询 单
请 填 写 相 关 信 息
产品信息
产品名称
别名
CAS号
结构式 上传
联系方式
公司
联系人
电话
邮箱
内容
提交
中文版 English
请输入产品名称、CAS式、分子式
2,4-Dichloropyrimidine-5-carbonitrile | CAS:3177-24-0
2,4-Dichloropyrimidine-5-carbonitrile
  • 名称:2,4-二氯嘧啶-5-甲腈 | 2,4-Dichloropyrimidine-5-carbonitrile
  • CAS号:3177-24-0
  • 别名:2,4-Dichloro-5-cyanopyrimidine
  • 分子式:C5HCl2N3
  • 分子量:173.99
  • EINESC号:

产品描述

物理化学性质

熔点 62-63 ºC**
密度 1.60±0.1 g/cm3 (20 ºC

安全数据

没有数据没有数据

SDS

来源 SDS样本
没有数据没有数据
产品合成路线
更多

名称 CAS号
更多
文章
同行评议文献
Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons.Camille Brochier et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(20), 8621-8632 (2013-05-17) Regulation of RNA polymerase II activation by histone acetylation in single living cells.Timothy J Stasevich et al.Nature, 516(7530), 272-275 (2014-09-26) ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.Hong Wen et al.Nature, 508(7495), 263-268 (2014-03-05) New insights into ubiquitin E3 ligase mechanism.Christopher E Berndsen et al.Nature structural & molecular biology, 21(4), 301-307 (2014-04-05) De novo mutations in histone-modifying genes in congenital heart disease.Samir Zaidi et al.Nature, 498(7453), 220-223 (2013-05-15) High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation.Matthew D Simon et al.Nature, 504(7480), 465-469 (2013-10-29) Repression of RNA polymerase I upon stress is caused by inhibition of RNA-dependent deacetylation of PAF53 by SIRT7.Sifan Chen et al.Molecular cell, 52(3), 303-313 (2013-11-12) Structural insights into estrogen receptor α methylation by histone methyltransferase SMYD2, a cellular event implicated in estrogen signaling regulation.Yuanyuan Jiang et al.Journal of molecular biology, 426(20), 3413-3425 (2014-03-07) Nonenzymatic protein acylation as a carbon stress regulated by sirtuin deacylases.Gregory R Wagner et al.Molecular cell, 54(1), 5-16 (2014-04-15) Chemomechanical caries removal in primary molars : evaluation of marginal leakage and shear bond strength in bonded restorations--an in vitro study.P M Viral et al.The Journal of clinical pediatric dentistry, 37(3), 269-274 (2013-07-17) Targeting bromodomains: epigenetic readers of lysine acetylation.Panagis Filippakopoulos et al.Nature reviews. Drug discovery, 13(5), 337-356 (2014-04-23) Effect of charged amino acid side chain length on lateral cross-strand interactions between carboxylate-containing residues and lysine analogues in a β-hairpin.Hsiou-Ting Kuo et al.Biochemistry, 52(51), 9212-9222 (2013-12-18) Regulation of histone acetyltransferase TIP60 function by histone deacetylase 3.Jingjie Yi et al.The Journal of biological chemistry, 289(49), 33878-33886 (2014-10-11) Modulation of hydrophobic interactions by proximally immobilized ions.C Derek Ma et al.Nature, 517(7534), 347-350 (2015-01-17) Developmental enhancers are marked independently of zygotic Nodal signals in Xenopus.Rakhi Gupta et al.Developmental biology, 395(1), 38-49 (2014-09-11) Context dependency of Set1/COMPASS-mediated histone H3 Lys4 trimethylation.Janet L Thornton et al.Genes & development, 28(2), 115-120 (2014-01-10) Prostaglandin receptor EP₁-mediated differential degradation of cyclooxygenases involves a specific lysine residue.Almog Spector-Chotiner et al.Biochemical and biophysical research communications, 443(2), 738-742 (2013-12-18) Acetylation at lysine 346 controls the transforming activity of the HTLV-1 Tax oncoprotein in the Rat-1 fibroblast model.Julie Lodewick et al.Retrovirology, 10, 75-75 (2013-07-25) Hidden complexity of synaptic receptive fields in cat V1.Julien Fournier et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(16), 5515-5528 (2014-04-18) Structural biology-based insights into combinatorial readout and crosstalk among epigenetic marks.Jiamu Du et al.Biochimica et biophysica acta, 1839(8), 719-727 (2014-04-22) Understanding the relationship between DNA methylation and histone lysine methylation.Nathan R Rose et al.Biochimica et biophysica acta, 