熔点	84 ºC**
密度	1.203±0.06 g/cm3 (20 º

没有数据	没有数据

来源	SDS样本
没有数据	没有数据

产品合成路线

更多

名称	CAS号

更多

文章

同行评议文献

Biodegradable amino acid-based poly(ester amine) with tunable immunomodulating properties and their in vitro and in vivo wound healing studies in diabetic rats' wounds.Mingyu He et al.Acta biomaterialia, 84, 114-132 (2018-12-07) Liposome-coated mesoporous silica nanoparticles loaded with L-cysteine for photoelectrochemical immunoassay of aflatoxin B1.Youxiu Lin et al.Mikrochimica acta, 185(6), 311-311 (2018-06-04) Fatty acid amide hydrolase: biochemistry, pharmacology, and therapeutic possibilities for an enzyme hydrolyzing anandamide, 2-arachidonoylglycerol, palmitoylethanolamide, and oleamide.C J Fowler et al.Biochemical pharmacology, 62(5), 517-526 (2001-10-05) Gastric bypass in morbid obese patients is associated with reduction in adipose tissue inflammation via N-oleoylethanolamide (OEA)-mediated pathways.Fabrizio Montecucco et al.Thrombosis and haemostasis, 113(4), 838-850 (2014-11-22) The interrelation between clinical presentation and neurophysiology of posthypoxic myoclonus.Jonathan C van Zijl et al.Annals of clinical and translational neurology, 5(4), 386-396 (2018-04-25) Echocardiography for prognostication during the resuscitation of intensive care unit patients with non-shockable rhythm cardiac arrest.Uri Adrian Prync Flato et al.Resuscitation, 92, 1-6 (2015-04-22) N-palmitoylethanolamide in the anterior cingulate cortex attenuates inflammatory pain behaviour indirectly via a CB1 receptor-mediated mechanism.Bright N Okine et al.Pain, 157(12), 2687-2696 (2016-09-21) Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes.Giovanni Appendino et al.Journal of medicinal chemistry, 52(9), 3001-3009 (2009-04-14) Acylamido analogs of endocannabinoids selectively inhibit cancer cell proliferation.Sumner Burstein et al.Bioorganic & medicinal chemistry, 16(22), 9644-9651 (2008-10-28) Potential Mechanisms Involved in Palmitoylethanolamide-Induced Vasodepressor Effects in Rats.Bruno A Marichal-Cancino et al.Journal of vascular research, 57(3), 152-163 (2020-04-06) Pulmonary Artery Imaging in Patients with Chronic Thromboembolic Pulmonary Hypertension: Comparison of Cone-Beam CT and 64-Row Multidetector CT.Jan B Hinrichs et al.Journal of vascular and interventional radiology : JVIR, 27(3), 361-368 (2016-01-25) Palmitoylethanolamide, endocannabinoids and related cannabimimetic compounds in protection against tissue inflammation and pain: potential use in companion animals.G Re et al.Veterinary journal (London, England : 1997), 173(1), 21-30 (2005-12-06) Modulation of neuropathic-pain-related behaviour by the spinal endocannabinoid/endovanilloid system.Katarzyna Starowicz et al.Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 367(1607), 3286-3299 (2012-10-31) The spatiotemporal expression changes of CB2R in the hippocampus of rats following pilocarpine-induced status epilepticus.Qiong Wu et al.Epilepsy research, 148, 8-16 (2018-10-15) Looking for a Treatment for the Early Stage of Alzheimer's Disease: Preclinical Evidence with Co-Ultramicronized Palmitoylethanolamide and Luteolin.Roberta Facchinetti et al.International journal of molecular sciences, 21(11) (2020-05-31) Association between Brain and Kidney Near-Infrared Spectroscopy and Early Postresuscitation Mortality in Asphyxiated Newborn Piglets.Anne Lee Solevåg et al.Neonatology, 112(1), 80-86 (2017-04-06) Pharmaceuticals and Surfactants from Alga-Derived Feedstock: Amidation of Fatty Acids and Their Derivatives with Amino Alcohols.Anastasia Tkacheva et al.ChemSusChem, 8(16), 2670-2680 (2015-07-23) Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis.Alfeu Zanotto-Filho et al.Molecular cancer therapeutics, 15(12), 3000-3014 (2016-09-18) Human lung-resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors.Rosaria I Staiano et al.Journal of leukocyte biology, 99(4), 531-540 (2015-10-16) Probable involvement of Ca(2+)-activated Cl(-) channels (CaCCs) in the activation of CB1 cannabinoid receptors.Thiago Roberto Lima Romero et al.Life sciences, 92(14-16), 815-820 (2012-11-06) Interactions between dietary oil treatments and genetic variants modulate fatty acid ethanolamides in plasma and body weight composition.Shuaihua Pu et al.The British journal of nutrition, 115(6), 1012-1023 (2016-01-26) Palmitoylethanolamide induces microglia changes associated with increased migration and phagocytic activity: involvement of the CB2 receptor.F Guida et al.Scientific reports, 7(1), 375-375 (2017-03-25) Magnetic bead/capture DNA/glucose-loaded nanoliposomes for amplifying the glucometer signal in the rapid screening of hepatitis C virus RNA.Haijian Tu et al.Analytical and bioanalytical chemistry, 410(16), 3661-3669 (2018-04-19) Relationship between seminal plasma levels of anandamide congeners palmitoylethanolamide and oleoylethanolamide and semen quality.Akwasi Atakora Amoako et al.Fertility and sterility, 102(5), 1260-1267 (2014-09-13) NMT1 and NMT3 N-Methyltransferase Activity Is Critical to Lipid Homeostasis, Morphogenesis, and Reproduction.Weihua Chen et al.Plant physiology, 177(4), 1605-1628 (2018-05-20) In vitro evaluation of structural analogs of diallyl sulfide as novel CYP2E1 inhibitors for their protective effect against xenobiotic-induced toxicity and HIV replication.Mohammad A Rahman et al.Toxicology letters, 292, 31-38 (2018-04-26) Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα.Mustafa