没有数据	没有数据

没有数据	没有数据

来源	SDS样本
Sigma-Aldrich	浏览或下载
TCI	浏览或下载
Matrix	浏览或下载

产品合成路线

更多

名称	CAS号

更多

文章

同行评议文献

Guanabenz interferes with ER stress and exerts protective effects in cardiac myocytes.Christiane Neuber et al.PloS one, 9(6), e98893-e98893 (2014-06-04) G protein-coupled receptor signalling potentiates the osmo-mechanical activation of TRPC5 channels.Imane Jemal et al.Pflugers Archiv : European journal of physiology, 466(8), 1635-1646 (2013-11-02) Sirtuin-1 ameliorates cadmium-induced endoplasmic reticulum stress and pyroptosis through XBP-1s deacetylation in human renal tubular epithelial cells.Xin Chou et al.Archives of toxicology, 93(4), 965-986 (2019-02-24) Novel Protein Kinase C-Mediated Control of Orai1 Function in Invasive Melanoma.Robert Hooper et al.Molecular and cellular biology, 35(16), 2790-2798 (2015-06-10) Loss of MCU prevents mitochondrial fusion in G1-S phase and blocks cell cycle progression and proliferation.Olha M Koval et al.Science signaling, 12(579) (2019-05-02) Store-operated Ca(2+) entry in rhabdomyosarcoma cells.Evi Schmid et al.Biochemical and biophysical research communications, 477(1), 129-136 (2016-06-14) Functional Translatome Proteomics Reveal Converging and Dose-Dependent Regulation by mTORC1 and eIF2α.Kevin Klann et al.Molecular cell, 77(4), 913-925 (2019-12-10) Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet.Naoki Tanaka et al.Biochimica et biophysica acta, 1852(7), 1242-1252 (2015-03-05) An endoplasmic reticulum stress-initiated sphingolipid metabolite, ceramide-1-phosphate, regulates epithelial innate immunity by stimulating β-defensin production.Young-Il Kim et al.Molecular and cellular biology, 34(24), 4368-4378 (2014-10-15) ATF6α Activation Enhances Survival against Chemotherapy and Serves as a Prognostic Indicator in Osteosarcoma.Suma Yarapureddy et al.Neoplasia (New York, N.Y.), 21(6), 516-532 (2019-04-28) Catestatin attenuates endoplasmic reticulum induced cell apoptosis by activation type 2 muscarinic acetylcholine receptor in cardiac ischemia/reperfusion.Feng Liao et al.Scientific reports, 5, 16590-16590 (2015-11-17) In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in Plasmodium falciparum strains.Oyindamola O Abiodun et al.Malaria journal, 12, 43-43 (2013-02-02) TRPV4 mediates the CaPamma D Arora et al.Journal of cell science, 130(13), 2196-2208 (2017-05-21) Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression.Jonathan Merola et al.JCI insight, 4(20) (2019-09-19) Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex.Ryan S D'Souza et al.eLife, 9 (2020-04-03) Applying linear interaction energy method for rational design of noncompetitive allosteric inhibitors of the sarco- and endoplasmic reticulum calcium-ATPase.Pratap Singh et al.Journal of medicinal chemistry, 48(8), 3005-3014 (2005-04-15) GRAF2, WDR44, and MICAL1 mediate Rab8/10/11-dependent export of E-cadherin, MMP14, and CFTR ΔF508.Safa Lucken-Ardjomande Häsler et al.The Journal of cell biology, 219(5) (2020-04-29) Detecting In-Situ oligomerization of engineered STIM1 proteins by diffraction-limited optical imaging.Prasanna Srinivasan PloS one, 14(3), e0213655-e0213655 (2019-03-26) Saururus chinensis Baill induces apoptosis through endoplasmic reticulum stress in HepG2 hepatocellular carcinoma cells.Ah Young Lee et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 83, 183-192 (2015-06-28) Translation of dipeptide repeat proteins from the C9ORF72 expanded repeat is associated with cellular stress.Yoshifumi Sonobe et al.Neurobiology of disease, 116, 155-165 (2018-05-25) Activation of TRPV1 channel antagonizes diabetic nephropathy through inhibiting endoplasmic reticulum-mitochondria contact in podocytes.Xiao Wei et al.Metabolism: clinical and experimental, 105, 154182-154182 (2020-02-18) Calreticulin Ins5 and Del52 mutations impair unfolded protein and oxidative stress responses in K562 cells expressing CALR mutants.Simona Salati et al.Scientific reports, 9(1), 10558-10558 (2019-07-25) The 2-aminoethoxydiphenyl borate analog, DPB161 blocks store-operated CaKunkun Xia et al.Oncotarget, 8(37), 61551-61560 (2017-10-06) Activation of unfolded protein response pathway during infectious salmon anemia virus (ISAV) infection in vitro an in vivo.Arturas Kavaliauskis et al.Developmental and comparative immunology, 54(1), 46-54 (2015-08-26) Dimethyl fumarate alters intracellular Ca2+ handling in immune cells by redox-mediated pleiotropic effects.Ann-Kathrin Herrmann et al.Free radical biology & medicine, 141, 338-347 (2019-07-08) The role of calcium in VDAC1 oligomerization and mitochondria-mediated apoptosis.Nurit Keinan et al.Biochimica et biophysica acta, 1833(7), 1745-1754 (2013-04-02) JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia.Kaan Boztug et al.Nature genetics, 46(9), 1021-1027 (2014-08-19) COX-2- and endoplasmic reticulum stress-independent induction of ULBP-1 and enhancement of sensitivity to NK cell-mediated cytotoxicity by celecoxib in colon cancer cells.So-Jung Kim et al.Experimental cell research, 330(2), 451-459 (2014-09-15) Acacetin blocks kv1.3 channels and inhibits human T cell activation.Ning Zhao et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 34(4), 1359-1372 (2014-10-11) Subverting ER-stress towards apoptosis by nelfinavir and curcumin coexposure augments docetaxel efficacy in castration resistant prostate cancer cells.Aditi Mathur et al.PloS one, 9(8), e103109-e103109 (2014-08-15) The Coronavirus Transmissible Gastroenteritis Virus Evades the Type I Interferon Response through IRE1α-Mediated Manipulation of the MicroRNA miR-30a-5p/SOCS1/3 Axis.Yanlong Ma et al.Journal of virology, 92(22) (2018-09-07) Calcium Signaling throughout the Toxoplasma gondii Lytic Cycle: A STUDY USING GENETICALLY ENCODED CALCIUM INDICATORS.Lucas Borges-Pereira et al.The Journal of biological chemistry, 290(45), 26914-26926 (2015-09-17) Upregulation of Orai1 and STIM1 expression as well as store-operated Ca2+ entry in ovary carcinoma cells by placental growth factor.Khalid N M Abdelazeem et al.Biochemical and biophysical research communications, 512(3), 467-472 (2019-03-25) Annexin A4 is a novel direct regulator of adenylyl cyclase type 5.Alexander Heinick et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(9), 3773-3787 (2015-05-30) Role of Calcium Signaling in GA101-Induced Cell Death in Malignant Human B Cells.Simon Latour et al.Cancers, 11(3) (2019-03-06) Endoplasmic reticulum stress up-regulates Nedd4-2 to induce autophagy.Hao Wang et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 30(7), 2549-2556 (2016-03-30) Biochemical Characterization and Allosteric Modulation by Magnesium of (Na+, K+)-ATPase Activity in the Gills of the Red Mangrove Crab Goniopsis cruentata (Brachyura, Grapsidae).Cintya M Moraes et al.The Journal of membrane biology, 253(3), 229-245 (2020-05-23) Increased serum CXCL1 and CXCL5 are linked to obesity, hyperglycemia, and impaired islet function.Craig S Nunemaker et al.The Journal of endocrinology, 222(2), 267-276 (2014-06-15) Function of Large and Small Platelets Differs, Depending on Extracellular Calcium Availability and Type of Inductor.Stefan Handtke et al.Thrombosis and haemostasis, 120(7), 1075-1086 (2020-06-12) Deficiency of the BiP cochaperone ERdj4 causes constitutive endoplasmic reticulum stress and metabolic defects.Jill M Fritz et al.Molecular biology of the cell, 25(4), 431-440 (2013-12-18) Endoplasmic reticulum stress in spinal and bulbar muscular atrophy: a potential target for therapy.Karli Montague et al.Brain : a journal of neurology, 137(Pt 7), 1894-1906 (2014-06-06) The Parkinson's disease-associated GPR37 receptor-mediated cytotoxicity is controlled by its intracellular cysteine-rich domain.Jorge Gandía et al.Journal of neurochemistry, 125(3), 362-372 (2013-02-13) Differential engagement of ORAI1 and TRPC1 in the induction of vimentin expression by different stimuli.Teneale A Stewart et al.Laboratory investigation; a journal of technical methods and pathology, 100(2), 224-233 (2019-06-28) P21-activated kinase 4 in pancreatic acinar cells is activated by numerous gastrointestinal hormones/neurotransmitters and growth factors by novel signaling, and its activation stimulates secretory/growth cascades.Irene Ramos-Alvarez et al.American journal of physiology. Gastrointestinal and liver physiology, 315(2), G302-G317 (2018-04-20) Reversal of phosphate-induced ORAI1 expression, store-operated Ca2+ entry and osteogenic signaling by MgCl2 in human aortic smooth muscle cells.Xuexue Zhu et al.Biochemical and biophysical research communications, 523(1), 18-24 (2019-12-14) Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK.Mengqi Li et al.Cell metabolism, 30(3), 508-524 (2019-06-18) Rikkunshito Depolarizes Pacemaker Potentials of Cultured Interstitial Cells of Cajal through Ghrelin Receptors in Murine Small Intestine.Jeong Nam Kim et al.Digestion, 101(3), 227-238 (2019-03-20) GL261 glioma tumor cells respond to ATP with an intracellular calcium rise and glutamate release.Averey D Strong et al.Molecular and cellular biochemistry, 446(1-2), 53-62 (2018-01-11) Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury: Involvement of PARK2-dependent mitophagy.Xiangnan Zhang et al.Autophagy, 10(10), 1801-1813 (2014-08-16) Liver parenchymal cells lacking Lipocalin 2 (LCN2) are prone to endoplasmic reticulum stress and unfolded protein response.Erawan Borkham-Kamphorst et al.Cellular signalling, 55, 90-99 (2019-01-08) TLR7 (Toll-Like Receptor 7) Facilitates Heme Scavenging Through the BTK (Bruton Tyrosine Kinase)-CRT (Calreticulin)-LRP1 (Low-Density Lipoprotein Receptor-Related Protein-1)-Hx (Hemopexin) Pathway in Murine Intracerebral Hemorrhage.Gaiqing Wang et al.Stroke, 49(12), 3020-3029 (2018-12-21) Loss of tumor susceptibility gene 101 (TSG101) perturbs endoplasmic reticulum structure and function.Zenia Kaul et al.Biochimica et biophysica acta. Molecular cell research, 1867(9), 118741-118741 (2020-05-19) Polarized E-cadherin endocytosis directs actomyosin remodeling during embryonic wound repair.Miranda V Hunter et al.The Journal of cell biology, 210(5), 801-816 (2015-08-26) Sirtuin-1 ameliorates cadmium-induced endoplasmic reticulum stress and pyroptosis through XBP-1s deacetylation in human renal tubular epithelial cells.Xin Chou et al.Archives of toxicology, 93(4), 965-986 (2019-02-24) Novel Protein Kinase C-Mediated Control of Orai1 Function in Invasive Melanoma.Robert Hooper et al.Molecular and cellular biology, 35(16), 2790-2798 (2015-06-10) Lack of GCN5 remarkably enhances the resistance against prolonged endoplasmic reticulum stress-induced apoptosis through up-regulation of Bcl-2 gene expression.Hidehiko Kikuchi et al.Biochemical and biophysical research communications, 463(4), 870-875 (2015-06-19) Autophagy is involved in ethanol-induced cardia bifida during chick cardiogenesis.Shuai Li et al.Cell cycle (Georgetown, Tex.), 14(20), 3306-3317 (2015-09-01) Angiotensin-converting enzyme 2 inhibits endoplasmic reticulum stress-associated pathway to preserve nonalcoholic fatty liver disease.Xi Cao et al.Diabetes/metabolism research and reviews, 35(4), e3123-e3123 (2019-01-04) Identification of the cellular mechanisms that modulate trafficking of frizzled family receptor 4 (FZD4) missense mutants associated with familial exudative vitreoretinopathy.Reham M Milhem et al.Investigative ophthalmology & visual science, 55(6), 3423-3431 (2014-04-20) Low-level laser irradiation modulates brain-derived neurotrophic factor mRNA transcription through calcium-dependent activation of the ERK/CREB pathway.Xiaodong Yan et al.Lasers in medical science, 32(1), 169-180 (2016-11-20) Tanshinone IIA Facilitates TRAIL Sensitization by Up-regulating DR5 through the ROS-JNK-CHOP Signaling Axis in Human Ovarian Carcinoma Cell Lines.Chia-Che Chang et al.Chemical research in toxicology, 28(8), 1574-1583 (2015-07-24) Differential requirements for H/ACA ribonucleoprotein components in cell proliferation and response to DNA damage.Ping Lin et al.Histochemistry and cell biology, 144(6), 543-558 (2015-08-13) The heparanase inhibitor PG545 is a potent anti-lymphoma drug: Mode of action.Marina Weissmann et al.Matrix biology : journal of the International Society for Matrix Biology, 77, 58-72 (2018-08-11) Localization of BCR-ABL to Stress Granules Contributes to Its Oncogenic Function.Sayaka Kashiwagi et al.Cell structure and function, 44(2), 195-204 (2019-11-19) Loss of MCU prevents mitochondrial fusion in G1-S phase and blocks cell cycle progression and proliferation.Olha M Koval et al.Science signaling, 12(579) (2019-05-02) The androgen-induced protein AIbZIP facilitates proliferation of prostate cancer cells through downregulation of p21 expression.Xiang Cui et al.Scientific reports, 6, 37310-37310 (2016-11-18) Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress.Andrea D'Osualdo et al.PloS one, 10(6), e0130635-e0130635 (2015-06-19) Inhibition of cAMP-Dependent PKA Activates β2-Adrenergic Receptor Stimulation of Cytosolic Phospholipase A2 via Raf-1/MEK/ERK and IP3-Dependent Ca2+ Signaling in Atrial Myocytes.M R Pabbidi et al.PloS one, 11(12), e0168505-e0168505 (2016-12-16) The Stress Granule Transcriptome Reveals Principles of mRNA Accumulation in Stress Granules.Anthony Khong et al.Molecular cell, 68(4), 808-820 (2017-11-14) Translational control of a human CDKN1A mRNA splice variant regulates the fate of UVB-irradiated human keratinocytes.Ann E Collier et al.Molecular biology of the cell, 29(1), 29-41 (2017-11-10) Purine nucleoside phosphorylase inhibition ameliorates age-associated lower urinary tract dysfunctions.Lori A Birder et al.JCI insight, 5(20) (2020-09-11) The cell-wide web coordinates cellular processes by directing site-specific Ca2+ flux across cytoplasmic nanocourses.Jingxian Duan et al.Nature communications, 10(1), 2299-2299 (2019-05-28) Glutamate-induced rapid induction of Arc/Arg3.1 requires NMDA receptor-mediated phosphorylation of ERK and CREB.Tao Chen et al.Neuroscience letters, 661, 23-28 (2017-09-19) TMCO1 is essential for ovarian follicle development by regulating ER Ca2+ store of granulosa cells.Zhongshuai Sun et al.Cell death and differentiation, 25(9), 1686-1701 (2018-02-23) Induction of ER Stress by an AAV5 BDD FVIII Construct Is Dependent on the Strength of the Hepatic-Specific Promoter.Sylvia Fong et al.Molecular therapy. Methods & clinical development, 18, 620-630 (2020-08-11) Epstein-barr virus blocks the autophagic flux and appropriates the autophagic machinery to enhance viral replication.Marisa Granato et al.Journal of virology, 88(21), 12715-12726 (2014-08-22) Ca2+ mediates axotomy-induced necrosis and apoptosis of satellite glial cells remote from the transection site in the isolated crayfish mechanoreceptor.Andrey Khaitin et al.Molecular and cellular neurosciences, 88, 7-15 (2017-12-12) Transient Ca2+ depletion from the endoplasmic reticulum is critical for skeletal myoblast differentiation.Keiko Nakanishi et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(5), 2137-2149 (2015-02-14) Water-mediated interactions influence the binding of thapsigargin to sarco/endoplasmic reticulum calcium adenosinetriphosphatase.Eleonora S Paulsen et al.Journal of medicinal chemistry, 56(9), 3609-3619 (2013-04-12) Endoplasmic reticulum stress disrupts lysosomal homeostasis and induces blockade of autophagic flux in human trophoblasts.Akitoshi Nakashima et al.Scientific reports, 9(1), 11466-11466 (2019-08-09) Pharmacological inhibition of focal segmental glomerulosclerosis-related, gain of function mutants of TRPC6 channels by semi-synthetic derivatives of larixol.Nicole Urban et al.British journal of pharmacology, 174(22), 4099-4122 (2017-08-12) Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice.Kook Hwan Kim et al.Scientific reports, 8(1), 6789-6789 (2018-05-03) Astrocyte calcium waves propagate proximally by gap junction and distally by extracellular diffusion of ATP released from volume-regulated anion channels.Yuki Fujii et al.Scientific reports, 7(1), 13115-13115 (2017-10-17) The role of endoplasmic reticulum stress in hippocampal insulin resistance.Catrina Sims-Robinson et al.Experimental neurology, 277, 261-267 (2016-01-18) Adaptive endoplasmic reticulum stress signalling via IRE1α-XBP1 preserves self-renewal of haematopoietic and pre-leukaemic stem cells.Lu Liu et al.Nature cell biology, 21(3), 328-337 (2019-02-20) The integrated stress response induces R-loops and hinders replication fork progression.Josephine Ann Mun Yee Choo et al.Cell death & disease, 11(7), 538-538 (2020-07-18) ER stress activation impairs the expression of circadian clock and clock-controlled genes in NIH3T3 cells via an ATF4-dependent mechanism.Lei Gao et al.Cellular signalling, 57, 89-101 (2019-02-01) ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6α-Endoplasmic Reticulum Stress-Beclin1 Autophagy Regulatory Pathway.Jie Dang et al.Journal of immunology (Baltimore, Md. : 1950), 199(5), 1647-1659 (2017-07-28) Thapsigargin inhibits a potassium conductance and stimulates calcium influx in the intact rat lens.G R Thomas et al.The Journal of physiology, 516 ( Pt 1), 191-199 (1999-03-06) Expression and release of glucose-regulated protein-78 (GRP78) in multiple myeloma.Normann Steiner et al.Oncotarget, 8(34), 56243-56254 (2017-09-17) Role of subcellular calcium redistribution in regulating apoptosis and autophagy in cadmium-exposed primary rat proximal tubular cells.Fei Liu et al.Journal of inorganic biochemistry, 164, 99-109 (2016-09-26) Hyperthermia and associated changes in membrane fluidity potentiate P2X7 activation to promote tumor cell death.Paola de Andrade Mello et al.Oncotarget, 8(40), 67254-67268 (2017-10-06) Biopsy-derived Intestinal Epithelial Cell Cultures for Pathway-based Stratification of Patients With Inflammatory Bowel Disease.Wiebe Vanhove et al.Journal of Crohn's & colitis, 12(2), 178-187 (2017-10-14) Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells.Dominique Thuringer et al.Oncotarget, 6(12), 10267-10283 (2015-04-15) Fission Yeast Puf2, a Pumilio and FBF Family RNA-Binding Protein, Links Stress Granules to Processing Bodies.Wan-Yi Hsiao et al.Molecular and cellular biology, 40(9) (2020-02-20) A sensitive assay for the biosynthesis and secretion of MANF using NanoLuc activity.Junpei Norisada et al.Biochemical and biophysical research communications, 449(4), 483-489 (2014-05-23) Galectin-3 modulates epithelial cell adaptation to stress at the ER-mitochondria interface.Lucie Coppin et al.Cell death & disease, 11(5), 360-360 (2020-05-14) Depolarizing Effects of Daikenchuto on Interstitial Cells of Cajal from Mouse Small Intestine.Hyungwoo Kim et al.Pharmacognosy magazine, 13(49), 141-147 (2017-02-22) AMP-activated kinase is a regulator of fibroblast growth factor 23 production.Philipp Glosse et al.Kidney international, 94(3), 491-501 (2018-06-05) Improvement of immunodetection of the transcription factor C/EBP homologous protein by western blot.Jonathan Turpin et al.Analytical biochemistry, 601, 113775-113775 (2020-05-18) The early signaling pathway of live yeast cell derivative in THP-1 monocytes.Eric I Gruenstein et al.Cell calcium, 73, 112-120 (2018-05-08) Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT.Stephanie Dabo et al.Scientific reports, 7(1), 16129-16129 (2017-11-25) Supra-pharmacological concentration of capsaicin stimulates brown adipogenesis through induction of endoplasmic reticulum stress.Ryosuke Kida et al.Scientific reports, 8(1), 845-845 (2018-01-18) Suppression effects of O-demethyldemethoxycurcumin on thapsigargin triggered on endoplasmic reticulum stress in SK-N-SH cells.Adchara Janyou et al.Neurotoxicology, 50, 92-100 (2015-08-13) Familial Alzheimer's disease-linked presenilin mutants and intracellular Ca2+ handling: A single-organelle, FRET-based analysis.Elisa Greotti et al.Cell calcium, 79, 44-56 (2019-03-02) Differential 12-O-Tetradecanoylphorbol-13-acetate-induced activation of rat mammary carcinoma susceptibility Fbxo10 variant promoters via a PKC-AP1 pathway.Xin Xu et al.Molecular carcinogenesis, 54(2), 134-147 (2013-09-07) Thapsigargin induces apoptosis of prostate cancer through cofilin-1 and paxillin.Fengyu Huang et al.Oncology letters, 16(2), 1975-1980 (2018-07-17) Resveratrol is not compatible with a Fura-2-based assay for measuring intracellular Ca²⁺ signaling.Ram Chandra Paudel et al.Biochemical and biophysical research communications, 450(4), 1626-1630 (2014-07-19) MICU1 Confers Protection from MCU-Dependent Manganese Toxicity.Jennifer Wettmarshausen et al.Cell reports, 25(6), 1425-1435 (2018-11-08) A Potential Role for Endoplasmic Reticulum Stress in Progesterone Deficiency in Obese Women.Nozomi Takahashi et al.Endocrinology, 158(1), 84-97 (2016-11-26) Functional coupling between BKCa and SOC channels.Taiding Wu et al.Tissue & cell, 66, 101394-101394 (2020-09-17) Transcription regulator TRIP-Br2 mediates ER stress-induced brown adipocytes dysfunction.Guifen Qiang et al.Scientific reports, 7, 40215-40215 (2017-01-10) Ca2+ -independent and voltage-dependent exocytosis in mouse chromaffin cells.José Moya-Díaz et al.Acta physiologica (Oxford, England), 228(4), e13417-e13417 (2019-11-27) OS-9 facilitates turnover of nonnative GRP94 marked by hyperglycosylation.Devin Dersh et al.Molecular biology of the cell, 25(15), 2220-2234 (2014-06-06) Effects ofSang Weon Lee et al.Experimental and therapeutic medicine, 13(1), 327-334 (2017-01-27) Functional cytochrome P450 1A enzymes are induced in mouse and human islets following pollutant exposure.Muna Ibrahim et al.Diabetologia, 63(1), 162-178 (2019-11-30) P2X1 Receptor Antagonists Inhibit HIV-1 Fusion by Blocking Virus-Coreceptor Interactions.Charline Giroud et al.Journal of virology, 89(18), 9368-9382 (2015-07-03) Intestinal epithelial potassium channels and CFTR chloride channels activated in ErbB tyrosine kinase inhibitor diarrhea.Tianying Duan et al.JCI insight, 4(4) (2019-01-23) Cigarette Smoke Extract Promotes Human Lung Myofibroblast Differentiation by the Induction of Endoplasmic Reticulum Stress.Min Song et al.Respiration; international review of thoracic diseases, 98(4), 347-356 (2019-08-16) By reducing global mRNA translation in several ways, 2-deoxyglucose lowers MCL-1 protein and sensitizes hemopoietic tumor cells to BH3 mimetic ABT737.Maximilien Tailler et al.Cell death and differentiation, 26(9), 1766-1781 (2018-12-13) Exercise Affects T-Cell Function by Modifying Intracellular Calcium Homeostasis.Renyi Liu et al.Medicine and science in sports and exercise, 49(1), 29-39 (2016-08-16) Obesity induces preadipocyte CD36 expression promoting inflammation via the disruption of lysosomal calcium homeostasis and lysosome function.Xiaoxiao Luo et al.EBioMedicine, 56, 102797-102797 (2020-06-10) PI 3-kinase- and ERK-MAPK-dependent mechanisms underlie Glucagon-Like Peptide-1-mediated activation of Sprague Dawley colonic myenteric neurons.Rebecca O'Brien et al.Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 31(8), e13631-e13631 (2019-05-24) A pupal transcriptomic screen identifies Ral as a target of store-operated calcium entry in Drosophila neurons.Shlesha Richhariya et al.Scientific reports, 7, 42586-42586 (2017-02-15) ER Stress Induces Cell Cycle Arrest at the G2/M Phase Through eIF2α Phosphorylation and GADD45α.Duckgue Lee et al.International journal of molecular sciences, 20(24) (2019-12-19) IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions.Kohsuke Kanekura et al.Science signaling, 8(382), ra62-ra62 (2015-06-25) TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway.Yanfeng Liu et al.Nature communications, 11(1), 348-348 (2020-01-19) EPO and TMBIM3/GRINA Promote the Activation of the Adaptive Arm and Counteract the Terminal Arm of the Unfolded Protein Response after Murine Transient Cerebral Ischemia.Pardes Habib et al.International journal of molecular sciences, 20(21) (2019-11-07) Involvement of endoplasmic reticulum stress in all-trans-retinal-induced retinal pigment epithelium degeneration.Jie Li et al.Toxicological sciences : an official journal of the Society of Toxicology, 143(1), 196-208 (2014-10-22) Small molecule regulators of autophagy identified by an image-based high-throughput screen.Lihong Zhang et al.Proceedings of the National Academy of Sciences of the United States of America, 104(48), 19023-19028 (2007-11-21) Design, synthesis, and development of novel guaianolide-endoperoxides as potential antimalarial agents.Lingzhi Sun et al.Journal of medicinal chemistry, 53(21), 7864-7868 (2010-10-16) Fatostatin induces pro- and anti-apoptotic lipid accumulation in breast cancer.Viktor Brovkovych et al.Oncogenesis, 7(8), 66-66 (2018-08-25) A STIM1-dependent 'trafficking trap' mechanism regulates Orai1 plasma membrane residence and Ca²⁺ influx levels.Rawad Hodeify et al.Journal of cell science, 128(16), 3143-3154 (2015-06-28) STIM1 Phosphorylation at Y361 Recruits Orai1 to STIM1 Puncta and Induces CaPascal Yazbeck et al.Scientific reports, 7, 42758-42758 (2017-02-22) Increased production of interleukin-17 over interleukin-10 by treg cells implicates inducible costimulator molecule in experimental spondyloarthritis.Luiza M Araujo et al.Arthritis & rheumatology (Hoboken, N.J.), 66(9), 2412-2422 (2014-06-10) The repair and autophagy mechanisms of hypoxia-regulated bFGF-modified primary embryonic neural stem cells in spinal cord injury.Sipin Zhu et al.Stem cells translational medicine, 9(5), 603-619 (2020-02-07) Mutations in RHOT1 Disrupt Endoplasmic Reticulum-Mitochondria Contact Sites Interfering with Calcium Homeostasis and Mitochondrial Dynamics in Parkinson's Disease.Dajana Grossmann et al.Antioxidants & redox signaling, 31(16), 1213-1234 (2019-07-16) Comparison of the pharmacologic profiles of arginine vasopressin and oxytocin analogs at marmoset, titi monkey, macaque, and human oxytocin receptors.Marsha L Pierce et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 125, 109832-109832 (2020-02-06) Unconventional secretion factor GRASP55 is increased by pharmacological unfolded protein response inducers in neurons.Anna Maria van Ziel et al.Scientific reports, 9(1), 1567-1567 (2019-02-09) Maresin 1, a specialized proresolving mediator, stimulates intracellular [Ca2+ ] and secretion in conjunctival goblet cells.Markus V Olsen et al.Journal of cellular physiology, 236(1), 340-353 (2020-06-09) Protective effect of mild endoplasmic reticulum stress on radiation-induced bystander effects in hepatocyte cells.Yuexia Xie et al.Scientific reports, 6, 38832-38832 (2016-12-14) Rapid effects of aldosterone in primary cultures of cardiomyocytes - do they suggest the existence of a membrane-bound receptor?Carolina Morais Araujo et al.Journal of receptor and signal transduction research, 36(5), 435-444 (2016-06-17) Anti-Inflammatory Activity of Kurarinone Involves Induction of HO-1 via the KEAP1/Nrf2 Pathway.Sakiko Nishikawa et al.Antioxidants (Basel, Switzerland), 9(9) (2020-09-13) β-arrestin-2 enhances intestinal epithelial apoptosis in necrotizing enterocolitis.Dong Fu et al.Aging, 11(19), 8294-8312 (2019-10-16) Uncovering a Dual Regulatory Role for Caspases During Endoplasmic Reticulum Stress-induced Cell Death.Veronica G Anania et al.Molecular & cellular proteomics : MCP, 15(7), 2293-2307 (2016-04-30) Upregulation of Orai1 and increased calcium entry contribute to angiotensin II-induced human coronary smooth muscle cell proliferation: Running Title: Angiotensin II-induced human coronary smooth muscle cells proliferation.Bei Liu et al.Peptides, 133, 170386-170386 (2020-08-23) Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias.Laura Hinze et al.Cancer cell, 35(4), 664-676 (2019-04-17) Porcine reproductive and respiratory syndrome virus infection induces endoplasmic reticulum stress, facilitates virus replication, and contributes to autophagy and apoptosis.Quangang Chen et al.Scientific reports, 10(1), 13131-13131 (2020-08-06) The flavonoid ampelopsin inhibited cell growth and induced apoptosis and G0/G1 arrest in human osteosarcoma MG-63 cells in vitro.Meng Lu et al.Die Pharmazie, 70(6), 388-393 (2015-07-21) Pyruvate kinase M1 interacts with A-Raf and inhibits endoplasmic reticulum stress-induced apoptosis by activating MEK1/ERK pathway in mouse insulinoma cells.Yuta Horiuchi et al.Cellular signalling, 38, 212-222 (2017-07-27) Structural modification of trilobolide for upgrading its immunobiological properties and reducing its cytotoxic action.Juraj Harmatha et al.Fitoterapia, 134, 88-95 (2019-02-08) An immortalized steroidogenic goat granulosa cell line as a model system to study the effect of the endoplasmic reticulum (ER)-stress response on steroidogenesis.Diqi Yang