询 单
请 填 写 相 关 信 息
产品信息
产品名称
别名
CAS号
结构式 上传
联系方式
公司
联系人
电话
邮箱
内容
提交
中文版 English
请输入产品名称、CAS式、分子式
(3beta,7beta,17beta)-Androst-5-ene-3,7,17-triol | CAS:2697-85-0
(3beta,7beta,17beta)-Androst-5-ene-3,7,17-triol
  • 名称:(3beta,7beta,17beta)-雄甾-5-烯-3,7,17-三醇 | (3beta,7beta,17beta)-Androst-5-ene-3,7,17-triol
  • CAS号:2697-85-0
  • 别名:3beta,7beta,17beta-Androst-5-enetriol
  • 分子式:C19H30O3
  • 分子量:306.44
  • EINESC号:

产品描述

物理化学性质

熔点 235-237 ºC**
密度 1.19±0.1 g/cm3 (20 ºC

安全数据

没有数据没有数据

SDS

来源 SDS样本
没有数据没有数据
产品合成路线
更多

名称 CAS号
更多
文章
同行评议文献
SINC, a type III secreted protein of Chlamydia psittaci, targets the inner nuclear membrane of infected cells and uninfected neighbors.Sergio A Mojica et al.Molecular biology of the cell, 26(10), 1918-1934 (2015-03-20) Common γ-chain cytokine signaling is required for macroautophagy induction during CD4+ T-cell activation.Yair Botbol et al.Autophagy, 11(10), 1864-1877 (2015-09-24) Structural insight into BH3 domain binding of vaccinia virus antiapoptotic F1L.Stephanie Campbell et al.Journal of virology, 88(15), 8667-8677 (2014-05-23) A gene to organism approach--assessing the impact of environmental pollution in eelpout (Zoarces viviparus) females and larvae.Noomi Asker et al.Environmental toxicology and chemistry, 34(7), 1511-1523 (2015-02-11) Multiple ecto-nucleoside triphosphate diphosphohydrolases facilitate intracellular replication of Legionella pneumophila.Patrice Riedmaier et al.The Biochemical journal, 462(2), 279-289 (2014-06-25) CpG ODNs induced autophagy via reactive oxygen species (ROS) in Chinese mitten crab, Eriocheir sinensis.Mingzhe Sun et al.Developmental and comparative immunology, 52(1), 1-9 (2015-04-29) Cationic Polyrotaxanes as a Feasible Framework for the Intracellular Delivery and Sustainable Activity of Anionic Enzymes: A Comparison Study with Methacrylate-Based Polycations.Atsushi Tamura et al.Macromolecular bioscience, 15(8), 1134-1145 (2015-04-30) P2X7 mediates ATP-driven invasiveness in prostate cancer cells.Ying Qiu et al.PloS one, 9(12), e114371-e114371 (2014-12-09) Nuclear exportin receptor CAS regulates the NPI-1-mediated nuclear import of HIV-1 Vpr.Eri Takeda et al.PloS one, 6(11), e27815-e27815 (2011-11-24) FTT0831c/FTL_0325 contributes to Francisella tularensis cell division, maintenance of cell shape, and structural integrity.Gregory T Robertson et al.Infection and immunity, 82(7), 2935-2948 (2014-04-30) A conserved motif in the linker domain of STAT1 transcription factor is required for both recognition and release from high-affinity DNA-binding sites.Bettina Hüntelmann et al.PloS one, 9(5), e97633-e97633 (2014-05-23) Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation.K Kluckova et al.Cell death & disease, 6, e1749-e1749 (2015-05-08) Meta-analyses of Dehalococcoides mccartyi strain 195 transcriptomic profiles identify a respiration rate-related gene expression transition point and interoperon recruitment of a key oxidoreductase subunit.Cresten B Mansfeldt et al.Applied and environmental microbiology, 80(19), 6062-6072 (2014-07-27) A megacomplex composed of both photosystem reaction centres in higher plants.M Yokono et al.Nature communications, 6, 6675-6675 (2015-03-27) Osmosensing and scaffolding functions of the oligomeric four-transmembrane domain osmosensor Sho1.Kazuo Tatebayashi et al.Nature communications, 6, 6975-6975 (2015-04-22) Lipopolysaccharide induces neuroinflammation in microglia by activating the MTOR pathway and downregulating Vps34 to inhibit autophagosome formation.Xiaoxia Ye et al.Journal of neuroinflammation, 17(1), 18-18 (2020-01-14) Membrane-bound trafficking regulates nuclear transport of integral epidermal growth factor receptor (EGFR) and ErbB-2.Ying-Nai Wang et al.The Journal of biological chemistry, 287(20), 16869-16879 (2012-03-28) Clinical relevance of voltage-gated potassium channel–complex antibodies in children.Yael Hacohen et al.Neurology, 85(11), 967-975 (2015-08-25) The landscape of RNA Pol II binding reveals a stepwise transition during ZGA.Bofeng Liu et al.Nature, 587(7832), 139-144 (2020-10-30) Identification and characterization of a nuclear localization signal of TRIM28 that overlaps with the HP1 box.Tetsuji Moriyama et al.Biochemical and biophysical research communications, 462(3), 201-207 (2015-05-12) Studies of OC-STAMP in Osteoclast Fusion: A New Knockout Mouse Model, Rescue of Cell Fusion, and Transmembrane Topology.Hanna Witwicka et al.PloS one, 10(6), e0128275-e0128275 (2015-06-05) Chemical Response of the Toxic Dinoflagellate Karenia mikimotoi Against Grazing by Three Species of Zooplankton.Lin-Xi Dang et al.The Journal of eukaryotic microbiology, 62(4), 470-480 (2014-12-20) Macrophage mitochondrial and stress response to ingestion of Cryptococcus neoformans.Carolina Coelho et al.Journal of immunology (Baltimore, Md. : 1950), 194(5), 2345-2357 (2015-02-04) Significance of expression of glucagon-like peptide 1 receptor in pancreatic cancer.Ana Ines Cases et al.Oncology reports, 34(4), 1717-1725 (2015-08-05) Mitochondrial targeting of bilirubin regulatory enzymes: An adaptive response to oxidative stress.Siti Nur Fadzilah Muhsain et al.Toxicology and applied pharmacology, 282(1), 77-89 (2014-12-06) Sulforaphane alleviates muscular dystrophy in mdx mice by activation of Nrf2.Chengcao Sun et