没有数据	没有数据

没有数据	没有数据

来源	SDS样本
没有数据	没有数据

产品合成路线

更多

名称	CAS号

更多

文章

同行评议文献

Plasma hydroxy-metronidazole/metronidazole ratio can detect early changes in hepatic function in ethanol-induced liver injury.C M Da Silva et al.Alimentary pharmacology & therapeutics, 13(10), 1335-1341 (1999-10-30) Antibacterial activity and pharmacokinetics of nitroimidazoles. A review.T Bergan Scandinavian journal of infectious diseases. Supplementum, 46, 64-71 (1985-01-01) Fate of priority pharmaceuticals and their main metabolites and transformation products in microalgae-based wastewater treatment systems.María Jesús García-Galán et al.Journal of hazardous materials, 390, 121771-121771 (2020-03-05) Optimized liquid-chromatographic determination of metronidazole and its metabolites in plasma.R A Gibson et al.Clinical chemistry, 30(5), 784-787 (1984-05-01) Faecal metronidazole concentrations during oral and intravenous therapy for antibiotic associated colitis due to Clostridium difficile.R P Bolton et al.Gut, 27(10), 1169-1172 (1986-10-01) In vitro activities of metronidazole and its hydroxy metabolite against Bacteroides spp.S L Pendland et al.Antimicrobial agents and chemotherapy, 38(9), 2106-2110 (1994-09-01) Fast and comprehensive multi-residue analysis of a broad range of human and veterinary pharmaceuticals and some of their metabolites in surface and treated waters by ultra-high-performance liquid chromatography coupled to quadrupole-linear ion trap tandem mass spectrometry.Gros M, et al. Journal of Chromatography A, 1248(6), 104-121 (2012) Multiclass screening method to detect more than fifty banned substances in bovine bile and urine.Simone Moretti et al.Analytica chimica acta, 1032, 56-67 (2018-08-26) PHARMACOKINETICS OF A SINGLE DOSE OF METRONIDAZOLE AFTER RECTAL ADMINISTRATION IN CAPTIVE ASIAN ELEPHANTS (ELEPHAS MAXIMUS).Samantha J Sander et al.Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 47(1), 1-5 (2016-03-25) Development of a monoclonal antibody-based indirect competitive enzyme-linked immunosorbent assay for nitroimidazoles in edible animal tissues and feeds.Wei Han et al.Journal of pharmaceutical and biomedical analysis, 120, 84-91 (2015-12-31) Comparative antimicrobial activity of metronidazole and the hydroxy metabolite against Gardnerella vaginalis.E D Ralph Scandinavian journal of infectious diseases. Supplementum, 40, 115-120 (1983-01-01) Assay of metronidazole by HPLC compared with microbial method.B Salvesen et al.Scandinavian journal of gastroenterology. Supplement, 91, 31-43 (1984-01-01) Using In Silico Fragmentation to Improve Routine Residue Screening in Complex Matrices.Anton Kaufmann et al.Journal of the American Society for Mass Spectrometry, 28(12), 2705-2715 (2017-09-14) Pharmacokinetics of metronidazole in patients undergoing continuous ambulatory peritoneal dialysis.D R Guay et al.Antimicrobial agents and chemotherapy, 25(3), 306-310 (1984-03-01) Quantitative multiresidue method for about 100 veterinary drugs in different meat matrices by sub 2-particulate high-performance liquid chromatography coupled to time of flight mass spectrometry.Kaufmann A, et al. Journal of Chromatography A, 1194(1), 66-79 (2008) Pharmacokinetics of metronidazole and its principal metabolites and their activity against Gardnerella vaginalis.C S Easmon et al.The British journal of venereal diseases, 58(4), 246-249 (1982-08-01) Plasma hydroxy-metronidazole/metronidazole ratio in patients with liver disease and in healthy volunteers.M N Muscará et al.British journal of clinical pharmacology, 40(5), 477-480 (1995-11-01) Using In Silico Fragmentation to Improve Routine Residue Screening in Complex Matrices.Anton Kaufmann et al.Journal of the American Society for Mass Spectrometry, 28(12), 2705-2715 (2017-09-14) The effect of omeprazole on the pharmacokinetics of metronidazole and hydroxymetronidazole in human plasma, saliva and gastric juice.M J Jessa et al.British journal of clinical pharmacology, 44(3), 245-253 (1997-09-20) Relative susceptibilities of Gardnerella vaginalis (Haemophilus vaginalis), Neisseria gonorrhoeae, and Bacteroides fragilis to Metronidazole and its two major metabolites.E D Ralph et al.Sexually transmitted diseases, 7(4), 157-160 (1980-10-01) Transfer of nitroimidazoles from contaminated beeswax to honey.Kamila Mitrowska et al.Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 34(4), 573-581 (2016-11-15) Pharmacokinetics of metronidazole and its major metabolite after a high intravenous dose.T Bergan et al.Scandinavian journal of gastroenterology. Supplement, 91, 113-123 (1984-01-01) In vitro activity of azlocillin, metronidazole and its hydroxy metabolite against anaerobes. Bacteriostatic synergism studies.H Werner et al.Arzneimittel-Forschung, 33(4), 574-577 (1983-01-01) Systemic concentrations of metronidazole and its main metabolites after intravenous oral and vaginal administration.B Fredricsson et al.Gynecologic and obstetric investigation, 24(3), 200-207 (1987-01-01) Metronidazole excretion in human milk and its effect on the suckling neonate.C M Passmore et al.British journal of clinical pharmacology, 26(1), 45-51 (1988-07-01) Determination and confirmation of metronidazole, dimetridazole, ronidazole and their metabolites in bovine muscle by LC-MS/MS.Granja MMHR, et al. Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment, 30(6), 970-976 (2013) Rapid and selective high-performance liquid chromatographic method for the determination of metronidazole and its active metabolite in human plasma, saliva and gastric juice.M J Jessa et al.Journal of chromatography. B, Biomedical applications, 677(2), 374-379 (1996-03-03) Application of solid phase microextraction followed by liquid chromatography-mass spectrometry in the determination of antibiotic drugs and their metabolites in human whole blood and tissue samples.Malgorzata Szultka-Mlynska et al.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1086, 153-165 (2018-04-21) Intravenous metronidazole in the newborn.P Hall et al.Archives of disease in childhood, 58(7), 529-531 (1983-07-01) Synergistic effects between amoxicillin, metronidazole, and the hydroxymetabolite of metronidazole against Actinobacillus actinomycetemcomitans.M J Pavicić et al.Antimicrobial agents and chemotherapy, 35(5), 961-966 (1991-05-01) Metronidazole elimination is preserved in the elderly.S Loft et al.Human & experimental toxicology, 9(3), 155-159 (1990-05-01) Activity of metronidazole and its hydroxy metabolite against clinical isolates of Actinobacillus actinomycetemcomitans.H Jousimies-Somer et al.Oral microbiology and immunology, 3(1), 32-34 (1988-03-01) Multiresidue method for the simultaneous determination of veterinary medicinal products, feed additives and illegal dyes in eggs using liquid chromatography-tandem mass spectrometry.Marta Piatkowska et al.Food chemistry, 197(Pt A), 571-580 (2015-12-01) Metronidazole metabolite and Gardnerella vaginalis (Corynebacterium vaginale)M J Baldson et al.Lancet (London, England), 1(8229), 1112-1112 (1981-05-16) Serum concentrations of metronidazole and its main metabolite in patients with active Crohn's disease: correlation with disease activity and therapeutic efficacy?M U Schneider et al.Chemotherapy, 30(6), 345-352 (1984-01-01)

备注