询 单
请 填 写 相 关 信 息
产品信息
产品名称
别名
CAS号
结构式 上传
联系方式
公司
联系人
电话
邮箱
内容
提交
中文版 English
请输入产品名称、CAS式、分子式
5,6-Dichloro-1,3-dihydro-2H-indol-2-one | CAS:71293-59-9
5,6-Dichloro-1,3-dihydro-2H-indol-2-one
  • 名称:5,6-二氯-1,3-二氢-2H-吲哚-2-酮 | 5,6-Dichloro-1,3-dihydro-2H-indol-2-one
  • CAS号:71293-59-9
  • 别名:
  • 分子式:C8H5Cl2NO
  • 分子量:202.04
  • EINESC号:

产品描述

物理化学性质

熔点 209-210 ºC**
密度 1.497±0.06 g/cm3 (20 º

安全数据

没有数据没有数据

SDS

来源 SDS样本
没有数据没有数据
产品合成路线
更多

名称 CAS号
更多
文章
同行评议文献
Evaluation of ursolic acid isolated from Ilex paraguariensis and derivatives on aromatase inhibition.Simone C B Gnoatto et al.European journal of medicinal chemistry, 43(9), 1865-1877 (2008-01-15) HPTLC-densitometry determination of triterpenic acids in Origanum vulgare, Rosmarinus officinalis and Syzygium aromaticum.Renata Nowak et al.Acta poloniae pharmaceutica, 70(3), 413-418 (2013-06-14) Ursolic acid improves domoic acid-induced cognitive deficits in mice.Dong-mei Wu et al.Toxicology and applied pharmacology, 271(2), 127-136 (2013-05-28) A phase I pharmacokinetic study of ursolic acid nanoliposomes in healthy volunteers and patients with advanced solid tumors.Zhongling Zhu et al.International journal of nanomedicine, 8, 129-136 (2013-01-16) Simultaneous determination of phenolic compounds and triterpenic acids in oregano growing wild in Greece by 31P NMR spectroscopy.Alexia Agiomyrgianaki et al.Magnetic resonance in chemistry : MRC, 50(11), 739-748 (2012-09-25) Isoprenylated flavonoids from the stem bark of Erythrina abyssinica.Long Cui et al.Journal of natural products, 70(6), 1039-1042 (2007-05-11) Two series of new semisynthetic triterpene derivatives: differences in anti-malarial activity, cytotoxicity and mechanism of action.Gloria N S da Silva et al.Malaria journal, 12, 89-89 (2013-03-19) Autophagy-dependent EIF2AK3 activation compromises ursolic acid-induced apoptosis through upregulation of MCL1 in MCF-7 human breast cancer cells.Chong Zhao et al.Autophagy, 9(2), 196-207 (2012-11-28) Triterpenoids from the leaves of Diospyros kaki (persimmon) and their inhibitory effects on protein tyrosine phosphatase 1B.Phuong Thien Thuong et al.Journal of natural products, 71(10), 1775-1778 (2008-09-19) Ursolic acid inhibits nuclear factor-κB signaling in intestinal epithelial cells and macrophages, and attenuates experimental colitis in mice.Jaeyoung Chun et al.Life sciences, 110(1), 23-34 (2014-07-06) [The quality standard study on Hugan qingzhi tablets].Ben-Jie Zhou et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(4), 644-647 (2012-10-02) Ursolic acid increases glucose uptake through the PI3K signaling pathway in adipocytes.Yonghan He et al.PloS one, 9(10), e110711-e110711 (2014-10-21) In Vitro Cytotoxicity of Oleanolic/Ursolic Acids-Loaded in PLGA Nanoparticles in Different Cell Lines.Amélia M Silva et al.Pharmaceutics, 11(8) (2019-07-28) Bioactive oleanane, lupane and ursane triterpene acid derivatives.Maria de L e Silva et al.Molecules (Basel, Switzerland), 17(10), 12197-12205 (2012-10-19) Ursolic acid induces autophagy in U87MG cells via ROS-dependent endoplasmic reticulum stress.Shuying Shen et al.Chemico-biological interactions, 218, 28-41 (2014-05-08) Ursolic acid inhibits tumor angiogenesis and induces apoptosis through mitochondrial-dependent pathway in Ehrlich ascites carcinoma tumor.Sarita Saraswati et