密度	1.294±0.06 g/cm3 (20 º

没有数据	没有数据

来源	SDS样本
没有数据	没有数据

产品合成路线

更多

名称	CAS号

更多

文章

同行评议文献

Breakdown of mucin as barrier to digestive enzymes in the ischemic rat small intestine.Marisol Chang et al.PloS one, 7(6), e40087-e40087 (2012-07-07) Significantly enhanced production of acarbose in fed-batch fermentation with the addition of S-adenosylmethionine.Li-Hui Sun et al.Journal of microbiology and biotechnology, 22(6), 826-831 (2012-05-11) Hypoglycemic properties of some preparations and compounds from Artemisia ludoviciana Nutt.Gerardo D Anaya-Eugenio et al.Journal of ethnopharmacology, 155(1), 416-425 (2014-06-04) Novel GAA mutations in patients with Pompe disease.Lauro Thiago Turaça et al.Gene, 561(1), 124-131 (2015-02-15) [The Study TO Prevent Non-Insulin Dependent Diabetes Mellitus trial (acarbose)].Rimei Nishimura Nihon rinsho. Japanese journal of clinical medicine, 63 Suppl 2, 478-482 (2005-03-23) Synthesis of 1,2,3-triazole glycoconjugates as inhibitors of α-glucosidases.David R da Rocha et al.Carbohydrate research, 350, 14-19 (2012-01-25) Exploring Antioxidant and Enzymes (A-Amylase and B-Glucosidase) Inhibitory Activity of Morinda lucida and Momordica charantia Leaves from Benin.Michaelle Chokki et al.Foods (Basel, Switzerland), 9(4) (2020-04-09) Human blood vessel organoids as a model of diabetic vasculopathy.Reiner A Wimmer et al.Nature, 565(7740), 505-510 (2019-01-18) Effects on lipid profile of dipeptidyl peptidase 4 inhibitors, pioglitazone, acarbose, and sulfonylureas: meta-analysis of placebo-controlled trials.Matteo Monami et al.Advances in therapy, 29(9), 736-746 (2012-08-28) Halogenated metabolites isolated from Penicillium citreonigrum.Wei-Hua Yuan et al.Chemistry & biodiversity, 11(7), 1078-1087 (2014-07-22) Acarbose in the prevention of cardiovascular disease in subjects with impaired glucose tolerance and type 2 diabetes mellitus.Sophie Delorme et al.Current opinion in pharmacology, 5(2), 184-189 (2005-03-23) Early improvement in carotid plaque echogenicity by acarbose in patients with acute coronary syndromes.Mitsumasa Hirano et al.Circulation journal : official journal of the Japanese Circulation Society, 76(6), 1452-1460 (2012-03-29) Lactobacillus strains isolated from infant faeces possess potent inhibitory activity against intestinal alpha- and beta-glucosidases suggesting anti-diabetic potential.Harsh Panwar et al.European journal of nutrition, 53(7), 1465-1474 (2014-01-15) Role of intestinal peptides and the autonomic nervous system in postprandial hypotension in patients with multiple system atrophy.Takeshi Fukushima et al.Journal of neurology, 260(2), 475-483 (2012-09-18) Synthesis, α-glucosidase inhibition and antioxidant activity of the 7-carbo-substituted 5-bromo-3-methylindazoles.Malose J Mphahlele et al.Bioorganic chemistry, 97, 103702-103702 (2020-03-09) Cardiovascular benefits of acarbose in impaired glucose tolerance and type 2 diabetes.Uwe Zeymer International journal of cardiology, 107(1), 11-20 (2005-12-13) Four flavonoid compounds from Phyllostachys edulis leaf extract retard the digestion of starch and its working mechanisms.Jun-Peng Yang et al.Journal of agricultural and food chemistry, 62(31), 7760-7770 (2014-07-16) Clinical utility of acarbose, an alpha-glucosidase inhibitor in cardiometabolic disorders.Sho-ichi Yamagishi et al.Current drug metabolism, 10(2), 159-163 (2009-03-12) Modified Regulatory Pathways to Approve Generic Drugs in the US and a