熔点	60-63 ºC
沸点	89-92 ºC (2 mmHg)

危险品标志	Xn
危险类别码	R22;R36/37/38
安全说明书	S26;S36/37/39

来源	SDS样本
Alfa-Aesar	浏览或下载
Sigma-Aldrich	浏览或下载
TCI	浏览或下载

产品合成路线

更多

名称	CAS号

更多

文章

同行评议文献

Ardisiphenol D, a resorcinol derivative identified from Ardisia brevicaulis, exerts antitumor effect through inducing apoptosis in human non-small-cell lung cancer A549 cells.Feng Zhao et al.Pharmaceutical biology, 52(7), 797-803 (2014-01-08) Application of immobilized ATP to the study of NLRP inflammasomes.Kuo-Chieh Liao et al.Archives of biochemistry and biophysics, 670, 104-115 (2019-01-15) Targeting the PD-L1/DNMT1 axis in acquired resistance to sorafenib in human hepatocellular carcinoma.Jianhua Liu et al.Oncology reports, 38(2), 899-907 (2017-06-20) Regulating effect of baicalin on IKK/IKB/NF-kB signaling pathway and apoptosis-related proteins in rats with ulcerative colitis.Jian Shen et al.International immunopharmacology, 73, 193-200 (2019-05-20) Tumor cells educate mesenchymal stromal cells to release chemoprotective and immunomodulatory factors.Augustin Le Naour et al.Journal of molecular cell biology, 12(3), 202-215 (2019-09-11) Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation.Hiroyuki Nagashima et al.Immunity, 51(4), 682-695 (2019-07-30) CD5 dynamically calibrates basal NF-κB signaling in T cells during thymic development and peripheral activation.Courtney A Matson et al.Proceedings of the National Academy of Sciences of the United States of America, 117(25), 14342-14353 (2020-06-10) Nuclear factor-κB p65 regulates glutaminase 1 expression in human hepatocellular carcinoma.Meng Dong et al.OncoTargets and therapy, 11, 3721-3729 (2018-07-11) Inhibition of STAT5a by Naa10p contributes to decreased breast cancer metastasis.Yan Zeng et al.Carcinogenesis, 35(10), 2244-2253 (2014-06-14) Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.Qiang Mao et al.Parasitology research, 114(2), 659-670 (2014-11-22) Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation.Stephen Zewinger et al.Nature immunology, 21(1), 30-41 (2019-12-11) Inhibitory Effect of Hesperidin on the Expression of Programmed Death Ligand (PD-L1) in Breast Cancer.Prachya Kongtawelert et al.Molecules (Basel, Switzerland), 25(2) (2020-01-16) Differential regulation by IFN‑γ on TNF‑α‑induced chemokine expression in synovial fibroblasts from temporomandibular joint.Kouji Ohta et al.Molecular medicine reports, 16(5), 6850-6857 (2017-09-14) Epstein-Barr Virus Latent Membrane Protein-1 Induces the Expression of SUMO-1 and SUMO-2/3 in LMP1-positive Lymphomas and Cells.Sadia Salahuddin et al.Scientific reports, 9(1), 208-208 (2019-01-20) Butyrate alleviates inflammatory response and NF-κB activation in human degenerated intervertebral disc tissues.Jialin Jia et al.International immunopharmacology, 78, 106004-106004 (2019-11-30) Heme Oxygenase-1 Inhibits HLA Class I Antibody-Dependent Endothelial Cell Activation.Eva Zilian et al.PloS one, 10(12), e0145306-e0145306 (2015-12-23) Reactive oxygen species induce Cox-2 expression via TAK1 activation in synovial fibroblast cells.Yuta Onodera et al.FEBS open bio, 5, 492-501 (2015-06-26) Curcumin promotes the oncoltyic capacity of vesicular stomatitis virus for the treatment of prostate cancers.Dylan J Fehl et al.Virus research, 228, 14-23 (2016-11-21) Nanospheres Loaded with Curcumin Improve the Bioactivity of Umbilical Cord Blood-Mesenchymal Stem Cells via c-Src Activation During the Skin Wound Healing Process.Do-Wan Kim et al.Cells, 9(6) (2020-06-19) Human Invariant NKT Cells Induce IL-1β Secretion by Peripheral Blood Monocytes via a P2X7-Independent Pathway.Laura E Felley et al.Journal of immunology (Baltimore, Md. : 1950), 197(6), 2455-2464 (2016-08-19) TRIB3 mediates the expression of Wnt5a and activation of nuclear factor-κB in Porphyromonas endodontalis lipopolysaccharide-treated osteoblasts.Y Yu et al.Molecular oral microbiology, 30(4), 295-306 (2015-01-21) Repurposing of clinically approved drugs for treatment of coronavirus disease 2019 in a 2019-novel coronavirus-related coronavirus model.Hua-Hao Fan et al.Chinese medical journal, 133(9), 1051-1056 (2020-03-10) HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS production.Rawan El-Amine et al.Redox biology, 15, 97-108 (2017-12-09) Blastocystis ratti contains cysteine proteases that