al.Chemico-biological interactions, 206(2), 153-165 (2013-09-21) Pharmacology of oleanolic acid and ursolic acid.J Liu Journal of ethnopharmacology, 49(2), 57-68 (1995-12-01) RIPK1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved ER stress conditions.Y Estornes et al.Cell death & disease, 5, e1555-e1555 (2014-12-06) Effects of ursolic acid on the structural and morphological behaviours of dipalmitoyl lecithin vesicles.András Lőrincz et al.Biochimica et biophysica acta, 1848(5), 1092-1098 (2015-01-27) Ursolic acid sensitizes prostate cancer cells to TRAIL-mediated apoptosis.Seoung Woo Shin et al.Biochimica et biophysica acta, 1833(3), 723-730 (2012-12-19) Ursolic acid induces neural regeneration after sciatic nerve injury.Liu B, et al. Neural Regeneration Research, 8(27), 2510-2510 (2013) Bacterial biofilm inhibitors from Diospyros dendo.Jin-Feng Hu et al.Journal of natural products, 69(1), 118-120 (2006-01-31) Anticancer activity of the roots of Ichnocarpus frutescens R. Br. and isolated triterpenes.Narendra Kumar Singh et al.Pakistan journal of pharmaceutical sciences, 27(1), 187-191 (2014-01-01) Differential Anti-Proliferative and Anti-Migratory Activities of Ursolic Acid, 3-O-Acetylursolic Acid and Their Combination Treatments with Quercetin on Melanoma Cells.Aljawharah AlQathama et al.Biomolecules, 10(6) (2020-06-18) [Chemical constituents of Gentiana rhodantha].Yun Chen et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(3), 362-365 (2013-05-15) Pharmacomodulation on the 3-acetylursolic acid skeleton: Design, synthesis, and biological evaluation of novel N-{3-[4-(3-aminopropyl)piperazinyl]propyl}-3-O-acetylursolamide derivatives as antimalarial agents.Simone C B Gnoatto et al.Bioorganic & medicinal chemistry, 16(2), 771-782 (2007-10-31) The influence of herbal medicine ursolic acid on the uptake of rosuvastatin mediated by OATP1B1*1a and *5.Wen Jin Hua et al.European journal of drug metabolism and pharmacokinetics, 39(3), 221-230 (2014-04-17) Purity-activity relationships of natural products: the case of anti-TB active ursolic acid.Birgit U Jaki et al.Journal of natural products, 71(10), 1742-1748 (2008-09-19) Novel 3alpha-methoxyserrat-14-en-21beta-ol (PJ-1) and 3beta-methoxyserrat-14-en-21beta-ol (PJ-2)-curcumin, kojic acid, quercetin, and baicalein conjugates as HIV agents.Reiko Tanaka et al.Bioorganic & medicinal chemistry, 17(14), 5238-5246 (2009-06-12) Functional Characterization of Cucurbitadienol Synthase and Triterpene Glycosyltransferase Involved in Biosynthesis of Mogrosides from Siraitia grosvenorii.Longhai Dai et al.Plant & cell physiology, 56(6), 1172-1182 (2015-03-12) Synthesis and antiplasmodial activity of betulinic acid and ursolic acid analogues.Adrine M Innocente et al.Molecules (Basel, Switzerland), 17(10), 12003-12014 (2012-10-23) Ursolic acid: an anti-tumorigenic and chemopreventive activity. Minireview.L Novotný et al.Neoplasma, 48(4), 241-246 (2001-11-20) Delivery of ursolic acid (UA) in polymeric nanoparticles effectively promotes the apoptosis of gastric cancer cells through enhanced inhibition of cyclooxygenase 2 (COX-2).Hao Zhang et al.International journal of pharmaceutics, 441(1-2), 261-268 (2012-12-01) Inhibitory constituents of Nardostachys chinensis on nitric oxide production in RAW 264.7 macrophages.Ji Sang Hwang et al.Bioorganic & medicinal chemistry