathways in Crohn's disease: from NOD2 and beyond.Mohammad Salem et al.Cellular and molecular life sciences : CMLS, 70(18), 3391-3404 (2013-01-01) Claudia Loganes et al.World journal of gastroenterology, 22(44), 9734-9743 (2016-12-14)To evaluate how mucosal bacteria impact on the spontaneous and muramyl dipeptide (MDP)-induced inflammation in Crohn's disease (CD) and ulcerative colitis (UC). Colonic mucosal biopsies were collected from children with active or remissive CD, UC and controls. Two tissue samples... Enhanced anti-tumor immune responses and delay of tumor development in human epidermal growth factor receptor 2 mice immunized with an immunostimulatory peptide in poly(D,L-lactic-co-glycolic) acid nanoparticles.Diahnn F Campbell et al.Breast cancer research : BCR, 17, 48-48 (2015-04-18) Mifamurtide for high-grade, resectable, nonmetastatic osteosarcoma following surgical resection: a cost-effectiveness analysis.Sukhvinder Johal et al.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 16(8), 1123-1132 (2013-12-12) Potential of NOD receptor ligands as immunomodulators in particulate vaccine carriers.Christian Wischke et al.Journal of controlled release : official journal of the Controlled Release Society, 164(3), 299-306 (2012-07-10) Nod2 and Rip2 contribute to innate immune responses in mouse neutrophils.Yu-Jin Jeong et al.Immunology, 143(2), 269-276 (2014-04-29) Mifamurtide in metastatic and recurrent osteosarcoma: a patient access study with pharmacokinetic, pharmacodynamic, and safety assessments.P M Anderson et al.Pediatric blood & cancer, 61(2), 238-244 (2013-09-03) A new functional assay for the diagnosis of X-linked inhibitor of apoptosis (XIAP) deficiency.S Ammann et al.Clinical and experimental immunology, 176(3), 394-400 (2014-03-13) A genome-wide siRNA screen reveals positive and negative regulators of the NOD2 and NF-κB signaling pathways.Neil Warner et al.Science signaling, 6(258), rs3-rs3 (2013-01-17) New conjugates of tuftsin and muramyl dipeptide as stimulators of human monocyte-derived dendritic cells.Anna Wardowska et al.Protein and peptide letters, 20(2), 200-204 (2012-08-17) The innate immune protein Nod2 binds directly to MDP, a bacterial cell wall fragment.Catherine Leimkuhler Grimes et al.Journal of the American Chemical Society, 134(33), 13535-13537 (2012-08-04) RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition.Simone Lipinski et al.Proceedings of the National Academy of Sciences of the United States of America, 109(52), 21426-21431 (2012-12-06) Peptidoglycan and muramyl dipeptide from Staphylococcus aureus induce the expression of VEGF-A in human limbal fibroblasts with the participation of TLR2-NFκB and NOD2-EGFR.Marco Adán Juárez-Verdayes et al.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 251(1), 53-62 (2012-08-15) Muramyl dipeptide mediated activation of human bronchial epithelial cells interacting with basophils: a novel mechanism of airway inflammation.H N Qiu et al.Clinical and experimental immunology, 172(1), 81-94 (2013-03-14) FRMBP2 directs NOD2 to the membrane.Amrita Kabi et al.Proceedings of the National Academy of Sciences of the United States of America, 109(52), 21188-21189 (2012-12-19) NOD2 agonist promotes the production of inflammatory cytokines in VSMC in synergy with TLR2 and TLR4 agonists.Jinghua Sun et al.TheScientificWorldJournal, 2012, 607157-607157 (2012-09-22) Proteasomal degradation of Nod2 protein mediates tolerance to bacterial cell wall components.Kyoung-Hee Lee et al.The Journal of biological chemistry, 287(47), 39800-39811 (2012-09-29) Human umbilical cord blood mesenchymal stem cells reduce colitis in mice by activating NOD2 signaling to COX2.Hyung-Sik Kim et al.Gastroenterology, 145(6), 1392-1403 (2013-08-27) Z-100, extracted from Mycobacterium tuberculosis strain Aoyama B, promotes TNF-α production via nucleotide-binding oligomerization domain containing 2 (Nod2)-dependent NF-κB activation in RAW264.7 cells.Kokichi Katsunuma et al.Molecular immunology, 64(1), 218-227 (2014-12-17) NOD2 mutations affect muramyl dipeptide stimulation of human B lymphocytes and interact with other IBD-associated genes.Zhenwu Lin et al.Digestive diseases and sciences, 58(9), 2599-2607 (2013-05-28) Cutting edge: New chimeric NOD2/TLR2 adjuvant drastically increases vaccine immunogenicity.Vincent Pavot et al.Journal of immunology (Baltimore, Md. : 1950), 193(12), 