沸点	47-48 ºC (0.1 mmHg)
密度	1.048
折射率	1.537

危险品标志	C
危险类别码	R34
安全说明书	S26;S36/37/39;S45

来源	SDS样本
Alfa-Aesar	浏览或下载
Sigma-Aldrich	浏览或下载
Apollo	浏览或下载

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Effects of hypericin and a chlorin based photosensitizer alone or in combination in squamous cell carcinoma cells in the dark.Emina Besic Gyenge et al.Photodiagnosis and photodynamic therapy, 9(4), 321-331 (2012-12-04) Transport and accumulation of PVP-Hypericin in cancer and normal cells characterized by image correlation spectroscopy techniques.Rozhin Penjweini et al.Biochimica et biophysica acta, 1843(5), 855-865 (2014-02-01) Development of a new LDL-based transport system for hydrophobic/amphiphilic drug delivery to cancer cells.Veronika Huntosova et al.International journal of pharmaceutics, 436(1-2), 463-471 (2012-07-21) The pro-apoptotic and anti-invasive effects of hypericin-mediated photodynamic therapy are enhanced by hyperforin or aristoforin in HT-29 colon adenocarcinoma cells.Martina Šemeláková et al.Journal of photochemistry and photobiology. 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B, 117(5), 1280-1286 (2013-01-05) PAL inhibitor evokes different responses in two Hypericum species.Bořivoj Klejdus et al.Plant physiology and biochemistry : PPB, 63, 82-88 (2012-12-21) Elicitation of secondary metabolism in Hypericum perforatum by rhizosphere bacteria and derived elicitors in seedlings and shoot cultures.F Javier Gutiérrez Mañero et al.Pharmaceutical biology, 50(10), 1201-1209 (2012-08-21) Modifying excitation light dose of novel photosensitizer PVP-Hypericin for photodynamic diagnosis and therapy.Rozhin Penjweini et al.Journal of photochemistry and photobiology. B, Biology, 120, 120-129 (2013-02-05) Pattern of sensitivity of progressive cutaneous squamous cell carcinoma cells to UVB and oxidative stress-induced cell death.Kathleen Barrette et al.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 12(1), 104-110 (2012-06-23) Enhanced radiation sensitivity and radiation recall dermatitis (RRD) after hypericin therapy -- case report and review of literature.Kurt Putnik et al.Radiation oncology (London, England), 1, 32-32 (2006-09-05) Apoptotic and anti-apoptotic signaling pathways induced by photodynamic therapy with hypericin.P Agostinis et al.Advances in enzyme regulation, 40, 157-182 (2000-06-01) Structural and photophysical properties of peptide micro/nanotubes functionalized with hypericin.Márcia I Souza et al.The journal of physical chemistry. B, 117(9), 2605-2614 (2013-02-14) A basic study on hypericin-PDT in vitro.Nobue Nakajima et al.Photodiagnosis and photodynamic therapy, 9(3), 196-203 (2012-09-11) Bcl-2 proapoptotic proteins distribution in U-87 MG glioma cells before and after hypericin photodynamic action.Lucia Balogová et al.General physiology and biophysics, 32(2), 179-187 (2013-03-13) Delivery of hypericin for photodynamic applications.Constance Lay Lay Saw et al.Cancer letters, 241(1), 23-30 (2005-11-24) Antibiotic-free nanotherapeutics: hypericin nanoparticles thereof for improved in vitro and in vivo antimicrobial photodynamic therapy and wound healing.Noha Nafee et al.International journal of pharmaceutics, 454(1), 249-258 (2013-07-10) Identifying the sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) as a potential target for hypericin--a theoretical study.Emma S E Eriksson et al.Physical chemistry chemical physics : PCCP, 14(36), 12637-12646 (2012-08-16) Hypericum perforatum: pharmacokinetic, mechanism of action, tolerability, and clinical drug-drug interactions.Emilio Russo et al.Phytotherapy research : PTR, 28(5), 643-655 (2013-07-31) Simultaneous determination of the predominant hyperforins and hypericins in St. John's Wort (Hypericum perforatum L.) by liquid chromatography.D E Gray et al.Journal of AOAC International, 83(4), 944-949 (2000-09-20) Spatiotemporal autophagic degradation of oxidatively damaged organelles after photodynamic stress is amplified by mitochondrial reactive oxygen species.Noemí Rubio et al.Autophagy, 8(9), 1312-1324 (2012-08-15) Probing the molecular mechanism of hypericin-induced parasite death provides insight into the role of spermidine beyond redox metabolism in Leishmania donovani.Shalini Singh et al.Antimicrobial agents and chemotherapy, 59(1), 15-24 (2014-10-15) Hypericin lights up the way for the potential treatment of nasopharyngeal cancer by photodynamic therapy.Malini Olivo et al.Current clinical pharmacology, 1(3), 217-222 (2008-08-01) Cellular mechanisms and prospective applications of hypericin in photodynamic therapy.Tobias Kiesslich et al.Current medicinal chemistry, 13(18), 2189-2204 (2006-08-22) Hypericin in cancer treatment: more light on the way.Patrizia Agostinis et al.The international journal of biochemistry & cell biology, 34(3), 221-241 (2002-02-19) In vitro fungicidal photodynamic effect of hypericin on Trichophyton spp.Manuel Pablo Paz-Cristobal et al.Mycopathologia, 178(3-4), 221-225 (2014-08-19) Inhibitors of translation targeting eukaryotic translation initiation factor 4A.Regina Cencic et al.Methods in enzymology, 511, 437-461 (2012-06-21) Antiviral activities of hypericin.J B Hudson et al.Antiviral research, 15(2), 101-112 (1991-02-01) The chemical and biological properties of hypericin--a compound with a broad spectrum of biological activities.G Lavie et al.Medicinal research reviews, 15(2), 111-119 (1995-03-01) The pro-apoptotic and anti-invasive effects of hypericin-mediated photodynamic therapy are enhanced by hyperforin or aristoforin in HT-29 colon adenocarcinoma cells.Martina Šemeláková et al.Journal of photochemistry and photobiology. B, Biology, 117, 115-125 (2012-10-27) Secondary metabolites of Hypericum leptophyllum Hochst., an endemic Turkish species.Necdet Camas et al.TheScientificWorldJournal, 2012, 501027-501027 (2012-06-01) Sequential systemic administrations of combretastatin A4 Phosphate and radioiodinated hypericin exert synergistic targeted theranostic effects with prolonged survival on SCID mice carrying bifocal tumor xenografts.Junjie Li et al.Theranostics, 3(2), 127-137 (2013-02-21) Photosensitizing effects of hypericin on head neck squamous cell carcinoma in vitro.Wiebke Laffers et al.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 272(3), 711-718 (2014-04-02) Necrosis avidity: a newly discovered feature of hypericin and its preclinical applications in necrosis imaging.Binghu Jiang et al.Theranostics, 3(9), 667-676 (2013-09-21)

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