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5-Isopropylidene-2,2-dimethyl-[1,3]dioxane-4,6-dione | CAS:2231-66-5
5-Isopropylidene-2,2-dimethyl-[1,3]dioxane-4,6-dione
  • 名称:5-异丙基亚基-2,2-二甲基-[1,3]二恶烷-4,6-二酮 | 5-Isopropylidene-2,2-dimethyl-[1,3]dioxane-4,6-dione
  • CAS号:2231-66-5
  • 别名:
  • 分子式:C9H12O4
  • 分子量:184.19
  • EINESC号:218-770-3

产品描述

物理化学性质

熔点 128 ºC (ethanol )**
密度 1.138±0.06 g/cm3 (20 º

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SDS

来源 SDS样本
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Neuropathology in mouse models of mucopolysaccharidosis type I, IIIA and IIIB.Fiona L Wilkinson et al.PloS one, 7(4), e35787-e35787 (2012-05-05) Characterization of inducible models of Tay-Sachs and related disease.Timothy J Sargeant et al.PLoS genetics, 8(9), e1002943-e1002943 (2012-10-03) Glycosphingolipid composition of MDA-MB-231 and MCF-7 human breast cancer cell lines.K Nohara et al.Breast cancer research and treatment, 48(2), 149-157 (1998-05-22) Abnormal gangliosides are localized in lipid rafts in Sanfilippo (MPS3a) mouse brain.G Dawson et al.Neurochemical research, 37(6), 1372-1380 (2012-04-10) Simultaneous development of acute disseminated encephalomyelitis and Guillain-Barré syndrome associated with H1N1 09 influenza vaccination.Takao Hoshino et al.Internal medicine (Tokyo, Japan), 51(12), 1595-1598 (2012-06-26) Altered levels of α-synuclein and sphingolipids in Batten disease lymphoblast cells.Sunyang Kang et al.Gene, 539(2), 181-185 (2014-02-19) Morphological alterations of the cornea in the mouse model of niemann-pick disease type c1.Marine Hovakimyan et al.Cornea, 30(7), 796-803 (2011-02-15) Molecular and biochemical characterization of a novel β-N-acetyl-D-hexosaminidase with broad substrate-spectrum from the Aisan corn borer, Ostrinia furnacalis.Fengyi Liu et al.International journal of biological sciences, 8(8), 1085-1096 (2012-09-20) Adjuvant ganglioside GM2-KLH/QS-21 vaccination versus observation after resection of primary tumor > 1.5 mm in patients with stage II melanoma: results of the EORTC 18961 randomized phase III trial.Alexander M M Eggermont et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(30), 3831-3837 (2013-09-11) Use of carbohydrate-conjugated nanoparticles for an integrated approach to functional imaging of glycans and understanding of their molecular mechanisms.Noriko Nagahori et al.Current pharmaceutical biotechnology, 13(14), 2612-2616 (2011-11-02) The Sda/GM2-glycan is a carbohydrate marker of porcine primordial germ cells and of a subpopulation of spermatogonia in cattle, pigs, horses and llama.K Klisch et al.Reproduction (Cambridge, England), 142(5), 667-674 (2011-09-08) Lysosomal dysfunction in a mouse model of Sandhoff disease leads to accumulation of ganglioside-bound amyloid-β peptide.Serene Keilani et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(15), 5223-5236 (2012-04-13) Genetically engineered humanized anti-ganglioside GM2 antibody against multiple organ metastasis produced by GM2-expressing small-cell lung cancer cells.Tadaaki Yamada et al.Cancer science, 102(12), 2157-2163 (2011-09-08) Neurotrophic effects of GM1 ganglioside, NGF, and FGF2 on canine dorsal root ganglia neurons in vitro.S Schwarz et al.Scientific reports, 10(1), 5380-5380 (2020-03-28) Fundus autofluorescence in Tay-Sachs disease.Maria Fernanda Abalem et al.JAMA ophthalmology, 132(7), 876-876 (2014-05-24) Ganglioside-embedding small bicelles for probing membrane-landing processes of intrinsically disordered proteins.Takumi Yamaguchi et al.Chemical communications (Cambridge, England), 49(12), 1235-1237 (2013-01-09) QM/MM study