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2'-Hydroxyacetophenone oxime | CAS:1196-29-8
2'-Hydroxyacetophenone oxime
  • 名称:2'-羟基苯乙酮肟 | 2'-Hydroxyacetophenone oxime
  • CAS号:1196-29-8
  • 别名:Methyl 2-hydroxyphenyl ketoxime; o-Hydroxyacetophenone oxime
  • 分子式:C8H9NO2
  • 分子量:151.16
  • EINESC号:214-810-9

产品描述

物理化学性质

熔点 209-210 ºC**
密度 1.15±0.1 g/cm3 (20 ºC

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Synthesis, evaluation and docking studies on 3-alkoxy-4-methanesulfonamido acetophenone derivatives as non ulcerogenic anti-inflammatory agents.Alka Bali et al.European journal of medicinal chemistry, 49, 397-405 (2012-02-10) Novel indoline-based acyl-CoA: cholesterol acyltransferase inhibitor: Effects of introducing a methanesulfonamide group on physicochemical properties and biological activities.Yoshimichi Shoji et al.Bioorganic & medicinal chemistry, 17(16), 6020-6031 (2009-07-18) In vitro antitumor mechanism of (E)-N-(2-methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-3-yl)methanesulfonamide.Tiangong Lu et al.Molecular pharmacology, 87(1), 18-30 (2014-10-16) 2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors.Allegretti M, et al. 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C, Journal of biosciences, 64(3-4), 179-185 (2009-06-17) Conformational analysis, vibrational and NMR spectroscopic study of the methanesulfonamide-N,N'-1,2-ethanediylbis.Hamit Alyar et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 91, 39-47 (2012-02-22) Methanesulfonamide. eEROS (Encyclopedia of Reagents for Organic Synthesis) (2007) A new strategy for the synthesis of benzylic sulfonamides: palladium-catalyzed arylation and sulfonamide metathesis.Jonathan B Grimm et al.The Journal of organic chemistry, 72(21), 8135-8138 (2007-09-21) Acetic acid-derived prostaglandin-dependent colonic adaptive cytoprotection is preserved in chronic colitis: role of cyclo-oxygenase.Kei Ohara et al.International journal of colorectal disease, 18(3), 260-266 (2003-04-04) Synthesis and pharmacological evaluation of N,N-di-n-propyldopamine congeners containing phenolic bioisosteres.R D Clark et al.Journal of pharmaceutical sciences, 76(5), 411-415 (1987-05-01) A new class of carbonic anhydrase inhibitor.T H Maren et al.The Journal of biological chemistry, 268(35), 26233-26239 (1993-12-15) Synthesis, antiviral and anticancer activity of some novel thioureas derived from N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide.Sevgi Karakuş et al.European journal of medicinal chemistry, 44(9), 3591-3595 (2009-03-28) Discovery of a highly active ligand of human pregnane x receptor: a case study from pharmacophore modeling and virtual screening to "in vivo" biological activity.Géraldine Lemaire et al.Molecular pharmacology, 72(3), 572-581 (2007-06-19) Mild Pd-catalyzed N-arylation of methanesulfonamide and related nucleophiles: avoiding potentially genotoxic reagents and byproducts.Brandon R Rosen et al.Organic letters, 13(10), 2564-2567 (2011-04-23) Methanesulfonamide group at position-4 of the C-5-phenyl ring of 1,5-diarylpyrazole affords a potent class of cyclooxygenase-2 (COX-2) inhibitors.Sunil Kumar Singh et al.Bioorganic & medicinal chemistry letters, 14(7), 1683-1688 (2004-03-18) Inhibition of cyclooxygenase-2 causes a decrease in coronary flow in diabetic mice. The possible role of PGE2 and dysfunctional vasodilation mediated by prostacyclin receptor.Tomasz Przygodzki et al.Journal of physiology and biochemistry, 71(3), 351-358 (2015-05-06) Metabolism of the prostaglandin fertility regulator sulprostone in monkeys.F C Falkner Prostaglandins, 24(3), 341-350 (1982-09-01) Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner.Torsten Lowin et al.Arthritis research & therapy, 17, 321-321 (2015-11-17) A Convenient Synthesis of Chloronitrobenzonitrile Isomers and Homologs.Grivsky E M Bull. Soc. Chim. Belg., 80(3?4), 245-252 (1971) An experimental and theoretical study of dipole moments of N-[4-(9-acridinylamino)-3-methoxyphenyl]methanesulfonamide.Katarzyna Nowak et al.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 70(4), 805-810 (2007-11-23) Total synthesis of a marine alkaloid--rigidin E.Banpeng Cao et al.Marine drugs, 10(6), 1412-1421 (2012-07-24) Development and validation of an LC-MS/MS method for determination of methanesulfonamide in human urine.Roberto Anacardio et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(22), 2087-2092 (2009-06-23) Differential recovery of action potential duration and HERG currents from the effects of two methanesulfonamide class III antiarrhythmic agents, KCB-328 and dofetilide.Kiho Lee et al.Journal of cardiovascular pharmacology, 42(5), 648-655 (2003-10-25) Development and preliminary optimization of indole-N-acetamide inhibitors of hepatitis C virus NS5B polymerase.Harper S, et al. 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