Systematic Review of Their Outcomes.Aaron S Kesselheim et al.Drugs, 75(6), 633-650 (2015-03-31) Nimbandiolactone-21 and nimbandioloxyfuran, two new 28-norlimonoids from the leaves of Azadirachta indica (Meliaceae).Nhi Y Thi Nguyen et al.Journal of Asian natural products research, 21(9), 867-872 (2018-07-11) Effect of Moringa oleifera Leaf Powder on Postprandial Blood Glucose Response: In Vivo Study on Saharawi People Living in Refugee Camps.Alessandro Leone et al.Nutrients, 10(10) (2018-10-17) Efficacy and safety profile evaluation of acarbose alone and in association with other antidiabetic drugs: a systematic review.Giuseppe Derosa et al.Clinical therapeutics, 34(6), 1221-1236 (2012-05-09) Review of acarbose therapeutic strategies in the long-term treatment and in the prevention of type 2 diabetes.H W M Breuer International journal of clinical pharmacology and therapeutics, 41(10), 421-440 (2004-01-06) Effect of acarbose on vascular disease in patients with abnormal glucose tolerance.Markolf Hanefeld et al.Cardiovascular drugs and therapy, 22(3), 225-231 (2008-03-01) Rationale for and design of the Acarbose Cardiovascular Evaluation (ACE) trial.Rury R Holman et al.American heart journal, 168(1), 23-29 (2014-06-24) Antitumor effects and immune regulation activities of a purified polysaccharide extracted from Juglan regia.Wang Ruijun et al.International journal of biological macromolecules, 72, 771-775 (2014-09-30) Inhibitory activity of minor phlorotannins from Ecklonia cava on α-glucosidase.Sae Rom Park et al.Food chemistry, 257, 128-134 (2018-04-07) Comparative antioxidant and antidiabetic effects of Syzygium polyanthumleaf and Momordica charantia fruit extracts.Muhammad Jihad Sandikapura et al.Pakistan journal of pharmaceutical sciences, 31(2(Suppl.)), 623-635 (2018-04-08) Cardiovascular benefits and safety profile of acarbose therapy in prediabetes and established type 2 diabetes.Markolf Hanefeld Cardiovascular diabetology, 6, 20-20 (2007-08-19) Antibacterial, antioxidant and hypoglycaemic effects of Thymus capitatus (L.) Hoffmanns. et Link leaves' fractions.Liliana Iauk et al.Journal of enzyme inhibition and medicinal chemistry, 30(3), 360-365 (2014-07-18) Inhibitory potential of Turbinaria ornata against key metabolic enzymes linked to diabetes.P S Unnikrishnan et al.BioMed research international, 2014, 783895-783895 (2014-07-23) Study of Antiglycation, Hypoglycemic, and Nephroprotective Activities of the Green Dwarf Variety Coconut Water (Cocos nucifera L.) in Alloxan-Induced Diabetic Rats.Isabella F D Pinto et al.Journal of medicinal food, 18(7), 802-809 (2015-02-05) Usefulness of acarbose and dietary modifications to limit glycemic variability following Roux-en-Y gastric bypass as assessed by continuous glucose monitoring.Patrick Ritz et al.Diabetes technology & therapeutics, 14(8), 736-740 (2012-08-03) Influence of Acarbose on Plasma Glucose Fluctuations in Insulin-Treated Patients with Type 2 Diabetes: A Pilot Study.Feng-Fei Li et al.International journal of endocrinology, 2015, 903524-903524 (2015-12-08) Effect of acarbose on postprandial blood glucose concentrations in healthy cats fed low and high carbohydrate diets.Ranee Singh et al.Journal of feline medicine and surgery, 17(10), 848-857 (2014-10-26) Vindogentianine, a hypoglycemic alkaloid from Catharanthus roseus (L.) G. Don (Apocynaceae).Soon Huat Tiong et al.Fitoterapia, 102, 182-188 (2015-02-11) An effective and simplified scale-up strategy for acarbose fermentation based on the carbon source control.Kun-tai Li et al.World journal of microbiology & biotechnology, 28(2), 749-753 (2012-07-19) Podocyte as a potential target of inflammation: role of pioglitazone hydrochloride in patients with type 2 diabetes.Yan Xing et al.