letters, 22(1), 706-708 (2011-11-15) Ursolic acid in cancer prevention and treatment: molecular targets, pharmacokinetics and clinical studies.Muthu K Shanmugam et al.Biochemical pharmacology, 85(11), 1579-1587 (2013-03-19) Study of skin anti-ageing and anti-inflammatory effects of dihydroquercetin, natural triterpenoids, and their synthetic derivatives.Chan Woo Lee et al.Bioorganicheskaia khimiia, 38(3), 374-381 (2012-09-25) Ursolic acid promotes the neuroprotection by activating Nrf2 pathway after cerebral ischemia in mice.Litao Li et al.Brain research, 1497, 32-39 (2013-01-02) Cytotoxic triterpenoids from the stems of Microtropis japonica.I-Hsiao Chen et al.Journal of natural products, 72(7), 1231-1236 (2009-06-19) Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities.Yi-Nan Zhang et al.Bioorganic & medicinal chemistry, 16(18), 8697-8705 (2008-08-19) Synthesis and biological evaluation of (±)-3-(2-(2-fluorobenzyloxy) naphthalen-6-yl)-2-aminopropanoic acid derivatives as novel PTP1B inhibitors.Liang-Peng Sun et al.European journal of medicinal chemistry, 46(9), 3630-3638 (2011-06-18) Suppression of AMF/PGI-mediated tumorigenic activities by ursolic acid in cultured hepatoma cells and in a mouse model.Wen-Ling Shih et al.Molecular carcinogenesis, 52(10), 800-812 (2012-05-03) Herbal tea extracts inhibit Cytochrome P450 3A4 in vitro.Sophie Dufay et al.The Journal of pharmacy and pharmacology, 66(10), 1478-1490 (2014-05-16) Ursolic acid inhibits the growth of colon cancer-initiating cells by targeting STAT3.Wenlong Wang et al.Anticancer research, 33(10), 4279-4284 (2013-10-15) Ursolic acid inhibits epithelial-mesenchymal transition by suppressing the expression of astrocyte-elevated gene-1 in human nonsmall cell lung cancer A549 cells.Kunmei Liu et al.Anti-cancer drugs, 24(5), 494-503 (2013-03-21) Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes.Cédric Genet et al.Journal of medicinal chemistry, 53(1), 178-190 (2009-11-17) Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.Xiaoan Wen et al.Journal of medicinal chemistry, 51(12), 3540-3554 (2008-06-04) Bioactive triterpenoids from Salvia species.Gülaçti Topçu Journal of natural products, 69(3), 482-487 (2006-03-28) Synthesis and cytotoxicity of novel ursolic acid derivatives containing an acyl piperazine moiety.Ming-Chuan Liu et al.European journal of medicinal chemistry, 58, 128-135 (2012-11-06) [Ursolic acid as antitumor agent and inductor of PTEN and brown fat].L M Bershteĭn Voprosy onkologii, 58(6), 744-747 (2012-01-01) Synthesis and in vitro biological activity of retinyl polyhydroxybenzoates, novel hybrid retinoid derivatives.Sungbum Kim et al.Bioorganic & medicinal chemistry letters, 19(2), 508-512 (2008-11-28) Ursolic acid: an anti- and pro-inflammatory triterpenoid.Yasutaka Ikeda et al.Molecular nutrition & food research, 52(1), 26-42 (2008-01-19) Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compounds.Sara Hoet et al.Journal of natural products, 70(8), 1360-1363 (2007-07-20) In vitro and in vivo anticancer activity evaluation of ursolic acid derivatives.Jing-Wei Shao et al.European journal of medicinal chemistry, 46(7), 2652-2661 (2011-04-26) Cytotoxic and PTP1B inhibitory activities from Erythrina abyssinica.Phi Hung Nguyen et al.Bioorganic & medicinal chemistry letters, 19(23), 6745-6749 (2009-10-20) Protein tyrosine