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Palatability and pharmacokinetics of flunixin when administered to sheep through feed.Danila Marini et al.PeerJ, 4, e1800-e1800 (2016-03-19) Use of radiotelemetry to assess perinatal cardiac function in the ovine fetus and newborn.A Antolic et al.American journal of physiology. Regulatory, integrative and comparative physiology, 313(6), R660-R668 (2017-09-01) A study to assess the correlation between plasma, oral fluid and urine concentrations of flunixin meglumine with the tissue residue depletion profile in finishing-age swine.Jessica L Bates et al.BMC veterinary research, 16(1), 211-211 (2020-06-24) Doping control in horses: housing conditions and oral recycling of flunixin by ingestion of contaminated straw.M A Popot et al.Journal of veterinary pharmacology and therapeutics, 34(6), 612-614 (2011-10-15) Surgical management and long-term outcome of umbilical infection in 65 foals (2010-2015).Gil L Oreff et al.Veterinary surgery : VS, 46(7), 962-970 (2017-08-05) Plasma pharmacokinetics and milk residues of flunixin and 5-hydroxy flunixin following different routes of administration in dairy cattle.L W Kissell et al.Journal of dairy science, 95(12), 7151-7157 (2012-10-09) Assessment of post-laparotomy pain in laboratory mice by telemetric recording of heart rate and heart rate variability.Margarete Arras et al.BMC veterinary research, 3, 16-16 (2007-08-09) Dietary Amino Acid Deficiency Reduces the Utilization of Amino Acids for Growth in Growing Pigs after a Period of Poor Health.Esther Kampman-van de Hoek et al.The Journal of nutrition, 146(1), 51-58 (2015-11-27) Fate of the nonsteroidal, anti-inflammatory veterinary drug flunixin in agricultural soils and dairy manure.Inna E Popova et al.Environmental science and pollution research international, 27(16), 19746-19753 (2020-03-30) Screening and Confirmatory Analyses of Flunixin in Tissues and Bodily Fluids after Intravenous or Intramuscular Administration to Cull Dairy Cows with or without Lipopolysaccharide Challenge.Weilin L Shelver et al.Journal of agricultural and food chemistry, 64(1), 336-345 (2015-12-24) Saunders Handbook of Veterinary Drugs - E-Book (2015) Pharmacokinetics of concurrently administered intravenous lidocaine and flunixin in healthy horses.S J Waxman et al.Journal of veterinary pharmacology and therapeutics, 35(4), 413-416 (2011-12-03) Central fractalkine stimulates central prostaglandin E2 production and induces systemic inflammatory responses.Clarissa M D Mota et al.Brain research bulletin, 140, 311-317 (2018-06-06) The effect of a topical anaesthetic formulation, systemic flunixin and carprofen, singly or in combination, on cortisol and behavioural responses of Merino lambs to mulesing.D R Paull et al.Australian veterinary journal, 85(3), 98-106 (2007-03-16) Facilitative effects of environmental enrichment for cocaine relapse prevention are dependent on extinction training context and involve increased TrkB signaling in dorsal hippocampus and ventromedial prefrontal cortex.Margaret H Hastings et al.Behavioural brain research, 386, 112596-112596 (2020-03-21) Bladder Regeneration Using Multiple Acellular Scaffolds with Growth Factors in a Bladder.Luc A J Roelofs et al.Tissue engineering. Part A, 24(1-2), 11-20 (2017-03-23) Medial prefrontal serotonin in the rat is involved in goal-directed behaviour when affect guides decision making.Geoffrey van der Plasse et al.Psychopharmacology, 195(3), 435-449 (2007-09-18) Comparison of veterinary drug residue results in animal tissues by ultrahigh-performance liquid chromatography coupled to triple quadrupole or quadrupole-time-of-flight tandem mass spectrometry after different sample preparation methods, including use of a commercial lipid removal product.Anumol T, et al. Analytical and Bioanalytical Chemistry, 409(10), 2639-2653 (2017) Effects of cyclooxygenase inhibitors flunixin and deracoxib on permeability of ischaemic-injured equine jejunum.J E Tomlinson et al.Equine veterinary journal, 37(1), 75-80 (2005-01-18) Analysis of 76 veterinary pharmaceuticals from 13 classes including aminoglycosides in bovine muscle by hydrophilic interaction liquid