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alpha-2 and imidazoline receptor agonists. Their pharmacology and therapeutic role.Z P Khan et al.Anaesthesia, 54(2), 146-165 (1999-04-24) Spontaneous withdrawal in intermittent morphine administration in rats and mice: effect of clonidine coadministration and sex-related differences.Oruc Allahverdiyev et al.Turkish journal of medical sciences, 45(6), 1380-1389 (2016-01-19) 'Seeing through a glass darkly': casting light on imidazoline 'I' sites.R M Eglen et al.Trends in pharmacological sciences, 19(9), 381-390 (1998-10-24) Restoration of Cingulate Long-Term Depression by Enhancing Non-apoptotic Caspase 3 Alleviates Peripheral Pain Hypersensitivity.Yong-Jie Wang et al.Cell reports, 33(6), 108369-108369 (2020-11-12) Safety and efficacy of clonidine and clonidine extended-release in the treatment of children and adolescents with attention deficit and hyperactivity disordersMing X, et al. Adolescent health, medicine and therapeutics, 2(2), 105-105 (2011) Clonidine hydrochloride--a safe and effective antihypertensive agent in pregnancy.Horvath JS, et al. Obstetrics and Gynecology, 66(5), 634-638 (1985) Bioceramic microneedles with flexible and self-swelling substrate.Bing Cai et al.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 94, 404-410 (2015-07-02) Effects of low-dose clonidine on cardiovascular and autonomic variables in adolescents with chronic fatigue: a randomized controlled trial.Even Fagermoen et al.BMC pediatrics, 15, 117-117 (2015-09-12) INT-005 Development and stability testing of oral clonidine hydrochloride solutions for use in neonatal patientsButtner B, et al. European Journal of Hospital Pharmacy (2017) Relationship between imidazoline and alpha2-adrenoceptors involved in the sympatho-inhibitory actions of centrally acting antihypertensive agents.G A Head et al.Journal of the autonomic nervous system, 72(2-3), 163-169 (1998-12-16) Clonidine for smoking cessationGourlay SG, et al. Cochrane database of systematic reviews (Online), 3, 105-105 (2004) Noradrenaline-mediated facilitation of inhibitory synaptic transmission in the dorsal horn of the rat spinal cord involves interlaminar communications.Frederik Seibt et al.The European journal of neuroscience, 42(9), 2654-2665 (2015-09-16) Activation of mesocorticolimbic reward circuits for assessment of relief of ongoing pain: a potential biomarker of efficacy.Jennifer Y Xie et al.Pain, 155(8), 1659-1666 (2014-05-28) Intra-articular morphine and clonidine produce comparable analgesia but the combination is not more effectiveGentili M, et al. British journal of anaesthesia, 79(5), 660-661 (1997) Effects of clonidine and methylphenidate on motor activity in Fmr1 knockout mice.Craige C Wrenn et al.Neuroscience letters, 585, 109-113 (2014-11-30) Evaluation of clonidine hydrochloride (Catapres): a new antihypertensive agentKosman ME JAMA : The Journal of the American Medical Association, 233(2), 174-176 (1975) Restoring spinal noradrenergic inhibitory tone attenuates pain hypersensitivity in a rat model of Parkinson?s diseaseCa Lei-Fang, et al. Neural Plast., 2016(5), e33710-e33710 (2016) Chemerin-induced arterial contraction is Gi-and calcium-dependentFerland DJ, et al. Vascular Pharmacology, 88, 30-41 (2017) Reinforcer magnitude and rate dependency: evaluation of resistance-to-change mechanisms.Jonathan W Pinkston et al.Behavioural pharmacology, 25(7), 629-636 (2014-08-15) Comparison of the effects of clonidine, loperamide and metoclopramide in two models of gastric emptying in the rat.Sonia Goineau et al.Fundamental & clinical pharmacology, 29(1), 86-94 (2014-06-13) Clonidine hydrochloride: Review of pharmacologic and clinical aspectsHouston MC Progress in Cardiovascular Diseases, 23(5), 337-350 (1981) Effects of indole-3-carbinol on clonidine-induced neurotoxicity in rats: Impact on oxidative stress, inflammation, apoptosis and monoamine levels.Reem N El-Naga et al.Neurotoxicology, 44, 48-57 (2014-06-01) Corneal Anesthesia With Site 1 Sodium Channel Blockers and Dexmedetomidine.James Brian McAlvin et al.Investigative ophthalmology & visual science, 56(6), 3820-3826 (2015-06-13) Discriminative stimulus effects of the novel imidazoline I₂ receptor ligand CR4056 in rats.Yanyan Qiu et al.Scientific reports, 4, 6605-6605 (2014-10-14) Adenylyl cyclases 5 and 6 underlie PIP3-dependent regulation.Gopireddy Raghavender Reddy et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(8), 3458-3471 (2015-05-02) Dual contributions of noradrenaline to behavioural flexibility and motivationJahn CI, et al. Psychopharmacology, 235(9), 2687-2702 (2018) Developing structure-activity relationships for the prediction of hepatotoxicity.Nigel Greene et al.Chemical research in toxicology, 23(7), 1215-1222 (2010-06-18) Clinical trial of clonidine hydrochloride as an antisecretory agent in choleraRabbani GH, et al. Gastroenterology, 97(2), 321-325 (1989) POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levelsCaron A, et al. eLife, 7(5), e33710-e33710 (2018) A predictive ligand-based Bayesian model for human drug-induced liver injury.Sean Ekins et al.Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2302-2308 (2010-09-17) Restoring spinal noradrenergic inhibitory tone attenuates pain hypersensitivity in a rat model of Parkinson?s diseaseCao LF, et al. Neural Plast., 2016(1), e0116766-e0116766 (2016) Monoamine receptor agonists, acting preferentially at presynaptic autoreceptors and heteroreceptors, downregulate the cell fate adaptor FADD in rat brain cortex.M Julia García-Fuster et al.Neuropharmacology, 89, 204-214 (2014-10-07) Chronic CRF1 receptor blockade reduces heroin intake escalation and dependence-induced hyperalgesia.Paula E Park et al.Addiction biology, 20(2), 275-284 (2013-12-18) Breathing and temperature control disrupted by morphine and stabilized by clonidine in neonatal rats.Kalpashri Kesavan et al.Respiratory physiology & neurobiology, 201, 93-100 (2014-07-11) Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.Pil H Lee et al.Bioorganic & medicinal chemistry letters, 20(1), 69-73 (2009-12-08) Chemical genetics reveals a complex functional ground state of neural stem cells.Phedias Diamandis et al.Nature chemical biology, 3(5), 268-273 (2007-04-10) Modeling nociception in zebrafish: a way forward for unbiased analgesic discovery.Andrew Curtright et al.PloS one, 10(1), e0116766-e0116766 (2015-01-15) Norepinephrine is required to promote wakefulness and for hypocretin-induced arousal in zebrafishSingh C, et al. eLife, 4(5), e07000-e07000 (2015)

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