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Stat3 inhibitor Stattic exhibits potent antitumor activity and induces chemo- and radio-sensitivity in nasopharyngeal carcinoma.Yunbao Pan et al.PloS one, 8(1), e54565-e54565 (2013-02-06) Reduction of RKIP expression promotes nasopharyngeal carcinoma invasion and metastasis by activating Stat3 signaling.Qiu-Yan He et al.Oncotarget, 6(18), 16422-16436 (2015-04-29) Epigenetic regulation of CpG promoter methylation in invasive prostate cancer cells.Lesley A Mathews et al.Molecular cancer, 9, 267-267 (2010-10-12) Cord blood mesenchymal stromal cell-conditioned medium protects endothelial cells via STAT3 signaling.Andreas Matthaeus Bader et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 34(3), 646-657 (2014-08-30) Increased STAT1 signaling in endocrine-resistant breast cancer.Rui Huang et al.PloS one, 9(4), e94226-e94226 (2014-04-15) Ischemia-reperfusion induces death receptor-independent necroptosis via calpain-STAT3 activation in a lung transplant setting.Hyunhee Kim et al.American journal of physiology. Lung cellular and molecular physiology, 315(4), L595-L608 (2018-07-20) IL-6 down-regulates HLA class II expression and IL-12 production of human dendritic cells to impair activation of antigen-specific CD4(+) T cells.Yosuke Ohno et al.Cancer immunology, immunotherapy : CII, 65(2), 193-204 (2016-01-14) Cigarette smoke-induced MMP2 and MMP9 secretion from aortic vascular smooth cells is mediated via the Jak/Stat pathway.Abhijit Ghosh et al.Human pathology, 46(2), 284-294 (2014-12-30) The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity.Matthew A Bill et al.Molecular cancer, 9, 165-165 (2010-06-26) Inhibition of a novel specific neuroglial integrin signaling pathway increases STAT3-mediated CNTF expression.Matthew P Keasey et al.Cell communication and signaling : CCS, 11, 35-35 (2013-05-23) Proatherogenic stimuli induce HuR in atherosclerosis through MAPK/ErK pathway.Ming Cheng et al.American journal of translational research, 11(4), 2317-2327 (2019-05-21) A new small-molecule Stat3 inhibitor.John S McMurray Chemistry & biology, 13(11), 1123-1124 (2006-11-23) Acquired resistance of pancreatic cancer cells to treatment with gemcitabine and HER-inhibitors is accompanied by increased sensitivity to STAT3 inhibition.Nikolaos Ioannou et al.International journal of oncology, 48(3), 908-918 (2016-01-20) Human dental pulp stem cells grown in neurogenic media differentiate into endothelial cells and promote neovasculogenesis in the mouse brain.Luzuriaga J, et al. Frontiers in Physiology, 10, 347-347 (2019) ADAM9 mediates the interleukin-6-induced Epithelial-Mesenchymal transition and metastasis through ROS production in hepatoma cells.Yinying Dong et al.Cancer letters, 421, 1-14 (2018-02-13) The STAT3 inhibitor stattic impairs cardiomyocyte mitochondrial function through increased reactive oxygen species formation.Kerstin Boengler et al.Current pharmaceutical design, 19(39), 6890-6895 (2013-04-18) Tagging of genomic STAT3 and STAT1 with fluorescent proteins and insertion of a luciferase reporter in the cyclin D1 gene provides a modified A549 cell line to screen for selective STAT3 inhibitors.Andrey Samsonov et al.PloS one, 8(7), e68391-e68391 (2013-08-21) EGFL7 is expressed in bone microenvironment and promotes angiogenesis via ERK, STAT3, and integrin signaling cascades.Shek Man Chim et al.Journal of cellular physiology, 230(1), 82-94 (2014-06-10) Leukemia inhibitory factor regulates the activation of inflammatory signals in macrophages and trophoblast cells.Jovane Hamelin-Morrissette et al.Molecular immunology, 120, 32-42 (2020-02-12) 6-Mercaptopurine reduces macrophage activation and gut epithelium proliferation through inhibition of GTPase Rac1.Goran Marinković et al.Inflammatory bowel diseases, 20(9), 1487-1495 (2014-07-17) FGF9 and FGF10 activate distinct signaling pathways to direct lung epithelial specification and branching.Yongjun Yin et al.Science signaling, 13(621) (2020-03-05) Arginase-II promotes melanoma migration and adhesion through enhancing hydrogen peroxide production and STAT3 signaling.Yi Yu et al.Journal of cellular physiology, 235(12), 9997-10011 (2020-05-30) Hyperglycemia enhances pancreatic cancer progression accompanied by elevations in phosphorylated STAT3 and MYC levels.Katsuhiko Sato et al.PloS one, 15(7), e0235573-e0235573 (2020-07-02) Oncostatin M stimulates cell migration and proliferation by down-regulating E-cadherin in HTR8/SVneo cell line through STAT3 activation.Hyun Sun Ko et al.Reproductive biology and endocrinology : RB&E, 11, 93-93 (2013-09-26) IL-9 induces VEGF secretion from human mast cells and IL-9/IL-9 receptor genes are overexpressed in atopic dermatitis.Nikolaos Sismanopoulos et al.PloS one, 7(3), e33271-e33271 (2012-03-14) Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M.Karen Kwofie et al.Respiratory research, 16, 14-14 (2015-04-08) Stattic: a small-molecule inhibitor of STAT3 activation and dimerization.Jochen Schust et al.Chemistry & biology, 13(11), 1235-1242 (2006-11-23) Proatherogenic stimuli induce HuR in atherosclerosis through MAPK/ErK pathwayCheng M, et al. American Journal of Translational Research, 11(4), 2317-2317 (2019) Mechanisms of paracrine cardioprotection by cord blood mesenchymal stromal cells.Andreas Matthaeus Bader et al.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 45(6), 983-992 (2014-02-25) Novel aroylated phenylenediamine compounds enhance antimicrobial defense and maintain airway epithelial barrier integrity.Iwona T Myszor et al.Scientific reports, 9(1), 7114-7114 (2019-05-10)

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