et al.The Journal of reproduction and development, 63(1), 27-36 (2016-10-18) Tunicamycin specifically aggravates ER stress and overcomes chemoresistance in multidrug-resistant gastric cancer cells by inhibiting N-glycosylation.Jian Wu et al.Journal of experimental & clinical cancer research : CR, 37(1), 272-272 (2018-11-11) KSHV activates unfolded protein response sensors but suppresses downstream transcriptional responses to support lytic replication.Benjamin P Johnston et al.PLoS pathogens, 15(12), e1008185-e1008185 (2019-12-04) Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver.Vanessa Dubois et al.Molecular systems biology, 16(5), e9156-e9156 (2020-05-15) Glucosamine induces ER stress by disrupting lipid-linked oligosaccharide biosynthesis and N-linked protein glycosylation.Daniel R Beriault et al.American journal of physiology. Endocrinology and metabolism, 312(1), E48-E57 (2016-11-24) Acetylcholine induces Ca2+ signaling in chicken retinal pigmented epithelial cells during dedifferentiation.Mariko Sekiguchi-Tonosaki et al.American journal of physiology. Cell physiology, 296(5), C1195-C1206 (2009-02-27) Multiple Sources of Ca2+ Contribute to Methylmercury-Induced Increased Frequency of Spontaneous Inhibitory Synaptic Responses in Cerebellar Slices of Rat.Yukun Yuan et al.Toxicological sciences : an official journal of the Society of Toxicology, 150(1), 117-130 (2016-01-07) Purinergic Receptor Transactivation by theWayne Stallaert et al.Molecular pharmacology, 91(5), 533-544 (2017-03-11) Golgi stress-induced transcriptional changes mediated by MAPK signaling and three ETS transcription factors regulate MCL1 splicing.Jan Baumann et al.Molecular biology of the cell, 29(1), 42-52 (2017-11-10) Production of BBF2H7-derived small peptide fragments via endoplasmic reticulum stress-dependent regulated intramembrane proteolysis.Koji Matsuhisa et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(1), 865-880 (2020-01-10) RAC1-Dependent ORAI1 Translocation to the Leading Edge Supports Lamellipodia Formation and Directional Persistence.Aida M Lopez-Guerrero et al.Scientific reports, 10(1), 6580-6580 (2020-04-22) Ubiquitin ligase LRSAM1 suppresses neurodegenerative diseases linked aberrant proteins induced cell death.Ribhav Mishra et al.The international journal of biochemistry & cell biology, 120, 105697-105697 (2020-01-27) Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes.Arvin Iracheta-Vellve et al.The Journal of biological chemistry, 291(52), 26794-26805 (2016-11-05) Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity.Masaya Oshima et al.Diabetologia, 63(2), 395-409 (2019-12-05) TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis.Prashant B Shambharkar et al.PloS one, 10(5), e0127480-e0127480 (2015-05-23) Contribution of Cav1.2 Ca2+ channels and store-operated Ca2+ entry to pig urethral smooth muscle contraction.Benjamin E Rembetski et al.American journal of physiology. Renal physiology, 318(2), F496-F505 (2020-01-07) Is lymphocyte adenosine a diagnostic marker of clinical malignant hyperthermia? A pilot study.Saiid Bina et al.Critical care medicine, 43(3), 584-593 (2014-12-06) Oscillatory stimuli differentiate adapting circuit topologies.Sahand Jamal Rahi et al.Nature methods, 14(10), 1010-1016 (2017-08-29) Extracellular acidosis selectively inhibits pharmacomechanical coupling induced by carbachol in strips of rat gastric fundus.Daniel Maia Nogueira de Oliveira et al.Experimental physiology, 102(12), 1607-1618 (2017-09-21) Fumarate hydratase-deficient renal cell carcinoma cells respond to asparagine by activation of the unfolded protein response and stimulation of the hexosamine biosynthetic pathway.Rony Panarsky et al.Cancer & metabolism, 8, 7-7 (2020-08-11) Beta-Glycerophosphate-Induced ORAI1 Expression and Store Operated Ca2+ Entry in Megakaryocytes.Lisann Pelzl et al.Scientific reports, 10(1), 1728-1728 (2020-02-06) Protein synthesis inhibition and GADD34 control IFN-β heterogeneous expression in response to dsRNA.Alexandre Dalet et al.The EMBO journal, 36(6), 761-782 (2017-01-20) Store-operated Ca2+ Entry-associated Regulatory factor (SARAF) Plays an Important Role in the Regulation of Arachidonate-regulated Ca2+ (ARC) Channels.Letizia Albarran et al.The Journal of biological chemistry, 291(13), 6982-6988 (2016-01-29) Derinat Protects Skin against Ultraviolet-B (UVB)-Induced Cellular Damage.Wen-Li Hsu et al.Molecules (Basel, Switzerland), 20(11), 20297-20311 (2015-11-17) Hydrogen peroxide attenuates refilling of intracellular calcium store in mouse pancreatic acinar cells.Mi Na Yoon et al.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 21(2), 233-239 (2017-03-11) CReP mediates selective translation initiation at the endoplasmic reticulum.Jonathan P Kastan et al.Science advances, 6(23), eaba0745-eaba0745 (2020-06-17) GLP-1 Improves Adipocyte Insulin Sensitivity Following Induction of Endoplasmic Reticulum Stress.Yaojing Jiang et al.Frontiers in pharmacology, 9, 1168-1168 (2018-11-22) N-Acetylcysteine increases corneal endothelial cell survival in a mouse model of Fuchs endothelial corneal dystrophy.Eun Chul Kim et al.Experimental eye research, 127, 20-25 (2014-06-22) Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5-/- mice.Yan Li et al.Nature communications, 10(1), 1492-1492 (2019-04-04) HIV Protease Inhibitors Sensitize Human Head and Neck Squamous Carcinoma Cells to Radiation by Activating Endoplasmic Reticulum Stress.Runping Liu et al.PloS one, 10(5), e0125928-e0125928 (2015-05-02) Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents.Chen Lossos et al.Cancer discovery, 9(7), 944-961 (2019-05-02) DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.Pengli Zheng et al.Cell research, 28(8), 833-854 (2018-07-22) The Pyrazole Derivative BTP2 Attenuates IgG Immune Complex-induced Inflammation.Georgios Sogkas et al.Inflammation, 41(1), 42-49 (2017-08-31) Mouse strain-dependent egg factors regulate calcium signals at fertilization.Caitlin E McDonough et al.Molecular reproduction and development, 87(2), 284-292 (2020-01-17) Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3.Justin K Murray et al.Journal of medicinal chemistry, 58(17), 6784-6802 (2015-08-20) Activation of odorant receptor in colorectal cancer cells leads to inhibition of cell proliferation and apoptosis.Lea Weber et al.PloS one, 12(3), e0172491-e0172491 (2017-03-09) The endocannabinoid 2-arachidonoylglycerol promotes endoplasmic reticulum stress in placental cells.Marta Almada et al.Reproduction (Cambridge, England), 160(2), 171-180 (2020-05-02) Frequency-specific effects of repetitive magnetic stimulation on primary astrocyte cultures.Darren Clarke et al.Restorative neurology and neuroscience, 35(6), 557-569 (2017-11-25) Enhanced ANGPTL2 expression in adipose tissues and its association with insulin resistance in obese women.Jimin Kim et al.Scientific reports, 8(1), 13976-13976 (2018-09-20) Adenosine Receptor Agonists Increase the Inhibition of Platelet Function by P2Y12 Antagonists in a cAMP- and Calcium-Dependent Manner.Nina Wolska et al.Pharmaceuticals (Basel, Switzerland), 13(8) (2020-08-06) Role of Ca2+ transients at the node of the mouse embryo in breaking of left-right symmetry.Katsutoshi Mizuno et al.Science advances, 6(30), eaba1195-eaba1195 (2020-08-04) Increased expression of endoplasmic reticulum stress and unfolded protein response genes in peripheral blood mononuclear cells from patients with limited cutaneous systemic sclerosis and pulmonary arterial hypertension.Stefania Lenna et al.Arthritis and rheumatism, 65(5), 1357-1366 (2013-02-13) Niche-specific gene expression in a parasitic nematode; increased expression of immunomodulators in Teladorsagia circumcincta larvae derived from host mucosa.Tom N McNeilly et al.Scientific reports, 7(1), 7214-7214 (2017-08-05) Trpml controls actomyosin contractility and couples migration to phagocytosis in fly macrophages.Sandra Sofía Edwards-Jorquera et al.The Journal of cell biology, 219(3) (2020-01-16) Sodium entry through endothelial store-operated calcium entry channels: regulation by Orai1.Ningyong Xu et al.American journal of physiology. Cell physiology, 308(4), C277-C288 (2014-11-28) The GPR120 Agonist TUG-891 Inhibits the Motility and Phagocytosis of Mouse Alveolar Macrophages.Xing-Li Su et al.BioMed research international, 2020, 1706168-1706168 (2020-03-10) Reshaping of the Dendritic Cell Chromatin Landscape and Interferon Pathways during HIV Infection.Jarrod S Johnson et al.Cell host & microbe, 23(3), 366-381 (2018-03-16) Novel role for TRPC4 in regulation of macroautophagy by a small molecule in vascular endothelial cells.Lu Zhang et al.Biochimica et biophysica acta, 1853(2), 377-387 (2014-12-06) The toxicity of multi-walled carbon nanotubes (MWCNTs) to human endothelial cells: The influence of diameters of MWCNTs.Xuqi Zhao et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 126, 169-177 (2019-02-26) Erythromycin relaxes BALB/c mouse airway smooth muscle.Yan Cai et al.Life sciences, 221, 135-142 (2019-02-08) Prostaglandin E1 protects hepatocytes against endoplasmic reticulum stress-induced apoptosis via protein kinase A-dependent induction of glucose-regulated protein 78 expression.Fang-Wan Yang et al.World journal of gastroenterology, 23(40), 7253-7264 (2017-11-17) Cellular stress amplifies TLR3/4-induced CXCL1/2 gene transcription in mononuclear phagocytes via RIPK1.Chenyang Zhao et al.Journal of immunology (Baltimore, Md. : 1950), 193(2), 879-888 (2014-06-13) Elucidation of the topography of the thapsigargin binding site in the sarco-endoplasmic calcium ATPase.Dorthe Mondrup Skytte et al.Bioorganic & medicinal chemistry, 18(15), 5634-5646 (2010-07-10) Lactobacillus acidophilus suppresses intestinal inflammation by inhibiting endoplasmic reticulum stress.Da Hye Kim et al.Journal of gastroenterology and hepatology, 34(1), 178-185 (2018-06-23) Effects of GSK2606414 on cell proliferation and endoplasmic reticulum stress‑associated gene expression in retinal pigment epithelial cells.Xintong Jiang et al.Molecular medicine reports, 15(5), 3105-3110 (2017-03-31) The HSV-1 mechanisms of cell-to-cell spread and fusion are critically dependent on host PTP1B.Jillian C Carmichael et al.PLoS pathogens, 14(5), e1007054-e1007054 (2018-05-10) Calreticulin regulates TGF-β1-induced epithelial mesenchymal transition through modulating Smad signaling and calcium signaling.Yanjiao Wu et al.The international journal of biochemistry & cell biology, 90, 103-113 (2017-08-06) Suppression of IgE-Independent Degranulation of Murine Connective Tissue-Type Mast Cells by Dexamethasone.Keiko Yamada et al.Cells, 8(2) (2019-02-06) Deletion of Tmtc4 activates the unfolded protein response and causes postnatal hearing loss.Jiang Li et al.The Journal of clinical investigation, 128(11), 5150-5162 (2018-09-07) Marked Sexual Dimorphism in the Role of the Ryanodine Receptor in a Model of Pain Chronification in the Rat.Luiz F Ferrari et al.Scientific reports, 6, 31221-31221 (2016-08-09) iCa2+ Flux, ROS and IL-10 Determines Cytotoxic, and Suppressor T Cell Functions in Chronic Human Viral Infections.Subhasmita Mohanty et al.Frontiers in immunology, 11, 83-83 (2020-03-27) Epigenetic loss of the endoplasmic reticulum-associated degradation inhibitor SVIP induces cancer cell metabolic reprogramming.Pere Llinàs-Arias et al.JCI insight, 5 (2019-03-08) Multiple Knockout of Classical HLA Class II β-Chains by CRISPR/Cas9 Genome Editing Driven by a Single Guide RNA.Pietro Crivello et al.Journal of immunology (Baltimore, Md. : 1950), 202(6), 1895-1903 (2019-02-01) Total synthesis of two novel subpicomolar sarco/endoplasmatic reticulum Ca2+-ATPase inhibitors designed by an analysis of the binding site of thapsigargin.Helmer Søhoel et al.Journal of medicinal chemistry, 48(22), 7005-7011 (2005-10-28) Perinatal supplementation of 4-phenylbutyrate and glutamine attenuates endoplasmic reticulum stress and improves colonic epithelial barrier function in rats born with intrauterine growth restriction.Axel Désir-Vigné et al.The Journal of nutritional biochemistry, 55, 104-112 (2018-02-08) Steroids from Helleborus caucasicus reduce cancer cell viability inducing apoptosis and GRP78 down-regulation.Stefania Martucciello et al.Chemico-biological interactions, 279, 43-50 (2017-11-12) Up-regulation of CDK9 kinase activity and Mcl-1 stability contributes to the acquired resistance to cyclin-dependent kinase inhibitors in leukemia.Yuh-Ying Yeh et al.Oncotarget, 6(5), 2667-2679 (2015-01-19) Ca2+ signalling plays a role in celastrol-mediated suppression of synovial fibroblasts of rheumatoid arthritis patients and experimental arthritis in rats.Vincent Kam Wai Wong et al.British journal of pharmacology, 176(16), 2922-2944 (2019-05-28) Gold Nanoshell-Mediated Remote Myotube Activation.Attilio Marino et al.ACS nano, 11(3), 2494-2508 (2017-01-21) Dicer and microRNAs protect adult dopamine neurons.Piotr Chmielarz et al.Cell death & disease, 8(5), e2813-e2813 (2017-05-26) Bmal1-deficient mouse fibroblast cells do not provide premature cellular senescence in vitro.Yasukazu Nakahata et al.Chronobiology international, 35(5), 730-738 (2018-01-27) Establishment and Characterization of a Murine Mucosal Mast Cell Culture Model.Aya Kakinoki et al.International journal of molecular sciences, 21(1) (2020-01-08) Astragalin augments basal calcium influx and insulin secretion in rat pancreatic islets.Diana Rey et al.Cell calcium, 80, 56-62 (2019-04-10) Differential Free Intracellular Calcium Release by Class II Antiarrhythmics in Cancer Cell Lines.Marta Reyes-Corral et al.The Journal of pharmacology and experimental therapeutics, 369(1), 152-162 (2019-01-19) Localized Calcium Signaling and the Control of Coupling at Cx36 Gap Junctions.Keith B Moore et al.eNeuro, 7(2) (2020-03-18) Thrombin mediates vagal apoptosis and dysfunction in inflammatory bowel disease.Danielle Fritze et al.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 18(8), 1495-1506 (2014-06-12) Punicalagin induces senescent growth arrest in human papillary thyroid carcinoma BCPAP cells via NF-κB signaling pathway.Xian Cheng et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 103, 490-498 (2018-04-21) Polyhexamethylene Guanidine Phosphate Damages Tight Junctions and the F-Actin Architecture by Activating Calpain-1 via the P2RX7/Ca2+ Signaling Pathway.Sun Woo Jin et al.Cells, 9(1) (2019-12-28) Deconvoluting Stress-Responsive Proteostasis Signaling Pathways for Pharmacologic Activation Using Targeted RNA Sequencing.Julia M D Grandjean et al.ACS chemical biology, 14(4), 784-795 (2019-03-02) Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila.Mary F Fontana et al.PLoS pathogens, 7(2), e1001289-e1001289 (2011-03-11) Palmitate enhanced the cytotoxicity of ZnO nanomaterials possibly by promoting endoplasmic reticulum stress.Jiamao Chen et al.Journal of applied toxicology : JAT, 39(5), 798-806 (2019-01-09) Endoplasmic reticulum stress-induced iRhom2 up-regulation promotes macrophage-regulated cardiac inflammation and lipid deposition in high fat diet (HFD)-challenged mice: Intervention of fisetin and metformin.Chen-Xu Ge et al.Free radical biology & medicine, 141, 67-83 (2019-06-04) Mangiferin suppresses endoplasmic reticulum stress in perivascular adipose tissue and prevents insulin resistance in the endothelium.Xiaoshan Xu et al.European journal of nutrition, 57(4), 1563-1575 (2017-03-30) Blockade of Interplay between IL-17A and Endoplasmic Reticulum Stress Attenuates LPS-Induced Lung Injury.So Ri Kim et al.Theranostics, 5(12), 1343-1362 (2015-10-31) TRPC6 Channels Are Required for Proliferation, Migration and Invasion of Breast Cancer Cell Lines by Modulation of Orai1 and Orai3 Surface Exposure.Isaac Jardin et al.Cancers, 10(9) (2018-09-19) Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries.Xiju He et al.Proceedings of the National Academy of Sciences of the United States of America, 114(23), E4582-E4591 (2017-05-21) Cellular effects of AP102, a somatostatin analog with balanced affinities for the hSSTR2 and hSSTR5 receptors.Jeremy Streuli et al.Neuropeptides, 68, 84-89 (2018-03-11) Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione.Douglas Matsunaga et al.PloS one, 11(10), e0165150-e0165150 (2016-10-27) Store depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer's disease.Timothy F Musial et al.Neurobiology of learning and memory, 154, 141-157 (2018-06-16) The role of de novo protein synthesis and SIRT1 in ER stress-induced Atf4 and Chop mRNA expression in mammalian cells.Stanley M H Chan et al.Biochimie, 138, 156-167 (2017-05-10) TMCO1-mediated Ca2+ leak underlies osteoblast functions via CaMKII signaling.Jianwei Li et al.Nature communications, 10(1), 1589-1589 (2019-04-10) Corticotropin-releasing hormone (CRH) stimulates cocaine- and amphetamine-regulated transcript gene (CART1) expression through CRH type 1 receptor (CRHR1) in chicken anterior pituitary.Chunheng Mo et al.Molecular and cellular endocrinology, 417, 166-177 (2015-09-13) Pacemaker function and neural responsiveness of subserosal interstitial cells of Cajal in the mouse colon.Bernard T Drumm et al.The Journal of physiology, 598(4), 651-681 (2019-12-08) Epigallocatechin Gallate Reduces Amyloid β-Induced Neurotoxicity via Inhibiting Endoplasmic Reticulum Stress-Mediated Apoptosis.Ke Du et al.Molecular nutrition & food research, 62(8), e1700890-e1700890 (2018-02-16) NDRG2 acts as a PERK co-factor to facilitate PERK branch and ERS-induced cell death.Mei Zhang et al.FEBS letters, 591(21), 3670-3681 (2017-09-28) Alpha-naphthoflavone induces apoptosis through endoplasmic reticulum stress via c-Src-, ROS-, MAPKs-, and arylhydrocarbon receptor-dependent pathways in HT22 hippocampal neuronal cells.Ah-Ran Yu et al.Neurotoxicology, 71, 39-51 (2018-12-07) Induction of endoplasmic reticulum stress under endotoxin tolerance increases inflammatory responses and decreases Pseudomonas aeruginosa pneumonia.Sena Kim et al.Journal of leukocyte biology, 104(5), 1003-1012 (2018-06-21) Role of the store-operated calcium entry protein, STIM1, in neutrophil chemotaxis and infiltration into a murine model of psoriasis-inflamed skin.Natacha Steinckwich et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(7), 3003-3013 (2015-04-04) Chemical chaperones reduce ionizing radiation-induced endoplasmic reticulum stress and cell death in IEC-6 cells.Eun Sang Lee et al.Biochemical and biophysical research communications, 450(2), 1005-1009 (2014-06-29) Novel HDAC inhibitor MAKV-8 and imatinib synergistically kill chronic myeloid leukemia cells via inhibition of BCR-ABL/MYC-signaling: effect on imatinib resistance and stem cells.Manon Lernoux et al.Clinical epigenetics, 12(1), 69-69 (2020-05-21) Sulforaphane Rescues Ethanol-Suppressed Angiogenesis through Oxidative and Endoplasmic Reticulum Stress in Chick Embryos.Guang Wang et al.Journal of agricultural and food chemistry, 66(36), 9522-9533 (2018-08-21) Calcium spikes, waves and oscillations in a large, patterned epithelial tissue.Ramya Balaji et al.Scientific reports, 7, 42786-42786 (2017-02-22) SERCaMP: a carboxy-terminal protein modification that enables monitoring of ER calcium homeostasis.Mark J Henderson et al.Molecular biology of the cell, 25(18), 2828-2839 (2014-07-18) SERCA2 dysfunction in Darier disease causes endoplasmic reticulum stress and impaired cell-to-cell adhesion strength: rescue by Miglustat.Magali Savignac et al.The Journal of investigative dermatology, 134(7), 1961-1970 (2014-01-07) Calcium regulation in aortic smooth muscle cells during the initial phase of tunicamycin-induced endo/sarcoplasmic reticulum stress.Gabriela Ziomek et al.European journal of pharmacology, 735, 86-96 (2014-04-29) Endoplasmic Reticulum Stress and Autophagy in Homocystinuria Patients with Remethylation Defects.Ainhoa Martínez-Pizarro et al.PloS one, 11(3), e0150357-e0150357 (2016-03-10) A novel specific PERK activator reduces toxicity and extends survival in Huntington's disease models.Javier Ganz et al.Scientific reports, 10(1), 6875-6875 (2020-04-25) A gene signal amplifier platform for monitoring the unfolded protein response.Carlos A Origel Marmolejo et al.Nature chemical biology, 16(5), 520-528 (2020-03-11) 4-Hydroperoxy-2-decenoic acid ethyl ester protects against 6-hydroxydopamine-induced cell death via activation of Nrf2-ARE and eIF2α-ATF4 pathways.Yuki Inoue et al.Neurochemistry international, 112, 288-296 (2017-08-22) Inhibition of Sphingosine Kinase 1 Ameliorates Angiotensin II-Induced Hypertension and Inhibits Transmembrane Calcium Entry via Store-Operated Calcium Channel.Parker C Wilson et al.Molecular endocrinology (Baltimore, Md.), 29(6), 896-908 (2015-04-15) ER stress in antigen-presenting cells promotes NKT cell activation through endogenous neutral lipids.Srinath Govindarajan et al.EMBO reports, 21(6), e48927-e48927 (2020-05-05) Activation of the Endoplasmic Reticulum Stress Response Impacts the NOD1 Signaling Pathway.Jonathan M Mendez et al.Infection and immunity, 87(8) (2019-05-22) The nerve growth factor alters calreticulin translocation from the endoplasmic reticulum to the cell surface and its signaling pathway in epithelial ovarian cancer cells.Carolina Andrea Vera et al.International journal of oncology, 50(4), 1261-1270 (2017-03-06) Improved skeletal muscle CaHiroaki Eshima et al.American journal of physiology. Regulatory, integrative and comparative physiology, 312(6), R1017-R1028 (2017-04-26) Apolipoprotein L9 interacts with LC3/GABARAP and is a microtubule-associated protein with a widespread subcellular distribution.Arvind A Thekkinghat et al.Biology open, 8(9) (2019-09-14) Molecular anatomy of the early events in STIM1 activation - oligomerization or conformational change?Marek K Korzeniowski et al.Journal of cell science, 130(17), 2821-2832 (2017-07-21) [6]-gingerol induces Ca2+ mobilization in Madin-Darby canine kidney cells.Chung-Yi Chen et al.Journal of natural products, 71(1), 137-140 (2008-01-10) Knock-in of Mutated hTAU Causes Insulin Resistance, Inflammation and Proteostasis Disturbance in a Mouse Model of Frontotemporal Dementia.Claire Hull et al.Molecular neurobiology, 57(1), 539-550 (2019-08-10) Neuroligin-2-derived peptide-covered polyamidoamine-based (PAMAM) dendrimers enhance pancreatic β-cells' proliferation and functions.Anna Munder et al.MedChemComm, 10(2), 280-293 (2019-03-19) Homocysteine causes vascular endothelial dysfunction by disrupting endoplasmic reticulum redox homeostasis.Xun Wu et al.Redox biology, 20, 46-59 (2018-10-08) Unfolded protein response regulates P53 expression in the pulmonary endothelium.Mohammad S Akhter et al.Journal of biochemical and molecular toxicology, 33(10), e22380-e22380 (2019-07-25) Poly-arginine-18 (R18) Confers Neuroprotection through Glutamate Receptor Modulation, Intracellular Calcium Reduction, and Preservation of Mitochondrial Function.Gabriella MacDougall et al.Molecules (Basel, Switzerland), 25(13) (2020-07-03) XBP1-s promotes colorectal cancer cell proliferation by inhibiting TAp73 transcriptional activity.Hong Ji et al.Biochemical and biophysical research communications, 508(1), 203-209 (2018-11-27) The inactivation domain of STIM1 acts through intramolecular binding to the coiled-coil domain in the resting state.Sang Kwon Lee et al.Journal of cell science, 133(1) (2019-12-14) Artemisinins inhibit Trypanosoma cruzi and Trypanosoma brucei rhodesiense in vitro growth.Yuliya V Mishina et al.Antimicrobial agents and chemotherapy, 51(5), 1852-1854 (2007-03-07) Hepatitis B virus upregulates host microRNAs that target apoptosis-regulatory genes in an in vitro cell model.Kirstine Overgaard Nielsen et al.Experimental cell research, 371(1), 92-103 (2018-07-31) Quinotrierixin inhibits proliferation of human retinal pigment epithelial cells.Chen Chen et al.Molecular vision, 19, 39-46 (2013-01-22) Cellular secretion and cytotoxicity of transthyretin mutant proteins underlie late-onset amyloidosis and neurodegeneration.Ridwan Babatunde Ibrahim et al.Cellular and molecular life sciences : CMLS, 77(7), 1421-1434 (2019-11-16) The "MYOCYTER" - Convert cellular and cardiac contractions into numbers with ImageJ.Tilman Grune et al.Scientific reports, 9(1), 15112-15112 (2019-10-24) Light-induced modulation of the mitochondrial respiratory chain activity: possibilities and limitations.Mariia Lunova et al.Cellular and molecular life sciences : CMLS, 77(14), 2815-2838 (2019-10-05) Cell-Based High-Throughput Luciferase Reporter Gene Assays for Identifying and Profiling Chemical Modulators of Endoplasmic Reticulum Signaling Protein, IRE1.Juan Rong et al.Journal of biomolecular screening, 20(10), 1232-1245 (2015-08-13) Selective inhibition of Ebola entry with selective estrogen receptor modulators by disrupting the endolysosomal calcium.Hanlu Fan et al.Scientific reports, 7, 41226-41226 (2017-01-25) Cyclosporine A binding to COX-2 reveals a novel signaling pathway that activates the IRE1α unfolded protein response sensor.Jody Groenendyk et al.Scientific reports, 8(1), 16678-16678 (2018-11-14) Distinct effects on cAMP signaling of carbamazepine and its structural derivatives do not correlate with their clinical efficacy in epilepsy.Sara Krarup et al.European journal of pharmacology, 886, 173413-173413 (2020-08-08) MITOL prevents ER stress-induced apoptosis by IRE1α ubiquitylation at ER-mitochondria contact sites.Keisuke Takeda et al.The EMBO journal, 38(15), e100999-e100999 (2019-08-02) The "MYOCYTER" - Convert cellular and cardiac contractions into numbers with ImageJ.Tilman Grune et al.Scientific reports, 9(1), 15112-15112 (2019-10-24) Caffeine-mediated BDNF release regulates long-term synaptic plasticity through activation of IRS2 signaling.Cristina Lao-Peregrín et al.Addiction biology, 22(6), 1706-1718 (2016-07-28) Calcium release from intracellular stores is involved in mitochondria depolarization after lowering extracellular pH in rat brain synaptosomes.Tatsiana G Dubouskaya et al.Acta neurobiologiae experimentalis, 78(4), 343-351 (2019-01-10) Regulation of the error-prone DNA polymerase Polκ by oncogenic signaling and its contribution to drug resistance.Kelsey Temprine et al.Science signaling, 13(629) (2020-04-30) The calcium ATPase SERCA2 regulates desmoplakin dynamics and intercellular adhesive strength through modulation of PKCα signaling.Ryan P Hobbs et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 25(3), 990-1001 (2010-12-16) A thiol probe for measuring unfolded protein load and proteostasis in cells.Moore Z Chen et al.Nature communications, 8(1), 474-474 (2017-09-09) Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease.Sandra I Mota et al.Biochimica et biophysica acta, 1852(7), 1428-1441 (2015-04-11) Urinary ERdj3 and mesencephalic astrocyte-derived neutrophic factor identify endoplasmic reticulum stress in glomerular disease.Nihad Tousson-Abouelazm et al.Laboratory investigation; a journal of technical methods and pathology, 100(7), 945-958 (2020-03-24) Semi-automatic Method for CaAmna E Abu Khamidakh et al.Annals of biomedical engineering, 44(11), 3408-3420 (2016-11-04) Fatty acid translocase promoted hepatitis B virus replication by upregulating the levels of hepatic cytosolic calcium.Jian Huang et al.Experimental cell research, 358(2), 360-368 (2017-07-13) CD5L is upregulated in hepatocellular carcinoma and promotes liver cancer cell proliferation and antiapoptotic responses by binding to HSPA5 (GRP78).Gemma Aran et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(7), 3878-3891 (2018-02-22) Zinc deficiency induced in Swiss 3T3 cells by a low-zinc medium impairs calcium entry and two mechanisms of entry are involved.Boyd L O'Dell et al.Biological trace element research, 152(1), 98-104 (2013-01-08) GPR120 Regulates Pancreatic Polypeptide Secretion From Male Mouse Islets via PLC-Mediated Calcium Mobilization.Yu-Feng Zhao et al.Endocrinology, 161(10) (2020-09-03) Calcium mobilization is both required and sufficient for initiating chromatin decondensation during activation of peripheral T-cells.Megan D Lee et al.Molecular immunology, 63(2), 540-549 (2014-12-03) Bile acids inhibit Na⁺/H⁺ exchanger and Cl⁻/HCO₃⁻ exchanger activities via cellular energy breakdown and Ca²⁺ overload in human colonic crypts.