1839(12), 1362-1372 (2014-02-25) Decoding the histone code: Role of H3K36me3 in mismatch repair and implications for cancer susceptibility and therapy.Guo-Min Li Cancer research, 73(21), 6379-6383 (2013-10-23) SUMOylation regulates telomere length by targeting the shelterin subunit Tpz1(Tpp1) to modulate shelterin-Stn1 interaction in fission yeast.Keisuke Miyagawa et al.Proceedings of the National Academy of Sciences of the United States of America, 111(16), 5950-5955 (2014-04-09) Trimethylation of histone H3 lysine 36 by human methyltransferase PRDM9 protein.Mohammad S Eram et al.The Journal of biological chemistry, 289(17), 12177-12188 (2014-03-19) Bromodomain and extraterminal (BET) protein inhibition suppresses human T cell leukemia virus 1 (HTLV-1) Tax protein-mediated tumorigenesis by inhibiting nuclear factor κB (NF-κB) signaling.Xuewei Wu et al.The Journal of biological chemistry, 288(50), 36094-36105 (2013-11-06) Pyrrolysyl-tRNA synthetase: an ordinary enzyme but an outstanding genetic code expansion tool.Wei Wan et al.Biochimica et biophysica acta, 1844(6), 1059-1070 (2014-03-19) Hyperactivation of the human plasma membrane Ca2+ pump PMCA h4xb by mutation of Glu99 to Lys.Luciana R Mazzitelli et al.The Journal of biological chemistry, 289(15), 10761-10768 (2014-03-04) Diversity-oriented synthesis of azapeptides with basic amino acid residues: aza-lysine, aza-ornithine, and aza-arginine.Mariam Traoré et al.Organic letters, 16(13), 3588-3591 (2014-06-25) Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET.Kaihang Wang et al.Nature chemistry, 6(5), 393-403 (2014-04-24) Aminocella lysinolytica gen. nov., sp. nov., a L-lysine-degrading, strictly anaerobic bacterium in the class Clostridia isolated from a methanogenic reactor of cattle farms.Atsuko Ueki et al.Archives of microbiology, 197(1), 97-104 (2014-12-03) Regulation of RNA polymerase II activation by histone acetylation in single living cells.Timothy J Stasevich et al.Nature, 516(7530), 272-275 (2014-09-26) Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases.Katrin Bagola et al.Molecular cell, 50(4), 528-539 (2013-05-15) Understanding the relationship between DNA methylation and histone lysine methylation.Nathan R Rose et al.Biochimica et biophysica acta, 1839(12), 1362-1372 (2014-02-25) Decoding the histone code: Role of H3K36me3 in mismatch repair and implications for cancer susceptibility and therapy.Guo-Min Li Cancer research, 73(21), 6379-6383 (2013-10-23) Bromodomain and extraterminal (BET) protein inhibition suppresses human T cell leukemia virus 1 (HTLV-1) Tax protein-mediated tumorigenesis by inhibiting nuclear factor κB (NF-κB) signaling.Xuewei Wu et al.The Journal of biological chemistry, 288(50), 36094-36105 (2013-11-06) Modulation of hydrophobic interactions by proximally immobilized ions.C Derek Ma et al.Nature, 517(7534), 347-350 (2015-01-17) Developmental enhancers are marked independently of zygotic Nodal signals in Xenopus.Rakhi Gupta et al.Developmental biology, 395(1), 38-49 (2014-09-11) Context dependency of Set1/COMPASS-mediated histone H3 Lys4 trimethylation.Janet L Thornton et al.Genes & development, 28(2), 115-120 (2014-01-10) Identification of ubiquitin-modified lysine residues and novel phosphorylation sites on eukaryotic initiation factor 2B epsilon.Alexander P Tuckow et al.Biochemical and biophysical research communications, 436(1), 41-46 (2013-05-28) SUMOylation regulates telomere length by targeting the shelterin subunit Tpz1(Tpp1) to modulate shelterin-Stn1 interaction in fission yeast.Keisuke Miyagawa et al.Proceedings of the National Academy of Sciences of the United States of America, 111(16), 5950-5955 (2014-04-09) Prostaglandin receptor EP₁-mediated differential degradation of cyclooxygenases involves a specific lysine residue.Almog Spector-Chotiner et al.Biochemical and biophysical research communications, 443(2), 738-742 (2013-12-18) Hyperactivation of the human plasma