熔点	230 ºC
水溶性	略溶

安全说明书	S24/25

来源	SDS样本
Sigma-Aldrich	浏览或下载
TCI	浏览或下载
CDH	浏览或下载

产品合成路线

更多

名称	CAS号

更多

文章

同行评议文献

Snail1 controls bone mass by regulating Runx2 and VDR expression during osteoblast differentiation.Cristina A de Frutos et al.The EMBO journal, 28(6), 686-696 (2009-02-07) Use of SERMs for treatment in postmenopausal women.Joann V Pinkerton et al.The Journal of steroid biochemistry and molecular biology, 142, 142-154 (2014-01-01) Clearance of PML/RARA-bound promoters suffice to initiate APL differentiation.Adeline Vitaliano-Prunier et al.Blood, 124(25), 3772-3780 (2014-09-27) Essential role for TMEM100 in vascular integrity but limited contributions to the pathogenesis of hereditary haemorrhagic telangiectasia.Eun-Hye Moon et al.Cardiovascular research, 105(3), 353-360 (2014-12-30) Cav1.2 L-type calcium channels regulate stress coping behavior via serotonin neurons.Daniel G Ehlinger et al.Neuropharmacology, 144, 282-290 (2018-09-04) Resident mesenchymal vascular progenitors modulate adaptive angiogenesis and pulmonary remodeling via regulation of canonical Wnt signaling.Megan E Summers et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(8), 10267-10285 (2020-06-14) Ciliary IFT80 is essential for intervertebral disc development and maintenance.Xinhua Li et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(5), 6741-6756 (2020-04-01) Impact of conditional deletion of the pro-apoptotic BCL-2 family member BIM in mice.M J Herold et al.Cell death & disease, 5, e1446-e1446 (2014-10-10) Effect of obesity on aromatase inhibitor efficacy in postmenopausal, hormone receptor-positive breast cancer: a systematic review.S J Ioannides et al.Breast cancer research and treatment, 147(2), 237-248 (2014-08-15) Proliferation-Independent Initiation of Biliary Cysts in Polycystic Liver Diseases.Jean-Bernard Beaudry et al.PloS one, 10(6), e0132295-e0132295 (2015-07-01) Developmental Apoptosis Promotes a Disease-Related Gene Signature and Independence from CSF1R Signaling in Retinal Microglia.Sarah R Anderson et al.Cell reports, 27(7), 2002-2013 (2019-05-16) Lgr5+ stem and progenitor cells reside at the apex of a heterogeneous embryonic hepatoblast pool.Nicole Prior et al.Development (Cambridge, England), 146(12) (2019-05-31) Long-term cardiac and vascular disease outcomes following adjuvant tamoxifen therapy: current understanding of impact on physiology and overall survival.A A Onitilo et al.Minerva medica, 104(2), 141-153 (2013-03-22) Islet O-GlcNAcylation Is Required for Lipid Potentiation of Insulin Secretion through SERCA2.Amber Lockridge et al.Cell reports, 31(5), 107609-107609 (2020-05-07) CCN2 Expression by Tumor Stroma Is Required for Melanoma Metastasis.James Hutchenreuther et al.The Journal of investigative dermatology, 135(11), 2805-2813 (2015-07-15) Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.E Fontana et al.Current drug metabolism, 6(5), 413-454 (2005-10-27) Deltonin induced both apoptosis and autophagy in head and neck squamous carcinoma FaDu cell.Y L Xie et al.Neoplasma, 62(3), 419-431 (2015-04-14) Early embryonic NG2 glia are exclusively gliogenic and do not generate neurons in the brain.Wenhui Huang et al.Glia, 67(6), 1094-1103 (2019-02-07) Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies.Matthew P Goetz et al.Journal of the National Cancer Institute, 107(2), doi:10-doi:10 (2014-12-11) BMPRIA is required for osteogenic differentiation and RANKL expression in adult bone marrow mesenchymal stromal cells.Soma Biswas et al.Scientific reports, 8(1), 8475-8475 (2018-06-02) Dynamic gene expression patterns in animal models of early and late heart failure reveal biphasic-bidirectional transcriptional activation of signaling pathways.Janelle Rowell et al.Physiological genomics, 46(20), 779-787 (2014-08-28) A transgenic Prox1-Cre-tdTomato reporter mouse for lymphatic vessel research.Roberta Bianchi et al.PloS one, 10(4), e0122976-e0122976 (2015-04-08) No development of hypertension in the hyperuricemic liver-Glut9 knockout mouse.Frederic Preitner et al.Kidney international, 87(5), 940-947 (2015-01-08) Adipose-specific knockdown of Sirt1 results in obesity and insulin resistance by promoting exosomes release.Fang Li et al.Cell cycle (Georgetown, Tex.), 18(17), 2067-2082 (2019-07-13) Abundant expression of the membrane-anchored protease-regulator RECK in the anterior pituitary gland and its implication in the growth hormone/insulin-like growth factor 1 axis in mice.Shuichiro Ogawa et al.Molecular and cellular endocrinology, 508, 110790-110790 (2020-03-14) Metabolic and pathologic profiles of human LSS deficiency recapitulated in mice.Yoichi Wada et al.PLoS genetics, 16(2), e1008628-e1008628 (2020-02-27) Lineage fate of ductular reactions in liver injury and carcinogenesis.Simone Jörs et al.The Journal of clinical investigation, 125(6), 2445-2457 (2015-04-29) Analysis of glipizide binding to normal and glycated human serum albumin by high-performance affinity chromatography.Ryan Matsuda et al.Analytical and bioanalytical chemistry, 407(18), 5309-5321 (2015-04-29) Jagged1 is necessary for postnatal and adult neurogenesis in the dentate gyrus.Alfonso Lavado et al.Developmental biology, 388(1), 11-21 (2014-02-18) CSF-1 controls cerebellar microglia and is required for motor function and social interaction.Veronika Kana et al.The Journal of experimental medicine, 216(10), 2265-2281 (2019-07-28) Loss of Adult 5-HT1A Autoreceptors Results in a Paradoxical Anxiogenic Response to Antidepressant Treatment.Valérie Turcotte-Cardin et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(8), 1334-1346 (2018-12-16) Inducible transgenic mouse models.Thomas L Saunders Methods in molecular biology (Clifton, N.J.), 693, 103-115 (2010-11-17) Ai-lncRNA EGOT enhancing autophagy sensitizes paclitaxel cytotoxicity via upregulation of ITPR1 expression by RNA-RNA and RNA-protein interactions in human cancer.Shouping Xu et al.Molecular cancer, 18(1), 89-89 (2019-04-20) FDA-approved drug labeling for the study of drug-induced liver injury.Minjun Chen et al.Drug discovery today, 16(15-16), 697-703 (2011-06-01) Locating the binding sites of anticancer tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen on bovine serum albumin.P Bourassa et al.European journal of medicinal chemistry, 46(9), 4344-4353 (2011-07-23) Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.Edith Bellavance et al.Journal of medicinal chemistry, 52(23), 7488-7502 (2009-09-24) Angiopoietin-2 Inhibition Rescues Arteriovenous Malformation in a Smad4 Hereditary Hemorrhagic Telangiectasia Mouse Model.Angela M Crist et al.Circulation, 139(17), 2049-2063 (2019-02-13) Bmi1 enhances skeletal muscle regeneration through MT1-mediated oxidative stress protection in a mouse model of dystrophinopathy.Valentina Di Foggia et al.The Journal of experimental medicine, 211(13), 2617-2633 (2014-12-03) Venous thromboembolism prophylaxis for abdominal free tissue breast reconstruction: a multicenter survey.Onur Gilleard et al.Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 67(5), 733-735 (2014-01-07) Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells.Vincenza Caolo et al.eLife, 9 (2020-06-03) The investigation of miR-221-3p and PAK1 gene expressions in breast cancer cell lines.Sercan Ergun et al.Gene, 555(2), 377-381 (2014-12-03) Loss of Liver Kinase B1 (LKB1) in Beta Cells Enhances Glucose-stimulated Insulin Secretion Despite Profound Mitochondrial Defects.Avital Swisa et al.The Journal of biological chemistry, 290(34), 20934-20946 (2015-07-04) HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis.Yuqing Sun et al.Cancer cell, 34(4), 643-658 (2018-10-03) Mice with megalencephalic leukoencephalopathy with cysts: a developmental angle.Mohit Dubey et al.Annals of neurology, 77(1), 114-131 (2014-11-11) Altered radiation responses of breast cancer cells resistant to hormonal therapy.Lidiya Luzhna et al.Oncotarget, 6(3), 1678-1694 (2015-02-16) Early taste buds are from Shh+ epithelial cells of tongue primordium in distinction from mature taste bud cells which arise from surrounding tissue compartments.Naomi Kramer et al.Biochemical and biophysical research communications, 515(1), 149-155 (2019-05-28) Tissue-Resident PDGFRα+ Progenitor Cells Contribute to Fibrosis versus Healing in a Context- and Spatiotemporally Dependent Manner.Maria Paola Santini et al.Cell reports, 30(2), 555-570 (2020-01-16) Targeting glycolysis by 3-bromopyruvate improves tamoxifen cytotoxicity of breast cancer cell lines.Yasmin M Attia et al.BMC cancer, 15, 838-838 (2015-11-04) Ablation of the Ferroptosis Inhibitor Glutathione Peroxidase 4 in Neurons Results in Rapid Motor Neuron Degeneration and Paralysis.Liuji Chen et al.The Journal of biological chemistry, 290(47), 28097-28106 (2015-09-25) Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway.Wenyan Li et al.Proceedings of the National Academy of Sciences of the United States of America, 112(1), 166-171 (2014-12-24) Tac1-Expressing Neurons in the Periaqueductal Gray Facilitate the Itch-Scratching Cycle via Descending Regulation.Zheng-Run Gao et al.Neuron, 101(1), 45-59 (2018-12-18) Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells.Seungmin Han et al.Cell stem cell, 25(3), 342-356 (2019-08-20) Endothelial ZEB1 promotes angiogenesis-dependent bone formation and reverses osteoporosis.Rong Fu et al.Nature communications, 11(1), 460-460 (2020-01-25) IFT20 is required for the maintenance of cartilaginous matrix in condylar cartilage.Megumi Kitami et al.Biochemical and biophysical research communications, 509(1), 222-226 (2018-12-28) The use of adjuvant radiotherapy in elderly patients with early-stage breast cancer: changes in practice patterns after publication of Cancer and Leukemia Group B 9343.Manisha Palta et al.Cancer, 121(2), 188-193 (2014-12-10) Generating conditional knockout mice.Roland H Friedel et al.Methods in molecular biology (Clifton, N.J.), 693, 205-231 (2010-11-17) Activation of the intrinsic fibroinflammatory program in adult pancreatic acinar cells triggered by Hippo signaling disruption.Jun Liu et al.PLoS biology, 17(9), e3000418-e3000418 (2019-09-13) External validity of a trial comprised of elderly patients with hormone receptor-positive breast cancer.Willemien van de Water et al.Journal of the National Cancer Institute, 106(4), dju051-dju051 (2014-03-22) Establishment of the neurogenic boundary of the mouse retina requires cooperation of SOX2 and WNT signaling.Whitney E Heavner et al.Neural development, 9, 27-27 (2014-12-10) Dual origin of mesenchymal stem cells contributing to organ growth and repair.Jifan Feng et al.Proceedings of the National Academy of Sciences of the United States of America, 108(16), 6503-6508 (2011-04-06) Transcription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 2.Shurei Sugita et al.Proceedings of the National Academy of Sciences of the United States of America, 112(10), 3080-3085 (2015-03-04) Keratinocyte-derived TGFβ is not required to maintain skin immune homeostasis.Yi Yang et al.Journal of dermatological science, 94(2), 290-297 (2019-05-24) Tamoxifen for prevention of breast cancer: extended long-term follow-up of the IBIS-I breast cancer prevention trial.Jack Cuzick et al.The Lancet. Oncology, 16(1), 67-75 (2014-12-17) Effects of 7-O substitutions on estrogenic and anti-estrogenic activities of daidzein analogues in MCF-7 breast cancer cells.Quan Jiang et al.Journal of medicinal chemistry, 53(16), 6153-6163 (2010-07-31) NF1 regulation of RAS/ERK signaling is required for appropriate granule neuron progenitor expansion and migration in cerebellar development.Efrain Sanchez-Ortiz et al.Genes & development, 28(21), 2407-2420 (2014-11-05) Loss of Cdk2 and cyclin A2 impairs cell proliferation and tumorigenesis.Lakshmi Gopinathan et al.Cancer research, 74(14), 3870-3879 (2014-05-08) Two nested developmental waves demarcate a compartment boundary in the mouse lung.Denise Martinez Alanis et al.Nature communications, 5, 3923-3923 (2014-06-01) High-Throughput Mapping of Long-Range Neuronal Projection Using In Situ Sequencing.Xiaoyin Chen et al.Cell, 179(3), 772-786 (2019-10-19) YY1 regulates skeletal muscle regeneration through controlling metabolic reprogramming of satellite cells.Fengyuan Chen et al.The EMBO journal, 38(10) (2019-04-14) Effects of folic acid on growth performance, ruminal fermentation, nutrient digestibility and urinary excretion of purine derivatives in post-weaned dairy calves.Cong Wang et al.Archives of animal nutrition, 73(1), 18-29 (2018-11-27) Tamoxifen affects the histology and hepatopancreatic lipid metabolism of swimming crab Portunus trituberculatus.Meimei Liu et al.Aquatic toxicology (Amsterdam, Netherlands), 213, 105220-105220 (2019-06-16) Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates.Louis Faure et al.Nature communications, 11(1), 4175-4175 (2020-08-23) Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis.Wassim A Basheer et al.Journal of molecular and cellular cardiology, 88, 1-13 (2015-09-20) Reduction of AMPA receptor activity on mature oligodendrocytes attenuates loss of myelinated axons in autoimmune neuroinflammation.Kirsten S Evonuk et al.Science advances, 6(2), eaax5936-eaax5936 (2020-01-15) ABCG2pos lung mesenchymal stem cells are a novel pericyte subpopulation that contributes to fibrotic remodeling.Shennea Marriott et al.American journal of physiology. Cell physiology, 307(8), C684-C698 (2014-08-15) miR-378a-3p modulates tamoxifen sensitivity in breast cancer MCF-7 cells through targeting GOLT1A.Kazuhiro Ikeda et al.Scientific reports, 5, 13170-13170 (2015-08-11) Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction.Sarah A Dick et al.Nature immunology, 20(1), 29-39 (2018-12-13) APC is required for muscle stem cell proliferation and skeletal muscle tissue repair.Alice Parisi et al.The Journal of cell biology, 210(5), 717-726 (2015-08-26) Parallel Lineage-Tracing Studies Establish Fibroblasts as the Prevailing In Vivo Adipocyte Progenitor.Paola Cattaneo et al.Cell reports, 30(2), 571-582 (2020-01-16) Hormone therapy in premenopausal women with early-stage breast cancer.Hope S Rugo The New England journal of medicine, 371(2), 175-176 (2014-07-10) Neuronal O-GlcNAc transferase regulates appetite, body weight, and peripheral insulin resistance.Chun-Ling Dai et al.Neurobiology of aging, 70, 40-50 (2018-06-27) A septo-temporal molecular gradient of sfrp3 in the dentate gyrus differentially regulates quiescent adult hippocampal neural stem cell activation.Jiaqi Sun et al.Molecular brain, 8, 52-52 (2015-09-05) Essential roles of epithelial bone morphogenetic protein signaling during prostatic development.Akiko Omori et al.Endocrinology, 155(7), 2534-2544 (2014-04-16) Morphological remodeling during recovery of the neuromuscular junction from terminal Schwann cell ablation in adult mice.Robert Louis Hastings et al.Scientific reports, 10(1), 11132-11132 (2020-07-09) The hyperpolarization-activated cyclic nucleotide-gated 4 channel as a potential anti-seizure drug target.Qays Kharouf et al.British journal of pharmacology, 177(16), 3712-3729 (2020-05-05) Different neuronal populations mediate inflammatory pain analgesia by exogenous and endogenous opioids.Xin-Yan Zhang et al.eLife, 9 (2020-06-11) The generation and characterization of novel Col1a1FRT-Cre-ER-T2-FRT and Col1a1FRT-STOP-FRT-Cre-ER-T2 mice for sequential mutagenesis.Minsi Zhang et al.Disease models & mechanisms, 8(9), 1155-1166 (2015-07-18) Antitumor agents. 254. Synthesis and biological evaluation of novel neo-tanshinlactone analogues as potent anti-breast cancer agents.Xihong Wang et al.Journal of medicinal chemistry, 49(18), 5631-5634 (2006-09-01) Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia.Bon-Kyoung Koo et al.Proceedings of the National Academy of Sciences of the United States of America, 112(24), 7548-7550 (2015-05-30) SRC drives growth of antiestrogen resistant breast cancer cell lines and is a marker for reduced benefit of tamoxifen treatment.Sarah L Larsen et al.PloS one, 10(2), e0118346-e0118346 (2015-02-24) DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.Chun-Wei Chen et al.Nature medicine, 21(4), 335-343 (2015-03-31) Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis.Stanley C W Lee et al.Blood, 126(2), 167-175 (2015-06-04) Regulator of G Protein Signaling 6 Facilities Cardiac Hypertrophy by Activating Apoptosis Signal-Regulating Kinase 1-P38/c-JUN N-Terminal Kinase 1/2 Signaling.Zhijun Huang et al.Journal of the American Heart Association, 7(19), e009179-e009179 (2018-10-30) Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization.Keisuke Yanagida et al.Developmental cell, 52(6), 779-793 (2020-02-16) MicroRNAs participate in the murine oligodendroglial response to perinatal hypoxia-ischemia.Derin Birch et al.Pediatric research, 76(4), 334-340 (2014-07-09) Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons.James M Clegg et al.Neural development, 10, 26-26 (2015-11-02) VEGF-C is required for intestinal lymphatic vessel maintenance and lipid absorption.Harri Nurmi et al.EMBO molecular medicine, 7(11), 1418-1425 (2015-10-16) Inducible deletion of connexin 40 in adult mice causes hypertension and disrupts pressure control of renin secretion.Melanie Gerl et al.Kidney international, 87(3), 557-563 (2014-09-18) Cell-Specific Transcriptional Responses to Heat Shock in the Mouse Utricle Epithelium.Erica Sadler et al.Frontiers in cellular neuroscience, 14, 123-123 (2020-06-13) Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis.Thomas Moore-Morris et al.The Journal of clinical investigation, 124(7), 2921-2934 (2014-06-18) Uptake of tamoxifen in consecutive premenopausal women under surveillance in a high-risk breast cancer clinic.L S Donnelly et al.British journal of cancer, 110(7), 1681-1687 (2014-03-07) A perisinusoidal niche for extramedullary haematopoiesis in the spleen.Christopher N Inra et al.Nature, 527(7579), 466-471 (2015-11-17) Introduction of human pharmaceuticals from wastewater treatment plants into the aquatic environment: a rural perspective.Carolina Nebot et al.Environmental science and pollution research international, 22(14), 10559-10568 (2015-03-05) Discoidin domain receptor 1 regulates endochondral ossification through terminal differentiation of chondrocytes.Liang-Yin Chou et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(4), 5767-5781 (2020-03-05) Liraglutide improves pancreatic Beta cell mass and function in alloxan-induced diabetic mice.Kanako Tamura et al.PloS one, 10(5), e0126003-e0126003 (2015-05-06) Metal complexes as a promising source for new antibiotics.Angelo Frei et al.Chemical science, 11(10), 2627-2639 (2020-03-25) The Wilms' tumor suppressor gene regulates pancreas homeostasis and repair.Laura Ariza et al.PLoS genetics, 15(2), e1007971-e1007971 (2019-02-15) Mitochondria-Endoplasmic Reticulum Contacts in Reactive Astrocytes Promote Vascular Remodeling.Jana Gӧbel et al.Cell metabolism, 31(4), 791-808 (2020-03-30) m-Carborane bisphenol structure as a pharmacophore for selective estrogen receptor modulators.Takumi Ogawa et al.Bioorganic & medicinal chemistry letters, 16(15), 3943-3946 (2006-06-01) Dedifferentiation of committed epithelial cells into stem cells in vivo.Purushothama Rao Tata et al.Nature, 503(7475), 218-223 (2013-11-08) Function of astrocyte MyD88 in high-fat-diet-induced hypothalamic inflammation.Sungho Jin et al.Journal of neuroinflammation, 17(1), 195-195 (2020-06-21) Functional role of serotonin in insulin secretion in a diet-induced insulin-resistant state.Kyuho Kim et al.Endocrinology, 156(2), 444-452 (2014-11-27) Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss.Angeliki M Nikolakopoulou et al.Nature neuroscience, 22(7), 1089-1098 (2019-06-27) Inducible expression of hyperactive Syk in B cells activates Blimp-1-dependent terminal differentiation.Hug E, Hobeika E, Reth M, et al. Oncogene, 33(28), 3730-3741 (2014) Isochaihulactone analogues: synthesis and anti-proliferative activity of novel dibenzylbutyrolactones.Babak Heidary Alizadeh et al.European journal of medicinal chemistry, 45(12), 5979-5984 (2010-11-03) Astrocyte uncoupling as a cause of human temporal lobe epilepsy.Peter Bedner et al.Brain : a journal of neurology, 138(Pt 5), 1208-1222 (2015-03-15) Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging.Mikihito Hayashi et al.Cell metabolism, 29(3), 627-637 (2019-01-22) Estrogen regulation of anti-apoptotic Bcl-2 family member Mcl-1 expression in breast cancer cells.Jennifer L Schacter et al.PloS one, 9(6), e100364-e100364 (2014-06-28) Development of new estrogen receptor-targeting therapeutic agents for tamoxifen-resistant breast cancer.Quan Jiang et al.Future medicinal chemistry, 5(9), 1023-1035 (2013-06-06) Prostate Sphere-forming Stem Cells Are Derived from the P63-expressing Basal Compartment.Yanqing Huang et al.The Journal of biological chemistry, 290(29), 17745-17752 (2015-06-03) The role of Smad2 and Smad3 in regulating homeostatic functions of fibroblasts in vitro and in adult mice.Shuaibo Huang et al.Biochimica et biophysica acta. Molecular cell research, 1867(7), 118703-118703 (2020-03-18) Role of smooth muscle cell p53 in pulmonary arterial hypertension.Takayuki Wakasugi et al.PloS one, 14(2), e0212889-e0212889 (2019-02-27) Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).Zhichao Liu et al.PLoS computational biology, 7(12), e1002310-e1002310 (2011-12-24) Krüpple-like factor 5 is required for proper maintenance of adult intestinal crypt cellular proliferation.Kristin N Bell et al.Digestive diseases and sciences, 60(1), 86-100 (2014-07-30) TIGAR/AP-1 axis accelerates the division of Lgr5- reserve intestinal stem cells to reestablish intestinal architecture after lethal radiation.Fei Chen et al.Cell death & disease, 11(7), 501-501 (2020-07-08) Disruption of retinoblastoma protein expression in the intestinal epithelium impairs lipid absorption.Pamela M Choi et al.American journal of physiology. Gastrointestinal and liver physiology, 306(10), G909-G915 (2014-04-20) Raloxifene inhibits cloned Kv4.3 channels in an estrogen receptor-independent manner.Yun Ju Chae et al.Pflugers Archiv : European journal of physiology, 467(8), 1663-1676 (2014-09-19) The pheromone darcin drives a circuit for innate and reinforced behaviours.Ebru Demir et al.Nature, 578(7793), 137-141 (2020-01-31) Spatiotemporal structure of cell fate decisions in murine neural crest.Ruslan Soldatov et al.Science (New York, N.Y.), 364(6444) (2019-06-07) Protein Kinase C alpha is a marker for antiestrogen resistance and is involved in the growth of tamoxifen resistant human breast cancer cells.Lisa B Frankel et al.Breast cancer research and treatment, 104(2), 165-179 (2006-10-25) Lead optimization toward proof-of-concept tools for Huntington's disease within a 4-(1H-pyrazol-4-yl)pyrimidine class of pan-JNK inhibitors.John Wityak et al.Journal of medicinal chemistry, 58(7), 2967-2987 (2015-03-12) Etiology of craniofacial malformations in mouse models of blepharophimosis, ptosis and epicanthus inversus syndrome.