熔点	46-48 ºC**
沸点	138-142 ºC (20 Torr)**
闪点	101.8±16.4 ºC, 计算值*
密度	1.075±0.06 g/cm3 (20 º

没有数据	没有数据

来源	SDS样本
没有数据	没有数据

产品合成路线

更多

名称	CAS号

更多

文章

同行评议文献

In vivo and in vitro studies of the role of the adrenergic system and follicular wall contractility in the pathogenesis and resolution of bovine follicular cysts.A Rizzo et al.Theriogenology, 76(8), 1526-1531 (2011-08-02) Structure of a beta1-adrenergic G-protein-coupled receptor.Tony Warne et al.Nature, 454(7203), 486-491 (2008-07-03) Hybrid molecular mechanics/coarse-grained simulations for structural prediction of G-protein coupled receptor/ligand complexes.Michael Leguèbe et al.PloS one, 7(10), e47332-e47332 (2012-10-25) Betablockers at work: the crystal structure of the beta2-adrenergic receptor.Felix Hausch Angewandte Chemie (International ed. in English), 47(18), 3314-3316 (2008-03-19) CH/π hydrogen bonds play a role in ligand recognition and equilibrium between active and inactive states of the β2 adrenergic receptor: an ab initio fragment molecular orbital (FMO) study.Tomonaga Ozawa et al.Bioorganic & medicinal chemistry, 19(17), 5231-5237 (2011-08-09) Structure and function of an irreversible agonist-β(2) adrenoceptor complex.Daniel M Rosenbaum et al.Nature, 469(7329), 236-240 (2011-01-14) Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.Michael P Bokoch et al.Nature, 463(7277), 108-112 (2010-01-08) Ligand-dependent perturbation of the conformational ensemble for the GPCR β2 adrenergic receptor revealed by HDX.Graham M West et al.Structure (London, England : 1993), 19(10), 1424-1432 (2011-09-06) Functional competence of a partially engaged GPCR-β-arrestin complex.Punita Kumari et al.Nature communications, 7, 13416-13416 (2016-11-09) Structure of a beta1-adrenergic G-protein-coupled receptor.Tony Warne et al.Nature, 454(7203), 486-491 (2008-07-03) Hybrid molecular mechanics/coarse-grained simulations for structural prediction of G-protein coupled receptor/ligand complexes.Michael Leguèbe et al.PloS one, 7(10), e47332-e47332 (2012-10-25) High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists.Yveline Henchoz et al.Journal of medicinal chemistry, 51(3), 396-399 (2008-01-15) High-Affinity Functional Fluorescent Ligands for Human β-Adrenoceptors.Gyuzel Y Mitronova et al.Scientific reports, 7(1), 12319-12319 (2017-09-28) Validation of a method for sedatives and β-blockers determination in swine, bovine and equine kidney using liquid chromatography coupled with tandem mass spectrometry.Lenise Guimarães de Oliveira et al.Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 34(1), 32-39 (2016-11-22) On the applicability of GPCR homology models to computer-aided drug discovery: a comparison between in silico and crystal structures of the beta2-adrenergic receptor.Stefano Costanzi Journal of medicinal chemistry, 51(10), 2907-2914 (2008-04-30) Determination of residues of carazolol and a number of tranquilizers in swine kidney by high-performance liquid chromatography with ultraviolet and fluorescence detection.Keukens HJ and Aerts MML Journal of Chromatography A, 464, 149- 161 (1991) Molecular dynamics simulations of the effect of the G-protein and diffusible ligands on the β2-adrenergic receptor.Angela Goetz et al.Journal of molecular biology, 414(4), 611-623 (2011-11-01) Selective structure-based virtual screening for full and partial agonists of the beta2 adrenergic receptor.Chris de Graaf et al.Journal of medicinal chemistry, 51(16), 4978-4985 (2008-08-06) Separation of enantiomers of chiral basic drugs with amylose- and cellulose- phenylcarbamate-based chiral columns in acetonitrile and aqueous-acetonitrile in high-performance liquid chromatography with a focus on substituent electron-donor and electron-acceptor effects.Iza Matarashvili et al.Journal of chromatography. A, 1624, 461218-461218 (2020-06-17) Dynamics of the beta2-adrenergic G-protein coupled receptor revealed by hydrogen-deuterium exchange.Xi Zhang et al.Analytical chemistry, 82(3), 1100-1108 (2010-01-12) Use of the X-ray structure of the beta2-adrenergic receptor for drug discovery. Part 2: Identification of active compounds.Michael Sabio et al.Bioorganic & medicinal chemistry letters, 18(20), 5391-5395 (2008-10-03) [Determination of azaperone and carazolol residues in animals kidney using LC-MS/MS method].Iwona Zawadzka et al.Roczniki Panstwowego Zakladu Higieny, 60(1), 19-23 (2009-07-08) Biochemistry. Signaling across the cell membrane.Rama Ranganathan Science (New York, N.Y.), 318(5854), 1253-1254 (2007-11-24) Ligand entry and exit pathways in the beta2-adrenergic receptor.Ting Wang et al.Journal of molecular biology, 392(4), 1102-1115 (2009-08-12) Multiclass screening method to detect more than fifty banned substances in bovine bile and urine.Simone Moretti et al.Analytica chimica acta, 1032, 56-67 (2018-08-26) Ligand-specific interactions modulate kinetic, energetic, and mechanical properties of the human β2 adrenergic receptor.Michael Zocher et al.Structure (London, England : 1993), 20(8), 1391-1402 (2012-07-04) Facile radiosynthesis of fluorine-18 labeled beta-blockers. Synthesis, radiolabeling, and ex vivo biodistribution of [18F]-(2S and 2R)-1-(1-fluoropropan-2-ylamino)-3-(m-tolyloxy)propan-2-ol.Karin A Stephenson et al.Journal of medicinal chemistry, 51(16), 5093-5100 (2008-07-29) Trimethylsilyl reporter groups for NMR studies of conformational changes in G protein-coupled receptors.Wanhui Hu et al.FEBS letters, 593(10), 1113-1121 (2019-04-07) Determination of tranquilisers and carazolol residues in animal tissue using high-performance liquid chromatography with electrochemical detection.Rose MD and Shearer G Journal of Chromatography A, 624(1-2), 471- 477 (1992) Identifying conformational changes of the beta(2) adrenoceptor that enable accurate prediction of ligand/receptor interactions and screening for GPCR modulators.Kimberly A Reynolds et al.Journal of computer-aided molecular design, 23(5), 273-288 (2009-01-17) Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes.Vsevolod Katritch et al.Journal of molecular recognition : JMR, 22(4), 307-318 (2009-04-09) Crystallizing thinking about the beta2-adrenergic receptor.Arun K Shukla et al.Molecular pharmacology, 73(5), 1333-1338 (2008-02-02) Determination of 15 sedative residues in mutton by rapid resolution liquid chromatography-tandem mass spectrometry.Jinmei Wei et al.Journal of the science of food and agriculture, 95(3), 598-606 (2014-06-21) Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.Bruno Bard et al.Journal of medicinal chemistry, 52(10), 3416-3419 (2009-04-29) Analysis of 27 β-Blockers and Metabolites in Milk Powder by High Performance Liquid Chromatography Coupled to Quadrupole Orbitrap High-Resolution Mass Spectrometry.Jian-Qiao Cheng et al.Molecules (Basel, Switzerland), 24(4) (2019-03-03) FoldGPCR: structure prediction protocol for the transmembrane domain of G protein-coupled receptors from class A.Mayako Michino et al.Proteins, 78(10), 2189-2201 (2010-06-15) Lambing rates and litter size following carazolol administration prior to insemination in Kivircik ewes.Mehmet Can Gündüz et al.Animal reproduction science, 118(1), 32-36 (2009-07-10) Mechanism of intracellular allosteric βXiangyu Liu et al.Nature, 548(7668), 480-484 (2017-08-17) Evaluation of bi-functionalized mesoporous silicas as reversed phase/cation-exchange mixed-mode sorbents for multi-residue solid phase extraction of veterinary drug residues in meat samples.Natalia Casado et al.Talanta, 165, 223-230 (2017-02-06) X-ray structure breakthroughs in the GPCR transmembrane region.Sid Topiol et al.Biochemical pharmacology, 78(1), 11-20 (2009-05-19) Constitutive phospholipid scramblase activity of a G protein-coupled receptor.Michael A Goren et al.Nature communications, 5, 5115-5115 (2014-10-09) Prooxidant action of carazolol in the Fenton-like reaction.Irena Kruk et al.Luminescence : the journal of biological and chemical luminescence, 26(6), 429-433 (2010-09-16)

备注