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N-(Tetrahydro-2-oxo-3-thienyl)-acetamide | CAS:1195-16-0
N-(Tetrahydro-2-oxo-3-thienyl)-acetamide
  • 名称:N-(四氢-2-氧代-3-噻吩)-乙酰胺 | N-(Tetrahydro-2-oxo-3-thienyl)-acetamide
  • CAS号:1195-16-0
  • 别名:2-Acetamido-4-mercaptobutyric acid gamma-thiolactone
  • 分子式:C6H9NO2S
  • 分子量:159.20
  • EINESC号:214-793-8

产品描述

物理化学性质

熔点 109-111 ºC

安全数据

安全说明书 S22;S24/25

SDS

来源 SDS样本
Alfa-Aesar 浏览或下载
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The influence of chronic eicosanoid biosynthesis inhibition on life history of the greater waxmoth, Galleria mellonella and its ectoparasitoid, Bracon hebetor.Ender Büyükgüzel et al.Journal of insect physiology, 57(4), 501-507 (2011-02-10) Esculetin attenuates alterations in Ang II and acetylcholine mediated vascular reactivity associated with hyperinsulinemia and hyperglycemia.Almesh Kadakol et al.Biochemical and biophysical research communications, 461(2), 342-347 (2015-04-19) Cardiovascular and vasoconstrictive actions of skate bradykinin in the little skate, Leucoraja erinacea (Elasmobranchii).Patricia J Dasiewicz et al.General and comparative endocrinology, 174(2), 89-96 (2011-09-07) Aesculetin-induced apoptosis through a ROS-mediated mitochondrial dysfunction pathway in human cervical cancer cells.Jin Yang et al.Journal of Asian natural products research, 12(3), 185-193 (2010-04-15) Expanding the ChemGPS chemical space with natural products.Josefin Larsson et al.Journal of natural products, 68(7), 985-991 (2005-07-26) Investigations of FT-IR, FT-Raman, FT-NMR spectra and quantum chemical computations of Esculetin molecule.Yusuf Erdogdu Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 106, 25-33 (2013-01-29) p38 MAPK activation is required for esculetin-induced inhibition of vascular smooth muscle cells proliferation.Eun-Sun Yun et al.Toxicology in vitro : an international journal published in association with BIBRA, 25(7), 1335-1342 (2011-05-24) In vitro assessment of mutagenic and genotoxic effects of coumarin derivatives 6,7-dihydroxycoumarin and 4-methylesculetin.Edson Luis Maistro et al.Journal of toxicology and environmental health. Part A, 78(2), 109-118 (2014-11-27) A dual chromophore sensor for the detection of amines, diols, hydroxy acids, and amino alcohols.Mariia Pushina et al.Chemical communications (Cambridge, England), 55(31), 4495-4498 (2019-03-29) The hepatoprotective effect of coumarin and coumarin derivates on carbon tetrachloride-induced hepatic injury by antioxidative activities in rats.Mukadder Atmaca et al.Journal of physiology and biochemistry, 67(4), 569-576 (2011-06-10) Esculetin inhibits cell proliferation through the Ras/ERK1/2 pathway in human colon cancer cells.Sung-Suk Park et al.Oncology reports, 25(1), 223-230 (2010-11-27) Anti-obesity activity, acute toxicity, and chemical constituents of aqueous and ethanol Viola mandshurica extracts.Yoon-Young Sung et al.BMC complementary and alternative medicine, 17(1), 297-297 (2017-06-08) Intestinal anti-inflammatory activity of esculetin and 4-methylesculetin in the trinitrobenzenesulphonic acid model of rat colitis.Aline Witaicenis et al.Chemico-biological interactions, 186(2), 211-218 (2010-04-13) Esculetin induces death of human colon cancer cells via the reactive oxygen species-mediated mitochondrial apoptosis pathway.Areum Daseul Kim et al.Environmental toxicology and pharmacology, 39(2), 982-989 (2015-03-31) Canditate metabolites for ash dieback tolerance in Fraxinus excelsior.Miguel Nemesio-Gorriz et al.Journal of experimental botany, 71(19), 6074-6083 (2020-07-01) Relationship between quantum-chemical descriptors of proton dissociation and experimental acidity constants of various hydroxylated coumarins. Identification of the biologically active species for xanthine oxidase inhibition.Anna Maria Ferrari et al.European journal of medicinal chemistry, 42(7), 1028-1031 (2007-02-24) The in vivo effect of esculetin ointment and esculetin-mixed Zyderm for Zyderm.Hisayo Yamaoka et al.Plastic and reconstructive surgery, 134(1), 50e-58e (2014-07-17) [Isolation and purification of esculetin from the seeds of Euphorbia lathyris L. using high-speed counter-current chromatography].Xi Yu et al.Se pu = Chinese journal of chromatography, 28(8), 809-812 (2011-01-26) Inhibitory effect of esculetin on migration, invasion and matrix metalloproteinase-9 expression in TNF-α-induced vascular smooth muscle cells.Se-Jung Lee et al.Molecular medicine reports, 4(2), 337-341 (2011-04-07) A natural coumarin derivative esculetin offers neuroprotection on cerebral ischemia/reperfusion injury in mice.Chen Wang et al.Journal of neurochemistry, 121(6), 1007-1013 (2012-03-31) Esculetin induced changes in Mmp13 and Bmp6 gene expression and histone H3 modifications attenuate development of glomerulosclerosis in diabetic rats.Vivek Madhukar Surse et al.Journal of molecular endocrinology, 46(3), 245-254 (2011-04-01) Ectopic expression of a stress-inducible glycosyltransferase from saffron enhances salt and oxidative stress tolerance in Arabidopsis while alters anchor root formation.Oussama Ahrazem et al.Plant science : an international journal of experimental plant biology, 234, 60-73 (2015-03-26) Esculetin induces apoptosis in human colon cancer cells by inducing endoplasmic reticulum stress.Areum Daseul Kim et al.Cell biochemistry and function, 33(7), 487-494 (2015-10-07) A TD-DFT study on the hydrogen bonding of three esculetin complexes in electronically excited states: strengthening and weakening.Yu-Fang Liu et al.Journal of computational chemistry, 32(16), 3475-3484 (2011-09-16) Role of GTP-CHI links PAH and TH in melanin synthesis in silkworm, Bombyx mori.Ping Chen et al.Gene, 567(2), 138-145 (2015-05-11) The influence of chronic eicosanoid biosynthesis inhibition on life history of the greater waxmoth, Galleria mellonella and its ectoparasitoid, Bracon hebetor.Ender Büyükgüzel et al.Journal of insect physiology, 57(4), 501-507 (2011-02-10) Esculetin-induced protection of human hepatoma HepG2 cells against hydrogen peroxide is associated with the Nrf2-dependent induction of the NAD(P)H: Quinone oxidoreductase 1 gene.Sudhakar R Subramaniam et al.Toxicology and applied pharmacology, 250(2), 130-136 (2010-10-12) 7-O-methylkaempferol and -quercetin glycosides from the whole plant of Nervilia fordii.Li-Wen Tian et al.Journal of natural products, 72(6), 1057-1060 (2009-05-09) Evaluation of percutaneous absorption of esculetin: effect of chemical enhancers.Sergio del Rio Sancho et al.Planta medica, 79(2), 131-136 (2012-12-20) 6,7-Dihydroxy-4-phenylcoumarin as inhibitor of aldose reductase 2.Atsushi Kato et al.Bioorganic & medicinal chemistry letters, 20(19), 5630-5633 (2010-09-02) p38 MAPK activation is required for esculetin-induced inhibition of vascular smooth muscle cells proliferation.Eun-Sun Yun et al.Toxicology in vitro : an international journal published in association with BIBRA, 25(7), 1335-1342 (2011-05-24) In vitro assessment of mutagenic and genotoxic effects of coumarin derivatives 6,7-dihydroxycoumarin and 4-methylesculetin.Edson Luis Maistro et al.Journal of toxicology and environmental health. Part A, 78(2), 109-118 (2014-11-27) A dual chromophore sensor for the detection of amines, diols, hydroxy acids, and amino alcohols.Mariia Pushina et al.Chemical communications (Cambridge, England), 55(31), 4495-4498 (2019-03-29) The hepatoprotective effect of coumarin and coumarin derivates on carbon tetrachloride-induced hepatic injury by antioxidative activities in rats.Mukadder Atmaca et al.Journal of physiology and biochemistry, 67(4), 569-576 (2011-06-10) Esculetin inhibits cell proliferation through the Ras/ERK1/2 pathway in human colon cancer cells.Sung-Suk Park et al.Oncology reports, 25(1), 223-230 (2010-11-27) Anti-obesity activity, acute toxicity, and chemical constituents of aqueous and ethanol Viola mandshurica extracts.Yoon-Young Sung et al.BMC complementary and alternative medicine, 17(1), 297-297 (2017-06-08) Intestinal anti-inflammatory activity of esculetin and 4-methylesculetin in the trinitrobenzenesulphonic acid model of rat colitis.Aline Witaicenis et al.Chemico-biological interactions, 186(2), 211-218 (2010-04-13) Differential effects of esculetin and daphnetin on in vitro cell proliferation and in vivo estrogenicity.Fausto Alejandro Jiménez-Orozco et al.European journal of pharmacology, 668(1-2), 35-41 (2011-07-12) Canditate metabolites for ash dieback tolerance in Fraxinus excelsior.Miguel Nemesio-Gorriz et al.Journal of experimental botany, 71(19), 6074-6083 (2020-07-01) Relationship between quantum-chemical descriptors of proton dissociation and experimental acidity constants of various hydroxylated coumarins. Identification of the biologically active species for xanthine oxidase inhibition.Anna Maria Ferrari et al.European journal of medicinal chemistry, 42(7), 1028-1031 (2007-02-24) The in vivo effect of esculetin ointment and esculetin-mixed Zyderm for Zyderm.Hisayo Yamaoka et al.Plastic and reconstructive surgery, 134(1), 50e-58e (2014-07-17) [Isolation and purification of esculetin from the seeds of Euphorbia lathyris L. using high-speed counter-current chromatography].Xi Yu et al.Se pu = Chinese journal of chromatography, 28(8), 809-812 (2011-01-26) Inhibitory effect of esculetin on migration, invasion and matrix metalloproteinase-9 expression in TNF-α-induced vascular smooth muscle cells.Se-Jung Lee et al.Molecular medicine reports, 4(2), 337-341 (2011-04-07) A natural coumarin derivative esculetin offers neuroprotection on cerebral ischemia/reperfusion injury in mice.Chen Wang et al.Journal of neurochemistry, 121(6), 1007-1013 (2012-03-31) Esculetin induced changes in Mmp13 and Bmp6 gene expression and histone H3 modifications attenuate development of glomerulosclerosis in diabetic rats.Vivek Madhukar Surse et al.Journal of molecular endocrinology, 46(3), 245-254 (2011-04-01) Ectopic expression of a stress-inducible glycosyltransferase from saffron enhances salt and oxidative stress tolerance in Arabidopsis while alters anchor root formation.Oussama Ahrazem et al.Plant science : an international journal of experimental plant biology, 234, 60-73 (2015-03-26) Esculetin induces apoptosis in human colon cancer cells by inducing endoplasmic reticulum stress.Areum Daseul Kim et al.Cell biochemistry and function, 33(7), 487-494 (2015-10-07) A TD-DFT study on the hydrogen bonding of three esculetin complexes in electronically excited states: strengthening and weakening.Yu-Fang Liu et al.Journal of computational chemistry, 32(16), 3475-3484 (2011-09-16) Role of GTP-CHI links PAH and TH in melanin synthesis in silkworm, Bombyx mori.Ping Chen et al.Gene, 567(2), 138-145 (2015-05-11)
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