Églantine Heude et al.Human molecular genetics, 24(6), 1670-1681 (2014-11-25) Phase III comparison of tamoxifen versus tamoxifen plus ovarian function suppression in premenopausal women with node-negative, hormone receptor-positive breast cancer (E-3193, INT-0142): a trial of the Eastern Cooperative Oncology Group.Amye J Tevaarwerk et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(35), 3948-3958 (2014-10-29) C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event.Zachary J Messenger et al.Cell death & disease, 9(11), 1054-1054 (2018-10-17) Re-evaluation of cytostatic therapies for meningiomas in vitro.Annette Wilisch-Neumann et al.Journal of cancer research and clinical oncology, 140(8), 1343-1352 (2014-05-13) Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits.Seonghee Jung et al.Autophagy, 16(3), 512-530 (2019-06-27) Identification of Key Genes and Candidated Pathways in Human Autosomal Dominant Polycystic Kidney Disease by Bioinformatics Analysis.Dongmei Liu et al.Kidney & blood pressure research, 44(4), 533-552 (2019-07-23) Cardiac-specific ablation of ARNT leads to lipotoxicity and cardiomyopathy.Rongxue Wu et al.The Journal of clinical investigation, 124(11), 4795-4806 (2014-10-21) Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities.Anna Yu-Szu Huang et al.Neuron, 106(6), 992-1008 (2020-04-23) SIRT2: tumour suppressor or tumour promoter in operable breast cancer?Liane M McGlynn et al.European journal of cancer (Oxford, England : 1990), 50(2), 290-301 (2013-11-05) Excitatory cholinergic responses in mouse colon intramuscular interstitial cells of Cajal are due to enhanced Ca2+ release via M3 receptor activation.Bernard T Drumm et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(8), 10073-10095 (2020-06-17) Estradiol affects extracellular leptin:adiponectin ratio in human breast tissue in vivo.Vivian Morad et al.The Journal of clinical endocrinology and metabolism, 99(9), 3460-3467 (2014-05-07) Sequencing methods and datasets to improve functional interpretation of sleeping beauty mutagenesis screens.Jesse D Riordan et al.BMC genomics, 15, 1150-1150 (2014-12-21) Chemokine Signaling Controls Integrity of Radial Glial Scaffold in Developing Spinal Cord and Consequential Proper Position of Boundary Cap Cells.Yan Zhu et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(24), 9211-9224 (2015-06-19) Tamoxifen represses alcohol-induced transcription of RNA polymerase III-dependent genes in breast cancer cells.Qian Zhong et al.Oncotarget, 5(23), 12410-12417 (2014-11-18) Deficiency of cardiac Acyl-CoA synthetase-1 induces diastolic dysfunction, but pathologic hypertrophy is reversed by rapamycin.David S Paul et al.Biochimica et biophysica acta, 1841(6), 880-887 (2014-03-19) High-Dimensional Single-Cell Cartography Reveals Novel Skeletal Muscle-Resident Cell Populations.Lorenzo Giordani et al.Molecular cell, 74(3), 609-621 (2019-03-30) Regulatory T cells require TCR signaling for their suppressive function.Amanda M Schmidt et al.Journal of immunology (Baltimore, Md. : 1950), 194(9), 4362-4370 (2015-03-31) Therapeutic advances in BIG3-PHB2 inhibition targeting the crosstalk between estrogen and growth factors in breast cancer.Tetsuro Yoshimaru et al.Cancer science, 106(5), 550-558 (2015-03-05) Precise spatial restriction of BMP signaling is essential for articular cartilage differentiation.Ayan Ray et al.Development (Cambridge, England), 142(6), 1169-1179 (2015-03-12) Loss of B-cell translocation gene 2 expression in estrogen receptor-positive breast cancer predicts tamoxifen resistance.Maiko Takahashi et al.Cancer science, 105(6), 675-682 (2014-04-05) Aberrant oligodendroglial-vascular interactions disrupt the blood-brain barrier, triggering CNS inflammation.Jianqin Niu et al.Nature neuroscience, 22(5), 709-718 (2019-04-17) Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy.M Swiderska-Syn et al.Gut, 63(8), 1333-1344 (2013-11-01) Pharmacokinetics of endoxifen and tamoxifen in female mice: implications for comparative in vivo activity studies.Joel M Reid et al.Cancer chemotherapy and pharmacology, 74(6), 1271-1278 (2014-10-17) Ascl1 Converts Dorsal Midbrain Astrocytes into Functional Neurons In Vivo.Yueguang Liu et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(25), 9336-9355 (2015-06-26) Survivin modulates genes with divergent molecular functions and regulates proliferation of hematopoietic stem cells through Evi-1.S Fukuda et al.Leukemia, 29(2), 433-440 (2014-06-07) Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis.Veronika Ramovs et al.Life science alliance, 3(7) (2020-05-20) Multiple roles for HOXA3 in regulating thymus and parathyroid differentiation and morphogenesis in mouse.Jena L Chojnowski et al.Development (Cambridge, England), 141(19), 3697-3708 (2014-09-25) Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium.Jun Li et al.Nucleic acids research, 48(6), 2880-2896 (2020-01-21) GILZ regulates Th17 responses and restrains IL-17-mediated skin inflammation.Sarah A Jones et al.Journal of autoimmunity, 61, 73-80 (2015-06-17) The timing of upper-layer neurogenesis is conferred by sequential derepression and negative feedback from deep-layer neurons.Kenichi Toma et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(39), 13259-13276 (2014-09-26) Effects of tamoxifen and aromatase inhibitors on breast tissue enhancement in dynamic contrast-enhanced breast MR imaging: a longitudinal intraindividual cohort study.Simone Schrading et al.Radiology, 271(1), 45-55 (2014-01-31) LuxR-dependent quorum sensing: computer aided discovery of new inhibitors structurally unrelated to N-acylhomoserine lactones.Laurent Soulère et al.Bioorganic & medicinal chemistry letters, 20(15), 4355-4358 (2010-07-10) Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways.Shan Wang et al.Molecular and cellular biology, 35(7), 1299-1313 (2015-01-15) Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine.Lotte Bruens et al.Cell reports, 32(3), 107937-107937 (2020-07-23) SMAD2 and p38 signaling pathways act in concert to determine XY primordial germ cell fate in mice.Quan Wu et al.Development (Cambridge, England), 142(3), 575-586 (2015-01-22) Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program.Sun-Mi Park et al.The Journal of clinical investigation, 125(3), 1286-1298 (2015-02-11) LGR5 in breast cancer and ductal carcinoma in situ: a diagnostic and prognostic biomarker and a therapeutic target.Catharina Hagerling et al.BMC cancer, 20(1), 542-542 (2020-06-12) YAP1 and TAZ negatively control bone angiogenesis by limiting hypoxia-inducible factor signaling in endothelial cells.Kishor K Sivaraj et al.eLife, 9 (2020-01-21) Tangential migration of neuronal precursors of glutamatergic neurons in the adult mammalian brain.Gerald J Sun et al.Proceedings of the National Academy of Sciences of the United States of America, 112(30), 9484-9489 (2015-07-15) Poorly soluble marketed drugs display solvation limited solubility.Christel A S Bergström et al.Journal of medicinal chemistry, 50(23), 5858-5862 (2007-10-13) Tumor heterogeneity confounds and illuminates: a case for Darwinian tumor evolution.Kornelia Polyak Nature medicine, 20(4), 344-346 (2014-04-09) Esm1 modulates endothelial tip cell behavior and vascular permeability by enhancing VEGF bioavailability.Rocha SF, Schiller M, Jing D, et al. Circulation Research, 115(6), 581-590 (2014) Synthesis and anti breast cancer activity of biphenyl based chalcones.Anindra Sharma et al.Bioorganic & medicinal chemistry, 18(13), 4711-4720 (2010-07-08) Theiler's virus infection provokes the overexpression of genes coding for the chemokine Ip10 (CXCL10) in SJL/J murine astrocytes, which can be inhibited by modulators of estrogen receptors.Nazario Rubio et al.Journal of neurovirology, 20(5), 485-495 (2014-07-24) Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance.Kari R Fischer et al.Nature, 527(7579), 472-476 (2015-11-13) Targeted excision of VCP R155H mutation by Cre-LoxP technology as a promising therapeutic strategy for valosin-containing protein disease.Angèle Nalbandian et al.Human gene therapy methods, 26(1), 13-24 (2014-12-30) Synthesis and biological activities of nucleoside-estradiol conjugates.Hasrat Ali et al.Bioorganic & medicinal chemistry letters, 16(2), 317-319 (2005-11-09) Integrin β1 controls VE-cadherin localization and blood vessel stability.Hiroyuki Yamamoto et al.Nature communications, 6, 6429-6429 (2015-03-11) Huntingtin-Associated Protein 1 in Mouse Hypothalamus Stabilizes Glucocorticoid Receptor in Stress Response.Xingxing Chen et al.Frontiers in cellular neuroscience, 14, 125-125 (2020-06-26) Exposure to the polyester PET precursor--terephthalic acid induces and perpetuates DNA damage-harboring non-malignant human breast cells.Maria Gloria Luciani-Torres et al.Carcinogenesis, 36(1), 168-176 (2014-11-21) Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life.Kyriel M Pineault et al.Nature communications, 10(1), 3168-3168 (2019-07-20) Survivin as a therapeutic target in Sonic hedgehog-driven medulloblastoma.S N Brun et al.Oncogene, 34(29), 3770-3779 (2014-09-23) Design, synthesis and bioevaluation of novel candidate selective estrogen receptor modulators.Yogesh Yadav et al.European journal of medicinal chemistry, 46(9), 3858-3866 (2011-06-18) The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo.Cedric Bressan et al.eLife, 9 (2020-09-29) The cochlear sensory epithelium derives from Wnt responsive cells in the dorsomedial otic cup.Alexander S Brown et al.Developmental biology, 399(1), 177-187 (2015-01-17) Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.Kyoung-In Cho et al.Cellular and molecular life sciences : CMLS, 76(17), 3407-3432 (2019-04-05) Inducible activation of ERK5 MAP kinase enhances adult neurogenesis in the olfactory bulb and improves olfactory function.Wenbin Wang et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(20), 7833-7849 (2015-05-23) Should radiotherapy be omitted in women age 70 years or older with early breast cancer?Orit Kaidar-Person et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(36), 4569-4569 (2013-11-06) Role of Glial Cell Line-Derived Neurotrophic Factor in the Maintenance of Adult Mesencephalic Catecholaminergic Neurons.Daniel Enterría-Morales et al.Movement disorders : official journal of the Movement Disorder Society, 35(4), 565-576 (2020-01-14) Development and survival of MYC-driven lymphomas require the MYC antagonist MNT to curb MYC-induced apoptosis.Hai Vu Nguyen et al.Blood, 135(13), 1019-1031 (2020-01-25) Distinct pathways regulated by RET and estrogen receptor in luminal breast cancer demonstrate the biological basis for combination therapy.Philip M Spanheimer et al.Annals of surgery, 259(4), 793-799 (2013-09-21) Reduced postnatal expression of cochlear Connexin26 induces hearing loss and affects the developmental status of pillar cells in a dose-dependent manner.Le Xie et al.Neurochemistry international, 128, 196-205 (2019-04-30) Nkx2.1-derived astrocytes and neurons together with Slit2 are indispensable for anterior commissure formation.Shilpi Minocha et al.Nature communications, 6, 6887-6887 (2015-04-24) Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1.Hanadie Yousef et al.Nature medicine, 25(6), 988-1000 (2019-05-16) UDP-glucuronosyltransferases and clinical drug-drug interactions.Tony K L Kiang et al.Pharmacology & therapeutics, 106(1), 97-132 (2005-03-23) Acute organ failure following the loss of anti-apoptotic cellular FLICE-inhibitory protein involves activation of innate immune receptors.N Gehrke et al.Cell death and differentiation, 22(5), 826-837 (2014-10-25) Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism.Iben Lundgaard et al.Nature communications, 6, 6807-6807 (2015-04-24) Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury.Elke Ydens et al.Nature neuroscience, 23(5), 676-689 (2020-04-15) Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation.Ann H Tang et al.The EMBO journal, 33(23), 2782-2797 (2014-10-16) Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA.Marissa A Scavuzzo et al.Cell reports, 25(13), 3811-3827 (2018-12-28) The Cation Channel TMEM63B Is an Osmosensor Required for Hearing.Han Du et al.Cell reports, 31(5), 107596-107596 (2020-05-07) Inhibition of mammalian target of rapamycin protects against reperfusion injury in diabetic heart through STAT3 signaling.Anindita Das et al.Basic research in cardiology, 110(3), 31-31 (2015-04-26) Loss of endothelial-ARNT in adult mice contributes to dampened circulating proangiogenic cells and delayed wound healing.Yu Han et al.Vascular medicine (London, England), 19(6), 429-441 (2014-11-16) Recurrent circuits within medial entorhinal cortex superficial layers support grid cell firing.Ipshita Zutshi et al.Nature communications, 9(1), 3701-3701 (2018-09-14) Cellular origin and response of flat epithelium in the vestibular end organs of mice to Atoh1 overexpression.Lu He et al.Hearing research, 391, 107953-107953 (2020-04-03) The TSPO-NOX1 axis controls phagocyte-triggered pathological angiogenesis in the eye.Anne Wolf et al.Nature communications, 11(1), 2709-2709 (2020-06-03) LRIG1 Regulates Ontogeny of Smooth Muscle-Derived Subsets of Interstitial Cells of Cajal in Mice.Jumpei Kondo et al.Gastroenterology, 149(2), 407-419 (2015-04-30) Axillary dissection versus no axillary dissection in older T1N0 breast cancer patients: 15-year results of trial and out-trial patients.G Martelli et al.European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 40(7), 805-812 (2014-04-29) A genetic system for tissue-specific inhibition of cell proliferation.Wenjuan Pu et al.Development (Cambridge, England), 147(4) (2020-01-29) Knockout of Wdr1 results in cardiac hypertrophy and impaired cardiac function in adult mouse heart.Xia Huang et al.Gene, 697, 40-47 (2019-02-23) Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.Bruno Costa-Silva et al.Nature cell biology, 17(6), 816-826 (2015-05-20) Functional differentiation of RAMP2 and RAMP3 in their regulation of the vascular system.Akihiro Yamauchi et al.Journal of molecular and cellular cardiology, 77, 73-85 (2014-09-30) Genetic analysis reveals an unexpected role of BMP7 in initiation of ureteric bud outgrowth in mouse embryos.Alexandre Gonçalves et al.PloS one, 6(4), e19370-e19370 (2011-05-10) Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch.Irene Maria Aspalter et al.Nature communications, 6, 7264-7264 (2015-06-18) The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development.Stefanie Giera et al.Nature communications, 6, 6121-6121 (2015-01-22) A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration.Yuki Matsushita et al.Nature communications, 11(1), 332-332 (2020-01-18) Activation of P-TEFb by cAMP-PKA signaling in autosomal dominant polycystic kidney disease.Yongzhan Sun et al.Science advances, 5(6), eaaw3593-eaaw3593 (2019-06-12) The biliary epithelium gives rise to liver progenitor cells.Daniel Rodrigo-Torres et al.Hepatology (Baltimore, Md.), 60(4), 1367-1377 (2014-04-05) The first knockin mouse model of episodic ataxia type 2.Samuel J Rose et al.Experimental neurology, 261, 553-562 (2014-08-12) Adrenergic Signaling in Muscularis Macrophages Limits Infection-Induced Neuronal Loss.Fanny Matheis et al.Cell, 180(1), 64-78 (2020-01-11) Nrf2 reduces allergic asthma in mice through enhanced airway epithelial cytoprotective function.Thomas E Sussan et al.American journal of physiology. Lung cellular and molecular physiology, 309(1), L27-L36 (2015-05-10) The Effects of Tamoxifen in Combination with Tranilast on CXCL12-CXCR4 Axis and Invasion in Breast Cancer Cell Lines.Sara Darakhshan et al.Iranian journal of pharmaceutical research : IJPR, 13(2), 683-693 (2014-09-23) Elevated serum magnesium lowers calcification propensity in Memo1-deficient mice.Matthias B Moor et al.PloS one, 15(7), e0236361-e0236361 (2020-07-25) Kindlin-2 deficiency induces fatal intestinal obstruction in mice.Xiaokun He et al.Theranostics, 10(14), 6182-6200 (2020-06-03) LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate.Yajing Gao et al.Gastroenterology, 158(5), 1389-1401 (2020-01-14) The transcription factor Foxg1 regulates telencephalic progenitor proliferation cell autonomously, in part by controlling Pax6 expression levels.Martine N Manuel et al.Neural development, 6, 9-9 (2011-03-23) Role of microtubules in extracellular release of poliovirus.Matthew P Taylor et al.Journal of virology, 83(13), 6599-6609 (2009-04-17) Cytotoxic and PTP1B inhibitory activities from Erythrina abyssinica.Phi Hung Nguyen et al.Bioorganic & medicinal chemistry letters, 19(23), 6745-6749 (2009-10-20) Acute tissue injury activates satellite cells and promotes sarcoma formation via the HGF/c-MET signaling pathway.David Van Mater et al.Cancer research, 75(3), 605-614 (2014-12-17) Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression.Jon D Larson et al.Cancer cell, 35(1), 140-155 (2019-01-01) Genetic Tracing Identifies Early Segregation of the Cardiomyocyte and Nonmyocyte Lineages.Yan Li et al.Circulation research, 125(3), 343-355 (2019-06-13) Gonadotropin-mediated chemoresistance: Delineation of molecular pathways and targets.Suchismita Sahoo et al.BMC cancer, 15, 931-931 (2015-11-27) Investigations of an inducible intact dystrophin gene excision system in cardiac and skeletal muscle in vivo.Addeli Bez Batti Angulski et al.Scientific reports, 10(1), 10967-10967 (2020-07-06) ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression.Feven Tameire et al.Nature cell biology, 21(7), 889-899 (2019-07-03) CYP2D6 genotype and tamoxifen response for breast cancer: a systematic review and meta-analysis.Danny W K Lum et al.PloS one, 8(10), e76648-e76648 (2013-10-08) Sources of all-trans retinal oxidation independent of the aldehyde dehydrogenase 1A isozymes exist in the postnatal testis†.My-Thanh Beedle et al.Biology of reproduction, 100(2), 547-560 (2018-09-25) KLF5 regulates the integrity and oncogenicity of intestinal stem cells.Takeo Nakaya et al.Cancer research, 74(10), 2882-2891 (2014-03-15) Individualization of tamoxifen treatment for breast carcinoma.L Binkhorst et al.Clinical pharmacology and therapeutics, 92(4), 431-433 (2012-08-23) Astroglial glutamate transporter deficiency increases synaptic excitability and leads to pathological repetitive behaviors in mice.Tomomi Aida et al.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(7), 1569-1579 (2015-02-11) Hypophosphatemic rickets accelerate chondrogenesis and cell trans-differentiation from TMJ chondrocytes into bone cells via a sharp increase in β-catenin.Hui Li et al.Bone, 131, 115151-115151 (2019-11-22) Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican.Courtney C Hong et al.The Journal of experimental medicine, 217(10) (2020-07-11) Tamoxifen-DNA adduct formation in monkey and human reproductive organs.Elena E Hernandez-Ramon et al.Carcinogenesis, 35(5), 1172-1176 (2014-02-07) Age-related oxidative stress confines damage-responsive Bmi1+ cells to perivascular regions in the murine adult heart.Diego Herrero et al.Redox biology, 22, 101156-101156 (2019-03-10) Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis.Sara Lovisa et al.Science signaling, 13(635) (2020-06-11) Limited Regeneration Potential with Minimal Epicardial Progenitor Conversions in the Neonatal Mouse Heart after Injury.Weibin Cai et al.Cell reports, 28(1), 190-201 (2019-07-04) QSAR-based permeability model for drug-like compounds.Rafael Gozalbes et al.Bioorganic & medicinal chemistry, 19(8), 2615-2624 (2011-04-05) Paroxetine approval.Suzanne M Mahon et al.The American journal of nursing, 114(1), 10-10 (2013-12-29) Mitochondrial Uncoupling Protein 2 Knock-out Promotes Mitophagy to Decrease Retinal Ganglion Cell Death in a Mouse Model of Glaucoma.Daniel T Hass et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(18), 3582-3596 (2019-03-01) Identification of ILK as a critical regulator of VEGFR3 signalling and lymphatic vascular growth.Sofia Urner et al.The EMBO journal, 38(2) (2018-12-07) 2-phenyl-1-[4-(2-piperidine-1-yl-ethoxy)benzyl]-1H-benzimidazoles as ligands for the estrogen receptor: synthesis and pharmacological evaluation.Sandra Dettmann et al.Bioorganic & medicinal chemistry, 18(14), 4905-4916 (2010-07-06) RDH10 function is necessary for spontaneous fetal mouth movement that facilitates palate shelf elevation.Regina M Friedl et al.Disease models & mechanisms, 12(7) (2019-07-14) The prostate basal cell (BC) heterogeneity and the p63-positive BC differentiation spectrum in mice.Dong-Kee Lee et al.International journal of biological sciences, 10(9), 1007-1017 (2014-09-12) AP-2β/KCTD1 Control Distal Nephron Differentiation and Protect against Renal Fibrosis.Alexander G Marneros Developmental cell, 54(3), 348-366 (2020-06-20) Targeting disseminated estrogen-receptor-positive breast cancer cells in bone marrow.Johanna M Buschhaus et al.Oncogene, 39(34), 5649-5662 (2020-07-18) Origin and Lineage Plasticity of Endogenous Lacrimal Gland Epithelial Stem/Progenitor Cells.Liana Basova et al.iScience, 23(6), 101230-101230 (2020-06-20) Cutting Edge: Transcription Factor BCL6 Is Required for the Generation, but Not Maintenance, of Memory CD8+ T Cells in Acute Viral Infection.Zhenyu Liu et al.Journal of immunology (Baltimore, Md. : 1950), 203(2), 323-327 (2019-06-09) Tamoxifen resistance: from bench to bedside.Marjolein Droog et al.European journal of pharmacology, 717(1-3), 47-57 (2013-04-03) Combination treatment of tamoxifen with risperidone in breast cancer.Wei-Lan Yeh et al.PloS one, 9(6), e98805-e98805 (2014-06-03) The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem cell niche function.Joan Isern et al.eLife, 3, e03696-e03696 (2014-09-26) Therapeutic targeting of BRCA1-mutated breast cancers with agents that activate DNA repair.Elizabeth Alli et al.Cancer research, 74(21), 6205-6215 (2014-09-14) Tonic inhibition of murine proximal colon is due to nitrergic suppression of Ca2+ signaling in interstitial cells of Cajal.Bernard T Drumm et al.Scientific reports, 9(1), 4402-4402 (2019-03-15) Suppressing TGFβ signaling in regenerating epithelia in an inflammatory microenvironment is sufficient to cause invasive intestinal cancer.Hiroko Oshima et al.Cancer research, 75(4), 766-776 (2015-02-18) Postoperative tamoxifen for ductal carcinoma in situ.Helen Staley et al.The Cochrane database of systematic reviews, 10, CD007847-CD007847 (2012-10-19) IGF-2 is necessary for retinoblastoma-mediated enhanced adaptation after small-bowel resection.Pamela M Choi et al.