mediate interleukin-8 response from human intestinal epithelial cells in an NF-kappaB-dependent manner.Manoj K Puthia et al.Eukaryotic cell, 7(3), 435-443 (2007-12-25) Quercetin Inhibits the Production of IL-1β-Induced Inflammatory Cytokines and Chemokines in ARPE-19 Cells via the MAPK and NF-κB Signaling Pathways.Shu-Chen Cheng et al.International journal of molecular sciences, 20(12) (2019-06-20) P120-catenin regulates pulmonary fibrosis and TGF-β induced lung fibroblast differentiation.Yang Zhang et al.Life sciences, 230, 35-44 (2019-05-28) Mevastatin-Induced AP-1-Dependent HO-1 Expression Suppresses Vascular Cell Adhesion Molecule-1 Expression and Monocyte Adhesion on Human Pulmonary Alveolar Epithelial Cells Challenged with TNF-α.Chuen-Mao Yang et al.Biomolecules, 10(3) (2020-03-04) Baicalin attenuates fibrogenic process in human renal proximal tubular cells (HK-2) exposed to diabetic milieu.Jung Eun Nam et al.Life sciences, 254, 117742-117742 (2020-05-04) Extracellular TDP-43 aggregates target MAPK/MAK/MRK overlapping kinase (MOK) and trigger caspase-3/IL-18 signaling in microglia.María M Leal-Lasarte et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31(7), 2797-2816 (2017-03-25) Vitamin D-Binding Protein Enhances Epithelial Ovarian Cancer Progression by Regulating the Insulin-like Growth Factor-1/Akt Pathway and Vitamin D Receptor Transcription.Yu-Fang Huang et al.Clinical cancer research : an official journal of the American Association for Cancer Research, 24(13), 3217-3228 (2018-02-25) TLR3/TRIF signalling pathway regulates IL-32 and IFN-β secretion through activation of RIP-1 and TRAF in the human cornea.Ga Bin Park et al.Journal of cellular and molecular medicine, 19(5), 1042-1054 (2015-03-11) Lipopolysaccharide-induced α-catenin downregulation enhances the motility of human colorectal cancer cells in an NF-κB signaling-dependent manner.Guoping Cheng et al.OncoTargets and therapy, 9, 7563-7571 (2016-12-23) Hypoxia inducible factor-1 promotes liver fibrosis in nonalcoholic fatty liver disease by activating PTEN/p65 signaling pathway.Jie Han et al.Journal of cellular biochemistry, 120(9), 14735-14744 (2019-04-23) MKP-1 negative regulates Staphylococcus aureus induced inflammatory responses in Raw264.7 cells: roles of PKA-MKP-1 pathway and enhanced by rolipram.Yiqing Pan et al.Scientific reports, 7(1), 12366-12366 (2017-09-30) α7 nicotinic acetylcholine receptor in tumor-associated macrophages inhibits colorectal cancer metastasis through the JAK2/STAT3 signaling pathway.Rushan Fei et al.Oncology reports, 38(5), 2619-2628 (2017-09-14) Synergistic protective effect of paeoniflorin and β-ecdysterone against rotenone-induced neurotoxicity in PC12 cells.Han Liu et al.Apoptosis : an international journal on programmed cell death, 21(12), 1354-1365 (2016-10-28) IL-6/IL-6R pathway is a therapeutic target in chemoresistant ovarian cancer.Hassan Yousefi et al.Tumori, 105(1), 84-91 (2018-07-20) HIV-1 Tat - TLR4/MD2 interaction drives the expression of IDO-1 in monocytes derived dendritic cells through NF-κB dependent pathway.Elmostafa Bahraoui et al.Scientific reports, 10(1), 8177-8177 (2020-05-20) Microglia amplify inflammatory activation of astrocytes in manganese neurotoxicity.Kelly S Kirkley et al.Journal of neuroinflammation, 14(1), 99-99 (2017-05-10) Dual blockade of protease-activated receptor 1 and 2 additively ameliorates diabetic kidney disease.Shohei Mitsui et al.American journal of physiology. Renal physiology, 318(5), F1067-F1073 (2020-03-24) Intestinal epithelial cell apoptosis due to a hemolytic toxin from Vibrio vulnificus and protection by a 36 kDa glycoprotein from Rhus verniciflua Stokes.Young-Min Lee et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 125, 46-54 (2018-12-29) Role of CXCR1 and Interleukin-8 in Methamphetamine-Induced Neuronal Apoptosis.Si-Hao Du et al.Frontiers in cellular neuroscience, 12, 230-230 (2018-08-21) vFLIP upregulates IKKε, leading to spindle morphology formation through RelA activation.Zunlin Yang et al.Virology, 522, 106-121 (2018-07-22) MicroRNA-132 and microRNA-212 mediate doxorubicin resistance by down-regulating the PTEN-AKT/NF-κB signaling pathway in breast cancer.Manxin Xie et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 102, 286-294 (2018-03-24) C-reactive protein