al.Journal of applied physiology (Bethesda, Md. : 1985), 118(2), 224-237 (2015-01-17) Latency of peroxisomal palmitoyl-CoA beta-oxidation in digitonin permeabilized fibroblasts: the effect of ATP on peroxisomal permeability.E J Wolvetang et al.Progress in clinical and biological research, 375, 223-229 (1992-01-01) A bacterial type III secretion-based protein delivery tool for broad applications in cell biology.Simon J Ittig et al.The Journal of cell biology, 211(4), 913-931 (2015-11-26) SFTSV Infection Induces BAK/BAX-Dependent Mitochondrial DNA Release to Trigger NLRP3 Inflammasome Activation.Shufen Li et al.Cell reports, 30(13), 4370-4385 (2020-04-03) MCL-1-independent mechanisms of synergy between dual PI3K/mTOR and BCL-2 inhibition in diffuse large B cell lymphoma.J Scott Lee et al.Oncotarget, 6(34), 35202-35217 (2015-10-16) UVA/B exposure promotes the biosynthesis of dehydroretinol in cultured human keratinocytes.Juliana I Tafrova et al.Molecular and cellular biochemistry, 364(1-2), 351-361 (2012-02-07) Wogonin induces apoptosis and endoplasmic reticulum stress in HL-60 leukemia cells through inhibition of the PI3K-AKT signaling pathway.Chengjun Hu et al.Oncology reports, 33(6), 3146-3154 (2015-04-08) Discrimination between Mycoplasma and Acholeplasma species of bovine origin using digitonin disc diffusion assay, nisin disc diffusion assay, and conventional polymerase chain reaction.Sukolrat Boonyayatra et al.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 24(1), 7-13 (2012-03-01) Spatial-fluxomics provides a subcellular-compartmentalized view of reductive glutamine metabolism in cancer cells.Won Dong Lee et al.Nature communications, 10(1), 1351-1351 (2019-03-25) Kinetic evidence against partitioning of the ubiquinone pool and the catalytic relevance of respiratory-chain supercomplexes.James N Blaza et al.Proceedings of the National Academy of Sciences of the United States of America, 111(44), 15735-15740 (2014-10-22) Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins.Dominic S Alonzi et al.Cellular and molecular life sciences : CMLS, 70(15), 2799-2814 (2013-03-19) Characterization of the molecular determinants of primary HIV-1 Vpr proteins: impact of the Q65R and R77Q substitutions on Vpr functions.Guillaume Jacquot et al.PloS one, 4(10), e7514-e7514 (2009-10-20) Granzyme B-activated p53 interacts with Bcl-2 to promote cytotoxic lymphocyte-mediated apoptosis.Thouraya Ben Safta et al.Journal of immunology (Baltimore, Md. : 1950), 194(1), 418-428 (2014-11-19) Cowpox virus protein CPXV012 eludes CTLs by blocking ATP binding to TAP.Rutger D Luteijn et al.Journal of immunology (Baltimore, Md. : 1950), 193(4), 1578-1589 (2014-07-16) Generation of Red-Shifted Cameleons for Imaging Ca²⁺ Dynamics of the Endoplasmic Reticulum.Markus Waldeck-Weiermair et al.Sensors (Basel, Switzerland), 15(6), 13052-13068 (2015-06-09) A Unified Linear Viscoelastic Model of the Cell Nucleus Defines the Mechanical Contributions of Lamins and Chromatin.Oren Wintner et al.Advanced science (Weinheim, Baden-Wurttemberg, Germany), 7(8), 1901222-1901222 (2020-04-25) 4-Nitrobenzaldehyde thiosemicarbazone: a new compound derived from S-(-)-limonene that induces mitochondrial alterations in epimastigotes and trypomastigotes of Trypanosoma cruzi.Elizandra Aparecida Britta et al.Parasitology, 142(7), 978-988 (2015-02-26) Membrane Disintegration Caused by the Steroid Saponin Digitonin Is Related to the Presence of Cholesterol.Ikhwan Resmala Sudji et al.Molecules (Basel, Switzerland), 20(11), 20146-20160 (2015-11-17) Endogenous dopamine is involved in the herbicide paraquat-induced dopaminergic cell death.Yasuhiko Izumi et al.Toxicological sciences : an official journal of the Society of Toxicology, 139(2), 466-478 (2014-04-20) A fine-tuning mechanism underlying self-control for autophagy: deSUMOylation of BECN1 by SENP3.Kejia Liu et al.Autophagy, 16(6), 975-990 (2019-08-03) Identification of Bax-voltage-dependent anion channel 1 complexes in digitonin-solubilized cerebellar granule neurons.Dennis B Huckabee et al.Journal of neurochemistry, 119(5), 1137-1150 (2011-09-29) Synthesis and biological evaluation of biotinyl hydrazone derivatives of muramyl peptides.Didier Blanot et al.Chemical biology & drug design, 79(1), 2-8 (2011-08-06) Translocation of Non-Canonical Polypeptides into Cells Using Protective Antigen.Amy E Rabideau et al.Scientific reports, 5, 11944-11944 (2015-07-17) Substrate modulation of fatty acid effects on energization and respiration of kidney proximal tubules during hypoxia/reoxygenation.Anja Bienholz et al.PloS one, 9(4), e94584-e94584 (2014-04-15) Unravelling the pivotal role of Alix in MVB sorting and silencing of the activated EGFR.Sheng Sun et al.The Biochemical journal, 466(3), 475-487 (2014-12-17) Cooperation of endothelin-1 signaling with melanosomes plays a role in developing and/or maintaining human skin hyperpigmentation.Daiki Murase et al.Biology open, 4(10), 1213-1221 (2015-09-06) MICU1 Confers Protection from MCU-Dependent Manganese Toxicity.Jennifer Wettmarshausen et al.Cell reports, 25(6), 1425-1435 (2018-11-08) [IP3-sensitive Ca(2+)-channels of endoplasmic reticulum in secretory cells of the rat exorbital lacrimal gland].A B Kotliarova et al.Ukrains'kyi biokhimichnyi zhurnal (1999 ), 85(5), 27-36 (2014-02-01) Bovine macrophages sense Escherichia coli Shiga toxin 1.Christian Menge et al.Innate immunity, 21(6), 655-664 (2015-04-25) Accumulation of Nucleolar Inorganic Polyphosphate Is a Cellular Response to Cisplatin-Induced Apoptosis.Lihan Xie et al.Frontiers in oncology, 9, 1410-1410 (2020-01-11) Synergistic interactions of saponins and monoterpenes in HeLa cells, Cos7 cells and in erythrocytes.Florian Herrmann et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(13), 1191-1196 (2011-10-05) Use of digitonin-permeabilized cells in studies of steroid receptor subnuclear trafficking.J Liu et al.Methods (San Diego, Calif.), 19(3), 403-409 (1999-12-02) Regulated IRE1-dependent decay pathway is activated during Japanese encephalitis virus-induced unfolded protein response and benefits viral replication.Sankar Bhattacharyya et al.The Journal of general virology, 95(Pt 1), 71-79 (2013-10-12) Exploring inflammatory disease drug effects on neutrophil function.Xiaojie Wu et al.The Analyst, 139(16), 4056-4063 (2014-06-20) Central role for ferritin in the day/night regulation of iron homeostasis in marine phytoplankton.Hugo Botebol et al.Proceedings of the National Academy of Sciences of the United States of America, 112(47), 14652-14657 (2015-11-11) Human SEIPIN Binds Anionic Phospholipids.Renhong Yan et al.Developmental cell, 47(2), 248-256 (2018-10-09) A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation.Michael L van de Weijer et al.Nature communications, 5, 3832-3832 (2014-05-09) BGLF4 kinase modulates the structure and transport preference of the nuclear pore complex to facilitate nuclear import of Epstein-Barr virus lytic proteins.Chou-Wei Chang et al.Journal of virology, 89(3), 1703-1718 (2014-11-21) A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90.Christopher N J Young et al.Autophagy, 11(1), 113-130 (2015-02-24) Oxidative metabolism in YAC128 mouse model of Huntington's disease.James Hamilton et al.Human molecular genetics, 24(17), 4862-4878 (2015-06-05) Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport.Sreekanth Rajan et al.Scientific reports, 5, 10609-10609 (2015-05-30) Nuclear import of adenovirus DNA involves direct interaction of hexon with an N-terminal domain of the nucleoporin Nup214.Aurélia Cassany et al.Journal of virology, 89(3), 1719-1730 (2014-11-21) A cell model for the initial phase of sporadic Alzheimer's disease.Carola Stockburger et al.Journal of Alzheimer's disease : JAD, 42(2), 395-411 (2014-06-06) Endosomolytic Nano-Polyplex Platform Technology for Cytosolic Peptide Delivery To Inhibit Pathological Vasoconstriction.Brian C Evans et al.ACS nano, 9(6), 5893-5907 (2015-05-26) Labeling of polyethylenimine with fluorescent dye to image nucleus, nucleolus, and chromosomes in digitonin-permeabilized HeLa cells.Masayuki Saito et al.Bioscience, biotechnology, and biochemistry, 76(9), 1777-1780 (2012-09-14) Cytosolic Trypanosoma cruzi nucleoside diphosphate kinase generates large granules that depend on its quaternary structure.Claudio A Pereira et al.Experimental parasitology, 142, 43-50 (2014-04-29) The Ribosome-Sec61 Translocon Complex Forms a Cytosolically Restricted Environment for Early Polytopic Membrane Protein Folding.Melissa A Patterson et al.The Journal of biological chemistry, 290(48), 28944-28952 (2015-08-09) Regulation of callose synthase activity in situ in alamethicin-permeabilized Arabidopsis and tobacco suspension cells.Mari Aidemark et al.BMC plant biology, 9, 27-27 (2009-03-17) LRRC59 Regulates Trafficking of Nucleic Acid-Sensing TLRs from the Endoplasmic Reticulum via Association with UNC93B1.Megumi Tatematsu et al.Journal of immunology (Baltimore, Md. : 1950), 195(10), 4933-4942 (2015-10-16) ERdj5 Reductase Cooperates with Protein Disulfide Isomerase To Promote Simian Virus 40 Endoplasmic Reticulum Membrane Translocation.Takamasa Inoue et al.Journal of virology, 89(17), 8897-8908 (2015-06-19) A novel chimeric aequorin fused with caveolin-1 reveals a sphingosine kinase 1-regulated Ca²⁺ microdomain in the caveolar compartment.Ilari Pulli et al.Biochimica et biophysica acta, 1853(9), 2173-2182 (2015-04-22) TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.Chien-Hsiung Yu et al.Cell, 183(3), 636-649 (2020-10-09) Delivery of CSF-1R to the lumen of macropinosomes promotes its destruction in macrophages.Jieqiong Lou et al.Journal of cell science, 127(Pt 24), 5228-5239 (2014-10-23) Sulforaphane prevents doxorubicin-induced oxidative stress and cell death in rat H9c2 cells.Bo Li et al.International journal of molecular medicine, 36(1), 53-64 (2015-05-06) ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2α Axis.Eduardo Balsa et al.Molecular cell, 74(5), 877-890 (2019-04-27) Biosynthesized Multivalent Lacritin Peptides Stimulate Exosome Production in Human Corneal Epithelium.Changrim Lee et al.International journal of molecular sciences, 21(17) (2020-08-30) Stage-dependent expression and up-regulation of trypanothione synthetase in amphotericin B resistant Leishmania donovani.Asif Equbal et al.PloS one, 9(6), e97600-e97600 (2014-06-06) Nanoparticles of alkylglyceryl-dextran-graft-poly(lactic acid) for drug delivery to the brain: Preparation and in vitro investigation.Petr Toman et al.Acta biomaterialia, 23, 250-262 (2015-05-20) A functional link between the