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2-Methyl-1H-imidazole-1-ethanol | CAS:1615-15-2
2-Methyl-1H-imidazole-1-ethanol
  • 名称:2-甲基-1H-咪唑-1-乙醇 | 2-Methyl-1H-imidazole-1-ethanol
  • CAS号:1615-15-2
  • 别名:1-(beta-Hydroxyethyl)-2-methylimidazole; 2-(2-Methyl-1H-imidazol-1-yl)ethanol; 2-Methyl-1-(2-hydroxyethyl)imidazole
  • 分子式:C6H10N2O
  • 分子量:126.16
  • EINESC号:

产品描述

物理化学性质

熔点 63-65 ºC (ethyl acetate )**
密度 1.12±0.1 g/cm3 (20 ºC

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Formation of alpha-hydroxyglutaric acid by Aspergillus glaucus.A S Bleiweis et al.Journal of bacteriology, 94(5), 1560-1564 (1967-11-01) The oncometabolite D-2-hydroxyglutarate induced by mutant IDH1 or -2 blocks osteoblast differentiation in vitro and in vivo.Johnny Suijker et al.Oncotarget, 6(17), 14832-14842 (2015-06-06) Robust detection of oncometabolic aberrations by 1H-13C heteronuclear single quantum correlation in intact biological specimens.Yasaman Barekatain et al.Communications biology, 3(1), 328-328 (2020-06-27) Abundance of d-2-hydroxyglutarate in G2/M is determined by FOXM1 in mutant IDH1-expressing cells.Kancharana Bala Bhaskara Rao et al.FEBS letters, 593(16), 2177-2193 (2019-06-19) Deficiency in SLC25A1, encoding the mitochondrial citrate carrier, causes combined D-2- and L-2-hydroxyglutaric aciduria.Benjamin Nota et al.American journal of human genetics, 92(4), 627-631 (2013-04-09) Inhibition of mutant IDH1 decreases D-2-HG levels without affecting tumorigenic properties of chondrosarcoma cell lines.Johnny Suijker et al.Oncotarget, 6(14), 12505-12519 (2015-04-22) Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China.Jiang-Han Wang et al.Proceedings of the National Academy of Sciences of the United States of America, 110(42), 17017-17022 (2013-10-02) Rapid separation of some common intermediates of microbial metabolism by thin-layer chromatography.A S Bleiweis et al.Analytical biochemistry, 20(2), 335-338 (1967-08-01) Oncometabolite D-2-Hydroxyglurate Directly Induces Epithelial-Mesenchymal Transition and is Associated with Distant Metastasis in Colorectal Cancer.Hugh Colvin et al.Scientific reports, 6, 36289-36289 (2016-11-09) The production of alpha-hydroxyglutaric acid from glutamic acid by cell-free preparations of Peptococcus aerogenes.W M Johnson et al.Canadian journal of biochemistry, 47(12), 1103-1107 (1969-12-01) 2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling.Xudong Fu et al.Cell metabolism, 22(3), 508-515 (2015-07-21) Validation of a hypoxia-inducible factor-1 alpha specimen collection procedure and quantitative enzyme-linked immunosorbent assay in solid tumor tissues.Sook Ryun Park et al.Analytical biochemistry, 459, 1-11 (2014-05-07) Registered report: Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.Brad Evans et al.eLife, 4, e07420-e07420 (2015-08-01) Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation.Peppi Koivunen et al.Nature, 483(7390), 484-488 (2012-02-22) Serum 2-hydroxyglutarate production in IDH1- and IDH2-mutated de novo acute myeloid leukemia: a study by the Acute Leukemia French Association group.Maxime Janin et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(4), 297-305 (2013-12-18)
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