of the catalytic mechanism of GalNAc removal from GM2 ganglioside catalyzed by human β-hexosaminidaseA.Oscar Passos et al.The journal of physical chemistry. B, 115(49), 14751-14759 (2011-11-01) Experiences of dying, death and bereavement in motor neurone disease: a qualitative study.Bridget Whitehead et al.Palliative medicine, 26(4), 368-378 (2011-06-30) Switching on cytotoxicity by a single mutation at the heavy chain variable region of an anti-ganglioside antibody.Yuniel Fernández-Marrero et al.Molecular immunology, 48(8), 1059-1067 (2011-02-11) Structural characterization of the disialogangliosides of murine peritoneal macrophages.H C Yohe et al.Glycobiology, 7(8), 1215-1227 (1998-02-10) Functional interaction analysis of GM1-related carbohydrates and Vibrio cholerae toxins using carbohydrate microarray.Chang Sup Kim et al.Analytical chemistry, 84(15), 6884-6890 (2012-07-10) Elevation of GM2 ganglioside during ethanol-induced apoptotic neurodegeneration in the developing mouse brain.Mitsuo Saito et al.Journal of neurochemistry, 121(4), 649-661 (2012-03-01) Thymic involution and corticosterone level in Sandhoff disease model mice: new aspects the pathogenesis of GM2 gangliosidosis.Kazuhiko Matsuoka et al.Journal of inherited metabolic disease, 34(5), 1061-1068 (2011-05-21) Selective depletion of neuropathy-related antibodies from human serum by monolithic affinity columns containing ganglioside mimics.Kishore K R Tetala et al.Journal of medicinal chemistry, 54(10), 3500-3505 (2011-04-15) Cross-talks of glycosylphosphatidylinositol biosynthesis with glycosphingolipid biosynthesis and ER-associated degradation.Yicheng Wang et al.Nature communications, 11(1), 860-860 (2020-02-15) Therapeutic potential of intracerebroventricular replacement of modified human β-hexosaminidase B for GM2 gangliosidosis.Kazuhiko Matsuoka et al.Molecular therapy : the journal of the American Society of Gene Therapy, 19(6), 1017-1024 (2011-04-14) Altered distribution of the gangliosides GM1 and GM2 in Alzheimer's disease.Z Pernber et al.Dementia and geriatric cognitive disorders, 33(2-3), 174-188 (2012-05-11) Lyso-GM2 ganglioside: a possible biomarker of Tay-Sachs disease and Sandhoff disease.Takashi Kodama et al.PloS one, 6(12), e29074-e29074 (2011-12-30) Therapeutic effects of stem cells and substrate reduction in juvenile Sandhoff mice.J R Arthur et al.Neurochemical research, 37(6), 1335-1343 (2012-03-01) Case records of the Massachusetts General Hospital. Case 14-2014. An 11-month-old girl with developmental delay.Kalpathy S Krishnamoorthy et al.The New England journal of medicine, 370(19), 1830-1841 (2014-05-09) A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.Adam Shahine et al.Nature communications, 10(1), 56-56 (2019-01-06) Glycosphingolipid domains on cell plasma membrane.M Sorice et al.Bioscience reports, 19(3), 197-208 (1999-10-08) Acquired infantile abducens palsy associated with anti-GM2 antibodies.Kim A Smyth et al.Pediatric neurology, 44(6), 459-462 (2011-05-11) Anti-GM2 ganglioside antibodies are a biomarker for acute canine polyradiculoneuritis.Angie Rupp et al.Journal of the peripheral nervous system : JPNS, 18(1), 75-88 (2013-03-26) Integration of clinical data with a genome-scale metabolic model of the human adipocyte.Adil Mardinoglu et al.Molecular systems biology, 9, 649-649 (2013-03-21) In cellulo examination of a beta-alpha hybrid construct of beta-hexosaminidase A subunits, reported to interact with the GM2 activator protein and hydrolyze GM2 ganglioside.Incilay Sinici et al.PloS one, 8(3), e57908-e57908 (2013-03-14)
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