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Lymphocyte-suppressing effects of omega-3 fatty acids in bezafibrate-treated patients with isolated hypertriglyceridemia.Robert Krysiak et al.European journal of internal medicine, 23(6), e166-e167 (2012-08-07) Hemostatic effects of omega-3 fatty acids in isolated hypertriglyceridemic patients treated with bezafibrate.Robert Krysiak et al.European journal of internal medicine, 23(6), e168-e169 (2012-08-07) Update on the use of fibrates: focus on bezafibrate.Ilan Goldenberg et al.Vascular health and risk management, 4(1), 131-141 (2008-07-17) Bezafibrate, a lipid-lowering pharmaceutical, as a potential endocrine disruptor in male zebrafish (Danio rerio)Velasco-Santamaria YM, et al. Aquatic Toxicology (Amsterdam, Netherlands), 105(1-2), 107-118 (2011) Determination of pharmaceuticals in bivalves using QuEChERS extraction and liquid chromatography-tandem mass spectrometry.Mireia Núñez et al.Analytical and bioanalytical chemistry, 407(13), 3841-3849 (2015-03-18) Anticholestatic effects of bezafibrate in patients with primary biliary cirrhosis treated with ursodeoxycholic acid.Akira Honda et al.Hepatology (Baltimore, Md.), 57(5), 1931-1941 (2012-08-23) Bezafibrate induced rhabdomyolysis.E Kanterewicz et al.Annals of the rheumatic diseases, 51(4), 536-538 (1992-04-01) Sjögren-Larsson syndrome in clinical practice.Joris Fuijkschot et al.Journal of inherited metabolic disease, 35(6), 955-962 (2012-07-27) Long-term bezafibrate treatment improves skin and spleen phenotypes of the mtDNA mutator mouse.Lloye M Dillon et al.PloS one, 7(9), e44335-e44335 (2012-09-11) Enzyme enhancers for the treatment of Fabry and Pompe disease.Jan Lukas et al.Molecular therapy : the journal of the American Society of Gene Therapy, 23(3), 456-464 (2014-11-21) Synthesis and biological evaluation of ester prodrugs of Benzafibrate as orally active hypolipidemic agents.Babasaheb P Bandgar et al.European journal of medicinal chemistry, 57, 217-224 (2012-10-13) [BECAIT [Bezafibrate Coronary Atherosclerosis Intervention Trial]].G Yoshino et al.Nihon rinsho. Japanese journal of clinical medicine, 59 Suppl 3, 433-435 (2001-05-12) Determination of selected pharmaceuticals in tap water and drinking water treatment plant by high-performance liquid chromatography-triple quadrupole mass spectrometer in Beijing, China.Mei-Quan Cai et al.Environmental science and pollution research international, 22(3), 1854-1867 (2014-09-10) Drug Redeployment to Kill Leukemia and Lymphoma Cells by Disrupting SCD1-Mediated Synthesis of Monounsaturated Fatty Acids.Andrew D Southam et al.Cancer research, 75(12), 2530-2540 (2015-05-07) Pharmaceutically active compounds in sludge stabilization treatments: anaerobic and aerobic digestion, wastewater stabilization ponds and composting.Julia Martín et al.The Science of the total environment, 503-504, 97-104 (2014-06-10) Simvastatin but not bezafibrate decreases plasma lipoprotein-associated phospholipase A₂ mass in type 2 diabetes mellitus: relevance of high sensitive C-reactive protein, lipoprotein profile and low-density lipoprotein (LDL) electronegativity.Alexander Constantinides et al.European journal of internal medicine, 23(7), 633-638 (2012-08-21) Hyperthyroidism causes cardiac dysfunction by mitochondrial impairment and energy depletion.Sangeeta Maity et al.The Journal of endocrinology, 217(2), 215-228 (2013-02-23) Uptake and effects of a mixture of widely used therapeutic drugs in Eruca sativa L. and Zea mays L. plants.Milena Marsoni et al.Ecotoxicology and environmental safety, 108, 52-57 (2014-07-22) Functional analysis of iPSC-derived myocytes from a patient with carnitine palmitoyltransferase II deficiency.Tetsuhiko Yasuno et al.Biochemical and biophysical research communications, 448(2), 175-181 (2014-05-02) Bezafibrate. An update of its pharmacology and use in the management of dyslipidaemia.K L Goa et al.Drugs, 52(5), 725-753 (1996-11-01) Effects of bezafibrate on hepatic cholesterol metabolism.D Ståhlberg et al.European journal of clinical pharmacology, 40 Suppl 1, S33-S36 (1991-01-01) Bezafibrate derivatives as potent