exacerbates epithelial-mesenchymal transition through Wnt/β-catenin and ERK signaling in streptozocin-induced diabetic nephropathy.Lin Zhang et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(5), 6551-6563 (2019-02-23) The Mechanism of Bisphenol A Atherogenicity Involves Apolipoprotein A-I Downregulation through NF-κB Activation.Violeta G Trusca et al.International journal of molecular sciences, 20(24) (2019-12-18) Metformin ameliorates animal models of dermatitis.Soo Young Choi et al.Inflammopharmacology, 28(5), 1293-1300 (2020-04-30) LncRNA HOXA-AS2 represses endothelium inflammation by regulating the activity of NF-κB signaling.Xinxing Zhu et al.Atherosclerosis, 281, 38-46 (2019-01-19) IL-33/ST2 axis promotes glioblastoma cell invasion by accumulating tenascin-C.Jian-Fei Zhang et al.Scientific reports, 9(1), 20276-20276 (2020-01-01) Regulation of Human Platelet Activation and Prevention of Arterial Thrombosis in Mice by Auraptene through Inhibition of NF-κB Pathway.Chih-Wei Hsia et al.International journal of molecular sciences, 21(13) (2020-07-11) Role of TNFα and leptin signaling in colon cancer incidence and tumor growth under obese phenotype.Snahlata Singh et al.Biochimica et biophysica acta. Molecular basis of disease, 1866(5), 165660-165660 (2020-01-01) Oct4 suppresses IR‑induced premature senescence in breast cancer cells through STAT3- and NF‑κB-mediated IL‑24 production.Jeong-Yub Kim et al.International journal of oncology, 53(1), 47-58 (2018-05-12) Distribution of positively charged amino acid residues in antimicrobial peptide epinecidin-1 is crucial for in vitro glioblastoma cytotoxicity and its underlying mechanisms.Bor-Chyuan Su et al.Chemico-biological interactions, 315, 108904-108904 (2019-11-24) Berberine ameliorates lipopolysaccharide‑induced inflammatory responses in mouse inner medullary collecting duct‑3 cells by downregulation of NF‑κB pathway.Dong-Gu Kim et al.Molecular medicine reports, 21(1), 258-266 (2019-11-21) Anti-inflammatory property of quercetin through downregulation of ICAM-1 and MMP-9 in TNF-α-activated retinal pigment epithelial cells.Shu-Chen Cheng et al.Cytokine, 116, 48-60 (2019-01-28) Excessive periostin expression and Th2 response in patients with nasal polyps: association with asthma.Yi Wei et al.Journal of thoracic disease, 10(12), 6585-6597 (2019-02-13) Aloe-emodin from rhubarb (Rheum rhabarbarum) inhibits lipopolysaccharide-induced inflammatory responses in RAW264.7 macrophages.Boyang Hu et al.Journal of ethnopharmacology, 153(3), 846-853 (2014-04-02) Fusion and hemagglutinin proteins of canine distemper virus promote osteoclast formation through NF-κB dependent and independent mechanisms.Wei Wang et al.Experimental cell research, 378(2), 171-181 (2019-03-19) Salinomycin promotes T-cell proliferation by inhibiting the expression and enzymatic activity of immunosuppressive indoleamine-2,3-dioxygenase in human breast cancer cells.Azubuike Peter Ebokaiwe et al.Toxicology and applied pharmacology, 404, 115203-115203 (2020-08-22) Galectin-8 induces functional disease markers in human osteoarthritis and cooperates with galectins-1 and -3.Daniela Weinmann et al.Cellular and molecular life sciences : CMLS (2018-06-24) Suppression of CYP1 members of the AHR response by pathogen-associated molecular patterns.Adam G Peres et al.Journal of leukocyte biology, 102(6), 1471-1480 (2017-10-12) Ginsenoside Rh2 Ameliorates Doxorubicin-Induced Senescence Bystander Effect in Breast Carcinoma Cell MDA-MB-231 and Normal Epithelial Cell MCF-10A.Jin-Gang Hou et al.International journal of molecular sciences, 20(5) (2019-03-16) hTERT mediates norepinephrine-induced Slug expression and ovarian cancer aggressiveness.M J Choi et al.Oncogene, 34(26), 3402-3412 (2014-08-26) Transforming growth factor-β inhibits IQ motif containing guanosine triphosphatase activating protein 1 expression in lung fibroblasts via the nuclear factor-κB signaling pathway.Chuanyue Zong et al.Molecular medicine reports, 12(1), 442-448 (2015-02-17) Betamethasone suppresses the inflammatory response in LPS-stimulated dental pulp cells through inhibition of NF-κB.Dan Wang et al.Archives of oral biology, 98, 156-163 (2018-12-01) L-carnosine induces apoptosis/cell cycle arrest via suppression of NF-κB/STAT1 pathway in HCT116 colorectal