A Karwad et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31(2), 469-481 (2016-09-15) Dose-Specific Effects of Di-Isononyl Phthalate on the Endocannabinoid System and on Liver of Female Zebrafish.Isabel Forner-Piquer et al.Endocrinology, 158(10), 3462-3476 (2017-09-25) Age-dependent plasticity in endocannabinoid modulation of pain processing through postnatal development.Charlie H-T Kwok et al.Pain, 158(11), 2222-2232 (2017-08-03) The anti-inflammatory mediator palmitoylethanolamide enhances the levels of 2-arachidonoyl-glycerol and potentiates its actions at TRPV1 cation channels.Stefania Petrosino et al.British journal of pharmacology, 173(7), 1154-1162 (2015-01-20) Micronized/ultramicronized palmitoylethanolamide displays superior oral efficacy compared to nonmicronized palmitoylethanolamide in a rat model of inflammatory pain.Daniela Impellizzeri et al.Journal of neuroinflammation, 11, 136-136 (2014-08-29) A Proximity Extension Assay (PEA)-based method for quantification of bevacizumab.Ivana Mikačić et al.Journal of pharmacological and toxicological methods, 92, 20-23 (2018-02-21) Novel quartz crystal microbalance immunodetection of aflatoxin B1 coupling cargo-encapsulated liposome with indicator-triggered displacement assay.Ying Tang et al.Analytica chimica acta, 1031, 161-168 (2018-08-19) Serum protein fingerprinting by PEA immunoassay coupled with a pattern-recognition algorithms distinguishes MGUS and multiple myeloma.Petra Schneiderova et al.Oncotarget, 8(41), 69408-69421 (2016-08-12) Mast cell-glia axis in neuroinflammation and therapeutic potential of the anandamide congener palmitoylethanolamide.Stephen D Skaper et al.Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 367(1607), 3312-3325 (2012-10-31) Different distributions of preproMCH and hypocretin/orexin in the forebrain of the pig (Sus scrofa domesticus).S Chometton et al.Journal of chemical neuroanatomy, 61-62, 72-82 (2014-08-16) The search for the palmitoylethanolamide receptor.Jesse LoVerme et al.Life sciences, 77(14), 1685-1698 (2005-06-21) Expression and significance of CDC25B, PED/PEA-15 in esophageal carcinoma.Ming Wang et al.Cancer biotherapy & radiopharmaceuticals, 30(3), 139-145 (2015-03-17) Dietary fatty acid composition impacts plasma fatty acid ethanolamide levels and body composition in golden Syrian hamsters.Jyoti Sihag et al.Food & function, 9(6), 3351-3362 (2018-05-31) Vapour-Deposited Cesium Lead Iodide Perovskites: Microsecond Charge Carrier Lifetimes and Enhanced Photovoltaic Performance.Eline M Hutter et al.ACS energy letters, 2(8), 1901-1908 (2017-08-31) Palmitoylethanolamide, endocannabinoids and related cannabimimetic compounds in protection against tissue inflammation and pain: potential use in companion animals.G Re et al.Veterinary journal (London, England : 1997), 173(1), 21-30 (2005-12-06) Electrophoretic analysis of polyamines in exhaled breath condensate based on gold-nanoparticles microextraction coupled with field-amplified sample stacking.Zheyan Chen et al.Talanta, 198, 480-486 (2019-03-17) Administration of palmitoylethanolamide (PEA) protects the neurovascular unit and reduces secondary injury after traumatic brain injury in mice.Akbar Ahmad et al.Brain, behavior, and immunity, 26(8), 1310-1321 (2012-08-14) Palmitoylethanolamide Reverses Paclitaxel-Induced Allodynia in Mice.Giulia Donvito et al.The Journal of pharmacology and experimental therapeutics, 359(2), 310-318 (2016-10-21) Δ9-Tetrahydrocannabinol induces endocannabinoid accumulation in mouse hepatocytes: antagonism by Fabp1 gene ablation.Avery L McIntosh et al.Journal of lipid research, 59(4), 646-657 (2018-02-08) Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia.F M Leweke et al.Translational psychiatry, 2, e94-e94 (2012-07-27) General Post-annealing Method Enables High-Efficiency Two-Dimensional Perovskite Solar Cells.Liang Yan et al.ACS applied materials & interfaces, 10(39), 33187-33197 (2018-09-08) High accuracy of proximity extension assay technology for the quantification of plasma brain natriuretic peptide.Mattia Arrigo et al.Journal of clinical laboratory analysis, 32(8), e22574-e22574 (2018-05-26) Administration of N-Acyl-Phosphatidylethanolamine Expressing Bacteria to Low Density Lipoprotein Receptor-/- Mice Improves Indices of Cardiometabolic Disease.Linda S May-Zhang et al.Scientific reports, 9(1), 420-420 (2019-01-25) Modulation of neuropathic-pain-related behaviour by the spinal endocannabinoid/endovanilloid system.Katarzyna Starowicz et al.Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 367(1607), 3286-3299 (2012-10-31) Pharmaceuticals and Surfactants from Alga-Derived Feedstock: Amidation of Fatty Acids and Their Derivatives with Amino Alcohols.Anastasia Tkacheva et al.ChemSusChem, 8(16), 2670-2680 (2015-07-23) Palmitoylethanolamide prevents metabolic alterations and restores leptin sensitivity in ovariectomized rats.G Mattace Raso et al.Endocrinology, 155(4), 1291-1301 (2014-01-17) A reliable protocol for colorimetric determination of iron oxide nanoparticle uptake by cells.Daiana K Deda et al.Analytical and bioanalytical chemistry, 409(28), 6663-6675 (2017-09-18) Proximity extension assay testing reveals novel diagnostic biomarkers of atypical parkinsonian syndromes.Edwin Jabbari et al.Journal of neurology, neurosurgery, and psychiatry, 90(7), 768-773 (2019-03-15) Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis.Alfeu