co-translational protein translocation pathway and the UPR.Rachel Plumb et al.eLife, 4 (2015-05-21) Identification and characterization of a cell division-regulating kinase AKB1 (associated kinase of Trypanosoma brucei 14-3-3) through proteomics study of the Tb14-3-3 binding proteins.Masahiro Inoue et al.Journal of biochemistry, 158(1), 49-60 (2015-02-15) Vascular Expression of Hemoglobin Alpha in Antarctic Icefish Supports Iron Limitation as Novel Evolutionary Driver.Bruce A Corliss et al.Frontiers in physiology, 10, 1389-1389 (2019-11-30) The contribution of thioredoxin-2 reductase and glutathione peroxidase to H(2)O(2) detoxification of rat brain mitochondria.Alexei P Kudin et al.Biochimica et biophysica acta, 1817(10), 1901-1906 (2012-03-09) PLA2G4A/cPLA2-mediated lysosomal membrane damage leads to inhibition of autophagy and neurodegeneration after brain trauma.Chinmoy Sarkar et al.Autophagy, 16(3), 466-485 (2019-06-27) p180 promotes the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum.Xianying A Cui et al.PLoS biology, 10(5), e1001336-e1001336 (2012-06-09) Visualization of endoplasmic reticulum localized mRNAs in mammalian cells.Xianying A Cui et al.Journal of visualized experiments : JoVE, (70)(70), e50066-e50066 (2012-12-29) p180 promotes the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum.Xianying A Cui et al.PLoS biology, 10(5), e1001336-e1001336 (2012-06-09) Visualization of endoplasmic reticulum localized mRNAs in mammalian cells.Xianying A Cui et al.Journal of visualized experiments : JoVE, (70)(70), e50066-e50066 (2012-12-29) Molecular identification of a SNAP-25-like SNARE protein in Paramecium.Christina Schilde et al.Eukaryotic cell, 7(8), 1387-1402 (2008-06-17) Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo.Robert O'Brien et al.The Journal of biological chemistry, 290(31), 19287-19306 (2015-05-31) A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes.P De Groote et al.Cell death and differentiation, 22(6), 1012-1024 (2014-11-29) CRELD1 modulates homeostasis of the immune system in mice and humans.Lorenzo Bonaguro et al.Nature immunology, 21(12), 1517-1527 (2020-11-11) Redox homeostasis maintained by GPX4 facilitates STING activation.Mutian Jia et al.Nature immunology, 21(7), 727-735 (2020-06-17) Unsaturated but not saturated fatty acids induce transcriptional regulation of CCL2 in pancreatic acini. A potential role in acute pancreatitis.A Mateu et al.Biochimica et biophysica acta, 1852(12), 2671-2677 (2015-09-30) Identification of the Mitochondrial Heme Metabolism Complex.Amy E Medlock et al.PloS one, 10(8), e0135896-e0135896 (2015-08-20) CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation.Y Liu et al.Cell death and differentiation, 22(6), 1035-1046 (2014-12-06) Intracellular free calcium mediates glioma cell detachment and cytotoxicity after photodynamic therapy.Xin Hong et al.Lasers in medical science, 24(5), 777-786 (2009-02-10) Strain-specific antiviral activity of iminosugars against human influenza A viruses.S Hussain et al.The Journal of antimicrobial chemotherapy, 70(1), 136-152 (2014-09-17) Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication.Adrian Flierl et al.PloS one, 9(11), e112413-e112413 (2014-11-13) Extraction of cellulose-synthesizing activity of Gluconacetobacter xylinus by alkylmaltoside.Akira Hashimoto et al.Carbohydrate research, 346(17), 2760-2768 (2011-11-11) IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.Jose L Izquierdo-Garcia et al.Cancer research, 75(15), 2999-3009 (2015-06-06) Novel MTND1 mutations cause isolated exercise intolerance, complex I deficiency and increased assembly factor expression.Grainne S Gorman et al.Clinical science (London, England : 1979), 128(12), 895-904 (2015-01-30) Granzyme H is a novel protease expressed by human mast cells.Elin Rönnberg et al.International archives of allergy and immunology, 165(1), 68-74 (2014-10-25) Distinctive roles of unsaturated and saturated fatty acids in hyperlipidemic pancreatitis.Yu-Ting Chang et al.World journal of gastroenterology, 21(32), 9534-9543 (2015-09-04) The FGF-2-triggered protection of cardiac subsarcolemmal mitochondria from calcium overload is mitochondrial connexin 43-dependent.Wattamon Srisakuldee et al.Cardiovascular research, 103(1), 72-80 (2014-03-22) WDHD1 modulates the post-transcriptional step of the centromeric silencing pathway.Chia-Ling Hsieh et al.Nucleic acids research, 39(10), 4048-4062 (2011-01-27) Constitutively active ErbB2 regulates cisplatin-induced cell death in breast cancer cells via pro- and antiapoptotic mechanisms.Haraldur H Sigurðsson et al.Molecular cancer research : MCR, 13(1), 63-77 (2014-08-22) A time-lapse imaging assay to study nuclear envelope breakdown.Sunita S Shankaran et al.Methods in molecular biology (Clifton, N.J.), 931, 111-122 (2012-10-03) Quantification of CatSper1 expression in human spermatozoa and relation to functional parameters.L Tamburrino et al.Human reproduction (Oxford, England), 30(7), 1532-1544 (2015-05-20) The N terminus of the influenza B virus nucleoprotein is essential for virus viability, nuclear localization, and optimal transcription and replication of the viral genome.Lee Sherry et al.Journal of virology, 88(21), 12326-12338 (2014-08-15) In vitro toxicity testing with microplate cell cultures: Impact