cancer cells.Jooyeon Lee et al.In vitro cellular & developmental biology. Animal, 54(7), 505-512 (2018-06-06) Ethanolic extract of leaf of Dillenia pentagyna reduces in-vitro cell migration and induces intrinsic pathway of apoptosis via downregulation of NF-κβ in human NSCLC A549 cells.Debapriya De et al.Journal of cellular biochemistry, 120(12), 19841-19857 (2019-07-19) Inhibition of programmed death ligand 1 (PD-L1) expression in breast cancer cells by sesamin.Prachya Kongtawelert et al.International immunopharmacology, 86, 106759-106759 (2020-07-15) Transcription Factor Runx3 Is Induced by Influenza A Virus and Double-Strand RNA and Mediates Airway Epithelial Cell Apoptosis.Huachen Gan et al.Scientific reports, 5, 17916-17916 (2015-12-09) Bay 11-7082 inhibits transcription factor NF-kappaB and induces apoptosis of HTLV-I-infected T-cell lines and primary adult T-cell leukemia cellsMori N, et al. Blood, 100(5), 1828-1834 (2002) Hypoxia-induced RelA/p65 derepresses SLC16A3 (MCT4) by downregulating ZBTB7A.Seo-Hyun Choi et al.Biochimica et biophysica acta. Gene regulatory mechanisms, 1862(8), 771-785 (2019-07-05) Uric acid promotes chemokine and adhesion molecule production in vascular endothelium via nuclear factor-kappa B signaling.W Y Liang et al.Nutrition, metabolism, and cardiovascular diseases : NMCD, 25(2), 187-194 (2014-10-16) Interleukin 37 Suppresses M1 Macrophage Polarization Through Inhibition of the Notch1 and Nuclear Factor Kappa B Pathways.Peitao Zhou et al.Frontiers in cell and developmental biology, 8, 56-56 (2020-03-03) Lactobacillus acidophilus suppresses intestinal inflammation by inhibiting endoplasmic reticulum stress.Da Hye Kim et al.Journal of gastroenterology and hepatology, 34(1), 178-185 (2018-06-23) Picroside II Isolated from Pseudolysimachion rotundum var. subintegrum Inhibits Glucocorticoid Refractory Serum Amyloid A (SAA) Expression and SAA-induced IL-33 Secretion.Kiram Lee et al.Molecules (Basel, Switzerland), 24(10) (2019-05-30) Inhibition of IL-1β by Aliskiren Improved Renal AQP2 Expression and Urinary Concentration Defect in Ureteral Obstruction and Release.Shan Hu et al.Frontiers in physiology, 10, 1157-1157 (2019-10-02) The Immunosuppressive Microenvironment in BRCA1-IRIS-Overexpressing TNBC Tumors Is Induced by Bidirectional Interaction with Tumor-Associated Macrophages.Eman Sami et al.Cancer research, 80(5), 1102-1117 (2020-01-09) Inhibition of Interleukin 10 Transcription through the SMAD2/3 Signaling Pathway by Ca2+-Activated K+ Channel KCa3.1 Activation in Human T-Cell Lymphoma HuT-78 Cells.Miki Matsui et al.Molecular pharmacology, 95(3), 294-302 (2019-01-10) Clonorchis sinensis excretory-secretory products regulate migration and invasion in cholangiocarcinoma cells via extracellular signal-regulated kinase 1/2/nuclear factor-κB-dependent matrix metalloproteinase-9 expression.Jhang Ho Pak et al.International journal for parasitology, 47(1), 51-59 (2016-12-07) Ah-Ra Jang et al.Immune network, 19(2), e13-e13 (2019-05-16)6-kDa early secretory antigenic target (ESAT6), a virulent factor of Mycobacterium tuberculosis, is involved in immune regulation. However, the underlying mechanism behind the activation and maturation of dendritic cells (DCs) by ESAT6 remains unclear. In this study, we investigated the... The inflammatory cytokine TNF-α regulates the biological behavior of rat nucleus pulposus mesenchymal stem cells through the NF-κB signaling pathway in vitro.Shi Cheng et al.Journal of cellular biochemistry, 120(8), 13664-13679 (2019-04-03) Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasomeJuliana C, et al. The Journal of Biological Chemistry, 285(13), 9792-9802 (2010) MicroRNA-503-5p Inhibits the CD97-Mediated JAK2/STAT3 Pathway in Metastatic or Paclitaxel-Resistant Ovarian Cancer Cells.Ga Bin Park et al.Neoplasia (New York, N.Y.), 21(2), 206-215 (2019-01-10) Upregulation of IL-6 is involved in moderate hyperthermia induced proliferation and invasion of hepatocellular carcinoma cells.Xu-Hua Duan et al.European journal of pharmacology, 833, 230-236 (2018-06-13) HSP27 regulates TGF-β mediated lung fibroblast differentiation through the Smad3 and ERK pathways.Gang Wang et al.International journal of molecular medicine, 39(1), 183-190 (2016-12-03) Adhesion to stromal cells mediates imatinib