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The Effects of Silymarin and Cyclosporine A on the Proliferation and Cytokine Production of Regulatory T Cells.Niloufar Keyhanmehr et al.Immunological investigations, 48(5), 533-548 (2019-04-06) Protective effects of silymarin on fumonisin B1-induced hepatotoxicity in miceSozmen M, et al. Journal of Veterinary Science, 15(1), 51-60 (2012) Multitargeted therapy of cancer by silymarinRamasamy K and Agarwal R Cancer letters, 269(2), 352-362 (2008) Silymarin suppresses HepG2 hepatocarcinoma cell progression through downregulation of Slit-2/Robo-1 pathway.Nuriye Ezgi Bektur Aykanat et al.Pharmacological reports : PR, 72(1), 199-207 (2020-02-06) Pyrroloquinoline-quinone suppresses liver fibrogenesis in mice.Dongwei Jia et al.PloS one, 10(3), e0121939-e0121939 (2015-03-31) Silymarin protects against renal injury through normalization of lipid metabolism and mitochondrial biogenesis in high fat-fed mice.Bin Feng et al.Free radical biology & medicine, 110, 240-249 (2017-06-20) Silymarin protects against radiocontrast-induced nephropathy in mice.Verônica de Souza Santos et al.Life sciences, 228, 305-315 (2019-05-03) Improvement of hyperglycemia in a murine model of insulin resistance and high glucose- and inflammasome-mediated IL-1β expressions in macrophages by silymarin.Chun-Ping Lu et al.Chemico-biological interactions, 290, 12-18 (2018-05-14) Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acidsOzccelik B, et al. Pharmaceutical biology, 49(4), 396-402 (2011) Silymarin Restores Regulatory T Cells (Tregs) Function in Multiple Sclerosis (MS) Patients In Vitro.Maryam Shariati et al.Inflammation, 42(4), 1203-1214 (2019-02-27) In vitro effects on biofilm viability and antibacterial and antiadherent activities of silymarin.Ebru Evren et al.Folia microbiologica, 60(4), 351-356 (2015-05-06) Silymarin protects liver against toxic effects of anti-tuberculosis drugs in experimental animals.Eminzade, S. Nutrition & Metabolism, 5, 18-18 (2008) Formulation of Nanomicelles to Improve the Solubility and the Oral Absorption of Silymarin.Vieri Piazzini et al.Molecules (Basel, Switzerland), 24(9) (2019-05-06) Effect of silymarin on bladder overactivity in cyclophosphamide-induced cystitis rat modelEser N, et al. Phytomedicine, 19(8-9), 840-845 (2012) Sirajudheen Anwar et al.Indian journal of pharmacology, 50(3), 108-115 (2018-09-01)Silymarin, extracted from the seeds of Silybum marianum L. (Milk thistle), is traditionally used for treating various illnesses such as diabetes, cancer, inflammation, hepatitis, liver cirrhosis, and renal problems. Acute cytotoxicity and genotoxicity studies have been reported with ambiguous outcomes;...

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