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Clonazepam | CAS:1622-61-3
Clonazepam
  • 名称:氯安定; 氯硝安定; 氯硝西泮; 5-(2-氯苯基)-1,3-二氢-7-硝基-2H-1,4-苯并二氮杂卓-2-酮 | Clonazepam
  • CAS号:1622-61-3
  • 别名:5-(2-Chlorophenyl)-7-nitro-3H-1,4-benzodiazepin-2(1H)-one
  • 分子式:C15H10ClN3O3
  • 分子量:315.71
  • EINESC号:216-596-2

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物理化学性质

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安全说明书 S22;S24/25

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来源 SDS样本
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B, Analytical technologies in the biomedical and life sciences, 879(31), 3707-3713 (2011-11-02) Morphine withdrawal activates hypothalamic-pituitary-adrenal axis and heat shock protein 27 in the left ventricle: the role of extracellular signal-regulated kinase.E Martínez-Laorden et al.The Journal of pharmacology and experimental therapeutics, 342(3), 665-675 (2012-06-01) European field study of the efficacy and safety of the novel anthelmintic monepantel in sheep.M D Jones et al.The Veterinary record, 167(16), 610-613 (2011-01-25) Multiple strategies to prevent oxidative stress in Arabidopsis plants lacking the malate valve enzyme NADP-malate dehydrogenase.Inga Hebbelmann et al.Journal of experimental botany, 63(3), 1445-1459 (2011-12-06) The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models.Hong Zhao et al.Breast cancer research and treatment, 131(2), 425-436 (2011-03-12) Accumulation of monepantel and its sulphone derivative in tissues of nematode location in sheep: pharmacokinetic support to its excellent nematodicidal activity.A Lifschitz et al.Veterinary parasitology, 203(1-2), 120-126 (2014-03-22) Partial Purification of a Megadalton DNA Replication Complex by Free Flow Electrophoresis.Caroline M Li et al.PloS one, 11(12), e0169259-e0169259 (2016-12-31) In vitro and in vivo efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections.Lucienne Tritten et al.PLoS neglected tropical diseases, 5(12), e1457-e1457 (2012-01-05) Minimising the development of anthelmintic resistance, and optimising the use of the novel anthelmintic monepantel, for the sustainable control of nematode parasites in Australian sheep grazing systems.R J Dobson et al.Australian veterinary journal, 89(5), 160-166 (2011-04-19) Discovery and development of veterinary antiparasitic drugs: past, present and future.Debra J Woods et al.Future medicinal chemistry, 3(7), 887-896 (2011-06-08) The comparative efficacy of abamectin, monepantel and an abamectin/derquantel combination against fourth-stage larvae of a macrocyclic lactone-resistant Teladorsagia spp. isolate infecting sheep.S D George et al.Veterinary parasitology, 188(1-2), 190-193 (2012-03-31) Safety and efficacy against fourth-stage gastrointestinal nematode larvae, of monepantel in 6-week old lambs.P A Stein et al.Veterinary parasitology, 185(2-4), 339-342 (2011-11-15) Investigation of the metabolism of monepantel in ovine hepatocytes by UHPLC/MS/MS.Lucie Stuchlíková et al.Analytical and bioanalytical chemistry, 405(5), 1705-1712 (2012-11-28) Curcumin produces antidepressant effects via activating MAPK/ERK-dependent brain-derived neurotrophic factor expression in the amygdala of mice.Lin Zhang et al.Behavioural brain research, 235(1), 67-72 (2012-07-24) Potential drug development candidates for human soil-transmitted helminthiases.Piero Olliaro et al.PLoS neglected tropical diseases, 5(6), e1138-e1138 (2011-06-23) Haloperidol promotes mTORC1-dependent phosphorylation of ribosomal protein S6 via dopamine- and cAMP-regulated phosphoprotein of 32 kDa and inhibition of protein phosphatase-1.Alessandra Bonito-Oliva et al.Neuropharmacology, 72, 197-203 (2013-05-07) Monepantel irreversibly binds to and opens Haemonchus contortus MPTL-1 and Caenorhabditis elegans ACR-20 receptors.Roland Baur et al.Molecular pharmacology, 87(1), 96-102 (2014-10-30) Efficacy of monepantel and anthelmintic combinations against multiple-resistant Haemonchus contortus in sheep, including characterisation of the nematode isolate.K E Baker et al.Veterinary parasitology, 186(3-4), 513-517 (2011-12-16) MEK-ERK signaling dictates DNA-repair gene MGMT expression and temozolomide resistance of stem-like glioblastoma cells via the MDM2-p53 axis.Atsushi Sato et al.Stem cells (Dayton, Ohio), 29(12), 1942-1951 (2011-10-01) Activation of the extracellular signal-regulated kinase pathway contributes to the behavioral deficit of fragile x-syndrome.Xinglong Wang et al.Journal of neurochemistry, 121(4), 672-679 (2012-03-08) Naloxone-precipitated morphine withdrawal evokes phosphorylation of heat shock protein 27 in rat heart through extracellular signal-regulated kinase.P Almela et al.Journal of molecular and cellular cardiology, 51(1), 129-139 (2011-05-03) [New drugs for horses and production animals in 2010].I U Emmerich Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere, 39(6), 384-390 (2011-12-15) Isolation, identification, and culture optimization of a novel glycinonitrile-hydrolyzing fungus-Fusarium oxysporum H3.Jin-Song Gong et al.Applied biochemistry and biotechnology, 165(3-4), 963-977 (2011-07-02) Mitogen-activated protein kinase in the amygdala plays a critical role in lithium chloride-induced taste aversion learning.Bumsup Kwon et al.Neurobiology of learning and memory, 97(1), 132-139 (2011-11-17) A causative link between inner ear defects and long-term striatal dysfunction.Michelle W Antoine et al.Science (New York, N.Y.), 341(6150), 1120-1123 (2013-09-07) Establishing an efficacious dose rate of monepantel for treating gastrointestinal nematodes in llamas under field conditions.A M Dadak et al.The Veterinary record, 172(6), 155-155 (2013-01-08)
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