phosphatase 1B inhibitory effects of depsidone and pseudodepsidone metabolites from the Antarctic lichen Stereocaulon alpinum.Changon Seo et al.Bioorganic & medicinal chemistry letters, 19(10), 2801-2803 (2009-04-14) Clinically useful anticancer, antitumor, and antiwrinkle agent, ursolic acid and related derivatives as medicinally important natural product.Nighat Sultana Journal of enzyme inhibition and medicinal chemistry, 26(5), 616-642 (2011-03-23) [Determination of oleanolic acid and ursolic acid in Damnacanthus indicus from different places by RP-hPLC].Ye-fen Cai et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(5), 694-696 (2012-12-12) Ursolic acid protects hippocampal neurons against kainate-induced excitotoxicity in rats.Shih YH, et al. Neuroscience Letters, 363(2), 136-140 (2004) Ursolic acid regulates high glucose-induced apoptosis.Chang Joo Oh et al.Free radical research, 41(6), 638-644 (2007-05-23) UP12, a novel ursolic acid derivative with potential for targeting multiple signaling pathways in hepatocellular carcinoma.Haiyan Dong et al.Biochemical pharmacology, 93(2), 151-162 (2014-12-20) Antituberculosis cycloartane triterpenoids from Radermachera boniana.Ngan B Truong et al.Journal of natural products, 74(5), 1318-1322 (2011-04-08) (-)-Epigallocatechin-3-gallate inhibits entry of hepatitis B virus into hepatocytes.Hsiu-Chen Huang et al.Antiviral research, 111, 100-111 (2014-09-28) Vindogentianine, a hypoglycemic alkaloid from Catharanthus roseus (L.) G. Don (Apocynaceae).Soon Huat Tiong et al.Fitoterapia, 102, 182-188 (2015-02-11) Triterpene saponins of Maesa lanceolata stem wood.Lawrence Onyango A Manguro et al.Journal of Asian natural products research, 14(11), 987-1001 (2012-10-27) Laetiporus sulphureus-fermented wheat bran enhanced the broiler growth performance by improving the intestinal microflora and inflammation status.W C Lin et al.Poultry science, 99(7), 3606-3616 (2020-07-04) Ursolic acid induces ER stress response to activate ASK1-JNK signaling and induce apoptosis in human bladder cancer T24 cells.Qing-you Zheng et al.Cellular signalling, 25(1), 206-213 (2012-09-25) Flavanones from the stem bark of Erythrina abyssinica.Long Cui et al.Bioorganic & medicinal chemistry, 16(24), 10356-10362 (2008-11-15) Ursolic, oleanolic and betulinic acids: antibacterial spectra and selectivity indexes.Fontanay S, et al. Journal of Ethnopharmacology, 120(2), 272-276 (2008) Antineoplastic agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms(1a,).George R Pettit et al.Journal of natural products, 71(3), 438-444 (2008-03-11) Anti-Diabetic Effects of Acankoreagenin from the Leaves of Acanthopanax Gracilistylus Herb in RIN-m5F Cells via Suppression of NF-κB Activation.Man-Xia Lu et al.Molecules (Basel, Switzerland), 23(4) (2018-04-20) Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.Zhongjie Liang et al.European journal of medicinal chemistry, 46(6), 2011-2021 (2011-03-29) Interactions of pentacyclic triterpene acids with cardiolipins and related phosphatidylglycerols in model systems.Marcin Broniatowski et al.Biochimica et biophysica acta, 1838(10), 2530-2538 (2014-06-08) Hawthorn ethanolic extracts with triterpenoids and flavonoids exert hepatoprotective effects and suppress the hypercholesterolemia-induced oxidative stress in rats.Ali Rezaei-Golmisheh et al.Iranian