É Pallagi-Kunstár et al.Pflugers Archiv : European journal of physiology, 467(6), 1277-1290 (2014-07-13) Endoplasmic reticulum stress is transmissible in vitro between cells of the central nervous system.Neil T Sprenkle et al.Journal of neurochemistry, 148(4), 516-530 (2018-12-07) Autophagosomes cooperate in the degradation of intracellular C-terminal fragments of the amyloid precursor proteinAlexis E González et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31(6), 2446-2459 (2017-03-04) Inflammatory stress of pancreatic beta cells drives release of extracellular heat-shock protein 90α.Gail J Ocaña et al.Immunology, 151(2), 198-210 (2017-02-13) TFEB and TFE3 are novel components of the integrated stress response.José A Martina et al.The EMBO journal, 35(5), 479-495 (2016-01-28) Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells.Adrian E Morelli et al.Cell reports, 30(10), 3448-3465 (2020-03-12) Involvement of the Nrf2 pathway in the regulation of pterostilbene-induced apoptosis in HeLa cells via ER stress.Bo Zhang et al.Journal of pharmacological sciences, 126(3), 216-229 (2014-10-25) Orai3 channel is the 2-APB-induced endoplasmic reticulum calcium leak.Daniel Leon-Aparicio et al.Cell calcium, 65, 91-101 (2017-02-10) Magnetic Entropy as a Proposed Gating Mechanism for Magnetogenetic Ion Channels.Guillaume Duret et al.Biophysical journal, 116(3), 454-468 (2019-01-23) ZBTB7A, a miR-663a target gene, protects osteosarcoma from endoplasmic reticulum stress-induced apoptosis by suppressing LncRNA GAS5 expression.Lu Zhang et al.Cancer letters, 448, 105-116 (2019-02-13) Astringency is a trigeminal sensation that involves the activation of G protein-coupled signaling by phenolic compounds.Nicole Schöbel et al.Chemical senses, 39(6), 471-487 (2014-04-11) CaChong Ding et al.Journal of molecular histology, 49(1), 99-110 (2017-12-16) Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids.Manuele Piccolis et al.Molecular cell, 74(1), 32-44 (2019-03-09) Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response.Maria Valeria Giuli et al.Oncogenesis, 9(10), 93-93 (2020-10-20) Activation of the EIF2α/ATF4 and ATF6 Pathways in DU-145 Cells by Boric Acid at the Concentration Reported in Men at the US Mean Boron Intake.Sarah E Kobylewski et al.Biological trace element research, 176(2), 278-293 (2016-09-03) Metformin induces TPC-1 cell apoptosis through endoplasmic reticulum stress-associated pathways in vitro and in vivo.Jianwen Ye et al.International journal of oncology, 55(1), 331-339 (2019-06-11) Autophagosome-lysosome fusion is independent of V-ATPase-mediated acidification.Caroline Mauvezin et al.Nature communications, 6, 7007-7007 (2015-05-12) Effects of endoplasmic reticulum stress on apoptosis induction in radioresistant macrophages.Hironori Yoshino et al.Molecular medicine reports, 15(5), 2867-2872 (2017-04-28) Novel metabolic role for BDNF in pancreatic β-cell insulin secretion.Gianluca Fulgenzi et al.Nature communications, 11(1), 1950-1950 (2020-04-25) NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity.Jiahong Lu et al.Nature communications, 5, 3920-3920 (2014-05-23) Cyclic AMP inhibits neuromuscular junction maturation mediated by intracellular Ca2+.Wei Song et al.Neuroscience letters, 589, 104-109 (2015-01-18) Saturated fatty acid palmitate negatively regulates autophagy by promoting ATG5 protein degradation in meniscus cells.Aritra Mallik et al.Biochemical and biophysical research communications, 502(3), 370-374 (2018-06-01) Wolfram syndrome 1 gene regulates pathways maintaining beta-cell health and survival.Damien Abreu et al.Laboratory investigation; a journal of technical methods and pathology, 100(6), 849-862 (2020-02-16) TFEB-mediated increase in peripheral lysosomes regulates store-operated calcium entry.Luigi Sbano et al.Scientific reports, 7, 40797-40797 (2017-01-14) KChia-Yi Huang et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 37(17), 4433-4449 (2017-03-23) Cadmium-induced cytotoxicity in mouse liver cells is associated with the disruption of autophagic flux via inhibiting the fusion of autophagosomes and lysosomes.Hui Zou et al.Toxicology letters, 321, 32-43 (2019-12-22) Expression of a long variant of CRACR2A that belongs to the Rab GTPase protein family in endothelial cells.Lesley A Wilson et al.Biochemical and biophysical research communications, 456(1), 398-402 (2014-12-06) Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma.Duo Xu et al.British journal of cancer, 119(1), 65-75 (2018-06-21) Angiogenin Mediates Cell-Autonomous Translational Control under Endoplasmic Reticulum Stress and Attenuates Kidney Injury.Iadh Mami et al.Journal of the American Society of Nephrology : JASN, 27(3), 863-876 (2015-07-22) SUL-109 Protects Hematopoietic Stem Cells from Apoptosis Induced by Short-Term Hypothermic Preservation and Maintains Their Engraftment Potential.Fatima S F Aerts-Kaya et al.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 26(4), 634-642 (2020-01-10) ER stress induces epithelial differentiation in the mouse oesophagus.Sanne L Rosekrans et al.Gut, 64(2), 195-202 (2014-05-03) Improved IRE1 and PERK Pathway Sensors for Multiplex Endoplasmic Reticulum Stress Assay Reveal Stress Response to Nuclear Dyes Used for Image Segmentation.Adrien Nougarède et al.Assay and drug development technologies, 16(6), 350-360 (2018-08-09) Neuroprotective effect of noscapine on cerebral oxygen-glucose deprivation injury.Gelareh Vahabzadeh et al.Pharmacological reports : PR, 67(2), 281-288 (2015-02-26) Acute effect of bisphenol A: Signaling pathways on calcium influx in immature rat testes.Renata Gonçalves et al.Reproductive toxicology (Elmsford, N.Y.), 77, 94-102 (2018-02-25) STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy.Laura Navarro-Borelly et al.The Journal of physiology, 586(22), 5383-5401 (2008-10-04) Prolonged survival in pancreatic cancer patients with increased regucalcin gene expression: Overexpression of regucalcin suppresses the proliferation in human pancreatic cancer MIA PaCa-2 cells in vitro.Masayoshi Yamaguchi et al.International journal of oncology, 48(5), 1955-1964 (2016-03-05) Loss of Ca2+ entry via Orai-TRPC1 induces ER stress, initiating immune activation in macrophages.Viviane Nascimento Da Conceicao et al.Journal of cell science, 133(5) (2019-11-15) ATG5 Promotes Death Signaling in Response to the Cyclic Depsipeptides Coibamide A and Apratoxin A.Xuemei Wan et al.Marine drugs, 16(3) (2018-03-02) Revealing calcium fluxes by analyzing inhibition dynamics in action potential clamp.Martin Laasmaa et al.Journal of molecular and cellular cardiology, 100, 93-108 (2016-10-25) ORAI2 modulates store-operated calcium entry and T cell-mediated immunity.Martin Vaeth et al.Nature communications, 8, 14714-14714 (2017-03-16) Dual-Mode Optical Sensing of Histamine at Nanomolar Concentrations in Complex Biological Fluids and Living Cells.Nilanjan Dey et al.Chemistry (Weinheim an der Bergstrasse, Germany), 23(49), 11891-11897 (2017-06-16) A new role for HERPUD1 and ERAD activation in osteoblast differentiation and mineralization.Luan Américo-Da-Silva et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(9), 4681-4695 (2018-03-24) Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate.Tsun-Kai Chang et al.Molecular cell, 71(4), 629-636 (2018-08-18) Conventional protein kinase C isoforms differentially regulate ADP- and thrombin-evoked Ca²⁺ signalling in human platelets.Robert A Lever et al.Cell calcium, 58(6), 577-588 (2015-10-06) SILAC-based quantitative proteomics using mass spectrometry quantifies endoplasmic reticulum stress in whole HeLa cells.Daniel N Itzhak et al.Disease models & mechanisms, 12(11) (2019-10-20) Large-Scale Screening of Natural Products Transactivating Peroxisome Proliferator-Activated Receptor α Identifies 9S-Hydroxy-10E,12Z,15Z-Octadecatrienoic Acid and Cymarin as Potential Compounds Capable of Increasing Apolipoprotein A-I Transcription in Human Liver Cells.Sophie E van der Krieken et al.Lipids, 53(11-12), 1021-1030 (2019-02-02) PERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation.Gordon P Meares et al.Molecular and cellular biology, 34(20), 3911-3925 (2014-08-13) Shear stress-induced nuclear shrinkage through activation of Piezo1 channels in epithelial cells.Deekshitha Jetta et al.Journal of cell science, 132(11) (2019-05-12) Neuromedin U suppresses insulin secretion by triggering mitochondrial dysfunction and endoplasmic reticulum stress in pancreatic β-cells.Weidong Zhang et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(1), 133-147 (2020-01-10) CaMKII Potentiates Store-Operated Ca2+ Entry Through Enhancing STIM1 Aggregation and Interaction with Orai1.Shu Li et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 46(3), 1042-1054 (2018-04-19) Two different avian cold-sensitive sensory neurons: Transient receptor potential melastatin 8 (TRPM8)-dependent and -independent activation mechanisms.A Yamamoto et al.Neuropharmacology, 111, 130-141 (2016-09-04) Mangiferin inhibits endoplasmic reticulum stress-associated thioredoxin-interacting protein/NLRP3 inflammasome activation with regulation of AMPK in endothelial cells.Junna Song et al.Metabolism: clinical and experimental, 64(3), 428-437 (2014-12-17) Primary cilium loss in mammalian cells occurs predominantly by whole-cilium shedding.Mary Mirvis et al.PLoS biology, 17(7), e3000381-e3000381 (2019-07-18) CXCL1 activates TRPV1 via Gi/o protein and actin filaments.Alexandru Florian Deftu et al.Life sciences, 193, 282-291 (2017-10-03) Astragaloside-IV Protects Against Heat-induced Apoptosis by Inhibiting Excessive Activation of Mitochondrial Ca2+ Uniporter.Zhiwei Dong et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 42(2), 480-494 (2017-06-05) Short-term high-glucose treatment decreased abundance of Orai1 protein through posttranslational mechanisms in rat mesangial cells.Hui Jiang et al.American journal of physiology. Renal physiology, 314(5), F855-F863 (2018-01-25) The integrated stress response promotes B7H6 expression.Akram Obiedat et al.Journal of molecular medicine (Berlin, Germany), 98(1), 135-148 (2019-12-16) Capsaicin Induces ATF4 Translation with Upregulation of CHOP, GADD34 and PUMA.Misato Moriguchi et al.Biological & pharmaceutical bulletin, 42(8), 1428-1432 (2019-08-02) Knockdown of glucose-regulated protein 78 enhances poly(ADP-ribose) polymerase cleavage in human pancreatic cancer cells exposed to endoplasmic reticulum stress.Xia Jiang et al.Oncology reports, 32(6), 2343-2348 (2014-10-22) Tolvaptan activates the Nrf2/HO-1 antioxidant pathway through PERK phosphorylation.Tamami Fujiki et al.Scientific reports, 9(1), 9245-9245 (2019-06-27) Intracellular Bacterial Pathogens Trigger the Formation of U Small Nuclear RNA Bodies (U Bodies) through Metabolic Stress Induction.Jessica Tsalikis et al.The Journal of biological chemistry, 290(34), 20904-20918 (2015-07-03) Protein disulfide isomerase inhibition synergistically enhances the efficacy of sorafenib for hepatocellular carcinoma.Jae-Kyung Won et al.Hepatology (Baltimore, Md.), 66(3), 855-868 (2017-04-26) Mitochondrial division inhibitor-1 induces mitochondrial hyperfusion and sensitizes human cancer cells to TRAIL-induced apoptosis.Mamoru Akita et al.International journal of oncology, 45(5), 1901-1912 (2014-09-02) IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment.Jonathan M Harnoss et al.Cancer research, 80(11), 2368-2379 (2020-04-09) CRELD1 modulates homeostasis of the immune system in mice and humans.Lorenzo Bonaguro et al.Nature immunology, 21(12), 1517-1527 (2020-11-11) Cytoplasmic Restriction of Mutated SOD1 Impairs the DNA Repair Process in Spinal Cord Neurons.Jiaojie Li et al.Cells, 8(12) (2019-11-28) Activating transcription factor 6-dependent sestrin 2 induction ameliorates ER stress-mediated liver injury.Kyung Hwan Jegal et al.Biochimica et biophysica acta, 1864(7), 1295-1307 (2017-04-24) Pharmacological dose of melatonin reduces cytosolic calcium load in response to cholecystokinin in mouse pancreatic acinar cells.Patricia Santofimia-Castaño et al.Molecular and cellular biochemistry, 397(1-2), 75-86 (2014-08-03) Peroxisome proliferator-activated receptor α (PPARα)-dependent regulation of fibroblast growth factor 23 (FGF23).Franz Ewendt et al.Pflugers Archiv : European journal of physiology, 472(4), 503-511 (2020-03-20) MURC/CAVIN-4 facilitates store-operated calcium entry in neonatal cardiomyocytes.Julien Malette et al.Biochimica et biophysica acta. Molecular cell research, 1866(8), 1249-1259 (2019-04-06) A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cells.Benjamin G Gowen et al.eLife, 4 (2015-11-14) Calmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers.Xin Li et al.Nature communications, 8(1), 1042-1042 (2017-10-21) Activation of TRPC6 channels contributes to (+)-conocarpan-induced apoptotic cell death in HK-2 cells.Guoling Yang et al.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 129, 281-290 (2019-05-06) Fine tuning of the unfolded protein response by ISRIB improves neuronal survival in a model of amyotrophic lateral sclerosis.Ricardo Bugallo et al.Cell death & disease, 11(5), 397-397 (2020-05-28) PERK and XBP1 differentially regulate CXCL10 and CCL2 production.Shuang Zhu et al.Experimental eye research, 155, 1-14 (2017-01-10) Mechanosensitive store-operated calcium entry regulates the formation of cell polarity.Yi-Wei Huang et al.Journal of cellular physiology, 230(9), 2086-2097 (2015-02-03) Decreased contraction induced by endothelium-derived contracting factor in prolonged treatment of rat renal artery with endoplasmic reticulum stress inducer.Makoto Ando et al.Naunyn-Schmiedeberg's archives of pharmacology, 391(8), 793-802 (2018-05-08) Chorein Sensitive Orai1 Expression and Store Operated Ca2+ Entry in Rhabdomyosarcoma Cells.Willi Yu et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 40(5), 1141-1152 (2016-12-14) Selective deficiency in endothelial PTP1B protects from diabetes and endoplasmic reticulum stress-associated endothelial dysfunction via preventing endothelial cell apoptosis.Samuel Legeay et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 127, 110200-110200 (2020-05-18) Hepatitis C virus nonstructural protein 5A inhibits thapsigargin-induced apoptosis.Xia Jiang et al.PloS one, 9(11), e113499-e113499 (2014-11-20) Protective Effects of Glucose-Related Protein 78 and 94 on Cisplatin-Mediated Ototoxicity.Junyeong Yi et al.Antioxidants (Basel, Switzerland), 9(8) (2020-08-05) Nicotine-induced cellular stresses and autophagy in human cancer colon cells: A supportive effect on cell homeostasis via up-regulation of Cox-2 and PGE(2) production.Marjolaine A Pelissier-Rota et al.The international journal of biochemistry & cell biology, 65, 239-256 (2015-06-24) The Hypoxia Tolerance of the Goldfish (Carassius auratus) Heart: The NOS/NO System and Beyond.Mariacristina Filice et al.Antioxidants (Basel, Switzerland), 9(6) (2020-07-02) ER stress-mediated autophagic cell death induction through methylated β-cyclodextrins-threaded acid-labile polyrotaxanes.Kei Nishida et al.Journal of controlled release : official journal of the Controlled Release Society, 275, 20-31 (2018-02-13) Sodium tanshinone IIA sulfonate stimulated Cl- secretion in mouse trachea.Peng-Xiao Chen et al.PloS one, 12(5), e0178226-e0178226 (2017-05-26) Secretory stressors induce intracellular death receptor accumulation to control apoptosis.Bram J van Raam et al.Cell death & disease, 8(10), e3069-e3069 (2017-10-06) Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS.Anna Emde et al.The EMBO journal, 34(21), 2633-2651 (2015-09-04) Effect and mechanisms of celastrol on the apoptosis of HOS osteosarcoma cells.Yanyang Chen et al.Oncology reports, 40(4), 2260-2268 (2018-08-15) Stress-induced dissociations between intracellular calcium signaling and insulin secretion in pancreatic islets.Farhan M Qureshi et al.Cell calcium, 57(5-6), 366-375 (2015-04-12) Neochromine S5 improves contact hypersensitivity through a selective effect on activated T lymphocytes.Zhe Gao et al.Biochemical pharmacology, 92(2), 358-368 (2014-09-15) Neutrophil elastase induces MUC5AC secretion via protease-activated receptor 2.Jia Zhou et al.Molecular and cellular biochemistry, 377(1-2), 75-85 (2013-02-09) Empagliflozin dilates the rabbit aorta by activating PKG and voltage-dependent K+ channels.Mi Seon Seo et al.Toxicology and applied pharmacology, 403, 115153-115153 (2020-07-28) Isolated pores dissected from human two-pore channel 2 are functional.Christopher J Penny et al.Scientific reports, 6, 38426-38426 (2016-12-13) Cross-linking of glycosphingolipids at the plasma membrane: consequences for intracellular signaling and traffic.Tove Irene Klokk et al.Cellular and molecular life sciences : CMLS, 73(6), 1301-1316 (2015-09-27) Oxovanadium-based inhibitors can drive redox-sensitive cytotoxicity in neuroblastoma cells and synergise strongly with buthionine sulfoximine.Owen Clark et al.Cancer letters, 357(1), 316-327 (2014-12-03) HDAC6 Inhibition Promotes Transcription Factor EB Activation and Is Protective in Experimental Kidney Disease.Angela S Brijmohan et al.Frontiers in pharmacology, 9, 34-34 (2018-02-17) Chloroquine Promotes the Recovery of Acute Spinal Cord Injury by Inhibiting Autophagy-Associated Inflammation and Endoplasmic Reticulum Stress.Fenzan Wu et al.Journal of neurotrauma, 35(12), 1329-1344 (2018-01-11) Constriction of the mitochondrial inner compartment is a priming event for mitochondrial division.Bongki Cho et al.Nature communications, 8, 15754-15754 (2017-06-10) Selective Targeting of Myeloid-Derived Suppressor Cells in Cancer Patients Using DS-8273a, an Agonistic TRAIL-R2 Antibody.George A Dominguez et al.Clinical cancer research : an official journal of the American Association for Cancer Research, 23(12), 2942-2950 (2016-12-15) The Diabetes Gene JAZF1 Is Essential for the Homeostatic Control of Ribosome Biogenesis and Function in Metabolic Stress.Ahmad Kobiita et al.Cell reports, 32(1), 107846-107846 (2020-07-09) Lovastatin blocks Kv1.3 channel in human T cells: a new mechanism to explain its immunomodulatory properties.Ning Zhao et al.Scientific reports, 5, 17381-17381 (2015-12-01) The kinase receptor-interacting protein 1 is required for inflammasome activation induced by endoplasmic reticulum stress.Liang Tao et al.Cell death & disease, 9(6), 641-641 (2018-05-31) Upregulation of Runt-Related Transcription Factor-2 Through CCAAT Enhancer Binding Protein-β Signaling Pathway in Microglial BV-2 Cells Exposed to ATP.Ryota Nakazato et al.Journal of cellular physiology, 230(10), 2510-2521 (2015-03-25) Small molecule RL71 targets SERCA2 at a novel site in the treatment of human colorectal cancer.Baofang Yang et al.Oncotarget, 6(35), 37613-37625 (2015-11-27) Mitochondria Redistribution in Enterovirus A71 Infected Cells and Its Effect on Virus Replication.Yang Yang et al.Virologica Sinica, 34(4), 397-411 (2019-05-10) STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia.Shella Saint Fleur-Lominy et al.Cell reports, 24(11), 3045-3060 (2018-09-13) Depot-specific UCP1 expression in human white adipose tissue and its association with obesity-related markers.Jisun Lim et al.International journal of obesity (2005), 44(3), 697-706 (2020-01-23) CETSA beyond Soluble Targets: a Broad Application to Multipass Transmembrane Proteins.Aarti Kawatkar et al.ACS chemical biology, 14(9), 1913-1920 (2019-07-23) Prevention of Injury-Induced Osteoarthritis in Rodent Temporomandibular Joint by Targeting Chondrocyte CaSR.Mian Zhang et al.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 34(4), 726-738 (2018-11-30) HDL inhibits endoplasmic reticulum stress-induced apoptosis of pancreatic β-cells in vitro by activation of Smoothened.Mustafa Yalcinkaya et al.Journal of lipid research, 61(4), 492-504 (2020-01-08) Notoginsenoside R1 Alleviates Oxygen-Glucose Deprivation/Reoxygenation Injury by Suppressing Endoplasmic Reticulum Calcium Release via PLC.Yan Wang et al.Scientific reports, 7(1), 16226-16226 (2017-11-28) Cell-free DNA release by mouse placental explants.Mark Phillippe et al.PloS one, 12(6), e0178845-e0178845 (2017-06-18) Reduced Endoplasmic Reticulum Stress-Mediated Autophagy Is Required for Leptin Alleviating Inflammation in Adipose Tissue.Lu Gan et al.Frontiers in immunology, 8, 1507-1507 (2017-12-19) Functional analysis of protein disulfide isomerase P5 in glioblastoma cells as a novel anticancer target.Tomohisa Horibe et al.Oncology reports, 41(2), 961-972 (2018-11-16) TRPM7 Mediates Mechanosensitivity in Adult Rat Odontoblasts.J Won et al.Journal of dental research, 97(9), 1039-1046 (2018-03-01) Vitamin K2 induces non-apoptotic cell death along with autophagosome formation in breast cancer cell lines.Shinsuke Miyazawa et al.Breast cancer (Tokyo, Japan), 27(2), 225-235 (2019-10-19) Structure-function relationships of HDL in diabetes and coronary heart disease.Mathias Cardner et al.JCI insight, 5(1) (2019-12-13) Compromised astrocyte function and survival negatively impact neurons in infantile neuronal ceroid lipofuscinosis.Jenny Lange et al.Acta neuropathologica communications, 6(1), 74-74 (2018-08-10) Effects of San-Huang-Xie-Xin-tang, a traditional Chinese prescription for clearing away heat and toxin, on the pacemaker activities of interstitial cells of Cajal from the murine small intestine.Byung Joo Kim et al.Journal of ethnopharmacology, 155(1), 744-752 (2014-06-24) SK3 Gene Polymorphism Is Associated with Taxane Neurotoxicity and Cell Calcium Homeostasis.Carina Rua et al.Clinical cancer research : an official journal of the American Association for Cancer Research, 24(21), 5313-5320 (2018-07-25) Novel Role of Macrophage Migration Inhibitory Factor in Upstream Control of the Unfolded Protein Response After Ethanol Feeding in Mice.Kyle Lauren Poulsen et al.Alcoholism, clinical and experimental research, 43(7), 1439-1451 (2019-04-23) Immunoassay for determination of trilobolide.Lukáš Huml et al.Steroids, 117, 105-111 (2016-09-08) Role of X-Box Binding Protein-1 in Fructose-Induced De Novo Lipogenesis in HepG2 Cells.Xian Yu et al.Chinese medical journal, 131(19), 2310-2319 (2018-09-25) Release of ATP by pre-Bötzinger complex astrocytes contributes to the hypoxic ventilatory response via a Ca2+ -dependent P2Y1 receptor mechanism.Vishaal Rajani et al.The Journal of physiology, 596(15), 3245-3269 (2017-07-06) Repression of Mcl-1 and disruption of the Mcl-1/Bak interaction in myeloma cells couple ER stress to mitochondrial apoptosis.Patricia Gomez-Bougie et al.Cancer letters, 383(2), 204-211 (2016-10-25) TRPV4 channels stimulate Ca2+-induced Ca2+ release in mouse neurons and trigger endoplasmic reticulum stress after intracerebral hemorrhage.Jingjing Shen et al.Brain research bulletin, 146, 143-152 (2018-12-07) Xanthohumol Improves Diet-induced Obesity and Fatty Liver by Suppressing Sterol Regulatory Element-binding Protein (SREBP) Activation.Shingo Miyata et al.The Journal of biological chemistry, 290(33), 20565-20579 (2015-07-05) Over-expression of X-linked inhibitor of apoptosis protein modulates multiple aspects of neuronal Ca2+ signaling.Jeff Grant et al.Neurochemical research, 38(4), 847-856 (2013-02-12) Thapsigargin, a high affinity and global inhibitor of intracellular Ca2+ transport ATPases.G Inesi et al.Archives of biochemistry and biophysics, 298(2), 313-317 (1992-11-01) 3,4-dihydroxybenzalacetone and caffeic acid phenethyl ester induce preconditioning ER stress and autophagy in SH-SY5Y cells.Ryoichi Tomiyama et al.Journal of cellular physiology, 233(2), 1671-1684 (2017-07-07) Mild endoplasmic reticulum stress promotes retinal neovascularization via induction of BiP/GRP78.Shinsuke Nakamura et al.PloS one, 8(3), e60517-e60517 (2013-04-02) Curcumin attenuates glutamate neurotoxicity in the hippocampus by suppression of ER stress-associated TXNIP/NLRP3 inflammasome activation in a manner dependent on AMPK.Ying Li et al.Toxicology and applied pharmacology, 286(1), 53-63 (2015-03-21) Phosphorylation within the bipartite NLS alters the localization and toxicity of the ER stress response factor DDIT3/CHOP.Jonathan C Bartko et al.Cellular signalling, 74, 109713-109713 (2020-07-17) Sodium tanshinone IIA sulfonate stimulated Cl- secretion in mouse trachea.Peng-Xiao Chen et al.PloS one, 12(5), e0178226-e0178226 (2017-05-26) Secretory stressors induce intracellular death receptor accumulation to control apoptosis.Bram J van Raam et al.Cell death & disease, 8(10), e3069-e3069 (2017-10-06) Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS.Anna Emde et al.The EMBO journal, 34(21), 2633-2651 (2015-09-04) Effect and mechanisms of celastrol on the apoptosis of HOS osteosarcoma cells.Yanyang Chen et al.Oncology reports, 40(4), 2260-2268 (2018-08-15) Mitochondria Redistribution in Enterovirus A71 Infected Cells and Its Effect on Virus Replication.Yang Yang et al.Virologica Sinica, 34(4), 397-411 (2019-05-10) STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia.Shella Saint Fleur-Lominy et al.Cell reports, 24(11), 3045-3060 (2018-09-13) Neochromine S5 improves contact hypersensitivity through a selective effect on activated T lymphocytes.Zhe Gao et al.Biochemical pharmacology, 92(2), 358-368 (2014-09-15) Neutrophil elastase induces MUC5AC secretion via protease-activated receptor 2.Jia Zhou et al.Molecular and cellular biochemistry, 377(1-2), 75-85 (2013-02-09) Empagliflozin dilates the rabbit aorta by activating PKG and voltage-dependent K+ channels.Mi Seon Seo et al.Toxicology and applied pharmacology, 403, 115153-115153 (2020-07-28) Isolated pores dissected from human two-pore channel 2 are functional.Christopher J Penny et al.Scientific reports, 6, 38426-38426 (2016-12-13) Cross-linking of glycosphingolipids at the plasma membrane: consequences for intracellular signaling and traffic.Tove Irene Klokk et al.Cellular and molecular life sciences : CMLS, 73(6), 1301-1316 (2015-09-27) Oxovanadium-based inhibitors can drive redox-sensitive cytotoxicity in neuroblastoma cells and synergise strongly with buthionine sulfoximine.Owen Clark et al.Cancer letters, 357(1), 316-327 (2014-12-03) N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis.Yann Estornes et al.Cell death & disease, 9(5), 494-494 (2018-05-03) Constriction of the mitochondrial inner compartment is a priming event for mitochondrial division.Bongki Cho et al.Nature communications, 8, 15754-15754 (2017-06-10) HDAC6 Inhibition Promotes Transcription Factor EB Activation and Is Protective in Experimental Kidney Disease.Angela S Brijmohan et al.Frontiers in pharmacology, 9, 34-34 (2018-02-17) Chloroquine Promotes the Recovery of Acute Spinal Cord Injury by Inhibiting Autophagy-Associated Inflammation and Endoplasmic Reticulum Stress.Fenzan Wu et al.Journal of neurotrauma, 35(12), 1329-1344 (2018-01-11) Small molecule RL71 targets SERCA2 at a novel site in the treatment of human colorectal cancer.Baofang Yang et al.Oncotarget, 6(35), 37613-37625 (2015-11-27) Depot-specific UCP1 expression in human white adipose tissue and its association with obesity-related markers.Jisun Lim et al.International journal of obesity (2005), 44(3), 697-706 (2020-01-23) CETSA beyond Soluble Targets: a Broad Application to Multipass Transmembrane Proteins.Aarti Kawatkar et al.ACS chemical biology, 14(9), 1913-1920 (2019-07-23) Prevention of Injury-Induced Osteoarthritis in Rodent Temporomandibular Joint by Targeting Chondrocyte CaSR.Mian Zhang et al.