effectors of hemoglobin.C Poyart et al.Methods in enzymology, 232, 496-513 (1994-01-01) Environmental friendly method for urban wastewater monitoring of micropollutants defined in the Directive 2013/39/EU and Decision 2015/495/EU.Ana R Ribeiro et al.Journal of chromatography. A, 1418, 140-149 (2015-10-04) Treatment of selected pharmaceuticals by ferrate(VI): performance, kinetic studies and identification of oxidation products.Zhengwei Zhou et al.Journal of pharmaceutical and biomedical analysis, 106, 37-45 (2014-07-27) Bezafibrate can be a new treatment option for mitochondrial fatty acid oxidation disorders: evaluation by in vitro probe acylcarnitine assay.Seiji Yamaguchi et al.Molecular genetics and metabolism, 107(1-2), 87-91 (2012-07-31) How peroxisomes affect aflatoxin biosynthesis in Aspergillus flavus.Massimo Reverberi et al.PloS one, 7(10), e48097-e48097 (2012-10-25) Bezafibrate administration improves behavioral deficits and tau pathology in P301S mice.Magali Dumont et al.Human molecular genetics, 21(23), 5091-5105 (2012-08-28) Group X secreted phospholipase A(2) induces lipid droplet formation and prolongs breast cancer cell survival.Anja Pucer et al.Molecular cancer, 12(1), 111-111 (2013-09-28) Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-induced diabetic miceFranko A, et al. Diabetes, 65(9), 2540-2552 (2016) PPAR agonists regulate brain gene expression: relationship to their effects on ethanol consumption.Laura B Ferguson et al.Neuropharmacology, 86, 397-407 (2014-07-19) Hepatocyte nuclear factor 4α and downstream secreted phospholipase A2 GXIIB regulate production of infectious hepatitis C virus.Xinlei Li et al.Journal of virology, 88(1), 612-627 (2013-11-01) Novel Mechanism of Cholesterol Transport by ABCA5 in Macrophages and Its Role in Dyslipidemia.Aleepta Guha Ray et al.Journal of molecular biology, 432(17), 4922-4941 (2020-07-21) Removal of naproxen and bezafibrate by activated sludge under aerobic conditions: kinetics and effect of substrates.Ying Tang et al.Biotechnology and applied biochemistry, 61(3), 333-341 (2013-10-18) BFCOD activity in fish cell lines and zebrafish embryos and its modulation by chemical ligands of human aryl hydrocarbon and nuclear receptors.N Creusot et al.Environmental science and pollution research international, 22(21), 16393-16404 (2014-12-05) Square-wave voltammetric determination of bezafibrate in pharmaceutical formulations using a cathodically pretreated boron-doped diamond electrode.Jorge Armando Ardila et al.Talanta, 103, 201-206 (2012-12-04) Bezafibrate for primary biliary cirrhosis.Jelena S Rudic et al.The Cochrane database of systematic reviews, 1, CD009145-CD009145 (2012-01-20) Fibrates as adjuvant therapy for chronic cholestatic liver disease: its time has come.Nisanne S Ghonem et al.Hepatology (Baltimore, Md.), 57(5), 1691-1693 (2012-11-24) [Management of PBC cases failing to respond to UDCA].Atsushi Tanaka Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 110(1), 16-21 (2013-01-11) Mechanism and stability of an Fe-based 2D MOF during the photoelectro-Fenton treatment of organic micropollutants under UVA and visible light irradiation.Zhihong Ye et al.Water research, 184, 115986-115986 (2020-07-20) Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons.Alexander Tenenbaum et al.Cardiovascular diabetology, 4, 14-14 (2005-09-20) Secondary preventive potential of lipid-lowering drugs. The Bezafibrate Coronary Atherosclerosis Intervention Trial (BECAIT).U de Faire et al.European heart journal, 17 Suppl F, 37-42 (1996-12-01) Balanced pan-PPAR activator bezafibrate in combination with statin: comprehensive lipids control and diabetes prevention?Alexander Tenenbaum et al.Cardiovascular diabetology, 11, 140-140 (2012-11-16) Effects of antihypertensive and triglyceride-lowering agents on hepatic copper concentrations in rats with fatty liver disease.Zvi Ackerman et al.Basic & clinical pharmacology & toxicology, 115(6), 545-551 (2014-07-01) Simultaneous determination of polar pharmaceuticals and personal care products in biological organs and tissues.Rumi Tanoue et al.Journal of chromatography. A, 1355, 