journal of basic medical sciences, 18(7), 691-699 (2015-09-12) Ursolic acid attenuates diabetic mesangial cell injury through the up-regulation of autophagy via miRNA-21/PTEN/Akt/mTOR suppression.Xinxing Lu et al.PloS one, 10(2), e0117400-e0117400 (2015-02-18) Regulation of the phosphatidylinositol 3-kinase-Akt and the mitogen-activated protein kinase pathways by ursolic acid in human endometrial cancer cells.Yumiko Achiwa et al.Bioscience, biotechnology, and biochemistry, 71(1), 31-37 (2007-01-11) Therapeutic Potential of Ocimum tenuiflorum as MPO Inhibitor with Implications for Atherosclerosis Prevention.Chandrakala Aluganti Narasimhulu et al.Journal of medicinal food, 18(5), 507-515 (2015-03-13) Ursolic acid promotes cancer cell death by inducing Atg5-dependent autophagy.Shuilong Leng et al.International journal of cancer, 133(12), 2781-2790 (2013-06-06) Ixorapeptide I and ixorapeptide II, bioactive peptides isolated from Ixora coccinea.Chia-Lin Lee et al.Bioorganic & medicinal chemistry letters, 20(24), 7354-7357 (2010-11-26) Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.Francisco J Prado-Prado et al.Bioorganic & medicinal chemistry, 18(6), 2225-2231 (2010-02-27) Simultaneous HPTLC analysis of ursolic acid, betulinic acid, stigmasterol and lupeol for the identification of four medicinal plants commonly available in the Indian market as Shankhpushpi.Neeraj Kumar Sethiya et al.Journal of chromatographic science, 53(5), 816-823 (2014-09-14) A novel C₂₅ sterol peroxide from the endophytic fungus Phoma sp. EA-122.Zi-Ming Chen et al.Zeitschrift fur Naturforschung. C, Journal of biosciences, 70(3-4), 93-96 (2015-05-30) Novel C-ring analogs of ursolic acid: synthesis and cytotoxic evaluation.Uppuluri V Mallavadhania et al.Natural product communications, 9(12), 1687-1690 (2015-01-30) Ursolic acid derivatives induce cell cycle arrest and apoptosis in NTUB1 cells associated with reactive oxygen species.Huang-Yao Tu et al.Bioorganic & medicinal chemistry, 17(20), 7265-7274 (2009-09-18) Validated spectrophotometric method for quantification of total triterpenes in plant matrices.Alessandra Moraes Pedrosa et al.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 28(1), 281-286 (2020-04-15) Ursolic acid stimulates mTORC1 signaling after resistance exercise in rat skeletal muscle.Riki Ogasawara et al.American journal of physiology. Endocrinology and metabolism, 305(6), E760-E765 (2013-08-01) Analysis of triterpenoids and phytosterols in vegetables by thin-layer chromatography coupled to tandem mass spectrometry.Katerina Naumoska et al.Journal of chromatography. A, 1381, 229-238 (2015-01-20) Three new triterpenes from Nerium oleander and biological activity of the isolated compounds.Liwei Fu et al.Journal of natural products, 68(2), 198-206 (2005-02-26) In vitro antituberculosis activities of the constituents isolated from Haloxylon salicornicum.Nazia Bibi et al.Bioorganic & medicinal chemistry letters, 20(14), 4173-4176 (2010-06-15) Scuteflorins A and B, dihydropyranocoumarins from Scutellaria lateriflora.Jing Li et al.Journal of natural products, 72(6), 983-987 (2009-06-27) [Chemical constituents from flower buds of Lonicera japonica].Fang Wang et al.Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(9), 1378-1385 (2013-08-16) Ursolic acid enhances pentobarbital-induced sleeping behaviors via GABAergic neurotransmission in mice.Jeon, SJ, et al. European Journal of Pharmacology, 762, 443-448 (2015) A novel C₂₅ sterol peroxide from the endophytic fungus Phoma sp. EA-122.Zi-Ming Chen et al.Zeitschrift fur Naturforschung. C, Journal of biosciences, 70(3-4), 93-96 (2015-05-30) Leonurus cardiaca L. herb--a derived extract and an ursolic acid as the factors affecting the adhesion capacity of Staphylococcus aureus in the context of infective endocarditis.Bartłomiej Micota et al.Acta biochimica Polonica, 61(2), 385-388 (2014-06-12) Three novel degraded steroids from cultures of the Basidiomycete Antrodiella albocinnamomea.Zi-Ming Chen et al.Steroids, 87, 21-25 (2014-06-01) A simple GC-MS method for the screening of betulinic, corosolic, maslinic, oleanolic and ursolic acid contents in commercial botanicals used as food supplement ingredients.Augusta Caligiani et al.Food chemistry, 136(2), 735-741 (2012-11-06) 11beta-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches.Judith M Rollinger et al.Bioorganic & medicinal chemistry, 18(4), 1507-1515 (2010-01-27) Simultaneous HPTLC analysis of ursolic acid, betulinic acid, stigmasterol and lupeol for the identification of four medicinal plants commonly available in the Indian market as Shankhpushpi.Neeraj Kumar Sethiya et al.Journal of chromatographic science, 53(5), 816-823 (2014-09-14) Discovery of novel Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase inhibitors.Renato F Freitas et al.Bioorganic & medicinal chemistry, 17(6), 2476-2482 (2009-03-04) Ursolic acid promotes cancer cell death by inducing Atg5-dependent autophagy.Shuilong Leng et al.International journal of cancer, 133(12), 2781-2790 (2013-06-06) Therapeutic Potential of Ocimum tenuiflorum as MPO Inhibitor with Implications for Atherosclerosis Prevention.Chandrakala Aluganti Narasimhulu et al.Journal of medicinal food, 18(5), 507-515 (2015-03-13) Ixorapeptide I and ixorapeptide II, bioactive peptides isolated from Ixora coccinea.Chia-Lin Lee et al.Bioorganic & medicinal chemistry letters, 20(24), 7354-7357 (2010-11-26) Regulation of the phosphatidylinositol 3-kinase-Akt and the mitogen-activated protein kinase pathways by ursolic acid in human endometrial cancer cells.Yumiko Achiwa et al.Bioscience, biotechnology, and biochemistry, 71(1), 31-37 (2007-01-11) Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.Francisco J Prado-Prado et al.Bioorganic & medicinal chemistry, 18(6), 2225-2231 (2010-02-27) In vitro antituberculosis activities of the constituents isolated from Haloxylon salicornicum.Nazia Bibi et al.Bioorganic & medicinal chemistry letters, 20(14), 4173-4176 (2010-06-15) Protein tyrosine phosphatase-1B inhibitory activity of isoprenylated flavonoids isolated from Erythrina mildbraedii.MinKyun Na et al.Journal of natural products, 69(11), 1572-1576 (2006-11-28) The mechanism of action of ursolic acid as insulin secretagogue and insulinomimetic is mediated by cross-talk between calcium and kinases to regulate glucose balance.Allisson Jhonatan Gomes Castro et al.Biochimica et biophysica acta, 1850(1), 51-61 (2014-10-15) Ursolic acid is a PPAR-α agonist that regulates hepatic lipid metabolism.Yaoyao Jia et al.Bioorganic & medicinal chemistry letters, 21(19), 5876-5880 (2011-08-23) Protein tyrosine phosphatase 1B inhibitors isolated from Morus bombycis.Duc Manh