Zanotto-Filho et al.Molecular cancer therapeutics, 15(12), 3000-3014 (2016-09-18) Separation of Key Biogenic Amines by Capillary Electrophoresis and Determination of Possible Indicators of Sport Fatigue in Athlete's Urine.Lili He et al.Journal of chromatographic science, 54(8), 1428-1434 (2016-05-04) Baicalin inhibits biofilm formation, attenuates the quorum sensing-controlled virulence and enhances Pseudomonas aeruginosa clearance in a mouse peritoneal implant infection model.Jing Luo et al.PloS one, 12(4), e0176883-e0176883 (2017-04-30) Relationship between seminal plasma levels of anandamide congeners palmitoylethanolamide and oleoylethanolamide and semen quality.Akwasi Atakora Amoako et al.Fertility and sterility, 102(5), 1260-1267 (2014-09-13) NMT1 and NMT3 N-Methyltransferase Activity Is Critical to Lipid Homeostasis, Morphogenesis, and Reproduction.Weihua Chen et al.Plant physiology, 177(4), 1605-1628 (2018-05-20) In vitro evaluation of structural analogs of diallyl sulfide as novel CYP2E1 inhibitors for their protective effect against xenobiotic-induced toxicity and HIV replication.Mohammad A Rahman et al.Toxicology letters, 292, 31-38 (2018-04-26) Quantitative profiling of endocannabinoids and relatedVasudev Kantae et al.Journal of lipid research, 58(3), 615-624 (2016-12-22) A nanocomposite consisting of silica-coated magnetite and phenyl-functionalized graphene oxide for extraction of polycyclic aromatic hydrocarbon from aqueous matrices.Shokouh Mahpishanian et al.Journal of environmental sciences (China), 55, 164-173 (2017-05-10) Maternal high fat high sugar diet disrupts olfactory behavior but not mucosa sensitivity in the offspring.Laëtitia Merle et al.Psychoneuroendocrinology, 104, 249-258 (2019-03-25) The search for the palmitoylethanolamide receptor.Jesse LoVerme et al.Life sciences, 77(14), 1685-1698 (2005-06-21) Different distributions of preproMCH and hypocretin/orexin in the forebrain of the pig (Sus scrofa domesticus).S Chometton et al.Journal of chemical neuroanatomy, 61-62, 72-82 (2014-08-16) IVIg for Treatment of Severe Refractory Heparin-Induced Thrombocytopenia.Anand Padmanabhan et al.Chest, 152(3), 478-485 (2017-04-22) Expression and significance of CDC25B, PED/PEA-15 in esophageal carcinoma.Ming Wang et al.Cancer biotherapy & radiopharmaceuticals, 30(3), 139-145 (2015-03-17) Dietary fatty acid composition impacts plasma fatty acid ethanolamide levels and body composition in golden Syrian hamsters.Jyoti Sihag et al.Food & function, 9(6), 3351-3362 (2018-05-31) Vapour-Deposited Cesium Lead Iodide Perovskites: Microsecond Charge Carrier Lifetimes and Enhanced Photovoltaic Performance.Eline M Hutter et al.ACS energy letters, 2(8), 1901-1908 (2017-08-31) Deranged endocannabinoid responses to hedonic eating in underweight and recently weight-restored patients with anorexia nervosa.Alessio Maria Monteleone et al.The American journal of clinical nutrition, 101(2), 262-269 (2015-02-04) Vestibulodynia: synergy between palmitoylethanolamide + transpolydatin and transcutaneous electrical nerve stimulation.Filippo Murina et al.Journal of lower genital tract disease, 17(2), 111-116 (2013-01-25) Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells.Masahiro Kita et al.Scientific reports, 9(1), 3135-3135 (2019-03-01) Biomechanical insult switches PEA-15 activity to uncouple its anti-apoptotic function and promote erk mediated tissue remodeling.Rachel E Exler et al.Experimental cell research, 340(2), 283-294 (2015-12-01) The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension.Michael Newnham et al.The European respiratory journal, 53(3) (2019-01-19) A quantitiative LC-MS/MS method for the measurement of arachidonic acid, prostanoids, endocannabinoids, N-acylethanolamines and steroids in human plasma.María Salomé Gachet et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 976-977, 6-18 (2014-12-02) Role of α-Dicarbonyl Compounds in the Inhibition Effect of Reducing Sugars on the Formation of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.Zhonghui Han et al.Journal of agricultural and food chemistry, 65(46), 10084-10092 (2017-10-31) A Proximity Extension Assay (PEA)-based method for quantification of bevacizumab.Ivana Mikačić et al.Journal of pharmacological and toxicological methods, 92, 20-23 (2018-02-21) Nanoscale Coatings for Ultralow Dose BMP-2-Driven Regeneration of Critical-Sized Bone Defects.Zhe A Cheng et al.Advanced science (Weinheim, Baden-Wurttemberg, Germany), 6(2), 1800361-1800361 (2019-01-30) Hydrothermal synthesis of carbon dots codoped with nitrogen and phosphorus as a turn-on fluorescent probe for cadmium(II).Liping Lin et al.Mikrochimica acta, 186(3), 147-147 (2019-02-04) AVE 0991 attenuates oxidative stress and neuronal apoptosis via Mas/PKA/CREB/UCP-2 pathway after subarachnoid hemorrhage in rats.Jun Mo et al.Redox biology, 20, 75-86 (2018-10-09) Novel quartz crystal microbalance immunodetection of aflatoxin B1 coupling cargo-encapsulated liposome with indicator-triggered displacement assay.Ying Tang et al.Analytica chimica acta, 1031, 161-168 (2018-08-19) Serum protein fingerprinting by PEA immunoassay coupled with a pattern-recognition algorithms distinguishes MGUS and multiple myeloma.Petra Schneiderova et al.Oncotarget, 8(41), 69408-69421 (2016-08-12) Mast cell-glia axis in neuroinflammation and therapeutic potential of the anandamide congener palmitoylethanolamide.Stephen D Skaper et al.Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 367(1607), 3312-3325 (2012-10-31) Scp-2/Scp-x ablation in Fabp1 null mice differentially impacts hepatic endocannabinoid level depending on dietary fat.Gregory G Martin et al.Archives of biochemistry and biophysics, 650, 93-102 (2018-05-16) Characteristics of jugular bulb oxygen saturation in patients after cardiac arrest: A prospective study.E Wallin et al.Acta anaesthesiologica Scandinavica, 62(9), 1237-1245 (2018-05-26) JZL184 is anti-hyperalgesic in a murine model of cisplatin-induced peripheral neuropathy.Iryna A Khasabova et al.Pharmacological research, 90, 67-75 (2014-10-12) The Effect of Orally Dosed Levagen+™ (palmitoylethanolamide) on Exercise Recovery in Healthy Males-A Double-Blind, Randomized, Placebo-Controlled Study.Alistair Mallard et al.Nutrients, 12(3) (2020-02-29) Enhancement of Antihyperalgesia by the Coadministration of N-palmitoylethanolamide and Acetaminophen in Diabetic Rats.Myrna Déciga-Campos et al.Drug development research, 76(5), 228-234 (2015-07-29) Cannabidiol and palmitoylethanolamide are anti-inflammatory in the acutely inflamed human colon.Daniel G Couch et al.Clinical science (London, England : 1979), 131(21), 2611-2626 (2017-09-29) Chemical genetics reveals a complex functional ground state of neural stem cells.Phedias Diamandis et al.Nature chemical biology, 3(5), 268-273 (2007-04-10) Cannabidiol and palmitoylethanolamide are anti-inflammatory in the acutely inflamed human colon.Daniel G Couch et al.Clinical science (London, England : 1979), 131(21), 2611-2626 (2017-09-29) Central and peripheral endocannabinoids and cognate acylethanolamides in humans: association with race, adiposity, and energy expenditure.Reiner Jumpertz et al.The Journal of clinical endocrinology and metabolism, 96(3), 787-791 (2010-12-24) Non-adrenergic vasoconstriction and vasodilatation of guinea-pig aorta by β-phenylethylamine and amphetamine - Role of nitric oxide determined with L-NAME and NO scavengers.Kenneth J Broadley et al.European journal of pharmacology, 818, 198-205 (2017-10-28) Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism.Whitney H Brown et al.Proceedings of the National Academy of Sciences of the United States of America, 109(37), 14966-14971 (2012-08-23) Effectiveness of palmitoylethanolamide on endothelial dysfunction in ocular hypertensive patients: a randomized, placebo-controlled cross-over study.Ernesto Strobbe et al.Investigative ophthalmology & visual science, 54(2), 968-973 (2013-01-12) Nanoscale Coatings for Ultralow Dose BMP-2-Driven Regeneration of Critical-Sized Bone Defects.Zhe A Cheng et al.Advanced science (Weinheim, Baden-Wurttemberg, Germany), 6(2), 1800361-1800361 (2019-01-30) Scp-2/Scp-x ablation in Fabp1 null mice differentially impacts hepatic endocannabinoid level depending on dietary fat.Gregory G Martin et al.Archives of biochemistry and biophysics, 650, 93-102 (2018-05-16) Characteristics of jugular bulb oxygen saturation in patients after cardiac arrest: A prospective study.E Wallin et al.Acta anaesthesiologica Scandinavica, 62(9), 1237-1245 (2018-05-26) JZL184 is anti-hyperalgesic in a murine model of cisplatin-induced peripheral neuropathy.Iryna A Khasabova et al.Pharmacological research, 90, 67-75 (2014-10-12) New insights in mast cell modulation by palmitoylethanolamide.D De Filippis et al.CNS & neurological disorders drug targets, 12(1), 78-83 (2013-02-12) Synergistic antinociceptive interaction between palmitoylethanolamide and tramadol in the mouse formalin test.Myrna Déciga-Campos et al.European journal of pharmacology, 765, 68-74 (2015-08-25) Altered Waste Disposal System in Aging and Alzheimer's Disease: Focus on Astrocytic Aquaporin-4.Marta Valenza et al.Frontiers in pharmacology, 10, 1656-1656 (2020-02-18) Neuroprotective activities of palmitoylethanolamide in an animal model of Parkinson's disease.Emanuela Esposito et al.PloS one, 7(8), e41880-e41880 (2012-08-23) Characterization and Performance of Hollow Silica for Adsorption of Amoxicillin in Aqueous Solutions.Hongxiang Ou et al.Water environment research : a research publication of the Water Environment Federation, 89(4), 348-356 (2017-04-06) Study of sample preparation for determination of endocannabinoids and analogous compounds in human serum by LC-MS/MS in MRM mode.D Luque-Córdoba et al.Talanta, 185, 602-610 (2018-05-16) Randomised clinical trial: the analgesic properties of dietary supplementation with palmitoylethanolamide and polydatin in irritable bowel syndrome.C Cremon et al.Alimentary pharmacology & therapeutics, 45(7), 909-922 (2017-02-07) Chemical genetics reveals a complex functional ground state of neural stem cells.Phedias Diamandis et al.Nature chemical biology, 3(5), 268-273 (2007-04-10) Mapping QTLs for physiological and biochemical traits related to grain yield under control and terminal heat stress conditions in bread wheat (Triticum aestivum L.).Faramarz Sohrabi Chah Hassan et al.Physiology and molecular biology of plants : an international journal of functional plant biology, 24(6), 1231-1243 (2018-11-15) Solution-processed perovskite light emitting diodes with efficiency exceeding 15% through additive-controlled nanostructure tailoring.Muyang Ban et al.Nature communications, 9(1), 3892-3892 (2018-09-27) N-Palmitoylethanolamine-oxazoline (PEA-OXA): A new therapeutic