membrane Ca2+ pump PMCA h4xb by mutation of Glu99 to Lys.Luciana R Mazzitelli et al.The Journal of biological chemistry, 289(15), 10761-10768 (2014-03-04) Diversity-oriented synthesis of azapeptides with basic amino acid residues: aza-lysine, aza-ornithine, and aza-arginine.Mariam Traoré et al.Organic letters, 16(13), 3588-3591 (2014-06-25) Gene-specific methylation control of H3K9 and H3K36 on neurotrophic BDNF versus astroglial GFAP genes by KDM4A/C regulates neural stem cell differentiation.Anna Cascante et al.Journal of molecular biology, 426(20), 3467-3477 (2014-04-22) Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET.Kaihang Wang et al.Nature chemistry, 6(5), 393-403 (2014-04-24) Dietary consumption of advanced glycation end products and pancreatic cancer in the prospective NIH-AARP Diet and Health Study.Li Jiao et al.The American journal of clinical nutrition, 101(1), 126-134 (2014-12-21) Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins.Jennifer C Harr et al.The Journal of cell biology, 208(1), 33-52 (2015-01-07) Effect of caries removal techniques on the bond strength of adhesives to caries-affected primary dentin in vitro.E Yildiz et al.European journal of paediatric dentistry : official journal of European Academy of Paediatric Dentistry, 14(3), 209-214 (2013-12-04) [Arginine and lysine as products of basic carboxypeptidase activity associated with fibrinolysis].A A Zhloba et al.Biomeditsinskaia khimiia, 59(5), 570-577 (2014-02-01) Lysine-targeting specificity in ubiquitin and ubiquitin-like modification pathways.Francesca Mattiroli et al.Nature structural & molecular biology, 21(4), 308-316 (2014-04-05) Pyrrolysyl-tRNA synthetase: an ordinary enzyme but an outstanding genetic code expansion tool.Wei Wan et al.Biochimica et biophysica acta, 1844(6), 1059-1070 (2014-03-19) A role for SIRT2-dependent histone H3K18 deacetylation in bacterial infection.Haig A Eskandarian et al.Science (New York, N.Y.), 341(6145), 1238858-1238858 (2013-08-03) Glutathione-mediated reversibility of covalent modification of ubiquitin carboxyl-terminal hydrolase L1 by 1,2-naphthoquinone through Cys152, but not Lys4.Takashi Toyama et al.Chemico-biological interactions, 214, 41-48 (2014-03-04) Aminocella lysinolytica gen. nov., sp. nov., a L-lysine-degrading, strictly anaerobic bacterium in the class Clostridia isolated from a methanogenic reactor of cattle farms.Atsuko Ueki et al.Archives of microbiology, 197(1), 97-104 (2014-12-03) Pharmacological correction of gating defects in the voltage-gated Ca(v)2.1 Ca²⁺ channel due to a familial hemiplegic migraine mutation.Akira Inagaki et al.Neuron, 81(1), 91-102 (2014-01-15) Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia.Panagiotis Ntziachristos et al.Nature, 514(7523), 513-517 (2014-08-19) Towards understanding methyllysine readout.Catherine A Musselman et al.Biochimica et biophysica acta, 1839(8), 686-693 (2014-04-15) SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.Jeongsoon Park et al.Molecular cell, 50(6), 919-930 (2013-06-29) Dimeric Ube2g2 simultaneously engages donor and acceptor ubiquitins to form Lys48-linked ubiquitin chains.Weixiao Liu et al.The EMBO journal, 33(1), 46-61 (2013-12-25) Methylation: a multifaceted modification - looking at transcription and beyond.Johnathan R Whetstine Biochimica et biophysica acta, 1839(12), 1351-1352 (2014-09-17) Pharmacological correction of gating defects in the voltage-gated Ca(v)2.1 Ca²⁺ channel due to a familial hemiplegic migraine mutation.Akira Inagaki et al.Neuron, 81(1), 91-102 (2014-01-15) Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia.Panagiotis Ntziachristos et al.Nature, 514(7523), 513-517 (2014-08-19) Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis.Monica Di Giacomo et al.Molecular cell, 50(4), 601-608 (2013-05-28) A method for systematic mapping of protein lysine methylation identifies functions for HP1β in DNA damage response.Huadong Liu et al.Molecular