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 18(11), 1887-1893 (2014-07-09) Heterotypic cell-cell communication regulates glandular stem cell multipotency.Alessia Centonze et al.Nature, 584(7822), 608-613 (2020-08-28) Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping.Giovanni Di Liberto et al.Cell, 175(2), 458-471 (2018-09-04) Tamoxifen treatment causes early hepatic insulin resistance.Nora Klöting et al.Acta diabetologica, 57(4), 495-498 (2020-01-08) Neural Stem Cells Behave as a Functional Niche for the Maturation of Newborn Neurons through the Secretion of PTN.Changyong Tang et al.Neuron, 101(1), 32-44 (2018-12-01) Endoxifen is a new potent inhibitor of PKC: a potential therapeutic agent for bipolar disorder.Shoukath M Ali et al.Bioorganic & medicinal chemistry letters, 20(8), 2665-2667 (2010-03-17) Characterization of Krt19 CreERT allele for targeting the nucleus pulposus cells in the postnatal mouse intervertebral disc.Sarthak Mohanty et al.Journal of cellular physiology, 235(1), 128-140 (2019-06-13) EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation.Daniel Zingg et al.Cancer cell, 34(1), 69-84 (2018-07-17) Adult skeletal muscle deletion of Mitofusin 1 and 2 impedes exercise performance and training capacity.Margaret B Bell et al.Journal of applied physiology (Bethesda, Md. : 1985), 126(2), 341-353 (2018-09-28) Rax Homeoprotein Regulates Photoreceptor Cell Maturation and Survival in Association with Crx in the Postnatal Mouse Retina.Shoichi Irie et al.Molecular and cellular biology, 35(15), 2583-2596 (2015-05-20) Cell Lineage Tracing Identifies Hormone-Regulated and Wnt-Responsive Vaginal Epithelial Stem Cells.Ayesha Ali et al.Cell reports, 30(5), 1463-1477 (2020-02-06) Resident c-kit(+) cells in the heart are not cardiac stem cells.Nishat Sultana et al.Nature communications, 6, 8701-8701 (2015-10-31) Invasive Ductular Reaction Operates Hepatobiliary Junctions upon Hepatocellular Injury in Rodents and Humans.Laure-Alix Clerbaux et al.The American journal of pathology, 189(8), 1569-1581 (2019-05-21) β1-Integrin alters ependymal stem cell BMP receptor localization and attenuates astrogliosis after spinal cord injury.Hilary A North et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(9), 3725-3733 (2015-03-06) Impact of Sox9 dosage and Hes1-mediated Notch signaling in controlling the plasticity of adult pancreatic duct cells in mice.Shinichi Hosokawa et al.Scientific reports, 5, 8518-8518 (2015-02-18) Activity of the antiestrogenic cajanin stilbene acid towards breast cancer.Yujie Fu et al.The Journal of nutritional biochemistry, 26(11), 1273-1282 (2015-09-15) Dual functions for the ssDNA-binding protein RPA in meiotic recombination.Baolu Shi et al.PLoS genetics, 15(2), e1007952-e1007952 (2019-02-05) Cancer-associated fibroblasts downregulate type I interferon receptor to stimulate intratumoral stromagenesis.Christina Cho et al.Oncogene, 39(38), 6129-6137 (2020-08-19) Ins1(Cre) knock-in mice for beta cell-specific gene recombination.Bernard Thorens et al.Diabetologia, 58(3), 558-565 (2014-12-17) D538G mutation in estrogen receptor-α: A novel mechanism for acquired endocrine resistance in breast cancer.Keren Merenbakh-Lamin et al.Cancer research, 73(23), 6856-6864 (2013-11-13) Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth.Francesca Zanconato et al.Nature cell biology, 17(9), 1218-1227 (2015-08-11) Endothelial alpha-parvin controls integrity of developing vasculature and is required for maintenance of cell-cell junctions.Alessia Fraccaroli et al.Circulation research, 117(1), 29-40 (2015-05-01) A mouse model of Townes-Brocks syndrome expressing a truncated mutant Sall1 protein is protected from acute kidney injury.Sara Hirsch et al.American journal of physiology. Renal physiology, 309(10), F852-F863 (2015-08-28) A Widespread Neurogenic Potential of Neocortical Astrocytes Is Induced by Injury.Margherita Zamboni et al.Cell stem cell, 27(4), 605-617 (2020-08-08) A Murine Myh6MerCreMer Knock-In Allele Specifically Mediates Temporal Genetic Deletion in Cardiomyocytes after Tamoxifen Induction.Jianyun Yan et al.PloS one, 10(7), e0133472-e0133472 (2015-07-24) Tamoxifen for the management of breast events induced by non-steroidal antiandrogens in patients with prostate cancer: a systematic review.Frank Kunath et al.BMC medicine, 10, 96-96 (2012-08-29) Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1.You-Ying Chau et al.PLoS genetics, 7(12), e1002404-e1002404 (2012-01-05) Gynaecomastia surgery in the Netherlands: what, why, who, where….Oren Lapid et al.Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 67(5), 702-706 (2014-03-08) Generation of a Tph2 Conditional Knockout Mouse Line for Time- and Tissue-Specific Depletion of Brain Serotonin.Barbara Pelosi et al.PloS one, 10(8), e0136422-e0136422 (2015-08-21) Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors.Kamryn N Gerner-Mauro et al.Proceedings of the National Academy of Sciences of the United States of America, 117(22), 12182-12191 (2020-05-18) Focal adhesion kinase is required for synovial fibroblast invasion, but not murine inflammatory arthritis.Miriam A Shelef et al.Arthritis research & therapy, 16(5), 464-464 (2014-10-05) Mice depleted of the coxsackievirus and adenovirus receptor display normal spermatogenesis and an intact blood-testis barrier.Taranum Sultana et al.Reproduction (Cambridge, England), 147(6), 875-883 (2014-03-15) Colonic CD90+ Crypt Fibroblasts Secrete Semaphorins to Support Epithelial Growth.Olga N Karpus et al.Cell reports, 26(13), 3698-3708 (2019-03-28) New potent imidazoisoquinolinone derivatives as anti-Trypanosoma cruzi agents: biological evaluation and structure-activity relationships.Mariela Bollini et al.Bioorganic & medicinal chemistry, 17(4), 1437-1444 (2009-01-27) Optimizing tamoxifen-inducible Cre/loxp system to reduce tamoxifen effect on bone turnover in long bones of young mice.Zhendong A Zhong et al.Bone, 81, 614-619 (2015-08-02) Polycystin-1 Regulates Actomyosin Contraction and the Cellular Response to Extracellular Stiffness.Elisa Agnese Nigro et al.Scientific reports, 9(1), 16640-16640 (2019-11-14) ING5 is phosphorylated by CDK2 and controls cell proliferation independently of p53.Ulrike Linzen et al.PloS one, 10(4), e0123736-e0123736 (2015-04-11) Characterization of perinatally born glutamatergic neurons of the mouse olfactory bulb based on NeuroD6 expression reveals their resistance to sensory deprivation.Alexandra Angelova et al.The Journal of comparative neurology, 527(7), 1245-1260 (2018-12-29) Arf1-mediated lipid metabolism sustains cancer cells and its ablation induces anti-tumor immune responses in mice.Guohao Wang et al.Nature communications, 11(1), 220-220 (2020-01-12) Low doses of decitabine improve the chemotherapy efficacy against basal-like bladder cancer by targeting cancer stem cells.Mingqing Wu et al.Oncogene, 38(27), 5425-5439 (2019-03-29) Uterine sarcoma after tamoxifen therapy for breast cancer.Mat Samuji et al.Irish medical journal, 106(8), 246-246 (2013-11-29) Intact neuronal function in Rheb1 mutant mice: implications for TORC1-based treatments.Susanna M I Goorden et al.Human molecular genetics, 24(12), 3390-3398 (2015-03-12) Cell type composition and circuit organization of clonally related excitatory neurons in the juvenile mouse neocortex.Cathryn R Cadwell et al.eLife, 9 (2020-03-07) Wnt-responsive Lgr5⁺ globose basal cells function as multipotent olfactory epithelium progenitor cells.Mengfei Chen et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(24), 8268-8276 (2014-06-13) Somatic activating mutations in PIK3CA cause generalized lymphatic anomaly.Lara Rodriguez-Laguna et al.The Journal of experimental medicine, 216(2), 407-418 (2018-12-29) RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock.Constantinos M Mikelis et al.Nature communications, 6, 6725-6725 (2015-04-11) LSD1 Cooperates with Noncanonical NF-κB Signaling to Regulate Marginal Zone B Cell Development.Robert R Haines et al.Journal of immunology (Baltimore, Md. : 1950), 203(7), 1867-1881 (2019-09-08) ObRb downregulation increases breast cancer cell sensitivity to tamoxifen.Yingying Qian et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 36(9), 6813-6821 (2015-04-08) Evidence of Progenitor Cell Lineage Rerouting in the Adult Mouse Hippocampus After Status Epilepticus.Daniela M S Moura et al.Frontiers in neuroscience, 14, 571315-571315 (2020-10-20) Androgen receptor expression in male breast cancer predicts inferior outcome and poor response to tamoxifen treatment.Zhao Wenhui et al.European journal of endocrinology, 171(4), 527-533 (2014-07-30) ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2.Jan P Weber et al.The Journal of experimental medicine, 212(2), 217-233 (2015-02-04) The transcriptional landscape of lncRNAs reveals the oncogenic function of LINC00511 in ER-negative breast cancer.Jian Zhang et al.Cell death & disease, 10(8), 599-599 (2019-08-10) Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes.Rodrigo Diéguez-Hurtado et al.Nature communications, 10(1), 2817-2817 (2019-06-30) Mutant huntingtin reduction in astrocytes slows disease progression in the BACHD conditional Huntington's disease mouse model.Tara E Wood et al.Human molecular genetics, 28(3), 487-500 (2018-10-13) ABL kinase inhibition promotes lung regeneration through expansion of an SCGB1A1+ SPC+ cell population following bacterial pneumonia.Aaditya Khatri et al.Proceedings of the National Academy of Sciences of the United States of America, 116(5), 1603-1612 (2019-01-19) P2Y₂ and Gq/G₁₁ control blood pressure by mediating endothelial mechanotransduction.ShengPeng Wang et al.The Journal of clinical investigation, 125(8), 3077-3086 (2015-07-15) Pacemaker function and neural responsiveness of subserosal interstitial cells of Cajal in the mouse colon.Bernard T Drumm et al.The Journal of physiology, 598(4), 651-681 (2019-12-08) Roles for Nkx2-5 and Gata3 in the ontogeny of the murine smooth muscle gastric ligaments.Ajay Prakash et al.American journal of physiology. Gastrointestinal and liver physiology, 307(4), G430-G436 (2014-06-28) Schistosoma haematobium egg-induced bladder urothelial abnormalities dependent on p53 are modulated by host sex.Jared Honeycutt et al.Experimental parasitology, 158, 55-60 (2015-07-15) Olig2 SUMOylation protects against genotoxic damage response by antagonizing p53 gene targeting.Huiqing Liu et al.Cell death and differentiation, 27(11), 3146-3161 (2020-06-03) Estrogen receptor antagonism uncovers gender-dimorphic suppression of whole body fat oxidation in humans: differential effects of tamoxifen on the GH and gonadal axes.Vita Birzniece et al.European journal of endocrinology, 173(4), 479-487 (2015-07-23) Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.Johannes Kornhuber et al.Journal of medicinal chemistry, 51(2), 219-237 (2007-11-22) A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate.Wenshan Wang et al.Cell metabolism, 30(1), 174-189 (2019-06-04) Transcription Factor PROX1 Suppresses Notch Pathway Activation via the Nucleosome Remodeling and Deacetylase Complex in Colorectal Cancer Stem-like Cells.Jenny Högström et al.Cancer research, 78(20), 5820-5832 (2018-08-30) Selective estrogen-receptor modulators suppress microglial activation and neuronal cell death via an estrogen receptor-dependent pathway.Yasuhiro Ishihara et al.The Journal of steroid biochemistry and molecular biology, 145, 85-93 (2014-10-12) The endogenous molecular clock orchestrates the temporal separation of substrate metabolism in skeletal muscle.Brian A Hodge et al.Skeletal muscle, 5, 17-17 (2015-05-23) Combination of cyclopamine and tamoxifen promotes survival and migration of mcf-7 breast cancer cells--interaction of hedgehog-gli and estrogen receptor signaling pathways.Maja Sabol et al.PloS one, 9(12), e114510-e114510 (2014-12-17) Mechanisms of tamoxifen-induced apoptosis.S Mandlekar et al.Apoptosis : an international journal on programmed cell death, 6(6), 469-477 (2001-10-12) Hippocampal neural stem cells facilitate access from circulation via apical cytoplasmic processes.Tamar Licht et al.eLife, 9 (2020-06-05) Inducible reduction in pregnancy-associated plasma protein-A gene expression inhibits established atherosclerotic plaque progression in mice.Laurie K Bale et al.Endocrinology, 155(4), 1184-1187 (2014-02-11) The Stem Cell Factor Sox2 Is a Positive Timer of Oligodendrocyte Development in the Postnatal Murine Spinal Cord.Sheng Zhang et al.Molecular neurobiology, 55(12), 9001-9015 (2018-04-07) Alteration in Nuclear Factor-KappaB Pathway and Functionality of Estrogen via Receptors Promote Neuroinflammation in Frontal Cortex after 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Treatment.Soham Mitra et al.Scientific reports, 5, 13949-13949 (2015-09-15) Stromal β-catenin activation impacts nephron progenitor differentiation in the developing kidney and may contribute to Wilms tumor.Keri A Drake et al.Development (Cambridge, England), 147(21) (2020-06-17) WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited.Luke Boulter et al.The Journal of clinical investigation, 125(3), 1269-1285 (2015-02-18) Higher estimated net endogenous Acid production may be associated with increased prevalence of nonalcoholic Fatty liver disease in chinese adults in Hong Kong.Ruth Chan et al.PloS one, 10(4), e0122406-e0122406 (2015-04-24) Using the pER8:GUS reporter system to screen for phytoestrogens from Caesalpinia sappan.Wan-Chun Lai et al.Journal of natural products, 74(8), 1698-1706 (2011-08-02) Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways.Sheng Zhang et al.Nature communications, 11(1), 2027-2027 (2020-04-26) The combination of methylsulfonylmethane and tamoxifen inhibits the Jak2/STAT5b pathway and synergistically inhibits tumor growth and metastasis in ER-positive breast cancer xenografts.Nipin S P et al.BMC cancer, 15, 474-474 (2015-06-19) Growth Plate Borderline Chondrocytes Behave as Transient Mesenchymal Precursor Cells.Koji Mizuhashi et al.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 34(8), 1387-1392 (2019-03-20) Astrocyte-specific deletion of the mitochondrial m-AAA protease reveals glial contribution to neurodegeneration.Sara Murru et al.Glia, 67(8), 1526-1541 (2019-04-17) MafA is critical for maintenance of the mature beta cell phenotype in mice.Wataru Nishimura et al.Diabetologia, 58(3), 566-574 (2014-12-17) Central nervous system regeneration is driven by microglia necroptosis and repopulation.Amy F Lloyd et al.Nature neuroscience, 22(7), 1046-1052 (2019-06-12) Tamoxifen augments the innate immune function of neutrophils through modulation of intracellular ceramide.Ross Corriden et al.Nature communications, 6, 8369-8369 (2015-10-16) Seven In Absentia Homolog 2 (SIAH2) downregulation is associated with tamoxifen resistance in MCF-7 breast cancer cells.Interiano RB, Yang J, Harris AL, et al. The Journal of Surgical Research, 190(1), 203-209 (2014) ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A.Sarah J Hatsell et al.Science translational medicine, 7(303), 303ra137-303ra137 (2015-09-04) Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis.Nobuyuki Kakiuchi et al.Nature, 577(7789), 260-265 (2019-12-20) EED-mediated histone methylation is critical for CNS myelination and remyelination by inhibiting WNT, BMP, and senescence pathways.Jiajia Wang et al.Science advances, 6(33), eaaz6477-eaaz6477 (2020-08-28) Radiotherapy options after breast-conserving surgery: how can selection of patients be refined?Pelagia G Tsoutsou et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(36), 4570-4571 (2013-11-06) A dual genetic tracing system identifies diverse and dynamic origins of cardiac valve mesenchyme.Kuo Liu et al.Development (Cambridge, England), 145(18) (2018-08-17) G protein-coupled estrogen receptor regulates mammary tumorigenesis and metastasis.Nicole A Marjon et al.Molecular cancer research : MCR, 12(11), 1644-1654 (2014-07-18) Genomic interaction between ER and HMGB2 identifies DDX18 as a novel driver of endocrine resistance in breast cancer cells.A M Redmond et al.Oncogene, 34(29), 3871-3880 (2014-10-07) PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination.Ana Mendanha Falcão et al.Cell reports, 27(4), 1090-1102 (2019-04-25) Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia.Yue J Wang et al.PloS one, 9(11), e113127-e113127 (2014-11-19) Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis.Rafael Kramann et al.The Journal of clinical investigation, 125(8), 2935-2951 (2015-07-21) Exemestane with ovarian suppression in premenopausal breast cancer.Vito Amoroso et al.The New England journal of medicine, 371(14), 1357-1357 (2014-10-02) The generation of superficial cortical layers is regulated by levels of the transcription factor Pax6.Petrina A Georgala et al.Cerebral cortex (New York, N.Y. : 1991), 21(1), 81-94 (2010-04-24) Fate mapping reveals origin and dynamics of lymph node follicular dendritic cells.Meryem Jarjour et al.The Journal of experimental medicine, 211(6), 1109-1122 (2014-05-28) Fibroblast-Specific Deletion of Hypoxia Inducible Factor-1 Critically Impairs Murine Cutaneous Neovascularization and Wound Healing.Dominik Duscher et al.Plastic and reconstructive surgery, 136(5), 1004-1013 (2015-10-28) A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate.Phillip T Newton et al.Nature, 567(7747), 234-238 (2019-03-01) Adult neural precursor cells from the subventricular zone contribute significantly to oligodendrocyte regeneration and remyelination.Yao Lulu Xing et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(42), 14128-14146 (2014-10-17) Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells.Jin Li et al.Nature communications, 6, 6804-6804 (2015-04-22) mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo.Dàlia Raïch-Regué et al.Journal of immunology (Baltimore, Md. : 1950), 194(10), 4767-4776 (2015-04-05) Tamoxifen-independent recombination in the RIP-CreER mouse.Yanmei Liu et al.PloS one, 5(10), e13533-e13533 (2010-11-11) Experimental Traumatic Brain Injury Identifies Distinct Early and Late Phase Axonal Conduction Deficits of White Matter Pathophysiology, and Reveals Intervening Recovery.Christina M Marion et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(41), 8723-8736 (2018-08-26) Limitations of In Vivo Reprogramming to Dopaminergic Neurons via a Tricistronic Strategy.Marina Theodorou et al.Human gene therapy methods, 26(4), 107-122 (2015-06-25) Fibroblast-specific upregulation of Flightless I impairs wound healing.Christopher T Turner et al.Experimental dermatology, 24(9), 692-697 (2015-05-12) Inhibition of herpes simplex virus type 1 entry by chloride channel inhibitors tamoxifen and NPPB.Kai Zheng et al.Biochemical and biophysical research communications, 446(4), 990-996 (2014-03-25) Camouflaged, activatable and therapeutic tandem bionanoreactors for breast cancer theranosis.Kanchan Chauhan et al.Journal of colloid and interface science, 580, 365-376 (2020-07-21) Syk tyrosine kinase is critical for B cell antibody responses and memory B cell survival.Jochen A Ackermann et al.Journal of immunology (Baltimore, Md. : 1950), 194(10), 4650-4656 (2015-04-12) A kinase inhibitor screen identifies Mcl-1 and Aurora kinase A as novel treatment targets in antiestrogen-resistant breast cancer cells.S Thrane et al.Oncogene, 34(32), 4199-4210 (2014-11-05) Loss of CARD9-mediated innate activation attenuates severe influenza pneumonia without compromising host viral immunity.Takayuki Uematsu et al.Scientific reports, 5, 17577-17577 (2015-12-03) Down-regulation of MSH2 expression by Hsp90 inhibition enhances cytotoxicity affected by tamoxifen in human lung cancer cells.Jen-Chung Ko et al.Biochemical and biophysical research communications, 456(1), 506-512 (2014-12-10) Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri.Wenxu Zhou et al.PLoS pathogens, 14(9), e1007245-e1007245 (2018-09-14) Yap and its subcellular localization have distinct compartment-specific roles in the developing lung.Benjamin J van Soldt et al.Development (Cambridge, England), 146(9) (2019-04-05) Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling.Eman Khatib-Massalha et al.Nature communications, 11(1), 3547-3547 (2020-07-17) Lgr5+ cells regenerate hair cells via proliferation and direct transdifferentiation in damaged neonatal mouse utricle.Tian Wang et al.Nature communications, 6, 6613-6613 (2015-04-08) No effect on pharmacokinetics of tamoxifen and 4-hydroxytamoxifen by multiple doses of red clover capsule in rats.Kanumuri Siva Rama Raju et al.Scientific reports, 5, 16126-16126 (2015-11-05) Feature-selective encoding of substrate vibrations in the forelimb somatosensory cortex.Mario Prsa et al.Nature, 567(7748), 384-388 (2019-03-15) JunB Controls Intestinal Effector Programs in Regulatory T Cells.Joshua D Wheaton et al.Frontiers in immunology, 11, 444-444 (2020-04-17) Loss of serum response factor in mature neurons in the dentate gyrus alters the morphology of dendritic spines and hippocampus-dependent behavioral tasks.Karolina Nader et al.Brain structure & function, 224(8), 2691-2701 (2019-08-04) Thymine DNA glycosylase as a novel target for melanoma.Pietro Mancuso et al.Oncogene, 38(19), 3710-3728 (2019-01-25) Defining multistep cell fate decision pathways during pancreatic development at single-cell resolution.Xin-Xin Yu et al.The EMBO journal, 38(8) (2019-02-10) ADAM17 promotes proliferation of collecting duct kidney epithelial cells through ERK activation and increased glycolysis in polycystic kidney disease.Monika Beck Gooz et al.American journal of physiology. Renal physiology, 307(5), F551-F559 (2014-06-06) Conditional ablation of p63 indicates that it is essential for embryonic development of the central nervous system.Gonzalo I Cancino et al.Cell cycle (Georgetown, Tex.), 14(20), 3270-3281 (2015-09-12) Dominant role of interstitial cells of Cajal in nitrergic relaxation of murine lower oesophageal sphincter.Dieter Groneberg et al.The Journal of physiology, 593(2), 403-414 (2015-01-30) Lineage specification of ovarian theca cells requires multicellular interactions via oocyte and granulosa cells.Chang Liu et al.Nature communications, 6, 6934-6934 (2015-04-29) Cell-Type-Specific Gene Inactivation and In Situ Restoration via Recombinase-Based Flipping of Targeted Genomic Region.Xue Liu et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(37), 7169-7186 (2020-08-18) Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).Jenny M Pedersen et al.Journal of medicinal chemistry, 51(11), 3275-3287 (2008-05-07) Complement C1q-induced activation of β-catenin signalling causes hypertensive arterial remodelling.Tomokazu Sumida et al.Nature communications, 6, 6241-6241 (2015-02-27) Targeting ceramide metabolic pathway induces apoptosis in human breast cancer cell lines.Helen Shiphrah Vethakanraj et al.Biochemical and biophysical research communications, 464(3), 833-839 (2015-07-19) USP9X downregulation renders breast cancer cells resistant to tamoxifen.Hendrika M Oosterkamp et al.Cancer research, 74(14), 3810-3820 (2014-07-17) The Japanese toxicogenomics project: application of toxicogenomics.Takeki Uehara et al.Molecular nutrition & food research, 54(2), 218-227 (2009-12-31) PIK3CA mutations, phosphatase and tensin homolog, human epidermal growth factor receptor 2, and insulin-like growth factor 1 receptor and adjuvant tamoxifen resistance in postmenopausal breast cancer patients.Karin Beelen et al.Breast cancer research : BCR, 16(1), R13-R13 (2014-01-29) [Rare cause for severe hypertriglyceridemia - case 9/2013].Sabine Kahl et al.Deutsche medizinische Wochenschrift (1946), 138(47), 2410-2410 (2013-11-14) mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse.D Thumkeo et al.Science advances, 6(1), eaay2432-eaay2432 (2020-01-09) Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells.Jennifer Y Tan et al.Genome research, 25(5), 655-666 (2015-03-21) Hes1 attenuates type I IFN responses via VEGF-C and WDFY1.Fei Ning et al.The Journal of experimental medicine, 216(6), 1396-1410 (2019-04-25) Hhex regulates Kit to promote radioresistance of self-renewing thymocytes in Lmo2-transgenic mice.B J Shields et al.Leukemia, 29(4), 927-938 (2014-10-07) Fetal origin confers radioresistance on liver macrophages via p21cip1/WAF1.Radika Soysa et al.Journal of hepatology, 71(3), 553-562 (2019-05-12) Temozolomide increases the number of mismatch repair-deficient intestinal crypts and