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 34(4), 726-738 (2018-11-30) Selective Targeting of Myeloid-Derived Suppressor Cells in Cancer Patients Using DS-8273a, an Agonistic TRAIL-R2 Antibody.George A Dominguez et al.Clinical cancer research : an official journal of the American Association for Cancer Research, 23(12), 2942-2950 (2016-12-15) The Diabetes Gene JAZF1 Is Essential for the Homeostatic Control of Ribosome Biogenesis and Function in Metabolic Stress.Ahmad Kobiita et al.Cell reports, 32(1), 107846-107846 (2020-07-09) Lovastatin blocks Kv1.3 channel in human T cells: a new mechanism to explain its immunomodulatory properties.Ning Zhao et al.Scientific reports, 5, 17381-17381 (2015-12-01) The kinase receptor-interacting protein 1 is required for inflammasome activation induced by endoplasmic reticulum stress.Liang Tao et al.Cell death & disease, 9(6), 641-641 (2018-05-31) Upregulation of Runt-Related Transcription Factor-2 Through CCAAT Enhancer Binding Protein-β Signaling Pathway in Microglial BV-2 Cells Exposed to ATP.Ryota Nakazato et al.Journal of cellular physiology, 230(10), 2510-2521 (2015-03-25) HDL inhibits endoplasmic reticulum stress-induced apoptosis of pancreatic β-cells in vitro by activation of Smoothened.Mustafa Yalcinkaya et al.Journal of lipid research, 61(4), 492-504 (2020-01-08) Notoginsenoside R1 Alleviates Oxygen-Glucose Deprivation/Reoxygenation Injury by Suppressing Endoplasmic Reticulum Calcium Release via PLC.Yan Wang et al.Scientific reports, 7(1), 16226-16226 (2017-11-28) Role of X-Box Binding Protein-1 in Fructose-Induced De Novo Lipogenesis in HepG2 Cells.Xian Yu et al.Chinese medical journal, 131(19), 2310-2319 (2018-09-25) Release of ATP by pre-Bötzinger complex astrocytes contributes to the hypoxic ventilatory response via a Ca2+ -dependent P2Y1 receptor mechanism.Vishaal Rajani et al.The Journal of physiology, 596(15), 3245-3269 (2017-07-06) Repression of Mcl-1 and disruption of the Mcl-1/Bak interaction in myeloma cells couple ER stress to mitochondrial apoptosis.Patricia Gomez-Bougie et al.Cancer letters, 383(2), 204-211 (2016-10-25) TRPV4 channels stimulate Ca2+-induced Ca2+ release in mouse neurons and trigger endoplasmic reticulum stress after intracerebral hemorrhage.Jingjing Shen et al.Brain research bulletin, 146, 143-152 (2018-12-07) Reduced Endoplasmic Reticulum Stress-Mediated Autophagy Is Required for Leptin Alleviating Inflammation in Adipose Tissue.Lu Gan et al.Frontiers in immunology, 8, 1507-1507 (2017-12-19) Functional analysis of protein disulfide isomerase P5 in glioblastoma cells as a novel anticancer target.Tomohisa Horibe et al.Oncology reports, 41(2), 961-972 (2018-11-16) TRPM7 Mediates Mechanosensitivity in Adult Rat Odontoblasts.J Won et al.Journal of dental research, 97(9), 1039-1046 (2018-03-01) Vitamin K2 induces non-apoptotic cell death along with autophagosome formation in breast cancer cell lines.Shinsuke Miyazawa et al.Breast cancer (Tokyo, Japan), 27(2), 225-235 (2019-10-19) Structure-function relationships of HDL in diabetes and coronary heart disease.Mathias Cardner et al.JCI insight, 5(1) (2019-12-13) Xanthohumol Improves Diet-induced Obesity and Fatty Liver by Suppressing Sterol Regulatory Element-binding Protein (SREBP) Activation.Shingo Miyata et al.The Journal of biological chemistry, 290(33), 20565-20579 (2015-07-05) Compromised astrocyte function and survival negatively impact neurons in infantile neuronal ceroid lipofuscinosis.Jenny Lange et al.Acta neuropathologica communications, 6(1), 74-74 (2018-08-10) Effects of San-Huang-Xie-Xin-tang, a traditional Chinese prescription for clearing away heat and toxin, on the pacemaker activities of interstitial cells of Cajal from the murine small intestine.Byung Joo Kim et al.Journal of ethnopharmacology, 155(1), 744-752 (2014-06-24) The tyrosine kinase inhibitor bafetinib inhibits PAR2-induced activation of TRPV4 channels in vitro and pain in vivo.M S Grace et al.British journal of pharmacology, 171(16), 3881-3894 (2014-05-02) The N-Degron Pathway Mediates ER-phagy.Chang Hoon Ji et al.Molecular cell, 75(5), 1058-1072 (2019-08-04) Mitochondrial (dys)function - a factor underlying the variability of efavirenz-induced hepatotoxicity?M Polo et al.British journal of pharmacology, 172(7), 1713-1727 (2014-11-21) Organelle Optogenetics: Direct Manipulation of Intracellular Ca2+ Dynamics by Light.Toshifumi Asano et al.Frontiers in neuroscience, 12, 561-561 (2018-09-04) Lycorine Promotes Autophagy and Apoptosis via TCRP1/Akt/mTOR Axis Inactivation in Human Hepatocellular Carcinoma.Haiyang Yu et al.Molecular cancer therapeutics, 16(12), 2711-2723 (2017-10-05) Sensing intracellular calcium ions using a manganese-based MRI contrast agent.Ali Barandov et al.Nature communications, 10(1), 897-897 (2019-02-24) Over-expression of X-linked inhibitor of apoptosis protein modulates multiple aspects of neuronal Ca2+ signaling.Jeff Grant et al.Neurochemical research, 38(4), 847-856 (2013-02-12) Thapsigargin, a high affinity and global inhibitor of intracellular Ca2+ transport ATPases.G Inesi et al.Archives of biochemistry and biophysics, 298(2), 313-317 (1992-11-01) 3,4-dihydroxybenzalacetone and caffeic acid phenethyl ester induce preconditioning ER stress and autophagy in SH-SY5Y cells.Ryoichi Tomiyama et al.Journal of cellular physiology, 233(2), 1671-1684 (2017-07-07) Mild endoplasmic reticulum stress promotes retinal neovascularization via induction of BiP/GRP78.Shinsuke Nakamura et al.PloS one, 8(3), e60517-e60517 (2013-04-02) Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21.Maitea Guridi et al.Science signaling, 8(402), ra113-ra113 (2015-11-12) Curcumin attenuates glutamate neurotoxicity in the hippocampus by suppression of ER stress-associated TXNIP/NLRP3 inflammasome activation in a manner dependent on AMPK.Ying Li et al.Toxicology and applied pharmacology, 286(1), 53-63 (2015-03-21) Mitotane Inhibits Sterol-O-Acyl Transferase 1 Triggering Lipid-Mediated Endoplasmic Reticulum Stress and Apoptosis in Adrenocortical Carcinoma Cells.Silviu Sbiera et al.Endocrinology, 156(11), 3895-3908 (2015-08-26) Endoplasmic reticulum stress cooperates with Toll-like receptor ligation in driving activation of rheumatoid arthritis fibroblast-like synoviocytes.Pawel A Kabala et al.Arthritis research & therapy, 19(1), 207-207 (2017-09-20) Store-independent coupling between the Secretory Pathway Ca2+ transport ATPase SPCA1 and Orai1 in Golgi stress and Hailey-Hailey disease.Susanne Smaardijk et al.Biochimica et biophysica acta. Molecular cell research, 1865(6), 855-862 (2018-03-21) Chronic high fat feeding restricts islet mRNA translation initiation independently of ER stress via DNA damage and p53 activation.Masayuki Hatanaka et al.Scientific reports, 7(1), 3758-3758 (2017-06-21) Phosphorylation within the bipartite NLS alters the localization and toxicity of the ER stress response factor DDIT3/CHOP.Jonathan C Bartko et al.Cellular signalling, 74, 109713-109713 (2020-07-17) Mechanism of the vasorelaxant effect induced by trans-4-methyl-β-nitrostyrene, a synthetic nitroderivative, in rat thoracic aorta.Taylena Maria Teófilo et al.Clinical and experimental pharmacology & physiology, 44(7), 787-794 (2017-04-23) HPW-RX40 prevents human platelet activation by attenuating cell surface protein disulfide isomerases.Po-Hsiung Kung et al.Redox biology, 13, 266-277 (2017-06-11) Antitumor effects of a sirtuin inhibitor, tenovin-6, against gastric cancer cells via death receptor 5 up-regulation.Sachiko Hirai et al.PloS one, 9(7), e102831-e102831 (2014-07-18) Endogenous TRPC channels mediate Ca2+ signals and trigeminal synaptic plasticity induced by mGluR5.Dong-Ho Youn et al.Life sciences, 231, 116567-116567 (2019-06-17) Pharmacological characterization of the orexin/hypocretin receptor agonist Nag 26.Maiju K Rinne et al.European journal of pharmacology, 837, 137-144 (2018-09-09) SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells.Su-Wei Xu et al.Pharmacological research, 153, 104660-104660 (2020-01-27) Protective Effect of Purple Tomato Anthocyanidin on Chromium(VI)-Induced Autophagy in LMH Cells by Inhibiting Endoplasmic Reticulum Stress.Kangping Liu et al.Biological trace element research, 194(2), 570-580 (2019-07-03) Neurite atrophy and apoptosis mediated by PERK signaling after accumulation of GM2-ganglioside.María José Virgolini et al.Biochimica et biophysica acta. Molecular cell research, 1866(2), 225-239 (2018-11-06) Neuronal Chloride Regulation via KCC2 Is Modulated through a GABAB Receptor Protein Complex.Rebecca Wright et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 37(22), 5447-5462 (2017-04-30) Interferon-τ regulates prostaglandin release in goat endometrial stromal cells via JAB1 - unfolded protein response pathway.Diqi Yang et al.Theriogenology, 113, 237-246 (2018-03-25) Stearic acid at physiologic concentrations induces in vitro lipotoxicity in circulating angiogenic cells.Valentina Spigoni et al.Atherosclerosis, 265, 162-171 (2017-09-12) Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy.Moran Dvela-Levitt et al.Cell, 178(3), 521-535 (2019-07-28) Dose-dependent effects of angiotensin-(1-7) on the NHE3 exchanger and [Ca(2+)](i) in in vivo proximal tubules.Regiane C Castelo-Branco et al.American journal of physiology. Renal physiology, 304(10), F1258-F1265 (2013-03-22) A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation.Jin Rui Liang et al.Cell, 180(6), 1160-1177 (2020-03-12) Curcumin attenuates palmitic acid-induced cell apoptosis by inhibiting endoplasmic reticulum stress in H9C2 cardiomyocytes.G Guan et al.Human & experimental toxicology, 38(6), 655-664 (2019-03-13) Rapid sensing of l-leucine by human and murine hypothalamic neurons: Neurochemical and mechanistic insights.Nicholas Heeley et al.Molecular metabolism, 10, 14-27 (2018-02-15) Elevated Endoplasmic Reticulum Stress Response Contributes to Adipose Tissue Inflammation in Aging.Amiya Kumar Ghosh et al.The journals of gerontology. Series A, Biological sciences and medical sciences, 70(11), 1320-1329 (2014-10-18) Agonist-dependent modulation of cell surface expression of the cold receptor TRPM8.Carlos A Toro et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(2), 571-582 (2015-01-16) Endoplasmic reticulum stress mediates the anti-inflammatory effect of ethyl pyruvate in endothelial cells.Ge Wang et al.PloS one, 9(12), e113983-e113983 (2014-12-04) Inhibition of the mevalonate pathway by simvastatin interferes with mast cell degranulation by disrupting the interaction between Rab27a and double C2 alpha proteins.Muhammad Novrizal Abdi Sahid et al.European journal of pharmacology, 814, 255-263 (2017-09-03) A Kinetic Characterization of the Gill (NaDaniel L Farias et al.The Journal of membrane biology, 250(5), 517-534 (2017-08-26) Schekwanglupaside C, a new lupane saponin from Schefflera kwangsiensis, is a potent activator of sarcoplasmic reticulum Ca2+-ATPase.Guolin Yang et al.Fitoterapia, 137, 104150-104150 (2019-04-18) Spectral Unmixing Plate Reader: High-Throughput, High-Precision FRET Assays in Living Cells.Tory M Schaaf et al.SLAS discovery : advancing life sciences R & D, 22(3), 250-261 (2016-11-24) Distinct signaling of Drosophila chemoreceptors in olfactory sensory neurons.Li-Hui Cao et al.Proceedings of the National Academy of Sciences of the United States of America, 113(7), E902-E911 (2016-02-03) Polystyrene nanoparticles activate ion transport in human airway epithelial cells.J McCarthy et al.International journal of nanomedicine, 6, 1343-1356 (2011-07-16) Transcriptional and epigenetic modulation of autophagy promotes EBV oncoprotein EBNA3C induced B-cell survival.Shaoni Bhattacharjee et al.Cell death & disease, 9(6), 605-605 (2018-05-24) Volume-regulated Cl- current: contributions of distinct Cl- channels and localized Ca2+ signals.Yani Liu et al.American journal of physiology. Cell physiology, 317(3), C466-C480 (2019-06-27) STIM1 controls calcineurin/Akt/mTOR/NFATC2-mediated osteoclastogenesis induced by RANKL/M-CSF.Yanjiao Huang et al.Experimental and therapeutic medicine, 20(2), 736-747 (2020-08-04) Induction of Herpud1 expression by ER stress is regulated by Nrf1.Daniel V Ho et al.FEBS letters, 589(5), 615-620 (2015-02-01) The sarcoplasmic reticulum Ca2+ pump: inhibition by thapsigargin and enhancement by adenovirus-mediated gene transfer.G Inesi et al.Annals of the New York Academy of Sciences, 853, 195-206 (1999-12-22) Signaling involved in PTTH-stimulated 4E-BP phosphorylation in prothoracic gland cells of Bombyx mori.Shi-Hong Gu et al.Journal of insect physiology, 96, 1-8 (2016-11-05) Comparison of the pharmacological profiles of arginine vasopressin and oxytocin analogs at marmoset, macaque, and human vasopressin 1a receptor.Marsha L Pierce et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 126, 110060-110060 (2020-03-08) Waves of calcium depletion in the sarcoplasmic reticulum of vascular smooth muscle cells: an inside view of spatiotemporal Ca2+ regulation.Mitra Esfandiarei et al.PloS one, 8(2), e55333-e55333 (2013-02-15) Brain-derived neurotrophic factor inhibits neuromuscular junction maturation mediated by inTracellular Ca(2+) and Ca(2+)/calmodulin-dependent kinase.Wei Song et al.Muscle & nerve, 53(4), 593-597 (2015-08-08) Transmembrane thioredoxin-related protein TMX1 is reversibly oxidized in response to protein accumulation in the endoplasmic reticulum.Yoshiyuki Matsuo et al.FEBS open bio, 7(11), 1768-1777 (2017-11-11) Complex phenotypes associated with STIM1 mutations in both coiled coil and EF-hand domains.Elizabeth Harris et al.Neuromuscular disorders : NMD, 27(9), 861-872 (2017-06-19) Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells.Martin Vaeth et al.Journal of immunology (Baltimore, Md. : 1950), 195(3), 1202-1217 (2015-06-26) Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy.Naoki Okumura et al.Investigative ophthalmology & visual science, 58(9), 3697-3707 (2017-07-21) Evidence that nitric oxide is a non-adrenergic non-cholinergic inhibitory neurotransmitter in the circular muscle of the mouse distal colon: a study on the mechanism of nitric oxide-induced relaxation.Kazuhiro Nishiyama et al.Pharmacology, 94(3-4), 99-108 (2014-09-18) Centrosome Amplification in Cancer Disrupts Autophagy and Sensitizes to Autophagy Inhibition.Ryan A Denu et al.Molecular cancer research : MCR, 18(1), 33-45 (2019-10-13) Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2.Jing Deng et al.Molecular and cellular biology, 24(23), 10161-10168 (2004-11-16) Interplay between the oxidoreductase PDIA6 and microRNA-322 controls the response to disrupted endoplasmic reticulum calcium homeostasis.Jody Groenendyk et al.Science signaling, 7(329), ra54-ra54 (2014-06-12) Clinical, histological and genetic characterisation of patients with tubular aggregate myopathy caused by mutations in STIM1.Johann Böhm et al.Journal of medical genetics, 51(12), 824-833 (2014-10-19) Sulfonyl(thio)urea derivative induction of insulin secretion is mediated by potassium, calcium, and sodium channel signal transduction.Paola Miranda Sulis et al.Journal of cellular physiology, 234(7), 10138-10147 (2018-11-13) Regulation of cardiac myocyte cohesion and gap junctions via desmosomal adhesion.Camilla Schinner et al.Acta physiologica (Oxford, England), 226(2), e13242-e13242 (2018-12-26) Interplay between synchronization of multivesicular release and recruitment of additional release sites support short-term facilitation at hippocampal mossy fiber to CA3 pyramidal cells synapses.Simon Chamberland et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(33), 11032-11047 (2014-08-15) Transient Cell Membrane Disruptions induce Calcium Waves in Corneal Keratocytes.Zhong Chen et al.Scientific reports, 10(1), 2840-2840 (2020-02-20) Histidine-rich calcium binding protein promotes growth of hepatocellular carcinoma in vitro and in vivo.Jingmei Liu et al.Cancer science, 106(10), 1288-1295 (2015-07-16) Stimulation of ORAI1 expression, store-operated Ca2+ entry, and osteogenic signaling by high glucose exposure of human aortic smooth muscle cells.Ke Ma et al.Pflugers Archiv : European journal of physiology, 472(8), 1093-1102 (2020-06-20) Cutting Edge: Protein Arginine Deiminase 2 and 4 Regulate NLRP3 Inflammasome-Dependent IL-1β Maturation and ASC Speck Formation in Macrophages.Neha Mishra et al.Journal of immunology (Baltimore, Md. : 1950), 203(4), 795-800 (2019-07-12) Carbon monoxide-releasing molecules reverse leptin resistance induced by endoplasmic reticulum stress.Min Zheng et al.American journal of physiology. Endocrinology and metabolism, 304(7), E780-E788 (2013-02-14) Prolonged survival in pancreatic cancer patients with increased regucalcin gene expression: Overexpression of regucalcin suppresses the proliferation in human pancreatic cancer MIA PaCa-2 cells in vitro.Masayoshi Yamaguchi et al.International journal of oncology, 48(5), 1955-1964 (2016-03-05) Loss of Ca2+ entry via Orai-TRPC1 induces ER stress, initiating immune activation in macrophages.Viviane Nascimento Da Conceicao et al.Journal of cell science, 133(5) (2019-11-15) ATG5 Promotes Death Signaling in Response to the Cyclic Depsipeptides Coibamide A and Apratoxin A.Xuemei Wan et al.Marine drugs, 16(3) (2018-03-02) Revealing calcium fluxes by analyzing inhibition dynamics in action potential clamp.Martin Laasmaa et al.Journal of molecular and cellular cardiology, 100, 93-108 (2016-10-25) ORAI2 modulates store-operated calcium entry and T cell-mediated immunity.Martin Vaeth et al.Nature communications, 8, 14714-14714 (2017-03-16) Role of glutamine and interlinked asparagine metabolism in vessel formation.Hongling Huang et al.The EMBO journal, 36(16), 2334-2352 (2017-07-01) Dystrophic cardiomyopathy: role of TRPV2 channels in stretch-induced cell damage.Charlotte Lorin et al.Cardiovascular research, 106(1), 153-162 (2015-01-27) TBL2 is a novel PERK-binding protein that modulates stress-signaling and cell survival during endoplasmic reticulum stress.Yoshinori Tsukumo et al.PloS one, 9(11), e112761-e112761 (2014-11-14) Molecular and functional identification of a mitochondrial ryanodine receptor in neurons.Regina Jakob et al.Neuroscience letters, 575, 7-12 (2014-05-28) Novel targets for Huntington's disease in an mTOR-independent autophagy pathway.Andrea Williams et al.Nature chemical biology, 4(5), 295-305 (2008-04-09) Acute Exercise Decreases Tribbles Homolog 3 Protein Levels in the Hypothalamus of Obese Rats.Barbara De Almeira Rodrigues et al.Medicine and science in sports and exercise, 47(8), 1613-1623 (2014-11-21) Puumala and Andes Orthohantaviruses Cause Transient Protein Kinase R-Dependent Formation of Stress Granules.Wanda Christ et al.Journal of virology, 94(3) (2019-11-15) XBP1 negatively regulates CENPF expression via recruiting ATF6α to the promoter during ER stress.Tao Shen et al.Cancer cell international, 20, 459-459 (2020-09-26) Dual-Mode Optical Sensing of Histamine at Nanomolar Concentrations in Complex Biological Fluids and Living Cells.Nilanjan Dey et al.Chemistry (Weinheim an der Bergstrasse, Germany), 23(49), 11891-11897 (2017-06-16) A new role for HERPUD1 and ERAD activation in osteoblast differentiation and mineralization.Luan Américo-Da-Silva et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(9), 4681-4695 (2018-03-24) Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate.Tsun-Kai Chang et al.Molecular cell, 71(4), 629-636 (2018-08-18) Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells.S Saveljeva et al.Cell death & disease, 6, e1587-e1587 (2015-01-09) Comparison of the pharmacological profiles of arginine vasopressin and oxytocin analogs at marmoset, macaque, and human vasopressin 1a receptor.Marsha L Pierce et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 126, 110060-110060 (2020-03-08) Waves of calcium depletion in the sarcoplasmic reticulum of vascular smooth muscle cells: an inside view of spatiotemporal Ca2+ regulation.Mitra Esfandiarei et al.PloS one, 8(2), e55333-e55333 (2013-02-15) Morphological change of CD4(+) T cell during contact with DC modulates T-cell activation by accumulation of F-actin in the immunology synapse.Wei Lin et al.BMC immunology, 16, 49-49 (2015-08-27) Overexpression of histone demethylase Fbxl10 leads to enhanced migration in mouse embryonic fibroblasts.Magdalena Rohde et al.Experimental cell research, 348(2), 123-131 (2016-10-25) Hypoxic stress up-regulates Kir2.1 expression and facilitates cell proliferation in brain capillary endothelial cells.Hideto Yamamura et al.Biochemical and biophysical research communications, 476(4), 386-392 (2016-05-29) The Endocannabinoid Metabolite Prostaglandin ECaroline Turcotte et al.Journal of immunology (Baltimore, Md. : 1950), 198(8), 3255-3263 (2017-03-05) Crosstalk between transforming growth factor-β1 and endoplasmic reticulum stress regulates alpha-smooth muscle cell actin expression in podocytes.Chien-An Chen et al.Life sciences, 209, 9-14 (2018-07-31) STIM1 Is Required for Remodeling of the Endoplasmic Reticulum and Microtubule Cytoskeleton in Steering Growth Cones.Macarena Pavez et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(26), 5095-5114 (2019-04-27) Arachidonic Acid Attenuates Cell Proliferation, Migration and Viability by a Mechanism Independent on Calcium Entry.Carlos Cantonero et al.International journal of molecular sciences, 21(9) (2020-05-13) SEC24A identified as an essential mediator of thapsigargin-induced cell death in a genome-wide CRISPR/Cas9 screen.Tamutenda Chidawanyika et al.Cell death discovery, 4, 115-115 (2018-12-28) USP15 Deubiquitinates TUT1 Associated with RNA Metabolism and Maintains Cerebellar Homeostasis.Jaehyun Kim et al.Molecular and cellular biology, 40(21) (2020-08-26) The p97 Inhibitor CB-5083 Is a Unique Disrupter of Protein Homeostasis in Models of Multiple Myeloma.Ronan Le Moigne et al.Molecular cancer therapeutics, 16(11), 2375-2386 (2017-09-08) Cationic liposomes suppress intracellular calcium ion concentration increase via inhibition of PI3 kinase pathway in mast cells.Yoshikazu Inoh et al.Biochimica et biophysica acta, 1859(12), 2461-2466 (2017-10-03) Termination of T cell priming relies on a phase of unresponsiveness promoting disengagement from APCs and T cell division.Armelle Bohineust et al.The Journal of experimental medicine, 215(5), 1481-1492 (2018-03-29) Constitutive and ligand-induced EGFR signalling triggers distinct and mutually exclusive downstream signalling networks.Sharmistha Chakraborty et al.Nature communications, 5, 5811-5811 (2014-12-17) ATP-sensitive K+ channels and mitochondrial permeability transition pore mediate effects of hydrogen sulfide on cytosolic Ca2+ homeostasis and insulin secretion in β-cells.Aizhu Lu et al.Pflugers Archiv : European journal of physiology, 471(11-12), 1551-1564 (2019-11-13) A potential new approach for treating systemic sclerosis: Dedifferentiation of SSc fibroblasts and change in the microenvironment by blocking store-operated Ca2+ entry.Ching-Ying Wu et al.PloS one, 14(3), e0213400-e0213400 (2019-03-15) Kaempferol induces autophagic cell death via IRE1-JNK-CHOP pathway and inhibition of G9a in gastric cancer cells.Tae Woo Kim et al.Cell death & disease, 9(9), 875-875 (2018-08-31) Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity.Samuel M Gonçalves et al.Nature communications, 11(1), 2282-2282 (2020-05-10) FKBP9 promotes the malignant behavior of glioblastoma cells and confers resistance to endoplasmic reticulum stress inducers.Huizhe Xu et al.Journal of experimental & clinical cancer research : CR, 39(1), 44-44 (2020-03-01) Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity.Chu-Xiao Liu et al.Cell, 177(4), 865-880 (2019-04-30) Rapid Upregulation of Orai1 Abundance in the Plasma Membrane of Platelets Following Activation with Thrombin and Collagen Related Peptide.Guilai Liu et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 37(5), 1759-1766 (2015-11-20) T Cell Subset and Stimulation Strength-Dependent Modulation of T Cell Activation by Kv1.3 Blockers.Wai-Ping Fung-Leung et al.PloS one, 12(1), e0170102-e0170102 (2017-01-21) A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation.Jin Rui Liang et al.Cell, 180(6), 1160-1177 (2020-03-12) Curcumin attenuates palmitic acid-induced cell apoptosis by inhibiting endoplasmic reticulum stress in H9C2 cardiomyocytes.G Guan et al.Human & experimental toxicology, 38(6), 655-664 (2019-03-13) Rapid sensing of l-leucine by human and murine hypothalamic neurons: Neurochemical and mechanistic insights.Nicholas Heeley et al.Molecular metabolism, 10, 14-27 (2018-02-15) Role of caspase-3 cleaved IP3 R1 on Ca(2+) homeostasis and developmental competence of mouse oocytes and eggs.Nan Zhang et al.Journal of cellular physiology, 229(11), 1842-1854 (2014-04-03) Endoplasmic reticulum (ER) localization is critical for DsbA-L protein to suppress ER stress and adiponectin down-regulation in adipocytes.Meilian Liu et al.The Journal of biological chemistry, 290(16), 10143-10148 (2015-03-06) IFI6 depletion inhibits esophageal squamous cell carcinoma progression through reactive oxygen species accumulation via mitochondrial dysfunction and endoplasmic reticulum stress.Zhenchuan Liu et al.Journal of experimental & clinical cancer research : CR, 39(1), 144-144 (2020-07-31) pERp1 is significantly up-regulated during plasma cell differentiation and contributes to the oxidative folding of immunoglobulin.Yuichiro Shimizu et al.Proceedings of the National Academy of Sciences of the United States of America, 106(40), 17013-17018 (2009-10-07) Formation of precisely composed cancer cell clusters using a cell assembly generator (CAGE) for studying paracrine signaling at single-cell resolution.Nikos Fatsis-Kavalopoulos et al.Lab on a chip, 19(6), 1071-1081 (2019-02-21) A novel HDAC6 inhibitor Tubastatin A: Controls HDAC6-p97/VCP-mediated ubiquitination-autophagy turnover and reverses Temozolomide-induced ER stress-tolerance in GBM cells.Zong-Yang Li et al.Cancer letters, 391, 89-99 (2017-01-31) Bile Acids Do Not Contribute to the Altered Calcium Homeostasis of Platelets from Rats with Biliary Cirrhosis.Paola Romecín et al.Frontiers in physiology, 8, 384-384 (2017-06-24) Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection.Nandan S Gokhale et al.Molecular cell, 77(3), 542-555 (2019-12-08) Anti-Cancer Effect of Cap-Translation Inhibitor 4EGI-1 in Human Glioma U87 Cells: Involvement of Mitochondrial Dysfunction and ER Stress.Ming Wu et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 40(5), 1013-1028 (2016-12-13) Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy.Naoki Okumura et al.Investigative ophthalmology & visual science, 58(9), 3697-3707 (2017-07-21) Interplay between the oxidoreductase PDIA6 and microRNA-322 controls the response to disrupted endoplasmic reticulum calcium homeostasis.Jody Groenendyk et al.Science signaling, 7(329), ra54-ra54 (2014-06-12) Sulfonyl(thio)urea derivative induction of insulin secretion is mediated by potassium, calcium, and sodium channel signal transduction.Paola Miranda Sulis et al.Journal of cellular physiology, 234(7), 10138-10147 (2018-11-13) Regulation of cardiac myocyte cohesion and gap junctions via desmosomal adhesion.Camilla Schinner et al.Acta physiologica (Oxford, England), 226(2), e13242-e13242 (2018-12-26) Clinical, histological and genetic characterisation of patients with tubular aggregate myopathy caused by mutations in STIM1.Johann Böhm et al.Journal of medical genetics, 51(12), 824-833 (2014-10-19) Evidence that nitric oxide is a non-adrenergic non-cholinergic inhibitory neurotransmitter in the circular muscle of the mouse distal colon: a study on the mechanism of nitric oxide-induced relaxation.Kazuhiro Nishiyama et al.Pharmacology, 94(3-4), 99-108 (2014-09-18) Centrosome Amplification in Cancer Disrupts Autophagy and Sensitizes to Autophagy Inhibition.Ryan A Denu et al.Molecular cancer research : MCR, 18(1), 33-45 (2019-10-13) Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2.Jing Deng et al.Molecular and cellular biology, 24(23), 10161-10168 (2004-11-16) Hormone regulates endometrial function via cooperation of endoplasmic reticulum stress and mTOR-autophagy.Diqi Yang et al.Journal of cellular physiology, 233(9), 6644-6659 (2017-12-06) ER stress attenuation by Aloe-derived polysaccharides in the protection of pancreatic β-cells from free fatty acid-induced lipotoxicity.Kisoo Kim et al.Biochemical and biophysical research communications, 500(3), 797-803 (2018-04-24) Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy.Yi-Fan Chen et al.Scientific reports, 7, 45366-45366 (2017-03-30) Inhibition of clathrin-mediated endocytosis prevents amyloid β-induced axonal damage.Tomoharu Kuboyama et al.Neurobiology of aging, 36(5), 1808-1819 (2015-03-17) Leptin-Induced Endothelium-Independent Vasoconstriction in Thoracic Aorta and Pulmonary Artery of Spontaneously Hypertensive Rats: Role of Calcium Channels and Stores.Samantha Gomart et al.PloS one, 12(1), e0169205-e0169205 (2017-01-14) Induction of Autophagic Death of Human Hepatocellular Carcinoma Cells by Armillaridin from Armillaria mellea.Yi-Shing Leu et al.The American journal of Chinese medicine, 47(6), 1365-1380 (2019-09-07) The Cation Channel TMEM63B Is an Osmosensor Required for Hearing.Han Du et al.Cell reports, 31(5), 107596-107596 (2020-05-07) JNK and ATF4 as two important platforms for tumor necrosis factor-α-stimulated shedding of receptor for advanced glycation end products.Akio Miyoshi et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(3), 3575-3589 (2018-11-20) T Cell Subset and Stimulation Strength-Dependent Modulation of T Cell Activation by Kv1.3 Blockers.Wai-Ping Fung-Leung et al.PloS one, 12(1), e0170102-e0170102 (2017-01-21) Carbon Monoxide, a Retrograde Messenger Generated in Postsynaptic Mushroom Body Neurons, Evokes Noncanonical Dopamine Release.Kohei Ueno et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(18), 3533-3548 (2020-04-08) A Unique ISR Program Determines Cellular Responses to Chronic Stress.Bo-Jhih Guan et al.Molecular cell, 68(5), 885-900 (2017-12-09) Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism.Takayoshi Sasako et al.Nature communications, 10(1), 947-947 (2019-03-01) TRAPPC13 modulates autophagy and the response to Golgi