cell, 50(5), 723-735 (2013-05-28) The parallel reaction monitoring method contributes to a highly sensitive polyubiquitin chain quantification.Hikaru Tsuchiya et al.Biochemical and biophysical research communications, 436(2), 223-229 (2013-06-04) Histone H3 lysine 4 trimethylation regulates cotranscriptional H2A variant exchange by Tip60 complexes to maximize gene expression.Thomas Kusch et al.Proceedings of the National Academy of Sciences of the United States of America, 111(13), 4850-4855 (2014-03-19) Molecular basis for substrate recognition by lysine methyltransferases and demethylases.Paul A Del Rizzo et al.Biochimica et biophysica acta, 1839(12), 1404-1415 (2014-06-21) Sumoylated human histone H4 prevents chromatin compaction by inhibiting long-range internucleosomal interactions.Abhinav Dhall et al.The Journal of biological chemistry, 289(49), 33827-33837 (2014-10-09) Transdifferentiation. Sequential histone-modifying activities determine the robustness of transdifferentiation.Steven Zuryn et al.Science (New York, N.Y.), 345(6198), 826-829 (2014-08-16) Functional lysine modification by an intrinsically reactive primary glycolytic metabolite.Raymond E Moellering et al.Science (New York, N.Y.), 341(6145), 549-553 (2013-08-03) The bromodomain protein Brd4 insulates chromatin from DNA damage signalling.Scott R Floyd et al.Nature, 498(7453), 246-250 (2013-06-04) PPARγ E3 ubiquitin ligase regulates MUC1-C oncoprotein stability.Y Hou et al.Oncogene, 33(49), 5619-5625 (2013-12-03) Dendritic structural degeneration is functionally linked to cellular hyperexcitability in a mouse model of Alzheimer's disease.Zuzana Šišková et al.Neuron, 84(5), 1023-1033 (2014-12-03) Ketoprofen is more effective than diclofenac after oral surgery when used as a preemptive analgesic: a pilot study.Grace Carolaine Esquivel Velásquez et al.Journal of oral & facial pain and headache, 28(2), 153-158 (2014-05-14) Different activities of the conserved lysine residues in the double-stranded RNA binding domains of RNA helicase A in vitro and in the cell.Li Xing et al.Biochimica et biophysica acta, 1840(7), 2234-2243 (2014-04-15) Theta-gamma-modulated synaptic currents in hippocampal granule cells in vivo define a mechanism for network oscillations.Alejandro Javier Pernía-Andrade et al.Neuron, 81(1), 140-152 (2013-12-18) Method for detecting the reactivity of chemicals towards peptides as an alternative test method for assessing skin sensitization potential.Sun-A Cho et al.Toxicology letters, 225(1), 185-191 (2013-12-24) Specific expression of k63-linked ubiquitination of calmodulin-like protein 5 in breast cancer of premenopausal patients.Manuel Debald et al.Journal of cancer research and clinical oncology, 139(12), 2125-2132 (2013-10-23) RLIM is dispensable for X-chromosome inactivation in the mouse embryonic epiblast.JongDae Shin et al.Nature, 511(7507), 86-89 (2014-05-30) Hst3 is turned over by a replication stress-responsive SCF(Cdc4) phospho-degron.Ellen R Edenberg et al.Proceedings of the National Academy of Sciences of the United States of America, 111(16), 5962-5967 (2014-04-10) Lys751Gln XPD and Arg399Gln XRCC1 in Romanians. Association with sporadic colorectal cancer risk and different stages of carcinomas.L M Procopciuc et al.Chirurgia (Bucharest, Romania : 1990), 108(5), 711-718 (2013-10-26) Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes.Alexander Leitner et al.Proceedings of the National Academy of Sciences of the United States of America, 111(26), 9455-9460 (2014-06-19) Z α1-antitrypsin confers a proinflammatory phenotype that contributes to chronic obstructive pulmonary disease.Samuel Alam et al.American journal of respiratory and critical care medicine, 189(8), 909-931 (2014-03-07) Histone lysine methylation and chromatin replication.Carlos Rivera et al.Biochimica et biophysica acta, 1839(12), 1433-1439 (2014-04-02) High-nutrition biscuits to increase animal protein in diets of