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Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A1 enzymes.Nobumitsu Hanioka et al.Life sciences, 87(7-8), 261-268 (2010-07-14) Pharmacokinetics and metabolism of AMG 232, a novel orally bioavailable inhibitor of the MDM2-p53 interaction, in rats, dogs and monkeys: in vitro-in vivo correlation.Qiuping Ye et al.Xenobiotica; the fate of foreign compounds in biological systems, 45(8), 681-692 (2015-03-24) Generation and validation of rapid computational filters for cyp2d6 and cyp3a4.Sean Ekins et al.Drug metabolism and disposition: the biological fate of chemicals, 31(9), 1077-1080 (2003-08-16) Examination of purported probes of human CYP2B6.S Ekins et al.Pharmacogenetics, 7(3), 165-179 (1997-06-01) Functional characterization of wild-type and variant (T202I and M59I) human UDP-glucuronosyltransferase 1A10.Hideto Jinno et al.Drug metabolism and disposition: the biological fate of chemicals, 31(5), 528-532 (2003-04-16) Piceatannol exhibits potential food-drug interactions through the inhibition of human UDP-glucuronosyltransferase (UGT) in Vitro.Lili Jiang et al.Toxicology in vitro : an international journal published in association with BIBRA, 67, 104890-104890 (2020-05-25) Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of posaconazole (Noxafil).Anima Ghosal et al.Drug metabolism and disposition: the biological fate of chemicals, 32(2), 267-271 (2004-01-28) Functional expression and comparative characterization of four feline P450 cytochromes using fluorescent substrates.Gaku Okamatsu et al.Xenobiotica; the fate of foreign compounds in biological systems, 47(11), 951-961 (2016-11-15) Effects of plant-derived phenols on rat liver cytochrome P450 2B1 activity.H T Huynh et al.Anticancer research, 22(3), 1699-1703 (2002-08-10) Nitric oxide-regulated proteolysis of human CYP2B6 via the ubiquitin-proteasome system.Choon-Myung Lee et al.Free radical biology & medicine, 108, 478-486 (2017-04-22) Identification of UGT2B9*2 and UGT2B33 isolated from female rhesus monkey liver.Brian Dean et al.Archives of biochemistry and biophysics, 426(1), 55-62 (2004-05-08) HepG2 cells as an in vitro model for evaluation of cytochrome P450 induction by xenobiotics.Jong Min Choi et al.Archives of pharmacal research, 38(5), 691-704 (2014-10-23) BFCOD activity in fish cell lines and zebrafish embryos and its modulation by chemical ligands of human aryl hydrocarbon and nuclear receptors.N Creusot et al.Environmental science and pollution research international, 22(21), 16393-16404 (2014-12-05) Roles of Residues F206 and V367 in Human CYP2B6: Effects of Mutations on Androgen Hydroxylation, Mechanism-Based Inactivation, and Reversible Inhibition.Hsia-Lien Lin et al.Drug metabolism and disposition: the biological fate of chemicals, 44(11), 1771-1779 (2016-08-20) Base-induced phototautomerization in 7-hydroxy-4-(trifluoromethyl) coumarinWestlake BC, et al. The Journal of Physical Chemistry B, 116(51), 14886-14891 (2012) Induction via Functional Protein Stabilization of Hepatic Cytochromes P450 upon gp78/Autocrine Motility Factor Receptor (AMFR) Ubiquitin E3-Ligase Genetic Ablation in Mice: Therapeutic and Toxicological Relevance.Doyoung Kwon et al.Molecular pharmacology, 96(5), 641-654 (2019-09-08) Influence of diet supplementation with green tea extract on drug-metabolizing enzymes in a mouse model of monosodium glutamate-induced obesity.Iva Boušová et al.European journal of nutrition, 55(1), 361-371 (2015-02-11) Risto O Juvonen et al.Xenobiotica; the fate of foreign compounds in biological systems, 50(8), 885-893 (2020-01-07)Sulfonation is an important high affinity elimination pathway for phenolic compounds.In this study sulfonation of 7-hydroxycoumarin and 13 its derivatives were evaluated in liver cytosols of human and six animal species. 7-hydroxycoumarin and its derivatives are strongly fluorescent, and their... 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Direct fluorescence monitoring of the deethylation of 7-ethoxy-4-trifluoromethylcoumarin.J T Buters et al.Biochemical pharmacology, 46(9), 1577-1584 (1993-11-02) Development of new Coumarin-based profluorescent substrates for human cytochrome P450 enzymes.Risto O Juvonen et al.Xenobiotica; the fate of foreign compounds in biological systems, 49(9), 1015-1024 (2018-10-03) In Vitro Metabolic Transformation of Pharmaceuticals by Hepatic S9 Fractions from Common Carp (Cyprinus carpio).Viktoriia Burkina et al.Molecules (Basel, Switzerland), 25(11) (2020-06-14) Environmentally persistent free radical-containing particulate matter competitively inhibits metabolism by cytochrome P450 1A2.James R Reed et al.Toxicology and applied pharmacology, 289(2), 223-230 (2015-10-02) Coumarins as novel 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for potential treatment of prostate cancer.Koichiro Harada et al.Bioorganic & medicinal chemistry letters, 20(1), 272-275 (2009-12-04)

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