resistance in chronic myeloid leukemia through ERK and BMP signaling pathways.Atul Kumar et al.Scientific reports, 7(1), 9535-9535 (2017-08-27) Critical role of TRIF and MyD88 in Mycobacterium tuberculosis Hsp70-mediated activation of dendritic cells.Tae-Hyoun Kim et al.Cytokine, 71(2), 139-144 (2014-12-03) Heme oxygenase-1 dysregulates macrophage polarization and the immune response to Helicobacter pylori.Alain P Gobert et al.Journal of immunology (Baltimore, Md. : 1950), 193(6), 3013-3022 (2014-08-12) miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity.Bo Li et al.The Journal of clinical investigation, 127(10), 3702-3716 (2017-09-06) Effect of threonine on secretory immune system using a chicken intestinal ex vivo model with lipopolysaccharide challenge.Q Zhang et al.Poultry science, 96(9), 3043-3051 (2017-04-22) Rgnef promotes ovarian tumor progression and confers protection from oxidative stress.Elizabeth G Kleinschmidt et al.Oncogene, 38(36), 6323-6337 (2019-07-17) Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.Curtis D Hodge et al.ACS chemical biology, 10(7), 1718-1728 (2015-04-25) Increased antigen presentation but impaired T cells priming after upregulation of interferon-beta induced by lipopolysaccharides is mediated by upregulation of B7H1 and GITRL.Fang Wang et al.PloS one, 9(8), e105636-e105636 (2014-08-22) D‑galactose induces astrocytic aging and contributes to astrocytoma progression and chemoresistance via cellular senescence.Jingang Hou et al.Molecular medicine reports, 20(5), 4111-4118 (2019-09-24) Immunosuppressive Siglec-E ligands on mouse aorta are up-regulated by LPS via NF-κB pathway.Hongmei Liu et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 122, 109760-109760 (2020-01-10) Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression.Li Yu et al.Nature communications, 11(1), 2286-2286 (2020-05-10) Stimulation of dendritic cell functional maturation by capsid protein from chikungunya virus.Vu Xuan Nghia et al.Iranian journal of basic medical sciences, 23(10), 1268-1274 (2020-11-06) Phytoglycoprotein isolated from Dioscorea batatas Decne promotes intestinal epithelial wound healing.Ji-Yun Kim et al.Chinese journal of natural medicines, 18(10), 738-748 (2020-10-12) Heme oxygenase-1 dysregulates macrophage polarization and the immune response to Helicobacter pylori.Alain P Gobert et al.Journal of immunology (Baltimore, Md. : 1950), 193(6), 3013-3022 (2014-08-12) Critical role of TRIF and MyD88 in Mycobacterium tuberculosis Hsp70-mediated activation of dendritic cells.Tae-Hyoun Kim et al.Cytokine, 71(2), 139-144 (2014-12-03) Effect of threonine on secretory immune system using a chicken intestinal ex vivo model with lipopolysaccharide challenge.Q Zhang et al.Poultry science, 96(9), 3043-3051 (2017-04-22) LncRNA NKILA regulates endothelium inflammation by controlling a NF-κB/KLF4 positive feedback loop.Xinxing Zhu et al.Journal of molecular and cellular cardiology, 126, 60-69 (2018-11-13) miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity.Bo Li et al.The Journal of clinical investigation, 127(10), 3702-3716 (2017-09-06) Characterization of p38 MAPK isoforms for drug resistance study using systems biology approach.Huiming Peng et al.Bioinformatics (Oxford, England), 30(13), 1899-1907 (2014-03-13) PRDX2 protects against oxidative stress induced by H. pylori and promotes resistance to cisplatin in gastric cancer.Sen Wang et al.Redox biology, 28, 101319-101319 (2019-09-20) Alpha-lipoic acid attenuates p-cresyl sulfate-induced renal tubular injury through suppression of apoptosis and autophagy in human proximal tubular epithelial cells.Jung Sun Park et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 112, 108679-108679 (2019-02-25) NF-κB inhibitor with Temozolomide results in significant apoptosis in glioblastoma via the NF-κB(p65) and actin cytoskeleton regulatory pathways.Naze G Avci et al.Scientific reports, 10(1), 13352-13352 (2020-08-10) miR-191 suppresses angiogenesis by activation of NF-κB signaling.Yuan Gu et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31(8), 3321-3333 (2017-04-21) Cycling hypoxia induces chemoresistance through the activation of reactive oxygen species-mediated B-cell lymphoma extra-long pathway in glioblastoma multiforme.Wei-Ling Chen et al.Journal of