HIV-infected Kenyan women and their children: a study in progress.Judith Ernst et al.Food and nutrition bulletin, 35(4 Suppl), S198-S204 (2015-02-03) Histone deacetylases inhibitor trichostatin A modulates the extracellular release of APE1/Ref-1.Sunga Choi et al.Biochemical and biophysical research communications, 435(3), 403-407 (2013-05-15) Examining the impact of gene variants on histone lysine methylation.Capucine Van Rechem et al.Biochimica et biophysica acta, 1839(12), 1463-1476 (2014-05-27) SIRT5 desuccinylates and activates SOD1 to eliminate ROS.Zhi-Feng Lin et al.Biochemical and biophysical research communications, 441(1), 191-195 (2013-10-22) 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark.Amélie Fradet-Turcotte et al.Nature, 499(7456), 50-54 (2013-06-14) Evidence for lysine acetylation in the coat protein of a polerovirus.Michelle Cilia et al.The Journal of general virology, 95(Pt 10), 2321-2327 (2014-06-19) Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study.HaiYing Chen et al.Lancet (London, England), 383(9918), 714-721 (2014-02-11) Ubc9 sumoylation controls SUMO chain formation and meiotic synapsis in Saccharomyces cerevisiae.Helene Klug et al.Molecular cell, 50(5), 625-636 (2013-05-07) In the matter of certain amino acid formulations: unreviewed initial determination (1983) A lysine-rich membrane-associated PHISTb protein involved in alteration of the cytoadhesive properties of Plasmodium falciparum-infected red blood cells.Nicholas I Proellocks et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(7), 3103-3113 (2014-04-08) Hitting the 'mark': interpreting lysine methylation in the context of active transcription.Glenn G Wozniak et al.Biochimica et biophysica acta, 1839(12), 1353-1361 (2014-03-19) Merlin sumoylation is required for its tumor suppressor activity.Q Qi et al.Oncogene, 33(41), 4893-4903 (2013-10-30) Crystal structures and kinetics of Type III 3-phosphoglycerate dehydrogenase reveal catalysis by lysine.Rohit K Singh et al.The FEBS journal, 281(24), 5498-5512 (2014-10-09) Effect of short peptides containing lysine and epsilon-aminocaproic acid on fibrinolytic activity of plasmin and topoisomerase II action on supercoiled DNA.Krystyna Midura-Nowaczek et al.Acta poloniae pharmaceutica, 70(3), 431-434 (2013-06-14) PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum.Lubin Jiang et al.Nature, 499(7457), 223-227 (2013-07-05) A central role for intermolecular dityrosine cross-linking of fibrinogen in high molecular weight advanced oxidation protein product (AOPP) formation.Graziano Colombo et al.Biochimica et biophysica acta, 1850(1), 1-12 (2014-10-05) Effect of chemomechanical caries removal on bonding of self-etching adhesives to caries-affected dentin.Hamdi Hosni Hamdan Hamama et al.The journal of adhesive dentistry, 16(6), 507-516 (2014-12-18) Dietary lysine affects chickens from local Chinese pure lines and their reciprocal crosses.Juan Li et al.Poultry science, 92(6), 1683-1689 (2013-05-21) Transcriptional regulation of the albumin gene depends on the removal of histone methylation marks by the FAD-dependent monoamine oxidase lysine-specific demethylase 1 in HepG2 human hepatocarcinoma cells.Dandan Liu et al.The Journal of nutrition, 144(7), 997-1001 (2014-04-20) GCN5 is involved in regulation of immunoglobulin heavy chain gene expression in immature B cells.Hidehiko Kikuchi et al.Gene, 544(1), 19-24 (2014-04-22) Renal ApoA-1 amyloidosis with Glu34Lys mutation and intra-amyloid lipid accumulation.Nicole K Andeen et al.Journal of the American Society of Nephrology : JASN, 25(12), 2703-2705 (2014-06-14) Identification of lysine residues in the Borrelia burgdorferi DbpA adhesin required for murine infection.Danielle E Fortune et al.Infection and immunity, 82(8), 3186-3198 (2014-05-21) Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling.Hans-Martin Herz et al.Science (New York, N.Y.), 345(6200), 1065-1070 (2014-08-30) An