Hoang et al.Bioorganic & medicinal chemistry letters, 19(23), 6759-6761 (2009-10-23) Isolation of the protein tyrosine phosphatase 1B inhibitory metabolite from the marine-derived fungus Cosmospora sp. SF-5060.Changon Seo et al.Bioorganic & medicinal chemistry letters, 19(21), 6095-6097 (2009-09-29) Novel C-ring analogs of ursolic acid: synthesis and cytotoxic evaluation.Uppuluri V Mallavadhania et al.Natural product communications, 9(12), 1687-1690 (2015-01-30) Ursolic Acid Treatment Alleviates Diabetic Kidney Injury By Regulating The ARAP1/AT1R Signaling Pathway.Tian-Kui Ma et al.Diabetes, metabolic syndrome and obesity : targets and therapy, 12, 2597-2608 (2019-12-19) Ursolic acid, a potential PPARγ agonist, suppresses ovalbumin-induced airway inflammation and Penh by down-regulating IL-5, IL-13, and IL-17 in a mouse model of allergic asthma.Seung-Hyung Kim et al.European journal of pharmacology, 701(1-3), 131-143 (2012-12-04) Chemical profile and in vivo hypoglycemic effects of Syzygium jambos, Costus speciosus and Tapeinochilos ananassae plant extracts used as diabetes adjuvants in Puerto Rico.Jannette Gavillán-Suárez et al.BMC complementary and alternative medicine, 15, 244-244 (2015-07-23) Palbinone and triterpenes from Moutan Cortex (Paeonia suffruticosa, Paeoniaceae) stimulate glucose uptake and glycogen synthesis via activation of AMPK in insulin-resistant human HepG2 Cells.Do Thi Ha et al.Bioorganic & medicinal chemistry letters, 19(19), 5556-5559 (2009-09-01) The synthesis of ursolic acid derivatives with cytotoxic activity and the investigation of their preliminary mechanism of action.Yan-Qiu Meng et al.Bioorganic & medicinal chemistry, 17(2), 848-854 (2008-12-19) Inhibition of HepG2 cell proliferation by ursolic acid and polysaccharides via the downregulation of cyclooxygenase-2.Ling Liu et al.Molecular medicine reports, 9(6), 2505-2511 (2014-03-19) Synthesis of benzoyl phenyl benzoates as effective inhibitors for phospholipase A2 and hyaluronidase enzymes.Shaukath Ara Khanum et al.Bioorganic & medicinal chemistry letters, 15(18), 4100-4104 (2005-07-05) Accentuation of ursolic acid on muscarinic receptor-induced ANP secretion in beating rabbit atria.Hye Yoom Kim et al.Life sciences, 94(2), 145-150 (2013-12-18) Transcriptome analysis of the biofilm formed by methicillin-susceptible Staphylococcus aureus.Xiaojuan Tan et al.Scientific reports, 5, 11997-11997 (2015-07-08) The hypolipidemic effect of artesunate and ursolic acid in rats.Wang Yuliang et al.Pakistan journal of pharmaceutical sciences, 28(3), 871-874 (2015-05-26) Antiproliferative triterpenes from the leaves and twigs of Juglans sinensis on HSC-T6 cells.Heejung Yang et al.Journal of natural products, 74(4), 751-756 (2011-02-12) Transcriptome analysis of the biofilm formed by methicillin-susceptible Staphylococcus aureus.Xiaojuan Tan et al.Scientific reports, 5, 11997-11997 (2015-07-08) The hypolipidemic effect of artesunate and ursolic acid in rats.Wang Yuliang et al.Pakistan journal of pharmaceutical sciences, 28(3), 871-874 (2015-05-26) Accentuation of ursolic acid on muscarinic receptor-induced ANP secretion in beating rabbit atria.Hye Yoom Kim et al.Life sciences, 94(2), 145-150 (2013-12-18) Protein tyrosine phosphatase-1B inhibitory activity of isoprenylated flavonoids isolated from Erythrina mildbraedii.MinKyun Na