stress.Silvia Ramírez-Peinado et al.Journal of cell science, 130(14), 2251-2265 (2017-05-26) Agonist-dependent modulation of cell surface expression of the cold receptor TRPM8.Carlos A Toro et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(2), 571-582 (2015-01-16) Induction of Herpud1 expression by ER stress is regulated by Nrf1.Daniel V Ho et al.FEBS letters, 589(5), 615-620 (2015-02-01) The sarcoplasmic reticulum Ca2+ pump: inhibition by thapsigargin and enhancement by adenovirus-mediated gene transfer.G Inesi et al.Annals of the New York Academy of Sciences, 853, 195-206 (1999-12-22) Signaling involved in PTTH-stimulated 4E-BP phosphorylation in prothoracic gland cells of Bombyx mori.Shi-Hong Gu et al.Journal of insect physiology, 96, 1-8 (2016-11-05) Carbon Monoxide, a Retrograde Messenger Generated in Postsynaptic Mushroom Body Neurons, Evokes Noncanonical Dopamine Release.Kohei Ueno et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(18), 3533-3548 (2020-04-08) A Unique ISR Program Determines Cellular Responses to Chronic Stress.Bo-Jhih Guan et al.Molecular cell, 68(5), 885-900 (2017-12-09) Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism.Takayoshi Sasako et al.Nature communications, 10(1), 947-947 (2019-03-01) TRAPPC13 modulates autophagy and the response to Golgi stress.Silvia Ramírez-Peinado et al.Journal of cell science, 130(14), 2251-2265 (2017-05-26) The Human Cytomegalovirus Endoplasmic Reticulum-Resident Glycoprotein UL148 Activates the Unfolded Protein Response.Mohammed N A Siddiquey et al.Journal of virology, 92(20) (2018-07-27) Endoplasmic Reticulum Stress Affects Lipid Metabolism in Atherosclerosis Via CHOP Activation and Over-Expression of miR-33.Yan Sun et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 48(5), 1995-2010 (2018-08-10) NFAT1 promotes intratumoral neutrophil infiltration by regulating IL8 expression in breast cancer.Aura Kaunisto et al.Molecular oncology, 9(6), 1140-1154 (2015-03-05) Chondroprotective effects of Salubrinal in a mouse model of osteoarthritis.K Hamamura et al.Bone & joint research, 4(5), 84-92 (2015-05-16) HIF-1α metabolically controls collagen synthesis and modification in chondrocytes.Steve Stegen et al.Nature, 565(7740), 511-515 (2019-01-18) Ca2+/CaM/CaMK signaling is involved in cadmium-induced osteoclast differentiation.Wei Liu et al.Toxicology, 441, 152520-152520 (2020-06-12) Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology.Rachel H L H Rueli et al.Journal of Alzheimer's disease : JAD, 55(2), 749-762 (2016-11-02) Phosphoinositides modulate the voltage dependence of two-pore channel 3.Takushi Shimomura et al.The Journal of general physiology, 151(8), 986-1006 (2019-06-12) REDD1 enhances protein phosphatase 2A-mediated dephosphorylation of Akt to repress mTORC1 signaling.Michael D Dennis et al.Science signaling, 7(335), ra68-ra68 (2014-07-25) Fluoride exposure alters Ca2+ signaling and mitochondrial function in enamel cells.Francisco J Aulestia et al.Science signaling, 13(619) (2020-02-20) Kainate Receptor-Mediated Depression of Glutamate Release Involves Protein Kinase A in the Cerebellum.Rafael Falcón-Moya et al.International journal of molecular sciences, 20(17) (2019-08-28) Tetrahydrobenzimidazole TMQ0153 triggers apoptosis, autophagy and necroptosis crosstalk in chronic myeloid leukemia.Sungmi Song et al.Cell death & disease, 11(2), 109-109 (2020-02-09) Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy.Yi-Fan Chen et al.Scientific reports, 7, 45366-45366 (2017-03-30) Inhibition of clathrin-mediated endocytosis prevents amyloid β-induced axonal damage.Tomoharu Kuboyama et al.Neurobiology of aging, 36(5), 1808-1819 (2015-03-17) Dynein light chain 1 induces assembly of large Bim complexes on mitochondria that stabilize Mcl-1 and regulate apoptosis.Prafull Kumar Singh et al.Genes & development, 31(17), 1754-1769 (2017-10-07) Selenium Attenuates Chronic Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in Mouse Granulosa Cells.Yongjie Xiong et al.Molecules (Basel, Switzerland), 25(3) (2020-02-06) The Cation Channel TMEM63B Is an Osmosensor Required for Hearing.Han Du et al.Cell reports, 31(5), 107596-107596 (2020-05-07) JNK and ATF4 as two important platforms for tumor necrosis factor-α-stimulated shedding of receptor for advanced glycation end products.Akio Miyoshi et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(3), 3575-3589 (2018-11-20) Leptin-Induced Endothelium-Independent Vasoconstriction in Thoracic Aorta and Pulmonary Artery of Spontaneously Hypertensive Rats: Role of Calcium Channels and Stores.Samantha Gomart et al.PloS one, 12(1), e0169205-e0169205 (2017-01-14) Induction of Autophagic Death of Human Hepatocellular Carcinoma Cells by Armillaridin from Armillaria mellea.Yi-Shing Leu et al.The American journal of Chinese medicine, 47(6), 1365-1380 (2019-09-07) Turning off of GluN2B subunits and turning on of CICR in hippocampal LTD induction after developmental GluN2 subunit switch.Hiroki Yasuda et al.Hippocampus, 25(11), 1274-1284 (2015-03-03) Yhhu4488, a novel GPR40 agonist, promotes GLP-1 secretion and exerts anti-diabetic effect in rodent models.Dan-yang Guo et al.Biochemical and biophysical research communications, 466(4), 740-747 (2015-09-30) A potential new approach for treating systemic sclerosis: Dedifferentiation of SSc fibroblasts and change in the microenvironment by blocking store-operated Ca2+ entry.Ching-Ying Wu et al.PloS one, 14(3), e0213400-e0213400 (2019-03-15) Kaempferol induces autophagic cell death via IRE1-JNK-CHOP pathway and inhibition of G9a in gastric cancer cells.Tae Woo Kim et al.Cell death & disease, 9(9), 875-875 (2018-08-31) Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity.Samuel M Gonçalves et al.Nature communications, 11(1), 2282-2282 (2020-05-10) FKBP9 promotes the malignant behavior of glioblastoma cells and confers resistance to endoplasmic reticulum stress inducers.Huizhe Xu et al.Journal of experimental & clinical cancer research : CR, 39(1), 44-44 (2020-03-01) Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity.Chu-Xiao Liu et al.Cell, 177(4), 865-880 (2019-04-30) Signaling and functional competency of neutrophils derived from bone-marrow cells expressing the ER-HOXB8 oncoprotein.Stephanie Saul et al.Journal of leukocyte biology, 106(5), 1101-1115 (2019-06-20) Rapid induction of p62 and GABARAPL1 upon proteasome inhibition promotes survival before autophagy activation.Zhe Sha et al.The Journal of cell biology, 217(5), 1757-1776 (2018-03-15) Calcium signaling and the novel anti-proliferative effect of the UTP-sensitive P2Y11 receptor in rat cardiac myofibroblasts.Mariana Certal et al.Cell calcium, 58(5), 518-533 (2015-09-02) Signaling Through Purinergic Receptor P2Y2 Enhances Macrophage IL-1β Production.Gonzalo de la Rosa et al.International journal of molecular sciences, 21(13) (2020-07-08) Regulation of store-operated Ca2+ entry activity by cell cycle dependent up-regulation of Orai2 in brain capillary endothelial cells.Hiroaki Kito et al.Biochemical and biophysical research communications, 459(3), 457-462 (2015-03-10) Activation of protein kinase R in the manganese-induced apoptosis of PC12 cells.Kazuya Yagyu et al.Toxicology, 442, 152526-152526 (2020-06-24) An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure.Yoshinori Takahashi et al.Nature communications, 9(1), 2855-2855 (2018-07-22) Local pulsatile contractions are an intrinsic property of the myosin 2A motor in the cortical cytoskeleton of adherent cells.Michelle A Baird et al.Molecular biology of the cell, 28(2), 240-251 (2016-11-25) Mechanical stretch triggers rapid epithelial cell division through Piezo1.S A Gudipaty et al.Nature, 543(7643), 118-121 (2017-02-16) Endoplasmic Reticulum Stress Affects Lipid Metabolism in Atherosclerosis Via CHOP Activation and Over-Expression of miR-33.Yan Sun et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 48(5), 1995-2010 (2018-08-10) NFAT1 promotes intratumoral neutrophil infiltration by regulating IL8 expression in breast cancer.Aura Kaunisto et al.Molecular oncology, 9(6), 1140-1154 (2015-03-05) STIM1 regulates TRPC6 heteromultimerization and subcellular location.Letizia Albarrán et al.The Biochemical journal, 463(3), 373-381 (2014-08-05) Endoplasmic Reticulum Stress Response of Trabecular Meshwork Stem Cells and Trabecular Meshwork Cells and Protective Effects of Activated PERK Pathway.Yiwen Wang et al.Investigative ophthalmology & visual science, 60(1), 265-273 (2019-01-18) Tauroursodeoxycholic Acid Alleviates H2O2-Induced Oxidative Stress and Apoptosis via Suppressing Endoplasmic Reticulum Stress in Neonatal Rat Cardiomyocytes.Lin Zhang et al.Dose-response : a publication of International Hormesis Society, 16(3), 1559325818782631-1559325818782631 (2018-07-25) CMT-linked loss-of-function mutations in GDAP1 impair store-operated CaPaloma González-Sánchez et al.Scientific reports, 7, 42993-42993 (2017-02-22) Heparanase protects the heart against chemical or ischemia/reperfusion injury.Fulong Wang et al.Journal of molecular and cellular cardiology, 131, 29-40 (2019-04-21) Regulation of Adipsin Expression by Endoplasmic Reticulum Stress in Adipocytes.Ka-Young Ryu et al.Biomolecules, 10(2) (2020-02-23) De-differentiation confers multidrug resistance via noncanonical PERK-Nrf2 signaling.Catherine A Del Vecchio et al.PLoS biology, 12(9), e1001945-e1001945 (2014-09-10) Phosphate-induced ORAI1 expression and store-operated Ca2+ entry in aortic smooth muscle cells.Ke Ma et al.Journal of molecular medicine (Berlin, Germany), 97(10), 1465-1475 (2019-08-07) Prostaglandin EEmily J A Taylor et al.Molecular pharmacology, 92(5), 533-545 (2017-09-08) 5-Azacytidine engages an IRE1α-EGFR-ERK1/2 signaling pathway that stabilizes the LDL receptor mRNA.Nourhen Mnasri et al.Biochimica et biophysica acta, 1861(1), 29-40 (2017-12-07) TGF-β1 Activates Nasal Fibroblasts through the Induction of Endoplasmic Reticulum Stress.Jae-Min Shin et al.Biomolecules, 10(6) (2020-06-26) Development of a fluorescent reporter system for monitoring ER stress in Chinese hamster ovary cells and its application for therapeutic protein production.Gargi Roy et al.PloS one, 12(8), e0183694-e0183694 (2017-08-24) 4-Phenylbutyrate attenuates the ER stress response and cyclic AMP accumulation in DYT1 dystonia cell models.Jin A Cho et al.PloS one, 9(11), e110086-e110086 (2014-11-08) SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response.Huimin Liu et al.Cell death & disease, 11(6), 445-445 (2020-06-12) Prostaglandin EEmily J A Taylor et al.Molecular pharmacology, 92(5), 533-545 (2017-09-08) 5-Azacytidine engages an IRE1α-EGFR-ERK1/2 signaling pathway that stabilizes the LDL receptor mRNA.Nourhen Mnasri et al.Biochimica et biophysica acta, 1861(1), 29-40 (2017-12-07) Paeoniflorin prevents endoplasmic reticulum stress-associated inflammation in lipopolysaccharide-stimulated human umbilical vein endothelial cells via the IRE1α/NF-κB signaling pathway.Juan Chen et al.Food & function, 9(4), 2386-2397 (2018-03-30) Mechanism underlying N-(3-oxo-dodecanoyl)-L-homoserine lactone mediated intracellular calcium mobilization in human platelets.Vivek Kumar Yadav et al.Blood cells, molecules & diseases, 79, 102340-102340 (2019-06-18) In vitro study of carbon black nanoparticles on human pulmonary artery endothelial cells: effects on calcium signaling and mitochondrial alterations.J Deweirdt et al.Archives of toxicology, 94(7), 2331-2348 (2020-05-13) Chrysin Ameliorates Malfunction of Retinoid Visual Cycle through Blocking Activation of AGE-RAGE-ER Stress in Glucose-Stimulated Retinal Pigment Epithelial Cells and Diabetic Eyes.Min-Kyung Kang et al.Nutrients, 10(8) (2018-08-12) Inhibition of double-stranded RNA-dependent protein kinase prevents oxytosis and ferroptosis in mouse hippocampal HT22 cells.Yoko Hirata et al.Toxicology, 418, 1-10 (2019-03-01) Vildagliptin, an Anti-diabetic Drug of the DPP-4 Inhibitor, Induces Vasodilation via Kv Channel and SERCA Pump Activation in Aortic Smooth Muscle.Mi Seon Seo et al.Cardiovascular toxicology, 19(3), 244-254 (2018-12-07) Effect of oleic acid on store-operated calcium entry in immune-competent cells.Celia Carrillo et al.European journal of nutrition, 56(3), 1077-1084 (2016-02-03) Exendin-4 attenuates high glucose-induced cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and activation of SERCA2a.Craig W Younce et al.American journal of physiology. Cell physiology, 304(6), C508-C518 (2013-01-11) Structure and mechanism of the mitochondrial Ca2+ uniporter holocomplex.Minrui Fan et al.Nature, 582(7810), 129-133 (2020-06-05) Targeting interleukin-20 alleviates paclitaxel-induced peripheral neuropathy.Li-Hsien Chen et al.Pain, 161(6), 1237-1254 (2020-02-19) Calcitonin Peptide Family Members Are Differentially Regulated by LPS and Inhibit Functions of Rat Alveolar NR8383 Macrophages.Aichurek Soultanova et al.PloS one, 11(10), e0163483-e0163483 (2016-10-14) Tumor suppressor BTG1 promotes PRMT1-mediated ATF4 function in response to cellular stress.Laurensia Yuniati et al.Oncotarget, 7(3), 3128-3143 (2015-12-15) The Impact of Vitamin D3 Supplementation on Mechanisms of Cell Calcium Signaling in Chronic Kidney Disease.Ingrid Lajdova et al.BioMed research international, 2015, 807673-807673 (2015-06-13) Role of ZnS Nanoparticles on Endoplasmic Reticulum Stress-mediated Apoptosis in Retinal Pigment Epithelial Cells.Bose Karthikeyan et al.Biological trace element research, 170(2), 390-400 (2015-09-04) Mitochondrial Ca2+ removal amplifies TRAIL cytotoxicity toward apoptosis-resistant tumor cells via promotion of multiple cell death modalities.Natsuhiko Takata et al.International journal of oncology, 51(1), 193-203 (2017-06-01) TRPV2 channels mediate insulin secretion induced by cell swelling in mouse pancreatic β-cells.Toshiaki Sawatani et al.American journal of physiology. Cell physiology, 316(3), C434-C443 (2019-01-17) The Traditional Medicine Banhasasim-Tang Depolarizes Pacemaker Potentials of Cultured Interstitial Cells of Cajal through M3 Muscarinic and 5-HT3 Receptors in Murine Small Intestine.Jeong Nam Kim et al.Digestion, 101(5), 536-551 (2019-06-12) GSK2656157, a PERK inhibitor, reduced LPS-induced IL-1β production through inhibiting Caspase 1 activation in macrophage-like J774.1 cells.Takashi Ando et al.Immunopharmacology and immunotoxicology, 38(4), 298-302 (2016-06-03) Partially Defective Store Operated Calcium Entry and Hem(ITAM) Signaling in Platelets of Serotonin Transporter Deficient Mice.Karen Wolf et al.PloS one, 11(1), e0147664-e0147664 (2016-01-23) An initial phase of JNK activation inhibits cell death early in the endoplasmic reticulum stress response.Max Brown et al.Journal of cell science, 129(12), 2317-2328 (2016-04-29) Assembly of the Elongin A Ubiquitin Ligase Is Regulated by Genotoxic and Other Stresses.Juston C Weems et al.The Journal of biological chemistry, 290(24), 15030-15041 (2015-04-17) Ca2+ mobilization-dependent reduction of the endoplasmic reticulum lumen is due to influx of cytosolic glutathione.Beáta Lizák et al.BMC biology, 18(1), 19-19 (2020-02-27) The vasodilatory effect of gemigliptin via activation of voltage-dependent K+ channels and SERCA pumps in aortic smooth muscle.Hee Seok Jung et al.European journal of pharmacology, 882, 173243-173243 (2020-06-15) Cellular stress induces TRB3/USP9x-dependent Notch activation in cancer.J Izrailit et al.Oncogene, 36(8), 1048-1057 (2016-09-07) Screening Mycobacterium tuberculosis Secreted Proteins Identifies Mpt64 as a Eukaryotic Membrane-Binding Bacterial Effector.Chelsea E Stamm et al.mSphere, 4(3) (2019-06-07) Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components.Paula Lindner et al.Cell communication and signaling : CCS, 18(1), 12-12 (2020-01-29) Calcium homeostasis is altered in skeletal muscle of spontaneously hypertensive rats: cytofluorimetric and gene expression analysis.Antonella Liantonio et al.The American journal of pathology, 184(10), 2803-2815 (2014-08-02) Tyrosine phosphorylation directs TACE into extracellular vesicles via unconventional secretion.Zhe Zhao et al.Traffic (Copenhagen, Denmark), 20(3), 202-212 (2018-12-21) Migration and Phagocytic Ability of Activated Microglia During Post-natal Development is Mediated by Calcium-Dependent Purinergic Signalling.Aditya Sunkaria et al.Molecular neurobiology, 53(2), 944-954 (2015-01-13) Endo-lysosomal TRP mucolipin-1 channels trigger global ER Ca2+ release and Ca2+ influx.Bethan S Kilpatrick et al.Journal of cell science, 129(20), 3859-3867 (2016-09-01) Induction of endoplasmic reticulum-derived oxidative stress by an occult infection related S surface antigen variant.In-Kyung Lee et al.World journal of gastroenterology, 21(22), 6872-6883 (2015-06-17) Sphingosine-1-phosphate-activated TRPC1 channel controls chemotaxis of glioblastoma cells.Sophie Lepannetier et al.Cell calcium, 60(6), 373-383 (2016-09-18) Stress of endoplasmic reticulum modulates differentiation and lipogenesis of human adipocytes.Michal Koc et al.Biochemical and biophysical research communications, 460(3), 684-690 (2015-03-31) Possible association of CAG repeat polymorphism in KCNN3 encoding the potassium channel SK3 with oxaliplatin-induced neurotoxicity.Benjamin Anon et al.Cancer chemotherapy and pharmacology, 82(1), 149-157 (2018-05-19) mTOR inhibitors activate PERK signaling and favor viability of gastrointestinal neuroendocrine cell lines.Patricia Freis et al.Oncotarget, 8(13), 20974-20987 (2017-04-21) Inhibition of the PI 3-kinase pathway disrupts the unfolded protein response and reduces sensitivity to ER stress-dependent apoptosis.Jonathon N Winnay et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(9), 12521-12532 (2020-08-04) Autophagy blockade and lysosomal membrane permeabilization contribute to lead-induced nephrotoxicity in primary rat proximal tubular cells.Xiang-Bin Song et al.Cell death & disease, 8(6), e2863-e2863 (2017-06-09) Saber Tadros et al.Cancer research, 77(20), 5503-5517 (2017-08-16)Pancreatic adenocarcinoma is moderately responsive to gemcitabine-based chemotherapy, the most widely used single-agent therapy for pancreatic cancer. Although the prognosis in pancreatic cancer remains grim in part due to poor response to therapy, previous attempts at identifying and targeting the... RGS2 promotes the translation of stress-associated proteins ATF4 and CHOP via its eIF2B-inhibitory domain.Chang-Hui Jenny Wang et al.Cellular signalling, 59, 163-170 (2019-03-04) Antihypertrophic Effects of Small Molecules that Maintain Mitochondrial ATP Levels Under Hypoxia.Hiroaki Nagai et al.EBioMedicine, 24, 147-158 (2017-09-25) Pre-malignant transformation by senescence evasion is prevented by the PERK and ATF6alpha branches of the Unfolded Protein Response.Claire Drullion et al.Cancer letters, 438, 187-196 (2018-09-15) H2A Monoubiquitination Links Glucose Availability to Epigenetic Regulation of the Endoplasmic Reticulum Stress Response and Cancer Cell Death.Yilei Zhang et al.Cancer research, 80(11), 2243-2256 (2020-04-11) Photodynamic therapy with redaporfin targets the endoplasmic reticulum and Golgi apparatus.Lígia C Gomes-da-Silva et al.The EMBO journal, 37(13) (2018-05-29) The Integrated Stress Response Regulates Cell Health of Cardiac Progenitors.George H Searfoss et al.Toxicological sciences : an official journal of the Society of Toxicology, 167(1), 202-210 (2018-09-15) Pancreatic stone protein/regenerating protein is a potential biomarker for endoplasmic reticulum stress in beta cells.Stephen Stone et al.Scientific reports, 9(1), 5199-5199 (2019-03-28) Preliminary Structure-Activity Relationship (SAR) of a Novel Series of Pyrazole SKF-96365 Analogues as Potential Store-Operated Calcium Entry (SOCE) Inhibitors.Camille D Dago et al.International journal of molecular sciences, 19(3) (2018-03-15) Unfolded protein response-induced dysregulation of calcium homeostasis promotes retinal degeneration in rat models of autosomal dominant retinitis pigmentosa.V Shinde et al.Cell death & disease, 7, e2085-e2085 (2016-02-06) Calcium Uptake via Mitochondrial Uniporter Contributes to Palmitic Acid-Induced Apoptosis in Mouse Podocytes.Zeting Yuan et al.Journal of cellular biochemistry, 118(9), 2809-2818 (2017-02-10) Digitoxin enhances the growth inhibitory effects of thapsigargin and simvastatin on ER negative human breast cancer cells.Linda Saxe Einbond et al.Fitoterapia, 109, 146-154 (2015-12-23) Neuronal Store-Operated Calcium Entry and Mushroom Spine Loss in Amyloid Precursor Protein Knock-In Mouse Model of Alzheimer's Disease.Hua Zhang et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(39), 13275-13286 (2015-10-02) Structural basis of astrocytic Ca2+ signals at tripartite synapses.Misa Arizono et al.Nature communications, 11(1), 1906-1906 (2020-04-22) Generation and characterization of an analog-sensitive PERK allele.Nancy L Maas et al.Cancer biology & therapy, 15(8), 1106-1111 (2014-05-23) Cortical actin contributes to spatial organization of ER-PM junctions.Ting-Sung Hsieh et al.Molecular biology of the cell, 28(23), 3171-3180 (2017-09-29) Chloroquine inhibits CaYi-Fan Wu et al.Cell & bioscience, 7, 28-28 (2017-05-27) Glucocorticoids Prevent Enterovirus 71 Capsid Protein VP1 Induced Calreticulin Surface Exposure by Alleviating Neuronal ER Stress.Dan-Dan Hu et al.Neurotoxicity research, 31(2), 204-217 (2016-11-17) Ophiopogonin D maintains Ca2+ homeostasis in rat cardiomyocytes in vitro by upregulating CYP2J3/EETs and suppressing ER stress.Wen-ting You et al.Acta pharmacologica Sinica, 37(3), 368-381 (2016-02-04) Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts.Marina Sokolova et al.Biochimica et biophysica acta, 1862(2), 234-245 (2016-11-16) The role of calcium signalling in the chondrogenic response of mesenchymal stem cells to hydrostatic pressure.A J Steward et al.European cells & materials, 28, 358-371 (2014-10-29) Misfolded proteins bind and activate death receptor 5 to trigger apoptosis during unresolved endoplasmic reticulum stress.Mable Lam et al.eLife, 9 (2020-01-07) Elucidating post-translational regulation of mouse CREB3 in Neuro2a cells.Kentaro Oh-Hashi et al.Molecular and cellular biochemistry, 448(1-2), 287-297 (2018-02-20) Inhibition of the hexosamine biosynthesis pathway potentiates cisplatin cytotoxicity by decreasing BiP expression in non-small-cell lung cancer cells.Wenshu Chen et al.Molecular carcinogenesis, 58(6), 1046-1055 (2019-02-23) Translation without eIF2 promoted by poliovirus 2A protease.Natalia Redondo et al.PloS one, 6(10), e25699-e25699 (2011-10-18) A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis.Steven M Moss et al.Cell host & microbe, 25(3), 454-462 (2019-03-05) High-frequency sarcomeric auto-oscillations induced by heating in living neonatal cardiomyocytes of the rat.Seine A Shintani et al.Biochemical and biophysical research communications, 457(2), 165-170 (2014-12-30) Biological activity and apoptotic signaling pathway of C11-functionalized cephalostatin 1 analogues.Mansour M Nawasreh et al.Steroids, 158, 108602-108602 (2020-02-25) An NFκB Activity Calculator to Delineate Signaling Crosstalk: Type I and II Interferons Enhance NFκB via Distinct Mechanisms.Simon Mitchell et al.Frontiers in immunology, 10, 1425-1425 (2019-07-12) Myosin light chain kinase controls voltage-dependent calcium channels in vascular smooth muscle.A Martinsen et al.Pflugers Archiv : European journal of physiology, 466(7), 1377-1389 (2013-10-29) The KSR2-calcineurin complex regulates STIM1-ORAI1 dynamics and store-operated calcium entry (SOCE).E Giurisato et al.Molecular biology of the cell, 25(11), 1769-1781 (2014-03-29) Calcium sequestration by fungal melanin inhibits calcium-calmodulin signalling to prevent LC3-associated phagocytosis.Irene Kyrmizi et al.Nature microbiology, 3(7), 791-803 (2018-06-01) Hsp90 inhibition by PU-H71 induces apoptosis through endoplasmic reticulum stress and mitochondrial pathway in cancer cells and overcomes the resistance conferred by Bcl-2.Cindy Gallerne et al.Biochimica et biophysica acta, 1833(6), 1356-1366 (2013-03-15) The Calreticulin control of human stress erythropoiesis is impaired by JAK2V617F in polycythemia vera.Mario Falchi et al.Experimental hematology, 50, 53-76 (2017-02-25) Altered Intracellular Calcium Homeostasis Underlying Enhanced Glutamatergic Transmission in Striatal-Enriched Tyrosine Phosphatase (STEP) Knockout Mice.Federica Bosco et al.Molecular neurobiology, 55(10), 8084-8102 (2018-03-07) PCAF interacts with XBP-1S and mediates XBP-1S-dependent transcription.Qiao Jing Lew et al.Nucleic acids research, 39(2), 429-439 (2010-09-08) Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release.Chuchu Zhang et al.Proceedings of the National Academy of Sciences of the United States of America, 114(12), E2524-E2532 (2017-03-08) Impact of the Reticular Stress and Unfolded Protein Response on the inflammatory response in endometrial stromal cells.E Grasso et al.Scientific reports, 8(1), 12274-12274 (2018-08-18) Nitric oxide promotes GABA release by activating a voltage-independent CaJ Wesley Maddox et al.Journal of neurophysiology, 117(3), 1185-1199 (2017-01-06) Ca(2+)-mediated regulation of VDAC1 expression levels is associated with cell death induction.Shira Weisthal et al.Biochimica et biophysica acta, 1843(10), 2270-2281 (2014-04-08) The vasodilatory effect of the antidiabetic drug linagliptin via inhibition of Rho-associated protein kinase in aortic smooth muscle.Mi Seon Seo et al.Life sciences, 219, 1-10 (2019-01-09) The polyphenol ellagic acid exerts anti-inflammatory actions via disruption of store-operated calcium entry (SOCE) pathway activators and coupling mediators.Matthew T Murphy et al.European journal of pharmacology, 875, 173036-173036 (2020-02-27) Calreticulin Ins5 and Del52 mutations impair unfolded protein and oxidative stress responses in K562 cells expressing CALR mutants.Simona Salati et al.Scientific reports, 9(1), 10558-10558 (2019-07-25) Photoactivated fullerene C60 induces store-operated Ca2 entry and cytochrome c release in Jurkat cells.S M Grebinyk et al.Ukrains'kyi biokhimichnyi zhurnal (1999 ), 84(6), 58-63 (2013-02-08) Polyunsaturated fatty acids inhibit stimulated coupling between the ER Ca(2+) sensor STIM1 and the Ca(2+) channel protein Orai1 in a process that correlates with inhibition of stimulated STIM1 oligomerization.David Holowka et al.Biochimica et biophysica acta, 1841(8), 1210-1216 (2014-04-29) Trans-4-methoxy-β-nitrostyrene relaxes rat thoracic aorta through a sGC-dependent pathway.Loeste Arruda-Barbosa et al.European journal of pharmacology, 807, 182-189 (2017-05-10) IP3R-Mediated Compensatory Mechanism for Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Cardiac Ryanodine Receptor Deficiency.Xiaojing Luo et al.Frontiers in cell and developmental biology, 8, 772-772 (2020-09-10) GIV/Girdin promotes cell survival during endoplasmic reticulum stress.Peter Nguyen et al.Molecular and cellular biochemistry, 453(1-2), 79-88 (2018-08-27) Cutting Edge: identification of neutrophil PGLYRP1 as a ligand for TREM-1.Christine B Read et al.Journal of immunology (Baltimore, Md. : 1950), 194(4), 1417-1421 (2015-01-18) Acetaldehyde suppresses HBV-MHC class I complex presentation on hepatocytes via induction of ER stress and Golgi fragmentation.Murali Ganesan et al.American journal of physiology. Gastrointestinal and liver physiology, 319(4), G432-G442 (2020-08-07) Aspirin metabolite sodium salicylate selectively inhibits transcriptional activity of ATF6α and downstream target genes.Fernanda L B Mügge et al.Scientific reports, 7(1), 9190-9190 (2017-08-25) Effects of PERK eIF2α Kinase Inhibitor against Toxoplasma gondii.Leonardo Augusto et al.Antimicrobial agents and chemotherapy, 62(11) (2018-09-06) Imaging of mitochondrial and non-mitochondrial responses in cultured rat hippocampal neurons exposed to micromolar concentrations of TMRM.Andrew Monteith et al.PloS one, 8(3), e58059-e58059 (2013-03-14) Mechanisms underlying the vasorelaxant effect of trans-4-methoxy-β-nitrostyrene in the rat mesenteric resistance arteries.Thayane Rebeca Alves-Santos et al.European journal of pharmacology, 853, 201-209 (2019-02-05) Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphocytes.Shanique K E Edwards et al.Journal of hematology & oncology, 7, 56-56 (2014-09-10) Regulation of proto-oncogene Orai3 by miR18a/b and miR34a.Ayushi Vashisht et al.Cell calcium, 75, 101-111 (2018-09-15) G-protein inhibition profile of the reported Gq/11 inhibitor UBO-QIC.Jyrki P Kukkonen Biochemical and biophysical research communications, 469(1), 101-107 (2015-11-29) The mammalian STE20-like kinase 1 (MST1) is a substrate for the