accelerates tumorigenesis in a mouse model of Lynch syndrome.Kamila Wojciechowicz et al.Gastroenterology, 147(5), 1064-1072 (2014-08-05) Reduced Activity of Sphingosine-1-Phosphate Lyase Induces Podocyte-related Glomerular Proteinuria, Skin Irritation, and Platelet Activation.Jens Schümann et al.Toxicologic pathology, 43(5), 694-703 (2015-01-30) CDC42 inhibition suppresses progression of incipient intestinal tumors.Sakamori R, Yu S, Zhang X, et al. Cancer Research, 74(19), 5480-5492 (2014) Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain.Chaitali Mukherjee et al.Cell metabolism, 32(2), 259-272 (2020-06-13) Development of migrating tendon-bone attachments involves replacement of progenitor populations.Neta Felsenthal et al.Development (Cambridge, England), 145(24) (2018-12-07) The active contribution of OPCs to neuroinflammation is mediated by LRP1.Anthony Fernández-Castañeda et al.Acta neuropathologica, 139(2), 365-382 (2019-09-26) Reversible changes in pancreatic islet structure and function produced by elevated blood glucose.Melissa F Brereton et al.Nature communications, 5, 4639-4639 (2014-08-26) Na+/Ca2 + Exchange and Pacemaker Activity of Interstitial Cells of Cajal.Haifeng Zheng et al.Frontiers in physiology, 11, 230-230 (2020-04-08) Temporospatial distribution and transcriptional profile of retinal microglia in the oxygen-induced retinopathy mouse model.Myriam Boeck et al.Glia, 68(9), 1859-1873 (2020-03-10) Wnts are dispensable for differentiation and self-renewal of adult murine hematopoietic stem cells.Zahra Kabiri et al.Blood, 126(9), 1086-1094 (2015-06-20) Direct acute tubular damage contributes to Shigatoxin-mediated kidney failure.Stefan Porubsky et al.The Journal of pathology, 234(1), 120-133 (2014-06-10) Retrograde migration supplies resident memory T cells to lung-draining LN after influenza infection.J Michael Stolley et al.The Journal of experimental medicine, 217(8) (2020-06-23) The role of endothelial MERTK during the inflammatory response in lungs.Yitong Li et al.PloS one, 14(12), e0225051-e0225051 (2019-12-06) Microglial Function Is Distinct in Different Anatomical Locations during Retinal Homeostasis and Degeneration.Emily G O'Koren et al.Immunity, 50(3), 723-737 (2019-03-10) Small molecule regulators of autophagy identified by an image-based high-throughput screen.Lihong Zhang et al.Proceedings of the National Academy of Sciences of the United States of America, 104(48), 19023-19028 (2007-11-21) Silencing of TGFβ signalling in microglia results in impaired homeostasis.Tanja Zöller et al.Nature communications, 9(1), 4011-4011 (2018-10-03) Highly Combinatorial Genetic Interaction Analysis Reveals a Multi-Drug Transporter Influence Network.Albi Celaj et al.Cell systems, 10(1), 25-38 (2019-11-02) Adjuvant ovarian suppression in premenopausal breast cancer.Prudence A Francis et al.The New England journal of medicine, 372(5), 436-446 (2014-12-17) Conditional Knock-out of mGluR5 from Astrocytes during Epilepsy Development Impairs High-Frequency Glutamate Uptake.Anthony D Umpierre et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(4), 727-742 (2018-12-07) Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis.Eugenio Sangiorgi et al.Proceedings of the National Academy of Sciences of the United States of America, 106(17), 7101-7106 (2009-04-18) TRIM67 Activates p53 to Suppress Colorectal Cancer Initiation and Progression.Shiyan Wang et al.Cancer research, 79(16), 4086-4098 (2019-06-27) The role of follicular helper T cells and the germinal center in HIV-1 gp120 DNA prime and gp120 protein boost vaccination.Kristin Hollister et al.Human vaccines & immunotherapeutics, 10(7), 1985-1992 (2014-11-27) Apj+ Vessels Drive Tumor Growth and Represent a Tractable Therapeutic Target.Huan Zhao et al.Cell reports, 25(5), 1241-1254 (2018-11-01) c-MAF deletion in adult C57BL/6J mice induces cataract formation and abnormal differentiation of lens fiber cells.Mitsunori Fujino et al.Experimental animals, 69(2), 242-249 (2020-01-24) Omega-3 free fatty acids inhibit tamoxifen-induced cell apoptosis.Shufan Wu et al.Biochemical and biophysical research communications, 459(2), 294-299 (2015-03-03) SIRT1 Protects the Heart from ER Stress-Induced Injury by Promoting eEF2K/eEF2-Dependent Autophagy.Julie Pires Da Silva et al.Cells, 9(2) (2020-02-16) The EIIIA domain from astrocyte-derived fibronectin mediates proliferation of oligodendrocyte progenitor cells following CNS demyelination.Josephine M J Stoffels et al.Glia, 63(2), 242-256 (2014-08-27) The Chemopreventive Effect of Tanacetum Polycephalum Against LA7-Induced Breast Cancer in Rats and the Apoptotic Effect of a Cytotoxic Sesquiterpene Lactone in MCF7 Cells: A Bioassay-Guided Approach.Hamed Karimian et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 36(3), 988-1003 (2015-06-20) Lineage tracing of axial progenitors using Nkx1-2CreERT2 mice defines their trunk and tail contributions.Aida Rodrigo Albors et al.Development (Cambridge, England), 145(19) (2018-09-12) Sirt1 deletion leads to enhanced inflammation and aggravates endotoxin-induced acute kidney injury.Rong Gao et al.PloS one, 9(6), e98909-e98909 (2014-06-05) BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors.Hyun Yong Koh et al.Nature medicine, 24(11), 1662-1668 (2018-09-19) Development of Ependymal and Postnatal Neural Stem Cells and Their Origin from a Common Embryonic Progenitor.Stephanie A Redmond et al.Cell reports, 27(2), 429-441 (2019-04-11) Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory.Fei Wang et al.Nature neuroscience, 23(4), 481-486 (2020-02-12) 3-D tumor model for in vitro evaluation of anticancer drugs.Jayme L Horning et al.Molecular pharmaceutics, 5(5), 849-862 (2008-08-06) Juvenile mild traumatic brain injury elicits distinct spatiotemporal astrocyte responses.Tifenn Clément et al.Glia, 68(3), 528-542 (2019-11-02) High-dosage tamoxifen as neoadjuvant treatment in minimally invasive surgery for Dupuytren disease in patients with a strong predisposition toward fibrosis: a randomized controlled trial.Ilse Degreef et al.The Journal of bone and joint surgery. American volume, 96(8), 655-662 (2014-04-18) Intracellular Role for the Matrix-Modifying Enzyme Lox in Regulating Transcription Factor Subcellular Localization and Activity in Muscle Regeneration.Ravit Gabay Yehezkely et al.Developmental cell, 53(4), 406-417 (2020-05-04) Memory B cells contribute to rapid Bcl6 expression by memory follicular helper T cells.Wataru Ise et al.Proceedings of the National Academy of Sciences of the United States of America, 111(32), 11792-11797 (2014-07-30) Sox2, Tlx, Gli3, and Her9 converge on Rx2 to define retinal stem cells in vivo.Robert Reinhardt et al.The EMBO journal, 34(11), 1572-1588 (2015-04-25) Summaries for patients. Using medications to decrease the risk for breast cancer in women: recommendations from the U.S. Preventive Services Task Force. Annals of internal medicine, 159(10), I-28 (2014-01-09) Estrogen prevents high-glucose-induced damage of retinal ganglion cells via mitochondrial pathway.Ming Hao et al.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 253(1), 83-90 (2014-09-14) Myofibroblastic Conversion and Regeneration of Mesothelial Cells in Peritoneal and Liver Fibrosis.Ingrid Lua et al.The American journal of pathology, 185(12), 3258-3273 (2015-11-26) Evaluation of the pharmacological activities of RAD1901, a selective estrogen receptor degrader.Suzanne E Wardell et al.Endocrine-related cancer, 22(5), 713-724 (2015-07-15) A mutant selective anti-estrogen is a pure antagonist on EREs and AP-1 response elements.Disha Jain et al.Bioorganic & medicinal chemistry letters, 20(17), 5258-5261 (2010-07-28) The anticancer agent di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes prosurvival autophagy by two mechanisms: persistent induction of autophagosome synthesis and impairment of lysosomal integrity.Elaine Gutierrez et al.The Journal of biological chemistry, 289(48), 33568-33589 (2014-10-11) Impact of mTOR hyperactive neurons on the morphology and physiology of adjacent neurons: Do PTEN KO cells make bad neighbors?Candi L LaSarge et al.Experimental neurology, 321, 113029-113029 (2019-08-05) Exemestane with ovarian suppression in premenopausal breast cancer.Rowan T Chlebowski et al.The New England journal of medicine, 371(14), 1358-1358 (2014-10-02) The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth.Claudia Bossen et al.Nature immunology, 16(7), 775-784 (2015-05-20) Critical roles for nitric oxide and ERK in the completion of prosurvival autophagy in 4OHTAM-treated estrogen receptor-positive breast cancer cells.Lei Duan et al.Cancer letters, 353(2), 290-300 (2014-07-30) Autocrine action of BDNF on dendrite development of adult-born hippocampal neurons.Liang Wang et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(22), 8384-8393 (2015-06-05) GATA-3 dose-dependent checkpoints in early T cell commitment.Deirdre D Scripture-Adams et al.Journal of immunology (Baltimore, Md. : 1950), 193(7), 3470-3491 (2014-08-31) Single Eye mRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation.Oliver H Bell et al.Frontiers in immunology, 10, 3033-3033 (2020-01-30) Potential therapeutic benefit of combining gefitinib and tamoxifen for treating advanced lung adenocarcinoma.Chien-Ming Liu et al.BioMed research international, 2015, 642041-642041 (2015-02-19) Increased COX-2 expression in epithelial and stromal cells of high mammographic density tissues and in a xenograft model of mammographic density.G L Chew et al.Breast cancer research and treatment, 153(1), 89-99 (2015-08-01) Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration.Lian Zhao et al.EMBO molecular medicine, 7(9), 1179-1197 (2015-07-04) Delivery of Glucosylceramidase Beta Gene Using AAV9 Vector Therapy as a Treatment Strategy in Mouse Models of Gaucher Disease.Sichen Du et al.Human gene therapy, 30(2), 155-167 (2018-08-21) Kaiyue Zhang et al.The Journal of biological chemistry, 295(34), 12203-12213 (2020-07-10)Mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) have been shown to stimulate regeneration in the treatment of kidney injury. Renal regeneration is also thought to be stimulated by the activation of Sox9+ cells. However, whether and how the activation mechanisms... Adrenomedullin Induces Cardiac Lymphangiogenesis After Myocardial Infarction and Regulates Cardiac Edema Via Connexin 43.Claire E Trincot et al.Circulation research, 124(1), 101-113 (2018-12-26) Endothelial proteolytic activity and interaction with non-resorbing osteoclasts mediate bone elongation.Sara G Romeo et al.Nature cell biology, 21(4), 430-441 (2019-04-03) Snail1-expressing fibroblasts in the tumor microenvironment display mechanical properties that support metastasis.Jelena Stanisavljevic et al.Cancer research, 75(2), 284-295 (2014-12-10) A Common Embryonic Origin of Stem Cells Drives Developmental and Adult Neurogenesis.Daniel A Berg et al.Cell, 177(3), 654-668 (2019-04-02) Axin2+-Mesenchymal PDL Cells, Instead of K14+ Epithelial Cells, Play a Key Role in Rapid Cementum Growth.X Xie et al.Journal of dental research, 98(11), 1262-1270 (2019-08-28) Redox signalling to nuclear regulatory proteins by reactive oxygen species contributes to oestrogen-induced growth of breast cancer cells.V O Okoh et al.British journal of cancer, 112(10), 1687-1702 (2015-05-13) Toxicity and adverse effects of Tamoxifen and other anti-estrogen drugs.Geniey Yang et al.Pharmacology & therapeutics, 139(3), 392-404 (2013-05-29) Effect of some P-glycoprotein modulators on Rhodamine-123 absorption in guinea-pig ileum.Nicola Antonio Colabufo et al.Bioorganic & medicinal chemistry letters, 18(13), 3741-3744 (2008-06-06) Cyclodextrin Prevents Abdominal Aortic Aneurysm via Activation of Vascular Smooth Muscle Cell Transcription Factor EB.Haocheng Lu et al.Circulation, 142(5), 483-498 (2020-05-02) Sorafenib and nilotinib resensitize tamoxifen resistant breast cancer cells to tamoxifen treatment via estrogen receptor α.Astrid M Pedersen et al.International journal of oncology, 45(5), 2167-2175 (2014-09-02) Influence of FGF23 and Klotho on male reproduction: Systemic vs direct effects.Lasse Bøllehuus Hansen et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(9), 12436-12449 (2020-07-31) Potent estrogen receptor ligands based on bisphenols with a globular hydrophobic core.Yasuyuki Endo et al.Journal of medicinal chemistry, 48(12), 3941-3944 (2005-06-10) Upregulation of PKC-delta contributes to antiestrogen resistance in mammary tumor cells.Sanaa M Nabha et al.Oncogene, 24(19), 3166-3176 (2005-03-01) Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction.Qiaozhen Liu et al.Nature genetics, 51(4), 728-738 (2019-02-20) NKD1 marks intestinal and liver tumors linked to aberrant Wnt signaling.Jitka Stancikova et al.Cellular signalling, 27(2), 245-256 (2014-12-03) Nitrated fatty acids reverse pulmonary fibrosis by dedifferentiating myofibroblasts and promoting collagen uptake by alveolar macrophages.Aravind T Reddy et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(12), 5299-5310 (2014-09-26) c-Myb is required for plasma cell migration to bone marrow after immunization or infection.Kim L Good-Jacobson et al.The Journal of experimental medicine, 212(7), 1001-1009 (2015-06-17) The Homeodomain Transcription Factor NKX2.1 Is Essential for the Early Specification of Melanocortin Neuron Identity and Activates Pomc Expression in the Developing Hypothalamus.Daniela P Orquera et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(21), 4023-4035 (2019-03-20) Distinct outcomes in patients with different molecular subtypes of inflammatory breast cancer.Jingyu Zhou et al.Saudi medical journal, 35(11), 1324-1330 (2014-11-17) The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration.David Sala et al.Nature communications, 10(1), 1796-1796 (2019-04-19) Distinct outcomes in patients with different molecular subtypes of inflammatory breast cancer.Jingyu Zhou et al.Saudi medical journal, 35(11), 1324-1330 (2014-11-17) The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration.David Sala et al.Nature communications, 10(1), 1796-1796 (2019-04-19) Epiphyseal Cartilage Formation Involves Differential Dynamics of Various Cellular Populations During Embryogenesis.Yi Zhang et al.Frontiers in cell and developmental biology, 8, 122-122 (2020-03-27) Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis.Shaogui Wang et al.Autophagy, 15(11), 1954-1969 (2019-03-22) Cellular origins of cold-induced brown adipocytes in adult mice.Yun-Hee Lee et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(1), 286-299 (2014-11-14) Inducible Conditional Vascular-Specific Overexpression of Peroxisome Proliferator-Activated Receptor Beta/Delta Leads to Rapid Cardiac Hypertrophy.Kay-Dietrich Wagner et al.PPAR research, 2016, 7631085-7631085 (2016-04-09) Postnatal deficiency of ADAMTS1 ameliorates thoracic aortic aneurysm and dissection in mice.Shanshan Wang et al.Experimental physiology, 103(12), 1717-1731 (2018-09-08) AMP-activated protein kinase stimulates Warburg-like glycolysis and activation of satellite cells during muscle regeneration.Xing Fu et al.The Journal of biological chemistry, 290(44), 26445-26456 (2015-09-16) Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM.Yilin Tai et al.Neuron, 102(2), 358-372 (2019-03-09) Prepubertal skeletal muscle growth requires Pax7-expressing satellite cell-derived myonuclear contribution.John F Bachman et al.Development (Cambridge, England), 145(20) (2018-10-12) Conditional-ready mouse embryonic stem cell derived macrophages enable the study of essential genes in macrophage function.A T Y Yeung et al.Scientific reports, 5, 8908-8908 (2015-03-11) Notch receptor regulation of intestinal stem cell homeostasis and crypt regeneration.Alexis J Carulli et al.Developmental biology, 402(1), 98-108 (2015-04-04) TGF-beta receptor type-2 expression in cancer-associated fibroblasts regulates breast cancer cell growth and survival and is a prognostic marker in pre-menopausal breast cancer.S Busch et al.Oncogene, 34(1), 27-38 (2013-12-18) Selective deficiency in endothelial PTP1B protects from diabetes and endoplasmic reticulum stress-associated endothelial dysfunction via preventing endothelial cell apoptosis.Samuel Legeay et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 127, 110200-110200 (2020-05-18) A critical role for Neurofascin in regulating action potential initiation through maintenance of the axon initial segment.Barbara Zonta et al.Neuron, 69(5), 945-956 (2011-03-09) Ink4a/Arf-Dependent Loss of Parietal Cells Induced by Oxidative Stress Promotes CD44-Dependent Gastric Tumorigenesis.Ryo Seishima et al.Cancer prevention research (Philadelphia, Pa.), 8(6), 492-501 (2015-03-31) Estrogen receptor, Progesterone receptor, HER2 status and Ki67 index and responsiveness to adjuvant tamoxifen in postmenopausal high-risk breast cancer patients enrolled in the DBCG 77C trial.Ann S Knoop et al.European journal of cancer (Oxford, England : 1990), 50(8), 1412-1421 (2014-03-29) Astrocyte-Specific Deletion of Sox2 Promotes Functional Recovery After Traumatic Brain Injury.Chunhai Chen et al.Cerebral cortex (New York, N.Y. : 1991), 29(1), 54-69 (2017-11-22) Mesenchymal Precursor Cells in Adult Nerves Contribute to Mammalian Tissue Repair and Regeneration.Matthew J Carr et al.Cell stem cell, 24(2), 240-256 (2018-12-07) Design and synthesis of 1,3-biarylsulfanyl derivatives as new anti-breast cancer agents.Atul Kumar et al.Bioorganic & medicinal chemistry, 19(18), 5409-5419 (2011-08-30) Extracellular signal-regulated kinase 1/2 is involved in a tamoxifen neuroprotective effect in a lateral fluid percussion injury rat model.Yin-Tzu Tsai et al.The Journal of surgical research, 189(1), 106-116 (2014-03-19) Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs.Fan Fan et al.Toxicological sciences : an official journal of the Society of Toxicology, 145(2), 283-295 (2015-03-11) Tweety-homolog (Ttyh) Family Encodes the Pore-forming Subunits of the Swelling-dependent Volume-regulated Anion Channel (VRACswell) in the Brain.Young-Eun Han et al.Experimental neurobiology, 28(2), 183-215 (2019-05-30) Mature Vascular Smooth Muscle Cells, but Not Endothelial Cells, Serve as the Major Cellular Source of Intimal Hyperplasia in Vein Grafts.Weiwei Wu et al.Arteriosclerosis, thrombosis, and vascular biology, 40(8), 1870-1890 (2020-06-05) Antiseizure effects of TrkB kinase inhibition.Gumei Liu et al.Epilepsia, 55(8), 1264-1273 (2014-06-07) Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesis.Lindsay A Bonsignore et al.Oncotarget, 6(14), 12248-12263 (2015-04-25) Scap is required for sterol synthesis and crypt growth in intestinal mucosa.Matthew R McFarlane et al.Journal of lipid research, 56(8), 1560-1571 (2015-04-22) A Subset of Skin Macrophages Contributes to the Surveillance and Regeneration of Local Nerves.Julia Kolter et al.Immunity, 50(6), 1482-1497 (2019-06-16) Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo.Daniel Peña-Jimenez et al.The EMBO journal, 38(19), e101688-e101688 (2019-09-03) Blockade of CTLA-4 promotes the development of effector CD8+ T lymphocytes and the therapeutic effect of vaccination with an attenuated protozoan expressing NY-ESO-1.Luara Isabela Dos Santos et al.Cancer immunology, immunotherapy : CII, 64(3), 311-323 (2014-11-19) Blockade of CTLA-4 promotes the development of effector CD8+ T lymphocytes and the therapeutic effect of vaccination with an attenuated protozoan expressing NY-ESO-1.Luara Isabela Dos Santos et al.Cancer immunology, immunotherapy : CII, 64(3), 311-323 (2014-11-19) A subset of chondrogenic cells provides early mesenchymal progenitors in growing bones.Noriaki Ono et al.Nature cell biology, 16(12), 1157-1167 (2014-11-25) A Precision B Cell-Targeted Therapeutic Approach to Autoimmunity Caused by Phosphatidylinositol 3-Kinase Pathway Dysregulation.S Elizabeth Franks et al.Journal of immunology (Baltimore, Md. : 1950), 202(12), 3381-3393 (2019-05-12) Bmi1 Severs as a Potential Tumor-Initiating Cell Marker and Therapeutic Target in Esophageal Squamous Cell Carcinoma.Xiaochen Wang et al.Stem cells international, 2020, 8877577-8877577 (2020-09-05) Bmi1 expression in long-term germ stem cells.Yoshihiro Komai et al.Scientific reports, 4, 6175-6175 (2014-08-26) Transcription factor MafB in podocytes protects against the development of focal segmental glomerulosclerosis.Toshiaki Usui et al.Kidney international, 98(2), 391-403 (2020-07-06) Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis.Stanley C W Lee et al.Blood, 126(2), 167-175 (2015-06-04) Clinically used selective oestrogen receptor modulators increase LDL receptor activity in primary human lymphocytes.F Cerrato et al.British journal of pharmacology, 172(5), 1379-1394 (2014-11-15) Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation.Shaima'a Hamarsheh et al.Nature communications, 11(1), 1659-1659 (2020-04-05) Single-cell murine genetic fate mapping reveals bipotential hepatoblasts and novel multi-organ endoderm progenitors.Gabriel K El Sebae et al.Development (Cambridge, England), 145(19) (2018-09-21) The effects of endoxifen and other major metabolites of tamoxifen on the sulfation of estradiol catalyzed by human cytosolic sulfotransferases hSULT1E1 and hSULT1A1*1.Edwin J Squirewell et al.Drug metabolism and disposition: the biological fate of chemicals, 43(6), 843-850 (2015-03-31) c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly.Lilian Schimmel et al.Development (Cambridge, England), 147(7) (2020-02-29) Gene expression profiling identifies FYN as an important molecule in tamoxifen resistance and a predictor of early recurrence in patients treated with endocrine therapy.D Elias et al.Oncogene, 34(15), 1919-1927 (2014-06-03) The Wilms' tumour suppressor Wt1 is a major regulator of tumour angiogenesis and progression.Kay-Dietrich Wagner et al.Nature communications, 5, 5852-5852 (2014-12-17) Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation.Xueying Tian et al.The EMBO journal, 39(4), e102675-e102675 (2020-01-17) Lineage tracing reveals distinctive fates for mesothelial cells and submesothelial fibroblasts during peritoneal injury.Yi-Ting Chen et al.Journal of the American Society of Nephrology : JASN, 25(12), 2847-2858 (2014-05-24) Paneth cells promote angiogenesis and regulate portal hypertension in response to microbial signals.Mohsin Hassan et al.Journal of hepatology, 73(3), 628-639 (2020-03-25) A naringenin-tamoxifen combination impairs cell proliferation and survival of MCF-7 breast cancer cells.Talia Hatkevich et al.Experimental cell research, 327(2), 331-339 (2014-06-03) MiRNA-27a sensitizes breast cancer cells to treatment with Selective Estrogen Receptor Modulators.Bojan Ljepoja et al.Breast (Edinburgh, Scotland), 43, 31-38 (2018-11-12) Mesenchymal deficiency of Notch1 attenuates bleomycin-induced pulmonary fibrosis.Biao Hu et al.The American journal of pathology, 185(11), 3066-3075 (2015-09-12) The amyloid precursor protein controls adult hippocampal neurogenesis through GABAergic interneurons.Baiping Wang et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(40), 13314-13325 (2014-10-03) Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche that Maintains and Replenishes Splenic Red Pulp Macrophages.Alicia Bellomo et al.Immunity, 53(1), 127-142 (2020-06-21) Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like Behaviors.Alexis S Hill et al.