translational medicine, 13, 389-389 (2015-12-30) Yu Ping Feng San, an ancient Chinese herbal decoction, regulates the expression of inducible nitric oxide synthase and cyclooxygenase-2 and the activity of intestinal alkaline phosphatase in cultures.Crystal Y Q Du et al.PloS one, 9(6), e100382-e100382 (2014-06-27) The regulation of NDRG2 expression during ATLL development after HTLV-1 infection.Tomonaga Ichikawa et al.Biochimica et biophysica acta. Molecular basis of disease, 1865(10), 2633-2646 (2019-07-12) Atorvastatin reduces long pentraxin 3 expression in vascular cells by inhibiting protein geranylgeranylation.Roberta Baetta et al.Vascular pharmacology, 67-69, 38-47 (2015-04-08) NFkB is essential for activin-induced colorectal cancer migration via upregulation of PI3K-MDM2 pathway.Arundhati Jana et al.Oncotarget, 8(23), 37377-37393 (2017-04-19) TREM-1-accentuated lung injury via miR-155 is inhibited by LP17 nanomedicine.Zhihong Yuan et al.American journal of physiology. Lung cellular and molecular physiology, 310(5), L426-L438 (2015-12-20) Identification of EGF-NF-κB-FOXC1 signaling axis in basal-like breast cancer.Stacey Chung et al.Cell communication and signaling : CCS, 15(1), 22-22 (2017-06-21) PPARβ/δ directs the therapeutic potential of mesenchymal stem cells in arthritis.P Luz-Crawford et al.Annals of the rheumatic diseases, 75(12), 2166-2174 (2016-03-11) The E3 ubiquitin ligase RNF114 and TAB1 degradation are required for maternal-to-zygotic transition.Ye Yang et al.EMBO reports, 18(2), 205-216 (2017-01-12) Clinical and functional significance of STEAP4-splice variant in CD14H Ebe et al.Clinical and experimental immunology, 191(3), 338-348 (2017-10-29) Protective mechanisms of resveratrol derivatives against TNF-α-induced inflammatory responses in rat mesangial cells.I-Ta Lee et al.Cytokine, 113, 380-392 (2018-11-06) RANK Ligand Helps Immunity to Leishmania major by Skewing M2-Like Into M1 Macrophages.Thaís S Rigoni et al.Frontiers in immunology, 11, 886-886 (2020-06-02) Nonsaponin fraction of Korean Red Ginseng attenuates cytokine production via inhibition of TLR4 expression.Huijeong Ahn et al.Journal of ginseng research, 43(2), 291-299 (2019-04-13) Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease.Lisa Mayr et al.Nature communications, 11(1), 1775-1775 (2020-04-15) The heparanase inhibitor PG545 is a potent anti-lymphoma drug: Mode of action.Marina Weissmann et al.Matrix biology : journal of the International Society for Matrix Biology, 77, 58-72 (2018-08-11) Standardised comparison of limonene-derived monoterpenes identifies structural determinants of anti-inflammatory activity.Cátia Sousa et al.Scientific reports, 10(1), 7199-7199 (2020-05-01) TREM-1, a negative regulator of human osteoclastogenesis.Bitnara Lee et al.Immunology letters, 171, 50-59 (2016-02-09) COX-2 induces oncogenic micro RNA miR655 in human breast cancer.Mousumi Majumder et al.Scientific reports, 8(1), 327-327 (2018-01-13) Histone deacetylase 3 inhibition re-establishes synaptic tagging and capture in aging through the activation of nuclear factor kappa B.Mahima Sharma et al.Scientific reports, 5, 16616-16616 (2015-11-19) Galectin-3 Induces a Pro-degradative/inflammatory Gene Signature in Human Chondrocytes, Teaming Up with Galectin-1 in Osteoarthritis Pathogenesis.Daniela Weinmann et al.Scientific reports, 6, 39112-39112 (2016-12-17) MicroRNA-365 regulates IL-1β-induced catabolic factor expression by targeting HIF-2α in primary chondrocytes.Hyun Sook Hwang et al.Scientific reports, 7(1), 17889-17889 (2017-12-22) The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling.Jinjin Yu et al.Molecular and cellular biochemistry, 463(1-2), 203-210 (2019-10-24) COX-2 Elevates Oncogenic miR-526b in Breast Cancer by EP4 Activation.Mousumi Majumder et al.Molecular cancer research : MCR, 13(6), 1022-1033 (2015-03-04) TIAM1 inhibits lung fibroblast differentiation in pulmonary fibrosis.Zhicheng Huang et al.Experimental and therapeutic medicine, 14(5), 4254-4262 (2017-10-27) An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition.Helen L Young et al.The Journal of experimental medicine, 214(6), 1691-1710 (2017-04-30) Macrophage-derived CCL5 facilitates immune escape of colorectal cancer cells via the p65/STAT3-CSN5-PD-L1 pathway.Chao Liu et al.Cell death