of cell binding.Michael Gülden et al.Toxicology, 332, 41-51 (2013-12-03) Spiromastixones Inhibit Foam Cell Formation via Regulation of Cholesterol Efflux and Uptake in RAW264.7 Macrophages.Chongming Wu et al.Marine drugs, 13(10), 6352-6365 (2015-10-17) Bak apoptotic pores involve a flexible C-terminal region and juxtaposition of the C-terminal transmembrane domains.S Iyer et al.Cell death and differentiation, 22(10), 1665-1675 (2015-03-07) A trimeric supercomplex of the oxygen-tolerant membrane-bound [NiFe]-hydrogenase from Ralstonia eutropha H16.Stefan Frielingsdorf et al.Biochemistry, 50(50), 10836-10843 (2011-11-22) Mitochondrial EF4 links respiratory dysfunction and cytoplasmic translation in Caenorhabditis elegans.Fang Yang et al.Biochimica et biophysica acta, 1837(10), 1674-1683 (2014-05-20) Ataxia-Telangiectasia Mutated is located in cardiac mitochondria and impacts oxidative phosphorylation.Marguerite Blignaut et al.Scientific reports, 9(1), 4782-4782 (2019-03-20) Mitochondrial dysfunction in some triple-negative breast cancer cell lines: role of mTOR pathway and therapeutic potential.Hélène Pelicano et al.Breast cancer research : BCR, 16(5), 434-434 (2014-09-12) Structure and mechanism of the mitochondrial Ca2+ uniporter holocomplex.Minrui Fan et al.Nature, 582(7810), 129-133 (2020-06-05) The Golgi apparatus regulates cGMP-dependent protein kinase I compartmentation and proteolysis.Shin Kato et al.American journal of physiology. Cell physiology, 308(11), C944-C958 (2015-04-10) Amygdala inhibitory neurons as loci for translation in emotional memories.Prerana Shrestha et al.Nature, 586(7829), 407-411 (2020-10-09) Human Chorionic Gonadotropin Protects Vascular Endothelial Cells from Oxidative Stress by Apoptosis Inhibition, Cell Survival Signalling Activation and Mitochondrial Function Protection.Daniela Surico et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 36(6), 2108-2120 (2015-08-19) Mechanistic analysis of ghrelin-O-acyltransferase using substrate analogs.Martin S Taylor et al.Bioorganic chemistry, 62, 64-73 (2015-08-08) Idebenone-induced recovery of glycerol-3-phosphate and succinate oxidation inhibited by digitonin.H Rauchová et al.Physiological research, 61(3), 259-265 (2012-04-07) Protection of differentiated neuronal NG108-15 cells from P2X7 receptor-mediated toxicity by taurine.Chia-Chia Chao et al.Pharmacological reports : PR, 66(4), 576-584 (2014-06-21) Proteomic Profiling of Mammalian COPII and COPI Vesicles.Frank Adolf et al.Cell reports, 26(1), 250-265 (2019-01-04) Mitochondrial dysfunction related to cell damage induced by 3-hydroxykynurenine and 3-hydroxyanthranilic acid: Non-dependent-effect of early reactive oxygen species production.J Reyes-Ocampo et al.Neurotoxicology, 50, 81-91 (2015-08-10) Controlled Endolysosomal Release of Agents by pH-responsive Polymer Blend Particles.Xi Zhan et al.Pharmaceutical research, 32(7), 2280-2291 (2015-01-17) The first exon duplication mouse model of Duchenne muscular dystrophy: A tool for therapeutic development.Adeline Vulin et al.Neuromuscular disorders : NMD, 25(11), 827-834 (2015-09-15) HIV-1 entry in SupT1-R5, CEM-ss, and primary CD4+ T cells occurs at the plasma membrane and does not require endocytosis.Nikolas Herold et al.Journal of virology, 88(24), 13956-13970 (2014-09-26) The role of miR-125b-mitochondria-caspase-3 pathway in doxorubicin resistance and therapy in human breast cancer.Xiaohong Xie et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 36(9), 7185-7194 (2015-04-22) Synergism of three-drug combinations of sanguinarine and other plant secondary metabolites with digitonin and doxorubicin in multi-drug resistant cancer cells.Safaa Yehia Eid et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(14), 1288-1297 (2012-11-14) A Non-enveloped Virus Hijacks Host Disaggregation Machinery to Translocate across the Endoplasmic Reticulum Membrane.Madhu Sudhan Ravindran et al.PLoS pathogens, 11(8), e1005086-e1005086 (2015-08-06) Quality control in eukaryotic membrane protein overproduction.Jennifer A Thomas et al.Journal of molecular biology, 426(24), 4139-4154 (2014-12-03) A Novel Small-Molecule Inhibitor Targeting CREB-CBP Complex Possesses Anti-Cancer Effects along with Cell Cycle Regulation, Autophagy Suppression and Endoplasmic Reticulum Stress.Jong Woo Lee et al.PloS one, 10(4), e0122628-e0122628 (2015-04-22) The rigid steroid 21-hydroxy-6,19-epoxyprogesterone (21OH-6,19OP) is a dissociated glucocorticoid receptor modulator potentially useful as a novel coadjuvant in breast cancer chemotherapy.Andres J Orqueda et al.Biochemical pharmacology, 89(4), 526-535 (2014-04-17) Targeting cell surface TLR7 for therapeutic intervention in autoimmune diseases.Atsuo Kanno et al.Nature communications, 6, 6119-6119 (2015-02-05) The Mammalian Cell Cycle Regulates Parvovirus Nuclear Capsid Assembly.Jon Gil-Ranedo et al.PLoS pathogens, 11(6), e1004920-e1004920 (2015-06-13) Hydrophobic Interactions Are Key To Drive the Association of Tapasin with Peptide Transporter Subunit TAP2.Elke Rufer et al.Journal of immunology (Baltimore, Md. : 1950), 195(11), 5482-5494 (2015-11-01) Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK.Mengqi Li et al.Cell metabolism, 30(3), 508-524 (2019-06-18) The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 