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(10), 2368-2378 (2015-04-03) Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung.Daniel Lafkas et al.Nature, 528(7580), 127-131 (2015-11-19) Discovery of potent ligands for estrogen receptor beta by structure-based virtual screening.Jie Shen et al.Journal of medicinal chemistry, 53(14), 5361-5365 (2010-06-18) Ube3a reinstatement identifies distinct developmental windows in a murine Angelman syndrome model.Sara Silva-Santos et al.The Journal of clinical investigation, 125(5), 2069-2076 (2015-04-14) YAP1 is involved in replenishment of granule cell precursors following injury to the neonatal cerebellum.Zhaohui Yang et al.Developmental biology, 455(2), 458-472 (2019-08-04) Transgenic mouse technology in skin biology: inducible gene knockout in mice.Christian Günschmann et al.The Journal of investigative dermatology, 134(7), 1-4 (2014-06-14) Ectopic Atoh1 expression drives Merkel cell production in embryonic, postnatal and adult mouse epidermis.Stephen M Ostrowski et al.Development (Cambridge, England), 142(14), 2533-2544 (2015-07-04) The NuRD chromatin-remodeling complex enzyme CHD4 prevents hypoxia-induced endothelial Ripk3 transcription and murine embryonic vascular rupture.Sarah Colijn et al.Cell death and differentiation, 27(2), 618-631 (2019-06-27) Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.Rene Jackstadt et al.Cancer cell, 36(3), 319-336 (2019-09-19) Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes.Hugo Lee et al.Cell metabolism, 31(4), 822-836 (2020-03-30) Expression and Roles of the Immunoglobulin Superfamily Recognition Molecule Sidekick1 in Mouse Retina.Masahito Yamagata et al.Frontiers in molecular neuroscience, 11, 485-485 (2019-01-29) The effects of estradiol are modulated in a tissue-specific manner in mice with inducible inactivation of ERα after sexual maturation.Claes Ohlsson et al.American journal of physiology. Endocrinology and metabolism, 318(5), E646-E654 (2020-03-04) Meta-analysis of human cancer microarrays reveals GATA3 is integral to the estrogen receptor alpha pathway.Brian J Wilson et al.Molecular cancer, 7, 49-49 (2008-06-06) Conditional deletion of the glutamate transporter GLT-1 reveals that astrocytic GLT-1 protects against fatal epilepsy while neuronal GLT-1 contributes significantly to glutamate uptake into synaptosomes.Geraldine T Petr et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(13), 5187-5201 (2015-04-04) Growth of breast cancer cells by leptin is mediated via activation of the inflammasome: Critical roles of estrogen receptor signaling and reactive oxygen species production.Pawan Kumar Raut et al.Biochemical pharmacology, 161, 73-88 (2019-01-12) ASCL1 regulates proliferation of NG2-glia in the embryonic and adult spinal cord.Demetra P Kelenis et al.Glia, 66(9), 1862-1880 (2018-04-24) Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration.Stephen Gadomski et al.Cell reports, 31(4), 107572-107572 (2020-04-30) An Nfic-hedgehog signaling cascade regulates tooth root development.Yang Liu et al.Development (Cambridge, England), 142(19), 3374-3382 (2015-08-22) Striking parallels between carotid body glomus cell and adrenal chromaffin cell development.Dorit Hockman et al.Developmental biology, 444 Suppl 1, S308-S324 (2018-05-29) Non-canonical Wnt5a/Ror2 signaling regulates kidney morphogenesis by controlling intermediate mesoderm extension.Kangsun Yun et al.Human molecular genetics, 23(25), 6807-6814 (2014-08-02) Estetrol is a weak estrogen antagonizing estradiol-dependent mammary gland proliferation.C Gérard et al.The Journal of endocrinology, 224(1), 85-95 (2014-11-02) Combined inhibition of MAP kinase and KIT signaling synergistically destabilizes ETV1 and suppresses GIST tumor growth.Leili Ran et al.Cancer discovery, 5(3), 304-315 (2015-01-13) Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer.Aitziber Buqué et al.Nature communications, 11(1), 3819-3819 (2020-08-01) Identification of RBCK1 as a novel regulator of FKBPL: implications for tumor growth and response to tamoxifen.C Donley et al.Oncogene, 33(26), 3441-3450 (2013-08-06) VEGFR tyrosine kinase inhibitor II (VRI) induced vascular insufficiency in zebrafish as a model for studying vascular toxicity and vascular preservation.Shang Li et al.Toxicology and applied pharmacology, 280(3), 408-420 (2014-09-23) Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients.Linlin Lu et al.PloS one, 10(5), e0127524-e0127524 (2015-05-27) Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer.P Saladores et al.The pharmacogenomics journal, 15(1), 84-94 (2014-08-06) Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signalling pathways.Jhi Biau Foo et al.BMC complementary and alternative medicine, 14, 197-197 (2014-06-21) Antitumor-active cobalt-alkyne complexes derived from acetylsalicylic acid: studies on the mode of drug action.Ingo Ott et al.Journal of medicinal chemistry, 48(2), 622-629 (2005-01-22) TRPV2 is critical for the maintenance of cardiac structure and function in mice.Yuki Katanosaka et al.Nature communications, 5, 3932-3932 (2014-05-31) Kindlin-2 modulates MafA and β-catenin expression to regulate β-cell function and mass in mice.Ke Zhu et al.Nature communications, 11(1), 484-484 (2020-01-26) Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion.Jason R Plemel et al.Science advances, 6(3), eaay6324-eaay6324 (2020-01-31) Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF.Pradeep Ramalingam et al.Nature communications, 11(1), 666-666 (2020-02-06) Synthesis and preliminary biological evaluation of new carbon-11 labeled tetrahydroisoquinoline derivatives as SERM radioligands for PET imaging of ER expression in breast cancer.Mingzhang Gao et al.European journal of medicinal chemistry, 43(10), 2211-2219 (2008-02-15) Transformation of the intestinal epithelium by the MSI2 RNA-binding protein.Shan Wang et al.Nature communications, 6, 6517-6517 (2015-03-17) N-Benzyl-1-heteroaryl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamides as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1).Martin Allan et al.Bioorganic & medicinal chemistry letters, 19(4), 1218-1223 (2009-01-10) Adenosine deaminase acting on RNA 1 limits RIG-I RNA detection and suppresses IFN production responding to viral and endogenous RNAs.Yang S, Deng P, Zhu Z, et al. Journal of Immunology, 193(7), 3436-3445 (2014) Antiestrogenic constituents of the Thai medicinal plants Capparis flavicans and Vitex glabrata.Prathan Luecha et al.Journal of natural products, 72(11), 1954-1959 (2009-12-01) Risk-benefit profiles of women using tamoxifen for chemoprevention.Hazel B Nichols et al.Journal of the National Cancer Institute, 107(1), 354-354 (2014-12-06) Synergy of leptin/STAT3 with HER2 receptor induces tamoxifen resistance in breast cancer cells through regulation of apoptosis-related genes.Vassilis Papanikolaou et al.Cellular oncology (Dordrecht), 38(2), 155-164 (2014-12-30) Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.Monique E Verhaegen et al.The Journal of investigative dermatology, 135(5), 1415-1424 (2014-10-15) Regulation of the muscle fiber microenvironment by activated satellite cells during hypertrophy.Christopher S Fry et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(4), 1654-1665 (2014-01-01) The STAT5-GATA2 pathway is critical in basophil and mast cell differentiation and maintenance.Yapeng Li et al.Journal of immunology (Baltimore, Md. : 1950), 194(9), 4328-4338 (2015-03-25) Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.Nandita Sinha et al.European journal of medicinal chemistry, 46(2), 618-630 (2010-12-28) Selective estrogen receptor modulators with conformationally restricted side chains. Synthesis and structure-activity relationship of ERalpha-selective tetrahydroisoquinoline ligands.Johanne Renaud et al.Journal of medicinal chemistry, 48(2), 364-379 (2005-01-22) ERK1/2 can feedback-regulate cellular MEK1/2 levels.Seung-Keun Hong et al.Cellular signalling, 27(10), 1939-1948 (2015-07-15) Novel Murine Models of Cerebral Cavernous Malformations.Matthew R Detter et al.Angiogenesis, 23(4), 651-666 (2020-07-28) Embryonic Nkx2.1-expressing neural precursor cells contribute to the regional heterogeneity of adult V-SVZ neural stem cells.Ryan N Delgado et al.Developmental biology, 407(2), 265-274 (2015-09-22) CYP2D6 polymorphisms influence tamoxifen treatment outcomes in breast cancer patients: a meta-analysis.Zhiyu Zeng et al.Cancer chemotherapy and pharmacology, 72(2), 287-303 (2013-05-29) Synthesis and biological evaluation of phenolic 4,5-dihydroisoxazoles and 3-hydroxy ketones as estrogen receptor alpha and beta agonists.Pekka K Poutiainen et al.Bioorganic & medicinal chemistry, 18(10), 3437-3447 (2010-05-01) Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation.G A Weiner et al.Nature communications, 10(1), 2477-2477 (2019-06-07) Temporal-spatial changes in Sonic Hedgehog expression and signaling reveal different potentials of ventral mesencephalic progenitors to populate distinct ventral midbrain nuclei.Sandra Blaess et al.Neural development, 6, 29-29 (2011-06-22) HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders.Jerel Fields et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(5), 1921-1938 (2015-02-06) Developmental Phase Transitions in Spatial Organization of Spontaneous Activity in Postnatal Barrel Cortex Layer 4.Shingo Nakazawa et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(40), 7637-7650 (2020-09-06) Chronic activation of hexosamine biosynthesis in the heart triggers pathological cardiac remodeling.Diem Hong Tran et al.Nature communications, 11(1), 1771-1771 (2020-04-15) Microbial sensing by goblet cells controls immune surveillance of luminal antigens in the colon.K A Knoop et al.Mucosal immunology, 8(1), 198-210 (2014-07-10) A new combination therapy for premenopausal breast cancer.Farhat Yaqub The Lancet. Oncology, 15(8), e311-e311 (2014-08-15) Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation.Daniel J Puleston et al.Cell metabolism, 30(2), 352-363 (2019-05-28) The noncanonical BMP signaling pathway plays an important role in club cell regeneration.Md Shafiquzzaman et al.Stem cells (Dayton, Ohio), 38(3), 437-450 (2019-11-24) Exploring the origin and limitations of kidney regeneration.Tomomi Endo et al.The Journal of pathology, 236(2), 251-263 (2015-02-11) Influence of omega-3 fatty acids on Tamoxifen-induced suppression of rat mammary carcinogenesis.Andrea Manni et al.International journal of cancer, 134(7), 1549-1557 (2013-10-15) SH3BP4 Regulates Intestinal Stem Cells and Tumorigenesis by Modulating β-Catenin Nuclear Localization.Pedro Antas et al.Cell reports, 26(9), 2266-2273 (2019-02-28) MAFG-driven astrocytes promote CNS inflammation.Michael A Wheeler et al.Nature, 578(7796), 593-599 (2020-02-14) Unique role for dentate gyrus microglia in neuroblast survival and in VEGF-induced activation.Tirzah Kreisel et al.Glia, 67(4), 594-618 (2018-11-20) Defining the localization and molecular characteristic of minor salivary gland label-retaining cells.Hongjun Zhang et al.Stem cells (Dayton, Ohio), 32(8), 2267-2277 (2014-04-10) Ubiquitous expression of the Pik3caH1047R mutation promotes hypoglycemia, hypoinsulinemia, and organomegaly.Kathryn M Kinross et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(4), 1426-1434 (2015-01-01) Worse breast cancer prognosis of BRCA1/BRCA2 mutation carriers: what's the evidence? A systematic review with meta-analysis.Alexandra J van den Broek et al.PloS one, 10(3), e0120189-e0120189 (2015-03-31) Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.Denis Fourches et al.Chemical research in toxicology, 23(1), 171-183 (2009-12-18) Merlin status regulates p75(NTR) expression and apoptotic signaling in Schwann cells following nerve injury.Iram Ahmad et al.Neurobiology of disease, 82, 114-122 (2015-06-10) Downregulation of Sphingosine 1-Phosphate Receptor 1 Promotes the Switch from Tangential to Radial Migration in the OB.Julieta Alfonso et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(40), 13659-13672 (2015-10-09) The histone methyltransferase EZH2 primes the early differentiation of follicular helper T cells during acute viral infection.Xiangyu Chen et al.Cellular & molecular immunology, 17(3), 247-260 (2019-03-08) Multicolor analysis of oligodendrocyte morphology, interactions, and development with Brainbow.Laura Dumas et al.Glia, 63(4), 699-717 (2014-12-23) Cycling Stem Cells Are Radioresistant and Regenerate the Intestine.Xiaole Sheng et al.Cell reports, 32(4), 107952-107952 (2020-07-30) New cell culture model for aromatase inhibitor-resistant breast cancer shows sensitivity to fulvestrant treatment and cross-resistance between letrozole and exemestane.Stine Hole et al.International journal of oncology, 46(4), 1481-1490 (2015-01-28) Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice.Aparna Raval et al.PloS one, 10(7), e0131722-e0131722 (2015-07-03) Age-Related Changes in Synaptic Plasticity Associated with Mossy Fiber Terminal Integration during Adult Neurogenesis.Karl D Murray et al.eNeuro, 7(3) (2020-04-26) MLL1 is required for PAX7 expression and satellite cell self-renewal in mice.Gregory C Addicks et al.Nature communications, 10(1), 4256-4256 (2019-09-20) Rapid synthesis of 4-benzylidene and 4-[bis-(4-methoxyphenyl)-methylene-2-substituted phenyl-benzopyrans as potential selective estrogen receptor modulators (SERMs) using McMurry coupling reaction.Atul Gupta et al.Bioorganic & medicinal chemistry letters, 16(23), 6006-6012 (2006-09-19) Tamoxifen citrate: a glimmer of hope for silicosis.Omer Yoldas et al.The Journal of surgical research, 193(1), 429-434 (2014-09-15) YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury.Lara Planas-Paz et al.Cell stem cell, 25(1), 39-53 (2019-05-14) F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner.Kanae Yumimoto et al.The Journal of clinical investigation, 125(2), 621-635 (2015-01-03) Clonal analysis reveals laminar fate multipotency and daughter cell apoptosis of mouse cortical intermediate progenitors.Anca B Mihalas et al.Development (Cambridge, England), 145(17) (2018-09-16) Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance.Sarah A Dabydeen et al.Carcinogenesis, 36(1), 122-132 (2014-11-26) Optimization of tamoxifen-induced Cre activity and its effect on immune cell populations.Rachel S Donocoff et al.Scientific reports, 10(1), 15244-15244 (2020-09-19) Breast cancer chemoprevention: the saga of underuse continues.D Lawrence Wickerham et al.Journal of the National Cancer Institute, 107(1), 399-399 (2014-12-06) YAP1 is involved in replenishment of granule cell precursors following injury to the neonatal cerebellum.Zhaohui Yang et al.Developmental biology, 455(2), 458-472 (2019-08-04) Transgenic mouse technology in skin biology: inducible gene knockout in mice.Christian Günschmann et al.The Journal of investigative dermatology, 134(7), 1-4 (2014-06-14) Ectopic Atoh1 expression drives Merkel cell production in embryonic, postnatal and adult mouse epidermis.Stephen M Ostrowski et al.Development (Cambridge, England), 142(14), 2533-2544 (2015-07-04) A naringenin-tamoxifen combination impairs cell proliferation and survival of MCF-7 breast cancer cells.Talia Hatkevich et al.Experimental cell research, 327(2), 331-339 (2014-06-03) Cell type-specific genotoxicity in estrogen-exposed ovarian and fallopian epithelium.Liang Song et al.BMC cancer, 20(1), 1020-1020 (2020-10-23) Chronic oxidative stress causes estrogen-independent aggressive phenotype, and epigenetic inactivation of estrogen receptor alpha in MCF-7 breast cancer cells.Prathap Kumar S Mahalingaiah et al.Breast cancer research and treatment, 153(1), 41-56 (2015-07-26) The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells.Gautam K Malhotra et al.BMC developmental biology, 14, 47-47 (2014-12-21) Delayed inhibition of VEGF signaling after stroke attenuates blood-brain barrier breakdown and improves functional recovery in a comorbidity-dependent manner.Patrick Reeson et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(13), 5128-5143 (2015-04-04) PD-1 blockade attenuates immunosuppressive myeloid cells due to inhibition of CD47/SIRPα axis in HPV negative head and neck squamous cell carcinoma.Guang-Tao Yu et al.Oncotarget, 6(39), 42067-42080 (2015-11-18) CD45 ligation expands Tregs by promoting interactions with DCs.Geoffrey Camirand et al.The Journal of clinical investigation, 124(10), 4603-4613 (2014-09-10) The Rho GTPase Cdc42 regulates hair cell planar polarity and cellular patterning in the developing cochlea.Anna Kirjavainen et al.Biology open, 4(4), 516-526 (2015-03-15) Optical reconstruction of murine colorectal mucosa at cellular resolution.Cambrian Y Liu et al.American journal of physiology. Gastrointestinal and liver physiology, 308(9), G721-G735 (2015-02-28) Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium.Thierry Jardé et al.Cell stem cell, 27(4), 646-662 (2020-07-22) SDF-1/CXCR4 axis in Tie2-lineage cells including endothelial progenitor cells contributes to bone fracture healing.Yohei Kawakami et al.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 30(1), 95-105 (2014-08-19) Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression.Jesse W Williams et al.Nature immunology, 21(10), 1194-1204 (2020-09-09) Rapid and highly efficient inducible cardiac gene knockout in adult mice using AAV-mediated expression of Cre recombinase.Werfel S, Jungmann A, Lehmann L, et al. Cardiovascular Research, 104(1), 15-23 (2014) Progesterone receptor-B enhances estrogen responsiveness of breast cancer cells via scaffolding PELP1- and estrogen receptor-containing transcription complexes.A R Daniel et al.Oncogene, 34(4), 506-515 (2014-01-29) A Versatile Cell Death Screening Assay Using Dye-Stained Cells and Multivariate Image Analysis.Tony J Collins et al.Assay and drug development technologies, 13(9), 547-557 (2015-10-01) Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch.Erika López-Arribillaga et al.Development (Cambridge, England), 142(1), 41-50 (2014-12-07) Autism-Associated Insertion Mutation (InsG) of Shank3 Exon 21 Causes Impaired Synaptic Transmission and Behavioral Deficits.Haley E Speed et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(26), 9648-9665 (2015-07-03) Phosphorylation Alters Oestrogen Receptor β-Mediated Transcription in Neurones.E Pinceti et al.Journal of neuroendocrinology, 27(12), 861-871 (2015-10-07) Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.Yong-Hua Wang et al.Bioorganic & medicinal chemistry letters, 15(18), 4076-4084 (2005-07-02) Therapeutic efficacy of p53 restoration in Mdm2-overexpressing tumors.Qin Li et al.Molecular cancer research : MCR, 12(6), 901-911 (2014-03-07) Synthesis of new alkylaminooxysterols with potent cell differentiating activities: identification of leads for the treatment of cancer and neurodegenerative diseases.Philippe de Medina et al.Journal of medicinal chemistry, 52(23), 7765-7777 (2009-10-14) Interferon regulatory factor 9 is an essential mediator of heart dysfunction and cell death following myocardial ischemia/reperfusion injury.Zhang Y, Liu X, She ZG, et al. Basic Research in Cardiology, 109(5), 434-434 (2014) Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma.Clare C Davies et al.Cancer research, 74(12), 3344-3356 (2014-04-10) Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche that Maintains and Replenishes Splenic Red Pulp Macrophages.Alicia Bellomo et al.Immunity, 53(1), 127-142 (2020-06-21) The amyloid precursor protein controls adult hippocampal neurogenesis through GABAergic interneurons.Baiping Wang et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(40), 13314-13325 (2014-10-03) Discovery of potent ligands for estrogen receptor beta by structure-based virtual screening.Jie Shen et al.Journal of medicinal chemistry, 53(14), 5361-5365 (2010-06-18) Ube3a reinstatement identifies distinct developmental windows in a murine Angelman syndrome model.Sara Silva-Santos et al.The Journal of clinical investigation, 125(5), 2069-2076 (2015-04-14) MiRNA-27a sensitizes breast cancer cells to treatment with Selective Estrogen Receptor Modulators.Bojan Ljepoja et al.Breast (Edinburgh, Scotland), 43, 31-38 (2018-11-12) Mesenchymal deficiency of Notch1 attenuates bleomycin-induced pulmonary fibrosis.Biao Hu et al.The American journal of pathology, 185(11), 3066-3075 (2015-09-12) Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like Behaviors.Alexis S Hill et al.