chromatography-tandem mass spectrometry.Dasenaki ME, et al. Journal of Chromatography A, 1452, 67-80 (2016) Death of captive-bred vultures caused by flunixin poisoning in Italy.Claudia Eleni et al.Environmental toxicology and pharmacology, 68, 91-93 (2019-03-18) Maddison.EJ, et al. Small Animal Clinical Pharmacology (2008) Effects of titanium contamination caused by iron-free high-performance liquid chromatography systems on peak shape and retention of drugs with chelating properties.Mauro De Pra et al.Journal of chromatography. A, 1611, 460619-460619 (2019-11-02) Evaluation of bi-functionalized mesoporous silicas as reversed phase/cation-exchange mixed-mode sorbents for multi-residue solid phase extraction of veterinary drug residues in meat samples.Natalia Casado et al.Talanta, 165, 223-230 (2017-02-06) Evaluating a novel analgesic strategy for ring castration of ram lambs.David R Paull et al.Veterinary anaesthesia and analgesia, 39(5), 539-549 (2012-04-25) Optimized surgical techniques and postoperative care improve survival rates and permit accurate telemetric recording in exercising mice.Beat Schuler et al.BMC veterinary research, 5, 28-28 (2009-08-04) Adrenocortical function in cane toads from different environments.Sandra E Hernández et al.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 195, 65-72 (2016-02-16) Pharmacokinetics of flunixin meglumine in mature swine after intravenous, intramuscular and oral administration.Monique D Pairis-Garcia et al.BMC veterinary research, 9, 165-165 (2013-08-15) A serotonergic deficit in the dorsal periaqueductal gray matter may underpin enhanced panic-like behavior in diabetic rats.Eder Gambeta et al.Behavioural pharmacology, 28(7), 558-564 (2017-08-12) Characterization of dendritic cells subpopulations in skin and afferent lymph in the swine model.Florian Marquet et al.PloS one, 6(1), e16320-e16320 (2011-02-08) Treatment of dairy cows with PGF2α or NSAID, in combination with antibiotics, in cases of postpartum uterine inflammation.Julia Jeremejeva et al.Acta veterinaria Scandinavica, 54, 45-45 (2012-08-14) Development of a Rapid Method for the Confirmatory Analysis of Flunixin Residue in Animal Tissues Using Liquid Chromatography-Tandem Mass Spectrometry.Liu ZY, et al. Food Analytical Methods, 8(2), 352-362 (2015) [Clinical and pathological findings in an alpaca suffering from malignant catarrhal fever].D Goerigk et al.Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere, 40(2), 112-118 (2012-04-25) Detection of flunixin in equine urine using high-performance liquid chromatography with particle beam and atmospheric pressure ionization mass spectrometry after solid-phase extraction.Stanley RMS, et al. Journal of Chromatography. B, Biomedical Sciences and Applications, 667(1), 95-103 (1995) The binding of orally dosed hydrophobic active pharmaceutical ingredients to casein micelles in milk.M Cheema et al.Journal of dairy science, 100(11), 8670-8679 (2017-09-18) In-house reference materials: 5-hydroxyflunixin and meloxicam in cow milk-preparation and evaluation.Piotr Jedziniak et al.Analytica chimica acta, 637(1-2), 346-350 (2009-03-17) Screening of over 100 drugs in horse urine using automated on-line solid-phase extraction coupled to liquid chromatography-high resolution mass spectrometry for doping control.W H Kwok et al.Journal of chromatography. A, 1490, 89-101 (2017-02-22) Effects of cyclooxygenase inhibition on the gastrointestinal tract.Zaher A Radi et al.Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 58(2-3), 163-173 (2006-07-25) Drug-induced mild therapeutic hypothermia obtained by administration of a transient receptor potential vanilloid type 1 agonist.Keld Fosgerau et al.BMC cardiovascular disorders, 10, 51-51 (2010-10-12) PHARMACOKINETICS OF A SINGLE ORAL DOSE OF FLUNIXIN MEGLUMINE IN THE WHITE RHINOCEROS (CERATOTHERIUM SIMUM).Brittni East et al.Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 50(2), 322-329 (2019-07-02) Determination of acidic non-steroidal anti-inflammatory drugs in aquatic samples by liquid chromatography-triple quadrupole mass spectrometry combined with carbon nanotubes-based solid-phase extraction.I Reinholds et al.Environmental monitoring and assessment, 189(11), 568-568 (2017-10-19) Pig skin includes dendritic cell subsets transcriptomically related to human CD1a and CD14 dendritic cells presenting different migrating behaviors and T cell activation capacities.Florian Marquet et al.Journal of immunology (Baltimore, Md. : 1950), 193(12), 5883-5893 (2014-11-12) The use of electromyography interference pattern analysis to determine muscle force of the deep digital flexor muscle in healthy and laminitic horses.L C Hardeman et al.The Veterinary quarterly, 36(1), 10-15 (2015-11-27) Comparative Plasma and Interstitial Fluid Pharmacokinetics of Meloxicam, Flunixin, and Ketoprofen in Neonatal Piglets.Emma Nixon et al.Frontiers in veterinary science, 7, 82-82 (2020-03-11) COX-1 and COX-2 inhibition in horse blood by phenylbutazone, flunixin, carprofen and meloxicam: an in vitro analysis.C Beretta et al.Pharmacological research, 52(4), 302-306 (2005-06-09) Prevalence and antimicrobial susceptibility of Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni isolated from the lower respiratory tract of healthy feedlot cattle and those diagnosed with bovine respiratory disease.Edouard Timsit et al.Veterinary microbiology, 208, 118-125 (2017-09-11) Validation of a rapid lateral flow test for the simultaneous determination of β-lactam drugs and flunixin in raw milk.David Douglas et al.Journal of food protection, 75(7), 1270-1277 (2012-09-18) Effects of ischemia and the cyclooxygenase inhibitor flunixin on in vitro passage of lipopolysaccharide across equine jejunum.Julia E Tomlinson et al.American journal of veterinary research, 65(10), 1377-1383 (2004-11-05) Electrospray ionization rapid screening sans liquid chromatography column: A sensitive method for detection and quantification of chemicals in animal tissues and urine.Shubhashis Chakrabarty et al.Rapid communications in mass spectrometry : RCM, 34(20), e8876-e8876 (2020-07-07) Abcg2 transporter affects plasma, milk and tissue levels of meloxicam.Alba M Garcia-Lino et al.Biochemical pharmacology, 175, 113924-113924 (2020-03-29) Recording Electrical Brain Activity with Novel Stretchable Electrodes Based on Supersonic Cluster Beam Implantation Nanotechnology on Conformable Polymers.Vadym Gnatkovsky et al.International journal of nanomedicine, 14, 10079-10089 (2020-01-11) Effects of the cyclooxygenase inhibitor meloxicam on recovery of ischemia-injured equine jejunum.Dianne Little et al.American journal of veterinary research, 68(6), 614-624 (2007-06-05) A high-throughput and broad-spectrum screening method for analysing over 120 drugs in horse urine using liquid chromatography-high-resolution mass spectrometry.Jenny K Y Wong et al.Drug testing and analysis, 12(7), 900-917 (2020-04-09) Multiresidue method for the determination of pharmacologically active substances in egg and honey using a continuous solid-phase extraction system and gas chromatography-mass spectrometry.Abdelmonaim Azzouz et al.Food chemistry, 178, 63-69 (2015-02-24) Toxic influence. Nature, 514(7523), 404-404 (2014-10-25) Effects of non-steroidal anti-inflammatory drugs on proliferation, differentiation and migration in equine mesenchymal stem cells.Maike Müller et al.Cell biology international, 35(3), 235-248 (2010-11-20) Changes in the inspiratory pattern contribute to modulate the sympathetic activity in sino-aortic denervated rats.Mateus R Amorim et al.Experimental physiology, 102(9), 1100-1117 (2017-06-24) Identification of the first New Zealand case of equine multinodular pulmonary fibrosis.M Dunowska et al.New Zealand veterinary journal, 62(4), 226-231 (2014-03-07) Ovariectomy-induced depressive-like behavior and brain glucose metabolism changes in female rats are not affected by chronic mild stress.M A Khayum et al.Psychoneuroendocrinology, 115, 104610-104610 (2020-02-24) Ultra-performance liquid chromatography-tandem mass spectrometry determination and depletion profile of flunixin residues in tissues after single oral administration in rabbits.Ai-Ling Zhu et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 934, 8-15 (2013-07-31) Distribution of Flunixin Residues in Muscles of Dairy Cattle Dosed with