strategy to reduce neuroinflammation, oxidative stress associated to vascular dementia in an experimental model of repeated bilateral common carotid arteries occlusion.Daniela Impellizzeri et al.Neurobiology of disease, 125, 77-91 (2019-01-21) Negative pressure wound therapy reduces the motility of Pseudomonas aeruginosa and enhances wound healing in a rabbit ear biofilm infection model.Wang Guoqi et al.Antonie van Leeuwenhoek, 111(9), 1557-1570 (2018-02-23) Polymeric Nanocomposites and Nanocoatings for Food Packaging: A Review.Cornelia Vasile Materials (Basel, Switzerland), 11(10) (2018-09-29) Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice.Sébastien Lenglet et al.Arteriosclerosis, thrombosis, and vascular biology, 33(2), 215-223 (2012-12-18) Neurophysiological and neuroradiological multimodal approach for early poor outcome prediction after cardiac arrest.Maenia Scarpino et al.Resuscitation, 129, 114-120 (2018-04-22) Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products.Sarah Nicolai et al.Science immunology, 5(43) (2020-01-05) Reduction of ischemic brain injury by administration of palmitoylethanolamide after transient middle cerebral artery occlusion in rats.Akbar Ahmad et al.Brain research, 1477, 45-58 (2012-10-11) Toward Increasing Micropore Volume between Hybrid Layered Perovskites with Silsesquioxane Interlayers.Sho Kataoka et al.Langmuir : the ACS journal of surfaces and colloids, 34(14), 4166-4172 (2018-03-20) Abnormal pulmonary endothelial cells may underlie the enigmatic pathogenesis of chronic thromboembolic pulmonary hypertension.Olaf Mercier et al.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 36(3), 305-314 (2016-10-30) Uncovering the psychoactivity of a cannabinoid from liverworts associated with a legal high.A Chicca et al.Science advances, 4(10), eaat2166-eaat2166 (2018-11-07) Comparison of whole animal costs of protein synthesis among polar and temperate populations of the same species of gammarid amphipod.S P S Rastrick et al.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 207, 100-106 (2017-03-07) The incidence and characteristics of 3-month mortality after intraoperative cardiac arrest in adults.M Hur et al.Acta anaesthesiologica Scandinavica, 61(9), 1095-1104 (2017-08-12) Investigation of Naturally Occurring Single-Nucleotide Variants in Human TAAR1.Jessica Mühlhaus et al.Frontiers in pharmacology, 8, 807-807 (2017-12-12) Limbic Neurons Shape Sex Recognition and Social Behavior in Sexually Naive Males.Daniel W Bayless et al.Cell, 176(5), 1190-1205 (2019-02-05) Acute administration of beta-caryophyllene prevents endocannabinoid system activation during transient common carotid artery occlusion and reperfusion.Laura Poddighe et al.Lipids in health and disease, 17(1), 23-23 (2018-02-07) Foragers of sympatric Asian honey bee species intercept competitor signals by avoiding benzyl acetate from Apis cerana alarm pheromone.Ping Wen et al.Scientific reports, 7(1), 6721-6721 (2017-07-29) Tumor-Targeting Anti-MicroRNA-155 Delivery Based on Biodegradable Poly(ester amine) and Hyaluronic Acid Shielding for Lung Cancer Therapy.Yi Yang et al.Chemphyschem : a European journal of chemical physics and physical chemistry, 19(16), 2058-2069 (2018-03-01) Pharmacological properties of rat brain fatty acid amidohydrolase in different subcellular fractions using palmitoylethanolamide as substrate.G Tiger et al.Biochemical pharmacology, 59(6), 647-653 (2000-02-25) Targeting brain and peripheral plasticity of the lipidome in acute kainic acid-induced epileptic seizures in mice via quantitative mass spectrometry.Raissa Lerner et al.Biochimica et biophysica acta, 1862(2), 255-267 (2016-11-23) Measurement of palmitoylethanolamide and other N-acylethanolamines during physiological and pathological conditions.Michiel G J Balvers et al.CNS & neurological disorders drug targets, 12(1), 23-33 (2013-02-12) Effects of dietary CLA on n-3 HUFA score and N-acylethanolamides biosynthesis in the liver of obese Zucker rats.Antonio Piras et al.Prostaglandins, leukotrienes, and essential fatty acids, 98, 15-19 (2015-04-29) Composite contributions of cerebrospinal fluid GABAergic neurosteroids, neuropeptide Y and interleukin-6 to PTSD symptom severity in men with PTSD.Byung Kil Kim et al.Neurobiology of stress, 12, 100220-100220 (2020-05-22) Palmitoylethanolamide reduces early renal dysfunction and injury caused by experimental ischemia and reperfusion in mice.Rosanna Di Paola et al.Shock (Augusta, Ga.), 38(4), 356-366 (2012-07-10) Palmitoylethanolamide in the treatment of chronic pain caused by different etiopathogenesis.Antonio Gatti et al.Pain medicine (Malden, Mass.), 13(9), 1121-1130 (2012-08-01) Definition of a Family of Nonmobile Colistin Resistance (NMCR-1) Determinants Suggests Aquatic Reservoirs for MCR-4.Huimin Zhang et al.Advanced science (Weinheim, Baden-Wurttemberg, Germany), 6(11), 1900038-1900038 (2019-06-11) Impact of a Bacillus Direct-Fed Microbial on Growth Performance, Intestinal Barrier Integrity, Necrotic Enteritis Lesions, and Ileal Microbiota in Broiler Chickens Using a Laboratory Challenge Model.Daniel Hernandez-Patlan et al.Frontiers in veterinary science, 6, 108-108 (2019-05-21) Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy.Rita Citraro et al.Neuropharmacology, 69, 115-126 (2012-12-05) Fatty acid binding protein deletion suppresses inflammatory pain through endocannabinoid/N-acylethanolamine-dependent mechanisms.Martin Kaczocha et al.Molecular pain, 11, 52-52 (2015-08-28) Wash or wipe? A comparative study of skin physiological changes between water washing and wiping after skin cleaning.K Ogai et al.