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trans-1,4-Diaminocyclohexane | CAS:2615-25-0
trans-1,4-Diaminocyclohexane
  • 名称:反式-1,4-环己二胺 | trans-1,4-Diaminocyclohexane
  • CAS号:2615-25-0
  • 别名:1,4-Cyclohexanediamine; trans-1,4-Cyclohexyldiamine
  • 分子式:C6H14N2
  • 分子量:114.19
  • EINESC号:

产品描述

物理化学性质

熔点 68-71 ºC (lit.)
沸点 197 ºC (lit.)
闪点 71 ºC

安全数据

危险品标志 C
危险类别码 R20/21/22;R34
安全说明书 S26;S36/37/39;S45

SDS

来源 SDS样本
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A, 996(1-2), 233-237 (2003-07-02) Non-antiepileptic drugs for trigeminal neuralgia.Mi Yang et al.The Cochrane database of systematic reviews, (1)(1), CD004029-CD004029 (2011-01-21) 2D- and 3D-QSAR of tocainide and mexiletine analogues acting as Na(v)1.4 channel blockers.Antonio Carrieri et al.European journal of medicinal chemistry, 44(4), 1477-1485 (2008-11-26) Constrained analogues of tocainide as potent skeletal muscle sodium channel blockers towards the development of antimyotonic agents.Alessia Catalano et al.European journal of medicinal chemistry, 43(11), 2535-2540 (2008-03-18) Effects of a new potent analog of tocainide on hNav1.7 sodium channels and in vivo neuropathic pain models.C Ghelardini et al.Neuroscience, 169(2), 863-873 (2010-06-29) Searching for novel anti-myotonic agents: pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide.Annamaria De Luca et al.Neuromuscular disorders : NMD, 22(1), 56-65 (2011-08-02) Increased rigidity of the chiral centre of tocainide favours stereoselectivity and use-dependent block of skeletal muscle Na(+) channels enhancing the antimyotonic activity in vivo.S Talon et al.British journal of pharmacology, 134(7), 1523-1531 (2001-11-29) Chemistry, pharmacology, antiarrhythmic efficacy and adverse effects of tocainide hydrochloride, an orally active structural analog of lidocaine.J S Alpert et al.Pharmacotherapy, 3(6), 316-323 (1983-11-01) Treatment of tinnitus with tocainide hydrochloride.J R Emmett et al.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 88(4), 442-446 (1980-07-01) High-speed chiral separations on a microchip with UV detection.Martin Ludwig et al.Electrophoresis, 24(18), 3233-3238 (2003-10-01) Systemic administration of local anesthetic agents to relieve neuropathic pain.V Challapalli et al.The Cochrane database of systematic reviews, (4)(4), CD003345-CD003345 (2005-10-20) Photochemical and chemical oxidation of mexiletine and tocainide. 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