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(E)-4-Nonenal | CAS:2277-16-9
(E)-4-Nonenal
  • 名称:(E)-4-壬烯醛 | (E)-4-Nonenal
  • CAS号:2277-16-9
  • 别名:(E)-Non-4-enal; trans-4-Nonenal
  • 分子式:C9H16O
  • 分子量:140.22
  • EINESC号:

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物理化学性质

沸点 196 ºC
闪点 67 ºC
密度 0.834

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Here, we provide the first in vivo measurements of aerobic metabolism of the gut in a teleost fish by measuring gut blood... Functional Inhibition of Host Histone Deacetylases (HDACs) Enhances in vitro and in vivo Anti-mycobacterial Activity in Human Macrophages and in Zebrafish.Jôsimar D Moreira et al.Frontiers in immunology, 11, 36-36 (2020-03-03) Larval exposure to environmentally relevant concentrations of triclosan impairs metamorphosis and reproductive fitness in zebrafish.Amanda Stenzel et al.Reproductive toxicology (Elmsford, N.Y.), 87, 79-86 (2019-05-19) Arginine Vasopressin Modulates Ion and Acid/Base Balance by Regulating Cell Numbers of Sodium Chloride Cotransporter and H+-ATPase Rich Ionocytes.Sok-Keng Tong et al.International journal of molecular sciences, 21(11) (2020-06-04) A Conserved Notochord Enhancer Controls Pancreas Development in Vertebrates.João Pedro Amorim et al.Cell reports, 32(1), 107862-107862 (2020-07-09) Involvement of the GABAA receptor α subunit in the mode of action of etifoxine.César Mattei et al.Pharmacological research, 145, 104250-104250 (2019-05-07) Physiologic and biochemical measurements and response to noxious stimulation at various concentrations of MS-222 in koi (Cyprinus carpio).Jonathan Stockman et al.Veterinary anaesthesia and analgesia, 40(1), 35-47 (2012-06-26) Characterization of CD4-Positive Lymphocytes in the Antiviral Response of Olive Flounder (Paralichthys oliveceus) to Nervous Necrosis Virus.Jae Wook Jung et al.International journal of molecular sciences, 21(11) (2020-06-18) Pannexin 1 activation and inhibition is permeant-selective.Brian Skriver Nielsen et al.The Journal of physiology, 598(2), 361-379 (2019-11-08) Diel Variation in CC Chemokine Gene Expression in the Japanese Pufferfish Takifugu rubripes.Yuri Tsutsui et al.Marine biotechnology (New York, N.Y.), 22(5), 607-612 (2020-09-03) Trigeminal neuropathic pain development and maintenance in rats are suppressed by a positive modulator of α6 GABAA receptors.Dina Vasović et al.European journal of pain (London, England), 23(5), 973-984 (2019-01-12) Distinct inflammatory and wound healing responses to complex caudal fin injuries of larval zebrafish.Veronika Miskolci et al.eLife, 8 (2019-07-02) Chemicals affect color preference in rare minnow (Gobiocypris rarus).Ning Qiu et al.Environmental science and pollution research international, 27(18), 23206-23214 (2020-04-27) Repeated exposure of goldfish (Carassius auratus) to tricaine methanesulfonate (MS-222).Lysa Pam Posner et al.Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 44(2), 340-347 (2013-06-29) Exposure to seawater increases intestinal motility in euryhaline rainbow trout (Jeroen Brijs et al.The Journal of experimental biology, 220(Pt 13), 2397-2408 (2017-04-23) Metabolite profiles of striped marsh frog (Limnodynastes peronii) larvae exposed to the anti-androgenic fungicides vinclozolin and propiconazole are consistent with altered steroidogenesis and oxidative stress.Steven D Melvin et al.Aquatic toxicology (Amsterdam, Netherlands), 199, 232-239 (2018-04-17) Damage-induced reactive oxygen species regulateDanny LeBert et al.eLife, 7 (2018-01-18) Juvenile exposure to vinclozolin shifts sex ratios and impairs reproductive capacity of zebrafish.Yer Lor et al.Reproductive toxicology (Elmsford, N.Y.), 58, 111-118 (2015-10-02) NMR-based lipidomics of fish from a metal(loid) contaminated wetland show differences consistent with