193-205 (2014-06-25) Induction of 1-acylglycerophosphocholine acyltransferase genes by fibrates in the liver of rats.Tohru Yamazaki et al.Biological & pharmaceutical bulletin, 35(9), 1509-1515 (2012-09-15) Synthesis of highly water-soluble fibrate derivatives via BGLation.Hisao Nemoto et al.Bioorganic & medicinal chemistry letters, 22(20), 6425-6428 (2012-09-15) Identification of antihyperlipidemic constituents from the roots of Rubia yunnanensis Diels.Yang Gao et al.Journal of ethnopharmacology, 155(2), 1315-1321 (2014-07-30) Effects of bezafibrate treatment in a patient and a carrier with mutations in the PNPLA2 gene, causing neutral lipid storage disease with myopathy.Tineke van de Weijer et al.Circulation research, 112(5), e51-e54 (2013-03-02) Metabolomics reveal 1-palmitoyl lysophosphatidylcholine production by peroxisome proliferator-activated receptor α.Haruya Takahashi et al.Journal of lipid research, 56(2), 254-265 (2014-12-17) Disorders of lipid metabolism in patients with HIV disease treated with antiretroviral agents: frequency, relationship with administered drugs, and role of hypolipidaemic therapy with bezafibrate.R Manfredi et al.The Journal of infection, 42(3), 181-188 (2001-09-08) High glucose potentiates L-FABP mediated fibrate induction of PPARα in mouse hepatocytes.Anca D Petrescu et al.Biochimica et biophysica acta, 1831(8), 1412-1425 (2013-06-12) Results of the Bezafibrate Coronary Atherosclerosis Intervention Trial (BECAIT) and an update on trials now in progress.C G Ericsson European heart journal, 19 Suppl H, H37-H41 (1998-08-26) Pharmaceuticals in the freshwater invertebrate, Gammarus pulex, determined using pulverised liquid extraction, solid phase extraction and liquid chromatography-tandem mass spectrometry.Thomas H Miller et al.The Science of the total environment, 511, 153-160 (2014-12-30) Inflammation and future risk of symptomatic heart failure in patients with stable coronary artery disease.Alon Eisen et al.American heart journal, 167(5), 707-714 (2014-04-29) Retardation of coronary atherosclerosis: the Bezafibrate Coronary Atherosclerosis Intervention Trial (BECAIT) and other angiographic trials.U de Faire et al.Cardiovascular drugs and therapy, 11 Suppl 1, 257-263 (1997-05-01) Omega-3 fatty acids enhance monocyte-suppressing effect of bezafibrate in patients with isolated hypertriglyceridemia.Robert Krysiak et al.European journal of internal medicine, 23(7), e171-e172 (2012-08-03) Phospholipase D activation mediates cobalamin-induced downregulation of Multidrug Resistance-1 gene and increase in sensitivity to vinblastine in HepG2 cells.Véronique Marguerite et al.The international journal of biochemistry & cell biology, 45(2), 213-220 (2012-10-04) [A case report of acute neuromyopathy induced by concomitant use of colchicine and bezafibrate].Masayuki Sugie et al.No to shinkei = Brain and nerve, 57(9), 785-790 (2005-10-27) Inhibition of NF-κB activation by 4-hydroxynonenal contributes to liver injury in a mouse model of alcoholic liver disease.Xiaobing Dou et al.The American journal of pathology, 181(5), 1702-1710 (2012-09-18) Bezafibrate. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hyperlipidaemia.J P Monk et al.Drugs, 33(6), 539-576 (1987-06-01) Potent and PPARα-independent anti-proliferative action of the hypolipidemic drug fenofibrate in VEGF-dependent angiosarcomas in vitro.Yasser Majeed et al.Scientific reports, 9(1), 6316-6316 (2019-04-21) Statin and fibrate combination does not additionally lower plasma cholesteryl ester transfer in type 2 diabetes mellitus.Rindert de Vries et al.Clinical laboratory, 58(11-12), 1231-1239 (2013-01-08) Rosiglitazone and bezafibrate modulate gene expression in a rat model of non-alcoholic fatty liver disease--a historical prospective.Hemda Schmilovitz-Weiss et al.Lipids in health and disease, 12, 41-41 (2013-03-28) Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo miceFranko A, et al. Molecular Metabolism, 6(3), 256-266 (2017) Bezafibrate for X-linked adrenoleukodystrophy.Marc Engelen et al.PloS one, 7(7), e41013-e41013 (2012-08-23)

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