unexpected journey: lysine methylation across the proteome.Kaitlyn E Moore et al.Biochimica et biophysica acta, 1839(12), 1395-1403 (2014-02-25) Ubiquitylation of autophagy receptor Optineurin by HACE1 activates selective autophagy for tumor suppression.Zhengzhao Liu et al.Cancer cell, 26(1), 106-120 (2014-07-16) Importance of a Lys113-Glu195 intermonomer ionic bond in F-actin stabilization and regulation by yeast formins Bni1p and Bnr1p.Kuo-Kuang Wen et al.The Journal of biological chemistry, 288(26), 19140-19153 (2013-05-09) A cascade of histone modifications induces chromatin condensation in mitosis.Bryan J Wilkins et al.Science (New York, N.Y.), 343(6166), 77-80 (2014-01-05) SUMOylation and deimination of proteins: two epigenetic modifications involved in Giardia encystation.Cecilia V Vranych et al.Biochimica et biophysica acta, 1843(9), 1805-1817 (2014-04-23) Transient contacts on the exterior of the HK97 procapsid that are essential for capsid assembly.Dan-ju Tso et al.Journal of molecular biology, 426(10), 2112-2129 (2014-03-25) KAT5 tyrosine phosphorylation couples chromatin sensing to ATM signalling.Abderrahmane Kaidi et al.Nature, 498(7452), 70-74 (2013-05-28) Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo.Edward Rockenstein et al.Brain : a journal of neurology, 137(Pt 5), 1496-1513 (2014-03-26) The gene silencing transcription factor REST represses miR-132 expression in hippocampal neurons destined to die.Jee-Yeon Hwang et al.Journal of molecular biology, 426(20), 3454-3466 (2014-08-12) Characterization of THB1, a Chlamydomonas reinhardtii truncated hemoglobin: linkage to nitrogen metabolism and identification of lysine as the distal heme ligand.Johnson EA, Rice SL, Preimesberger MR, et al. Biochemistry, 53(28), 4573-4589 (2014) Convergent evolution of chromatin modification by structurally distinct enzymes: comparative enzymology of histone H3 Lys²⁷ methylation by human polycomb repressive complex 2 and vSET.Brooke M Swalm et al.The Biochemical journal, 453(2), 241-247 (2013-05-18) Antigen-specific immune responses and clinical outcome after vaccination with glioma-associated antigen peptides and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in children with newly diagnosed malignant brainstem and nonbrainstem gliomas.Ian F Pollack et al.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(19), 2050-2058 (2014-06-04) Acetylation: a lysine modification with neuroprotective effects in ischemic retinal degeneration.Oday Alsarraf et al.Experimental eye research, 127, 124-131 (2014-07-30) Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO.Juan Liu et al.Nature immunology, 15(7), 612-622 (2014-05-27) Inhibition of PKR protects against tunicamycin-induced apoptosis in neuroblastoma cells.Lauren S Vaughn et al.Gene, 536(1), 90-96 (2013-12-18) Inhibition of histone binding by supramolecular hosts.Hillary F Allen et al.The Biochemical journal, 459(3), 505-512 (2014-03-01) AC/D(eA)C rocks the polymerases.Clélia Laitem et al.Molecular cell, 52(3), 287-288 (2013-11-12) Acetylation: a lysine modification with neuroprotective effects in ischemic retinal degeneration.Oday Alsarraf et al.Experimental eye research, 127, 124-131 (2014-07-30) The ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substrates.Kenneth Matthew Scaglione et al.The Journal of biological chemistry, 288(26), 18784-18788 (2013-05-23) The enhancer and promoter landscape of human regulatory and conventional T-cell subpopulations.Christian Schmidl et al.Blood, 123(17), e68-e78 (2014-03-29) Sumoylation of influenza A virus nucleoprotein is essential for intracellular trafficking and virus growth.Qinglin Han et al.Journal of virology, 88(16), 9379-9390 (2014-06-13) Botulinum neurotoxin G binds synaptotagmin-II in a mode similar to that of serotype B: tyrosine 1186 and lysine 1191 cause its lower affinity.Gesche Willjes et al.Biochemistry, 52(22), 3930-3938 (2013-05-08) Optimization of response surface