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 18(4), 493-498 (2012-03-24) Mechanistic investigation of anthocyanidin derivatives as α-glucosidase inhibitors.Jang Hoon Kim et al.Bioorganic chemistry, 87, 803-809 (2019-04-13) Melanogenesis inhibitory effect of aerial part of Pueraria thunbergiana in vitro and in vivo.EunByeol Han et al.Archives of dermatological research, 307(1), 57-72 (2014-07-27) Utility of an oxidation reaction for the spectrophotometric determination of acarbose in controlled release tablets at various simulated gastrointestinal media.Vivek Ranjan Sinha et al.Acta poloniae pharmaceutica, 69(1), 23-32 (2012-05-12) Hypolipidemic and hypoglycemic effects of Centella asiatica (L.) extract in vitro and in vivo.Nattapon Supkamonseni et al.Indian journal of experimental biology, 52(10), 965-971 (2014-10-28) Separation and characterization of polyphenolics from underutilized byproducts of fruit production (Choerospondias axillaris peels): inhibitory activity of proanthocyanidins against glycolysis enzymes.Qian Li et al.Food & function, 6(12), 3693-3701 (2015-10-08) Inhibition of Digestive Enzymes and Antioxidant Activity of Extracts from Fruits of Cornus alba, Cornus sanguinea subsp. hungarica and Cornus florida-A Comparative Study.Joanna Truba et al.Plants (Basel, Switzerland), 9(1) (2020-01-23) Pneumatosis coli induced by acarbose administration for diabetes mellitus. Case report and literature review.L Furio et al.Minerva gastroenterologica e dietologica, 52(3), 339-346 (2006-09-15) A column-switching HPLC-MS/MS method for mucopolysaccharidosis type I analysis in a multiplex assay for the simultaneous newborn screening of six lysosomal storage disorders.Antonina Gucciardi et al.Biomedical chromatography : BMC, 28(8), 1131-1139 (2014-01-23) [Acarbose-induced acute hepatitis. Report of two events in the same patient].J de la Vega et al.Gastroenterologia y hepatologia, 23(6), 282-284 (2004-08-25) Postprandial hyperglycaemia and vascular damage--the benefits of acarbose.Peter N Båvenholm et al.Diabetes & vascular disease research, 3(2), 72-79 (2006-10-25) Berry components inhibit α-glucosidase in vitro: synergies between acarbose and polyphenols from black currant and rowanberry.Ashley S Boath et al.Food chemistry, 135(3), 929-936 (2012-09-08) Comparative Cholinesterase, α-Glucosidase Inhibitory, Antioxidant, Molecular Docking, and Kinetic Studies on Potent Succinimide Derivatives.Ashfaq Ahmad et al.Drug design, development and therapy, 14, 2165-2178 (2020-07-02) A thin-layer chromatography-bioautographic method for detecting dipeptidyl peptidase IV inhibitors in plants.L H Gu et al.Journal of chromatography. A, 1411, 116-122 (2015-08-19) The complete genome sequence of the acarbose producer Actinoplanes sp. SE50/110.Patrick Schwientek et al.BMC genomics, 13, 112-112 (2012-03-27) [Cost-effectiveness of the addition of acarbose to the treatment of patients with type-2 diabetes in Spain].Carme Piñol et al.Gaceta sanitaria, 21(2), 97-104 (2007-04-11) The anthocyanins in black currants regulate postprandial hyperglycaemia primarily by inhibiting α-glucosidase while other phenolics modulate