熔点	262-263 ºC**
密度	1.209±0.06 g/cm3 (20 º

没有数据	没有数据

来源	SDS样本
没有数据	没有数据

产品合成路线

更多

名称	CAS号

更多

文章

同行评议文献

Colorimetric procedure for the microdetermination of the antibilharzial drug praziquantel and its applications to pharmaceutical formulationsAmin AS and Ahmed IS Microchimica Acta, 137(1-2), 35-40 (2001) PraziquantelCioli D and Pica-Mattoccia L Parasitology Research, 90(1), S3-S9 (2003) Efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin and praziquantel against experimental infections of Toxascaris leonina in cats.Martin Knaus et al.Veterinary parasitology, 202(1-2), 40-44 (2014-04-08) Intramedullary spinal neurocysticercosis treated successfully with medical therapy.Shameem Ahmed et al.Journal of the Egyptian Society of Parasitology, 44(3), 661-664 (2015-02-04) Efficacy of praziquantel and artemisinin derivatives for the treatment and prevention of human schistosomiasis: a systematic review and meta-analysis.Rong Liu et al.Parasites & vectors, 4, 201-201 (2011-10-19) Efficacy of combined antiparasitic therapy with praziquantel and albendazole for neurocysticercosis: a double-blind, randomised controlled trial.Hector H Garcia et al.The Lancet. Infectious diseases, 14(8), 687-695 (2014-07-08) Efficacy against nematode and cestode infections and safety of a novel topical fipronil, (S)-methoprene, eprinomectin and praziquantel combination product in domestic cats under field conditions in Europe.Steffen Rehbein et al.Veterinary parasitology, 202(1-2), 10-17 (2014-04-08) Development and validation of an HPLC-MS/MS method for simultaneous determination of ivermectin, febantel, praziquantel, pyrantel pamoate and related compounds in fixed dose combination for veterinary use.Pontes D L F, et al. Asian Journal of Pharmaceutical and Clinical Research, 6(2), 191-199 (2013) Efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin and praziquantel against adult and larval stages of Toxocara cati in cats.Martin Knaus et al.Veterinary parasitology, 202(1-2), 34-39 (2014-04-08) Susceptibility or resistance of praziquantel in human schistosomiasis: a review.Wei Wang et al.Parasitology research, 111(5), 1871-1877 (2012-10-12) [Study progress on the mode of action of praziquantel against schistosomes].Shu-Hua Xiao Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 25(6), 492-502 (2008-04-30) Post-treatment vascular leakage and inflammatory responses around brain cysts in porcine neurocysticercosis.Siddhartha Mahanty et al.PLoS neglected tropical diseases, 9(3), e0003577-e0003577 (2015-03-17) Simultaneous determination of albendazole and praziquantel by second derivative spectrophotometry and multivariated calibration methods in veterinary pharmaceutical formulationSoto C, et al. Analytical Sciences, 26(8), 891-896 (2010) Praziquantel, mefloquine-praziquantel, and mefloquine-artesunate-praziquantel against Schistosoma haematobium: a randomized, exploratory, open-label trial.Jennifer Keiser et al.PLoS neglected tropical diseases, 8(7), e2975-e2975 (2014-07-18) Ultrastructural analysis of β-lapachone-induced surface membrane damage in male adult Schistosoma mansoni BH strain worms.André de Lima Aires et al.Experimental parasitology, 142, 83-90 (2014-04-29) Can mass drug administration lead to the sustainable control of schistosomiasis?Allen G P Ross et al.The Journal of infectious diseases, 211(2), 283-289 (2014-07-30) Efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin, and praziquantel, against the ticks, Ixodes ricinus and Ixodes scapularis, on cats.E Tielemans et al.Veterinary parasitology, 202(1-2), 59-63 (2014-04-08) Efficacy of a single dose of a novel topical combination product containing eprinomectin to prevent heartworm infection in cats.Christine F Baker et al.Veterinary parasitology, 202(1-2), 49-53 (2014-04-08) Application of praziquantel