translocon.Karina von der Malsburg et al.Molecular biology of the cell, 26(12), 2168-2180 (2015-04-17) Correlation of disease activity in proliferative glomerulonephritis with glomerular spleen tyrosine kinase expression.Stephen P McAdoo et al.Kidney international, 88(1), 52-60 (2015-02-26) Synthesis of carbamide derivatives bearing tetrahydroisoquinoline moieties and biological evaluation as analgesia drugs in mice.Qianqian Qiu et al.Archiv der Pharmazie, 348(5), 347-352 (2015-04-01) Fatty acid synthase inhibition engages a novel caspase-2 regulatory mechanism to induce ovarian cancer cell death.C-S Yang et al.Oncogene, 34(25), 3264-3272 (2014-08-26) Generation of Ugt1-deficient murine liver cell lines using TALEN technology.Fabiola Porro et al.PloS one, 9(8), e104816-e104816 (2014-08-15) Discovery of Isoplumbagin as a Novel NQO1 Substrate and Anti-Cancer Quinone.Yen-Chi Tsao et al.International journal of molecular sciences, 21(12) (2020-06-25) Forcible destruction of severely misfolded mammalian glycoproteins by the non-glycoprotein ERAD pathway.Satoshi Ninagawa et al.The Journal of cell biology, 211(4), 775-784 (2015-11-18) Identification and Characterization of CD300H, a New Member of the Human CD300 Immunoreceptor Family.Kouta Niizuma et al.The Journal of biological chemistry, 290(36), 22298-22308 (2015-07-30) The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 translocon.Karina von der Malsburg et al.Molecular biology of the cell, 26(12), 2168-2180 (2015-04-17) Ginkgolide B revamps neuroprotective role of apurinic/apyrimidinic endonuclease 1 and mitochondrial oxidative phosphorylation against Aβ25-35 -induced neurotoxicity in human neuroblastoma cells.Navrattan Kaur et al.Journal of neuroscience research, 93(6), 938-947 (2015-02-14) Digitonin synergistically enhances the cytotoxicity of plant secondary metabolites in cancer cells.Safaa Yehia Eid et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(14), 1307-1314 (2012-10-16) Mitochondria-targeted antioxidant preserves contractile properties and mitochondrial function of skeletal muscle in aged rats.Sabzali Javadov et al.Oncotarget, 6(37), 39469-39481 (2015-09-29) Antioxidant effect of 0.2% xanthan gum in ocular surface corneal epithelial cells.Carla Amico et al.Current eye research, 40(1), 72-76 (2014-05-17) Discovery of Isoplumbagin as a Novel NQO1 Substrate and Anti-Cancer Quinone.Yen-Chi Tsao et al.International journal of molecular sciences, 21(12) (2020-06-25) Death Receptor-Induced Apoptosis Signalling Regulation by Ezrin Is Cell Type Dependent and Occurs in a DISC-Independent Manner in Colon Cancer Cells.Elisabetta Iessi et al.PloS one, 10(5), e0126526-e0126526 (2015-05-27) Hydrophobic handoff for direct delivery of peroxisome tail-anchored proteins.Yinxiao Chen et al.Nature communications, 5, 5790-5790 (2014-12-18) Forcible destruction of severely misfolded mammalian glycoproteins by the non-glycoprotein ERAD pathway.Satoshi Ninagawa et al.The Journal of cell biology, 211(4), 775-784 (2015-11-18) Human Chorionic Gonadotropin Protects Vascular Endothelial Cells from Oxidative Stress by Apoptosis Inhibition, Cell Survival Signalling Activation and Mitochondrial Function Protection.Daniela Surico et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 36(6), 2108-2120 (2015-08-19) Mechanistic analysis of ghrelin-O-acyltransferase using substrate analogs.Martin S Taylor et al.Bioorganic chemistry, 62, 64-73 (2015-08-08) Mitochondrial dysfunction related to cell damage induced by 3-hydroxykynurenine and 3-hydroxyanthranilic acid: Non-dependent-effect of early reactive oxygen species production.J Reyes-Ocampo et al.Neurotoxicology, 50, 81-91 (2015-08-10) The first exon duplication mouse model of Duchenne muscular dystrophy: A tool for therapeutic development.Adeline Vulin et al.Neuromuscular disorders : NMD, 25(11), 827-834 (2015-09-15) Proteomic Profiling of Mammalian COPII and COPI Vesicles.Frank Adolf et al.Cell reports, 26(1), 250-265 (2019-01-04) The rigid steroid 21-hydroxy-6,19-epoxyprogesterone (21OH-6,19OP) is a dissociated glucocorticoid receptor modulator potentially useful as a novel coadjuvant in breast cancer chemotherapy.Andres J Orqueda et al.Biochemical pharmacology, 89(4), 526-535 (2014-04-17) Targeting cell surface TLR7 for therapeutic intervention in autoimmune diseases.Atsuo Kanno et al.Nature communications, 6, 6119-6119 (2015-02-05) The Mammalian Cell Cycle Regulates Parvovirus Nuclear Capsid Assembly.Jon Gil-Ranedo et al.PLoS pathogens, 11(6), e1004920-e1004920 (2015-06-13) Controlled Endolysosomal Release of Agents by pH-responsive Polymer Blend Particles.Xi Zhan et al.Pharmaceutical research, 32(7), 2280-2291 (2015-01-17) HIV-1 entry in SupT1-R5, CEM-ss, and primary CD4+ T cells occurs at the plasma membrane and does not require endocytosis.Nikolas Herold et al.Journal of virology, 88(24), 13956-13970 (2014-09-26) The role of miR-125b-mitochondria-caspase-3 pathway in doxorubicin resistance and therapy in human breast cancer.Xiaohong Xie et al.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 36(9), 7185-7194 (2015-04-22) Synergism of three-drug combinations of sanguinarine and other plant secondary metabolites with digitonin and doxorubicin in multi-drug resistant cancer cells.Safaa Yehia Eid et al.Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(14), 1288-1297 (2012-11-14) Promotion of Endoplasmic Reticulum-Associated Degradation of Procathepsin D by Human Herpesvirus 8-Encoded Viral Interleukin-6.Daming Chen et al.Journal of virology, 89(15), 7979-7990 (2015-05-29) Homodimeric anoctamin-1, but not homodimeric anoctamin-6, is activated by calcium increases mediated by the P2Y1 and P2X7 receptors.Michaela Stolz et al.Pflugers Archiv : European journal of physiology, 467(10), 2121-2140 (2015-01-17) CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability.Takeshi Inoue et al.The Journal of experimental medicine, 212(9), 1465-1479 (2015-08-05) An inherited mutation in NLRC4 causes autoinflammation in human and mice.Akiko Kitamura et al.The Journal of experimental medicine, 211(12), 2385-2396 (2014-11-12) Toll-like receptor 4 and MAIR-II/CLM-4/LMIR2 immunoreceptor regulate VLA-4-mediated inflammatory monocyte migration.Naoya Totsuka et al.Nature communications, 5, 4710-4710 (2014-08-20) A mild purification method for polysaccharide binding membrane proteins: phase separation of digitonin extracts to isolate the hyaluronate synthase from Streptococcus sp. in active form.S Prehm et al.Protein expression and purification, 7(4), 343-346 (1996-06-01) Protection of differentiated neuronal NG108-15 cells from P2X7 receptor-mediated toxicity by taurine.Chia-Chia Chao et al.Pharmacological reports : PR, 66(4), 576-584 (2014-06-21) Idebenone-induced recovery of glycerol-3-phosphate and succinate oxidation inhibited by digitonin.H Rauchová et al.Physiological research, 61(3), 259-265 (2012-04-07) Structure and mechanism of the mitochondrial Ca2+ uniporter holocomplex.Minrui Fan et al.Nature, 582(7810), 129-133 (2020-06-05) The Golgi apparatus regulates cGMP-dependent protein kinase I compartmentation and proteolysis.Shin Kato et al.American journal of physiology. Cell physiology, 308(11), C944-C958 (2015-04-10) Amygdala inhibitory neurons as loci for translation in emotional memories.Prerana Shrestha et al.Nature, 586(7829), 407-411 (2020-10-09) Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.Binghua Li et al.EBioMedicine, 39, 239-254 (2018-12-18) Quinone-induced protein handling changes: implications for major protein handling systems in quinone-mediated toxicity.Rui Xiong et al.Toxicology and applied pharmacology, 280(2), 285-295 (2014-08-26) Piperine inhibits the growth and motility of triple-negative breast cancer cells.Anna L Greenshields et al.Cancer letters, 357(1), 129-140 (2014-12-03) Daclatasvir inhibits hepatitis C virus NS5A motility and hyper-accumulation of phosphoinositides.Vineela Chukkapalli et al.Virology, 476, 168-179 (2014-12-30) The lipopeptide toxins anabaenolysin A and B target biological membranes in a cholesterol-dependent manner.Linn Oftedal et al.Biochimica et biophysica acta, 1818(12), 3000-3009 (2012-07-31) Comparative analysis of seven viral nuclear export signals (NESs) reveals the crucial role of nuclear export mediated by the third NES consensus sequence of nucleoprotein (NP) in influenza A virus replication.Nopporn Chutiwitoonchai et al.PloS one, 9(8), e105081-e105081 (2014-08-15) Crosslinking constraints and computational models as complementary tools in modeling the extracellular domain of the glycine receptor.Zhenyu Liu et al.PloS one, 9(7), e102571-e102571 (2014-07-16) A Non-enveloped Virus Hijacks Host Disaggregation Machinery to Translocate across the Endoplasmic Reticulum Membrane.Madhu Sudhan Ravindran et al.PLoS pathogens, 11(8), e1005086-e1005086 (2015-08-06) Quality control in eukaryotic membrane protein overproduction.Jennifer A Thomas et al.Journal of molecular biology, 426(24), 4139-4154 (2014-12-03) Human COX20 cooperates with SCO1 and SCO2 to mature COX2 and promote the assembly of cytochrome c oxidase.Myriam Bourens et al.Human molecular genetics, 23(11), 2901-2913 (2014-01-10) Evaluation of the mitochondrial respiratory chain and oxidative phosphorylation system using blue native gel electrophoresis.Francisca Díaz et al.Current protocols in human genetics, Chapter 19, Unit19-Unit19 (2009-10-07) Co-abrogation of Chk1 and Chk2 by potent oncolytic adenovirus potentiates the antitumor efficacy of cisplatin or irradiation.F Ye et al.Cancer gene therapy, 21(5), 209-217 (2014-05-24) GFAP phosphorylation studied in digitonin-permeabilized astrocytes: standardization of conditions.J Karl et al.Brain research, 853(1), 32-40 (2000-01-08) Inhibition of an NAD⁺ salvage pathway provides efficient and selective toxicity to human pluripotent stem cells.Erin M Kropp et al.Stem cells translational medicine, 4(5), 483-493 (2015-04-03) Insulin Modulates the Na+/Mg2+ Exchanger SLC41A1 and Influences Mg2+ Efflux from Intracellular Stores in Transgenic HEK293 Cells.Lucia Mastrototaro et al.The Journal of nutrition, 145(11), 2440-2447 (2015-09-12) Sorafenib-induced defective autophagy promotes cell death by necroptosis.Pedram Kharaziha et al.Oncotarget, 6(35), 37066-37082 (2015-09-30) Safranine as a fluorescent probe for the evaluation of mitochondrial membrane potential in isolated organelles and permeabilized cells.Tiago R Figueira et al.Methods in molecular biology (Clifton, N.J.), 810, 103-117 (2011-11-08) A metabolic phenotype based on mitochondrial ribosomal protein expression as a predictor of