salivary α-amylase, glucose uptake and sugar transporters.Sisir Kumar Barik et al.The Journal of nutritional biochemistry, 78, 108325-108325 (2020-01-18) Anti-diabetic activity of peony seed oil, a new resource food in STZ-induced diabetic mice.Jianhui Su et al.Food & function, 6(9), 2930-2938 (2015-08-08) Enhanced production of acarbose and concurrently reduced formation of impurity c by addition of validamine in fermentation of Actinoplanes utahensis ZJB-08196.Ya-Ping Xue et al.BioMed research international, 2013, 705418-705418 (2013-03-14) Possible effects of dietary polyphenols on sugar absorption and digestion.Gary Williamson Molecular nutrition & food research, 57(1), 48-57 (2012-11-28) Hypoglycemic, antihyperglycemic, and antioxidant effects of the edible plant Anoda cristata.Krutzkaya Juárez-Reyes et al.Journal of ethnopharmacology, 161, 36-45 (2014-12-10) Bioactive diterpenoids and flavonoids from the aerial parts of Scoparia dulcis.Qing Liu et al.Journal of natural products, 77(7), 1594-1600 (2014-06-24) Acarbose treatment affects the serum levels of inflammatory cytokines and the gut content of bifidobacteria in Chinese patients with type 2 diabetes mellitus.Benli Su et al.Journal of diabetes, 7(5), 729-739 (2014-10-21) Alpha-glucosidase inhibitors 2012 - cardiovascular considerations and trial evaluation.Eberhard Standl et al.Diabetes & vascular disease research, 9(3), 163-169 (2012-04-18) Molecular basis for the recognition of long-chain substrates by plant α-glucosidases.Takayoshi Tagami et al.The Journal of biological chemistry, 288(26), 19296-19303 (2013-05-21) An optimized industrial fermentation processes for acarbose production by Actinoplanes sp. A56.Kun-tai Li et al.Bioresource technology, 118, 580-583 (2012-06-19) A new aldehyde compound from the fruit of Pandanus tectorius Parkinson ex Du Roi.Dinh Tri Mai et al.Natural product research, 29(15), 1437-1441 (2015-02-13) Sucrose induces vesicle accumulation and autophagy.Takahiro Higuchi et al.Journal of cellular biochemistry, 116(4), 609-617 (2014-11-13) Hypoglycemic, antihyperglycemic, and antioxidant effects of the edible plant Anoda cristata.Krutzkaya Juárez-Reyes et al.Journal of ethnopharmacology, 161, 36-45 (2014-12-10) Possible effects of dietary polyphenols on sugar absorption and digestion.Gary Williamson Molecular nutrition & food research, 57(1), 48-57 (2012-11-28) Enhanced production of acarbose and concurrently reduced formation of impurity c by addition of validamine in fermentation of Actinoplanes utahensis ZJB-08196.Ya-Ping Xue et al.BioMed research international, 2013, 705418-705418 (2013-03-14) A thin-layer chromatography-bioautographic method for detecting dipeptidyl peptidase IV inhibitors in plants.L H Gu et al.Journal of chromatography. A, 1411, 116-122 (2015-08-19) The complete genome sequence of the acarbose producer Actinoplanes sp. SE50/110.Patrick Schwientek et al.BMC genomics, 13, 112-112 (2012-03-27) Enzyme inhibitory and radical scavenging effects of some antidiabetic plants of Turkey.Nilüfer Orhan et al.Iranian journal of basic medical sciences, 17(6), 426-432 (2014-08-21) Evaluation of hypoglycemic effects of polyphenols and extracts from Penthorum chinense.Doudou Huang et al.Journal of ethnopharmacology, 163, 256-263 (2015-01-27) [Cost-effectiveness of the addition of acarbose to the treatment of patients with type-2 diabetes in Spain].Carme Piñol et al.Gaceta sanitaria, 21(2), 97-104 (2007-04-11) Antithrombotic