in schistosomiasis japonica control strategies in China.Wei Wu et al.Parasitology research, 112(3), 909-915 (2013-01-30) Efficacy of a novel topical fipronil, (S)-methoprene, eprinomectin and praziquantel combination against naturally acquired intestinal nematode and cestode infections in cats.Martin Knaus et al.Veterinary parasitology, 202(1-2), 18-25 (2014-04-08) Closing the praziquantel treatment gap: new steps in epidemiological monitoring and control of schistosomiasis in African infants and preschool-aged children.J Russell Stothard et al.Parasitology, 138(12), 1593-1606 (2011-08-25) The hepatoprotective activity of blue green algae in Schistosoma mansoni infected mice.Azza H Mohamed et al.Experimental parasitology, 145, 7-13 (2014-07-13) [Progress of research on preparation and application of praziquantel].De-Zhi Wu et al.Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control, 25(2), 194-196 (2013-07-31) [Impact of host factors on the schistosome-killing process induced by praziquantel].Shu-Hua Xiao Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 26(3), 217-225 (2009-01-24) Direct determination of praziquantel in pharmaceutical formulations and human plasma by cathodic adsorptive stripping differential-pulse voltammetryGhoneim MM, et al. Journal of Pharmaceutical and Biomedical Analysis, 30(4), 1311-1318 (2002) Drugs for treating urinary schistosomiasis.Christine V Kramer et al.The Cochrane database of systematic reviews, 8(8), CD000053-CD000053 (2014-08-08) Ca2+ signalling, voltage-gated Ca2+ channels and praziquantel in flatworm neuromusculature.R M Greenberg Parasitology, 131 Suppl, S97-108 (2006-03-30) Efficacy in cats of a novel topical combination of fipronil, (S)-methoprene, eprinomectin, praziquantel, against induced infestations of Echinococcus multilocularis.Eric Tielemans et al.Veterinary parasitology, 202(1-2), 26-29 (2014-04-08) Pharmacokinetics and metabolism of eprinomectin in cats when administered in a novel topical combination of fipronil, (S)-methoprene, eprinomectin and praziquantel.Valerie Kvaternick et al.Veterinary parasitology, 202(1-2), 2-9 (2014-04-08) Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis.Michael J Doenhoff et al.Current opinion in infectious diseases, 21(6), 659-667 (2008-11-04) Posttreatment changes in cytokines induced by Schistosoma mansoni egg and worm antigens: dissociation of immunity- and morbidity-associated type 2 responses.Shona Wilson et al.The Journal of infectious diseases, 209(11), 1792-1800 (2013-12-21) Efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin and praziquantel against induced infections of Ancylostoma spp. nematodes of cats.Joseph B Prullage et al.Veterinary parasitology, 202(1-2), 30-33 (2014-04-08) Safety of the combined use of praziquantel and albendazole in the treatment of human hydatid disease.Lucía Alvela-Suárez et al.The American journal of tropical medicine and hygiene, 90(5), 819-822 (2014-03-13) Treatment of neurocysticercosis.The Lancet Infectious Diseases The Lancet. Infectious diseases, 14(8), 657-657 (2014-07-25) A rapid stability indicating LC-method for determination of praziquantel in presence of its pharmacopoeial impuritiesHashem H, et al. Arabian Journal of Chemistry, 10(2), S35-S41 (2017) Praziquantel: neglected drug? Ineffective treatment? Or therapeutic choice in cystic hydatid disease?J M Bygott et al.Acta tropica, 111(2), 95-101 (2009-04-21) Schistosomiasis control: praziquantel forever?Cioli D, et al. Molecular and Biochemical Parasitology, 195(1), 23-29 (2014) New insight into praziquantel against various developmental stages of schistosomes.Wei Wu et al.Parasitology research, 109(6), 1501-1507 (2011-10-11) A diagnostic challenge for Schistosomiasis japonica in China: consequences on praziquantel-based morbidity control.Yi-biao Zhou