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 23(4), 519-524 (2017-03-16) Joint Synovial Fluid Metabolomics Method to Decipher the Metabolic Mechanisms of Adjuvant Arthritis and Geniposide Intervention.Xiang Zhan et al.Journal of proteome research, 19(9), 3769-3778 (2020-08-14) Glia and mast cells as targets for palmitoylethanolamide, an anti-inflammatory and neuroprotective lipid mediator.Stephen D Skaper et al.Molecular neurobiology, 48(2), 340-352 (2013-07-03) N-acylethanolamine acid amidase (NAAA), a new path to unleash PPAR-mediated analgesia.Bradley K Taylor Pain, 154(3), 326-327 (2013-01-22) Capture and Release of Cancer Cells by Combining On-Chip Purification and Off-Chip Enzymatic Treatment.Xiaolei Yu et al.ACS applied materials & interfaces, 7(43), 24001-24007 (2015-10-22) Seasonal Changes in Endocannabinoid Concentrations between Active and Hibernating Marmots (Marmota flaviventris).Emily A Mulawa et al.Journal of biological rhythms, 33(4), 388-401 (2018-06-05) Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.Jing Yuan et al.Nature chemical biology, 5(10), 765-771 (2009-09-08) Palmitoylethanolamide Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis in Rats.Masatsugu Ohara et al.Frontiers in pharmacology, 9, 709-709 (2018-07-31) Chemosensory perception is specifically impaired in Parkinson's disease.Cécilia Tremblay et al.Parkinsonism & related disorders, 57, 68-71 (2018-08-14) Palmitoylethanolamide in homeostatic and traumatic central nervous system injuries.Emanuela Esposito et al.CNS & neurological disorders drug targets, 12(1), 55-61 (2013-02-12) Association Between Therapeutic Hypothermia and Outcomes in Patients with Non-shockable Out-of-Hospital Cardiac Arrest Developed After Emergency Medical Service Arrival (SOS-KANTO 2012 Analysis Report).Minoru Yoshida et al.Neurocritical care, 30(2), 429-439 (2018-10-03) Engineered Coatings for Titanium Implants To Present Ultralow Doses of BMP-7.Mohammed Al-Jarsha et al.ACS biomaterials science & engineering, 4(5), 1812-1819 (2018-06-05) Radiosynthesis, in vitro and in vivo evaluation of 123I-labeled anandamide analogues for mapping brain FAAH.Leonie Wyffels et al.Bioorganic & medicinal chemistry, 17(1), 49-56 (2008-12-05) Chronic exposure to cannabinoids during adolescence causes long-lasting behavioral deficits in adult mice.J Tomas-Roig et al.Addiction biology, 22(6), 1778-1789 (2016-09-01) Regulation of GPR119 receptor activity with endocannabinoid-like lipids.Samreen K Syed et al.American journal of physiology. Endocrinology and metabolism, 303(12), E1469-E1478 (2012-10-18) The influence of poly(ester amide) on the structural and functional features of 3D additive manufactured poly(ε-caprolactone) scaffolds.Antonio Gloria et al.Materials science & engineering. C, Materials for biological applications, 98, 994-1004 (2019-03-01) Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice.F Guida et al.Molecular brain, 8, 47-47 (2015-08-12) Effects of tumour necrosis factor α upon the metabolism of the endocannabinoid anandamide in prostate cancer cells.Jessica Karlsson et al.PloS one, 12(9), e0185011-e0185011 (2017-09-15) Cocaine-Induced Reinstatement of Cocaine Seeking Provokes Changes in the Endocannabinoid and N-Acylethanolamine Levels in Rat Brain Structures.Beata Bystrowska et al.Molecules (Basel, Switzerland), 24(6) (2019-03-25) Using personas to exploit environmental attitudes and behaviour in sustainable product design.Margaret Carey et al.Applied ergonomics, 78, 97-109 (2019-05-03) Critical role of a pre-purge setup in the thermal desorption analysis of volatile organic compounds by gas chromatography with mass spectrometry.Yong-Hyun Kim et al.Journal of separation science, 38(14), 2455-2462 (2015-05-12) Simultaneous determination of β-agonists on hexagonal boron nitride nanosheets/multi-walled carbon nanotubes nanocomposite modified glassy carbon electrode.Mehmet Lütfi Yola et al.Materials science & engineering. C, Materials for biological applications, 96, 669-676 (2019-01-05) Pyridostigmine bromide exposure creates chronic, underlying neuroimmune disruption in the gastrointestinal tract and brain that alters responses to palmitoylethanolamide in a mouse model of Gulf War Illness.Siomara Hernandez et al.Neuropharmacology, 179, 108264-108264 (2020-08-08) Evaluation of endogenous fatty acid amides and their synthetic analogues as potential anti-inflammatory leads.Hung The Dang et al.Bioorganic & medicinal chemistry, 19(4), 1520-1527 (2011-01-25) Calcium-dependent generation of N-acylethanolamines and lysophosphatidic acids by glycerophosphodiesterase GDE7.Iffat Ara Sonia Rahman et al.Biochimica et biophysica acta, 1861(12 Pt A), 1881-1892 (2016-10-22) N-Acylethanolamine-hydrolyzing acid amidase inhibition increases colon N-palmitoylethanolamine levels and counteracts murine colitis.Mireille Alhouayek et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(2), 650-661 (2014-11-12) A quantitative study on splice variants of N-acylethanolamine acid amidase in human prostate cancer cells and other cells.Yuma Sakura et al.Biochimica et biophysica acta, 1861(12 Pt A), 1951-1958 (2016-10-22) Glycerophosphodiesterase GDE4 as a novel