effects on cellular membranes and energy storage.Steven D Melvin et al.The Science of the total environment, 654, 284-291 (2018-11-18) Modulation of Cl- signaling and ion transport by recruitment of kinases and phosphatases mediated by the regulatory protein IRBIT.Laura Vachel et al.Science signaling, 11(554) (2018-11-01) Efficacy of Voriconazole against Aspergillus fumigatus Infection Depends on Host Immune Function.Emily E Rosowski et al.Antimicrobial agents and chemotherapy, 64(2) (2019-11-20) Developmental changes in head movement kinematics during swimming in Xenopus laevis tadpoles.Sara Hänzi et al.The Journal of experimental biology, 220(Pt 2), 227-236 (2016-11-05) Relationship Between Fluoroquinolone Structure and Neurotoxicity Revealed by Zebrafish Neurobehavior.Chaoqiang Xiao et al.Chemical research in toxicology, 31(4), 238-250 (2018-03-22) Steven D Melvin et al.Aquatic toxicology (Amsterdam, Netherlands), 184, 123-132 (2017-01-29)Pharmaceuticals are widely used for the treatment of various physical and psychological ailments. Due to incomplete removal during sewage treatment many pharmaceuticals are frequently detected in aquatic waterways at trace concentrations. The diversity of pharmaceutical contaminants and potential for complex... Pharmacokinetics of pirfenidone after topical administration in rabbit eye.Guoying Sun et al.Molecular vision, 17, 2191-2196 (2011-08-26) An ex vivo assay for screening glucocorticoid signaling disruption based on glucocorticoid-response gene transcription in Xenopus tails.Xiaoying Chen et al.Journal of environmental sciences (China), 66, 104-112 (2018-04-10) Determination of tricaine residues in fish by liquid chromatography.Cristina B Nochetto et al.Journal of AOAC International, 92(4), 1241-1247 (2009-09-01) Cxcr1 mediates recruitment of neutrophils and supports proliferation of tumor-initiating astrocytes in vivo.Davalyn Powell et al.Scientific reports, 8(1), 13285-13285 (2018-09-07) The zebrafish mutant lessen: an experimental model for congenital enteric neuropathies.L Uyttebroek et al.Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 28(3), 345-357 (2015-12-22) Differences in stress and disease resilience related to emergence time for first feeding in farmed rainbow trout (Oncorhynchus mykiss).Manuel Gesto et al.The Journal of experimental biology, 221(Pt 8) (2018-03-01) Distinct innate immune phagocyte responses to Aspergillus fumigatus conidia and hyphae in zebrafish larvae.Benjamin P Knox et al.Eukaryotic cell, 13(10), 1266-1277 (2014-06-01) Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing.Emily E Rosowski et al.PLoS pathogens, 14(8), e1007229-e1007229 (2018-08-03) Transgenerational effects of BPA on female reproduction.Stefania Santangeli et al.The Science of the total environment, 685, 1294-1305 (2019-07-06) Anesthetizing solar-powered sea slugs for photobiological studies.Sónia Cruz et al.The Biological bulletin, 223(3), 328-336 (2012-12-25) Epidermal regulation of bone morphogenesis through the development and regeneration of osteoblasts in the zebrafish scale.Miki Iwasaki et al.Developmental biology, 437(2), 105-119 (2018-03-11) Effects of the replacement of fishmeal by soy protein concentrate on growth performance, apparent digestibility, and retention of protein and amino acid in juvenile pearl gentian grouper.Yan Chen et al.PloS one, 14(12), e0222780-e0222780 (2019-12-24) Petromylidenes A⁻C: 2-Alkylidene Bile Salt Derivatives Isolated from Sea Lamprey (Petromyzon marinus).Ke Li et al.Marine drugs, 16(9) (2018-09-12) Anesthesia induces stress in Atlantic salmon (Salmo salar), Atlantic cod (Gadus morhua) and Atlantic halibut (Hippoglossus hippoglossus).Inger Hilde Zahl et al.Fish physiology and biochemistry, 36(3), 719-730 (2009-08-15) Accumulation and toxicity of multi-walled carbon nanotubes