apoptosis inhibiting protein kinase CK2.Christina Servas et al.Cellular signalling, 36, 163-175 (2017-05-11) Lung immunoglobulin A immunity dysregulation in cystic fibrosis.Amandine M Collin et al.EBioMedicine, 60, 102974-102974 (2020-09-15) Thapsigargin induces apoptosis when autophagy is inhibited in HepG2 cells and both processes are regulated by ROS-dependent pathway.Congcong Wang et al.Environmental toxicology and pharmacology, 41, 167-179 (2015-12-29) Trisk 95 as a novel skin mirror for normal and diabetic systemic glucose level.Nsrein Ali et al.Scientific reports, 10(1), 12246-12246 (2020-07-24) No evidence for cell-to-cell transmission of the unfolded protein response in cell culture.Anna M van Ziel et al.Journal of neurochemistry, 152(2), 208-220 (2019-08-24) The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport.Maria L Torgersen et al.Oncotarget, 7(52), 86871-86888 (2016-11-29) Myocardial MMP-2 contributes to SERCA2a proteolysis during cardiac ischaemia-reperfusion injury.Andrej Roczkowsky et al.Cardiovascular research, 116(5), 1021-1031 (2019-08-03) Activation of TRPV1 channel antagonizes diabetic nephropathy through inhibiting endoplasmic reticulum-mitochondria contact in podocytes.Xiao Wei et al.Metabolism: clinical and experimental, 105, 154182-154182 (2020-02-18) Cytoskeletal Protein 4.1R Is a Positive Regulator of the FcεRI Signaling and Chemotaxis in Mast Cells.Lubica Draberova et al.Frontiers in immunology, 10, 3068-3068 (2020-01-30) Sodium-glucose cotransporter 2 inhibitors regulate ketone body metabolism via inter-organ crosstalk.Jin Hee Kim et al.Diabetes, obesity & metabolism (2018-11-09) Lithium Sensitivity of Store Operated Ca2+ Entry and Survival of Fibroblasts Isolated from Chorea-Acanthocytosis Patients.Lisann Pelzl et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 42(5), 2066-2077 (2017-08-15) C/EBP-β Is Differentially Affected by PPARα Agonists Fenofibric Acid and GW7647, But Does Not Change Apolipoprotein A-I Production During ER-Stress and Inflammation.Sophie E van der Krieken et al.Journal of cellular biochemistry, 118(4), 754-763 (2016-09-13) Chemical genetics reveals a complex functional ground state of neural stem cells.Phedias Diamandis et al.Nature chemical biology, 3(5), 268-273 (2007-04-10) Ca2+ signalling behaviours of intramuscular interstitial cells of Cajal in the murine colon.Bernard T Drumm et al.The Journal of physiology, 597(14), 3587-3617 (2019-05-28) LETM1-Mediated KShane Austin et al.Frontiers in physiology, 8, 839-839 (2017-12-06) Amplification of human platelet activation by surface pannexin-1 channels.K A Taylor et al.Journal of thrombosis and haemostasis : JTH, 12(6), 987-998 (2014-03-25) Uncovering malathion (an organophosphate insecticide) action on Ca2+ signal transduction and investigating the effects of BAPTA-AM (a cell-permeant Ca2+ chelator) on protective responses in glial cells.Shu-Shong Hsu et al.Pesticide biochemistry and physiology, 157, 152-160 (2019-06-04) Physiologic force-frequency response in engineered heart muscle by electromechanical stimulation.Amandine F G Godier-Furnémont et al.Biomaterials, 60, 82-91 (2015-05-20) Endoplasmic reticulum protein ERp46 in prostate adenocarcinoma.Wilhelmina C M Duivenvoorden et al.Oncology letters, 13(5), 3624-3630 (2017-05-20) A novel phosphorylation by AMP-activated kinase regulates RUNX2 from ubiquitination in osteogenesis over adipogenesis.Suresh Chava et al.Cell death & disease, 9(7), 754-754 (2018-07-11) Long-term pancreatic beta cell exposure to high levels of glucose but not palmitate induces DNA methylation within the insulin gene promoter and represses transcriptional activity.Kota Ishikawa et al.PloS one, 10(2), e0115350-e0115350 (2015-02-07) Progesterone induces apoptosis of insulin-secreting cells: insights into the molecular mechanism.V A Nunes et al.The Journal of endocrinology, 221(2), 273-284 (2014-03-07) Signaling Mechanism of Cannabinoid Receptor-2 Activation-Induced β-Endorphin Release.Fang Gao et al.Molecular neurobiology, 53(6), 3616-3625 (2015-06-26) Salubrinal-Mediated Upregulation of eIF2α Phosphorylation Increases Doxorubicin Sensitivity in MCF-7/ADR Cells.Yong-Joon Jeon et al.Molecules and cells, 39(2), 129-135 (2016-01-09) Targeting Cellular Calcium Homeostasis to Prevent Cytokine-Mediated Beta Cell Death.Amy L Clark et al.Scientific reports, 7(1), 5611-5611 (2017-07-19) ATF3 modulates calcium signaling in osteoclast differentiation and activity by associating with c-Fos and NFATc1 proteins.Byung-Chul Jeong et al.Bone, 95, 33-40 (2016-11-10) Glioma-derived cancer stem cells are hypersensitive to proteasomal inhibition.Young Dong Yoo et al.EMBO reports, 18(1), 150-168 (2016-12-21) Ocular inflammation and endoplasmic reticulum stress are attenuated by supplementation with grape polyphenols in human retinal pigmented epithelium cells and in C57BL/6 mice.Jung-Heun Ha et al.The Journal of nutrition, 144(6), 799-806 (2014-04-05) Melamine induces CaAllen J Yiu et al.American journal of physiology. Cell physiology, 313(1), C27-C41 (2017-04-07) Ionomycin causes susceptibility to phospholipase A2 while temperature-induced increases in membrane fluidity fail: possible involvement of actin fragmentation.Elizabeth Gibbons et al.Biochimica et biophysica acta, 1838(10), 2607-2614 (2014-07-08) Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis.Hongtan Wu et al.Nature communications, 6, 6239-6239 (2015-02-20) Atf-6 Regulates Lifespan through ER-Mitochondrial Calcium Homeostasis.Kristopher Burkewitz et al.Cell reports, 32(10), 108125-108125 (2020-09-10) Intracellular rupture, exocytosis and actin interaction of endocytic vacuoles in pancreatic acinar cells: initiating events in acute pancreatitis.Michael Chvanov et al.The Journal of physiology, 596(13), 2547-2564 (2018-05-03) SERINC5 Inhibits the Secretion of Complete and Genome-Free Hepatitis B Virions Through Interfering With the Glycosylation of the HBV Envelope.Yue Liu et al.Frontiers in microbiology, 11, 697-697 (2020-05-21) Prolonged hypoxia delays aging and preserves functionality of human amniotic fluid stem cells.Francesca Casciaro et al.Mechanisms of ageing and development, 191, 111328-111328 (2020-08-18) Alpha-synuclein aggregates activate calcium pump SERCA leading to calcium dysregulation.Cristine Betzer et al.EMBO reports, 19(5) (2018-03-31) Moringa oleifera-rich diet and T cell calcium signaling in spontaneously hypertensive rats.E S Attakpa et al.Physiological research, 66(5), 753-767 (2017-04-14) Spiroindolones, a potent compound class for the treatment of malaria.Matthias Rottmann et al.Science (New York, N.Y.), 329(5996), 1175-1180 (2010-09-04) Calcium Regulation of Hemorrhagic Fever Virus Budding: Mechanistic Implications for Host-Oriented Therapeutic Intervention.Ziying Han et al.PLoS pathogens, 11(10), e1005220-e1005220 (2015-10-30) The E3 Ubiquitin Ligase SIAH1 Targets MyD88 for Proteasomal Degradation During Dengue Virus Infection.Ashleigh R Murphy Schafer et al.Frontiers in microbiology, 11, 24-24 (2020-03-03) Resveratrol, an activator of SIRT1, improves ER stress by increasing clusterin expression in HepG2 cells.Jinmi Lee et al.Cell stress & chaperones, 24(4), 825-833 (2019-06-12) Depolarization of pacemaker potentials by caffeic acid phenethyl ester in interstitial cells of Cajal from the murine small intestine.Jeong Nam Kim et al.Canadian journal of physiology and pharmacology, 98(4), 201-210 (2019-11-07) SOCE mediated by STIM and Orai is essential for pacemaker activity in the interstitial cells of Cajal in the gastrointestinal tract.Haifeng Zheng et al.Science signaling, 11(534) (2018-06-14) Optogenetic stimulation of phosphoinositides reveals a critical role of primary cilia in eye pressure regulation.Philipp P Prosseda et al.Science advances, 6(18), eaay8699-eaay8699 (2020-06-05) Evaluation of a dansyl-based amino acid DNSBA as an imaging probe for apoptosis detection.Min Tang et al.Apoptosis : an international journal on programmed cell death, 20(3), 410-420 (2015-01-19) Erawan Borkham-Kamphorst et al.Frontiers in pharmacology, 9, 426-426 (2018-05-15)Lipocalin 2 (LCN2) is a highly conserved secreted adipokine acting as a serum transport protein for small hydrophobic molecules such as fatty acids and steroids. In addition, LCN2 limits bacterial growth by sequestering iron-containing siderophores and further protects against intestinal... Native store-operated calcium channels are functionally expressed in mouse spinal cord dorsal horn neurons and regulate resting calcium homeostasis.Jingsheng Xia et al.The Journal of physiology, 592(16), 3443-3461 (2014-05-27) Endoplasmic reticulum stress is involved in ventilator-induced lung injury in mice via the IRE1α-TRAF2-NF-κB pathway.Liu Ye et al.International immunopharmacology, 78, 106069-106069 (2019-12-17) Inhibition of transcription by dactinomycin reveals a new characteristic of immunogenic cell stress.Juliette Humeau et al.EMBO molecular medicine, 12(5), e11622-e11622 (2020-04-24) AMP kinase promotes glioblastoma bioenergetics and tumour growth.Rishi Raj Chhipa et al.Nature cell biology, 20(7), 823-835 (2018-06-20) Shikonin, dually functions as a proteasome inhibitor and a necroptosis inducer in multiple myeloma cells.Naoko Wada et al.International journal of oncology, 46(3), 963-972 (2014-12-23) Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy.Pamela Bella et al.EMBO molecular medicine, 12(1), e11019-e11019 (2019-12-04) NHA2 promotes cyst development in an in vitro model of polycystic kidney disease.Hari Prasad et al.The Journal of physiology, 597(2), 499-519 (2018-09-23) Asymmetrical dimethylarginine induces dysfunction of insulin signal transduction via endoplasmic reticulum stress in the liver of diabetic rats.Ni Qiu et al.Life sciences, 260, 118373-118373 (2020-09-09) Anti-dsDNA antibodies induce inflammation via endoplasmic reticulum stress in human mesangial cells.Hui Zhang et al.Journal of translational medicine, 13, 178-178 (2015-06-05) A Rare UGT2B7 Variant Creates a Novel N-Glycosylation Site at Codon 121 with Impaired Enzyme Activity.Camille Girard-Bock et al.Drug metabolism and disposition: the biological fate of chemicals, 44(12), 1867-1871 (2016-10-27) An upstream open reading frame modulates ebola virus polymerase translation and virus replication.Reed S Shabman et al.PLoS pathogens, 9(1), e1003147-e1003147 (2013-02-06) Inhibition of CYP4A reduces hepatic endoplasmic reticulum stress and features of diabetes in mice.Edmond Changkyun Park et al.Gastroenterology, 147(4), 860-869 (2014-07-02) WNT16-expressing Acute Lymphoblastic Leukemia Cells are Sensitive to Autophagy Inhibitors after ER Stress Induction.Meletios Verras et al.Anticancer research, 35(9), 4625-4631 (2015-08-09) Mitofusin-2 mediated mitochondrial CaRuo-Peng Liang et al.World journal of gastroenterology, 23(38), 6995-7008 (2017-11-04) Establishment and validation of an endoplasmic reticulum stress reporter to monitor zebrafish ATF6 activity in development and disease.Eric M Clark et al.Disease models & mechanisms, 13(1) (2019-12-20) α-Lipoic acid induces Endoplasmic Reticulum stress-mediated apoptosis in hepatoma cells.Monica Pibiri et al.Scientific reports, 10(1), 7139-7139 (2020-04-30) Glucose withdrawal induces Endothelin 1 release with significant angiogenic effect from first trimester (FTM), but not term human umbilical cord perivascular cells (HUCPVC).Peter Szaraz et al.Angiogenesis, 23(2), 131-144 (2019-10-03) Berberine ameliorates lipopolysaccharide-induced acute lung injury via the PERK-mediated Nrf2/HO-1 signaling axis.Yuan Liang et al.Phytotherapy research : PTR, 33(1), 130-148 (2018-10-23) The Ca2+ sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum.Sonal Srikanth et al.Nature immunology, 20(2), 152-162 (2019-01-16) Crocin Alleviates Myocardial Ischemia/Reperfusion-Induced Endoplasmic Reticulum Stress via Regulation of miR-34a/Sirt1/Nrf2 Pathway.Xiaowu Wang et al.Shock (Augusta, Ga.), 51(1), 123-130 (2018-02-10) FoxO suppresses endoplasmic reticulum stress to inhibit growth of Tsc1-deficient tissues under nutrient restriction.Avantika Gupta et al.eLife, 9 (2020-06-12) Role of Na+/Ca2+ Exchangers in Therapy Resistance of Medulloblastoma Cells.Lisann Pelzl et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 42(3), 1240-1251 (2017-07-07) A monoclonal antibody TrkB receptor agonist as a potential therapeutic for Huntington's disease.Daniel Todd et al.PloS one, 9(2), e87923-e87923 (2014-02-08) INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division.Rajarshi Chakrabarti et al.The Journal of cell biology, 217(1), 251-268 (2017-11-17) MRGPRX4 is a G protein-coupled receptor activated by bile acids that may contribute to cholestatic pruritus.James Meixiong et al.Proceedings of the National Academy of Sciences of the United States of America, 116(21), 10525-10530 (2019-05-10) Thioesterase-mediated control of cellular calcium homeostasis enables hepatic ER stress.Baran A Ersoy et al.The Journal of clinical investigation, 128(1), 141-156 (2017-12-05) 50 years to diagnosis: Autosomal dominant tubular aggregate myopathy caused by a novel STIM1 mutation.Maggie C Walter et al.Neuromuscular disorders : NMD, 25(7), 577-584 (2015-05-09) Fast calcium wave inhibits excessive apoptosis during epithelial wound healing.Cristian Justet et al.Cell and tissue research, 365(2), 343-356 (2016-03-19) DREADD-based synthetic control of chondrocyte calcium signaling in vitro.Ryan C McDonough et al.Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 37(7), 1518-1529 (2019-03-26) FAK activates AKT-mTOR signaling to promote the growth and progression of MMTV-Wnt1-driven basal-like mammary tumors.Ritama Paul et al.Breast cancer research : BCR, 22(1), 59-59 (2020-06-05) IL13Rα1 protects against rheumatoid arthritis by combating the apoptotic resistance of fibroblast-like synoviocytes.Xiaomei Yang et al.Arthritis research & therapy, 22(1), 184-184 (2020-08-11) Luman recruiting factor regulates endoplasmic reticulum stress in mouse ovarian granulosa cell apoptosis.Yanzhou Yang et al.Theriogenology, 79(4), 633-639 (2012-12-29) BAG2 ameliorates endoplasmic reticulum stress-induced cell apoptosis in Mycobacterium tuberculosis-infected macrophages through selective autophagy.Shuxin Liang et al.Autophagy, 16(8), 1453-1467 (2019-11-13) BH3 mimetic-elicited CaPawel E Ferdek et al.Cell death & disease, 8(3), e2640-e2640 (2017-03-03) TRPC1 Deficiency Exacerbates Cerebral Ischemia/Reperfusion-Induced Neurological Injury by Potentiating Nox4-Derived Reactive Oxygen Species Generation.Ning Xu et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 51(4), 1723-1738 (2018-12-07) Taurine may not alleviate hyperglycemia-mediated endoplasmic reticulum stress in human adipocytes.Kyoung Soo Kim et al.Advances in experimental medicine and biology, 775, 395-403 (2013-02-09) Effects of ER stress on unfolded protein responses, cell survival, and viral replication in primary effusion lymphoma.Zenpei Shigemi et al.Biochemical and biophysical research communications, 469(3), 565-572 (2015-12-23) Ammonium increases Ca(2+) signalling and up-regulates expression of TRPC1 gene in astrocytes in primary cultures and in the in vivo brain.Chunguang Liang et al.Neurochemical research, 39(11), 2127-2135 (2014-08-13) TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling.Isamu Sakabe et al.Breast cancer research and treatment, 153(2), 285-297 (2015-08-14) Roselle Polyphenols Exert Potent Negative Inotropic Effects via Modulation of Intracellular Calcium Regulatory Channels in Isolated Rat Heart.Yi-Cheng Lim et al.Cardiovascular toxicology, 17(3), 251-259 (2016-07-13) The unfolded protein response impacts melanoma progression by enhancing FGF expression and can be antagonized by a chemical chaperone.Karin Eigner et al.Scientific reports, 7(1), 17498-17498 (2017-12-14) Fructose 1,6-Bisphosphatase 2 Plays a Crucial Role in the Induction and Maintenance of Long-Term Potentiation.Przemysław Duda et al.Cells, 9(6) (2020-06-05) SIRT1/HSF1/HSP pathway is essential for exenatide-alleviated, lipid-induced hepatic endoplasmic reticulum stress.Xiaobin Zheng et al.Hepatology (Baltimore, Md.), 66(3), 809-824 (2017-04-26) Bilirubin disrupts calcium homeostasis in neonatal hippocampal neurons: a new pathway of neurotoxicity.Rossana Rauti et al.Archives of toxicology, 94(3), 845-855 (2020-03-04) Thyroid and Glucocorticoid Hormones Promote Functional T-Tubule Development in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.Shan S Parikh et al.Circulation research, 121(12), 1323-1330 (2017-10-05) The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport.Maria L Torgersen et al.Oncotarget, 7(52), 86871-86888 (2016-11-29) IRE1α kinase-mediated unconventional protein secretion rescues misfolded CFTR and pendrin.Hak Park et al.Science advances, 6(8), eaax9914-eaax9914 (2020-03-05) Myocardial MMP-2 contributes to SERCA2a proteolysis during cardiac ischaemia-reperfusion injury.Andrej Roczkowsky et al.Cardiovascular research, 116(5), 1021-1031 (2019-08-03) The polyphenol ellagic acid exerts anti-inflammatory actions via disruption of store-operated calcium entry (SOCE) pathway activators and coupling mediators.Matthew T Murphy et al.European journal of pharmacology, 875, 173036-173036 (2020-02-27) Sphingosine-1-phosphate-activated TRPC1 channel controls chemotaxis of glioblastoma cells.Sophie Lepannetier et al.Cell calcium, 60(6), 373-383 (2016-09-18) Stress of endoplasmic reticulum modulates differentiation and lipogenesis of human adipocytes.Michal Koc et al.Biochemical and biophysical research communications, 460(3), 684-690 (2015-03-31) Possible association of CAG repeat polymorphism in KCNN3 encoding the potassium channel SK3 with oxaliplatin-induced neurotoxicity.Benjamin Anon et al.Cancer chemotherapy and pharmacology, 82(1), 149-157 (2018-05-19) mTOR inhibitors activate PERK signaling and favor viability of gastrointestinal neuroendocrine cell lines.Patricia Freis et al.Oncotarget, 8(13), 20974-20987 (2017-04-21) Inhibition of the PI 3-kinase pathway disrupts the unfolded protein response and reduces sensitivity to ER stress-dependent apoptosis.Jonathon N Winnay et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(9), 12521-12532 (2020-08-04) RGS2 promotes the translation of stress-associated proteins ATF4 and CHOP via its eIF2B-inhibitory domain.Chang-Hui Jenny Wang et al.Cellular signalling, 59, 163-170 (2019-03-04) Antihypertrophic Effects of Small Molecules that Maintain Mitochondrial ATP Levels Under Hypoxia.Hiroaki Nagai et al.EBioMedicine, 24, 147-158 (2017-09-25) Pre-malignant transformation by senescence evasion is prevented by the PERK and ATF6alpha branches of the Unfolded Protein Response.Claire Drullion et al.Cancer letters, 438, 187-196 (2018-09-15) Rictor negatively regulates high-affinity receptors for IgE-induced mast cell degranulation.Daniel Smrz et al.Journal of immunology (Baltimore, Md. : 1950), 193(12), 5924-5932 (2014-11-08) H2A Monoubiquitination Links Glucose Availability to Epigenetic Regulation of the Endoplasmic Reticulum Stress Response and Cancer Cell Death.Yilei Zhang et al.Cancer research, 80(11), 2243-2256 (2020-04-11) Photodynamic therapy with redaporfin targets the endoplasmic reticulum and Golgi apparatus.Lígia C Gomes-da-Silva et al.The EMBO journal, 37(13) (2018-05-29) Oxytocin evokes a pulsatile PGE2 release from ileum mucosa and is required for repair of intestinal epithelium after injury.Dawei Chen et al.Scientific reports, 5, 11731-11731 (2015-07-15) Brief report: stress-inducible nuclear protein 1 regulates matrix metalloproteinase 13 expression in human articular chondrocytes.Raghunatha R Yammani et al.Arthritis & rheumatology (Hoboken, N.J.), 66(5), 1266-1271 (2014-02-06) GIV/Girdin promotes cell survival during endoplasmic reticulum stress.Peter Nguyen et al.Molecular and cellular biochemistry, 453(1-2), 79-88 (2018-08-27) Cutting Edge: identification of neutrophil PGLYRP1 as a ligand for TREM-1.Christine B Read et al.Journal of immunology (Baltimore, Md. : 1950), 194(4), 1417-1421 (2015-01-18) Acetaldehyde suppresses HBV-MHC class I complex presentation on hepatocytes via induction of ER stress and Golgi fragmentation.Murali Ganesan et al.American journal of physiology. Gastrointestinal and liver physiology, 319(4), G432-G442 (2020-08-07) Aspirin metabolite sodium salicylate selectively inhibits transcriptional activity of ATF6α and downstream target genes.Fernanda L B Mügge et al.Scientific reports, 7(1), 9190-9190 (2017-08-25) Tumor necrosis factor (TNF) modulates synaptic plasticity in a concentration-dependent manner through intracellular calcium stores.Nicola Maggio et al.Journal of molecular medicine (Berlin, Germany), 96(10), 1039-1047 (2018-08-04) Activation of TRPV1 channel antagonizes diabetic nephropathy through inhibiting endoplasmic reticulum-mitochondria contact in podocytes.Xiao Wei et al.Metabolism: clinical and experimental, 105, 154182-154182 (2020-02-18) Cytoskeletal Protein 4.1R Is a Positive Regulator of the FcεRI Signaling and Chemotaxis in Mast Cells.Lubica Draberova et al.Frontiers in immunology, 10, 3068-3068 (2020-01-30) Sodium-glucose cotransporter 2 inhibitors regulate ketone body metabolism via inter-organ crosstalk.Jin Hee Kim et al.Diabetes, obesity & metabolism (2018-11-09) TRPV2 channels mediate insulin secretion induced by cell swelling in mouse pancreatic β-cells.Toshiaki Sawatani et al.American journal of physiology. Cell physiology, 316(3), C434-C443 (2019-01-17) The Traditional Medicine Banhasasim-Tang Depolarizes Pacemaker Potentials of Cultured Interstitial Cells of Cajal through M3 Muscarinic and 5-HT3 Receptors in Murine Small Intestine.Jeong Nam Kim et al.Digestion, 101(5), 536-551 (2019-06-12) GSK2656157, a PERK inhibitor, reduced LPS-induced IL-1β production through inhibiting Caspase 1 activation in macrophage-like J774.1 cells.Takashi Ando et al.Immunopharmacology and immunotoxicology, 38(4), 298-302 (2016-06-03) Partially Defective Store Operated Calcium Entry and Hem(ITAM) Signaling in Platelets of Serotonin Transporter Deficient Mice.Karen Wolf et al.PloS one, 11(1), e0147664-e0147664 (2016-01-23) The role of calcium signalling in the chondrogenic response of mesenchymal stem cells to hydrostatic pressure.A J Steward et al.European cells & materials, 28, 358-371 (2014-10-29) Misfolded proteins bind and activate death receptor 5 to trigger apoptosis during unresolved endoplasmic reticulum stress.Mable Lam et al.eLife, 9 (2020-01-07) Elucidating post-translational regulation of mouse CREB3 in Neuro2a cells.Kentaro Oh-Hashi et al.Molecular and cellular biochemistry, 448(1-2), 287-297 (2018-02-20) Inhibition of the hexosamine biosynthesis pathway potentiates cisplatin cytotoxicity by decreasing BiP expression in non-small-cell lung cancer cells.Wenshu Chen et al.Molecular carcinogenesis, 58(6), 1046-1055 (2019-02-23) Translation without eIF2 promoted by poliovirus 2A protease.Natalia Redondo et al.PloS one, 6(10), e25699-e25699 (2011-10-18) Biological activity and apoptotic signaling pathway of C11-functionalized cephalostatin 1 analogues.Mansour M Nawasreh et al.Steroids, 158, 108602-108602 (2020-02-25) No evidence for cell-to-cell transmission of the unfolded protein response in cell culture.Anna M van Ziel et al.Journal of neurochemistry, 152(2), 208-220 (2019-08-24) The Integrated Stress Response Regulates Cell Health of Cardiac Progenitors.George H Searfoss et al.Toxicological sciences : an official journal of the Society of Toxicology, 167(1), 202-210 (2018-09-15) Pancreatic stone protein/regenerating protein is a potential biomarker for endoplasmic reticulum stress in beta cells.Stephen Stone et al.Scientific reports, 9(1), 5199-5199 (2019-03-28) Calcium Uptake via Mitochondrial Uniporter Contributes to Palmitic Acid-Induced Apoptosis in Mouse Podocytes.Zeting Yuan et al.Journal of cellular biochemistry, 118(9), 2809-2818 (2017-02-10) Autophagy blockade and lysosomal membrane permeabilization contribute to lead-induced nephrotoxicity in primary rat proximal tubular cells.Xiang-Bin Song et al.Cell death & disease, 8(6), e2863-e2863 (2017-06-09) Saber Tadros et al.Cancer research, 77(20), 5503-5517 (2017-08-16)Pancreatic adenocarcinoma is moderately responsive to gemcitabine-based chemotherapy, the most widely used single-agent therapy for pancreatic cancer. Although the prognosis in pancreatic cancer remains grim in part due to poor response to therapy, previous attempts at identifying and targeting the... An NFκB Activity Calculator to Delineate Signaling Crosstalk: Type I and II Interferons Enhance NFκB via Distinct Mechanisms.Simon Mitchell et al.Frontiers in immunology, 10, 1425-1425 (2019-07-12) Preliminary Structure-Activity Relationship (SAR) of a Novel Series of Pyrazole SKF-96365 Analogues as Potential Store-Operated Calcium Entry (SOCE) Inhibitors.Camille D Dago et al.International journal of molecular sciences, 19(3) (2018-03-15) Unfolded protein response-induced dysregulation of calcium homeostasis promotes retinal degeneration in rat models of autosomal dominant retinitis pigmentosa.V Shinde et al.Cell death & disease, 7, e2085-e2085 (2016-02-06) Digitoxin enhances the growth inhibitory effects of thapsigargin and simvastatin on ER negative human breast cancer cells.Linda Saxe Einbond et al.Fitoterapia, 109, 146-154 (2015-12-23) Neuronal Store-Operated Calcium Entry and Mushroom Spine Loss in Amyloid Precursor Protein Knock-In Mouse Model of Alzheimer's Disease.Hua Zhang et al.The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(39), 13275-13286 (2015-10-02) Imaging of mitochondrial and non-mitochondrial responses in cultured rat hippocampal neurons exposed to micromolar concentrations of TMRM.Andrew Monteith et al.PloS one, 8(3), e58059-e58059 (2013-03-14) Mechanisms underlying the vasorelaxant effect of trans-4-methoxy-β-nitrostyrene in the rat mesenteric resistance arteries.Thayane Rebeca Alves-Santos et al.European journal of pharmacology, 853, 201-209 (2019-02-05) Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphocytes.Shanique K E Edwards et al.Journal of hematology & oncology, 7, 56-56 (2014-09-10) Regulation of proto-oncogene Orai3 by miR18a/b and miR34a.Ayushi Vashisht et al.Cell calcium, 75, 101-111 (2018-09-15) A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis.Steven M Moss et al.Cell host & microbe, 25(3), 454-462 (2019-03-05) High-frequency sarcomeric auto-oscillations induced by heating in living neonatal cardiomyocytes of the rat.Seine A Shintani et al.Biochemical and biophysical research communications, 457(2), 165-170 (2014-12-30) Lung immunoglobulin A immunity dysregulation in cystic fibrosis.Amandine M Collin et al.EBioMedicine, 60, 102974-102974 (2020-09-15) Thapsigargin induces apoptosis when autophagy is inhibited in HepG2 cells and both processes are regulated by ROS-dependent pathway.Congcong Wang et al.Environmental toxicology and pharmacology, 41, 167-179 (2015-12-29) Trisk 95 as a novel skin mirror for normal and diabetic systemic glucose level.Nsrein Ali et al.Scientific reports, 10(1), 12246-12246 (2020-07-24) Migration and Phagocytic Ability of Activated Microglia During Post-natal Development is Mediated by Calcium-Dependent Purinergic Signalling.Aditya Sunkaria et al.Molecular neurobiology, 53(2), 944-954 (2015-01-13) Induction of endoplasmic reticulum-derived oxidative stress by an occult infection related S surface antigen variant.In-Kyung Lee et al.World journal of gastroenterology, 21(22), 6872-6883 (2015-06-17) The vasodilatory effect of gemigliptin via activation of voltage-dependent K+ channels and SERCA pumps in aortic smooth muscle.Hee Seok Jung et al.European journal of pharmacology, 882, 173243-173243 (2020-06-15) Calreticulin Ins5 and Del52 mutations impair unfolded protein and oxidative stress responses in K562 cells expressing CALR mutants.Simona Salati et al.Scientific reports, 9(1), 10558-10558 (2019-07-25) C/EBP-β Is Differentially Affected by PPARα Agonists Fenofibric Acid and GW7647, But Does Not Change Apolipoprotein A-I Production During ER-Stress and Inflammation.Sophie E van der Krieken et al.Journal of cellular biochemistry, 118(4), 754-763 (2016-09-13) P2X7-induced zeiosis promotes osteogenic differentiation and mineralization of postmenopausal bone marrow-derived mesenchymal stem cells.José Bernardo Noronha-Matos et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(12), 5208-5222 (2014-08-30) Copper‑containing amine oxidase purified from Lathyrus sativus as a modulator of human neutrophil functions.Paola Pietrangeli et al.International journal of molecular medicine, 45(5), 1583-1590 (2020-04-24) IP3R-Mediated Compensatory Mechanism for Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Cardiac Ryanodine Receptor Deficiency.Xiaojing Luo et al.Frontiers in cell and developmental biology, 8, 772-772 (2020-09-10) Cellular stress induces TRB3/USP9x-dependent Notch activation in cancer.J Izrailit et al.Oncogene, 36(8), 1048-1057 (2016-09-07) Screening Mycobacterium tuberculosis Secreted Proteins Identifies Mpt64 as a Eukaryotic Membrane-Binding Bacterial Effector.Chelsea E Stamm et al.mSphere, 4(3) (2019-06-07) Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components.Paula Lindner et al.Cell communication and signaling : CCS, 18(1), 12-12 (2020-01-29) Integrin-linked kinase mediates force transduction in cardiomyocytes by modulating SERCA2a/PLN function.Alexandra Traister et al.Nature communications, 5, 4533-4533 (2014-09-12) Effects of PERK eIF2α Kinase Inhibitor against Toxoplasma gondii.Leonardo Augusto et al.Antimicrobial agents and chemotherapy, 62(11) (2018-09-06) Photoactivated fullerene C60 induces store-operated Ca2 entry and cytochrome c release in Jurkat cells.S M Grebinyk et al.Ukrains'kyi biokhimichnyi zhurnal (1999 ), 84(6), 58-63 (2013-02-08) Lithium Sensitive ORAI1 Expression, Store Operated CaLisann Pelzl et al.Scientific reports, 7(1), 6457-6457 (2017-07-27) Camphene isolated from essential oil of Piper cernuum (Piperaceae) induces intrinsic apoptosis in melanoma cells and displays antitumor activity in vivo.Natalia Girola et al.Biochemical and biophysical research communications, 467(4), 928-934 (2015-10-17) SERCA-inhibiting activity of C-19 terpenolides from Thapsia garganica and their possible biogenesis.Giovanni Appendino et al.Journal of natural products, 68(8), 1213-1217 (2005-08-30) Arsenite-induced endoplasmic reticulum-dependent apoptosis through disturbance of calcium homeostasis in HBE cell line.Chengzhi Chen et al.Environmental toxicology, 32(1), 197-216 (2015-12-18) Nitric oxide enhances extracellular ATP induced Ca²⁺ oscillation in HeLa cells.Yinglong Tang et al.Archives of biochemistry and biophysics, 565, 68-75 (2014-12-03) Apocynin protects endothelial cells from endoplasmic reticulum stress-induced apoptosis via IRE1α engagement.Jie Wu et al.Molecular and cellular biochemistry, 449(1-2), 257-265 (2018-04-27) Aggregation-induced integrated stress response rejuvenates culture-expanded human mesenchymal stem cells.Brent M Bijonowski et al.Biotechnology and bioengineering, 117(10), 3136-3149 (2020-06-25) Synergistic AML Cell Death Induction by Marine Cytotoxin (+)-1(R), 6(S), 1'(R), 6'(S), 11(R), 17(S)-Fistularin-3 and Bcl-2 Inhibitor Venetoclax.Cristina Florean et al.Marine drugs, 16(12) (2018-12-24) Cortical cytoskeleton dynamics regulates plasma membrane calcium ATPase isoform-2 (PMCA2) activity.Marianela G Dalghi et al.Biochimica et biophysica acta, 1864(8), 1413-1424 (2017-05-22) HMGB1 represses the anti-cancer activity of sunitinib by governing TP53 autophagic degradation via its nucleus-to-cytoplasm transport.Peihua Luo et al.Autophagy, 14(12), 2155-2170 (2018-09-13) P-REX1-Independent, Calcium-Dependent RAC1 Hyperactivation in Prostate Cancer.Martin J Baker et al.Cancers, 12(2) (2020-02-26) Fucoidan induces cancer cell apoptosis by modulating the endoplasmic reticulum stress cascades.Shaohua Chen et al.PloS one, 9(9), e108157-e108157 (2014-09-19) The adverse vascular effects of multi-walled carbon nanotubes (MWCNTs) to human vein endothelial cells (HUVECs) in vitro: role of length of MWCNTs.Jimin Long et al.Journal of nanobiotechnology, 15(1), 80-80 (2017-11-12) Reciprocal Effects of Antiretroviral Drugs Used To Treat HIV Infection on the Fibroblast Growth Factor 21/β-Klotho System.Ricardo Moure et al.Antimicrobial agents and chemotherapy, 62(6) (2018-04-18) NFAT5-sensitive Orai1 expression and store-operated CaItishri Sahu et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31(8), 3439-3448 (2017-04-28) Dual Targeting of BRAF and mTOR Signaling in Melanoma Cells with Pyridinyl Imidazole Compounds.Veronika Palušová et al.Cancers, 12(6) (2020-06-14) Lapatinib induces autophagic cell death and differentiation in acute myeloblastic leukemia.Yu-Jen Chen et al.OncoTargets and therapy, 9, 4453-4464 (2016-08-09) CSFV Infection Up-Regulates the Unfolded Protein Response to Promote Its Replication.Wencheng He et al.Frontiers in microbiology, 8, 2129-2129 (2017-11-23) Hijacking of host calreticulin is required for the white spot syndrome virus replication cycle.Apiruck Watthanasurorot et al.Journal of virology, 88(14), 8116-8128 (2014-05-09) Impaired autophagy activity is linked to elevated ER-stress and inflammation in aging adipose tissue.Amiya Kumar Ghosh et al.Aging, 8(10), 2525-2537 (2016-10-26) Microtubules Stabilization by Mutant Spastin Affects ER Morphology and Ca2+ Handling.Nicola Vajente et al.Frontiers in physiology, 10, 1544-1544 (2020-01-11) Pterostilbene Inhibits the Growth of Human Esophageal Cancer Cells by Regulating Endoplasmic Reticulum Stress.Yingtong Feng et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 38(3), 1226-1244 (2016-03-17) Multivesicular body formation enhancement and exosome release during endoplasmic reticulum stress.Soshi Kanemoto et al.Biochemical and biophysical research communications, 480(2), 166-172 (2016-10-30) TRPM7 activation potentiates SOCE in enamel cells but requires ORAI.Guilherme H Souza Bomfim et al.Cell calcium, 87, 102187-102187 (2020-03-09) CaYusuke Tsuruwaka et al.PeerJ, 5, e2894-e2894 (2017-01-31) Corosolic acid protects hepatocytes against ethanol-induced damage by modulating mitogen-activated protein kinases and activating autophagy.Xiaolan Guo et al.European journal of pharmacology, 791, 578-588 (2016-10-30) Preservation of circadian rhythms by the protein folding chaperone, BiP.Adam Pickard et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(6), 7479-7489 (2019-03-20) Inhibitory effect of donepezil on bradykinin-induced increase in the intracellular calcium concentration in cultured cortical astrocytes.Kouki Makitani et al.Journal of pharmacological sciences, 134(1), 37-44 (2017-05-14) Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II.Yosuke Osaki et al.Cell death & disease, 9(8), 808-808 (2018-07-26) Excitatory effect of bradykinin on intrinsic neurons of the rat heart.Shiho Arichi et al.Neuropeptides, 75, 65-74 (2019-05-03) Involvement of natriuretic peptide system in C2C12 myocytes.Kiyoshi Ishikawa et al.Molecular and cellular biochemistry, 456(1-2), 15-27 (2018-12-07) Activation of the endoplasmic reticulum unfolded protein response by lipid disequilibrium without disturbed proteostasis in vivo.Nicole S Hou et al.Proceedings of the National Academy of Sciences of the United States of America, 111(22), E2271-E2280 (2014-05-21) Regulation of the ER-bound transcription factor Luman/CREB3 in HEK293 cells.Kentaro Oh-Hashi et al.FEBS letters, 593(19), 2771-2778 (2019-07-11) A monoclonal antibody TrkB receptor agonist as a potential therapeutic for Huntington's disease.Daniel Todd et al.PloS one, 9(2), e87923-e87923 (2014-02-08) Optogenetic control of mRNA localization and translation in live cells.Na Yeon Kim et al.Nature cell biology, 22(3), 341-352 (2020-02-19) Wireless control of cellular function by activation of a novel protein responsive to electromagnetic fields.Vijai Krishnan et al.Scientific reports, 8(1), 8764-8764 (2018-06-10) Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity.Suneng Fu et al.Science translational medicine, 7(292), 292ra98-292ra98 (2015-06-19) Astragaloside IV alleviates heart failure via activating PPARα to switch glycolysis to fatty acid β-oxidation.Zhiwei Dong et al.Scientific reports, 7(1), 2691-2691 (2017-06-05) Lipid environment induces ER stress, TXNIP expression and inflammation in immune cells of individuals with type 2 diabetes.Anaïs Szpigel et al.Diabetologia, 61(2), 399-412 (2017-10-11) A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression.Hyoung-Soo Cho et al.Journal of immunology (Baltimore, Md. : 1950), 195(10), 4822-4831 (2015-10-16) Calcium/Ask1/MKK7/JNK2/c-Src signalling cascade mediates disruption of intestinal epithelial tight junctions by dextran sulfate sodium.Geetha Samak et al.The Biochemical journal, 465(3), 503-515 (2014-11-08) G-Protein-Coupled Estrogen Receptor (GPER)-Specific Agonist G1 Induces ER Stress Leading to Cell Death in MCF-7 Cells.Diep-Khanh Ho Vo et al.Biomolecules, 9(9) (2019-09-22) TERT attenuated ER stress-induced cell death.Toru Hosoi et al.Biochemical and biophysical research communications, 447(2), 378-382 (2014-04-22) Upregulation of 5-hydroxytryptamine receptor signaling in coronary arteries after organ culture.Chun-Yu Deng et al.PloS one, 9(9), e107128-e107128 (2014-09-10) Screening and Characterization of Drugs That Protect Corneal Endothelial Cells Against Unfolded Protein Response and Oxidative Stress.Eun Chul Kim et al.Investigative ophthalmology & visual science, 58(2), 892-900 (2017-02-06) FGF19 Protects Hepatocellular Carcinoma Cells against Endoplasmic Reticulum Stress via Activation of FGFR4-GSK3β-Nrf2 Signaling.Yong Teng et al.Cancer research, 77(22), 6215-6225 (2017-09-28) The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma.David Y A Dadey et al.Oncotarget, 7(2), 2080-2092 (2015-12-31) Estrogen receptor α/HDAC/NFAT axis for delphinidin effects on proliferation and differentiation of T lymphocytes from patients with cardiovascular risks.Ousama Dayoub et al.Scientific reports, 7(1), 9378-9378 (2017-08-26) PDK4 Augments ER-Mitochondria Contact to Dampen Skeletal Muscle Insulin Signaling During Obesity.Themis Thoudam et al.Diabetes, 68(3), 571-586 (2018-12-14) Calcium permeability of transient receptor potential canonical (TRPC) 4 channels measured by TRPC4-GCaMP6s.Juyeon Ko et al.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 21(1), 133-140 (2017-01-10) Nam Dia long, a Vietnamese folk formula, induces apoptosis in MCF-7 cells through various mechanisms of action.My-Nuong Thi Nguyen et al.BMC complementary and alternative medicine, 17(1), 522-522 (2017-12-06) Inhibition of degranulation in mast cells attached to a hydrogel through defective microtubule tracts.Atsushi Shiki et al.Experimental cell research, 381(2), 248-255 (2019-05-22) Herp depletion inhibits zearalenone-induced cell death in RAW 264.7 macrophages.Fenglei Chen et al.Toxicology in vitro : an international journal published in association with BIBRA, 32, 115-122 (2016-01-03) INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division.Rajarshi Chakrabarti et al.The Journal of cell biology, 217(1), 251-268 (2017-11-17) MRGPRX4 is a G protein-coupled receptor activated by bile acids that may contribute to cholestatic pruritus.James Meixiong et al.Proceedings of the National Academy of Sciences of the United States of America, 116(21), 10525-10530 (2019-05-10) Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules.Daryl A Bosco et al.Human molecular genetics, 19(21), 4160-4175 (2010-08-12) NF-YA overexpression protects from glutamine deprivation.Diletta Dolfini et al.Biochimica et biophysica acta. Molecular cell research, 1867(2), 118571-118571 (2019-11-11) Lysosomal dysfunction induced by changes in albumin's tertiary structure: Potential key factor in protein toxicity during diabetic nephropathy.Rafael Medina-Navarro et al.Life sciences, 230, 197-207 (2019-06-01) Thioesterase-mediated control of cellular calcium homeostasis enables hepatic ER stress.Baran A Ersoy et al.The Journal of clinical investigation, 128(1), 141-156 (2017-12-05) 50 years to diagnosis: Autosomal dominant tubular aggregate myopathy caused by a novel STIM1 mutation.Maggie C Walter et al.Neuromuscular disorders : NMD, 25(7), 577-584 (2015-05-09) Fast calcium wave inhibits excessive apoptosis during epithelial wound healing.Cristian Justet et al.Cell and tissue research, 365(2), 343-356 (2016-03-19) DREADD-based synthetic control of chondrocyte calcium signaling in vitro.Ryan C McDonough et al.Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 37(7), 1518-1529 (2019-03-26) FAK activates AKT-mTOR signaling to promote the growth and progression of MMTV-Wnt1-driven basal-like mammary tumors.Ritama Paul et al.Breast cancer research : BCR, 22(1), 59-59 (2020-06-05) Mitochondrial Division Inhibitor 1 (mdivi-1) Protects Neurons against Excitotoxicity through the Modulation of Mitochondrial Function and Intracellular CaAsier Ruiz et al.Frontiers in molecular neuroscience, 11, 3-3 (2018-02-02) TRPA1 and TRPV1 are required for lidocaine-evoked calcium influx and neuropeptide release but not cytotoxicity in mouse sensory neurons.Mirjam Eberhardt et al.PloS one, 12(11), e0188008-e0188008 (2017-11-16) Distinct autophagosomal-lysosomal fusion mechanism revealed by thapsigargin-induced autophagy arrest.Ian G Ganley et al.Molecular cell, 42(6), 731-743 (2011-06-28) Triggered Ca2+ influx is required for extended synaptotagmin 1-induced ER-plasma membrane tethering.Olof Idevall-Hagren et al.The EMBO journal, 34(17), 2291-2305 (2015-07-24) Artemisinin-resistant mutants of Toxoplasma gondii have altered calcium homeostasis.Kisaburo Nagamune et al.Antimicrobial agents and chemotherapy, 51(11), 3816-3823 (2007-08-19) The AF-1-deficient estrogen receptor ERα46 isoform is frequently expressed in human breast tumors.Elodie Chantalat et al.Breast cancer research : BCR, 18(1), 123-123 (2016-12-09) Coagulation factor XI induces Ca2+ response and accelerates cell migration in vascular smooth muscle cells via proteinase-activated receptor 1.Wenhua Liu et al.American journal of physiology. Cell physiology, 316(3), C377-C392 (2018-12-20) The effect of axotomy on firing and ultrastructure of the crayfish mechanoreceptor neurons and satellite glial cells.M V Rudkovskii et al.Molecular and cellular neurosciences, 107, 103534-103534 (2020-07-28) Glucose-mediated inhibition of calcium-activated potassium channels limits α-cell calcium influx and glucagon secretion.Matthew T Dickerson et al.American journal of physiology. Endocrinology and metabolism, 316(4), E646-E659 (2019-01-30) Mitochondrial division inhibitor 1 disrupts oligodendrocyte Ca2+ homeostasis and mitochondrial function.Asier Ruiz et al.Glia, 68(9), 1743-1756 (2020-02-16) The natural flavonoid myricetin inhibits gastric HYuu Miyazaki et al.European journal of pharmacology, 820, 217-221 (2017-12-24) Phosphorylation switches protein disulfide isomerase activity to maintain proteostasis and attenuate ER stress.Jiaojiao Yu et al.The EMBO journal, 39(10), e103841-e103841 (2020-03-10) The TRPC channel blocker SKF 96365 inhibits glioblastoma cell growth by enhancing reverse mode of the Na(+) /Ca(2+) exchanger and increasing intracellular Ca(2+).M Song et al.British journal of pharmacology, 171(14), 3432-3447 (2014-03-20) Transient receptor potential channel 6 knockdown prevents apoptosis of renal tubular epithelial cells upon oxidative stress via autophagy activation.Xin Hou et al.Cell death & disease, 9(10), 1015-1015 (2018-10-05) DIPK2A promotes STX17- and VAMP7-mediated autophagosome-lysosome fusion by binding to VAMP7B.Xiaoyu Tian et al.Autophagy, 16(5), 797-810 (2019-06-30) Unfolded protein response in hypothalamic cultures of wild-type and ATF6α-knockout mice.Wenjun Lu et al.Neuroscience letters, 612, 199-203 (2015-12-29) Regulation of Molecular Chaperone GRP78 by Hepatitis B Virus: Control of Viral Replication and Cell Survival.Wangqin Shu et al.Molecular and cellular biology, 40(3) (2019-11-13) Enhanced Orai1 and STIM1 expression as well as store operated Ca2+ entry in therapy resistant ovary carcinoma cells.Sebastian Schmidt et al.Oncotarget, 5(13), 4799-4810 (2014-07-13) Estrogen receptor-alpha 36 mediates the anti-apoptotic effect of estradiol in triple negative breast cancer cells via a membrane-associated mechanism.Reyhaan A Chaudhri et al.Biochimica et biophysica acta, 1843(11), 2796-2806 (2014-08-12) Bcl-xL inhibition by molecular-targeting drugs sensitizes human pancreatic cancer cells to TRAIL.Yoko Hari et al.Oncotarget, 6(39), 41902-41915 (2015-10-28) Hypoxia-Inducible Factor 1α (HIF-1α) Counteracts the Acute Death of Cells Transplanted into the Injured Spinal Cord.Brian T David et al.eNeuro, 7(3) (2019-09-07) The natural flavonoid myricetin inhibits gastric HYuu Miyazaki et al.European journal of pharmacology, 820, 217-221 (2017-12-24) The Role of IRE-XBP1 Pathway in Regulation of Retinal Pigment Epithelium Tight Junctions.Jacey H Ma et al.Investigative ophthalmology & visual science, 57(13), 5244-5252 (2016-10-05) The melatonin receptor antagonist luzindole induces Ca2+ mobilization, reactive oxygen species generation and impairs trypsin secretion in mouse pancreatic acinar cells.Matias Estaras et al.Biochimica et biophysica acta. General subjects, 1863(11), 129407-129407 (2019-08-06) Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB.Ruslana Bryk et al.PLoS pathogens, 16(6), e1008567-e1008567 (2020-06-24) Characterization of the functional and anatomical differences in the atrial and ventricular myocardium from three species of elasmobranch fishes: smooth dogfish (Mustelus canis), sandbar shark (Carcharhinus plumbeus), and clearnose skate (Raja eglanteria).Julie Larsen et al.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 187(2), 291-313 (2016-10-01) Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy.Pamela Bella et al.EMBO molecular medicine, 12(1), e11019-e11019 (2019-12-04) Emodin inhibits tonic tension through suppressing PKCδ-mediated inhibition of myosin phosphatase in rat isolated thoracic aorta.Kyung-Min Lim et al.British journal of pharmacology, 171(18), 4300-4310 (2014-06-10) Store-Operated Calcium Entry Contributes to Cisplatin-Induced Cell Death in Non-Small Cell Lung Carcinoma.Roberta Gualdani et al.Cancers, 11(3) (2019-03-29) Fingolimod sensitizes EGFR wild‑type non‑small cell lung cancer cells to lapatinib or sorafenib and induces cell cycle arrest.Kohki Ota et al.Oncology reports, 42(1), 231-242 (2019-05-07) Calcium Influx through Plasma-Membrane Nanoruptures Drives Axon Degeneration in a Model of Multiple Sclerosis.Maarten E Witte et al.Neuron, 101(4), 615-624 (2019-01-29) Sylwia Bartoszewska et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(10), 11541-11554 (2019-07-18)During endoplasmic reticulum (ER) stress conditions, an adaptive signaling network termed the unfolded protein response (UPR) is activated. The UPR's function is to increase ER protein-folding capacity in order to attenuate ER stress, restore ER homeostasis, and, most importantly, promote... Pharmacological and Biochemical Characterization of TLQP-21 Activation of a Binding Site on CHO Cells.Laura Molteni et al.Frontiers in pharmacology, 8, 167-167 (2017-04-21) A novel PMCA3 mutation in an ataxic patient with hypomorphic phosphomannomutase 2 (PMM2) heterozygote mutations: Biochemical characterization of the pump defect.Mattia Vicario et al.Biochimica et biophysica acta, 1863(12), 3303-3312 (2017-08-16) Autophagy induction by thiostrepton improves the efficacy of immunogenic chemotherapy.Yan Wang et al.Journal for immunotherapy of cancer, 8(1) (2020-03-30) High fat diet induces microbiota-dependent silencing of enteroendocrine cells.Lihua Ye et al.eLife, 8 (2019-12-04) Oxidative stress facilitates cell death by inhibiting Orai1-mediated Ca2+ entry in brain capillary endothelial cells.Hideto Yamamura et al.Biochemical and biophysical research communications, 523(1), 153-158 (2019-12-17) Multi-walled carbon nanotubes act as a chemokine and recruit macrophages by activating the PLC/IP3/CRAC channel signaling pathway.Hui Li et al.Scientific reports, 7(1), 226-226 (2017-03-24) Carboxypeptidase E (CPE) inhibits the secretion and activity of Wnt3a.N Skalka et al.Oncogene, 35(50), 6416-6428 (2016-07-05) Parallel Signaling through IRE1α and PERK Regulates Pancreatic Neuroendocrine Tumor Growth and Survival.Paul C Moore et al.Cancer research, 79(24), 6190-6203 (2019-11-02) Kurarinone from Sophora Flavescens Roots Triggers ATF4 Activation and Cytostatic Effects Through PERK Phosphorylation.Sakiko Nishikawa et al.Molecules (Basel, Switzerland), 24(17) (2019-08-30) NHA2 promotes cyst development in an in vitro model of polycystic kidney disease.Hari Prasad et al.The Journal of physiology, 597(2), 499-519 (2018-09-23) TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling.Isamu Sakabe et al.Breast cancer research and treatment, 153(2), 285-297 (2015-08-14) Asymmetrical dimethylarginine induces dysfunction of insulin signal transduction via endoplasmic reticulum stress in the liver of diabetic rats.Ni Qiu et al.Life sciences, 260, 118373-118373 (2020-09-09) Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay.Sonja Aits et al.Autophagy, 11(8), 1408-1424 (2015-06-27) Probing the settlement signals of Amphibalanus amphitrite.Mado Kotsiri et al.Biofouling, 34(5), 492-506 (2018-05-25) Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence.Hanlin Zhang et al.Molecular cell, 76(1), 110-125 (2019-09-03) The melatonin receptor antagonist luzindole induces the activation of cellular stress responses and decreases viability of rat pancreatic stellate cells.Matias Estaras et al.Journal of applied toxicology : JAT, 40(11), 1554-1565 (2020-06-23) The E3 Ubiquitin Ligase SIAH1 Targets MyD88 for Proteasomal Degradation During Dengue Virus Infection.Ashleigh R Murphy Schafer et al.Frontiers in microbiology, 11, 24-24 (2020-03-03) Resveratrol, an activator of SIRT1, improves ER stress by increasing clusterin expression in HepG2 cells.Jinmi Lee et al.Cell stress & chaperones, 24(4), 825-833 (2019-06-12) Methamphetamine increases dopamine release in the nucleus accumbens through calcium-dependent processes.Jordan T Yorgason et al.Psychopharmacology, 237(5), 1317-1330 (2020-01-23) Endoplasmic reticulum and lysosomal Ca²⁺ stores are remodelled in GBA1-linked Parkinson disease patient fibroblasts.Bethan S Kilpatrick et al.Cell calcium, 59(1), 12-20 (2015-12-23) Polychlorinated biphenyl 19 blocks the most common form of store-operated CaKeimin Lee et al.Naunyn-Schmiedeberg's archives of pharmacology, 390(12), 1221-1228 (2017-09-03) Store-Operated Calcium Channels Are Involved in Spontaneous Slow Calcium Oscillations in Striatal Neurons.Satomi Kikuta et al.Frontiers in cellular neuroscience, 13, 547-547 (2020-01-11) TERT attenuated ER stress-induced cell death.Toru Hosoi et al.Biochemical and biophysical research communications, 447(2), 378-382 (2014-04-22) Upregulation of 5-hydroxytryptamine receptor signaling in coronary arteries after organ culture.Chun-Yu Deng et al.PloS one, 9(9), e107128-e107128 (2014-09-10) Screening and Characterization of Drugs That Protect Corneal Endothelial Cells Against Unfolded Protein Response and Oxidative Stress.Eun Chul Kim et al.Investigative ophthalmology & visual science, 58(2), 892-900 (2017-02-06) FGF19 Protects Hepatocellular Carcinoma Cells against Endoplasmic Reticulum Stress via Activation of FGFR4-GSK3β-Nrf2 Signaling.Yong Teng et al.Cancer research, 77(22), 6215-6225 (2017-09-28) The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma.David Y A Dadey et al.Oncotarget, 7(2), 2080-2092 (2015-12-31) Estrogen receptor α/HDAC/NFAT axis for delphinidin effects on proliferation and differentiation of T lymphocytes from patients with cardiovascular risks.Ousama Dayoub et al.Scientific reports, 7(1), 9378-9378 (2017-08-26) Ca(2+) monitoring in Plasmodium falciparum using the yellow cameleon-Nano biosensor.Kishor Pandey et al.Scientific reports, 6, 23454-23454 (2016-03-24) Native store-operated calcium channels are functionally expressed in mouse spinal cord dorsal horn neurons and regulate resting calcium homeostasis.Jingsheng Xia et al.The Journal of physiology, 592(16), 3443-3461 (2014-05-27) Endoplasmic reticulum stress is involved in ventilator-induced lung injury in mice via the IRE1α-TRAF2-NF-κB pathway.Liu Ye et al.International immunopharmacology, 78, 106069-106069 (2019-12-17) Inhibition of transcription by dactinomycin reveals a new characteristic of immunogenic cell stress.Juliette Humeau et al.EMBO molecular medicine, 12(5), e11622-e11622 (2020-04-24) AMP kinase promotes glioblastoma bioenergetics and tumour growth.Rishi Raj Chhipa et al.Nature cell biology, 20(7), 823-835 (2018-06-20) Shikonin, dually functions as a proteasome inhibitor and a necroptosis inducer in multiple myeloma cells.Naoko Wada et al.International journal of oncology, 46(3), 963-972 (2014-12-23) PDK4 Augments ER-Mitochondria Contact to Dampen Skeletal Muscle Insulin Signaling During Obesity.Themis Thoudam et al.Diabetes, 68(3), 571-586 (2018-12-14) Depolarization of pacemaker potentials by caffeic acid phenethyl ester in interstitial cells of Cajal from the murine small intestine.Jeong Nam Kim et al.Canadian journal of physiology and pharmacology, 98(4), 201-210 (2019-11-07) SOCE mediated by STIM and Orai is essential for pacemaker activity in the interstitial cells of Cajal in the gastrointestinal tract.Haifeng Zheng et al.Science signaling, 11(534) (2018-06-14) Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer.Nora Pällmann et al.Oncogene, 38(35), 6301-6318 (2019-07-18) The endoplasmic reticulum-localized protein TBL2 interacts with the 60S ribosomal subunit.Yoshinori Tsukumo et al.Biochemical and biophysical research communications, 462(4), 383-388 (2015-05-16) Chaperones ameliorate beta cell dysfunction associated with human islet amyloid polypeptide overexpression.Lisa Cadavez et al.PloS one, 9(7), e101797-e101797 (2014-07-11) Downregulation of HLA-ABC expression through promoter hypermethylation and downmodulation of MIC-A/B surface expression in LMP2A-positive epithelial carcinoma cell lines.Shweta Singh et al.Scientific reports, 10(1), 5415-5415 (2020-03-28) P-REX1-Independent, Calcium-Dependent RAC1 Hyperactivation in Prostate Cancer.Martin J Baker et al.Cancers, 12(2) (2020-02-26) Fucoidan induces cancer cell apoptosis by modulating the endoplasmic reticulum stress cascades.Shaohua Chen et al.PloS one, 9(9), e108157-e108157 (2014-09-19) Non-Dioxin-Like Polychlorinated Biphenyls Inhibit G-Protein Coupled Receptor-Mediated Ca2+ Signaling by Blocking Store-Operated Ca2+ Entry.Se-Young Choi et al.PloS one, 11(3), e0150921-e0150921 (2016-03-11) Transcriptional and post-transcriptional regulation of transmembrane protein 132A.Kentaro Oh-Hashi et al.Molecular and cellular biochemistry, 405(1-2), 291-299 (2015-05-01) Prolonged Endoplasmic Reticulum-Stressed Hepatocytes Drive an Alternative Macrophage Polarization.Fangming Xiu et al.Shock (Augusta, Ga.), 44(1), 44-51 (2015-05-07) CD147 up-regulates calcium-induced chemotaxis, adhesion ability and invasiveness of human neutrophils via a TRPM-7-mediated mechanism.Cong-Hua Wang et al.Rheumatology (Oxford, England), 53(12), 2288-2296 (2014-07-24) PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice.Yi-Chun Chen et al.Diabetologia, 63(3), 561-576 (2020-01-28) STIM1-dependent CaYun-Wen Chen et al.Scientific reports, 7(1), 11523-11523 (2017-09-16) The GRP78/BiP inhibitor HA15 synergizes with mitotane action against adrenocortical carcinoma cells through convergent activation of ER stress pathways.Carmen Ruggiero et al.Molecular and cellular endocrinology, 474, 57-64 (2018-02-24) Mitochondrial CaJulien Prudent et al.Scientific reports, 6, 36570-36570 (2016-11-09) Characterization of Endoplasmic Reticulum (ER) in Human Pluripotent Stem Cells Revealed Increased Susceptibility to Cell Death upon ER Stress.Tae Won Ha et al.Cells, 9(5) (2020-05-03) PtdIns3P controls mTORC1 signaling through lysosomal positioning.Zhi Hong et al.The Journal of cell biology, 216(12), 4217-4233 (2017-10-17) Betty Y K Law et al.Frontiers in pharmacology, 8, 388-388 (2017-07-04)Resistance of cancer cells to chemotherapy remains a significant problem in oncology. Mechanisms regulating programmed cell death, including apoptosis, autophagy or necrosis, in the treatment of cancers have been extensively investigated over the last few decades. Autophagy is now emerging... Intracellular Ca(2+) release from endoplasmic reticulum regulates slow wave currents and pacemaker activity of interstitial cells of Cajal.Mei Hong Zhu et al.American journal of physiology. Cell physiology, 308(8), C608-C620 (2015-01-30) αMSH promotes preadipocyte proliferation by alleviating ER stress-induced leptin resistance and by activating Notch1 signal in mice.Lu Gan et al.Biochimica et biophysica acta, 1863(1), 231-238 (2016-10-09) Inhibition of the mitochondrial calcium uniporter prevents IL-13 and allergen-mediated airway epithelial apoptosis and loss of barrier function.Sara C Sebag et al.Experimental cell research, 362(2), 400-411 (2017-12-12) Lacrimal Gland Myoepithelial Cells Are Altered in a Mouse Model of Dry Eye Disease.Laura García-Posadas et al.The American journal of pathology, 190(10), 2067-2079 (2020-07-18) Fumonisin B1 Inhibits Endoplasmic Reticulum Stress Associated-apoptosis After FoscanPDT Combined with C6-Pyridinium Ceramide or Fenretinide.Nithin B Boppana et al.Anticancer research, 37(2), 455-463 (2017-02-10) Calcium signaling recruits substrate transporters GLUT4 and CD36 to the sarcolemma without increasing cardiac substrate uptake.Angin Y, Schwenk RW, Nergiz-Unal R, et al. American Journal of Physiology. Endocrinology and Metabolism, 307(2), E225-E236 (2014) PERK-mediated Autophagy in Osteosarcoma Cells Resists ER Stress-induced Cell Apoptosis.Guang-rong Ji et al.International journal of biological sciences, 11(7), 803-812 (2015-06-17) A complex of Neuroplastin and Plasma Membrane CaMark Korthals et al.Scientific reports, 7(1), 8358-8358 (2017-08-23) Characterisation of mice lacking the inflammatory caspases-1/11/12 reveals no contribution of caspase-12 to cell death and sepsis.Ranja Salvamoser et al.Cell death and differentiation, 26(6), 1124-1137 (2018-08-30) Nicotinic acetylcholine receptor signaling regulates inositol-requiring enzyme 1α activation to protect β-cells against terminal unfolded protein response under irremediable endoplasmic reticulum stress.Tatsuya Ishibashi et al.Journal of diabetes investigation, 11(4), 801-813 (2020-01-12) Whole-blood transcriptomic responses to lumacaftor/ivacaftor therapy in cystic fibrosis.Benjamin T Kopp et al.