lymph node metastasis in papillary thyroid carcinoma.Jandee Lee et al.Medicine, 94(2), e380-e380 (2015-01-16) Intrinsically Disordered Protein TEX264 Mediates ER-phagy.Haruka Chino et al.Molecular cell, 74(5), 909-921 (2019-04-23) In vitro evaluation of novel N-acetylalaninate prodrugs that selectively induce apoptosis in prostate cancer cells.Christopher A McGoldrick et al.BMC cancer, 14, 675-675 (2014-09-23) Ku70 is essential for histone deacetylase inhibitor trichostatin A-induced apoptosis.Jin Meng et al.Molecular medicine reports, 12(1), 581-586 (2015-02-20) Signal peptide peptidase functions in ERAD to cleave the unfolded protein response regulator XBP1u.Chia-yi Chen et al.The EMBO journal, 33(21), 2492-2506 (2014-09-23) The Leishmania donovani histidine acid ecto-phosphatase LdMAcP: insight into its structure and function.Amalia Papadaki et al.The Biochemical journal, 467(3), 473-486 (2015-02-20) Neuroprotective effect of diphenyl diselenide in a experimental stroke model: maintenance of redox system in mitochondria of brain regions.Fernando Dobrachinski et al.Neurotoxicity research, 26(4), 317-330 (2014-03-13) Phosphorylated ubiquitin chain is the genuine Parkin receptor.Kei Okatsu et al.The Journal of cell biology, 209(1), 111-128 (2015-04-08) Identification of SHIP-1 and SHIP-2 homologs in channel catfish, Ictalurus punctatus.Erin B Taylor et al.Developmental and comparative immunology, 51(1), 79-87 (2015-03-07) [Effects of sodium nitroprusside and nitrite on ouabaine-sensitive Na+, K(+)-ATPase activity of myometrium smooth muscle].Iu V Danylovich et al.Ukrains'kyi biokhimichnyi zhurnal (1999 ), 82(6), 33-41 (2011-08-03) Hemin inhibits the large conductance potassium channel in brain mitochondria: a putative novel mechanism of neurodegeneration.Bartłomiej Augustynek et al.Experimental neurology, 257, 70-75 (2014-05-06) Respiration characteristics of mitochondria in parental and giant transformed cells of the murine Nemeth-Kellner lymphoma.Rostyslav O Horbay et al.Cell biology international, 36(1), 71-77 (2011-09-09) A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells.Hee Chan Yoo et al.Cell metabolism, 31(2), 267-283 (2019-12-24) Ectromelia virus encodes an anti-apoptotic protein that regulates cell death.Ninad Mehta et al.Virology, 475, 74-87 (2014-12-03) Infectious Bursal Disease Virus non-structural protein VP5 is not a transmembrane protein.Juan Manuel Carballeda et al.Virology, 483, 312-317 (2015-06-06) Mutations in the cholesterol transporter gene ABCA5 are associated with excessive hair overgrowth.Gina M DeStefano et al.PLoS genetics, 10(5), e1004333-e1004333 (2014-05-17) The use of digitonin-permeabilized mammalian cells for measuring enzyme activities in the course of studies on lipid metabolism.Math J H Geelen Analytical biochemistry, 347(1), 1-9 (2005-11-18) Targeting of splice variants of human cytochrome P450 2C8 (CYP2C8) to mitochondria and their role in arachidonic acid metabolism and respiratory dysfunction.Prachi Bajpai et al.The Journal of biological chemistry, 289(43), 29614-29630 (2014-08-28) In vitro engineering of human 3D chondrosarcoma: a preclinical model relevant for investigations of radiation quality impact.Dounia Houria Hamdi et al.BMC cancer, 15, 579-579 (2015-08-09) Plasma membrane profiling defines an expanded class of cell surface proteins selectively targeted for degradation by HCMV US2 in cooperation with UL141.Jye-Lin Hsu et al.PLoS pathogens, 11(4), e1004811-e1004811 (2015-04-16) NLRP7, Involved in Hydatidiform Molar Pregnancy (HYDM1), Interacts with the Transcriptional Repressor ZBTB16.Heike Singer et al.PloS one, 10(6), e0130416-e0130416 (2015-06-30) The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase.Marc M Schumacher et al.eLife, 4 (2015-03-06) Ca(2+)-dependent permeabilization of mitochondria and liposomes by palmitic and oleic acids: a comparative study.Konstantin N Belosludtsev et al.Biochimica et biophysica acta, 1838(10), 2600-2606 (2014-07-06) A Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T α-Synuclein Toxicity.Rui Xiong et al.Molecular pharmacology, 88(6), 1045-1054 (2015-09-26) Assembly of the rotor component of yeast mitochondrial ATP synthase is enhanced when Atp9p is supplied by Atp9p-Cox6p complexes.Chen-Hsien Su et al.The Journal of biological chemistry, 289(45), 31605-31616 (2014-09-26) A lipid switch unlocks Parkinson's disease-associated ATP13A2.Tine Holemans et al.Proceedings of the National Academy of Sciences of the United States of America, 112(29), 9040-9045 (2015-07-03) Analysis of mutant SOD1 electrophoretic mobility by Blue Native gel electrophoresis; evidence for soluble multimeric assemblies.Hilda H Brown et al.PloS one, 9(8), e104583-e104583 (2014-08-15) Prevalence, genotype and antimicrobial resistance of Clostridium difficile isolates from healthy pets in Eastern China.Yanxia Wei et al.BMC infectious diseases, 19(1), 46-46 (2019-01-13) Characterization of manganese superoxide dismutase from a marine cyanobacterium Leptolyngbya valderiana BDU20041.Balakrishnan Priya et al.Saline systems, 6, 6-6 (2010-06-08)
备注

Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.

Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).

名称 CAS号

相关产品

相关资讯

热门标签
询 单
请 填 写 相 关 信 息
产品信息
产品名称
别名
CAS号
结构式 上传
联系方式
公司
联系人
电话
邮箱
内容
提交