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3,4,5-Trimethoxybenzohydrazide | CAS:3291-03-0
3,4,5-Trimethoxybenzohydrazide
  • 名称:3,4,5-三甲氧基苯甲酰肼 | 3,4,5-Trimethoxybenzohydrazide
  • CAS号:3291-03-0
  • 别名:3,4,5-Trimethoxybenzoic acid hydrazide; 3,4,5-Trimethoxybenzoic hydrazide; 3,4,5-Trimethoxybenzoylhydrazide; NSC 39075
  • 分子式:C10H14N2O4
  • 分子量:226.23
  • EINESC号:221-954-6

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物理化学性质

熔点 158-160 ºC
密度 1.197

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Para-phenylenediamine-specific lymphocyte activation test: a sensitive in vitro assay to detect para-phenylenediamine sensitization in patients with severe allergic reactions.Manfred Kneilling et al.Experimental dermatology, 19(5), 435-441 (2010-02-02) p-Phenylenediamine and other hair dye sensitizers in Spain.Kerem Yazar et al.Contact dermatitis, 66(1), 27-32 (2011-11-17) Effect of 4 toluene diamine isomers on murine testicular DNA synthesis.E J Greene et al.Mutation research, 91(1), 75-79 (1981-01-01) Severe aplastic anaemia following the use of hair dye: report of two cases and review of literature.J E Hopkins et al.Postgraduate medical journal, 61(721), 1003-1005 (1985-11-01) Determination of 2,5-toluylenediamine (2,5-TDA) and aromatic amines in urine after personal application of hair dyes: kinetics and doses.Thomas Schettgen et al.Archives of toxicology, 85(2), 127-133 (2010-06-16) [Allergic reaction form of middle ear mucosa. An animal experiment study].H Enzmann et al.Laryngo- rhino- otologie, 69(4), 208-212 (1990-04-01) Lack of an indication of mutagenic effects of dinitrotoluenes and diaminotoluenes in mice.E R Soares et al.Environmental mutagenesis, 2(2), 111-124 (1980-01-01) Cross-reactions among hair dye allergens.David A Basketter et al.Cutaneous and ocular toxicology, 28(3), 104-106 (2009-06-26) Final amended report of the safety assessment of toluene-2,5-diamine, toluene-2,5-diamine sulfate, and toluene-3,4-diamine as used in cosmetics.Christina L Burnett et al.International journal of toxicology, 29(3 Suppl), 61S-83S (2010-05-22) Mutagenicity and toxicity studies of p-phenylenediamine and its derivatives.K T Chung et al.Toxicology letters, 81(1), 23-32 (1995-11-01) Experimental study on skin sensitization potencies and cross-reactivities of hair-dye-related chemicals in guinea pigs.Z Xie et al.Contact dermatitis, 42(5), 270-275 (2000-05-02) Determination of diaminotoluene isomers by gas chromatography.L E Brydia et al.IARC scientific publications, (40)(40), 235-242 (1981-01-01) Hair dye-sensitized hairdressers: the cross-reaction pattern with new generation hair dyes.Rolf Fautz et al.Contact dermatitis, 46(6), 319-324 (2002-08-23) Primary sensitization to toluene-2,5-diamine giving rise to early positive patch reaction to p-phenylenediamine and late to toluene-2,5-diamine.A Bregnhøj et al.Contact dermatitis, 59(3), 189-190 (2008-09-02) Long-term toxicity studies on oxidation hair dyes.C Burnett et al.Food and cosmetics toxicology, 13(3), 353-357 (1975-06-01) The hair dyes PPD and PTD fail to induce a T(H)2 immune response following repeated topical application in BALB/c mice.Helga Rothe et al.Journal of immunotoxicology, 8(1), 46-55 (2011-02-09) Alternative hair-dye products for persons allergic to para-phenylenediamine.Andrew Scheman et al.Dermatitis : contact, atopic, occupational, drug, 22(4), 189-192 (2011-07-26) Allergic contact dermatitis from toluene-2,5-diamine in a cream dye for eyelashes and eyebrows--quantitative exposure assessment.Heidi Søsted et al.Contact dermatitis, 57(3), 195-196 (2007-08-08) Severe inflammatory and keloidal, allergic reaction due to para-phenylenediamine in temporary tattoos.Suhan Gunasti et al.Indian journal of dermatology, venereology and leprology, 76(2), 165-167 (2010-03-17) Occupational asthma, rhinitis, and contact urticaria caused by oxidative hair dyes in hairdressers.Eva Helaskoski et al.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 112(1), 46-52 (2013-12-18) Hair dye contact allergy: quantitative exposure assessment of selected products and clinical cases.Heidi Søsted et al.Contact dermatitis, 50(6), 344-348 (2004-07-28) Toluene-2,5-diamine may be an isolated allergy in individuals sensitized by permanent hair dye.S M Winhoven et al.Contact dermatitis, 57(3), 193-193 (2007-08-08) Reactivity of in vitro activated human T lymphocytes to p-phenylenediamine and related substances.Claudia Skazik et al.Contact dermatitis, 59(4), 203-211 (2008-10-11) Potent skin sensitizers in oxidative hair dye products on the Swedish market.Kerem Yazar et al.Contact dermatitis, 61(5), 269-275 (2009-11-03) Internal exposure of hairdressers to permanent hair dyes: a biomonitoring study using urinary aromatic diamines as biomarkers of exposure.M Gube et al.International archives of occupational and environmental health, 84(3), 287-292 (2010-05-06) Interaction with the aromatic hydrocarbon receptor, CYP1A induction, and mutagenicity of a series of diaminotoluenes: implications for their carcinogenicity.Y L Cheung et al.Toxicology and applied pharmacology, 139(1), 203-211 (1996-07-01)
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