5781-5785 (2014-11-14) Key structures of bacterial peptidoglycan and lipopolysaccharide triggering the innate immune system of higher animals: chemical synthesis and functional studies.Shoichi Kusumoto et al.Proceedings of the Japan Academy. Series B, Physical and biological sciences, 86(4), 322-337 (2010-05-01) Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition.Bram Priem et al.Cell, 183(3), 786-801 (2020-10-31) In vitro effects of sporobacterin probiotic on the function of donor granulocyte-macrophage cells.N I Gabrielyan et al.Bulletin of experimental biology and medicine, 153(5), 697-699 (2012-11-01) N-glycolylated peptidoglycan contributes to the immunogenicity but not pathogenicity of Mycobacterium tuberculosis.Jesse M Hansen et al.The Journal of infectious diseases, 209(7), 1045-1054 (2013-11-23) Respiratory syncytial virus infection augments NOD2 signaling in an IFN-β-dependent manner in human primary cells.Marloes Vissers et al.European journal of immunology, 42(10), 2727-2735 (2012-06-26) The elimination of MTC-220, a novel anti-tumor agent of conjugate of paclitaxel and muramyl dipeptide analogue, in rats.Feng You et al.Cancer chemotherapy and pharmacology, 71(6), 1453-1462 (2013-04-06) Nod2 improves barrier function of intestinal epithelial cells via enhancement of TLR responses.Ida H Hiemstra et al.Molecular immunology, 52(3-4), 264-272 (2012-07-04) Muramyl dipeptide and IL-1 effects on sleep and brain temperature after inhibition of serotonin synthesis.Imeri L The American Journal of Physiology, 273(5 Pt 2), R1663-R1668 (1997) Effect of heat-killed Escherichia coli, lipopolysaccharide, and muramyl dipeptide treatments on the immune response phenotype and allergy in neonatal pigs sensitized to the egg white protein ovomucoid.Julie Schmied et al.Clinical and vaccine immunology : CVI, 19(12), 1955-1964 (2012-10-20) Multiple antigen peptide consisting of B- and T-cell epitopes of F1 antigen of Y. pestis showed enhanced humoral and mucosal immune response in different strains of mice.Riyasat Ali et al.International immunopharmacology, 15(1), 97-105 (2012-11-24) Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes.Wei Jiang et al.The Journal of experimental medicine, 210(11), 2465-2476 (2013-09-26) Biological activity of anomeric pairs of lipophilic glycosides of N-acetylmuramyl-L-alanyl-D-isoglutamine.O V Kalyuzhin et al.Bulletin of experimental biology and medicine, 145(5), 623-625 (2009-01-16) Endosomes are specialized platforms for bacterial sensing and NOD2 signalling.Norihiro Nakamura et al.Nature, 509(7499), 240-244 (2014-04-04) Cell-mediated immune response to epitopic MAP (multiple antigen peptide) construct of LcrV antigen of Yersinia pestis in murine model.Rupesh Kumar Shreewastav et al.Cellular immunology, 278(1-2), 55-62 (2012-11-06) Intranasal vaccination with murabutide enhances humoral and mucosal immune responses to a virus-like particle vaccine.Erin M Jackson et al.PloS one, 7(7), e41529-e41529 (2012-08-03) Pivotal role of NOD2 in inflammatory processes affecting atherosclerosis and periodontal bone loss.Huaiping Yuan et al.Proceedings of the National Academy of Sciences of the United States of America, 110(52), E5059-E5068 (2013-12-11) A vitamin D3 analog augmented interleukin-8 production by human monocytic cells in response to various microbe-related synthetic ligands, especially NOD2 agonistic muramyldipeptide.Tomoko Ikeuchi et al.International immunopharmacology, 15(1), 15-22 (2012-11-20) The role of Nod1 signaling in corneal neovascularization.Sung J Kim et al.Cornea, 32(5), 674-679 (2013-01-19) NOD2-mediated innate immune signaling regulates the eicosanoids in atherosclerosis.Hui-Qing Liu et al.Arteriosclerosis, thrombosis, and vascular biology, 33(9), 2193-2201 (2013-07-23) Sensing of commensal organisms by the intracellular sensor NOD1 mediates experimental pancreatitis.Yoshihisa Tsuji et al.Immunity, 37(2), 326-338 (2012-08-21) Well-defined and potent liposomal hepatitis B vaccines adjuvanted with lipophilic MDP derivativesJain V, Vyas SP, Kohli DV. Nanomedicine (London, England), 5, 334-344 (2009) Recognition of Streptococcus pneumoniae and muramyl dipeptide by NOD2 results in potent induction of MMP-9, which can be controlled by lipopolysaccharide stimulation.Marloes Vissers et al.Infection and immunity, 82(12), 4952-4958 (2014-09-04)

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