lysophospholipase D: a possible involvement in bioactive N-acylethanolamine biosynthesis.Kazuhito Tsuboi et al.Biochimica et biophysica acta, 1851(5), 537-548 (2015-01-18) TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury.Shrilatha Balakrishna et al.American journal of physiology. Lung cellular and molecular physiology, 307(2), L158-L172 (2014-05-20) Effect of PEA on LPS inflammatory action in human adipocytes.Laurence Hoareau et al.Cytokine, 34(5-6), 291-296 (2006-08-04) Ratiometric fluorescence detection of riboflavin based on fluorescence resonance energy transfer from nitrogen and phosphorus co-doped carbon dots to riboflavin.Liping Lin et al.Analytical and bioanalytical chemistry, 411(13), 2803-2808 (2019-03-29) Cell migration on material-driven fibronectin microenvironments.E Grigoriou et al.Biomaterials science, 5(7), 1326-1333 (2017-06-15) CB1 receptor activation induces intracellular Ca2+ mobilization and 2-arachidonoylglycerol release in rodent spinal cord astrocytes.Zoltán Hegyi et al.Scientific reports, 8(1), 10562-10562 (2018-07-14) Sterol Carrier Protein-2/Sterol Carrier Protein-x/Fatty Acid Binding Protein-1 Ablation Impacts Response of Brain Endocannabinoid to High-Fat Diet.Gregory G Martin et al.Lipids, 54(10), 583-601 (2019-09-06) Endocannabinoids and sleep.Oscar Prospéro-García et al.Neuroscience and biobehavioral reviews, 71, 671-679 (2016-10-21) PolymorphismMelania Melis et al.Frontiers in physiology, 8, 1006-1006 (2017-12-23) Involvement of the endocannabinoid system in the physiological response to transient common carotid artery occlusion and reperfusion.Marina Quartu et al.Lipids in health and disease, 16(1), 14-14 (2017-01-21) Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS.Carolin Hacker et al.Nature communications, 9(1), 4366-4366 (2018-10-21) PPAR-α acutely inhibits functional activity of ASICs in rat dorsal root ganglion neurons.Jing Wu et al.Oncotarget, 8(54), 93051-93062 (2017-12-02) Investigating Pervaporation for In Situ Acetone Removal as Process Intensification Tool in ω-Transaminase Catalyzed Chiral Amine Synthesis.Yamini Satyawali et al.Biotechnology progress, 35(1), e2731-e2731 (2018-10-14) Superparamagnetic core-shells anchored onto graphene oxide grafted with phenylethyl amine as a nano-adsorbent for extraction and enrichment of organophosphorus pesticides from fruit, vegetable and water samples.Shokouh Mahpishanian et al.Journal of chromatography. A, 1406, 48-58 (2015-07-02) Electrochemiluminescence sensor based on upconversion nanoparticles and oligoaniline-crosslinked gold nanoparticles imprinting recognition sites for the determination of dopamine.Ying Gu et al.Biosensors & bioelectronics, 128, 129-136 (2019-01-19) CB1 and CB2 cannabinoid receptor agonists induce peripheral antinociception by activation of the endogenous noradrenergic system.Thiago R L Romero et al.Anesthesia and analgesia, 116(2), 463-472 (2013-01-11) Palmitoylethanolamide improves colon inflammation through an enteric glia/toll like receptor 4-dependent PPAR-α activation.Giuseppe Esposito et al.Gut, 63(8), 1300-1312 (2013-10-02) Inhibition of anandamide hydrolysis attenuates nociceptor sensitization in a murine model of chemotherapy-induced peripheral neuropathy.Megan L Uhelski et al.Journal of neurophysiology, 113(5), 1501-1510 (2014-12-17) Purification and characterization of a novel NADPH-dependent 2-aminoacetophenone reductase from Arthrobacter sulfureus.Guogang Zhao et al.Journal of bioscience and bioengineering, 119(6), 648-651 (2014-12-10) Investigation of changes in endocannabinoids and N-acylethanolamides in biofluids, and their correlations with female infertility.Jun Ding et al.Journal of chromatography. A, 1509, 16-25 (2017-06-22) Efficacy of chandelier illumination for combined cataract operation and penetrating keratoplasty.Shunji Yokokura et al.Cornea, 34(3), 275-278 (2015-01-08) Increased plasma concentrations of palmitoylethanolamide, an endogenous fatty acid amide, affect oxidative damage of human low-density lipoproteins: an in vitro study.Giovanna Zolese et al.Atherosclerosis, 182(1), 47-55 (2005-08-24) Activation and desensitization of TRPV1 channels in sensory neurons by the PPARα agonist palmitoylethanolamide.Paolo Ambrosino et al.British journal of pharmacology, 168(6), 1430-1444 (2012-10-23) Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner.Torsten Lowin et al.Arthritis research & therapy, 17, 321-321 (2015-11-17) Genetic Polymorphisms Affect Mouse and Human Trace Amine-Associated Receptor 1 Function.Xiao Shi et al.PloS one, 11(3), e0152581-e0152581 (2016-04-01) The palmitoylethanolamide and oleamide enigmas : are these two fatty acid amides cannabimimetic?D M Lambert et al.Current medicinal chemistry, 6(8), 757-773 (1999-09-02) Effect of diet on tissue levels of palmitoylethanolamide.Harald S Hansen CNS & neurological disorders drug targets, 12(1), 17-25 (2013-02-12) Downregulation of PEA-15 reverses G1 arrest, and nuclear and chromatin changes of senescence phenotype via pErk1/2 translocation to nuclei.Yun Yeong Lee et al.Cellular signalling, 27(6), 1102-1109 (2015-03-01) The palmitoylethanolamide family: a new class of anti-inflammatory agents?Didier M Lambert et al.Current medicinal chemistry, 9(6), 663-674 (2002-04-12) Novel Campylobacter concisus lipooligosaccharide is a determinant of inflammatory potential and virulence.Katja Brunner et al.Journal of lipid