and differentiation, 27(6), 1765-1781 (2019-12-06) Identification of DKK-1 as a novel mediator of statin effects in human endothelial cells.Marta Pontremoli et al.Scientific reports, 8(1), 16671-16671 (2018-11-14) (-)-Epigallocatechin Gallate (EGCG) Enhances the Sensitivity of Colorectal Cancer Cells to 5-FU by Inhibiting GRP78/NF-κB/miR-155-5p/MDR1 Pathway.Xiaoqin La et al.Journal of agricultural and food chemistry, 67(9), 2510-2518 (2019-02-12) Vaccine adjuvant activity of a TLR4-activating synthetic glycolipid by promoting autophagy.Yi-Ju Chou et al.Scientific reports, 10(1), 8422-8422 (2020-05-23) Comparison of genotoxic versus nongenotoxic stabilization of p53 provides insight into parallel stress-responsive transcriptional networks.Allison N Catizone et al.Cell cycle (Georgetown, Tex.), 18(8), 809-823 (2019-04-11) Single-cell deconstruction of post-sepsis skeletal muscle and adipose tissue microenvironments.Dong Seong Cho et al.Journal of cachexia, sarcopenia and muscle, 11(5), 1351-1363 (2020-07-10) The NFkB pathway inhibitors Bay 11-7082 and parthenolide induce programmed cell death in anucleated ErythrocytesGhashghaeinia, et al. Cellular Physiology and Biochemistry, 27(1), 45-54 (2011) Busulfan and cyclosphamide induce liver inflammation through NLRP3 activation in mice after hematopoietic stem cell transplantationQiao J, et al. Scientific reports, 5, 17828-17828 (2015) Placental growth factor promotes epithelial-mesenchymal transition-like changes in ARPE-19 cells under hypoxia.Yi Zhang et al.Molecular vision, 24, 340-352 (2018-05-18) Ginsenoside Rh2 Ameliorates Atopic Dermatitis in NC/Nga Mice by Suppressing NF-kappaB-Mediated Thymic Stromal Lymphopoietin Expression and T Helper Type 2 Differentiation.Eunsu Ko et al.International journal of molecular sciences, 20(24) (2019-12-11) TREM2 suppresses the proinflammatory response to facilitate PRRSV infection via PI3K/NF-κB signaling.Zhenbang Zhu et al.PLoS pathogens, 16(5), e1008543-e1008543 (2020-05-14) Lysosomotropic beta blockers induce oxidative stress and IL23A production in Langerhans cells.Gerrit Müller et al.Autophagy, 16(8), 1380-1395 (2019-11-02) AEBP1 promotes epithelial-mesenchymal transition of gastric cancer cells by activating the NF-κB pathway and predicts poor outcome of the patients.Jun-Yan Liu et al.Scientific reports, 8(1), 11955-11955 (2018-08-12) Compensatory increase of VE-cadherin expression through ETS1 regulates endothelial barrier function in response to TNFα.Natalia Colás-Algora et al.Cellular and molecular life sciences : CMLS, 77(11), 2125-2140 (2019-08-10) Counter-regulatory paracrine actions of FGF-23 and 1,25(OH)2 D in macrophages.Xiaobin Han et al.FEBS letters, 590(1), 53-67 (2016-01-15) Interplay between the NF‑κB and hedgehog signaling pathways predicts prognosis in esophageal squamous cell carcinoma following neoadjuvant chemoradiotherapy.Lingyun Wei et al.International journal of molecular medicine, 41(5), 2961-2967 (2018-02-03) The TrkAIII oncoprotein inhibits mitochondrial free radical ROS-induced death of SH-SY5Y neuroblastoma cells by augmenting SOD2 expression and activity at the mitochondria, within the context of a tumour stem cell-like phenotype.Pierdomenico Ruggeri et al.PloS one, 9(4), e94568-e94568 (2014-04-17) Lysosomotropic beta blockers induce oxidative stress and IL23A production in Langerhans cells.Gerrit Müller et al.Autophagy, 16(8), 1380-1395 (2019-11-02) Dual inhibition of PI3K and mTOR by VS-5584 suppresses thrombus formation.Thomas Später et al.Platelets, 29(3), 277-287 (2017-05-16) The role of NF-kappa B signaling pathway in polyhexamethylene guanidine phosphate induced inflammatory response in mouse macrophage RAW264. 