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4,5-Dimethylimidazole | CAS:2302-39-8
4,5-Dimethylimidazole
  • 名称:4,5-二甲基咪唑 | 4,5-Dimethylimidazole
  • CAS号:2302-39-8
  • 别名:
  • 分子式:C5H8N2
  • 分子量:96.13
  • EINESC号:218-954-3

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物理化学性质

熔点 121-122 ºC
密度 1.027

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来源 SDS样本
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Histaminergic and serotonergic receptor blocking substances from the medicinal plant Garcinia mangostana.N Chairungsrilerd et al.Planta medica, 62(5), 471-472 (1996-10-01) Mangosteen xanthones mitigate ovalbumin-induced airway inflammation in a mouse model of asthma.Ha-Young Jang et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(11), 4042-4050 (2012-09-05) Gamma-mangostin, a novel type of 5-hydroxytryptamine 2A receptor antagonist.N Chairungsrilerd et al.Naunyn-Schmiedeberg's archives of pharmacology, 357(1), 25-31 (1998-02-12) Inhibition of eukaryote protein kinases and of a cyclic nucleotide-binding phosphatase by prenylated xanthones.Z X Lu et al.Chemico-biological interactions, 114(1-2), 121-140 (1998-09-23) Discovery of γ-Mangostin as an Amyloidogenesis Inhibitor.Takeshi Yokoyama et al.Scientific reports, 5, 13570-13570 (2015-08-28) Active constituents against HIV-1 protease from Garcinia mangostana.S X Chen et al.Planta medica, 62(4), 381-382 (1996-08-01) Xanthones from mangosteen prevent lipopolysaccharide-mediated inflammation and insulin resistance in primary cultures of human adipocytes.Akkarach Bumrungpert et al.The Journal of nutrition, 139(6), 1185-1191 (2009-05-01) Effect of gamma-mangostin through the inhibition of 5-hydroxy-tryptamine2A receptors in 5-fluoro-alpha-methyltryptamine-induced head-twitch responses of mice.N Chairungsrilerd et al.British journal of pharmacology, 123(5), 855-862 (1998-04-16) [Novel types of receptor antagonists from the medicinal plant Garcinia mangostana].K Furukawa et al.Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 110 Suppl 1, 153P-158P (1998-03-21) New "hyphenated" CPC-HPLC-DAD-MS strategy for simultaneous isolation, analysis and identification of phytochemicals: application to xanthones from Garcinia mangostana.Thomas Michel et al.Analytical and bioanalytical chemistry, 404(10), 2963-2972 (2012-10-12) Gamma-mangostin, a micronutrient of mangosteen fruit, induces apoptosis in human colon cancer cells.Hui-Fang Chang et al.Molecules (Basel, Switzerland), 17(7), 8010-8021 (2012-07-05) Anti-inflammatory activity of mangostins from Garcinia mangostana.Lih-Geeng Chen et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46(2), 688-693 (2007-11-22) Inhibition of cyclooxygenase and prostaglandin E2 synthesis by gamma-mangostin, a xanthone derivative in mangosteen, in C6 rat glioma cells.Keigo Nakatani et al.Biochemical pharmacology, 63(1), 73-79 (2002-01-05) gamma-Mangostin inhibits inhibitor-kappaB kinase activity and decreases lipopolysaccharide-induced cyclooxygenase-2 gene expression in C6 rat glioma cells.Keigo Nakatani et al.Molecular pharmacology, 66(3), 667-674 (2004-08-24) γ-Mangostin increases serotonin 2A/2C, muscarinic, histamine and bradykinin receptor mRNA expression.Monrudee Sukma et al.Journal of ethnopharmacology, 135(2), 450-454 (2011-03-29) Mechanisms of vasorelaxation to gamma-mangostin in the rat aorta.Patcharin Tep-Areenan et al.Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 95 Suppl 12, S63-S68 (2013-03-22) Apoptotic effects of γ-mangostin from the fruit hull of Garcinia mangostana on human malignant glioma cells.Hui-Fang Chang et al.Molecules (Basel, Switzerland), 15(12), 8953-8966 (2010-12-09) Inhibition of human aldose reductase-like protein (AKR1B10) by α- and γ-mangostins, major components of pericarps of mangosteen.Midori Soda et al.Biological & pharmaceutical bulletin, 35(11), 2075-2080 (2012-11-06)
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