and antidiabetic flavonoid glycosides from the grains of Sorghum bicolor (L.) Moench var. hwanggeumchal.Phi-Hung Nguyen et al.Archives of pharmacal research, 37(11), 1394-1402 (2014-06-25) Antidiabetic property of Symplocos cochinchinensis is mediated by inhibition of alpha glucosidase and enhanced insulin sensitivity.Kalathookunnel Antony Antu et al.PloS one, 9(9), e105829-e105829 (2014-09-04) Acarbose: oral anti-diabetes drug with additional cardiovascular benefits.Markolf Hanefeld et al.Expert review of cardiovascular therapy, 6(2), 153-163 (2008-02-06) Peptide modulators of alpha-glucosidase.Irena Roskar et al.Journal of diabetes investigation, 6(6), 625-631 (2015-11-07) Investigation of antihyperglycaemic activity of banana (Musa sp. var. Nanjangud rasa bale) pseudostem in normal and diabetic rats.Ramith Ramu et al.Journal of the science of food and agriculture, 95(1), 165-173 (2014-04-23) Treatment of impaired glucose tolerance with acarbose and its effect on intima-media thickness: a substudy of the STOP-NIDDM trial (study to prevent non-insulin-dependent diabetes mellitus).Markolf Hanefeld Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 12 Suppl 1, 56-59 (2006-04-22) Vicenin 2 isolated from Artemisia capillaris exhibited potent anti-glycation properties.Md Nurul Islam et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 69, 55-62 (2014-04-10) The ethanol extract of Eucommia ulmoides Oliv. leaves inhibits disaccharidase and glucose transport in Caco-2 cells.Yanyan Zhang et al.Journal of ethnopharmacology, 163, 99-105 (2015-01-27) Acarbose for the prevention of diabetes, hypertension, and cardiovascular disease in subjects with impaired glucose tolerance: the Study to Prevent Non-Insulin-Dependent Diabetes Mellitus (STOP-NIDDM) Trial.Jean-Louis Chiasson Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 12 Suppl 1, 25-30 (2006-04-22) Reducing the risk of type 2 diabetes: early identification of high-risk individuals and treatment with acarbose.Chang-Yu Pan Current diabetes reviews, 3(2), 141-148 (2008-01-29) A case of slowly progressive type 1 diabetes with insulin independence maintained for 10 years with α-glucosidase inhibitor monotherapy.Yuichiro Munakata et al.Internal medicine (Tokyo, Japan), 51(24), 3391-3394 (2012-12-22) Protein-protein interactions among enzymes of starch biosynthesis in high-amylose barley genotypes reveal differential roles of heteromeric enzyme complexes in the synthesis of A and B granules.Zaheer Ahmed et al.Plant science : an international journal of experimental plant biology, 233, 95-106 (2015-02-26) Spiroindolone Analogues as Potential Hypoglycemic with Dual Inhibitory Activity on α-Amylase and α-Glucosidase.Mezna Saleh Altowyan et al.Molecules (Basel, Switzerland), 24(12) (2019-06-28) Inhibitory Potential of Constituents from Osmanthus fragrans and Structural Analogues Against Advanced Glycation End Products, α-Amylase, α-Glucosidase, and Oxidative Stress.Ji-Yeon Yang et al.Scientific reports, 7, 45746-45746 (2017-04-01) [Effects of acarbose, alpha-glucosidase inhibitor in treatment of impaired glucose tolerance].Noriko Sakamoto et al.Nihon rinsho. Japanese journal of clinical medicine, 63 Suppl 2, 451-456 (2005-03-23) Novel benzoxazine-based aglycones block glucose uptake in vivo by inhibiting glycosidases.Hanumantharayappa Bharathkumar et al.PloS one, 9(7), e102759-e102759 (2014-07-23) Structural Basis for the Interconversion of