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(10), 2368-2378 (2015-04-03) Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung.Daniel Lafkas et al.Nature, 528(7580), 127-131 (2015-11-19) The NuRD chromatin-remodeling complex enzyme CHD4 prevents hypoxia-induced endothelial Ripk3 transcription and murine embryonic vascular rupture.Sarah Colijn et al.Cell death and differentiation, 27(2), 618-631 (2019-06-27) Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.Rene Jackstadt et al.Cancer cell, 36(3), 319-336 (2019-09-19) Striking parallels between carotid body glomus cell and adrenal chromaffin cell development.Dorit Hockman et al.Developmental biology, 444 Suppl 1, S308-S324 (2018-05-29) Non-canonical Wnt5a/Ror2 signaling regulates kidney morphogenesis by controlling intermediate mesoderm extension.Kangsun Yun et al.Human molecular genetics, 23(25), 6807-6814 (2014-08-02) Estetrol is a weak estrogen antagonizing estradiol-dependent mammary gland proliferation.C Gérard et al.The Journal of endocrinology, 224(1), 85-95 (2014-11-02) Expression of DNMT1 in neural stem/precursor cells is critical for survival of newly generated neurons in the adult hippocampus.Hirofumi Noguchi et al.Neuroscience research, 95, 1-11 (2015-02-11) Using a sequence of estrogen response elements as a DNA aptamer for estrogen receptors in vitro.Xu He et al.Nucleic acid therapeutics, 25(3), 152-161 (2015-03-04) Controversy of physiological vs. pharmacological effects of BMP signaling: Constitutive activation of BMP type IA receptor-dependent signaling in osteoblast lineage enhances bone formation and resorption, not affecting net bone mass.Nobuhiro Kamiya et al.Bone, 138, 115513-115513 (2020-07-01) Intestinal E-cadherin Deficiency Aggravates Dextran Sodium Sulfate-Induced Colitis.Jessica I Grill et al.Digestive diseases and sciences, 60(4), 895-902 (2015-01-31) A Novel Birthdate-Labeling Method Reveals Segregated Parallel Projections of Mitral and External Tufted Cells in the Main Olfactory System.Tatsumi Hirata et al.eNeuro, 6(6) (2019-11-02) Ultra-high performance liquid chromatography tandem mass spectrometric method for the determination of tamoxifen, N-desmethyltamoxifen, 4-hydroxytamoxifen and endoxifen in dried blood spots--development, validation and clinical application during breast cancer adjuvant therapy.Marina Venzon Antunes et al.Talanta, 132, 775-784 (2014-12-06) Association of aromatase inhibitors with coronary heart disease in women with early breast cancer.B Seruga et al.Cancer investigation, 32(4), 99-104 (2014-02-20) The Fgf8 subfamily (Fgf8, Fgf17 and Fgf18) is required for closure of the embryonic ventral body wall.Michael Boylan et al.Development (Cambridge, England), 147(21) (2020-09-11) Quiescent sox2(+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma.Robert J Vanner et al.Cancer cell, 26(1), 33-47 (2014-06-24) Reelin protects against amyloid β toxicity in vivo.Courtney Lane-Donovan et al.Science signaling, 8(384), ra67-ra67 (2015-07-15) SIRT1 suppresses self-renewal of adult hippocampal neural stem cells.Chen-Yan Ma et al.Development (Cambridge, England), 141(24), 4697-4709 (2014-12-04) Synthesis and biological evaluation of 2,3,4-triarylbenzopyran derivatives as SERM and therapeutic agent for breast cancer.Shailesh Kumar et al.Bioorganic & medicinal chemistry, 17(19), 6832-6840 (2009-09-11) Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymal transition in MCF7 breast cancer cells.Ylenia Lombardo et al.Breast cancer research : BCR, 16(3), R62-R62 (2014-06-13) Study of tamoxifen urinary metabolites in rat by ultra-high-performance liquid chromatography time-of-flight mass spectrometry.Juan C Domínguez-Romero et al.Biomedical chromatography : BMC, 29(8), 1220-1228 (2015-01-23) Survival outcome in endometrial cancer patients according to hereditary predisposition.Heon Jong Yoo et al.Taiwanese journal of obstetrics & gynecology, 54(1), 24-28 (2015-02-14) Combined inhibition of MAP kinase and KIT signaling synergistically destabilizes ETV1 and suppresses GIST tumor growth.Leili Ran et al.Cancer discovery, 5(3), 304-315 (2015-01-13) Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes.Hugo Lee et al.Cell metabolism, 31(4), 822-836 (2020-03-30) Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer.Aitziber Buqué et al.Nature communications, 11(1), 3819-3819 (2020-08-01) Identification of RBCK1 as a novel regulator of FKBPL: implications for tumor growth and response to tamoxifen.C Donley et al.Oncogene, 33(26), 3441-3450 (2013-08-06) VEGFR tyrosine kinase inhibitor II (VRI) induced vascular insufficiency in zebrafish as a model for studying vascular toxicity and vascular preservation.Shang Li et al.Toxicology and applied pharmacology, 280(3), 408-420 (2014-09-23) Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients.Linlin Lu et al.PloS one, 10(5), e0127524-e0127524 (2015-05-27) Aurora kinase B is important for antiestrogen resistant cell growth and a potential biomarker for tamoxifen resistant breast cancer.Sarah L Larsen et al.BMC cancer, 15, 239-239 (2015-04-18) Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages.Chao Li et al.eLife, 9 (2020-01-09) Antitumor-active cobalt-alkyne complexes derived from acetylsalicylic acid: studies on the mode of drug action.Ingo Ott et al.Journal of medicinal chemistry, 48(2), 622-629 (2005-01-22) TRPV2 is critical for the maintenance of cardiac structure and function in mice.Yuki Katanosaka et al.Nature communications, 5, 3932-3932 (2014-05-31) Kindlin-2 modulates MafA and β-catenin expression to regulate β-cell function and mass in mice.Ke Zhu et al.Nature communications, 11(1), 484-484 (2020-01-26) Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF.Pradeep Ramalingam et al.Nature communications, 11(1), 666-666 (2020-02-06) Shotgun ecotoxicoproteomics of Daphnia pulex: biochemical effects of the anticancer drug tamoxifen.Myriam Borgatta et al.Journal of proteome research, 14(1), 279-291 (2014-10-29) Generation of a tamoxifen inducible Tnnt2MerCreMer knock-in mouse model for cardiac studies.Jianyun Yan et al.Genesis (New York, N.Y. : 2000), 53(6), 377-386 (2015-05-27) Brain endothelial TAK1 and NEMO safeguard the neurovascular unit.Dirk A Ridder et al.The Journal of experimental medicine, 212(10), 1529-1549 (2015-09-09) PKCθ-JunB axis via upregulation of VEGFR3 expression mediates hypoxia-induced pathological retinal neovascularization.Raj Kumar et al.Cell death & disease, 11(5), 325-325 (2020-05-10) Biomimetic syntheses and antiproliferative activities of racemic, natural (-), and unnnatural (+) glyceollin I.Rahul S Khupse et al.Journal of medicinal chemistry, 54(10), 3506-3523 (2011-04-26) Critical Role of TFEB-Mediated Lysosomal Biogenesis in Alcohol-Induced Pancreatitis in Mice and Humans.Shaogui Wang et al.Cellular and molecular gastroenterology and hepatology, 10(1), 59-81 (2020-01-29) Pharyngeal Satellite Cells Undergo Myogenesis Under Basal Conditions and Are Required for Pharyngeal Muscle Maintenance.Matthew E Randolph et al.Stem cells (Dayton, Ohio), 33(12), 3581-3595 (2015-07-17) Selective estrogen modulators as an anticancer tool: mechanisms of efficiency and resistance.Surojeet Sengupta et al.Advances in experimental medicine and biology, 630, 206-219 (2008-07-22) Prolyl isomerase PIN1 negatively regulates SGK1 stability to mediate tamoxifen resistance in breast cancer cells.Ara Jo et al.Anticancer research, 35(2), 785-794 (2015-02-11) Perfecting breast-cancer treatment--incremental gains and musculoskeletal pains.Dawn L Hershman The New England journal of medicine, 372(5), 477-478 (2014-12-17) Mayamycin, a cytotoxic polyketide from a Streptomyces strain isolated from the marine sponge Halichondria panicea.Imke Schneemann et al.Journal of natural products, 73(7), 1309-1312 (2010-06-16) Beta-cell regeneration from vimentin+/MafB+ cells after STZ-induced extreme beta-cell ablation.Yu Cheng et al.Scientific reports, 5, 11703-11703 (2015-07-02) SOXC proteins amplify canonical WNT signaling to secure nonchondrocytic fates in skeletogenesis.Pallavi Bhattaram et al.The Journal of cell biology, 207(5), 657-671 (2014-12-03) Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.Anne E Powell et al.American journal of physiology. Gastrointestinal and liver physiology, 307(1), G16-G23 (2014-05-17) Selective oestrogen receptor (ER) modulators reduce microglia reactivity in vivo after peripheral inflammation: potential role of microglial ERs.Silvia Tapia-Gonzalez et al.The Journal of endocrinology, 198(1), 219-230 (2008-05-08) Interpreting the CYP2D6 results from the International Tamoxifen Pharmacogenetics Consortium.M A Province et al.Clinical pharmacology and therapeutics, 96(2), 144-146 (2014-07-25) Acquisition of a Unique Mesenchymal Precursor-like Blastema State Underlies Successful Adult Mammalian Digit Tip Regeneration.Mekayla A Storer et al.Developmental cell, 52(4), 509-524 (2020-01-07) Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice.Wei-Wen Lim et al.PloS one, 15(1), e0227505-e0227505 (2020-01-10) Oncogenic G Protein GNAQ Induces Uveal Melanoma and Intravasation in Mice.Jenny Li-Ying Huang et al.Cancer research, 75(16), 3384-3397 (2015-06-27) TMEM100 is a key factor for specification of lymphatic endothelial progenitors.Eun-Hye Moon et al.Angiogenesis, 23(3), 339-355 (2020-03-01) Tamoxifen benefits and CYP2D6 testing in women with hormone receptor-positive breast cancer.Marcelle Kaplan et al.Clinical journal of oncology nursing, 17(2), 174-179 (2013-03-30) Changes in serum hydroxyvitamin D levels of breast cancer patients during tamoxifen treatment or chemotherapy in premenopausal breast cancer patients.Hee Jeong Kim et al.European journal of cancer (Oxford, England : 1990), 50(8), 1403-1411 (2014-04-08) Encoding of contextual fear memory in hippocampal-amygdala circuit.Woong Bin Kim et al.Nature communications, 11(1), 1382-1382 (2020-03-15) Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient.Neil McCarthy et al.Cell stem cell, 26(3), 391-402 (2020-02-23) Three-dimensional Imaging Reveals New Compartments and Structural Adaptations in Odontoblasts.M Khatibi Shahidi et al.Journal of dental research, 94(7), 945-954 (2015-04-04) Rapid activity-directed screening of estrogens by parallel coupling of liquid chromatography with a functional gene reporter assay and mass spectrometry.Willem Jonker et al.Journal of chromatography. A, 1406, 165-174 (2015-06-28) Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma.Olga Shakhova et al.PLoS genetics, 11(1), e1004877-e1004877 (2015-01-30) Life-long in vivo cell-lineage tracing shows that no oogenesis originates from putative germline stem cells in adult mice.Hua Zhang et al.Proceedings of the National Academy of Sciences of the United States of America, 111(50), 17983-17988 (2014-12-03) Long noncoding RNA SAM promotes myoblast proliferation through stabilizing Sugt1 and facilitating kinetochore assembly.Yuying Li et al.Nature communications, 11(1), 2725-2725 (2020-06-03) Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses.Nicolas Fasnacht et al.The Journal of experimental medicine, 211(11), 2265-2279 (2014-10-15) Development and validation of an UPLC-MS/MS method for the quantification of tamoxifen and its main metabolites in human scalp hair.Jan C Drooger et al.Journal of pharmaceutical and biomedical analysis, 114, 416-425 (2015-06-30) Important and critical scientific aspects in pharmacogenomics analysis: lessons from controversial results of tamoxifen and CYP2D6 studies.Kazuma Kiyotani et al.Journal of human genetics, 58(6), 327-333 (2013-05-10) Addendum: Ospemifene (Osphena) for dyspareunia (Med Lett Drugs Ther 2013; 55:55). The Medical letter on drugs and therapeutics, 55(1427), 84-84 (2013-11-28) Schwann cells, but not Oligodendrocytes, Depend Strictly on Dynamin 2 Function.Daniel Gerber et al.eLife, 8 (2019-01-17) Developing analytical approaches to explore the connection between endocrine-active pharmaceuticals in water to effects in fish.Tammy L Jones-Lepp et al.Analytical and bioanalytical chemistry, 407(21), 6481-6492 (2015-06-17) HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders.Jerel Fields et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(5), 1921-1938 (2015-02-06) Developmental Phase Transitions in Spatial Organization of Spontaneous Activity in Postnatal Barrel Cortex Layer 4.Shingo Nakazawa et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(40), 7637-7650 (2020-09-06) Checkpoint kinase 1 is essential for fetal and adult hematopoiesis.Fabian Schuler et al.EMBO reports, 20(8), e47026-e47026 (2019-08-06) FGF9 and FGF10 activate distinct signaling pathways to direct lung epithelial specification and branching.Yongjun Yin et al.Science signaling, 13(621) (2020-03-05) ARL13B, a Joubert Syndrome-Associated Protein, Is Critical for Retinogenesis and Elaboration of Mouse Photoreceptor Outer Segments.Tanya L Dilan et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(8), 1347-1364 (2018-12-24) The Role of MicroRNAs as Predictors of Response to Tamoxifen Treatment in Breast Cancer Patients.Nina G Egeland et al.International journal of molecular sciences, 16(10), 24243-24275 (2015-10-17) An Nfic-hedgehog signaling cascade regulates tooth root development.Yang Liu et al.Development (Cambridge, England), 142(19), 3374-3382 (2015-08-22) Deletion of IFT80 Impairs Epiphyseal and Articular Cartilage Formation Due to Disruption of Chondrocyte Differentiation.Xue Yuan et al.PloS one, 10(6), e0130618-e0130618 (2015-06-23) [Breast cancer: radiotherapy and estrogen signaling].Céline Bourgier et al.Bulletin du cancer, 101(7-8), 714-717 (2014-08-06) Elevated protein synthesis in microglia causes autism-like synaptic and behavioral aberrations.Zhi-Xiang Xu et al.Nature communications, 11(1), 1797-1797 (2020-04-15) IFT80 Is Required for Fracture Healing Through Controlling the Regulation of TGF-β Signaling in Chondrocyte Differentiation and Function.Min Liu et al.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 35(3), 571-582 (2019-10-24) Control of Adipocyte Thermogenesis and Lipogenesis through β3-Adrenergic and Thyroid Hormone Signal Integration.Adilson Guilherme et al.Cell reports, 31(5), 107598-107598 (2020-05-07) Identification of aquaporin 4 inhibitors using in vitro and in silico methods.Vincent J Huber et al.Bioorganic & medicinal chemistry, 17(1), 411-417 (2008-01-10) Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization.Jing Zhang et al.Cell metabolism, 31(6), 1136-1153 (2020-06-04) Transit amplifying cells coordinate mouse incisor mesenchymal stem cell activation.Jemma Victoria Walker et al.Nature communications, 10(1), 3596-3596 (2019-08-11) Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening.Christian Laggner et al.Journal of medicinal chemistry, 48(15), 4754-4764 (2005-07-22) Adgrf5 contributes to patterning of the endothelial deep layer in retina.C Niaudet et al.Angiogenesis, 22(4), 491-505 (2019-07-01) Reply to P.G. Tsoutsou et al and O. Kaidar-Person et al.Benjamin D Smith et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(36), 4573-4573 (2013-11-06) Hypoxic drive caused type 3 neovascularization in a preclinical model of exudative age-related macular degeneration.Lijuan Zhang et al.Human molecular genetics, 28(20), 3475-3485 (2019-09-14) Smaller reduction in 3D breast density associated with subsequent cancer recurrence in patients with breast cancer receiving adjuvant tamoxifen therapy.Jin You Kim et al.AJR. American journal of roentgenology, 202(4), 912-921 (2014-03-26) Effect of tamoxifen on fatty degeneration and atrophy of rotator cuff muscles in chronic rotator cuff tear: An animal model study.Edward Cho et al.Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 33(12), 1846-1853 (2015-07-01) Smooth Muscle Cell Reprogramming in Aortic Aneurysms.Pei-Yu Chen et al.Cell stem cell, 26(4), 542-557 (2020-04-04) Selective inhibition of RET mediated cell proliferation in vitro by the kinase inhibitor SPP86.John P Alao et al.BMC cancer, 14, 853-853 (2014-11-21) Genetic Analysis of the Organization, Development, and Plasticity of Corneal Innervation in Mice.Nacim Bouheraoua et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(7), 1150-1168 (2018-12-28) The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans.John L Johnson et al.Immunity, 52(5), 842-855 (2020-05-01) Effect of prior chemotherapy regimens on the efficacy of endocrine therapy within a German cohort of the TEAM trial.Michaela Bossart et al.Journal of cancer research and clinical oncology, 140(1), 117-126 (2013-11-26) Negative feedback control of neuronal activity by microglia.Ana Badimon et al.Nature, 586(7829), 417-423 (2020-10-02) Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells.Zeng-Jie Yang et al.Cancer cell, 14(2), 135-145 (2008-08-12) Loss of NFIX Transcription Factor Biases Postnatal Neural Stem/Progenitor Cells Toward Oligodendrogenesis.Bo Zhou et al.Stem cells and development, 24(18), 2114-2126 (2015-06-18) Arterial endoglin does not protect against arteriovenous malformations.Esha Singh et al.Angiogenesis, 23(4), 559-566 (2020-06-09) Sim1 inhibits bone formation by enhancing the sympathetic tone in male mice.Xunde Wang et al.Endocrinology, 156(4), 1408-1415 (2015-01-22) mTOR limits the recruitment of CD11b+Gr1+Ly6Chigh myeloid-derived suppressor cells in protecting against murine immunological hepatic injury.Yan Zhang et al.Journal of leukocyte biology, 95(6), 961-970 (2014-02-27) Conditional ablation and conditional rescue models for Casq2 elucidate the role of development and of cell-type specific expression of Casq2 in the CPVT2 phenotype.Daniel J Flores et al.Human molecular genetics, 27(9), 1533-1544 (2018-02-17) Tamoxifen toxicity in cultured retinal pigment epithelial cells is mediated by concurrent regulated cell death mechanisms.Leo A Kim et al.Investigative ophthalmology & visual science, 55(8), 4747-4758 (2014-07-06) MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer.Peter C Hart et al.Nature communications, 6, 6053-6053 (2015-02-06) Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade.Stanislao Igor Travisano et al.eLife, 8 (2019-12-04) Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.Naomi L Kruhlak et al.Toxicology mechanisms and methods, 18(2-3), 217-227 (2008-01-01) Lymphatic regulator PROX1 determines Schlemm's canal integrity and identity.Dae-Young Park et al.The Journal of clinical investigation, 124(9), 3960-3974 (2014-07-26) Antitumor agents. 266. Design, synthesis, and biological evaluation of novel 2-(furan-2-yl)naphthalen-1-ol derivatives as potent and selective antibreast cancer agents.Yizhou Dong et al.Journal of medicinal chemistry, 52(11), 3586-3590 (2009-05-12) CYP2D6 genotype and tamoxifen: considerations for proper nonprospective studies.M P Goetz et al.Clinical pharmacology and therapeutics, 96(2), 141-144 (2014-07-25) Tamoxifen induces apoptosis through cancerous inhibitor of protein phosphatase 2A-dependent phospho-Akt inactivation in estrogen receptor-negative human breast cancer cells.Chun-Yu Liu et al.Breast cancer research : BCR, 16(5), 431-431 (2014-09-18) Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status.Amandine Everard et al.Nature communications, 5, 5648-5648 (2014-12-06) Identification of a FGF18-expressing alveolar myofibroblast that is developmentally cleared during alveologenesis.Andrew S Hagan et al.Development (Cambridge, England), 147(2) (2019-12-22) Tumor necrosis factor receptor-associated factor 3 is a positive regulator of pathological cardiac hypertrophy.Xi Jiang et al.Hypertension (Dallas, Tex. : 1979), 66(2), 356-367 (2015-06-03) Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells.Kazutaka Murata et al.Cell stem cell, 26(3), 377-390 (2020-02-23) YAP Activity Is Necessary and Sufficient for Basal Progenitor Abundance and Proliferation in the Developing Neocortex.Milos Kostic et al.Cell reports, 27(4), 1103-1118 (2019-04-25) A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo.Magdalena Stasiulewicz et al.Development (Cambridge, England), 142(13), 2291-2303 (2015-05-23) Inducible neuronal inactivation of Sim1 in adult mice causes hyperphagic obesity.Kristen P Tolson et al.Endocrinology, 155(7), 2436-2444 (2014-04-30) The Hippo-YAP pathway regulates the proliferation of alveolar epithelial progenitors after acute lung injury.Chen Hu et al.Cell biology international, 43(10), 1174-1183 (2019-01-12) SKP1 drives the prophase I to metaphase I transition during male meiosis.Yongjuan Guan et al.Science advances, 6(13), eaaz2129-eaaz2129 (2020-04-02) Multiple targeting by the antitumor drug tamoxifen: a structure-activity study.Philippe de Médina et al.Current medicinal chemistry. Anti-cancer agents, 4(6), 491-508 (2004-12-08) Induction of OTUD4 by viral infection promotes antiviral responses through deubiquitinating and stabilizing MAVS.Tianzi Liuyu et al.Cell research, 29(1), 67-79 (2018-11-10) Interstitial cells of Cajal mediate nitrergic inhibitory neurotransmission in the murine gastrointestinal tract.Barbara Lies et al.American journal of physiology. Gastrointestinal and liver physiology, 307(1), G98-106 (2014-05-17) Specific bone cells produce DLL4 to generate thymus-seeding progenitors from bone marrow.Vionnie W C Yu et al.The Journal of experimental medicine, 212(5), 759-774 (2015-04-29) Pilot Trial of Selecting Molecularly Guided Therapy for Patients with Non-V600 BRAF-Mutant Metastatic Melanoma: Experience of the SU2C/MRA Melanoma Dream Team.Patricia M LoRusso et al.Molecular cancer therapeutics, 14(8), 1962-1971 (2015-06-13) Sexually Dimorphic Behavioral Profile in a Transgenic Model Enabling Targeted Recombination in Active Neurons in Response to Ketamine and (2R,6R)-Hydroxynorketamine Administration.David P Herzog et al.International journal of molecular sciences, 21(6) (2020-04-05) The Bulk of Autotaxin Activity Is Dispensable for Adult Mouse Life.Aggeliki Katsifa et al.PloS one, 10(11), e0143083-e0143083 (2015-11-17) Timed conditional null of connexin26 in mice reveals temporary requirements of connexin26 in key cochlear developmental events before the onset of hearing.Qing Chang et al.Neurobiology of disease, 73, 418-427 (2014-09-25) Astrocytic Epoxyeicosatrienoic Acid Signaling in the Medial Prefrontal Cortex Modulates Depressive-like Behaviors.Wenchao Xiong et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(23), 4606-4623 (2019-03-25) The effects of estradiol are modulated in a tissue-specific manner in mice with inducible inactivation of ERα after sexual maturation.Claes Ohlsson et al.American journal of physiology. Endocrinology and metabolism, 318(5), E646-E654 (2020-03-04) Meta-analysis of human cancer microarrays reveals GATA3 is integral to the estrogen receptor alpha pathway.Brian J Wilson et al.Molecular cancer, 7, 49-49 (2008-06-06) Conditional deletion of the glutamate transporter GLT-1 reveals that astrocytic GLT-1 protects against fatal epilepsy while neuronal GLT-1 contributes significantly to glutamate uptake into synaptosomes.Geraldine T Petr et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(13), 5187-5201 (2015-04-04) Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration.Stephen Gadomski et al.Cell reports, 31(4), 107572-107572 (2020-04-30) Astrocyte-derived BDNF supports myelin protein synthesis after cuprizone-induced demyelination.Clifton G Fulmer et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(24), 8186-8196 (2014-06-13) Synthesis, biological evaluation, structural-activity relationship, and docking study for a series of benzoxepin-derived estrogen receptor modulators.Irene Barrett et al.Bioorganic & medicinal chemistry, 16(21), 9554-9573 (2008-10-07) Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion.Jason R Plemel et al.Science advances, 6(3), eaay6324-eaay6324 (2020-01-31) PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis.Slim Mzoughi et al.Nature communications, 11(1), 3520-3520 (2020-07-16) KCa3.1 modulates neuroblast migration along the rostral migratory stream (RMS) in vivo.Kathryn L Turner et al.Cerebral cortex (New York, N.Y. : 1991), 24(9), 2388-2400 (2013-04-16) Intestinal Neurod1 expression impairs paneth cell differentiation and promotes enteroendocrine lineage specification.Hui Joyce Li et al.Scientific reports, 9(1), 19489-19489 (2019-12-22) Single-Cell RNA Profiling Reveals Adipocyte to Macrophage Signaling Sufficient to Enhance Thermogenesis.Felipe Henriques et al.Cell reports, 32(5), 107998-107998 (2020-08-07) Dynamin and endocytosis are required for the fusion of osteoclasts and myoblasts.Nah-Young Shin et al.The Journal of cell biology, 207(1), 73-89 (2014-10-08) Genetic Deletion of β-Arrestin-2 and the Mitigation of Established Airway Hyperresponsiveness in a Murine Asthma Model.Minyong Chen et al.American journal of respiratory cell and molecular biology, 53(3), 346-354 (2015-01-09) Zfx facilitates tumorigenesis caused by activation of the Hedgehog pathway.Colin J Palmer et al.Cancer research, 74(20), 5914-5924 (2014-08-29) Sustained Akt signaling in articular chondrocytes causes osteoarthritis via oxidative stress-induced senescence in mice.Jing Xie et al.Bone research, 7, 23-23 (2019-10-28) Understanding CYP2D6 and its role in tamoxifen metabolism.Edith Caroline Smith Oncology nursing forum, 40(6), 547-548 (2013-10-29) Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations during Wound Healing.Simon Joost et al.Cell reports, 25(3), 585-597 (2018-10-18) Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer.Priscilla Cheung et al.Cell stem cell, 27(4), 590-604 (2020-07-31) The in vivo genetic program of murine primordial lung epithelial progenitors.Laertis Ikonomou et al.Nature communications, 11(1), 635-635 (2020-02-02) Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria.Rahul Vijay et al.Nature immunology, 21(7), 790-801 (2020-05-20) Ins1-Cre and Ins1-CreER Gene Replacement Alleles Are Susceptible To Silencing By DNA Hypermethylation.Elham Mosleh et al.Endocrinology, 161(8) (2020-04-09) Aggravated brain injury after neonatal hypoxic ischemia in microglia-depleted mice.Shunichiro Tsuji et