Lipopolysaccharide or Saline and Treated with Flunixin by Intravenous or Intramuscular Injection.Weilin L Shelver et al.Journal of agricultural and food chemistry, 64(51), 9697-9701 (2016-12-14) Deep brain stimulation affects conditioned and unconditioned anxiety in different brain areas.A van Dijk et al.Translational psychiatry, 3, e289-e289 (2013-08-01) Pharmacokinetics of flunixin in chickens after oral and intravenous administration.J M B Musser Journal of veterinary pharmacology and therapeutics, 33(3), 312-314 (2010-06-19) Robinson EN and Sprayberry.AK Current Therapy in Equine Medicine (2009) First detection of an NSAID, flunixin, in sheep's wool using GC-MS.Ngaio Richards et al.Environmental pollution (Barking, Essex : 1987), 159(5), 1446-1450 (2011-03-02) Simultaneous determination of residues of non-steroidal anti-inflammatory drugs and glucocorticosteroids in animal muscle by liquid chromatography-tandem mass spectrometry.Jedziniak P, et al. Food Analytical Methods, 9(6), 1837-1848 (2016) The effect of breed and sex on sulfamethazine, enrofloxacin, fenbendazole and flunixin meglumine pharmacokinetic parameters in swine.J T Howard et al.Journal of veterinary pharmacology and therapeutics, 37(6), 531-541 (2014-04-16) Nicotine vapor inhalation escalates nicotine self-administration.Nicholas W Gilpin et al.Addiction biology, 19(4), 587-592 (2012-12-18) Drug contamination of the equine racetrack environment: a preliminary examination.S A Barker Journal of veterinary pharmacology and therapeutics, 31(5), 466-471 (2008-11-13) Questions dosage used in equine study.Frank K Reilly American journal of veterinary research, 67(5), 747-747 (2006-05-03) Central serotonin attenuates LPS-induced systemic inflammation.Clarissa M D Mota et al.Brain, behavior, and immunity, 66, 372-381 (2017-07-21) Wheat and barley differently affect porcine intestinal microbiota.Eva Weiss et al.Journal of the science of food and agriculture, 96(6), 2230-2239 (2015-07-16) Participation of hippocampal nitric oxide synthase and soluble guanylate cyclase in the modulation of behavioral responses elicited by the rat forced swimming test.Amanda J Sales et al.Behavioural pharmacology, 28(1), 19-29 (2016-10-26) In vivo analysis of a first-in-class tri-alkyl norspermidine-biaryl antibiotic in an active release coating to reduce the risk of implant-related infection.Dustin L Williams et al.Acta biomaterialia, 93, 36-49 (2019-02-03) Efficacy of ceftiofur and flunixin in the early treatment of bronchopneumonia in weaners.D J Halloy et al.The Veterinary record, 158(9), 291-296 (2006-03-07) A comparative study on the adverse effects of flunixin, ketoprofen and phenylbutazone in miniature donkeys: haematological, biochemical and pathological findings.A A Mozaffari et al.New Zealand veterinary journal, 58(5), 224-228 (2010-10-12) Simultaneous analysis of flunixin, naproxen, ethacrynic acid, indomethacin, phenylbutazone, mefenamic acid and thiosalicycic acid in plasma and urine by high-performance liquid chromatography and gas chromatography?mass spectrometry.Singh KA, et al. Analyst, 568(2), 351-361 (1991) Effect of day of transfer and treatment administration on the recipient on pregnancy rates after equine embryo transfer.D Panzani et al.Veterinary research communications, 33 Suppl 1, 113-116 (2009-07-14) Flunixin horse pill use in human associated with peptic ulcer disease.Matt M Blankenship et al.The Annals of pharmacotherapy, 42(3), 448-448 (2008-02-28) Online eluent-switching technique coupled anion-exchange liquid chromatography-ion trap tandem mass spectrometry for analysis of non-steroidal anti-inflammatory drugs in pig serum.Chang KC, et al. Journal of Chromatography A, 1422, 222-229 (2015) Echocardiographic assessment of myocardial infarction: comparison of a rat model in two strains.R Esmaeili et al.Iranian journal of veterinary research, 18(1), 30-35 (2017-06-08) Effects of flunixin on cardiorespiratory, plasma lactate and stride length responses to intense treadmill exercise in Standardbred trotters.P Kallings et al.Equine veterinary journal. Supplement, (38)(38), 618-623 (2011-05-27)

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