4-Amino-1-methylpiperidine dihydrochloride | CAS:1193-03-9
4-Amino-1-methylpiperidine dihydrochloride
- 名称:4-氨基-1-甲基哌啶二盐酸盐 | 4-Amino-1-methylpiperidine dihydrochloride
- CAS号:1193-03-9
- 别名:
- 分子式:C6H14N2.2(HCl)
- 分子量:187.11
- EINESC号:
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物理化学性质
熔点 | 247 ºC* |
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Blood pressure reduction does not reduce perihematoma oxygenation: a CT perfusion study.Mahesh P Kate et al.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 34(1), 81-86 (2013-09-21)
Neuroprotective role of hydralazine in rat spinal cord injury-attenuation of acrolein-mediated damage.Jonghyuck Park et al.Journal of neurochemistry, 129(2), 339-349 (2013-11-30)
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Hydralazine-induced lupus erythematosus: what is the mechanism?Ji Young Oh et al.Journal of clinical hypertension (Greenwich, Conn.), 14(12), 887-887 (2012-12-05)
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Biomimetic microfluidic device for in vitro antihypertensive drug evaluation.Lei Li et al.Molecular pharmaceutics, 11(7), 2009-2015 (2014-03-29)
Hydralazine and hydralazine hydrochloride. IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 24, 85-100 (1980-01-01)
Regulation of vascular tone and pulse wave velocity in human muscular conduit arteries: selective effects of nitric oxide donors to dilate muscular arteries relative to resistance vessels.Henry Fok et al.Hypertension (Dallas, Tex. : 1979), 60(5), 1220-1225 (2012-10-10)
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Isosorbide dinitrate and hydralazine hydrochloride: a review of efficacy and safety.Keith C Ferdinand Expert review of cardiovascular therapy, 3(6), 993-1001 (2005-11-19)
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Coated hydralazine hydrochloride beads for sustained release after oral administration.M Akhlaq Mughal et al.Drug development and industrial pharmacy, 39(9), 1439-1446 (2012-10-13)
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Genetic mechanisms possibly leading to racially different responses to nitrate therapy.Gustavo H Oliveira-Paula The American journal of cardiology, 114(7), 1126-1126 (2014-09-13)
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