密度	1.404±0.06 g/cm3 (20 º

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Cucurbitacin E as inducer of cell death and apoptosis in human oral squamous cell carcinoma cell line SAS.Chao-Ming Hung et al.International journal of molecular sciences, 14(8), 17147-17156 (2013-08-24) Effect of cucurbitacins on bilirubin-albumin binding in human plasma.H Greige-Gerges et al.Life sciences, 80(6), 579-585 (2006-11-14) Remodeling of the Actin/Spectrin Membrane-associated Periodic Skeleton, Growth Cone Collapse and F-Actin Decrease during Axonal DegenerationUnsain N, et al. Scientific Reports, 8(1), 3007-3007 (2018) Immunomodulatory activity of cucurbitacin E isolated from Ecballium elaterium.E Attard et al.Fitoterapia, 76(5), 439-441 (2005-05-24) Quantitative determination of cucurbitacin E and cucurbitacin I in homoeopathic mother tincture of Gratiola officinalis L. by HPLC.G I Kaya et al.Die Pharmazie, 63(12), 851-853 (2009-01-31) Hierarchical extraction and simultaneous determination of flavones and triterpenes in different parts of Trichosanthes kirilowii Maxim. by ultra-high-performance liquid chromatography coupled with tandem mass spectrometry.Huang-Qin Zhang et al.Journal of pharmaceutical and biomedical analysis, 167, 114-122 (2019-02-15) The induction of G2/M cell-cycle arrest and apoptosis by cucurbitacin E is associated with increased phosphorylation of eIF2alpha in leukemia cells.Yanchun Li et al.Anti-cancer drugs, 21(4), 389-400 (2010-01-30) In vivo topology converts competition for cell-matrix adhesion into directional migration.Fernanda Bajanca et al.Nature communications, 10(1), 1518-1518 (2019-04-05) Interaction of cucurbitacins with human serum albumin: Thermodynamic characteristics and influence on the binding of site specific ligands.Rony Abou-Khalil et al.Journal of photochemistry and photobiology. B, Biology, 95(3), 189-195 (2009-04-22) Anti-inflammatory activities of cucurbitacin E isolated from Citrullus lanatus var. citroides: role of reactive nitrogen species and cyclooxygenase enzyme inhibition.Siddig Ibrahim Abdelwahab et al.Fitoterapia, 82(8), 1190-1197 (2011-08-30) Cucurbitacin E inhibits breast tumor metastasis by suppressing cell migration and invasion.Tao Zhang et al.Breast cancer research and treatment, 135(2), 445-458 (2012-07-31) Growth inhibitory effect of Cucurbitacin E on breast cancer cells.Tian Lan et al.International journal of clinical and experimental pathology, 6(9), 1799-1805 (2013-09-17) In vitro and in vivo study of cucurbitacins-type triterpene glucoside from Citrullus colocynthis growing in Saudi Arabia against hepatocellular carcinoma.Seif-Eldin N Ayyad et al.Environmental toxicology and pharmacology, 33(2), 245-251 (2012-01-17) Morierinin: a new cytotoxic cucurbitacin from the leaves of Morierina montana Vieill.Marc Litaudon et al.Natural product research, 17(4), 229-233 (2003-06-26) Cucurbitacin E induces apoptosis of human prostate cancer cells via cofilin-1 and mTORC1.Xiaolong He et al.Oncology letters, 13(6), 4905-4910 (2017-06-11) Stability of cucurbitacin E in human plasma: chemical hydrolysis and role of plasma esterases.Myriam Saade et al.Biopharmaceutics & drug disposition, 30(7), 389-397 (2009-08-19) Gliotoxin Induces Cofilin Phosphorylation to Promote Actin Cytoskeleton Dynamics and Internalization of Aspergillus fumigatus Into Type II Human Pneumocyte Cells.Changjian Zhang et al.Frontiers in microbiology, 10, 1345-1345 (2019-07-06) Preparation and characterization of liposomes incorporating cucurbitacin E, a natural cytotoxic triterpene.Lamice Habib et al.International journal of pharmaceutics, 448(1), 313-319 (2013-03-26) Three-dimensional structural analysis reveals a Cdk5-mediated kinase cascade regulating hepatic biliary network branching in zebrafishDimri M, et al. Development, 144(14), 2595-2605 (2017) Cucurbitacin glucosides: antioxidant and free-radical scavenging activities.Tehila Tannin-Spitz et al.Biochemical and biophysical research communications, 364(1), 181-186 (2007-10-19) Screening of biochemical modulator by tumor cell permeability of doxorubicin.Yasuyuki Sadzuka et al.International journal of pharmaceutics, 354(1-2), 63-69 (2007-12-07) Three-dimensional structural analysis reveals a Cdk5-mediated kinase cascade regulating hepatic biliary network branching in zebrafish.Manali Dimri et al.Development (Cambridge, England), 144(14), 2595-2605 (2017-07-20) [Determination of the cucurbitacins from Cucubita pepo cv dayangua by HPLC].Xue-song Feng et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 30(4), 418-420 (2007-08-07) [Inhibitory effect of cucurbitacin E on the proliferation of ovarian cancer cells and its mechanism].Xiao-Lei Shan et al.Chinese journal of cancer, 29(1), 20-24 (2009-12-30) Cucurbitacins: elucidation of their interactions with the cytoskeleton.Xiaojuan Wang et al.PeerJ, 5, e3357-e3357 (2017-06-07) Cytotoxic and anti-HIV principles from the rhizomes of Begonia nantoensis.Pei-Lin Wu et al.Chemical & pharmaceutical bulletin, 52(3), 345-349 (2004-03-03) Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway.Yanmin Dong et al.Carcinogenesis, 31(12), 2097-2104 (2010-08-25) Cucurbitacins from the Leaves of Citrullus colocynthis (L.) Schrad.Rachid Chawech et al.Molecules (Basel, Switzerland), 20(10), 18001-18015 (2015-10-06) Stabilization of cucurbitacin E-glycoside, a feeding stimulant for diabroticite beetles, extracted from bitter Hawkesbury watermelon.Phyllis A W Martin et al.Journal of insect science (Online), 2, 19-19 (2004-09-30) Cucurbitacin E exhibits anti-inflammatory effect in RAW 264.7 cells via suppression of NF-κB nuclear translocation.Jing Qiao et al.Inflammation research : official journal of the European Histamine Research Society ... [et al.], 62(5), 461-469 (2013-01-31) Enhancement of doxorubicin concentration in the M5076 ovarian sarcoma cells by cucurbitacin E co-treatment.Yasuyuki Sadzuka et al.International journal of pharmaceutics, 383(1-2), 186-191 (2009-09-08) Cucurbitacin E inhibits the Yes‑associated protein signaling pathway and suppresses brain metastasis of human non‑small cell lung cancer in a murine model.Ping-Chih Hsu et al.Oncology reports, 42(2), 697-707 (2019-06-25)

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