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 19(2), 245-254 (2019-09-03) Germline compound heterozygous poly-glutamine deletion in USF3 may be involved in predisposition to heritable and sporadic epithelial thyroid carcinoma.Ying Ni et al.Human molecular genetics, 26(2), 243-257 (2016-12-25) Contrasting actions of group I metabotropic glutamate receptors in distinct mouse striatal neurones.John G Partridge et al.The Journal of physiology, 592(13), 2721-2733 (2014-04-09) Inhibition of degranulation in mast cells attached to a hydrogel through defective microtubule tracts.Atsushi Shiki et al.Experimental cell research, 381(2), 248-255 (2019-05-22) Herp depletion inhibits zearalenone-induced cell death in RAW 264.7 macrophages.Fenglei Chen et al.Toxicology in vitro : an international journal published in association with BIBRA, 32, 115-122 (2016-01-03) Advanced oxidation protein products induce apoptosis in podocytes through induction of endoplasmic reticulum stress.Guang Rong et al.Journal of physiology and biochemistry, 71(3), 455-470 (2015-07-23) Polypeptide N-acetylgalactosaminyltransferase 18 non-catalytically regulates the ER homeostasis and O-glycosylation.Aidong Shan et al.Biochimica et biophysica acta. General subjects, 1863(5), 870-882 (2019-02-25) Activation of the unfolded protein response in sarcoma cells treated with rapamycin or temsirolimus.Joseph W Briggs et al.PloS one, 12(9), e0185089-e0185089 (2017-09-20) Unbiased Cell-based Screening in a Neuronal Cell Model of Batten Disease Highlights an Interaction between Ca2+ Homeostasis, Autophagy, and CLN3 Protein Function.Uma Chandrachud et al.The Journal of biological chemistry, 290(23), 14361-14380 (2015-04-17) Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development.Rafael Falcón-Moya et al.Nature communications, 11(1), 4388-4388 (2020-09-03) Overexpression of NRF1-742 or NRF1-772 Reduces Arsenic-Induced Cytotoxicity and Apoptosis in Human HaCaT Keratinocytes.Shuai Wang et al.International journal of molecular sciences, 21(6) (2020-03-20) Activation of PERK-Nrf2 oncogenic signaling promotes Mdm2-mediated Rb degradation in persistently infected HCV culture.Yucel Aydin et al.Scientific reports, 7(1), 9223-9223 (2017-08-25) Pancreatic β cells overexpressing hIAPP impaired mitophagy and unbalanced mitochondrial dynamics.Miriam García Hernández et al.Cell death & disease, 9(5), 481-481 (2018-05-01) T cell receptor signaling results in ERK-dependent Ser163 phosphorylation of lymphocyte phosphatase-associated phosphoprotein.Natalia Kruglova et al.Biochemical and biophysical research communications, 519(3), 559-565 (2019-09-21) Mechanism of antimalarial action of the synthetic trioxolane RBX11160 (OZ277).Anne-Catrin Uhlemann et al.Antimicrobial agents and chemotherapy, 51(2), 667-672 (2006-12-06) Hepatitis B virus X protein inhibits apoptosis by modulating endoplasmic reticulum stress response.Jia Li et al.Oncotarget, 8(56), 96027-96034 (2017-12-10) Thapsigargin directly induces the mitochondrial permeability transition.P Korge et al.European journal of biochemistry, 265(1), 273-280 (1999-09-22) Loss of function of the ALS protein SigR1 leads to ER pathology associated with defective autophagy and lipid raft disturbances.J T Vollrath et al.Cell death & disease, 5, e1290-e1290 (2014-06-13) Voltage-gated calcium channel blockers deregulate macroautophagy in cardiomyocytes.Charumathi Pushparaj et al.The international journal of biochemistry & cell biology, 68, 166-175 (2015-10-03) Advanced maturation of human cardiac tissue grown from pluripotent stem cells.Kacey Ronaldson-Bouchard et al.Nature, 556(7700), 239-243 (2018-04-06) Ca2+ release-activated Ca2+ channels are responsible for histamine-induced Ca2+ entry, permeability increase, and interleukin synthesis in lymphatic endothelial cells.Hongjiang Si et al.American journal of physiology. Heart and circulatory physiology, 318(5), H1283-H1295 (2020-04-11) Japanese encephalitis virus activates autophagy through XBP1 and ATF6 ER stress sensors in neuronal cells.Manish Sharma et al.The Journal of general virology, 98(5), 1027-1039 (2017-05-26) CORM-401 induces calcium signalling, NO increase and activation of pentose phosphate pathway in endothelial cells.Patrycja Kaczara et al.The FEBS journal, 285(7), 1346-1358 (2018-02-22) SERCA directs cell migration and branching across species and germ layers.Danielle V Bower et al.Biology open, 6(10), 1458-1471 (2017-08-20) Inhibition of gastric H+,K+-ATPase by 4-(2-butyl-6,7-dichloro-2-cyclopentylindan-1-on-5-yl)oxybutyric acid (DCPIB), an inhibitor of volume-regulated anion channel.Takuto Fujii et al.European journal of pharmacology, 765, 34-41 (2015-08-19) Auto-regulation of Secretory Flux by Sensing and Responding to the Folded Cargo Protein Load in the Endoplasmic Reticulum.Advait Subramanian et al.Cell, 176(6), 1461-1476 (2019-03-09) Ginkgolide K protects the heart against endoplasmic reticulum stress injury by activating the inositol-requiring enzyme 1α/X box-binding protein-1 pathway.Shoubao Wang et al.British journal of pharmacology, 173(15), 2402-2418 (2016-05-18) ATP-Induced Increase in Intracellular Calcium Levels and Subsequent Activation of mTOR as Regulators of Skeletal Muscle Hypertrophy.Naoki Ito et al.International journal of molecular sciences, 19(9) (2018-09-21) Nifedipine Upregulates ATF6-α, Caspases -12, -3, and -7 Implicating Lipotoxicity-Associated Renal ER Stress.Chiung-Chi Peng et al.International journal of molecular sciences, 21(9) (2020-05-06) Hepatitis B Surface Antigen Activates Unfolded Protein Response in Forming Ground Glass Hepatocytes of Chronic Hepatitis B.Yao Li et al.Viruses, 11(4) (2019-04-28) Hydrogen sulfide regulates muscle RING finger-1 protein S-sulfhydration at Cys44 to prevent cardiac structural damage in diabetic cardiomyopathy.Xiaojiao Sun et al.British journal of pharmacology, 177(4), 836-856 (2019-02-09) G-Protein-Coupled Estrogen Receptor (GPER)-Specific Agonist G1 Induces ER Stress Leading to Cell Death in MCF-7 Cells.Diep-Khanh Ho Vo et al.Biomolecules, 9(9) (2019-09-22) Stress-induced upregulation of VLDL receptor alters Wnt-signaling in neurons.Kai Kysenius et al.Experimental cell research, 340(2), 238-247 (2016-01-12) Elevation of extracellular Ca2+ induces store-operated calcium entry via calcium-sensing receptors: a pathway contributes to the proliferation of osteoblasts.Fen Hu et al.PloS one, 9(9), e107217-e107217 (2014-09-26) TRPC1 regulates calcium-activated chloride channels in salivary gland cells.Yuyang Sun et al.Journal of cellular physiology, 230(11), 2848-2856 (2015-04-23) Endoplasmic reticulum stress and autophagy contribute to cadmium-induced cytotoxicity in retinal pigment epithelial cells.Lingmin Zhang et al.Toxicology letters, 311, 105-113 (2019-05-06) Activation of intestinal olfactory receptor stimulates glucagon-like peptide-1 secretion in enteroendocrine cells and attenuates hyperglycemia in type 2 diabetic mice.Ki-Suk Kim et al.Scientific reports, 7(1), 13978-13978 (2017-10-27) The unfolded protein response selectively targets active smoothened mutants.Suresh Marada et al.Molecular and cellular biology, 33(12), 2375-2387 (2013-04-11) Distinct autophagosomal-lysosomal fusion mechanism revealed by thapsigargin-induced autophagy arrest.Ian G Ganley et al.Molecular cell, 42(6), 731-743 (2011-06-28) The AF-1-deficient estrogen receptor ERα46 isoform is frequently expressed in human breast tumors.Elodie Chantalat et al.Breast cancer research : BCR, 18(1), 123-123 (2016-12-09) Coagulation factor XI induces Ca2+ response and accelerates cell migration in vascular smooth muscle cells via proteinase-activated receptor 1.Wenhua Liu et al.American journal of physiology. Cell physiology, 316(3), C377-C392 (2018-12-20) Live-Cell Assays for Cell Stress Responses Reveal New Patterns of Cell Signaling Caused by Mutations in Rhodopsin, α-Synuclein and TDP-43.Kevin M Harlen et al.Frontiers in cellular neuroscience, 13, 535-535 (2020-01-11) Calcium Release from Endoplasmic Reticulum Involves Calmodulin-Mediated NADPH Oxidase-Derived Reactive Oxygen Species Production in Endothelial Cells.Ryugo Sakurada et al.International journal of molecular sciences, 20(7) (2019-04-17) The vasorelaxant effect of mitiglinide via activation of voltage-dependent KHongliang Li et al.Life sciences, 188, 1-9 (2017-09-01) HKH40A downregulates GRP78/BiP expression in cancer cells.T Kosakowska-Cholody et al.Cell death & disease, 5, e1240-e1240 (2014-05-24) Rhododendrol, a depigmentation-inducing phenolic compound, exerts melanocyte cytotoxicity via a tyrosinase-dependent mechanism.Minoru Sasaki et al.Pigment cell & melanoma research, 27(5), 754-763 (2014-06-04) The effect of axotomy on firing and ultrastructure of the crayfish mechanoreceptor neurons and satellite glial cells.M V Rudkovskii et al.Molecular and cellular neurosciences, 107, 103534-103534 (2020-07-28) Cephalostatin 1 analogues activate apoptosis via the endoplasmic reticulum stress signaling pathway.Lubna H Tahtamouni et al.European journal of pharmacology, 818, 400-409 (2017-11-21) Human leucine zipper protein promotes hepatic steatosisMinsoo Kang et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31(6), 2548-2561 (2017-03-02) Magnesium Acts as a Second Messenger in the Regulation of NMDA Receptor-Mediated CREB Signaling in Neurons.Hailong Hou et al.Molecular neurobiology, 57(6), 2539-2550 (2020-03-28) Obesity-related cellular stressors regulate gonadotropin releasing hormone gene expression via c-Fos/AP-1.Noah J Levi et al.Molecular and cellular endocrinology, 478, 97-105 (2018-08-01) Calcium permeability of transient receptor potential canonical (TRPC) 4 channels measured by TRPC4-GCaMP6s.Juyeon Ko et al.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 21(1), 133-140 (2017-01-10) Nam Dia long, a Vietnamese folk formula, induces apoptosis in MCF-7 cells through various mechanisms of action.My-Nuong Thi Nguyen et al.BMC complementary and alternative medicine, 17(1), 522-522 (2017-12-06) Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer.Daniel J McGrail et al.Cancer cell, 37(3), 371-386 (2020-02-29) P2X7-induced zeiosis promotes osteogenic differentiation and mineralization of postmenopausal bone marrow-derived mesenchymal stem cells.José Bernardo Noronha-Matos et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(12), 5208-5222 (2014-08-30) Copper‑containing amine oxidase purified from Lathyrus sativus as a modulator of human neutrophil functions.Paola Pietrangeli et al.International journal of molecular medicine, 45(5), 1583-1590 (2020-04-24) Optogenetic stimulation of phosphoinositides reveals a critical role of primary cilia in eye pressure regulation.Philipp P Prosseda et al.Science advances, 6(18), eaay8699-eaay8699 (2020-06-05) Evaluation of a dansyl-based amino acid DNSBA as an imaging probe for apoptosis detection.Min Tang et al.Apoptosis : an international journal on programmed cell death, 20(3), 410-420 (2015-01-19) Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin.Claudia Nussbaum et al.Nature communications, 6, 6416-6416 (2015-04-04) Dual Targeting of BRAF and mTOR Signaling in Melanoma Cells with Pyridinyl Imidazole Compounds.Veronika Palušová et al.Cancers, 12(6) (2020-06-14) Lapatinib induces autophagic cell death and differentiation in acute myeloblastic leukemia.Yu-Jen Chen et al.OncoTargets and therapy, 9, 4453-4464 (2016-08-09) Roles of sarcoplasmic reticulum Ca2+ ATPase pump in the impairments of lymphatic contractile activity in a metabolic syndrome rat model.Yang Lee et al.Scientific reports, 10(1), 12320-12320 (2020-07-25) Cycloheximide promotes paraptosis induced by inhibition of cyclophilins in glioblastoma multiforme.Lin Wang et al.Cell death & disease, 8(5), e2807-e2807 (2017-05-19) Characterization of novel store-operated calcium entry effectors.Alaeddine Djillani et al.Biochimica et biophysica acta, 1843(10), 2341-2347 (2014-03-25) Pterostilbene Inhibits the Growth of Human Esophageal Cancer Cells by Regulating Endoplasmic Reticulum Stress.Yingtong Feng et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 38(3), 1226-1244 (2016-03-17) Multivesicular body formation enhancement and exosome release during endoplasmic reticulum stress.Soshi Kanemoto et al.Biochemical and biophysical research communications, 480(2), 166-172 (2016-10-30) TRPM7 activation potentiates SOCE in enamel cells but requires ORAI.Guilherme H Souza Bomfim et al.Cell calcium, 87, 102187-102187 (2020-03-09) Excitatory effect of bradykinin on intrinsic neurons of the rat heart.Shiho Arichi et al.Neuropeptides, 75, 65-74 (2019-05-03) Inhibitory effect of donepezil on bradykinin-induced increase in the intracellular calcium concentration in cultured cortical astrocytes.Kouki Makitani et al.Journal of pharmacological sciences, 134(1), 37-44 (2017-05-14) Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II.Yosuke Osaki et al.Cell death & disease, 9(8), 808-808 (2018-07-26) Corosolic acid protects hepatocytes against ethanol-induced damage by modulating mitogen-activated protein kinases and activating autophagy.Xiaolan Guo et al.European journal of pharmacology, 791, 578-588 (2016-10-30) Involvement of natriuretic peptide system in C2C12 myocytes.Kiyoshi Ishikawa et al.Molecular and cellular biochemistry, 456(1-2), 15-27 (2018-12-07) RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy.Qi Luan et al.Autophagy, 11(7), 975-994 (2015-05-29) Dental enamel cells express functional SOCE channels.Meerim K Nurbaeva et al.Scientific reports, 5, 15803-15803 (2015-10-31) Both RyRs and TPCs are required for NAADP-induced intracellular Ca²⁺ release.Julia V Gerasimenko et al.Cell calcium, 58(3), 237-245 (2015-06-24) SpiCee: A Genetic Tool for Subcellular and Cell-Specific Calcium Manipulation.Oriol Ros et al.Cell reports, 32(3), 107934-107934 (2020-07-23) SERCA and PMCA pumps contribute to the deregulation of Ca2+ homeostasis in human CF epithelial cells.Réginald Philippe et al.Biochimica et biophysica acta, 1853(5), 892-903 (2015-02-11) Proteasome Inhibition Suppresses Dengue Virus Egress in Antibody Dependent Infection.Milly M Choy et al.PLoS neglected tropical diseases, 9(11), e0004058-e0004058 (2015-11-14) 1,25-hydroxyvitamin D3 decreases endoplasmic reticulum stress-induced inflammatory response in mammary epithelial cells.Gaiping Wen et al.PloS one, 15(2), e0228945-e0228945 (2020-02-11) Induction of store-operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP/TAZ.Zhijun Liu et al.Oncogene, 38(1), 120-139 (2018-08-08) Activation of Toll-like receptor 4 (TLR4) attenuates adaptive thermogenesis via endoplasmic reticulum stress.Meshail Okla et al.The Journal of biological chemistry, 290(44), 26476-26490 (2015-09-16) PRKCSH contributes to tumorigenesis by selective boosting of IRE1 signaling pathway.Gu-Choul Shin et al.Nature communications, 10(1), 3185-3185 (2019-07-20) Phosphorylation of eukaryotic initiation factor-2α (eIF2α) in autophagy.Juliette Humeau et al.Cell death & disease, 11(6), 433-433 (2020-06-10) Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia.Peter van Galen et al.Cell reports, 25(5), 1109-1117 (2018-11-01) Menthol relieves acid reflux inflammation by regulating TRPV1 in esophageal epithelial cells.Zhiming Zhang et al.Biochemical and biophysical research communications (2020-02-23) NFAT5-sensitive Orai1 expression and store-operated CaItishri Sahu et al.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 31(8), 3439-3448 (2017-04-28) Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia.Matteo Marchesini et al.Cell chemical biology, 27(6), 678-697 (2020-05-11) Growth arrest and DNA damage-inducible 45α protects against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet.Naoki Tanaka et al.Biochimica et biophysica acta, 1863(12), 3170-3182 (2017-08-29) Allergy immunotherapy restores airway epithelial barrier dysfunction through suppressing IL-25 -induced endoplasmic reticulum stress in asthma.Xiefang Yuan et al.Scientific reports, 8(1), 7950-7950 (2018-05-23) Very Low-Density Lipoproteins of Metabolic Syndrome Modulates STIM1, Suppresses Store-Operated Calcium Entry, and Deranges Myofilament Proteins in Atrial Myocytes.Yi-Lin Shiou et al.Journal of clinical medicine, 8(6) (2019-06-23) Activation of TRPC1 Channel by Metabotropic Glutamate Receptor mGluR5 Modulates Synaptic Plasticity and Spatial Working Memory.Sophie Lepannetier et al.Frontiers in cellular neuroscience, 12, 318-318 (2018-10-03) CSFV Infection Up-Regulates the Unfolded Protein Response to Promote Its Replication.Wencheng He et al.Frontiers in microbiology, 8, 2129-2129 (2017-11-23) Reciprocal Effects of Antiretroviral Drugs Used To Treat HIV Infection on the Fibroblast Growth Factor 21/β-Klotho System.Ricardo Moure et al.Antimicrobial agents and chemotherapy, 62(6) (2018-04-18) Hijacking of host calreticulin is required for the white spot syndrome virus replication cycle.Apiruck Watthanasurorot et al.Journal of virology, 88(14), 8116-8128 (2014-05-09) Impaired autophagy activity is linked to elevated ER-stress and inflammation in aging adipose tissue.Amiya Kumar Ghosh et al.Aging, 8(10), 2525-2537 (2016-10-26) Microtubules Stabilization by Mutant Spastin Affects ER Morphology and Ca2+ Handling.Nicola Vajente et al.Frontiers in physiology, 10, 1544-1544 (2020-01-11) Attenuation of the unfolded protein response and endoplasmic reticulum stress after mechanical unloading in dilated cardiomyopathy.Estibaliz Castillero et al.American journal of physiology. Heart and circulatory physiology, 309(3), H459-H470 (2015-06-10) Intracellular proliferation of Anaplasma phagocytophilum is promoted via modulation of endoplasmic reticulum stress signaling in host cells.Yuko Yoshikawa et al.Microbiology and immunology, 64(4), 270-279 (2020-01-08) ATF6 mediates a pro-inflammatory synergy between ER stress and TLR activation in the pathogenesis of liver ischemia-reperfusion injury.J Rao et al.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 14(7), 1552-1561 (2014-06-07) Role of protein phosphatase 2A in PTTH-stimulated prothoracic glands of the silkworm, Bombyx mori.Shi-Hong Gu et al.General and comparative endocrinology, 274, 97-105 (2019-01-23) ATF4-Dependent NRF2 Transcriptional Regulation Promotes Antioxidant Protection during Endoplasmic Reticulum Stress.Carmen Sarcinelli et al.Cancers, 12(3) (2020-03-04) Effects of calcium signaling on coagulation factor VIIa-induced proliferation and migration of the SW620 colon cancer cell line.Ying Wu et al.Molecular medicine reports, 10(6), 3021-3026 (2014-10-18) Involvement of TRPC1 in Nampt-induced cardiomyocyte hypertrophy through the activation of ER stress.J Li et al.Cellular and molecular biology (Noisy-le-Grand, France), 63(4), 33-37 (2017-05-10) TP53INP2-related basal autophagy is involved in the growth and malignant progression in human liposarcoma cells.Yamei Hu et al.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 88, 562-568 (2017-01-29) Thrombin regulates the ability of Schwann cells to support neuritogenesis and to maintain the integrity of the nodes of Ranvier.Elena Pompili et al.European journal of histochemistry : EJH, 64(2) (2020-04-03) DRP1-mediated mitochondrial shape controls calcium homeostasis and muscle mass.Giulia Favaro et al.Nature communications, 10(1), 2576-2576 (2019-06-14) Role of Ca2(+)-ATPases in regulation of cellular Ca2+ signalling, as studied with the selective microsomal Ca2(+)-ATPase inhibitor, thapsigargin.O Thastrup Agents and actions, 29(1-2), 8-15 (1990-01-01) Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks.Benjamin D Stein et al.Cell reports, 29(10), 3331-3348 (2019-12-05) CaMKII/calpain interaction mediates ischemia/reperfusion injury in isolated rat hearts.Hong-Ting Lu et al.Cell death & disease, 11(5), 388-388 (2020-05-23) CaYusuke Tsuruwaka et al.PeerJ, 5, e2894-e2894 (2017-01-31) Follistatin Protects Against Glomerular Mesangial Cell Apoptosis and Oxidative Stress to Ameliorate Chronic Kidney Disease.Neel Mehta et al.Antioxidants & redox signaling, 31(8), 551-571 (2019-06-12) Effect of advanced glycation end product on paraoxonase 2 expression: Its impact on endoplasmic reticulum stress and inflammation in HUVECs.Ramya Ravi et al.Life sciences, 246, 117397-117397 (2020-02-08) Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory.Silvia Natale et al.Molecular neurobiology, 57(5), 2358-2376 (2020-02-13) Resveratrol-induced autophagy is dependent on IPTomas Luyten et al.Biochimica et biophysica acta, 1864(6), 947-956 (2017-03-04) Resveratrol alleviates inflammatory injury and enhances the apoptosis of fibroblast‑like synoviocytes via mitochondrial dysfunction and ER stress in rats with adjuvant arthritis.Jinsen Lu et al.Molecular medicine reports, 20(1), 463-472 (2019-06-11) Neuromuscular electrical stimulation improves skeletal muscle regeneration through satellite cell fusion with myofibers in healthy elderly subjects.Ester Sara Di Filippo et al.Journal of applied physiology (Bethesda, Md. : 1985), 123(3), 501-512 (2017-06-03) Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle.Ivan Toral-Ojeda et al.Expert reviews in molecular medicine, 18, e7-e7 (2016-04-09) The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs.Xiaopei Cao et al.American journal of translational research, 11(2), 641-654 (2019-03-23) Increased Confinement and Polydispersity of STIM1 and Orai1 after Ca2+ Store Depletion.Xianan Qin et al.Biophysical journal, 118(1), 70-84 (2019-12-11) Adenine suppresses IgE-mediated mast cell activation.Prashanta Silwal et al.Molecular immunology, 65(2), 242-249 (2015-02-24) Generation and Role of Oscillatory Contractions in Mouse Airway Smooth Muscle.Hao Xu et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 47(4), 1546-1555 (2018-06-26) GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.Makoto Shigeto et al.The Journal of clinical investigation, 125(12), 4714-4728 (2015-11-17) Alpha-1 adrenoreceptors modulate GABA release onto ventral tegmental area dopamine neurons.Maria C Velásquez-Martínez et al.Neuropharmacology, 88, 110-121 (2014-09-28) Thapsigargin blocks Pseudomonas aeruginosa homoserine lactone-induced apoptosis in airway epithelia.Christian Schwarzer et al.American journal of physiology. Cell physiology, 306(9), C844-C855 (2014-03-07) Mitochondrial glycerol 3-phosphate facilitates bumblebee pre-flight thermogenesis.Stewart W C Masson et al.Scientific reports, 7(1), 13107-13107 (2017-10-14) Prolonged Endoplasmic Reticulum-Stressed Hepatocytes Drive an Alternative Macrophage Polarization.Fangming Xiu et al.Shock (Augusta, Ga.), 44(1), 44-51 (2015-05-07) STIM1-dependent CaYun-Wen Chen et al.Scientific reports, 7(1), 11523-11523 (2017-09-16) The GRP78/BiP inhibitor HA15 synergizes with mitotane action against adrenocortical carcinoma cells through convergent activation of ER stress pathways.Carmen Ruggiero et al.Molecular and cellular endocrinology, 474, 57-64 (2018-02-24) A complex of Neuroplastin and Plasma Membrane CaMark Korthals et al.Scientific reports, 7(1), 8358-8358 (2017-08-23) Characterisation of mice lacking the inflammatory caspases-1/11/12 reveals no contribution of caspase-12 to cell death and sepsis.Ranja Salvamoser et al.Cell death and differentiation, 26(6), 1124-1137 (2018-08-30) Nicotinic acetylcholine receptor signaling regulates inositol-requiring enzyme 1α activation to protect β-cells against terminal unfolded protein response under irremediable endoplasmic reticulum stress.Tatsuya Ishibashi et al.Journal of diabetes investigation, 11(4), 801-813 (2020-01-12) SERCA and PMCA pumps contribute to the deregulation of Ca2+ homeostasis in human CF epithelial cells.Réginald Philippe et al.Biochimica et biophysica acta, 1853(5), 892-903 (2015-02-11) DRP1-mediated mitochondrial shape controls calcium homeostasis and muscle mass.Giulia Favaro et al.Nature communications, 10(1), 2576-2576 (2019-06-14) Role of Ca2(+)-ATPases in regulation of cellular Ca2+ signalling, as studied with the selective microsomal Ca2(+)-ATPase inhibitor, thapsigargin.O Thastrup Agents and actions, 29(1-2), 8-15 (1990-01-01) Quantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks.Benjamin D Stein et al.Cell reports, 29(10), 3331-3348 (2019-12-05) CaMKII/calpain interaction mediates ischemia/reperfusion injury in isolated rat hearts.Hong-Ting Lu et al.Cell death & disease, 11(5), 388-388 (2020-05-23) Activation of Toll-like receptor 4 (TLR4) attenuates adaptive thermogenesis via endoplasmic reticulum stress.Meshail Okla et al.The Journal of biological chemistry, 290(44), 26476-26490 (2015-09-16) PRKCSH contributes to tumorigenesis by selective boosting of IRE1 signaling pathway.Gu-Choul Shin et al.Nature communications, 10(1), 3185-3185 (2019-07-20) Follistatin Protects Against Glomerular Mesangial Cell Apoptosis and Oxidative Stress to Ameliorate Chronic Kidney Disease.Neel Mehta et al.Antioxidants & redox signaling, 31(8), 551-571 (2019-06-12) Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia.Peter van Galen et al.Cell reports, 25(5), 1109-1117 (2018-11-01) Menthol relieves acid reflux inflammation by regulating TRPV1 in esophageal epithelial cells.Zhiming Zhang et al.Biochemical and biophysical research communications (2020-02-23) Effect of advanced glycation end product on paraoxonase 2 expression: Its impact on endoplasmic reticulum stress and inflammation in HUVECs.Ramya Ravi et al.Life sciences, 246, 117397-117397 (2020-02-08) Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory.Silvia Natale et al.Molecular neurobiology, 57(5), 2358-2376 (2020-02-13) Resveratrol-induced autophagy is dependent on IPTomas Luyten et al.Biochimica et biophysica acta, 1864(6), 947-956 (2017-03-04) Resveratrol alleviates inflammatory injury and enhances the apoptosis of fibroblast‑like synoviocytes via mitochondrial dysfunction and ER stress in rats with adjuvant arthritis.Jinsen Lu et al.Molecular medicine reports, 20(1), 463-472 (2019-06-11) Sertraline induces endoplasmic reticulum stress in hepatic cells.Si Chen et al.Toxicology, 322, 78-88 (2014-05-29) Apomorphine prevents LPS-induced IL-23 p19 mRNA expression via inhibition of JNK and ATF4 in HAPI cells.Hirokazu Hara et al.European journal of pharmacology, 795, 108-114 (2016-12-13) Generation and Role of Oscillatory Contractions in Mouse Airway Smooth Muscle.Hao Xu et al.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 47(4), 1546-1555 (2018-06-26) Functional Translatome Proteomics Reveal Converging and Dose-Dependent Regulation by mTORC1 and eIF2α.Kevin Klann et al.Molecular cell, 77(4), 913-925 (2019-12-10) Store-operated Ca(2+) entry in rhabdomyosarcoma cells.Evi Schmid et al.Biochemical and biophysical research communications, 477(1), 129-136 (2016-06-14) FRET biosensors reveal AKAP-mediated shaping of subcellular PKA activity and a novel mode of Ca(2+)/PKA crosstalk.Micah B Schott et al.Cellular signalling, 28(4), 294-306 (2016-01-17) Endoplasmic reticulum stress as a novel mechanism in amiodarone-induced destructive thyroiditis.Angela Lombardi et al.The Journal of clinical endocrinology and metabolism, 100(1), E1-10 (2014-10-09)

备注