research, 59(10), 1893-1905 (2018-07-28) Synthesis and antituberculosis activity of new fatty acid amides.Caroline Da Ros Montes D'Oca et al.Bioorganic & medicinal chemistry letters, 20(17), 5255-5257 (2010-07-30) Effects of Solvent Crystallization in Swollen net-Poly(ethyl acrylate) α Relaxation Dynamics.Andreas T Stathopoulos et al.The journal of physical chemistry. B, 120(51), 13206-13217 (2016-12-15) Sodium butyrate and its synthetic amide derivative modulate nociceptive behaviors in mice.Roberto Russo et al.Pharmacological research, 103, 279-291 (2015-12-18) The human serum metabolome.Nikolaos Psychogios et al.PloS one, 6(2), e16957-e16957 (2011-03-02) CRISPR-Mediated Knockout of Cybb in NSG Mice Establishes a Model of Chronic Granulomatous Disease for Human Stem-Cell Gene Therapy Transplants.Colin L Sweeney et al.Human gene therapy, 28(7), 565-575 (2017-03-08) Olfactory processing: detection of rapid changes.Ilona Croy et al.Chemical senses, 40(5), 351-355 (2015-04-26) Taste disorders are partly genetically determined: Role of the TAS2R38 gene, a pilot study.Melania Melis et al.The Laryngoscope, 129(9), E307-E312 (2019-01-25) Efficacy of budesonide-loaded mesoporous silica microparticles capped with a bulky azo derivative in rats with TNBS-induced colitis.Daniel Ferri et al.International journal of pharmaceutics, 561, 93-101 (2019-03-01) Baseline anandamide levels and body weight impact the weight loss effect of CB1 receptor antagonism in male rats.Cecilia Karlsson et al.Endocrinology, 156(4), 1237-1241 (2014-12-31) Palmitoylethanolamide and other anandamide congeners. Proposed role in the diseased brain.Harald S Hansen Experimental neurology, 224(1), 48-55 (2010-04-01) Palmitoylethanolamide counteracts substance P-induced mast cell activation in vitro by stimulating diacylglycerol lipase activity.Stefania Petrosino et al.Journal of neuroinflammation, 16(1), 274-274 (2019-12-28) Interaction of intraocular lenses with fibronectin and human lens epithelial cells: Effect of chemical composition and aging.Lionel Tortolano et al.Journal of biomedical materials research. Part A, 103(12), 3843-3851 (2015-06-27) Effects of repeated long-term psychosocial stress and acute cannabinoid exposure on mouse corticostriatal circuitries: Implications for neuropsychiatric disorders.Jordi Tomas-Roig et al.CNS neuroscience & therapeutics, 24(6), 528-538 (2018-02-02) Methylphosphonate Oxidation in Prochlorococcus Strain MIT9301 Supports Phosphate Acquisition, Formate Excretion, and Carbon Assimilation into Purines.Oscar A Sosa et al.Applied and environmental microbiology, 85(13) (2019-04-28) Palmitoylethanolamide is a disease-modifying agent in peripheral neuropathy: pain relief and neuroprotection share a PPAR-alpha-mediated mechanism.L Di Cesare Mannelli et al.Mediators of inflammation, 2013, 328797-328797 (2013-03-28) Palmitoylethanolamide is a new possible pharmacological treatment for the inflammation associated with trauma.Emanuela Esposito et al.Mini reviews in medicinal chemistry, 13(2), 237-255 (2012-06-16) Protective effect of palmitoylethanolamide in a rat model of cystitis.Federica Pessina et al.The Journal of urology, 193(4), 1401-1408 (2014-12-03) Elevated anandamide and related N-acylethanolamine levels occur in the peripheral blood of women with ectopic pregnancy and are mirrored by changes in peripheral fatty acid amide hydrolase activity.Alpha K Gebeh et al.The Journal of clinical endocrinology and metabolism, 98(3), 1226-1234 (2013-02-02) An apPEAling new therapeutic for ulcerative colitis?Declan P McKernan et al.Gut, 63(8), 1207-1208 (2013-10-25) Efficacy of β-phenylethylamine as a novel anti-microbial and application as a liquid catheter flush.Meredith Schroeder et al.Journal of medical microbiology, 67(12), 1778-1788 (2018-10-17) Endocannabinoid 2-arachidonoylglycerol is elevated in the coronary circulation during acute coronary syndrome.Julian Jehle et al.PloS one, 14(12), e0227142-e0227142 (2019-12-31) Targeted ultrasound molecular imaging in mouse atherosclerotic plaque model.J Zhou et al.Journal of biological regulators and homeostatic agents, 31(3), 697-703 (2017-09-29) Development, functional characterization and validation of methodology for GMP-compliant manufacture of phagocytic macrophages: A novel cellular therapeutic for liver cirrhosis.Alasdair R Fraser et al.Cytotherapy, 19(9), 1113-1124 (2017-07-05) A simple method for simultaneous determination of N-arachidonoylethanolamine, N-oleoylethanolamine, N-palmitoylethanolamine and 2-arachidonoylglycerol in human cells.Igor Ivanov et al.Analytical and bioanalytical chemistry, 407(6), 1781-1787 (2014-12-19) Exercise training and high-fat diet elicit endocannabinoid system modifications in the rat hypothalamus and hippocampus.François-Xavier Gamelin et al.Journal of physiology and biochemistry, 73(3), 335-347 (2017-03-12) Cloning and pharmacological characterization of the rat CB(2) cannabinoid receptor.G Griffin et al.The Journal of pharmacology and experimental therapeutics, 292(3), 886-894 (2000-02-25) Tunable Enzymatic Activity and Enhanced Stability of Cellulase Immobilized in Biohybrid Nanogels.Huan Peng et al.Biomacromolecules, 17(11), 3619-3631 (2016-09-20) Systemic administration of serotonin exacerbates abdominal pain and colitis via interaction with the endocannabinoid system.Maciej Salaga et al.Biochemical pharmacology, 161, 37-51 (2019-01-07)

备注