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Total Synthesis of Enantiopure Phalarine via a Stereospecific Pictet? Spengler Reaction: Traceless Transfer of Chirality from l-Tryptophan.Trzupek J D, et al. Journal of the American Chemical Society, 132(24), 8506-8512 (2010) G. Kinast et al.Angewandte Chemie (International Edition in English), 88, 261-261 (1976) otal Synthesis of Phalarine.Li C, et al. Angewandte Chemie (International Edition in English), 46(9), 1448-1450 (2007) The Mannich reaction-II: derivatization of aldehydes and ketones using dimethyl (methylene) ammonium salts.Holy N, et al. Tetrahedron, 35(5), 613-619 (1979) H.-U. Reissig et al.Liebigs Ann. Chem., 1914-1914 (1986) A versatile synthesis of 3-substituted 4-cyano-1, 2, 3, 4-tetrahydro-1-oxo-β-carbolines.Huber K, et al. Synthesis, 2010(22), 3849-3854 (2010) H. Bohme Angewandte Chemie (International Edition in English), 88, 772-772 (1976) N. Holy et al. Tetrahedron, 35, 613-613 (1979) Design and synthesis of novel N-hydroxy-dihydronaphthyridinones as potent and orally bioavailable HIV-1 integrase inhibitors.Johnson T W, et al. Journal of Medicinal Chemistry, 54(9), 3393-3417 (2011) Arylpyrrolizines as inhibitors of microsomal prostaglandin E2 synthase-1 (mPGES-1) or as dual inhibitors of mPGES-1 and 5-lipoxygenase (5-LOX).Liedtke A J, et al. Journal of Medicinal Chemistry, 52(15), 4968-4972 (2009)

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