et al.Parasites & vectors, 4, 194-194 (2011-10-11) In vivo anthelmintic activity of Carex baccans and its active principle resveratrol against Hymenolepis diminuta.Bikash Ranjan Giri et al.Parasitology research, 114(2), 785-788 (2015-01-15) A short review of some pharmacological, therapeutic and toxicological properties of praziquantel in man and animals.Badreldin H Ali Pakistan journal of pharmaceutical sciences, 19(2), 170-175 (2006-06-06) Cimetidine synergizes with Praziquantel to enhance the immune response of HBV DNA vaccine via activating cytotoxic CD8(+) T cell.Xiaoping Xie et al.Human vaccines & immunotherapeutics, 10(6), 1688-1699 (2014-03-20) Is the full potential of the biopharmaceutics classification system reached?Christel A S Bergström et al.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 57, 224-231 (2013-10-01) Anthelmintic activity in vitro and in vivo of Baccharis trimera (Less) DC against immature and adult worms of Schistosoma mansoni.Rosimeire Nunes de Oliveira et al.Experimental parasitology, 139, 63-72 (2014-03-08) Efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin and praziquantel against adult and immature stages of the cat flea (Ctenocephalides felis) on cats.Christine Baker et al.Veterinary parasitology, 202(1-2), 54-58 (2014-04-08) Cerebral paragonimiasis: a retrospective analysis of 27 cases.Yong Xia et al.Journal of neurosurgery. Pediatrics, 15(1), 101-106 (2014-11-08) [Research progress of the evaluation methods on the resistance of schistosome to praziquantel].Jian Guo et al.Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 23(3), 182-184 (2005-11-23) Praziquantel and schistosomiasis.Alexander Dömling et al.ChemMedChem, 5(9), 1420-1434 (2010-08-03) Determining better treatments for neurocysticercosis.Gagandeep Singh et al.The Lancet. Infectious diseases, 14(8), 658-659 (2014-07-08) Utility of repeated praziquantel dosing in the treatment of schistosomiasis in high-risk communities in Africa: a systematic review.Charles H King et al.PLoS neglected tropical diseases, 5(9), e1321-e1321 (2011-09-29) Efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin and praziquantel against feline urinary bladder worm (Capillaria plica) infection.Martin Knaus et al.Veterinary parasitology, 202(1-2), 45-48 (2014-04-08) Voltage-gated calcium channel subunits from platyhelminths: potential role in praziquantel action.Michael C Jeziorski et al.International journal for parasitology, 36(6), 625-632 (2006-03-21) Suppression of basophil histamine release and other IgE-dependent responses in childhood Schistosoma mansoni/hookworm coinfection.Angela Pinot de Moira et al.The Journal of infectious diseases, 210(8), 1198-1206 (2014-05-02) [Research progress on the action of praziquantel on voltage-gated Ca2+ channel in schistosomes].Ling Zhang et al.Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 26(1), 58-62 (2008-07-22) Efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin and praziquantel against larval and adult stages of the cat lungworm, Aelurostrongylus abstrusus.Martin Knaus et al.Veterinary parasitology, 202(1-2), 64-68 (2014-04-08) Dosing of praziquantel by height in sub-Saharan African adults.Chiquita A Palha De Sousa et al.The American journal of tropical medicine and hygiene, 90(4), 634-637 (2014-03-05) Metabolic profiling of praziquantel enantiomers.Haina Wang et al.Biochemical pharmacology, 90(2), 166-178 (2014-05-14) Praziquantel: its use in control of schistosomiasis in sub-Saharan Africa and current research needs.M J Doenhoff et al.Parasitology, 136(13), 1825-1835 (2009-03-14) Praziquantel for the treatment of schistosomiasis: its use for control in areas with endemic disease and prospects for drug resistance.Michael J Doenhoff et al.Expert review of anti-infective therapy, 4(2), 199-210 (2006-04-07)

备注