7 cellsKim HR, et al. Toxicology Letters, 233(2), 148-155 (2015) Combination treatment of podophyllotoxin and rutin promotes mouse Lgr5+ ve intestinal stem cells survival against lethal radiation injury through Wnt signaling.Bhargab Kalita et al.Apoptosis : an international journal on programmed cell death, 24(3-4), 326-340 (2019-02-07) Interplay between the NF‑κB and hedgehog signaling pathways predicts prognosis in esophageal squamous cell carcinoma following neoadjuvant chemoradiotherapy.Lingyun Wei et al.International journal of molecular medicine, 41(5), 2961-2967 (2018-02-03) Upregulation of neutrophil gelatinase-associated lipocalin by ErbB2 through nuclear factor-kappaB activation.Shau-Hsuan Li et al.Cancer research, 69(24), 9163-9168 (2009-12-03) HBsAg/β2GPI activates the NF‑κB pathway via the TLR4/MyD88/IκBα axis in hepatocellular carcinoma.Xue Jing et al.Oncology reports, 40(2), 1035-1045 (2018-06-20) Sulphur dioxide suppresses inflammatory response by sulphenylating NF-κB p65 at CysSiyao Chen et al.Clinical science (London, England : 1979), 131(21), 2655-2670 (2017-09-25) L5-LDL from ST-elevation myocardial infarction patients induces IL-1β production via LOX-1 and NLRP3 inflammasome activation in macrophages.Tzu-Ching Yang et al.American journal of physiology. Heart and circulatory physiology, 312(2), H265-H274 (2016-11-20) Paula Constanza Arriola Benitez et al.Frontiers in immunology, 10, 3036-3036 (2020-02-11)In human brucellosis, the liver is frequently affected. Brucella abortus triggers a profibrotic response on hepatic stellate cells (HSCs) characterized by inhibition of MMP-9 with concomitant collagen deposition and TGF-β1 secretion through type 4 secretion system (T4SS). Taking into account... Ginsenoside Rh2 Ameliorates Atopic Dermatitis in NC/Nga Mice by Suppressing NF-kappaB-Mediated Thymic Stromal Lymphopoietin Expression and T Helper Type 2 Differentiation.Eunsu Ko et al.International journal of molecular sciences, 20(24) (2019-12-11) Compensatory increase of VE-cadherin expression through ETS1 regulates endothelial barrier function in response to TNFα.Natalia Colás-Algora et al.Cellular and molecular life sciences : CMLS, 77(11), 2125-2140 (2019-08-10) TREM2 suppresses the proinflammatory response to facilitate PRRSV infection via PI3K/NF-κB signaling.Zhenbang Zhu et al.PLoS pathogens, 16(5), e1008543-e1008543 (2020-05-14) Keratinocytes in atopic dermatitis express abundant ΔNp73 regulating thymic stromal lymphopoietin production via NF-κB.Ayako Kumagai et al.Journal of dermatological science, 88(2), 175-183 (2017-06-29) The TrkAIII oncoprotein inhibits mitochondrial free radical ROS-induced death of SH-SY5Y neuroblastoma cells by augmenting SOD2 expression and activity at the mitochondria, within the context of a tumour stem cell-like phenotype.Pierdomenico Ruggeri et al.PloS one, 9(4), e94568-e94568 (2014-04-17) In vitro benchmarking of NF-κB inhibitors.Alexandria P Harrold et al.European journal of pharmacology, 873, 172981-172981 (2020-02-06) Mycoplasma hyorhinis induces epithelial-mesenchymal transition in gastric cancer cell MGC803 via TLR4-NF-kappaB signalingDuan H, et al. Cancer Letters, 354(2), 447-454 (2014) Inhibitory Effect of Low-Intensity Pulsed Ultrasound on the Expression of Lipopolysaccharide-Induced Inflammatory Factors in U937 Cells.Xuan Zhang et al.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 36(12), 2419-2429 (2017-06-11) Long Noncoding RNA DRAIC Inhibits Prostate Cancer Progression by Interacting with IKK to Inhibit NF-κB Activation.Shekhar Saha et al.Cancer research, 80(5), 950-963 (2020-01-05) Advanced glycation end products regulate interleukin-1β production in human placenta.Kotomi Seno et al.The Journal of reproduction and development, 63(4), 401-408 (2017-05-19) Neuronal Calcium Sensor 1 is up-regulated in response to stress to promote cell survival and motility in cancer cells.Henrike K Grosshans et al.Molecular oncology, 14(6), 1134-1151 (2020-04-03) The TLR4-IRE1α pathway activation contributes to palmitate-elicited lipotoxicity in hepatocytes.Chen Shen et al.Journal of cellular and molecular medicine, 22(7), 3572-3581 (2018-04-20) The role of miR-711 in cardiac cells in response to oxidative stress and its biogenesis: a study on H9C2 cells.Duo Zhao et al.Cellular & molecular biology letters, 25, 26-26 (2020-04-21) RNA stability regulates human T cell leukemia virus type 1 gene expression in chronically-infected CD4 T cells.Hsin-Ching Lin et al.Virology, 508, 7-17 (2017-05-10) Tim-3 aggravates podocyte injury in diabetic nephropathy by promoting macrophage activation via the NF-κB/TNF-α pathway.Huimin Yang et al.Molecular metabolism, 23, 24-36 (2019-03-14) Extra-Nuclear Signaling Pathway Involved in Progesterone-Induced Up-Regulations of p21cip1 and p27kip1 in Male Rat Aortic Smooth Muscle Cells.Hui-Chen Wang et al.PloS one, 10(5), e0125903-e0125903 (2015-05-02)

备注