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2-Amino-5-bromophenyl-2-pyridylmethanone | CAS:1563-56-0
2-Amino-5-bromophenyl-2-pyridylmethanone
  • 名称:2-氨基-5-溴苯基-2-吡啶基甲酮 | 2-Amino-5-bromophenyl-2-pyridylmethanone
  • CAS号:1563-56-0
  • 别名:2-Amino-5-bromophenyl 2-pyridylmethanone; 2-(2-Amino-5-bromobenzoyl)pyridine; 2-(5-Bromo-2-aminobenzoyl)pyridine; 2-Amino-5-bromophenyl 2-pyridyl ketone
  • 分子式:C12H9BrN2O
  • 分子量:277.12
  • EINESC号:216-352-5

产品描述

物理化学性质

熔点 98-100 ºC
沸点 451 ºC
闪点 227 ºC
密度 1.546

安全数据

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SDS

来源 SDS样本
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Milk protein isolate (MPI) as a source of dipeptidyl peptidase IV (DPP-IV) inhibitory peptides.Alice B Nongonierma et al.Food chemistry, 231, 202-211 (2017-04-30) Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes.Anand Sitaram et al.Molecular biology of the cell, 23(16), 3178-3192 (2012-06-22) The gamma/sigma1 and alpha/sigma2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site.Balraj Doray et al.Molecular biology of the cell, 18(5), 1887-1896 (2007-03-16) Aggregatibacter actinomycetemcomitans leukotoxin induces cytosol acidification in LFA-1 expressing immune cells.N Balashova et al.Molecular oral microbiology, 31(1), 106-114 (2015-09-12) Cleavage of L-leucine-containing dipeptides by Clostridium butyricum.N Khelifa et al.Bioorganic & medicinal chemistry letters, 9(1), 109-112 (1999-02-17) Ultra-high-pressure processing improves proteolysis and release of bioactive peptides with activation activities on alcohol metabolic enzymes in vitro from mushroom foot protein.Rui-Jie Zhao et al.Food chemistry, 231, 25-32 (2017-04-30) Notch signaling from the endosome requires a conserved dileucine motif.Li Zheng et al.Molecular biology of the cell, 24(3), 297-307 (2012-11-23) Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients.Gunter P Eckert et al.Neurobiology of disease, 35(2), 251-257 (2009-05-26) Observation of a sterically unfavorable side-chain conformation in a leucyl residue: crystal and molecular structure of L-leucyl-L-leucine.DMSO solvate.S N Mitra et al.Biopolymers, 34(9), 1139-1143 (1994-09-01) Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptor.Y Zhu et al.Science (New York, N.Y.), 292(5522), 1716-1718 (2001-06-02) ThPTR2, a di/tri-peptide transporter gene from Trichoderma harzianum.J A Vizcaíno et al.Fungal genetics and biology : FG & B, 43(4), 234-246 (2006-02-10) Simple estimation of absolute free energies for biomolecules.F Marty Ytreberg et al.The Journal of chemical physics, 124(10), 104105-104105 (2006-03-18) Two di-leucine-based motifs account for the different subcellular localizations of the human endothelin-converting enzyme (ECE-1) isoforms.O Valdenaire et al.Journal of cell science, 112 Pt 18, 3115-3125 (1999-08-27) A novel compound, NK150460, exhibits selective antitumor activity against breast cancer cell lines through activation of aryl hydrocarbon receptor.Kazuteru Fukasawa et al.Molecular cancer therapeutics, 14(2), 343-354 (2014-12-20) Stimulus frequency and intensity: critical determinants of opioid enhancement or inhibition of evoked methionine-enkephalin release.E Sublette et al.Brain research, 599(1), 165-170 (1992-12-18) A prospective study of serum metabolites and colorectal cancer risk.Amanda J Cross et al.Cancer, 120(19), 3049-3057 (2014-06-05) ThPTR2, a di/tri-peptide transporter gene from Trichoderma harzianum.J A Vizcaíno et al.Fungal genetics and biology : FG & B, 43(4), 234-246 (2006-02-10) Development of HIV-1 Nef vaccine components: immunogenicity study of Nef mutants lacking myristoylation and dileucine motif in mice.Xaioping Liang et al.Vaccine, 20(27-28), 3413-3421 (2002-09-06) A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8.Peter W Kim et al.Science (New York, N.Y.), 301(5640), 1725-1728 (2003-09-23) Autoinhibition of the ligand-binding site of GGA1/3 VHS domains by an internal acidic cluster-dileucine motif.Balraj Doray et al.Proceedings of the National Academy of Sciences of the United States of America, 99(12), 8072-8077 (2002-06-13) Utilization of dipeptides by Lactococcus lactis ssp. cremoris.A van Boven et al.Biochimie, 70(4), 535-542 (1988-04-01) Bioactive Properties of the Aqueous Extracts of Endophytic Fungi Associated with Scots Pine (Pinus sylvestris) Roots.Jenni Tienaho et al.Planta medica, 86(13-14), 1009-1024 (2020-06-11) Transpeptidation by porcine pepsin catalyzed by a noncovalent intermediate unique to its iso-mechanism.Y K Cho et al.The Journal of biological chemistry, 273(38), 24305-24308 (1998-09-12) Dileucine motif is sufficient for internalization and synaptic vesicle targeting of vesicular acetylcholine transporter.Lesley Colgan et al.Traffic (Copenhagen, Denmark), 8(5), 512-522 (2007-04-25) Intracellular targeting and retention of the glucose transporter GLUT4 by the perinuclear storage compartment involves distinct carboxyl-tail motifs.S Martinez-Arca et al.Journal of cell science, 113 ( Pt 10), 1705-1715 (2000-04-19) Sorting of mannose 6-phosphate receptors mediated by the GGAs.R Puertollano et al.Science (New York, N.Y.), 292(5522), 1712-1716 (2001-06-02) A novel compound, NK150460, exhibits selective antitumor activity against breast cancer cell lines through activation of aryl hydrocarbon receptor.Kazuteru Fukasawa et al.Molecular cancer therapeutics, 14(2), 343-354 (2014-12-20) Effect of dipeptides on the growth of Oenococcus oeni in synthetic medium deprived of amino acids.Pedro A Aredes Fernández et al.Current microbiology, 49(5), 361-365 (2004-10-16) Dual modulation on glial cells by tetrahydroxystilbene glucoside protects against dopamine neuronal loss.Yanzhen Zhou et al.Journal of neuroinflammation, 15(1), 161-161 (2018-05-29) Preferential utilization of dipeptides by Porphyromonas gingivalis.N Takahashi et al.Journal of dental research, 80(5), 1425-1429 (2001-07-05) Release of dipeptidyl peptidase IV (DPP-IV) inhibitory peptides from milk protein isolate (MPI) during enzymatic hydrolysis.Alice B Nongonierma et al.Food research international (Ottawa, Ont.), 94, 79-89 (2017-03-16) Stimulus frequency and intensity: critical determinants of opioid enhancement or inhibition of evoked methionine-enkephalin release.E Sublette et al.Brain research, 599(1), 165-170 (1992-12-18) Cell biology. 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