in Xenopus tropicalis tadpoles.Jianbin Zhao et al.Chemosphere, 257, 127205-127205 (2020-06-06) Overlapping but distinct topology for zebrafish V2R-like olfactory receptors reminiscent of odorant receptor spatial expression zones.Gaurav Ahuja et al.BMC genomics, 19(1), 383-383 (2018-05-25) Molecular characterization and expression analysis of olive flounder (Paralichthys olivaceus) phospholipase C gamma 1 and gamma 2.Soo Ji Woo et al.Fish & shellfish immunology, 63, 353-366 (2016-11-30) Jessica Kabutomori et al.Biology open, 7(4) (2018-03-14)Xenopus laevis oocytes are a valuable tool for investigating the function of membrane proteins. However, regulations around the world, specifically in Brazil, render the import of Xenopus laevis frogs impractical, and, in some cases, impossible. Here, as an alternative, we... Functional differences of three CXCL10 homologues in the giant spiny frog Quasipaa spinosa.Ze-Peng Liu et al.Developmental and comparative immunology, 109, 103719-103719 (2020-04-29) Effect of N-glycosylation on the transport activity of the peptide transporter PEPT1.Tamara Stelzl et al.American journal of physiology. Gastrointestinal and liver physiology, 310(2), G128-G141 (2015-11-21) The Effect of Fluence on Macrophage Kinetics, Oxidative Stress, and Wound Closure Using Real-Time In Vivo Imaging.Andre D Paredes et al.Photobiomodulation, photomedicine, and laser surgery, 37(1), 45-52 (2019-05-06) Developmental toxicity of dibutyl phthalate and citrate ester plasticizers in Xenopus laevis embryos.Yang Xu et al.Chemosphere, 204, 523-534 (2018-04-24) Investigating the effects of a sub-lethal metal mixture of Cu, Zn and Cd on bioaccumulation and ionoregulation in common carp, Cyprinus carpio.G Castaldo et al.Aquatic toxicology (Amsterdam, Netherlands), 218, 105363-105363 (2019-11-30) Glycine and GABA(A) ultra-sensitive ethanol receptors as novel tools for alcohol and brain research.Anna Naito et al.Molecular pharmacology, 86(6), 635-646 (2014-09-24) Zebrafish fin regeneration involves transient serotonin synthesis.Désirée König et al.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 27(4), 375-385 (2019-04-25) Use of tricaine methanesulfonate (MS222) for euthanasia of reptiles.C J Conroy et al.Journal of the American Association for Laboratory Animal Science : JAALAS, 48(1), 28-32 (2009-02-28) The effect of three anaesthetic protocols on the stress response in cane toads (Rhinella marina).Sandra E Hernández et al.Veterinary anaesthesia and analgesia, 39(6), 584-590 (2012-07-07) Re-evaluation of thyroid hormone signaling antagonism of tetrabromobisphenol A for validating the T3-induced Xenopus metamorphosis assay.Yao Wang et al.Journal of environmental sciences (China), 52, 325-332 (2017-03-04) Evaluation of rapid cooling and tricaine methanesulfonate (MS222) as methods of euthanasia in zebrafish (Danio rerio).Jolaine M Wilson et al.Journal of the American Association for Laboratory Animal Science : JAALAS, 48(6), 785-789 (2009-11-26) Juvenile-Specific Burst Firing of Terminal Nerve GnRH3 Neurons Suggests Novel Functions in Addition to Neuromodulation.Chie Umatani et al.Endocrinology, 159(4), 1678-1689 (2018-02-07) Characterization of Dermotheca sp. Infection in a midwestern state-endangered salamander (Ambystoma platineum) and a co-occurring common species (Ambystoma texanum).Laura Adamovicz et al.Parasitology, 147(3), 360-370 (2019-12-17) Reversed electrogenic sodium bicarbonate cotransporter 1 is the major acid loader during recovery from cytosolic alkalosis in mouse cortical astrocytes.Shefeeq M Theparambil et al.The Journal of physiology, 593(16), 3533-3547 (2015-05-21) How different rearing temperatures affect growth and stress status of Siberian sturgeon Acipenser baerii larvae.Lucia Aidos et al.Journal of fish biology, 96(4), 913-924 (2020-02-12) Differential response of olfactory sensory neuron populations to copper ion exposure in zebrafish.Maurizio Lazzari et al.Aquatic toxicology (Amsterdam, Netherlands), 183, 54-62 (2016-12-20) Validated LC-MS/MS method for simultaneous analysis of 21 cephalosporins in zebrafish for a drug toxicity study.Ying Liu et al.Analytical biochemistry, 558, 28-34 (2018-08-07) Molecular characterisation and expression of parathyroid hormone-related protein in the caudal neurosecretory system of the euryhaline flounder, Platichthys flesus.Weiqun Lu et al.General and comparative endocrinology, 249, 24-31 (2017-03-01) Evaluation and refinement of euthanasia methods for Xenopus laevis.Stéphanie L Torreilles et al.Journal of the American Association for Laboratory Animal Science : JAALAS, 48(5), 512-516 (2009-10-08) Diagnosis of Centrocestus formosanus Infection in Zebrafish (Danio rerio) in Italy: A Window to a New Globalization-Derived Invasive Microorganism.Antonino Pace et al.Animals : an open access journal from MDPI, 10(3) (2020-03-19) Genomic knockout of alms1 in zebrafish recapitulates Alström syndrome and provides insight into metabolic phenotypes.Jessica E Nesmith et al.Human molecular genetics, 28(13), 2212-2223 (2019-06-21) Baroreflex regulation affects ventilation in the cururu toad Rhinella schneideri.Lucas A Zena et al.The Journal of experimental biology, 219(Pt 22), 3605-3615 (2016-09-17) Distribution and Restoration of Serotonin-Immunoreactive Paraneuronal Cells During Caudal Fin Regeneration in Zebrafish.Désirée König et al.Frontiers in molecular neuroscience, 12, 227-227 (2019-10-17) Hyperinsulinemia induces insulin resistance and immune suppression via Ptpn6/Shp1 in zebrafish.Rubén Marín-Juez et al.The Journal of endocrinology, 222(2), 229-241 (2014-06-07) Neutrophil phagocyte oxidase activity controls invasive fungal growth and inflammation in zebrafish.Taylor J Schoen et al.Journal of cell science, 133(5) (2019-11-15) A protective role of autophagy in TDCIPP-induced developmental neurotoxicity in zebrafish larvae.Ruiwen Li et al.Aquatic toxicology (Amsterdam, Netherlands), 199, 46-54 (2018-04-02) The CXCR3-CXCL11 signaling axis mediates macrophage recruitment and dissemination of mycobacterial infection.Vincenzo Torraca et al.Disease models & mechanisms, 8(3), 253-269 (2015-01-13) Fgf signalling controls diverse aspects of fin regeneration.Eri Shibata et al.Development (Cambridge, England), 143(16), 2920-2929 (2016-07-13) Impaired autophagy bridges lysosomal storage disease and epithelial dysfunction in the kidney.Beatrice Paola Festa et al.Nature communications, 9(1), 161-161 (2018-01-13) Differential expression of fertility genes boule and dazl in Chinese sturgeon (Acipenser sinensis), a basal fish.Huan Ye et al.Cell and tissue research, 360(2), 413-425 (2015-01-17) Combined use of MS-222 (tricaine) and isoflurane extends anesthesia time and minimizes cardiac rhythm side effects in adult zebrafish.Wei-Chang Huang et al.Zebrafish, 7(3), 297-304 (2010-09-03) Effects of euthanasia method on stable-carbon and stable-nitrogen isotope analysis for an ectothermic vertebrate.Meredith A Atwood Rapid communications in mass spectrometry : RCM, 27(8), 909-913 (2013-03-16) Zebrafish Astroglial Morphology in the Olfactory Bulb Is Altered With Repetitive Peripheral Damage.Jackson Scheib et al.Frontiers in neuroanatomy, 14, 4-4 (2020-03-03) Hypoxia Has a Lasting Effect on Fast-Startle Behavior of the Tropical Fish Haemulon plumieri.Mayra A Sánchez-García et al.The Biological bulletin, 237(1), 48-62 (2019-08-24) Reproductive State Modulates Retinal Sensitivity to Light in Female Túngara Frogs.Caitlin E Leslie et al.Frontiers in behavioral neuroscience, 13, 293-293 (2020-02-23) Do Nanoparticle Physico-Chemical Properties and Developmental Exposure Window Influence