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1-Cyclohexene-1-carboxaldehyde | CAS:1192-88-7
1-Cyclohexene-1-carboxaldehyde
  • 名称:1-环己烯-1-甲醛 | 1-Cyclohexene-1-carboxaldehyde
  • CAS号:1192-88-7
  • 别名:
  • 分子式:C7H10O
  • 分子量:110.15
  • EINESC号:

产品描述

物理化学性质

沸点 61 ºC (10 mmHg)
闪点 65 ºC
密度 0.966

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来源 SDS样本
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A new high-performance liquid chromatography method determines low production of 9-beta-D-arabinofuranosylguanine triphosphate, an active metabolite of nelarabine, in adult T-cell leukemia cells.Takahiro Yamauchi et al.Oncology reports, 23(2), 499-504 (2010-01-01) Enhanced toxicity of purine nucleoside analogs in cells expressing Drosophila melanogaster nucleoside kinase mutants.N Solaroli et al.Gene therapy, 14(1), 86-92 (2006-08-04) Dual mechanisms of 9-beta-D-arabinofuranosylguanine resistance in CEM T-lymphoblast leukemia cells.S Curbo et al.Biochemical and biophysical research communications, 285(1), 40-45 (2001-07-05) Mechanisms for T-cell selective cytotoxicity of arabinosylguanine.Carlos O Rodriguez et al.Blood, 102(5), 1842-1848 (2003-05-17) Pharmacokinetics of nelarabine and 9-beta-D-arabinofuranosyl guanine in pediatric and adult patients during a phase I study of nelarabine for the treatment of refractory hematologic malignancies.D F Kisor et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 18(5), 995-1003 (2000-03-01) Acute cytotoxicity of arabinofuranosyl nucleoside analogs is not dependent on mitochondrial DNA.Sophie Curbo et al.Experimental cell research, 315(15), 2539-2543 (2009-06-02) Novel selective human mitochondrial kinase inhibitors: design, synthesis and enzymatic activity.Nunzia Ciliberti et al.Bioorganic & medicinal chemistry, 15(8), 3065-3081 (2007-02-28) Induction of fetal hemoglobin and ABCB1 gene expression in 9-β-D-arabinofuranosylguanine-resistant MOLT-4 cells.Anna Fyrberg et al.Cancer chemotherapy and pharmacology, 68(3), 583-591 (2010-11-27) Reduced levels of mitochondrial DNA increases the toxicity of 9-beta-D-arabinofuranosylguanine (araG).M Bjerke et al.Nucleosides, nucleotides & nucleic acids, 27(6), 746-749 (2008-07-05) Effects of 9-beta-D-arabinofuranosylguanine on mitochondria in CEM T-lymphoblast leukemia cells.Sophie Curbo et al.Biochemical and biophysical research communications, 307(4), 942-947 (2003-07-25) In vitro efficacy of forodesine and nelarabine (ara-G) in pediatric leukemia.Irene Homminga et al.Blood, 118(8), 2184-2190 (2011-07-07) Synthesis of 2'-deoxy-2'-[18F]fluoro-9-β-D-arabinofuranosylguanine: a novel agent for imaging T-cell activation with PET.Mohammad Namavari et al.Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 13(5), 812-818 (2010-09-15) The novel nucleoside transport system exhibited by NB4 cells, csg, transports deoxyguanosine analogues, including ara-G.Sheryl A Flanagan et al.Biochemical pharmacology, 66(5), 733-737 (2003-09-02) Nucleoside analogues: mechanisms of drug resistance and reversal strategies.C M Galmarini et al.Leukemia, 15(6), 875-890 (2001-06-22) A potential role of fetal hemoglobin in the development of multidrug resistance.A Fyrberg et al.Biochemical and biophysical research communications, 427(3), 456-460 (2012-08-23) In vitro chemo-sensitivity of B-chronic lymphocytic leukaemia to ara-G.T Bromidge et al.Leukemia research, 24(7), 623-626 (2000-06-27) Combination of guanine arabinoside and Bcl-2 inhibitor YC137 overcomes the cytarabine resistance in HL-60 leukemia cell line.Rie Nishi et al.Cancer science, 104(4), 502-507 (2013-01-17) Arabinosylguanine is phosphorylated by both cytoplasmic deoxycytidine kinase and mitochondrial deoxyguanosine kinase.Carlos O Rodriguez et al.Cancer research, 62(11), 3100-3105 (2002-05-31) Synthesis of 9-beta-d-arabinofuranosylguanine by combined use of two whole cell biocatalysts.Rosario Médici et al.Bioorganic & medicinal chemistry letters, 19(15), 4210-4212 (2009-06-16) Resistance to mitochondrial- and Fas-mediated apoptosis in human leukemic cells with acquired resistance to 9-beta-D-arabinofuranosylguanosine.Emma Månsson et al.Biochemical and biophysical research communications, 298(3), 338-344 (2002-11-05) Low level of mitochondrial deoxyguanosine kinase is the dominant factor in acquired resistance to 9-beta-D-arabinofuranosylguanine cytotoxicity.Kourosh Lotfi et al.Biochemical and biophysical research communications, 293(5), 1489-1496 (2002-06-11) Plasma and cerebrospinal fluid pharmacokinetics of nelarabine in nonhuman primates.Stacey L Berg et al.Cancer chemotherapy and pharmacology, 59(6), 743-747 (2006-09-06) Nelarabine: a new purine analog in the treatment of hematologic malignancies.Sophie Curbo et al.Reviews on recent clinical trials, 1(3), 185-192 (2008-05-14) Differential incorporation of 1-beta-D-arabinofuranosylcytosine and 9-beta-D-arabinofuranosylguanine into nuclear and mitochondrial DNA.C Zhu et al.FEBS letters, 474(2-3), 129-132 (2000-06-06) Activation of guanine-β-D-arabinofuranoside and deoxyguanosine to triphosphates by a common pathway blocks T lymphoblasts at different checkpoints.Luigi Leanza et al.Experimental cell research, 316(20), 3443-3453 (2010-07-07)
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