Maltodextrins by MalQ, the Amylomaltase of Escherichia coli.Simon C Weiss et al.The Journal of biological chemistry, 290(35), 21352-21364 (2015-07-04) Enzymatic synthesis of Acarviosyl-maltooligosaccharides using disproportionating enzyme 1.Takayoshi Tagami et al.Bioscience, biotechnology, and biochemistry, 77(2), 312-319 (2013-02-09) Effects of acarbose on proinsulin and insulin secretion and their potential significance for the intermediary metabolism and cardiovascular system.Christoph Rosak et al.Current diabetes reviews, 5(3), 157-164 (2009-08-20) Seven-day subcutaneous continuous glucose monitoring demonstrates that treatment with acarbose attenuates late dumping syndrome in a woman with gastrectomy for gastric cancer.Silvio Buscemi et al.Diabetes research and clinical practice, 99(1), e1-e2 (2012-11-14) A review of the economic evidence for acarbose in the prevention of diabetes and cardiovascular events in individuals with impaired glucose tolerance.R G Josse et al.International journal of clinical practice, 60(7), 847-855 (2006-07-22) Investigation of bioequivalence of a new fixed-dose combination of acarbose and metformin with the corresponding loose combination as well as the drug-drug interaction potential between both drugs in healthy adult male subjects.S Kim et al.Journal of clinical pharmacy and therapeutics, 39(4), 424-431 (2014-05-09) Screening of α-glucosidase inhibitory activity from some plants of Apocynaceae, Clusiaceae, Euphorbiaceae, and Rubiaceae.Berna Elya et al.Journal of biomedicine & biotechnology, 2012, 281078-281078 (2011-12-22) In vitro studies to assess the antidiabetic, antiperoxidative, and radical scavenging potential of Stereospermum colais.M Priya Rani et al.Pharmaceutical biology, 50(10), 1254-1260 (2012-08-21) Antimicrobial and enzyme inhibitory activities of the constituents of Plectranthus madagascariensis (Pers.) Benth.Renata Kubínová et al.Journal of enzyme inhibition and medicinal chemistry, 29(5), 749-752 (2014-02-11) The hypoglycemic effect of a polysaccharide (GLP) from Gracilaria lemaneiformis and its degradation products in diabetic mice.Xubiao Liao et al.Food & function, 6(8), 2542-2549 (2015-06-27) Acarbose treatment enhances mid-regional pro-atrial natriuretic peptide concentrations in non-diabetic individuals: further evidence for a common cardiometabolic pathway?N Rudovich et al.Diabetologia, 55(12), 3392-3395 (2012-09-20) Novel Flavonoid Glycosides of Quercetin from Leaves and Flowers of Gaiadendron punctatum G.Don. (Violeta de Campo), used by the Saraguro Community in Southern Ecuador, Inhibit α-Glucosidase Enzyme.Héctor Cedeño et al.Molecules (Basel, Switzerland), 24(23) (2019-11-28) Hypoglycemic and antioxidant effects of Daraesoon (Actinidia arguta shoot) in animal models of diabetes mellitus.Ah-Yeon Lee et al.Nutrition research and practice, 9(3), 262-267 (2015-06-11) The anti-obesity potential of sigmoidin A.Solomon Habtemariam Pharmaceutical biology, 50(12), 1519-1522 (2012-09-18) Inhibitory effect of a weight-loss Chinese herbal formula RCM-107 on pancreatic α-amylase activity: Enzymatic and in silico approaches.Shiqi Luo et al.PloS one, 15(4), e0231815-e0231815 (2020-04-30) Multiple cerebral infarctions related to famotidine-induced eosinophilia.Chi-Shun Wu et al.Journal of neurology, 259(10), 2229-2231 (2012-05-16) Alpha glucosidase inhibitors.Sanjay Kalra JPMA. The Journal of the Pakistan Medical Association, 64(4), 474-476 (2014-05-29)

备注