et al.Journal of natural products, 69(11), 1572-1576 (2006-11-28) An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.Yunbao Liu et al.Journal of natural products, 73(7), 1193-1195 (2010-06-23) Synthesis of benzoyl phenyl benzoates as effective inhibitors for phospholipase A2 and hyaluronidase enzymes.Shaukath Ara Khanum et al.Bioorganic & medicinal chemistry letters, 15(18), 4100-4104 (2005-07-05) Effects of ursolic acid on glucose metabolism, the polyol pathway and dyslipidemia in non-obese type 2 diabetic mice.Jin Lee et al.Indian journal of experimental biology, 52(7), 683-691 (2014-07-26) 9,19-cyclolanostane derivatives from the roots of Actaea pachypoda.Zulfiqar Ali et al.Journal of natural products, 70(1), 107-110 (2007-01-27) Bioactive Phytochemicals from Wild Arbutus unedo L. Berries from Different Locations in Portugal: Quantification of Lipophilic Components.Daniela F S Fonseca et al.International journal of molecular sciences, 16(6), 14194-14209 (2015-06-26) [Chemical constituents from Gentiana striata].Cheng-Song Liu et al.Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(6), 908-910 (2012-12-15) New 5-deoxyflavonoids and their inhibitory effects on protein tyrosine phosphatase 1B (PTP1B) activity.Phi Hung Nguyen et al.Bioorganic & medicinal chemistry, 19(11), 3378-3383 (2011-05-17) Ursolic acid and rosiglitazone combination alleviates metabolic syndrome in high fat diet fed C57BL/6J mice.Arjunan Sundaresan et al.General physiology and biophysics, 31(3), 323-333 (2012-10-11) Modulating G-protein coupled receptor/G-protein signal transduction by small molecules suggested by virtual screening.Christina M Taylor et al.Journal of medicinal chemistry, 51(17), 5297-5303 (2008-08-19) Cytotoxic and NF-kappaB inhibitory constituents of Artocarpus rigida.Yulin Ren et al.Journal of natural products, 73(5), 949-955 (2010-04-14) Oleanolic acid and ursolic acid: research perspectives.Jie Liu Journal of ethnopharmacology, 100(1-2), 92-94 (2005-07-05) Inhibitory effect of chalcones and their derivatives from Glycyrrhiza inflata on protein tyrosine phosphatase 1B.Goo Yoon et al.Bioorganic & medicinal chemistry letters, 19(17), 5155-5157 (2009-07-28) Antiproliferative triterpenes from Melaleuca ericifolia.Fatma M Abdel Bar et al.Journal of natural products, 71(10), 1787-1790 (2008-10-02) Cytotoxic activity of ursolic acid derivatives obtained by isolation and oxidative derivatization.Kishor Mazumder et al.Molecules (Basel, Switzerland), 18(8), 8929-8944 (2013-07-31) Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents.Jin Tatsuzaki et al.Bioorganic & medicinal chemistry, 15(18), 6193-6199 (2007-06-27) Genome sequencing of herb Tulsi (Ocimum tenuiflorum) unravels key genes behind its strong medicinal properties.Atul K Upadhyay et al.BMC plant biology, 15, 212-212 (2015-09-01) Synthesis of 3-deoxypentacyclic triterpene derivatives as inhibitors of glycogen phosphorylase.Pu Zhang et al.Journal of natural products, 72(8), 1414-1418 (2009-08-01) Triterpenoid saponins from Symplocos lancifolia.Ivone Lucia Acebey-Castellon et al.Journal of natural products, 74(2), 163-168 (2011-02-04)
备注

Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.

Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).

名称 CAS号

相关产品

相关资讯

热门标签
询 单
请 填 写 相 关 信 息
产品信息
产品名称
别名
CAS号
结构式 上传
联系方式
公司
联系人
电话
邮箱
内容
提交