al.Journal of neuroinflammation, 17(1), 111-111 (2020-04-12) Changes in serum hydroxyvitamin D levels of breast cancer patients during tamoxifen treatment or chemotherapy in premenopausal breast cancer patients.Hee Jeong Kim et al.European journal of cancer (Oxford, England : 1990), 50(8), 1403-1411 (2014-04-08) Tamoxifen induces the development of hernia in mice by activating MMP-2 and MMP-13 expression.Xingzhe Ma et al.Biochimica et biophysica acta, 1852(5), 1038-1048 (2015-02-24) NF-κB signaling is required for XBP1 (unspliced and spliced)-mediated effects on antiestrogen responsiveness and cell fate decisions in breast cancer.Rong Hu et al.Molecular and cellular biology, 35(2), 379-390 (2014-11-05) Cardiomyocyte-Specific Deletion of Orai1 Reveals Its Protective Role in Angiotensin-II-Induced Pathological Cardiac Remodeling.Sebastian Segin et al.Cells, 9(5) (2020-05-02) Desmocollin-2 promotes intestinal mucosal repair by controlling integrin-dependent cell adhesion and migration.Sven Flemming et al.Molecular biology of the cell, 31(6), 407-418 (2020-01-23) Licensing of primordial germ cells for gametogenesis depends on genital ridge signaling.Yueh-Chiang Hu et al.PLoS genetics, 11(3), e1005019-e1005019 (2015-03-05) A glycolytic shift in Schwann cells supports injured axons.Elisabetta Babetto et al.Nature neuroscience, 23(10), 1215-1228 (2020-08-19) More treatment options for women with hormone receptor-positive breast cancer: guideline update, studies lead to advances in care.Carrie Printz Cancer, 120(19), 2939-2940 (2014-09-23) Pharmacological relevance of endoxifen in a laboratory simulation of breast cancer in postmenopausal patients.Philipp Y Maximov et al.Journal of the National Cancer Institute, 106(10), doi:10-doi:10 (2014-09-27) Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.Gustav Ahlin et al.Journal of medicinal chemistry, 51(19), 5932-5942 (2008-09-16) A misguided 'pill in the pocket' approach with flecainide leading to cardiac arrest.Daniel Kiblboeck et al.BMJ case reports, 2012, doi:10-doi:10 (2012-08-29) GATA4 represses an ileal program of gene expression in the proximal small intestine by inhibiting the acetylation of histone H3, lysine 27.B E Aronson et al.Biochimica et biophysica acta, 1839(11), 1273-1282 (2014-06-01) PV1 in Caveolae Controls Lung Endothelial Permeability.Joshua H Jones et al.American journal of respiratory cell and molecular biology, 63(4), 531-539 (2020-07-15) Synthesis and in vitro anti-tumor activity of new oxadiazole thioglycosides.M A Abu-Zaied et al.European journal of medicinal chemistry, 46(1), 229-235 (2010-12-01) FDA approval of paroxetine for menopausal hot flushes.Ronald J Orleans et al.The New England journal of medicine, 370(19), 1777-1779 (2014-05-09) A negative feedback loop controls NMDA receptor function in cortical interneurons via neuregulin 2/ErbB4 signalling.Detlef Vullhorst et al.Nature communications, 6, 7222-7222 (2015-06-02) Bax and Bak jointly control survival and dampen the early unfolded protein response in pancreatic β-cells under glucolipotoxic stress.Sarah A White et al.Scientific reports, 10(1), 10986-10986 (2020-07-06) Sonic hedgehog signaling is negatively regulated in reactive astrocytes after forebrain stab injury.R Vivian Allahyari et al.Scientific reports, 9(1), 565-565 (2019-01-27) Evaluation of a published in silico model and construction of a novel Bayesian model for predicting phospholipidosis inducing potential.Dennis J Pelletier et al.Journal of chemical information and modeling, 47(3), 1196-1205 (2007-04-13) Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.Kuei-Pin Chung et al.Nature communications, 10(1), 3390-3390 (2019-07-31) The Transcription Factor T-Bet Is Required for Optimal Type I Follicular Helper T Cell Maintenance During Acute Viral Infection.Pengcheng Wang et al.Frontiers in immunology, 10, 606-606 (2019-04-16) Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia.Xuehui Yang et al.Developmental biology, 321(1), 64-76 (2008-06-28) Endothelial Cell Lineage Analysis Does Not Provide Evidence for EMT in Adult Valve Homeostasis and Disease.Andrew J Kim et al.Anatomical record (Hoboken, N.J. : 2007), 302(1), 125-135 (2018-10-12) Minimally invasive treatment of Peyronie's disease: evidence-based progress.Gerald H Jordan et al.BJU international, 114(1), 16-24 (2014-01-23) Antifungal activity of tamoxifen: in vitro and in vivo activities and mechanistic characterization.Kristy Dolan et al.Antimicrobial agents and chemotherapy, 53(8), 3337-3346 (2009-06-03) A Phox2b BAC Transgenic Rat Line Useful for Understanding Respiratory Rhythm Generator Neural Circuitry.Keiko Ikeda et al.PloS one, 10(7), e0132475-e0132475 (2015-07-07) PTEN upregulation may explain the development of insulin resistance and type 2 diabetes with high dose statins.Yochai Birnbaum et al.Cardiovascular drugs and therapy, 28(5), 447-457 (2014-08-12) A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.David Buttar et al.Bioorganic & medicinal chemistry, 18(21), 7486-7496 (2010-09-28) Protein arginine methyltransferase 5 promotes cholesterol biosynthesis-mediated Th17 responses and autoimmunity.Lindsay M Webb et al.The Journal of clinical investigation, 130(4), 1683-1698 (2020-02-25) Synthesis and biological evaluation of 3,4,6-triaryl-2-pyranones as a potential new class of anti-breast cancer agents.Ravi Shankar et al.Bioorganic & medicinal chemistry, 17(11), 3847-3856 (2009-05-09) Occurrence and fate of selected anticancer, antimicrobial, and psychotropic pharmaceuticals in an urban river in a subcatchment of the Yodo River basin, Japan.Takashi Azuma et al.Environmental science and pollution research international, 22(23), 18676-18686 (2015-07-17) Extending an in vitro panel for estrogenicity testing: the added value of bioassays for measuring antiandrogenic activities and effects on steroidogenesis.Si Wang et al.Toxicological sciences : an official journal of the Society of Toxicology, 141(1), 78-89 (2014-06-15) Mitochondria: the gateway for tamoxifen-induced liver injury.Mariana P C Ribeiro et al.Toxicology, 323, 10-18 (2014-06-03) Casz1 is required for cardiomyocyte G1-to-S phase progression during mammalian cardiac development.Kerry M Dorr et al.Development (Cambridge, England), 142(11), 2037-2047 (2015-05-09) Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness.Sarah A Scott et al.Nature chemical biology, 5(2), 108-117 (2009-01-13) Pak2 Links TCR Signaling Strength to the Development of Regulatory T Cells and Maintains Peripheral Tolerance.Kyle Leonard O'Hagan et al.Journal of immunology (Baltimore, Md. : 1950), 195(4), 1564-1577 (2015-07-15) Unipotent, Atoh1+ progenitors maintain the Merkel cell population in embryonic and adult mice.Margaret C Wright et al.The Journal of cell biology, 208(3), 367-379 (2015-01-28) Essential role of mouse Dead end1 in the maintenance of spermatogonia.Yuki Niimi et al.Developmental biology, 445(1), 103-112 (2018-11-16) Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches.Svetoslav Chakarov et al.Science (New York, N.Y.), 363(6432) (2019-03-16) Effects of tamoxifen on the sex determination gene and the activation of sex reversal in the developing gonad of mice.Mingxi Yu et al.Toxicology, 321, 89-95 (2014-04-29) Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity.Phi T Nguyen et al.Cell, 182(2), 388-403 (2020-07-03) Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation.G A Weiner et al.Nature communications, 10(1), 2477-2477 (2019-06-07) Expression and Functional Analyses of Dlk1 in Muscle Stem Cells and Mesenchymal Progenitors during Muscle Regeneration.Lidan Zhang et al.International journal of molecular sciences, 20(13) (2019-07-07) The noncanonical BMP signaling pathway plays an important role in club cell regeneration.Md Shafiquzzaman et al.Stem cells (Dayton, Ohio), 38(3), 437-450 (2019-11-24) Defining the localization and molecular characteristic of minor salivary gland label-retaining cells.Hongjun Zhang et al.Stem cells (Dayton, Ohio), 32(8), 2267-2277 (2014-04-10) Ubiquitous expression of the Pik3caH1047R mutation promotes hypoglycemia, hypoinsulinemia, and organomegaly.Kathryn M Kinross et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(4), 1426-1434 (2015-01-01) Worse breast cancer prognosis of BRCA1/BRCA2 mutation carriers: what's the evidence? A systematic review with meta-analysis.Alexandra J van den Broek et al.PloS one, 10(3), e0120189-e0120189 (2015-03-31) Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.Denis Fourches et al.Chemical research in toxicology, 23(1), 171-183 (2009-12-18) Merlin status regulates p75(NTR) expression and apoptotic signaling in Schwann cells following nerve injury.Iram Ahmad et al.Neurobiology of disease, 82, 114-122 (2015-06-10) Downregulation of Sphingosine 1-Phosphate Receptor 1 Promotes the Switch from Tangential to Radial Migration in the OB.Julieta Alfonso et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(40), 13659-13672 (2015-10-09) Effect of prior chemotherapy regimens on the efficacy of endocrine therapy within a German cohort of the TEAM trial.Michaela Bossart et al.Journal of cancer research and clinical oncology, 140(1), 117-126 (2013-11-26) CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia.Ramprasad Ramakrishnan et al.Cell reports, 31(8), 107684-107684 (2020-05-28) Loss of aryl hydrocarbon receptor potentiates FoxM1 signaling to enhance self-renewal of colonic stem and progenitor cells.Huajun Han et al.The EMBO journal, 39(19), e104319-e104319 (2020-09-12) Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss.Fabrizio Thorel et al.Nature, 464(7292), 1149-1154 (2010-04-07) Neo-tanshinlactone inspired synthesis, in vitro evaluation of novel substituted benzocoumarin derivatives as potent anti-breast cancer agents.Koneni V Sashidhara et al.Bioorganic & medicinal chemistry letters, 20(23), 7127-7131 (2010-10-19) Synergy of leptin/STAT3 with HER2 receptor induces tamoxifen resistance in breast cancer cells through regulation of apoptosis-related genes.Vassilis Papanikolaou et al.Cellular oncology (Dordrecht), 38(2), 155-164 (2014-12-30) The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans.John L Johnson et al.Immunity, 52(5), 842-855 (2020-05-01) Evaluation of a published in silico model and construction of a novel Bayesian model for predicting phospholipidosis inducing potential.Dennis J Pelletier et al.Journal of chemical information and modeling, 47(3), 1196-1205 (2007-04-13) Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.Kuei-Pin Chung et al.Nature communications, 10(1), 3390-3390 (2019-07-31) The Transcription Factor T-Bet Is Required for Optimal Type I Follicular Helper T Cell Maintenance During Acute Viral Infection.Pengcheng Wang et al.Frontiers in immunology, 10, 606-606 (2019-04-16) Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia.Xuehui Yang et al.Developmental biology, 321(1), 64-76 (2008-06-28) Loss of NFIX Transcription Factor Biases Postnatal Neural Stem/Progenitor Cells Toward Oligodendrogenesis.Bo Zhou et al.Stem cells and development, 24(18), 2114-2126 (2015-06-18) The histone methyltransferase EZH2 primes the early differentiation of follicular helper T cells during acute viral infection.Xiangyu Chen et al.Cellular & molecular immunology, 17(3), 247-260 (2019-03-08) Multicolor analysis of oligodendrocyte morphology, interactions, and development with Brainbow.Laura Dumas et al.Glia, 63(4), 699-717 (2014-12-23) Cycling Stem Cells Are Radioresistant and Regenerate the Intestine.Xiaole Sheng et al.Cell reports, 32(4), 107952-107952 (2020-07-30) New cell culture model for aromatase inhibitor-resistant breast cancer shows sensitivity to fulvestrant treatment and cross-resistance between letrozole and exemestane.Stine Hole et al.International journal of oncology, 46(4), 1481-1490 (2015-01-28) Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice.Aparna Raval et al.PloS one, 10(7), e0131722-e0131722 (2015-07-03) Genetic Deletion of β-Arrestin-2 and the Mitigation of Established Airway Hyperresponsiveness in a Murine Asthma Model.Minyong Chen et al.American journal of respiratory cell and molecular biology, 53(3), 346-354 (2015-01-09) Novel Murine Models of Cerebral Cavernous Malformations.Matthew R Detter et al.Angiogenesis, 23(4), 651-666 (2020-07-28) Zfx facilitates tumorigenesis caused by activation of the Hedgehog pathway.Colin J Palmer et al.Cancer research, 74(20), 5914-5924 (2014-08-29) RAD1901: a novel, orally bioavailable selective estrogen receptor degrader that demonstrates antitumor activity in breast cancer xenograft models.Fiona Garner et al.Anti-cancer drugs, 26(9), 948-956 (2015-07-15) Age-Related Changes in Synaptic Plasticity Associated with Mossy Fiber Terminal Integration during Adult Neurogenesis.Karl D Murray et al.eNeuro, 7(3) (2020-04-26) MLL1 is required for PAX7 expression and satellite cell self-renewal in mice.Gregory C Addicks et al.Nature communications, 10(1), 4256-4256 (2019-09-20) Rapid synthesis of 4-benzylidene and 4-[bis-(4-methoxyphenyl)-methylene-2-substituted phenyl-benzopyrans as potential selective estrogen receptor modulators (SERMs) using McMurry coupling reaction.Atul Gupta et al.Bioorganic & medicinal chemistry letters, 16(23), 6006-6012 (2006-09-19) Tamoxifen citrate: a glimmer of hope for silicosis.Omer Yoldas et al.The Journal of surgical research, 193(1), 429-434 (2014-09-15) YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury.Lara Planas-Paz et al.Cell stem cell, 25(1), 39-53 (2019-05-14) Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer.Priscilla Cheung et al.Cell stem cell, 27(4), 590-604 (2020-07-31) The in vivo genetic program of murine primordial lung epithelial progenitors.Laertis Ikonomou et al.Nature communications, 11(1), 635-635 (2020-02-02) HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.Taranjit Singh Rai et al.Genes & development, 28(24), 2712-2725 (2014-12-17) Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria.Rahul Vijay et al.Nature immunology, 21(7), 790-801 (2020-05-20) Ins1-Cre and Ins1-CreER Gene Replacement Alleles Are Susceptible To Silencing By DNA Hypermethylation.Elham Mosleh et al.Endocrinology, 161(8) (2020-04-09) Aggravated brain injury after neonatal hypoxic ischemia in microglia-depleted mice.Shunichiro Tsuji et al.Journal of neuroinflammation, 17(1), 111-111 (2020-04-12) Microbial Disruption of Autophagy Alters Expression of the RISC Component AGO2, a Critical Regulator of the miRNA Silencing Pathway.Michal Sibony et al.Inflammatory bowel diseases, 21(12), 2778-2786 (2015-09-04) Synthesis and biological evaluation of 3,4,6-triaryl-2-pyranones as a potential new class of anti-breast cancer agents.Ravi Shankar et al.Bioorganic & medicinal chemistry, 17(11), 3847-3856 (2009-05-09) Occurrence and fate of selected anticancer, antimicrobial, and psychotropic pharmaceuticals in an urban river in a subcatchment of the Yodo River basin, Japan.Takashi Azuma et al.Environmental science and pollution research international, 22(23), 18676-18686 (2015-07-17) CYP2D6 genotype and adjuvant tamoxifen.D A Berry Clinical pharmacology and therapeutics, 96(2), 138-140 (2014-07-25) GATA4 represses an ileal program of gene expression in the proximal small intestine by inhibiting the acetylation of histone H3, lysine 27.B E Aronson et al.Biochimica et biophysica acta, 1839(11), 1273-1282 (2014-06-01) In vivo ectopic Ngn1 and Neurod1 convert neonatal cochlear glial cells into spiral ganglion neurons.Xiang Li et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(3), 4764-4782 (2020-02-07) Ca2+ signalling behaviours of intramuscular interstitial cells of Cajal in the murine colon.Bernard T Drumm et al.The Journal of physiology, 597(14), 3587-3617 (2019-05-28) Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.Lihong Zhan et al.PLoS biology, 17(2), e3000134-e3000134 (2019-02-09) E-cadherin is required for metastasis in multiple models of breast cancer.Veena Padmanaban et al.Nature, 573(7774), 439-444 (2019-09-06) Selective depletion of vascular EC-SOD augments chronic hypoxic pulmonary hypertension.Eva Nozik-Grayck et al.American journal of physiology. Lung cellular and molecular physiology, 307(11), L868-L876 (2014-10-19) USP22 promotes IRF3 nuclear translocation and antiviral responses by deubiquitinating the importin protein KPNA2.Zeng Cai et al.The Journal of experimental medicine, 217(5) (2020-03-05) Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen.Antoni Hurtado et al.Nature, 456(7222), 663-666 (2008-11-14) Topical KGF treatment as a therapeutic strategy for vaginal atrophy in a model of ovariectomized mice.Simona Ceccarelli et al.Journal of cellular and molecular medicine, 18(9), 1895-1907 (2014-08-05) Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.Barton Wicksteed et al.Diabetes, 59(12), 3090-3098 (2010-08-31) Ependymal Vps35 Promotes Ependymal Cell Differentiation and Survival, Suppresses Microglial Activation, and Prevents Neonatal Hydrocephalus.Kong-Yan Wu et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(19), 3862-3879 (2020-04-16) Inducible knockout of Mef2a, -c, and -d from nestin-expressing stem/progenitor cells and their progeny unexpectedly uncouples neurogenesis and dendritogenesis in vivo.Sarah E Latchney et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(12), 5059-5071 (2015-08-20) Unipotent, Atoh1+ progenitors maintain the Merkel cell population in embryonic and adult mice.Margaret C Wright et al.The Journal of cell biology, 208(3), 367-379 (2015-01-28) Essential role of mouse Dead end1 in the maintenance of spermatogonia.Yuki Niimi et al.Developmental biology, 445(1), 103-112 (2018-11-16) Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches.Svetoslav Chakarov et al.Science (New York, N.Y.), 363(6432) (2019-03-16) Effects of tamoxifen on the sex determination gene and the activation of sex reversal in the developing gonad of mice.Mingxi Yu et al.Toxicology, 321, 89-95 (2014-04-29) IDH2 and NPM1 Mutations Cooperate to Activate Hoxa9/Meis1 and Hypoxia Pathways in Acute Myeloid Leukemia.Yoko Ogawara et al.Cancer research, 75(10), 2005-2016 (2015-03-22) Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium.David Castillo et al.Development (Cambridge, England), 141(15), 2993-3002 (2014-07-06) A Phox2b BAC Transgenic Rat Line Useful for Understanding Respiratory Rhythm Generator Neural Circuitry.Keiko Ikeda et al.PloS one, 10(7), e0132475-e0132475 (2015-07-07) PTEN upregulation may explain the development of insulin resistance and type 2 diabetes with high dose statins.Yochai Birnbaum et al.Cardiovascular drugs and therapy, 28(5), 447-457 (2014-08-12) Pak2 Links TCR Signaling Strength to the Development of Regulatory T Cells and Maintains Peripheral Tolerance.Kyle Leonard O'Hagan et al.Journal of immunology (Baltimore, Md. : 1950), 195(4), 1564-1577 (2015-07-15) Reply to P.G. Tsoutsou et al and O. Kaidar-Person et al.Benjamin D Smith et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(36), 4573-4573 (2013-11-06) A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.David Buttar et al.Bioorganic & medicinal chemistry, 18(21), 7486-7496 (2010-09-28) Protein arginine methyltransferase 5 promotes cholesterol biosynthesis-mediated Th17 responses and autoimmunity.Lindsay M Webb et al.The Journal of clinical investigation, 130(4), 1683-1698 (2020-02-25) Estradiol and tamoxifen enhance invasion of endometrial stromal cells in a three-dimensional coculture model of adenomyosis.Anthony Henry Taylor et al.Fertility and sterility, 101(1), 288-293 (2013-11-06) Cortical Observation by Synchronous Multifocal Optical Sampling Reveals Widespread Population Encoding of Actions.Isaac V Kauvar et al.Neuron, 107(2), 351-367 (2020-05-21) Epigenetic priming by Dot1l in lymphatic endothelial progenitors ensures normal lymphatic development and function.Hyunjin Yoo et al.Cell death & disease, 11(1), 14-14 (2020-01-08) Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia.Stephen S Chung et al.Science translational medicine, 6(238), 238ra71-238ra71 (2014-05-30) Identifying off-target effects and hidden phenotypes of drugs in human cells.Marnie L MacDonald et al.Nature chemical biology, 2(6), 329-337 (2006-05-09) A misguided 'pill in the pocket' approach with flecainide leading to cardiac arrest.Daniel Kiblboeck et al.BMJ case reports, 2012, doi:10-doi:10 (2012-08-29) PV1 in Caveolae Controls Lung Endothelial Permeability.Joshua H Jones et al.American journal of respiratory cell and molecular biology, 63(4), 531-539 (2020-07-15) Deletion of Stat3 in hematopoietic cells enhances thrombocytosis and shortens survival in a JAK2-V617F mouse model of MPN.Jean Grisouard et al.Blood, 125(13), 2131-2140 (2015-01-18) Distinct Airway Epithelial Stem Cells Hide among Club Cells but Mobilize to Promote Alveolar Regeneration.Jaymin J Kathiriya et al.Cell stem cell, 26(3), 346-358 (2020-01-25) PharmGKB summary: tamoxifen pathway, pharmacokinetics.Daniel J Klein et al.Pharmacogenetics and genomics, 23(11), 643-647 (2013-08-22) FMR1 Reactivating Treatments in Fragile X iPSC-Derived Neural Progenitors In Vitro and In Vivo.Dan Vershkov et al.Cell reports, 26(10), 2531-2539 (2019-03-07) St. Gallen endocrine response classes predict recurrence rates over time.R H T Koornstra et al.Breast (Edinburgh, Scotland), 24(6), 705-712 (2015-10-03) Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles.Krishnamoorthy Sreenivasan et al.Cell reports, 31(7), 107652-107652 (2020-05-21) Reply to P.G. Tsoutsou et al, o. Kaidar-Person et al, and A. Courdi et al.Kevin S Hughes et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(36), 4571-4573 (2013-11-06) Autoreactive T cells induce necrosis and not BCL-2-regulated or death receptor-mediated apoptosis or RIPK3-dependent necroptosis of transplanted islets in a mouse model of type 1 diabetes.Yuxing Zhao et al.Diabetologia, 58(1), 140-148 (2014-10-11) Combined estrogenic and anti-estrogenic properties of estetrol on breast cancer may provide a safe therapeutic window for the treatment of menopausal symptoms.Céline Gérard et al.Oncotarget, 6(19), 17621-17636 (2015-06-10) Investigating the allosteric reverse signalling of PARP inhibitors with microsecond molecular dynamic simulations and fluorescence anisotropy.Jean-Rémy Marchand et al.Biochimica et biophysica acta, 1844(10), 1765-1772 (2014-07-27) Plasticity of Hopx(+) type I alveolar cells to regenerate type II cells in the lung.Rajan Jain et al.Nature communications, 6, 6727-6727 (2015-04-14) Expression of DNMT1 in neural stem/precursor cells is critical for survival of newly generated neurons in the adult hippocampus.Hirofumi Noguchi et al.Neuroscience research, 95, 1-11 (2015-02-11) Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations during Wound Healing.Simon Joost et al.Cell reports, 25(3), 585-597 (2018-10-18) Exploring the origin and limitations of kidney regeneration.Tomomi Endo et al.The Journal of pathology, 236(2), 251-263 (2015-02-11) Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex.Ning Liang et al.The Journal of experimental medicine, 211(11), 2249-2263 (2014-10-08) Type 2 Fibroblast Growth Factor Receptor Signaling Preserves Stemness and Prevents Differentiation of Prostate Stem Cells from the Basal Compartment.Yanqing Huang et al.The Journal of biological chemistry, 290(29), 17753-17761 (2015-06-03) Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.Markus A Lill et al.Journal of medicinal chemistry, 48(18), 5666-5674 (2005-09-02) Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination.Zhangguo Chen et al.Journal of immunology (Baltimore, Md. : 1950), 195(11), 5461-5471 (2015-10-27) Novel selective estrogen mimics for the treatment of tamoxifen-resistant breast cancer.Mary Ellen Molloy et al.Molecular cancer therapeutics, 13(11), 2515-2526 (2014-09-11) Thrombospondin-1 repression is mediated via distinct mechanisms in fibroblasts and epithelial cells.R S Watnick et al.Oncogene, 34(22), 2823-2835 (2014-08-12) Pou4f1 Defines a Subgroup of Type I Spiral Ganglion Neurons and Is Necessary for Normal Inner Hair Cell Presynaptic Ca2+ Signaling.Hanna E Sherrill et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(27), 5284-5298 (2019-05-16) TMEM100 is a key factor for specification of lymphatic endothelial progenitors.Eun-Hye Moon et al.Angiogenesis, 23(3), 339-355 (2020-03-01) Modeling the specific CD4+ T cell response against a tumor neoantigen.Héloïse Flament et al.Journal of immunology (Baltimore, Md. : 1950), 194(7), 3501-3512 (2015-03-04) Germ cell nuclear factor regulates gametogenesis in developing gonads.Davood Sabour et al.PloS one, 9(8), e103985-e103985 (2014-08-21) 5-Azacytidine Potentiates Anti-tumor Immunity in a Model of Pancreatic Ductal Adenocarcinoma.Nancy D Ebelt et al.Frontiers in immunology, 11, 538-538 (2020-04-17) Role of GPR30 in mediating estradiol effects on acetylcholine release in the hippocampus.R B Gibbs et al.Hormones and behavior, 66(2), 339-345 (2014-06-15) Reactive cholangiocytes differentiate into proliferative hepatocytes with efficient DNA repair in mice with chronic liver injury.Rita Manco et al.Journal of hepatology, 70(6), 1180-1191 (2019-02-23) Specific loss of adipocyte CD248 improves metabolic health via reduced white adipose tissue hypoxia, fibrosis and inflammation.Paul Petrus et al.EBioMedicine, 44, 489-501 (2019-06-22) Cardiomyocyte cyclooxygenase-2 influences cardiac rhythm and function.Dairong Wang et al.Proceedings of the National Academy of Sciences of the United States of America, 106(18), 7548-7552 (2009-04-21) Genomic action of permanently charged tamoxifen derivatives via estrogen receptor-alpha.Claudia Rivera-Guevara et al.Bioorganic & medicinal chemistry, 18(15), 5593-5601 (2010-07-14) Gastric squamous-columnar junction contains a large pool of cancer-prone immature osteopontin responsive Lgr5-CD44+ cells.Dah-Jiun Fu et al.Nature communications, 11(1), 84-84 (2020-01-05) Ca2+ signalling behaviours of intramuscular interstitial cells of Cajal in the murine colon.Bernard T Drumm et al.The Journal of physiology, 597(14), 3587-3617 (2019-05-28) Combinatorial therapy with tamoxifen and trifluoperazine effectively inhibits malignant peripheral nerve sheath tumor growth by targeting complementary signaling cascades.Stephanie N Brosius et al.Journal of neuropathology and experimental neurology, 73(11), 1078-1090 (2014-10-08) Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.Anne E Powell et al.American journal of physiology. Gastrointestinal and liver physiology, 307(1), G16-G23 (2014-05-17) Characterization of transgenic mouse lines for labeling type I and type II afferent neurons in the cochlea.Pankhuri Vyas et al.Scientific reports, 9(1), 5549-5549 (2019-04-05) Selective oestrogen receptor (ER) modulators reduce microglia reactivity in vivo after peripheral inflammation: potential role of microglial ERs.Silvia Tapia-Gonzalez et al.The Journal of endocrinology, 198(1), 219-230 (2008-05-08) Interpreting the CYP2D6 results from the International Tamoxifen Pharmacogenetics Consortium.M A Province et al.Clinical pharmacology and therapeutics, 96(2), 144-146 (2014-07-25) Acquisition of a Unique Mesenchymal Precursor-like Blastema State Underlies Successful Adult Mammalian Digit Tip Regeneration.Mekayla A Storer et al.Developmental cell, 52(4), 509-524 (2020-01-07) Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice.Wei-Wen Lim et al.PloS one, 15(1), e0227505-e0227505 (2020-01-10) Oncogenic G Protein GNAQ Induces Uveal Melanoma and Intravasation in Mice.Jenny Li-Ying Huang et al.Cancer research, 75(16), 3384-3397 (2015-06-27) Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression.Timothy Marsh et al.Developmental cell, 52(5), 591-604 (2020-02-23) ERK1 and ERK2 regulate chondrocyte terminal differentiation during endochondral bone formation.Zhijun Chen et al.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 30(5), 765-774 (2014-11-18) HNF4 Regulates Fatty Acid Oxidation and Is Required for Renewal of Intestinal Stem Cells in Mice.Lei Chen et al.Gastroenterology, 158(4), 985-999 (2019-11-25) TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment.Yun Li et al.Neuron, 59(3), 399-412 (2008-08-15) Tyrosine phosphatase Shp2 mediates the estrogen biological action in breast cancer via interaction with the estrogen extranuclear receptor.Li J, Kang Y, Wei L, et al. PLoS ONE, 9(7), e102847-e102847 (2014) A predictive ligand-based Bayesian model for human drug-induced liver injury.Sean Ekins et al.Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2302-2308 (2010-09-17) Sox17 is required for endothelial regeneration following inflammation-induced vascular injury.Menglin Liu et al.Nature communications, 10(1), 2126-2126 (2019-05-11) G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer.Kaitlyn J Andreano et al.Breast cancer research and treatment, 180(3), 635-646 (2020-03-05) Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells.Yuxuan Miao et al.Cell, 177(5), 1172-1186 (2019-04-30) Application of the McMurry coupling reaction in the synthesis of tri- and tetra-arylethylene analogues as potential cancer chemotherapeutic agents.Rajendra P Tanpure et al.Bioorganic & medicinal chemistry, 17(19), 6993-7001 (2009-09-08) Distinct cellular origin and genetic requirement of Hedgehog-Gli in postnatal rhabdomyosarcoma genesis.M Rajurkar et al.Oncogene, 33(46), 5370-5378 (2013-11-28) Rapid generation of inducible mouse mutants.Jost Seibler et al.Nucleic acids research, 31(4), e12-e12 (2003-02-13) HOXB5 Promotes the Proliferation and Invasion of Breast Cancer Cells.Ji-Yeon Lee et al.International journal of biological sciences, 11(6), 701-711 (2015-05-23) Kindlin-3-mediated integrin adhesion is dispensable for quiescent but essential for activated hematopoietic stem cells.Raphael Ruppert et al.The Journal of experimental medicine, 212(9), 1415-1432 (2015-08-19) Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor.Erxia Shen et al.Cell reports, 29(7), 1848-1861 (2019-11-14) Evaluation of endocrine activities of ellagic acid and urolithins using reporter gene assays.Darja Gramec Skledar et al.Chemosphere, 220, 706-713 (2019-01-06) Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes.Jeremie Boucher et al.Proceedings of the National Academy of Sciences of the United States of America, 111(40), 14512-14517 (2014-09-24) A systematic review and methodological evaluation of published cost-effectiveness analyses of aromatase inhibitors versus tamoxifen in early stage breast cancer.Ava A John-Baptiste et al.PloS one, 8(5), e62614-e62614 (2013-05-15) AVE protein expression and visceral endoderm cell behavior during anterior-posterior axis formation in mouse embryos: Asymmetry in OTX2 and DKK1 expression.Hideharu Hoshino et al.Developmental biology, 402(2), 175-191 (2015-04-26) Mga is essential for the survival of pluripotent cells during peri-implantation development.Andrew J Washkowitz et al.Development (Cambridge, England), 142(1), 31-40 (2014-12-18) IKKβ slows Huntington's disease progression in R6/1 mice.Joseph Ochaba et al.Proceedings of the National Academy of Sciences of the United States of America, 116(22), 10952-10961 (2019-05-16) Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling.Mayank Verma et al.Cell stem cell, 23(4), 530-543 (2018-10-06) Pancreatic cancer triggers diabetes through TGF-β-mediated selective depletion of islet β-cells.Parash Parajuli et al.Life science alliance, 3(6) (2020-05-07) Circulating FABP4 is eliminated by the kidney via glomerular filtration followed by megalin-mediated reabsorption.Suman Shrestha et al.Scientific reports, 8(1), 16451-16451 (2018-11-08) Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination.Zhangguo Chen et al.Journal of immunology (Baltimore, Md. : 1950), 195(11), 5461-5471 (2015-10-27) Novel selective estrogen mimics for the treatment of tamoxifen-resistant breast cancer.Mary Ellen Molloy et al.Molecular cancer therapeutics, 13(11), 2515-2526 (2014-09-11) Thrombospondin-1 repression is mediated via distinct mechanisms in fibroblasts and epithelial cells.R S Watnick et al.Oncogene, 34(22), 2823-2835 (2014-08-12) Pou4f1 Defines a Subgroup of Type I Spiral Ganglion Neurons and Is Necessary for Normal Inner Hair Cell Presynaptic Ca2+ Signaling.Hanna E Sherrill et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(27), 5284-5298 (2019-05-16) Licensing of primordial germ cells for gametogenesis depends on genital ridge signaling.Yueh-Chiang Hu et al.PLoS genetics, 11(3), e1005019-e1005019 (2015-03-05) Angiopoietin-2 exacerbates cardiac hypoxia and inflammation after myocardial infarction.Seung-Jun Lee et al.The Journal of clinical investigation, 128(11), 5018-5033 (2018-10-09) Two-gene expression ratio as predictor for breast cancer treated with tamoxifen: evidence from meta-analysis.Lin Zhao et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(4), 3113-3117 (2013-11-23) Development and characterization of an inducible Dicer conditional knockout mouse model of Parkinson's disease: validation of the antiparkinsonian effects of a sigma-1 receptor agonist and dihydromyricetin.Chen-Hong Guo et al.Acta pharmacologica Sinica, 41(4), 499-507 (2020-03-01) Breakthrough in ER+ breast cancer. Specific gene's shutdown is detectable in blood; indicates cancer cell vulnerability, thus enabling earlier treatment. DukeMedicine healthnews, 19(10), 7-7 (2013-12-03) TNAP limits TGF-β-dependent cardiac and skeletal muscle fibrosis by inactivating the SMAD2/3 transcription factors.Benedetta Arnò et al.Journal of cell science, 132(15) (2019-07-11) Tumor Suppressor NF2 Blocks Cellular Migration by Inhibiting Ectodomain Cleavage of CD44.Monika Hartmann et al.Molecular cancer research : MCR, 13(5), 879-890 (2015-02-06) Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis.Maximilian Strunz et al.Nature communications, 11(1), 3559-3559 (2020-07-18) Overexpression of PKCalpha is required to impart estradiol inhibition and tamoxifen-resistance in a T47D human breast cancer tumor model.Xin Lin et al.Carcinogenesis, 27(8), 1538-1546 (2006-03-04) Progressive disorganization of paranodal junctions and compact myelin due to loss of DCC expression by oligodendrocytes.Sarah-Jane Bull et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(29), 9768-9778 (2014-07-18) BIK drives an aggressive breast cancer phenotype through sublethal apoptosis and predicts poor prognosis of ER-positive breast cancer.Vrajesh Pandya et al.Cell death & disease, 11(6), 448-448 (2020-06-13) Genetic targeting of sprouting angiogenesis using Apln-CreER.Qiaozhen Liu et al.Nature communications, 6, 6020-6020 (2015-01-20) TTBK2 and primary cilia are essential for the connectivity and survival of cerebellar Purkinje neurons.Emily Bowie et al.eLife, 9 (2020-01-15) Age-Dependent Remarkable Regenerative Potential of the Dentate Gyrus Provided by Intrinsic Stem Cells.Tamar Licht et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(5), 974-995 (2020-01-22) Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex.Brian G Coon et al.The Journal of cell biology, 208(7), 975-986 (2015-03-25) Genetic dissection of the vav2-rac1 signaling axis in vascular smooth muscle cells.Salvatore Fabbiano et al.Molecular and cellular biology, 34(24), 4404-4419 (2014-10-08) Requirement for interaction of PI3-kinase p110α with RAS in lung tumor maintenance.Esther Castellano et al.Cancer cell, 24(5), 617-630 (2013-11-16) Myh11+ microvascular mural cells and derived mesenchymal stem cells promote retinal fibrosis.H Clifton Ray et al.Scientific reports, 10(1), 15808-15808 (2020-09-27) Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis.T Liu et al.Cell death & disease, 5, e1470-e1470 (2014-10-17) Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap.Sylvia T Nurnberg et al.PLoS genetics, 11(5), e1005155-e1005155 (2015-05-29) Loss of Setd4 delays radiation-induced thymic lymphoma in mice.Xing Feng et al.DNA repair, 86, 102754-102754 (2019-12-04) Switching of Sox9 expression during musculoskeletal system development.Ryotaro Nagakura et al.Scientific reports, 10(1), 8425-8425 (2020-05-23) IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation.Sun-Mi Park et al.Cell stem cell, 24(1), 153-165 (2018-11-26) Angiopoietin-2 exacerbates cardiac hypoxia and inflammation after myocardial infarction.Seung-Jun Lee et al.The Journal of clinical investigation, 128(11), 5018-5033 (2018-10-09) Two-gene expression ratio as predictor for breast cancer treated with tamoxifen: evidence from meta-analysis.Lin Zhao et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(4), 3113-3117 (2013-11-23) Development and characterization of an inducible Dicer conditional knockout mouse model of Parkinson's disease: validation of the antiparkinsonian effects of a sigma-1 receptor agonist and dihydromyricetin.Chen-Hong Guo et al.Acta pharmacologica Sinica, 41(4), 499-507 (2020-03-01) Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.Nidhi Puri et al.European journal of medicinal chemistry, 45(11), 4813-4826 (2010-08-27) Stage-dependent and locus-specific role of histone demethylase Jumonji D3 (JMJD3) in the embryonic stages of lung development.Qingtian Li et al.PLoS genetics, 10(7), e1004524-e1004524 (2014-08-01) AVE protein expression and visceral endoderm cell behavior during anterior-posterior axis formation in mouse embryos: Asymmetry in OTX2 and DKK1 expression.Hideharu Hoshino et al.Developmental biology, 402(2), 175-191 (2015-04-26) Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium.Katja Horvay et al.The EMBO journal, 34(10), 1319-1335 (2015-03-12) The small GTPases RhoA and Rac1 regulate cerebellar development by controlling cell morphogenesis, migration and foliation.Shalaka Mulherkar et al.Developmental biology, 394(1), 39-53 (2014-08-17) RCAD/Ufl1, a Ufm1 E3 ligase, is essential for hematopoietic stem cell function and murine hematopoiesis.M Zhang et al.Cell death and differentiation, 22(12), 1922-1934 (2015-05-09) [Diagnosis of ductal carcinoma in situ with interruption of the anterior border of the mammary gland by ultrasonography-a case report].Kenichi Sakurai et al.Gan to kagaku ryoho. Cancer & chemotherapy, 40(12), 2360-2362 (2014-01-08) Intestinal epithelial HuR modulates distinct pathways of proliferation and apoptosis and attenuates small intestinal and colonic tumor development.Giammanco A, Blanc V, Montenegro G, et al. Cancer Research, 74(18), 5322-5335 (2014) Dynamics of Asymmetric and Symmetric Divisions of Muscle Stem Cells In Vivo and on Artificial Niches.Brendan Evano et al.Cell reports, 30(10), 3195-3206 (2020-03-12) Development of Resistance to EGFR-Targeted Therapy in Malignant Glioma Can Occur through EGFR-Dependent and -Independent Mechanisms.Stefan Klingler et al.Cancer research, 75(10), 2109-2119 (2015-03-27) Switching of Sox9 expression during musculoskeletal system development.Ryotaro Nagakura et al.Scientific reports, 10(1), 8425-8425 (2020-05-23) In vitro and in vivo anticancer activity of 2-deacetoxytaxinine J and synthesis of novel taxoids and their in vitro anticancer activity.K Papi Reddy et al.European journal of medicinal chemistry, 44(10), 3947-3953 (2009-05-19) In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.Holger Fischer et al.Journal of medicinal chemistry, 55(1), 126-139 (2011-11-30) Sirt1 restrains lung inflammasome activation in a murine model of sepsis.Rong Gao et al.American journal of physiology. Lung cellular and molecular physiology, 308(8), L847-L853 (2015-02-11) SHP2 regulates chondrocyte terminal differentiation, growth plate architecture and skeletal cell fates.Margot E Bowen et al.PLoS genetics, 10(5), e1004364-e1004364 (2014-05-31) [Tamoxifen treatment and pulmunary embolism: a case report and literature review].Gregoriana Zanini et al.Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 80(1), 42-44 (2013-08-09) Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight.Giacomo Mancini et al.Cell reports, 26(11), 2849-2858 (2019-03-14) Regulation of the pentose phosphate pathway by an androgen receptor-mTOR-mediated mechanism and its role in prostate cancer cell growth.E Tsouko et al.Oncogenesis, 3, e103-e103 (2014-05-28) Differential Roles of IL-2 Signaling in Developing versus Mature Tregs.Martin Y Fan et al.Cell reports, 25(5), 1204-1213 (2018-11-01) Survival and maintenance of regulatory T cells require the kinase TAK1.Jae-Hoon Chang et al.Cellular & molecular immunology, 12(5), 572-579 (2015-04-22) Expression Patterns of Inducible Cre Recombinase Driven by Differential Astrocyte-Specific Promoters in Transgenic Mouse Lines.Neng-Yuan Hu et al.Neuroscience bulletin, 36(5), 530-544 (2019-12-13) Experts add second drug to breast cancer prevention regimen. Harvard women's health watch, 21(2), 8-8 (2014-01-18) Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy.Marcelo A Mori et al.The Journal of clinical investigation, 124(8), 3339-3351 (2014-07-02) Myh11+ microvascular mural cells and derived mesenchymal stem cells promote retinal fibrosis.H Clifton Ray et al.Scientific reports, 10(1), 15808-15808 (2020-09-27) Chemotherapeutic effect of tamoxifen on temozolomide-resistant gliomas.Weiliang He et al.Anti-cancer drugs, 26(3), 293-300 (2014-12-24) Profound reduction in the tamoxifen active metabolite endoxifen in a patient on phenytoin for epilepsy compared with a CYP2D6 genotype matched cohort.Steven E Gryn et al.Pharmacogenetics and genomics, 24(7), 367-369 (2014-06-11) Nutrient Sensing by the Intestinal Epithelium Orchestrates Mucosal Antimicrobial Defense via Translational Control of Hes1.Shaonan Liang et al.Cell host & microbe, 25(5), 706-718 (2019-05-06) Chondrocytes transdifferentiate into osteoblasts in endochondral bone during development, postnatal growth and fracture healing in mice.Xin Zhou et al.PLoS genetics, 10(12), e1004820-e1004820 (2014-12-05) RalGTPases contribute to Schwann cell repair after nerve injury via regulation of process formation.Jorge Galino et al.The Journal of cell biology, 218(7), 2370-2387 (2019-06-16) Identification of a series of tetrahydroisoquinoline derivatives as potential therapeutic agents for breast cancer.Hsiang-Ru Lin et al.Bioorganic & medicinal chemistry letters, 17(9), 2581-2589 (2007-03-06) IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation.Sun-Mi Park et al.Cell stem cell, 24(1), 153-165 (2018-11-26) BIK drives an aggressive breast cancer phenotype through sublethal apoptosis and predicts poor prognosis of ER-positive breast cancer.Vrajesh Pandya et al.Cell death & disease, 11(6), 448-448 (2020-06-13) Genetic targeting of sprouting angiogenesis using Apln-CreER.Qiaozhen Liu et al.Nature communications, 6, 6020-6020 (2015-01-20) Aromatase induction in tamoxifen-resistant breast cancer: Role of phosphoinositide 3-kinase-dependent CREB activation.Nguyen Thi Thuy Phuong et al.Cancer letters, 351(1), 91-99 (2014-05-20) Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung.Lisandra Vila Ellis et al.Developmental cell, 52(5), 617-630 (2020-02-16) Microglial microRNAs mediate sex-specific responses to tau pathology.Lay Kodama et al.Nature neuroscience, 23(2), 167-171 (2019-12-25) Loss of Hap1 selectively promotes striatal degeneration in Huntington disease mice.Qiong Liu et al.Proceedings of the National Academy of Sciences of the United States of America, 117(33), 20265-20273 (2020-08-05) Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium.Katja Horvay et al.The EMBO journal, 34(10), 1319-1335 (2015-03-12) [Successful treatment of neuroendocrine ductal carcinoma in situ with loco-regional therapy].Kenichi Sakurai et al.Gan to kagaku ryoho. Cancer & chemotherapy, 40(12), 2363-2365 (2014-01-08) Lymphatics in bone arise from pre-existing lymphatics.Marco Monroy et al.Development (Cambridge, England), 147(21) (2020-03-20) Nfil3-independent lineage maintenance and antiviral response of natural killer cells.Matthew A Firth et al.The Journal of experimental medicine, 210(13), 2981-2990 (2013-11-28) Identification and structure-activity relationships of chromene-derived selective estrogen receptor modulators for treatment of postmenopausal symptoms.Nareshkumar Jain et al.Journal of medicinal chemistry, 52(23), 7544-7569 (2009-04-16) Cholesterol metabolism and resistance to tamoxifen.Marc Poirot et al.Current opinion in pharmacology, 12(6), 683-689 (2012-10-16) Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation.Liu Yang et al.Proceedings of the National Academy of Sciences of the United States of America, 111(33), 12097-12102 (2014-08-06) Lymphatics in bone arise from pre-existing lymphatics.Marco Monroy et al.Development (Cambridge, England), 147(21) (2020-03-20) In vitro cytotoxicity and bioavailability of solid lipid nanoparticles containing tamoxifen citrate.Fahima M Hashem et al.Pharmaceutical development and technology, 19(7), 824-832 (2013-09-17) The multicopper ferroxidase hephaestin enhances intestinal iron absorption in mice.Brie K Fuqua et al.PloS one, 9(6), e98792-e98792 (2014-06-05) Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging.Liana R Stein et al.The EMBO journal, 33(12), 1321-1340 (2014-05-09) Symptoms and cancer outcome in adjuvant endocrine therapy for breast cancer: why are they associated?Kathleen I Pritchard Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(35), 4476-4476 (2013-11-06) Fgd5 identifies hematopoietic stem cells in the murine bone marrow.Roi Gazit et al.The Journal of experimental medicine, 211(7), 1315-1331 (2014-06-25) Haematopoietic focal adhesion kinase deficiency alters haematopoietic homeostasis to drive tumour metastasis.Silvia Batista et al.Nature communications, 5, 5054-5054 (2014-10-02) GATA3 in the urinary bladder: suppression of neoplastic transformation and down-regulation by androgens.Yi Li et al.American journal of cancer research, 4(5), 461-473 (2014-09-19) YAP and TAZ protect against white adipocyte cell death during obesity.Lei Wang et al.Nature communications, 11(1), 5455-5455 (2020-10-30) Histone deacetylase inhibitor treatment induces 'BRCAness' and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells.Kyungsoo Ha et al.Oncotarget, 5(14), 5637-5650 (2014-07-16) Locating the binding sites of antitumor drug tamoxifen and its metabolites with DNA.P Bourassa et al.Journal of pharmaceutical and biomedical analysis, 95, 193-199 (2014-04-01) Notch regulation of myogenic versus endothelial fates of cells that migrate from the somite to the limb.Alicia Mayeuf-Louchart et al.Proceedings of the National Academy of Sciences of the United States of America, 111(24), 8844-8849 (2014-06-14) Retinal microangiopathy in a mouse model of inducible mural cell loss.Cammi N Valdez et al.The American journal of pathology, 184(10), 2618-2626 (2014-08-06)

备注