and neural network models in conjugation with desirability function for estimation of nutritional needs of methionine, lysine, and threonine in broiler chickens.Mehran Mehri Poultry science, 93(7), 1862-1867 (2014-05-09) The F-box protein FBXO7 positively regulates bone morphogenetic protein-mediated signaling through Lys-63-specific ubiquitination of neurotrophin receptor-interacting MAGE (NRAGE).Jengmin Kang et al.Cellular and molecular life sciences : CMLS, 72(1), 181-195 (2014-06-21) Histone lysine-specific demethylase 1 (LSD1) protein is involved in Sal-like protein 4 (SALL4)-mediated transcriptional repression in hematopoietic stem cells.Li Liu et al.The Journal of biological chemistry, 288(48), 34719-34728 (2013-10-29) Hydrogen exchange differences between chemoreceptor signaling complexes localize to functionally important subdomains.Seena S Koshy et al.Biochemistry, 53(49), 7755-7764 (2014-11-25) Natural variation in the heparan sulfate binding domain of the eastern equine encephalitis virus E2 glycoprotein alters interactions with cell surfaces and virulence in mice.Christina L Gardner et al.Journal of virology, 87(15), 8582-8590 (2013-05-31) Acetylation of cyclin-dependent kinase 5 is mediated by GCN5.Juhyung Lee et al.Biochemical and biophysical research communications, 447(1), 121-127 (2014-04-08) Dietary intake of advanced glycation end products did not affect endothelial function and inflammation in healthy adults in a randomized controlled trial.Richard D Semba et al.The Journal of nutrition, 144(7), 1037-1042 (2014-04-20) Type AII lantibiotic bovicin HJ50 with a rare disulfide bond: structure, structure-activity relationships and mode of action.Jie Zhang et al.The Biochemical journal, 461(3), 497-508 (2014-05-13) Development of a novel long-acting antidiabetic FGF21 mimetic by targeted conjugation to a scaffold antibody.Jie Huang et al.The Journal of pharmacology and experimental therapeutics, 346(2), 270-280 (2013-05-31) Keeping them all together: β-propeller domains in histone methyltransferase complexes.Elisa Bergamin et al.Journal of molecular biology, 426(20), 3363-3375 (2014-05-24) Mammalian protein arginine methyltransferase 7 (PRMT7) specifically targets RXR sites in lysine- and arginine-rich regions.You Feng et al.The Journal of biological chemistry, 288(52), 37010-37025 (2013-11-20) LSD1 regulates pluripotency of embryonic stem/carcinoma cells through histone deacetylase 1-mediated deacetylation of histone H4 at lysine 16.Feng Yin et al.Molecular and cellular biology, 34(2), 158-179 (2013-11-06) Lysine partitioning in broiler breeders is not affected by energy or protein intake when fed at current industry levels.R D Ekmay et al.Poultry science, 93(7), 1737-1744 (2014-05-28) Patched-1 proapoptotic activity is downregulated by modification of K1413 by the E3 ubiquitin-protein ligase Itchy homolog.Xiaole L Chen et al.Molecular and cellular biology, 34(20), 3855-3866 (2014-08-06) A new type of protein lysine methyltransferase trimethylates Lys-79 of elongation factor 1A.Maria C Dzialo et al.Biochemical and biophysical research communications, 455(3-4), 382-389 (2014-12-03) Acetylation of RNA polymerase II regulates growth-factor-induced gene transcription in mammalian cells.Sebastian Schröder et al.Molecular cell, 52(3), 314-324 (2013-11-12) Diels-Alder reaction-triggered bioorthogonal protein decaging in living cells.Jie Li et al.Nature chemical biology, 10(12), 1003-1005 (2014-11-05) CG hypomethylation in Lsh-/- mouse embryonic fibroblasts is associated with de novo H3K4me1 formation and altered cellular plasticity.Weishi Yu et al.Proceedings of the National Academy of Sciences of the United States of America, 111(16), 5890-5895 (2014-04-09)
备注

Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.

Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1).

名称 CAS号

相关产品

相关资讯

热门标签
询 单
请 填 写 相 关 信 息
产品信息
产品名称
别名
CAS号
结构式 上传
联系方式
公司
联系人
电话
邮箱
内容
提交