Nano ZnO Embryotoxicity in Xenopus laevis?Patrizia Bonfanti et al.International journal of environmental research and public health, 12(8), 8828-8848 (2015-08-01) TrkB receptor antagonism inhibits stab injury induced proliferative response in adult zebrafish (Danio rerio) brain.Surendra Kumar Anand et al.Neuroscience letters, 672, 28-33 (2018-02-23) Bisphenol A alternatives bisphenol S and bisphenol F interfere with thyroid hormone signaling pathway in vitro and in vivo.Yin-Feng Zhang et al.Environmental pollution (Barking, Essex : 1987), 237, 1072-1079 (2017-11-18) Low-intensity pulsed ultrasound induces apoptosis in osteoclasts: Fish scales are a suitable model for the analysis of bone metabolism by ultrasound.Nobuo Suzuki et al.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 195, 26-31 (2016-02-07) Comparison the sensitivity of amphibian metamorphosis assays with NF 48 stage and NF 51 stage Xenopus laevis tadpoles.Yin-Feng Zhang et al.Toxicology mechanisms and methods, 29(6), 421-427 (2019-02-09) The effect of tricaine on use of the fluorescein test for detecting skin and corneal ulcers in fish.Michael W Davis et al.Journal of aquatic animal health, 20(2), 86-95 (2008-09-12) In vivo imaging of Mauthner axon regeneration, remyelination and synapses re-establishment after laser axotomy in zebrafish larvae.Bing-Bing Hu et al.Experimental neurology, 300, 67-73 (2017-11-03) Yap and Taz regulate retinal pigment epithelial cell fate.Joel B Miesfeld et al.Development (Cambridge, England), 142(17), 3021-3032 (2015-07-26) Pharmacological modulation of Acid-Sensing Ion Channels 1a and 3 by amiloride and 2-guanidine-4-methylquinazoline (GMQ).Thomas Besson et al.Neuropharmacology, 125, 429-440 (2017-08-15) Expression pattern of cdkl5 during zebrafish early development: implications for use as model for atypical Rett syndrome.Marta Vitorino et al.Molecular biology reports, 45(4), 445-451 (2018-05-13) Analysis of the respiratory component of heart rate variability in the Cururu toad Rhinella schneideri.Lucas A Zena et al.Scientific reports, 7(1), 16119-16119 (2017-11-25) Fiber Connections of the Caudal Corpus Cerebelli, with Special Reference to the Intrinsic Circuitry, in a Teleost (Oreochromis niloticus).Kosuke Imura et al.Brain, behavior and evolution, 89(1), 15-32 (2017-02-24) The basal function of teleost prolactin as a key regulator on ion uptake identified with zebrafish knockout models.Yuqin Shu et al.Scientific reports, 6, 18597-18597 (2016-01-05) Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function.Somayeh Jamali et al.Scientific reports, 5, 13605-13605 (2015-09-05) Social stress increases plasma cortisol and reduces forebrain cell proliferation in subordinate male zebrafish (Danio rerio).Jonathan Tea et al.The Journal of experimental biology, 222(Pt 2) (2018-12-12) Acute administration of THC impairs spatial but not associative memory function in zebrafish.Tim Ruhl et al.Psychopharmacology, 231(19), 3829-3842 (2014-03-19) Long-Range Optogenetic Control of Axon Guidance Overcomes Developmental Boundaries and Defects.James M Harris et al.Developmental cell, 53(5), 577-588 (2020-06-10) Genome-wide identification and characterization of glucose transporter (glut) genes in spotted sea bass (Lateolabrax maculatus) and their regulated hepatic expression during short-term starvation.Hongying Fan et al.Comparative biochemistry and physiology. Part D, Genomics & proteomics, 30, 217-229 (2019-03-27) Histopathological analysis of the olfactory epithelium of zebrafish (Danio rerio) exposed to sublethal doses of urea.Simone Bettini et al.Journal of anatomy, 228(1), 59-69 (2015-10-30) Prochloraz causes irreversible masculinization of zebrafish (Danio rerio).Lisa Baumann et al.Environmental science and pollution research international, 22(21), 16417-16422 (2014-08-29) Multiple cryoinjuries modulate the efficiency of zebrafish heart regeneration.Thomas Bise et al.Scientific reports, 10(1), 11551-11551 (2020-07-16) Development of the duct system during exocrine pancreas differentiation in the grass snake Natrix natrix (Lepidosauria, Serpentes).Magdalena Kowalska et al.Journal of morphology, 279(6), 724-746 (2018-02-22) Influence of Magnitude and Duration of Altered Gravity and Readaptation to 1 g on the Structure and Function of the Utricle in Toadfish, Opsanus tau.Richard Boyle et al.Frontiers in physiology, 9, 1469-1469 (2018-11-09) Matrix metalloproteinase 9 modulates collagen matrices and wound repair.Danny C LeBert et al.Development (Cambridge, England), 142(12), 2136-2146 (2015-05-28) The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection.Rui Zhang et al.PLoS pathogens, 15(2), e1007329-e1007329 (2019-03-01) Identification and characterization of POU class V family genes in Japanese red bellied newt, Cynops pyrrhogaster.Shun Hasegawa et al.Zygote (Cambridge, England), 27(5), 329-336 (2019-08-16) Microplastics in Small Waterbodies and Tadpoles from Yangtze River Delta, China.Lingling Hu et al.Environmental science & technology, 52(15), 8885-8893 (2018-07-24) The anti-estrogenicity of chronic exposure to semicarbazide in female Japanese flounders (Paralichthys olivaceus), and its potential mechanisms.Zonghao Yue et al.Marine pollution bulletin, 129(2), 806-812 (2017-11-05) Comparison of the effects of four anaesthetics on haematological and blood biochemical profiles in pikeperch (Sander lucioperca L.).Jiri Kristan et al.Neuro endocrinology letters, 33 Suppl 3, 66-71 (2013-01-29) Effect of tricainemethanesulfonate (MS222), clove oil and electro-anaesthesia on respiratory burst activity in whole blood and serum alternative complement response in rainbow trout (Oncorhynchus mykiss), during the narcosis stage.H Gholipour Kanani et al.Fish & shellfish immunology, 34(2), 692-696 (2012-12-12) Thermal sensitivity of motor control of muscle-powered versus elastically powered tongue projection in salamanders.Jeffrey A Scales et al.The Journal of experimental biology, 220(Pt 5), 938-951 (2016-12-14) Short-term cadmium exposure induces stress responses in frog (Pelophylax bergeri) skin organ culture.Francesca Simoncelli et al.Ecotoxicology and environmental safety, 122, 221-229 (2015-08-19) Optimization of In Vitro Culture Conditions of Sturgeon Germ Cells for Purpose of Surrogate Production.Xuan Xie et al.Animals : an open access journal from MDPI, 9(3) (2019-03-25) Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells.Lindsay C Spender et al.Oncotarget, 7(50), 81995-82012 (2016-11-12) Glycans in the intestinal peptide transporter PEPT1 contribute to function and protect from proteolysis.Tamara Stelzl et al.American journal of physiology. Gastrointestinal and liver physiology, 312(6), G580-G591 (2017-03-25) Enantioselective Bioaccumulation, Tissue Distribution, and Toxic Effects of Myclobutanil Enantiomers in Pelophylax nigromaculatus Tadpole.Cheng Cheng et al.Journal of agricultural and food chemistry, 65(15), 3096-3102 (2017-03-16) Molecular and transcriptional characterization of GTHs and mPRα during ovarian maturation in rock bream Oplegnathus fasciatus.Bao Shi et al.Journal of experimental zoology. Part A, Ecological genetics and physiology, 323(7), 430-444 (2015-06-04) Nutritional Status as the Key Modulator of Antioxidant Responses Induced by High Environmental Ammonia and Salinity Stress in European Sea Bass (Dicentrarchus labrax).Amit Kumar Sinha et al.PloS one, 10(8), e0135091-e0135091 (2015-08-05) Hair cell identity establishes labeled lines of directional mechanosensation.Marta Lozano-Ortega et al.PLoS biology, 16(7), e2004404-e2004404 (2018-07-20)
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